GREMLIN Database
YQAC - Uncharacterized protein YqaC
UniProt: P45900 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 178 (134)
Sequences: 5742 (3563)
Seq/√Len: 307.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
105_Q108_G4.2211.00
37_Y51_R3.4521.00
92_Q122_K3.3451.00
79_K82_F3.0451.00
75_G78_L2.6651.00
52_R70_A2.4981.00
40_D57_K2.4471.00
105_Q109_N2.2661.00
120_Q124_F2.2121.00
94_I97_E2.1251.00
119_E123_T2.0651.00
47_E50_E2.0581.00
116_S119_E2.0371.00
58_D61_I1.9821.00
101_H104_F1.9051.00
126_E130_L1.9041.00
106_R109_N1.8601.00
23_S30_H1.7481.00
99_L114_G1.7331.00
130_L134_A1.7271.00
111_V115_G1.7151.00
20_A24_K1.6641.00
110_E113_A1.6421.00
29_T58_D1.6201.00
74_W78_L1.5961.00
13_V90_I1.5771.00
7_I19_G1.5491.00
31_L58_D1.5461.00
46_R54_L1.5151.00
122_K126_E1.3681.00
130_L133_N1.3561.00
40_D54_L1.3481.00
56_E60_T1.3451.00
21_A24_K1.3291.00
100_R111_V1.3181.00
96_L115_G1.3151.00
48_I73_G1.2991.00
53_K56_E1.2971.00
113_A116_S1.2891.00
50_E53_K1.2851.00
34_D38_W1.2461.00
7_I22_L1.2091.00
20_A30_H1.2001.00
112_L118_Y1.1981.00
57_K61_I1.1911.00
131_Y135_G1.1881.00
96_L100_R1.1771.00
44_K116_S1.1651.00
121_S125_L1.1531.00
10_A95_R1.1471.00
93_D97_E1.1451.00
74_W77_N1.1331.00
8_L85_V1.1311.00
21_A25_R1.1251.00
112_L116_S1.1111.00
4_N83_D1.1021.00
36_Y58_D1.0911.00
46_R50_E1.0661.00
104_F109_N1.0481.00
12_G99_L1.0331.00
91_P94_I1.0261.00
51_R55_L1.0201.00
97_E101_H1.0171.00
65_W82_F1.0071.00
8_L129_S1.0031.00
117_K120_Q1.0021.00
129_S132_D0.9981.00
118_Y122_K0.9951.00
28_H64_K0.9911.00
92_Q129_S0.9841.00
116_S120_Q0.9801.00
87_F129_S0.9751.00
22_L66_I0.9691.00
28_H65_W0.9491.00
20_A23_S0.9451.00
36_Y40_D0.9441.00
99_L128_A0.9401.00
5_I84_L0.9281.00
104_F108_G0.9201.00
96_L111_V0.9121.00
100_R103_E0.9121.00
113_A118_Y0.9111.00
32_D35_N0.9021.00
14_G17_T0.9011.00
9_G12_G0.8981.00
27_P63_E0.8801.00
7_I88_L0.8791.00
115_G118_Y0.8771.00
103_E106_R0.8721.00
4_N65_W0.8581.00
6_H82_F0.8571.00
23_S66_I0.8541.00
127_W132_D0.8491.00
113_A119_E0.8481.00
124_F127_W0.8461.00
103_E108_G0.8461.00
23_S29_T0.8461.00
39_L50_E0.8461.00
16_S68_S0.8391.00
49_P53_K0.8381.00
9_G13_V0.8361.00
127_W130_L0.8351.00
46_R51_R0.8271.00
36_Y54_L0.8151.00
103_E109_N0.8141.00
39_L61_I0.7971.00
37_Y45_K0.7881.00
23_S26_L0.7790.99
117_K121_S0.7730.99
113_A120_Q0.7670.99
8_L87_F0.7650.99
19_G30_H0.7640.99
125_L128_A0.7640.99
128_A131_Y0.7570.99
40_D53_K0.7530.99
92_Q115_G0.7500.99
121_S124_F0.7500.99
7_I18_L0.7480.99
7_I86_V0.7450.99
18_L21_A0.7410.99
111_V118_Y0.7380.99
7_I66_I0.7240.99
56_E77_N0.7200.99
39_L46_R0.7200.99
81_Y137_E0.7090.99
121_S127_W0.7020.99
44_K47_E0.6970.99
53_K57_K0.6900.99
89_W129_S0.6850.99
31_L36_Y0.6850.99
127_W131_Y0.6820.99
114_G120_Q0.6810.99
115_G119_E0.6780.99
11_S127_W0.6730.98
35_N39_L0.6640.98
93_D115_G0.6620.98
16_S30_H0.6620.98
110_E114_G0.6610.98
33_T55_L0.6610.98
58_D64_K0.6600.98
57_K60_T0.6590.98
111_V114_G0.6570.98
37_Y55_L0.6560.98
112_L115_G0.6560.98
62_N81_Y0.6520.98
112_L119_E0.6480.98
18_L98_R0.6450.98
17_T98_R0.6360.98
112_L117_K0.6360.98
13_V88_L0.6350.98
52_R73_G0.6320.98
4_N81_Y0.6280.98
37_Y46_R0.6270.98
24_K27_P0.6270.98
132_D136_M0.6250.98
133_N136_M0.6200.97
131_Y137_E0.6180.97
10_A121_S0.6170.97
6_H85_V0.6120.97
127_W133_N0.6110.97
96_L114_G0.6110.97
34_D102_R0.6110.97
131_Y134_A0.6050.97
36_Y46_R0.6010.97
30_H35_N0.6000.97
16_S38_W0.5980.97
38_W102_R0.5980.97
33_T71_V0.5950.97
114_G118_Y0.5940.97
33_T67_L0.5930.97
29_T64_K0.5920.97
129_S133_N0.5850.96
100_R108_G0.5820.96
45_K51_R0.5810.96
121_S128_A0.5800.96
15_T68_S0.5800.96
104_F107_Y0.5790.96
92_Q132_D0.5790.96
103_E107_Y0.5770.96
92_Q96_L0.5660.96
52_R55_L0.5630.96
7_I23_S0.5600.95
100_R110_E0.5590.95
17_T68_S0.5530.95
114_G117_K0.5530.95
128_A134_A0.5480.95
99_L103_E0.5450.95
96_L129_S0.5440.95
5_I82_F0.5410.94
132_D135_G0.5380.94
29_T80_S0.5350.94
28_H58_D0.5290.94
37_Y71_V0.5280.94
39_L58_D0.5260.94
113_A117_K0.5190.93
94_I98_R0.5180.93
26_L64_K0.5150.93
112_L120_Q0.5040.92
14_G98_R0.5020.92
134_A137_E0.5010.92
40_D58_D0.5000.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4qbgB 1 0.9494 99.9 0.457 Contact Map
3gmtA 1 0.8483 99.9 0.466 Contact Map
2xb4A 4 0.9438 99.9 0.469 Contact Map
1zakA 2 1 99.9 0.472 Contact Map
3be4A 1 0.9438 99.9 0.475 Contact Map
1zd8A 1 0.9494 99.9 0.477 Contact Map
4pzlA 2 0.9663 99.9 0.478 Contact Map
1ak2A 1 0.9607 99.9 0.478 Contact Map
4jzkA 1 0.9438 99.9 0.478 Contact Map
4nu0A 1 0.9494 99.9 0.48 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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