GREMLIN Database
YQAB - Uncharacterized protein YqaB
UniProt: P45899 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 172 (154)
Sequences: 193 (163)
Seq/√Len: 13.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
97_Y101_Q3.9621.00
71_Y139_S3.7800.99
85_G98_L3.0680.97
87_K98_L2.9740.96
5_N10_D2.9620.96
108_H150_Y2.7810.95
108_H113_T2.2400.85
40_L106_T2.0550.80
109_F149_I2.0340.79
6_S153_K2.0070.78
15_L36_L1.9940.78
24_P115_M1.9490.76
13_E114_C1.9470.76
16_Y109_F1.9380.76
113_T150_Y1.8950.74
61_D69_Q1.8770.73
138_V143_A1.8410.72
74_A109_F1.8120.71
149_I153_K1.8080.70
76_E99_D1.7580.68
70_W74_A1.7360.67
114_C143_A1.7290.67
16_Y82_R1.6950.65
125_Q151_Y1.6570.63
90_M147_L1.6000.61
58_I135_L1.5620.59
28_N33_A1.5470.58
101_Q108_H1.5450.58
99_D102_S1.5270.57
79_H99_D1.5040.56
33_A93_T1.4900.55
82_R101_Q1.4710.54
122_P128_A1.4680.54
101_Q109_F1.4620.53
80_I93_T1.4570.53
94_W97_Y1.4560.53
42_F94_W1.4410.52
87_K99_D1.4280.52
42_F121_L1.4190.51
74_A108_H1.4140.51
82_R109_F1.4040.50
38_I103_N1.4030.50
5_N13_E1.3970.50
80_I116_L1.3860.49
78_C105_F1.3810.49
113_T142_F1.3350.47
83_H87_K1.3290.46
20_D35_A1.3160.46
70_W142_F1.3100.45
44_P64_K1.3030.45
40_L60_L1.3000.45
119_I135_L1.2990.45
19_I36_L1.2750.44
70_W109_F1.2620.43
19_I32_I1.2570.43
110_C113_T1.2380.42
3_Y82_R1.2360.42
105_F143_A1.2340.42
44_P62_S1.2160.41
133_A151_Y1.2080.40
105_F109_F1.1980.40
111_I132_V1.1930.39
74_A101_Q1.1870.39
47_S72_D1.1750.39
96_D135_L1.1620.38
67_T137_K1.1580.38
39_R57_N1.1480.37
54_G143_A1.1390.37
107_Y111_I1.1390.37
74_A150_Y1.1300.36
128_A143_A1.1170.36
49_A80_I1.1100.35
107_Y142_F1.1030.35
110_C114_C1.0970.35
101_Q116_L1.0820.34
8_L16_Y1.0740.34
44_P63_R1.0700.33
74_A110_C1.0660.33
50_L78_C1.0660.33
40_L71_Y1.0390.32
87_K94_W1.0310.32
68_E118_N1.0230.31
60_L156_Q1.0220.31
4_T7_H1.0160.31
132_V143_A1.0030.30
27_I64_K1.0020.30
20_D81_Y0.9930.30
122_P131_N0.9870.30
62_S145_K0.9860.30
105_F115_M0.9790.29
74_A113_T0.9760.29
110_C142_F0.9760.29
50_L72_D0.9730.29
58_I99_D0.9720.29
11_W82_R0.9580.28
139_S142_F0.9560.28
94_W105_F0.9530.28
4_T65_S0.9530.28
94_W98_L0.9500.28
138_V142_F0.9410.28
114_C120_N0.9220.27
111_I118_N0.8990.26
53_S86_D0.8880.26
10_D147_L0.8790.25
16_Y32_I0.8770.25
46_T60_L0.8700.25
76_E79_H0.8640.25
9_E26_Q0.8620.25
86_D117_R0.8620.25
54_G138_V0.8590.24
39_R55_I0.8570.24
17_K151_Y0.8550.24
125_Q148_S0.8530.24
36_L77_F0.8300.23
92_A134_W0.8300.23
101_Q149_I0.8250.23
82_R91_P0.8200.23
150_Y153_K0.8110.23
14_N26_Q0.8000.22
14_N33_A0.7940.22
10_D38_I0.7920.22
117_R150_Y0.7810.22
8_L109_F0.7740.21
8_L61_D0.7740.21
74_A106_T0.7730.21
17_K28_N0.7730.21
109_F113_T0.7700.21
101_Q145_K0.7630.21
59_C72_D0.7610.21
11_W137_K0.7590.21
16_Y73_F0.7580.21
15_L26_Q0.7530.21
76_E105_F0.7380.20
33_A90_M0.7350.20
75_H87_K0.7310.20
48_F125_Q0.7300.20
29_F70_W0.7290.20
109_F150_Y0.7260.20
33_A86_D0.7210.19
41_S59_C0.7110.19
108_H149_I0.7030.19
11_W78_C0.7020.19
49_A56_Y0.7010.19
52_H60_L0.6910.19
50_L57_N0.6860.18
95_T138_V0.6860.18
114_C119_I0.6830.18
128_A133_A0.6800.18
58_I83_H0.6790.18
6_S45_V0.6780.18
37_D81_Y0.6760.18
103_N134_W0.6690.18
70_W132_V0.6680.18
30_E42_F0.6670.18
96_D116_L0.6670.18
79_H83_H0.6650.18
23_E144_K0.6500.17
11_W36_L0.6490.17
16_Y33_A0.6460.17
37_D117_R0.6430.17
11_W15_L0.6400.17
37_D47_S0.6370.17
112_P146_R0.6340.17
73_F83_H0.6300.17
29_F50_L0.6270.17
97_Y145_K0.6250.17
78_C133_A0.6250.17
32_I55_I0.6230.16
19_I44_P0.6220.16
111_I116_L0.6180.16
47_S60_L0.6180.16
12_I130_E0.6180.16
91_P96_D0.6050.16
76_E87_K0.6030.16
28_N44_P0.6010.16
14_N95_T0.5990.16
58_I76_E0.5980.16
53_S115_M0.5970.16
8_L78_C0.5970.16
83_H101_Q0.5960.16
57_N84_E0.5960.16
18_K41_S0.5930.16
121_L128_A0.5930.16
112_P136_F0.5900.16
104_Y153_K0.5840.15
78_C132_V0.5830.15
12_I75_H0.5770.15
24_P138_V0.5720.15
82_R105_F0.5720.15
42_F68_E0.5710.15
48_F153_K0.5700.15
41_S57_N0.5690.15
55_I144_K0.5640.15
78_C82_R0.5590.15
34_E53_S0.5550.15
102_S155_T0.5540.15
26_Q154_L0.5530.15
77_F149_I0.5460.14
108_H142_F0.5450.14
84_E128_A0.5450.14
128_A152_R0.5420.14
11_W95_T0.5400.14
12_I16_Y0.5400.14
8_L82_R0.5390.14
5_N78_C0.5390.14
148_S152_R0.5380.14
126_S130_E0.5350.14
69_Q72_D0.5330.14
79_H102_S0.5320.14
9_E146_R0.5310.14
152_R157_H0.5270.14
71_Y98_L0.5260.14
33_A73_F0.5250.14
46_T53_S0.5250.14
70_W110_C0.5240.14
12_I116_L0.5230.14
92_A125_Q0.5210.14
32_I141_S0.5210.14
50_L68_E0.5210.14
82_R97_Y0.5200.14
59_C86_D0.5160.14
60_L77_F0.5160.14
79_H112_P0.5150.14
120_N129_I0.5130.14
48_F88_K0.5130.14
97_Y150_Y0.5100.13
18_K64_K0.5100.13
8_L128_A0.5070.13
107_Y115_M0.5060.13
6_S73_F0.5060.13
12_I103_N0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3dteA 2 0.9884 99.7 0.699 Contact Map
4il3A 1 0.8605 93.1 0.906 Contact Map
4aw6A 2 0.8198 92.9 0.907 Contact Map
3cqbA 4 0.4651 78.4 0.926 Contact Map
3c37A 1 0.8488 68.8 0.931 Contact Map
4jixA 2 0.5756 63.7 0.933 Contact Map
4qhjA 2 0.5581 54.7 0.937 Contact Map
4jiuA 1 0.564 50.6 0.939 Contact Map
4in9A 1 0.6686 30.1 0.946 Contact Map
4dv8A 1 0.9128 23.8 0.949 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0141 seconds.