GREMLIN Database
YQBB - Uncharacterized protein YqbB
UniProt: P45918 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 305 (239)
Sequences: 757 (669)
Seq/√Len: 43.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
231_R275_C5.5291.00
222_H230_P5.1671.00
231_R234_H4.6621.00
169_S177_T4.0061.00
225_G274_H3.8581.00
220_W275_C3.8321.00
217_K243_G3.5351.00
164_A174_I3.3091.00
188_R191_T3.0871.00
194_I272_N3.0711.00
209_Y279_P2.9331.00
220_W261_R2.8201.00
237_L242_I2.8201.00
209_Y277_L2.8021.00
221_R278_S2.7331.00
225_G230_P2.5861.00
225_G229_N2.5301.00
219_K241_V2.4921.00
243_G246_E2.4411.00
224_G230_P2.4271.00
223_S230_P2.3821.00
229_N274_H2.3231.00
191_T272_N2.2781.00
160_V177_T2.2431.00
146_A150_K2.1260.99
230_P274_H2.0970.99
106_L207_E1.9940.99
207_E210_A1.9680.99
142_S148_I1.9490.99
218_K242_I1.9270.99
222_H238_D1.9150.99
217_K282_D1.9040.99
220_W259_F1.8660.99
224_G238_D1.8260.98
230_P275_C1.7950.98
225_G231_R1.7420.98
207_E211_Q1.7420.98
225_G275_C1.7150.98
184_F187_E1.6820.97
222_H225_G1.6490.97
217_K241_V1.6470.97
234_H261_R1.6300.97
148_I192_T1.5820.96
193_A220_W1.5540.96
219_K278_S1.5200.95
203_A206_H1.5150.95
178_L193_A1.4790.94
220_W234_H1.4780.94
188_R192_T1.4750.94
222_H275_C1.4480.94
220_W237_L1.4260.93
261_R275_C1.4260.93
234_H259_F1.3880.92
221_R276_V1.3740.92
196_E199_A1.3680.92
220_W231_R1.3670.92
169_S173_D1.3570.91
150_K192_T1.3440.91
220_W257_C1.3340.91
218_K248_F1.3250.90
147_E153_T1.3140.90
223_S275_C1.3110.90
109_T113_M1.3060.90
231_R235_I1.3040.90
234_H242_I1.2940.89
191_T195_T1.2930.89
258_M275_C1.2790.89
203_A207_E1.2700.88
220_W258_M1.2530.88
187_E191_T1.2520.88
54_L58_H1.2480.87
193_A275_C1.2480.87
30_V33_F1.2420.87
168_G274_H1.2300.87
206_H247_E1.2120.86
84_F161_L1.2080.86
146_A192_T1.2000.85
206_H210_A1.1900.85
32_D36_K1.1900.85
242_I248_F1.1800.84
145_L149_M1.1630.83
231_R261_R1.1530.83
218_K277_L1.1420.82
257_C261_R1.1240.81
156_V181_M1.1210.81
247_E258_M1.1200.81
142_S146_A1.1180.81
218_K259_F1.1180.81
99_Q103_E1.1040.80
200_A204_A1.0970.80
222_H274_H1.0850.79
272_N280_V1.0660.78
98_F102_T1.0640.77
223_S226_K1.0570.77
234_H257_C1.0520.77
149_M153_T1.0460.76
149_M184_F1.0440.76
219_K280_V1.0420.76
242_I246_E1.0420.76
218_K245_D1.0410.76
218_K279_P1.0300.75
157_V189_A1.0210.74
160_V174_I1.0190.74
241_V280_V1.0140.74
194_I229_N1.0140.74
221_R239_G0.9940.72
184_F188_R0.9910.72
54_L101_L0.9900.72
68_F72_D0.9880.72
43_V47_E0.9820.71
111_E115_E0.9650.70
231_R259_F0.9570.70
218_K234_H0.9530.69
216_K279_P0.9480.69
194_I202_S0.9470.69
55_R59_K0.9260.67
217_K280_V0.9210.67
248_F252_G0.9090.65
168_G194_I0.9080.65
37_S41_K0.9040.65
239_G242_I0.8950.64
220_W248_F0.8920.64
198_L202_S0.8920.64
237_L275_C0.8910.64
69_V73_S0.8910.64
222_H229_N0.8890.64
220_W242_I0.8830.63
234_H252_G0.8780.63
224_G274_H0.8770.63
218_K231_R0.8640.62
146_A149_M0.8640.62
235_I275_C0.8630.61
64_G83_F0.8620.61
163_N167_N0.8620.61
143_K146_A0.8610.61
118_M122_D0.8580.61
177_T180_D0.8530.61
234_H248_F0.8510.60
160_V164_A0.8510.60
224_G275_C0.8470.60
222_H235_I0.8470.60
102_T121_I0.8440.60
36_K40_P0.8420.60
175_E190_R0.8390.59
87_N90_A0.8380.59
181_M184_F0.8340.59
48_K136_N0.8330.59
206_H244_V0.8310.58
231_R242_I0.8250.58
234_H275_C0.8210.58
198_L231_R0.8200.57
150_K153_T0.8070.56
114_A118_M0.8070.56
208_S212_S0.8060.56
76_T102_T0.8060.56
150_K234_H0.8020.56
125_V178_L0.7950.55
258_M261_R0.7920.55
223_S231_R0.7920.55
230_P238_D0.7910.55
197_V212_S0.7910.55
170_S173_D0.7910.55
216_K219_K0.7870.54
130_L135_I0.7860.54
205_Q276_V0.7850.54
146_A204_A0.7830.54
209_Y244_V0.7830.54
117_I122_D0.7810.54
213_P229_N0.7800.54
247_E257_C0.7780.54
142_S192_T0.7730.53
43_V275_C0.7720.53
135_I139_K0.7650.52
148_I196_E0.7640.52
176_L179_K0.7590.52
144_K157_V0.7580.52
176_L180_D0.7580.52
131_S134_T0.7580.52
237_L240_T0.7560.51
174_I197_V0.7530.51
190_R194_I0.7520.51
210_A245_D0.7470.51
216_K243_G0.7450.50
205_Q279_P0.7430.50
52_R183_Q0.7400.50
178_L218_K0.7380.50
32_D35_G0.7340.49
171_I198_L0.7300.49
41_K45_E0.7290.49
84_F93_D0.7260.49
235_I238_D0.7250.48
142_S150_K0.7190.48
192_T196_E0.7150.48
42_Y45_E0.7130.47
195_T204_A0.7130.47
183_Q208_S0.7000.46
191_T196_E0.6980.46
123_P178_L0.6950.46
233_N275_C0.6930.45
34_P37_S0.6930.45
213_P274_H0.6930.45
54_L197_V0.6900.45
202_S261_R0.6880.45
183_Q209_Y0.6840.45
217_K281_V0.6840.45
146_A151_L0.6830.44
195_T199_A0.6830.44
199_A231_R0.6830.44
160_V181_M0.6830.44
110_I115_E0.6820.44
151_L190_R0.6820.44
56_R159_D0.6800.44
198_L261_R0.6760.44
218_K244_V0.6760.44
76_T80_L0.6750.44
164_A169_S0.6730.44
94_F98_F0.6680.43
34_P45_E0.6680.43
137_W207_E0.6680.43
132_N136_N0.6670.43
231_R248_F0.6670.43
95_E103_E0.6660.43
192_T220_W0.6660.43
49_G52_R0.6620.43
191_T208_S0.6610.42
143_K151_L0.6610.42
226_K229_N0.6580.42
52_R213_P0.6540.42
45_E178_L0.6520.42
134_T138_I0.6500.41
54_L148_I0.6490.41
92_D96_E0.6480.41
40_P46_Y0.6470.41
115_E118_M0.6470.41
218_K247_E0.6460.41
194_I274_H0.6460.41
209_Y234_H0.6460.41
223_S238_D0.6460.41
116_V119_D0.6440.41
118_M183_Q0.6440.41
76_T168_G0.6430.41
56_R211_Q0.6430.41
30_V35_G0.6420.41
237_L281_V0.6390.40
97_E100_E0.6390.40
32_D81_L0.6390.40
161_L208_S0.6390.40
106_L204_A0.6380.40
175_E194_I0.6340.40
259_F275_C0.6270.39
41_K132_N0.6240.39
142_S196_E0.6240.39
186_R190_R0.6240.39
189_A199_A0.6230.39
127_F208_S0.6170.38
33_F37_S0.6170.38
95_E121_I0.6150.38
259_F277_L0.6150.38
198_L234_H0.6140.38
113_M117_I0.6050.37
35_G39_I0.6050.37
218_K261_R0.6030.37
213_P217_K0.6010.37
114_A120_S0.6000.37
189_A193_A0.5990.37
165_I171_I0.5990.37
113_M116_V0.5980.37
246_E251_P0.5980.37
140_D155_E0.5960.37
195_T272_N0.5960.37
226_K275_C0.5950.36
143_K152_N0.5940.36
214_A281_V0.5930.36
209_Y218_K0.5910.36
133_R136_N0.5910.36
184_F189_A0.5910.36
193_A234_H0.5890.36
150_K191_T0.5890.36
179_K189_A0.5880.36
242_I259_F0.5870.36
139_K243_G0.5870.36
83_F165_I0.5850.36
141_W198_L0.5840.35
40_P44_E0.5830.35
111_E118_M0.5810.35
175_E189_A0.5780.35
157_V178_L0.5780.35
35_G42_Y0.5740.35
113_M122_D0.5730.34
159_D163_N0.5730.34
247_E251_P0.5720.34
110_I119_D0.5720.34
212_S217_K0.5700.34
58_H182_P0.5690.34
145_L231_R0.5680.34
202_S206_H0.5680.34
133_R180_D0.5670.34
192_T234_H0.5660.34
49_G97_E0.5630.34
137_W140_D0.5620.34
205_Q209_Y0.5620.34
221_R238_D0.5590.33
230_P235_I0.5540.33
186_R199_A0.5540.33
106_L118_M0.5530.33
96_E103_E0.5530.33
115_E238_D0.5520.33
94_F176_L0.5500.33
204_A208_S0.5490.32
38_N135_I0.5460.32
59_K63_D0.5440.32
218_K251_P0.5440.32
72_D75_E0.5430.32
104_G203_A0.5430.32
224_G235_I0.5410.32
95_E165_I0.5400.32
44_E278_S0.5400.32
224_G231_R0.5390.32
175_E193_A0.5380.32
211_Q246_E0.5380.32
39_I42_Y0.5370.31
53_L93_D0.5360.31
78_K81_L0.5350.31
134_T232_E0.5340.31
178_L217_K0.5330.31
206_H277_L0.5320.31
138_I161_L0.5320.31
78_K82_V0.5320.31
65_L125_V0.5300.31
164_A168_G0.5270.31
81_L194_I0.5270.31
125_V278_S0.5260.31
50_I106_L0.5260.31
48_K214_A0.5260.31
77_L152_N0.5260.31
84_F98_F0.5260.31
157_V192_T0.5250.30
162_T169_S0.5250.30
185_D204_A0.5240.30
110_I118_M0.5230.30
61_F84_F0.5220.30
123_P155_E0.5220.30
171_I202_S0.5210.30
199_A248_F0.5200.30
121_I138_I0.5170.30
146_A152_N0.5160.30
149_M189_A0.5140.30
30_V34_P0.5090.29
62_L66_K0.5080.29
149_M235_I0.5070.29
234_H247_E0.5070.29
112_E117_I0.5070.29
240_T249_Q0.5050.29
40_P49_G0.5050.29
104_G108_Q0.5040.29
199_A275_C0.5020.29
111_E116_V0.5010.29
222_H237_L0.5000.28
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ojaA 1 0.341 18.4 0.955 Contact Map
3ojaB 1 0.3967 16.4 0.956 Contact Map
2gd5A 2 0.3934 16.4 0.956 Contact Map
1eq1A 1 0.4918 12.7 0.958 Contact Map
4y66A 1 0.4066 11.8 0.958 Contact Map
4tqlA 1 0.6984 10.4 0.96 Contact Map
4jneA 2 0.3213 10.2 0.96 Contact Map
4kblA 2 0.4033 8.6 0.961 Contact Map
4f01A 2 0.3213 8.4 0.961 Contact Map
4jioA 1 0.4557 7.9 0.962 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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