GREMLIN Database
YQBK - Uncharacterized protein YqbK
UniProt: P45927 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 466 (420)
Sequences: 991 (852)
Seq/√Len: 41.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
375_I450_V5.2891.00
407_V444_F4.5061.00
342_S346_E4.4331.00
38_A211_F4.0211.00
78_E289_W3.3551.00
400_T422_E3.0811.00
426_D451_Q3.0501.00
343_V346_E3.0341.00
109_A113_G3.0011.00
257_S287_T2.8601.00
238_V266_I2.8151.00
224_A287_T2.8011.00
265_G373_D2.7441.00
40_P89_Y2.6721.00
375_I418_L2.6341.00
456_A459_F2.5921.00
293_A308_Y2.5661.00
435_I438_N2.5531.00
238_V242_K2.5411.00
240_F252_V2.5371.00
372_L450_V2.5361.00
234_K256_L2.5351.00
440_D454_D2.5061.00
126_N134_D2.4861.00
255_V291_A2.4551.00
237_F254_G2.4531.00
14_R324_V2.4451.00
208_Y237_F2.4001.00
211_F214_A2.3961.00
253_Q294_S2.3721.00
374_A414_Y2.2801.00
241_I254_G2.2381.00
159_K164_T2.2261.00
39_L86_V2.2221.00
52_I64_V2.1640.99
216_E243_R2.1300.99
240_F244_L2.1280.99
161_V165_G2.0910.99
288_A292_G2.0820.99
379_L411_I2.0810.99
21_F369_V2.0620.99
164_T167_G2.0300.99
399_A404_L2.0190.99
424_I450_V2.0090.99
308_Y311_A1.9990.99
419_Q424_I1.9770.99
350_N457_E1.9640.99
398_P455_A1.9590.99
47_E50_K1.9570.99
14_R346_E1.9430.99
253_Q366_N1.9360.99
113_G198_G1.9230.99
59_D62_K1.8860.99
107_A121_I1.8620.98
365_K442_D1.8450.98
215_A223_I1.8350.98
35_G84_N1.8330.98
447_D462_N1.7860.98
145_D149_V1.7680.98
94_G99_A1.7670.98
111_Y115_K1.7620.98
14_R320_N1.7590.98
152_A162_T1.7530.98
204_T207_D1.7330.97
36_T85_T1.7130.97
134_D148_T1.7030.97
113_G117_N1.7020.97
76_L86_V1.7000.97
428_D431_N1.6910.97
113_G116_G1.6870.97
245_R373_D1.6860.97
151_K154_E1.6790.97
368_I452_P1.6560.97
133_V145_D1.6440.96
47_E63_K1.6390.96
45_W115_K1.6190.96
160_Y164_T1.6190.96
53_S85_T1.6160.96
159_K165_G1.6050.96
320_N324_V1.6040.96
47_E90_R1.5900.96
23_T362_M1.5730.95
25_A28_R1.5500.95
129_D132_K1.5410.95
39_L76_L1.5380.95
434_T449_A1.5360.95
210_A213_E1.5340.95
107_A195_L1.5240.95
242_K263_H1.4860.94
211_F215_A1.4720.94
326_R333_L1.4670.93
378_D414_Y1.4490.93
144_V147_Q1.4480.93
388_K407_V1.4450.93
94_G97_A1.4350.93
38_A223_I1.4240.92
415_L450_V1.4210.92
223_I254_G1.4200.92
79_A292_G1.4140.92
187_L191_S1.4090.92
405_Q408_K1.3910.91
223_I240_F1.3900.91
159_K162_T1.3780.91
293_A345_V1.3600.91
20_N462_N1.3460.90
319_D322_E1.3400.90
257_S298_T1.3320.90
268_N351_S1.3270.89
93_E101_I1.3170.89
363_F372_L1.3120.89
13_E324_V1.3110.89
157_P167_G1.3100.89
38_A215_A1.3050.89
434_T447_D1.3040.89
414_Y418_L1.2990.88
433_I437_L1.2980.88
139_L142_S1.2950.88
267_I294_S1.2920.88
222_T294_S1.2910.88
273_V289_W1.2840.88
417_V421_N1.2840.88
327_L350_N1.2820.88
117_N198_G1.2820.88
45_W111_Y1.2760.87
21_F376_N1.2730.87
188_P191_S1.2680.87
158_N161_V1.2680.87
350_N365_K1.2490.86
21_F337_D1.2480.86
434_T439_N1.2370.86
122_S138_Y1.2340.86
37_V79_A1.2270.85
187_L190_T1.2250.85
46_G90_R1.2250.85
157_P164_T1.2230.85
96_R99_A1.2210.85
415_L424_I1.2180.85
446_I461_F1.2140.85
154_E158_N1.2090.84
435_I446_I1.2080.84
152_A164_T1.2070.84
429_S435_I1.2050.84
155_L161_V1.2040.84
38_A89_Y1.2020.84
186_A190_T1.1990.84
418_L421_N1.1970.84
159_K163_F1.1910.84
17_I459_F1.1860.83
49_K89_Y1.1830.83
365_K457_E1.1820.83
262_D359_K1.1790.83
154_E161_V1.1740.83
151_K156_K1.1710.82
400_T425_T1.1620.82
211_F218_E1.1460.81
80_M86_V1.1420.81
155_L159_K1.1420.81
104_G331_E1.1330.80
31_A374_A1.1320.80
322_E377_N1.1310.80
29_V378_D1.1300.80
157_P162_T1.1290.80
387_I394_G1.1270.80
272_G286_A1.1250.80
29_V382_Q1.1210.80
226_P257_S1.1200.80
143_E146_K1.1170.79
255_V294_S1.1150.79
432_D436_A1.1130.79
186_A189_A1.1090.79
327_L365_K1.1060.79
159_K166_K1.1010.78
231_E235_A1.1000.78
292_G296_G1.0980.78
367_K398_P1.0980.78
374_A378_D1.0890.78
189_A193_I1.0890.78
158_N164_T1.0820.77
124_T136_T1.0810.77
35_G221_D1.0700.76
95_L99_A1.0580.75
332_F345_V1.0560.75
138_Y144_V1.0550.75
327_L335_T1.0540.75
37_V291_A1.0530.75
368_I454_D1.0520.75
203_P210_A1.0520.75
434_T438_N1.0490.75
451_Q455_A1.0440.75
136_T143_E1.0370.74
286_A334_F1.0360.74
448_L461_F1.0290.73
14_R327_L1.0290.73
130_S204_T1.0280.73
418_L423_G1.0240.73
211_F217_T1.0240.73
31_A414_Y1.0200.73
216_E244_L1.0190.73
404_L456_A1.0190.73
147_Q150_S1.0150.72
305_F365_K1.0150.72
415_L448_L1.0140.72
155_L158_N1.0110.72
432_D435_I1.0090.72
207_D366_N1.0080.72
287_T298_T1.0030.71
149_V152_A0.9990.71
302_S394_G0.9980.71
119_I152_A0.9950.71
106_K212_L0.9940.71
46_G113_G0.9920.71
119_I138_Y0.9920.71
298_T370_R0.9910.71
241_I252_V0.9850.70
181_E184_S0.9810.70
108_T197_G0.9790.70
115_K119_I0.9780.70
365_K454_D0.9770.69
189_A196_S0.9770.69
195_L198_G0.9750.69
272_G285_K0.9740.69
151_K159_K0.9710.69
182_D197_G0.9670.69
97_A101_I0.9650.69
374_A418_L0.9630.68
48_V92_T0.9620.68
145_D150_S0.9610.68
48_V112_G0.9600.68
116_G119_I0.9590.68
180_P185_G0.9540.68
135_V145_D0.9540.68
139_L143_E0.9500.67
17_I452_P0.9470.67
412_T416_S0.9470.67
294_S366_N0.9440.67
91_L277_D0.9430.67
190_T195_L0.9420.67
379_L446_I0.9410.67
160_Y163_F0.9400.66
136_T141_Q0.9390.66
433_I439_N0.9370.66
124_T127_V0.9350.66
109_A116_G0.9340.66
116_G198_G0.9320.66
269_V272_G0.9280.65
401_N427_F0.9220.65
158_N162_T0.9220.65
145_D148_T0.9220.65
144_V149_V0.9160.64
188_P193_I0.9160.64
416_S429_S0.9140.64
290_V366_N0.9120.64
46_G198_G0.9100.64
257_S285_K0.9090.64
206_A210_A0.9080.64
423_G452_P0.9080.64
244_L252_V0.9080.64
74_L78_E0.9040.63
112_G115_K0.8980.63
46_G64_V0.8960.63
12_K460_Y0.8950.63
216_E240_F0.8950.63
74_L277_D0.8950.63
387_I456_A0.8930.62
407_V456_A0.8910.62
353_T359_K0.8900.62
442_D455_A0.8890.62
427_F432_D0.8880.62
323_I333_L0.8850.62
152_A155_L0.8820.61
398_P456_A0.8800.61
150_S153_E0.8770.61
119_I139_L0.8770.61
147_Q300_N0.8750.61
187_L192_G0.8750.61
348_D352_L0.8680.60
52_I163_F0.8670.60
432_D438_N0.8600.59
76_L88_L0.8600.59
185_G191_S0.8590.59
431_N439_N0.8580.59
326_R331_E0.8520.59
40_P225_L0.8510.59
94_G199_T0.8500.59
323_I327_L0.8500.59
253_Q267_I0.8490.59
35_G378_D0.8470.58
114_T200_D0.8440.58
54_I80_M0.8430.58
17_I40_P0.8430.58
70_D231_E0.8430.58
76_L80_M0.8410.58
105_V110_L0.8370.57
152_A163_F0.8350.57
323_I335_T0.8350.57
137_T145_D0.8340.57
13_E328_S0.8330.57
126_N129_D0.8320.57
83_A86_V0.8300.57
267_I332_F0.8290.57
144_V388_K0.8280.57
14_R323_I0.8270.56
291_A422_E0.8270.56
396_D399_A0.8260.56
332_F396_D0.8260.56
290_V345_V0.8250.56
236_T319_D0.8250.56
93_E99_A0.8210.56
156_K161_V0.8210.56
69_D197_G0.8200.56
138_Y143_E0.8200.56
325_E329_N0.8190.56
123_I190_T0.8190.56
132_K149_V0.8170.56
175_L180_P0.8150.55
89_Y211_F0.8140.55
103_E108_T0.8130.55
298_T327_L0.8090.55
93_E97_A0.8090.55
261_G315_L0.8050.54
184_S191_S0.8030.54
427_F433_I0.8010.54
388_K394_G0.8000.54
107_A123_I0.8000.54
203_P208_Y0.7980.54
208_Y228_E0.7970.54
375_I415_L0.7960.54
349_I365_K0.7920.53
223_I459_F0.7910.53
375_I414_Y0.7910.53
142_S149_V0.7900.53
303_L349_I0.7870.53
99_A102_S0.7860.53
41_I326_R0.7810.52
433_I438_N0.7800.52
298_T348_D0.7800.52
180_P183_V0.7760.52
327_L348_D0.7760.52
94_G98_S0.7750.52
179_A182_D0.7740.52
224_A291_A0.7730.51
297_A418_L0.7690.51
425_T451_Q0.7610.50
82_K292_G0.7590.50
205_N233_L0.7580.50
127_V135_V0.7550.50
35_G79_A0.7540.50
270_T318_I0.7520.50
433_I442_D0.7490.49
313_D444_F0.7480.49
17_I456_A0.7480.49
256_L415_L0.7470.49
339_R344_S0.7460.49
155_L164_T0.7460.49
419_Q427_F0.7460.49
419_Q426_D0.7450.49
382_Q410_L0.7440.49
32_G378_D0.7420.49
108_T162_T0.7400.48
386_L461_F0.7380.48
254_G266_I0.7380.48
150_S155_L0.7360.48
26_E223_I0.7360.48
304_T423_G0.7340.48
234_K238_V0.7330.48
205_N209_T0.7330.48
265_G272_G0.7320.48
197_G200_D0.7300.47
379_L461_F0.7290.47
266_I352_L0.7270.47
237_F240_F0.7260.47
348_D370_R0.7250.47
313_D317_R0.7230.47
426_D455_A0.7220.47
19_F461_F0.7210.47
161_V164_T0.7210.47
335_T346_E0.7170.46
51_F87_L0.7170.46
98_S108_T0.7150.46
349_I396_D0.7150.46
411_I446_I0.7130.46
239_A243_R0.7110.46
403_G456_A0.7100.46
46_G277_D0.7090.46
35_G302_S0.7090.46
318_I323_I0.7070.45
153_E156_K0.7070.45
130_S156_K0.7070.45
414_Y448_L0.7060.45
436_A447_D0.7050.45
187_L194_R0.7040.45
99_A117_N0.7020.45
133_V138_Y0.7010.45
198_G201_K0.7000.45
350_N442_D0.7000.45
79_A83_A0.6990.45
298_T365_K0.6990.45
371_V452_P0.6970.44
335_T365_K0.6960.44
398_P418_L0.6910.44
109_A115_K0.6910.44
332_F366_N0.6900.44
298_T456_A0.6880.44
302_S350_N0.6870.43
367_K371_V0.6870.43
237_F244_L0.6860.43
109_A117_N0.6850.43
121_I202_T0.6840.43
81_K310_G0.6840.43
106_K167_G0.6810.43
114_T136_T0.6800.43
108_T152_A0.6790.43
152_A159_K0.6790.43
22_K459_F0.6790.43
137_T195_L0.6780.43
237_F243_R0.6760.42
275_L284_E0.6740.42
91_L211_F0.6730.42
237_F241_I0.6730.42
226_P330_G0.6720.42
190_T193_I0.6710.42
365_K396_D0.6680.42
404_L407_V0.6670.42
135_V150_S0.6660.42
137_T147_Q0.6650.41
221_D373_D0.6640.41
371_V453_V0.6640.41
332_F369_V0.6620.41
143_E182_D0.6610.41
451_Q458_K0.6600.41
271_G455_A0.6570.41
85_T353_T0.6550.41
269_V286_A0.6470.40
93_E229_D0.6460.40
75_L82_K0.6440.40
396_D458_K0.6430.39
142_S145_D0.6420.39
226_P457_E0.6410.39
114_T175_L0.6410.39
203_P212_L0.6390.39
115_K118_D0.6370.39
204_T209_T0.6370.39
135_V163_F0.6370.39
181_E295_A0.6370.39
255_V295_A0.6370.39
330_G350_N0.6360.39
153_E159_K0.6360.39
199_T207_D0.6350.39
78_E275_L0.6340.39
148_T186_A0.6340.39
302_S455_A0.6330.39
18_Y398_P0.6330.39
114_T129_D0.6330.39
327_L333_L0.6320.39
190_T197_G0.6290.38
103_E153_E0.6280.38
129_D196_S0.6280.38
410_L413_Q0.6270.38
432_D458_K0.6240.38
60_L413_Q0.6240.38
150_S154_E0.6240.38
307_E332_F0.6220.38
191_S199_T0.6220.38
180_P189_A0.6210.38
62_K375_I0.6210.38
198_G203_P0.6190.37
258_N268_N0.6180.37
433_I436_A0.6180.37
100_D121_I0.6180.37
136_T145_D0.6170.37
272_G388_K0.6150.37
163_F255_V0.6140.37
416_S433_I0.6130.37
143_E147_Q0.6120.37
223_I237_F0.6110.37
76_L79_A0.6110.37
365_K455_A0.6100.37
78_E288_A0.6090.36
54_I112_G0.6090.36
137_T158_N0.6090.36
100_D181_E0.6080.36
18_Y460_Y0.6070.36
360_N363_F0.6070.36
43_S61_N0.6050.36
192_G195_L0.6030.36
425_T453_V0.6020.36
327_L455_A0.6020.36
119_I142_S0.6010.36
208_Y406_F0.6000.36
40_P253_Q0.5990.36
90_R240_F0.5990.36
139_L149_V0.5970.35
420_D432_D0.5970.35
448_L463_V0.5970.35
302_S349_I0.5970.35
120_I139_L0.5960.35
312_V321_D0.5960.35
95_L98_S0.5960.35
321_D324_V0.5950.35
436_A439_N0.5940.35
265_G269_V0.5940.35
330_G457_E0.5940.35
97_A100_D0.5880.35
132_K136_T0.5880.35
234_K237_F0.5870.35
327_L346_E0.5860.35
107_A110_L0.5860.35
156_K167_G0.5850.34
38_A388_K0.5840.34
100_D431_N0.5830.34
63_K95_L0.5810.34
313_D336_Y0.5810.34
215_A254_G0.5790.34
127_V155_L0.5780.34
371_V418_L0.5770.34
167_G231_E0.5770.34
434_T437_L0.5760.34
222_T253_Q0.5760.34
200_D204_T0.5750.34
331_E411_I0.5740.34
29_V34_R0.5730.33
123_I207_D0.5710.33
100_D166_K0.5700.33
98_S189_A0.5690.33
305_F335_T0.5690.33
332_F397_V0.5680.33
106_K175_L0.5670.33
137_T149_V0.5670.33
41_I369_V0.5670.33
20_N411_I0.5650.33
134_D157_P0.5650.33
327_L394_G0.5650.33
151_K158_N0.5610.32
126_N144_V0.5610.32
179_A187_L0.5600.32
365_K458_K0.5600.32
184_S187_L0.5600.32
365_K451_Q0.5580.32
58_E62_K0.5580.32
63_K186_A0.5570.32
254_G415_L0.5570.32
181_E185_G0.5560.32
108_T120_I0.5560.32
306_V349_I0.5540.32
303_L348_D0.5540.32
125_E134_D0.5530.32
142_S146_K0.5530.32
368_I371_V0.5520.32
121_I137_T0.5510.32
106_K120_I0.5510.32
137_T175_L0.5500.32
43_S73_L0.5500.32
359_K372_L0.5500.32
64_V88_L0.5470.31
328_S404_L0.5470.31
303_L306_V0.5460.31
17_I307_E0.5450.31
117_N196_S0.5440.31
135_V138_Y0.5440.31
12_K20_N0.5440.31
215_A218_E0.5430.31
302_S365_K0.5420.31
46_G109_A0.5400.31
233_L310_G0.5390.31
114_T117_N0.5390.31
200_D203_P0.5370.31
16_G370_R0.5360.30
142_S189_A0.5350.30
301_Q305_F0.5340.30
141_Q146_K0.5330.30
274_L283_P0.5320.30
388_K456_A0.5320.30
255_V290_V0.5310.30
404_L419_Q0.5300.30
212_L222_T0.5300.30
239_A266_I0.5290.30
320_N335_T0.5280.30
234_K245_R0.5270.30
116_G183_V0.5270.30
152_A161_V0.5260.30
184_S190_T0.5260.30
435_I439_N0.5230.29
257_S327_L0.5230.29
41_I51_F0.5220.29
83_A302_S0.5220.29
348_D442_D0.5210.29
181_E197_G0.5200.29
188_P192_G0.5200.29
14_R380_T0.5200.29
54_I118_D0.5190.29
184_S375_I0.5190.29
372_L452_P0.5180.29
122_S136_T0.5180.29
123_I135_V0.5170.29
175_L181_E0.5160.29
51_F214_A0.5160.29
411_I416_S0.5160.29
32_G62_K0.5150.29
229_D322_E0.5150.29
267_I366_N0.5140.29
365_K404_L0.5140.29
106_K204_T0.5130.29
243_R255_V0.5130.29
403_G442_D0.5120.29
15_A396_D0.5120.29
209_T215_A0.5120.29
121_I296_G0.5110.28
133_V150_S0.5100.28
23_T406_F0.5090.28
160_Y165_G0.5090.28
98_S153_E0.5080.28
113_G118_D0.5070.28
156_K164_T0.5070.28
230_N239_A0.5060.28
226_P306_V0.5050.28
65_G109_A0.5050.28
454_D457_E0.5050.28
97_A102_S0.5050.28
151_K157_P0.5040.28
135_V155_L0.5040.28
29_V32_G0.5040.28
54_I329_N0.5040.28
262_D353_T0.5030.28
397_V400_T0.5030.28
51_F80_M0.5030.28
415_L453_V0.5020.28
415_L419_Q0.5020.28
296_G332_F0.5020.28
401_N439_N0.5010.28
106_K191_S0.5000.28
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3hxlA 1 0.8863 100 0.288 Contact Map
3lmlA 1 0.9227 100 0.296 Contact Map
3j2mU 1 0.8498 100 0.309 Contact Map
3j9qA 8 0.7189 100 0.471 Contact Map
3foaA 1 0.5751 100 0.584 Contact Map
3fo8D 4 0.4077 18.3 0.972 Contact Map
1pnoA 1 0.3691 11.6 0.975 Contact Map
4hrzA 2 0.2253 11.1 0.975 Contact Map
3qdsA 4 0.2339 9.2 0.976 Contact Map
2ofcA 4 0.2339 7.6 0.977 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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