GREMLIN Database
MAO2 - Probable NAD-dependent malic enzyme 2
UniProt: P45868 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 582 (537)
Sequences: 1481 (836)
Seq/√Len: 36.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
419_E423_K8.5621.00
222_E226_N6.0071.00
241_E245_A4.2151.00
82_F117_M4.1181.00
154_E256_K4.1141.00
110_L121_V4.0841.00
332_D375_Y4.0641.00
506_A553_D3.9941.00
168_D209_R3.9011.00
426_A455_T3.7551.00
172_A250_Y3.7491.00
504_T555_V3.6741.00
244_E275_N3.5371.00
422_V454_W3.3651.00
319_V398_V3.2671.00
449_E453_K3.1981.00
108_K112_N3.1141.00
394_P397_E3.0901.00
363_E378_N3.0391.00
151_D249_A2.9951.00
220_N239_Q2.9631.00
128_E132_E2.9601.00
426_A458_K2.8901.00
281_N505_P2.8721.00
215_L247_I2.8281.00
456_D473_N2.8241.00
248_D283_E2.7911.00
222_E236_E2.7131.00
396_D420_E2.6941.00
265_W286_T2.6801.00
423_K456_D2.6721.00
400_R424_E2.6241.00
446_A451_L2.6121.00
78_A109_L2.5871.00
251_V284_I2.5841.00
424_E428_H2.4361.00
495_S503_I2.4231.00
46_K54_E2.3861.00
85_Q90_R2.3501.00
544_I567_V2.3240.99
344_S347_E2.3150.99
504_T553_D2.3110.99
549_A553_D2.3030.99
540_I568_L2.2990.99
250_Y254_A2.2950.99
158_E257_F2.2060.99
396_D421_I2.2040.99
424_E427_S2.1940.99
357_Y372_Q2.1700.99
83_Q116_E2.1660.99
521_L525_G2.1620.99
295_G333_Q2.1590.99
88_R91_Q2.0970.99
321_F416_A2.0800.99
549_A552_K2.0530.99
343_L351_R2.0530.99
113_H116_E2.0250.99
452_F472_Y2.0190.99
425_M434_I2.0110.98
56_Q61_E2.0110.98
312_S315_D1.9860.98
79_Y113_H1.9710.98
422_V434_I1.9510.98
103_E141_Q1.9510.98
487_A491_L1.9470.98
490_G494_G1.9440.98
430_D458_K1.9180.98
145_L153_I1.8860.98
71_L108_K1.8690.98
70_S73_Q1.8560.97
272_N275_N1.8530.97
147_I238_V1.8300.97
302_V334_I1.8260.97
330_I410_T1.8240.97
447_V450_D1.8230.97
87_D90_R1.8210.97
564_K568_L1.8160.97
460_L528_L1.8100.97
507_M550_A1.8090.97
248_D279_K1.8040.97
123_T465_S1.7640.96
321_F413_V1.7420.96
302_V406_I1.7400.96
148_D233_N1.7370.96
368_I376_L1.7110.96
314_K341_A1.7010.96
399_V421_I1.6740.95
340_L513_D1.6730.95
260_K499_E1.6590.95
248_D252_K1.6360.95
251_V263_L1.6300.94
301_G529_L1.6240.94
75_A108_K1.6190.94
285_L495_S1.6180.94
565_Q569_D1.6170.94
225_L236_E1.6140.94
347_E351_R1.6070.94
172_A254_A1.5930.94
419_E454_W1.5840.94
471_E476_S1.5830.94
153_I246_F1.5700.93
115_R533_D1.5640.93
251_V265_W1.5640.93
147_I246_F1.5620.93
396_D400_R1.5560.93
221_N224_L1.5500.93
79_Y83_Q1.5490.93
345_E349_N1.5410.93
403_K428_H1.5370.92
316_Q405_T1.5370.92
335_R349_N1.5250.92
377_R381_E1.5250.92
176_E220_N1.5240.92
562_D565_Q1.5200.92
534_K537_E1.5140.92
319_V355_L1.5140.92
244_E272_N1.5130.92
170_I254_A1.5040.92
213_V250_Y1.4900.91
75_A112_N1.4890.91
319_V402_A1.4870.91
176_E269_G1.4770.91
504_T507_M1.4640.91
177_S181_I1.4610.90
318_V338_M1.4610.90
263_L284_I1.4560.90
79_Y117_M1.4540.90
471_E474_G1.4520.90
69_L77_R1.4500.90
176_E272_N1.4460.90
548_E552_K1.4350.90
169_L492_G1.4350.90
135_H227_D1.4340.90
504_T549_A1.4330.90
61_E149_N1.4320.90
147_I233_N1.4240.89
494_G550_A1.4210.89
422_V455_T1.4180.89
247_I276_I1.4170.89
482_S529_L1.4110.89
540_I564_K1.4080.89
494_G498_A1.4060.89
71_L104_V1.4040.89
82_F120_V1.3930.88
544_I564_K1.3850.88
497_V547_A1.3830.88
358_R372_Q1.3730.87
434_I451_L1.3710.87
400_R420_E1.3680.87
352_F377_R1.3660.87
48_V231_I1.3640.87
494_G500_A1.3570.87
448_P461_I1.3350.86
548_E560_P1.3330.86
419_E456_D1.3320.86
452_F479_I1.3190.85
235_H238_V1.3130.85
189_I214_V1.3030.84
320_I331_A1.2910.84
472_Y477_Y1.2900.84
494_G546_V1.2880.84
305_A433_V1.2850.84
79_Y116_E1.2830.84
148_D235_H1.2700.83
412_G416_A1.2690.83
446_A461_I1.2670.83
361_L372_Q1.2640.83
150_I242_R1.2490.82
262_L503_I1.2460.82
396_D424_E1.2440.82
541_Q564_K1.2390.81
498_A547_A1.2390.81
213_V246_F1.2390.81
79_Y109_L1.2380.81
549_A555_V1.2280.81
450_D453_K1.2270.81
357_Y361_L1.2230.80
302_V318_V1.2200.80
102_N576_Y1.2140.80
297_I515_I1.2070.80
423_K458_K1.1980.79
130_I181_I1.1980.79
377_R402_A1.1960.79
255_L284_I1.1890.79
456_D472_Y1.1820.78
241_E244_E1.1790.78
350_K378_N1.1750.78
415_G450_D1.1710.77
35_G38_V1.1700.77
338_M343_L1.1700.77
422_V451_L1.1690.77
452_F477_Y1.1580.77
142_G189_I1.1570.77
520_D524_P1.1550.76
38_V58_L1.1550.76
123_T127_G1.1540.76
403_K427_S1.1530.76
500_A507_M1.1530.76
215_L246_F1.1510.76
355_L395_F1.1460.76
96_S106_F1.1430.76
133_Y193_I1.1390.75
205_I493_L1.1360.75
127_G488_F1.1330.75
173_T214_V1.1220.74
421_I424_E1.1170.74
130_I178_I1.1150.74
128_E131_Q1.1100.74
111_K536_Q1.1090.73
78_A94_Y1.1080.73
274_R372_Q1.1020.73
150_I249_A1.1020.73
353_Y402_A1.1000.73
123_T488_F1.0960.73
153_I157_F1.0910.72
98_L126_V1.0860.72
99_A141_Q1.0850.72
154_E257_F1.0780.71
301_G435_M1.0730.71
301_G480_G1.0730.71
355_L398_V1.0730.71
53_E57_E1.0730.71
89_L136_E1.0710.71
317_R405_T1.0700.71
317_R402_A1.0670.71
154_E249_A1.0660.70
297_I542_V1.0640.70
395_F407_L1.0610.70
145_L157_F1.0610.70
254_A261_A1.0600.70
452_F457_G1.0590.70
248_D280_Y1.0530.70
150_I245_A1.0510.69
205_I496_I1.0400.69
517_E545_A1.0360.68
255_L263_L1.0270.68
363_E376_L1.0270.68
252_K283_E1.0260.67
510_A545_A1.0230.67
397_E401_Q1.0190.67
202_A410_T1.0190.67
72_D473_N1.0170.67
364_D379_A1.0150.67
338_M351_R1.0070.66
469_N478_E1.0060.66
282_H502_I1.0050.66
38_V60_L1.0020.66
45_N50_F0.9950.65
100_N139_R0.9950.65
487_A515_I0.9920.65
239_Q272_N0.9900.65
175_S214_V0.9880.65
270_N325_S0.9870.64
332_D374_P0.9850.64
397_E400_R0.9830.64
130_I177_S0.9800.64
157_F257_F0.9790.64
130_I190_N0.9780.64
253_A257_F0.9740.63
446_A463_T0.9700.63
67_T234_K0.9690.63
181_I184_W0.9590.62
559_Q563_V0.9560.62
540_I571_M0.9520.62
269_G325_S0.9520.62
365_I372_Q0.9490.61
491_L508_F0.9480.61
46_K577_K0.9480.61
540_I544_I0.9480.61
123_T467_F0.9350.60
515_I542_V0.9340.60
455_T538_V0.9340.60
339_V345_E0.9320.60
83_Q113_H0.9300.60
97_D101_R0.9280.60
347_E350_K0.9270.60
352_F398_V0.9240.59
220_N236_E0.9230.59
361_L376_L0.9200.59
99_A103_E0.9190.59
33_L38_V0.9190.59
514_A541_Q0.9170.59
109_L117_M0.9160.59
154_E158_E0.9150.58
420_E424_E0.9150.58
126_V194_G0.9150.58
147_I153_I0.9150.58
222_E225_L0.9070.58
176_E239_Q0.9060.58
96_S99_A0.9060.58
67_T73_Q0.9050.58
225_L234_K0.9050.58
194_G201_A0.9040.58
64_L68_V0.9030.57
169_L199_Y0.9030.57
423_K455_T0.9000.57
100_N141_Q0.8990.57
203_A269_G0.8940.57
93_V138_R0.8940.57
335_R339_V0.8920.57
499_E557_N0.8890.56
298_T361_L0.8890.56
123_T297_I0.8870.56
328_I354_T0.8850.56
128_E442_H0.8840.56
358_R361_L0.8820.56
536_Q571_M0.8780.55
49_A576_Y0.8760.55
363_E379_A0.8760.55
86_P90_R0.8760.55
171_V264_H0.8740.55
166_D209_R0.8720.55
419_E455_T0.8710.55
532_I542_V0.8700.55
85_Q93_V0.8690.55
177_S190_N0.8640.54
451_L461_I0.8630.54
463_T479_I0.8620.54
315_D347_E0.8560.53
220_N223_K0.8550.53
134_S225_L0.8530.53
87_D128_E0.8530.53
140_P435_M0.8520.53
448_P463_T0.8520.53
497_V566_A0.8500.53
321_F395_F0.8390.52
499_E558_R0.8390.52
47_G139_R0.8390.52
265_W284_I0.8370.52
126_V189_I0.8350.52
393_I398_V0.8280.51
426_A429_V0.8280.51
145_L156_A0.8270.51
245_A420_E0.8260.51
563_V567_V0.8240.51
336_D345_E0.8220.50
153_I249_A0.8210.50
213_V254_A0.8210.50
93_V136_E0.8200.50
551_I560_P0.8200.50
130_I486_F0.8180.50
98_L101_R0.8170.50
247_I286_T0.8120.50
186_V247_I0.8120.50
419_E422_V0.8100.49
441_T466_P0.8090.49
446_A572_W0.8090.49
77_R462_A0.8070.49
206_D209_R0.8060.49
313_I338_M0.8050.49
480_G529_L0.8040.49
319_V421_I0.8040.49
194_G199_Y0.7970.48
404_P425_M0.7950.48
196_L480_G0.7900.48
149_N152_G0.7900.48
139_R431_R0.7890.48
475_V526_A0.7890.48
33_L41_I0.7890.48
274_R375_Y0.7890.48
193_I339_V0.7880.48
418_T421_I0.7860.47
559_Q562_D0.7850.47
48_V574_P0.7850.47
357_Y412_G0.7850.47
436_P454_W0.7840.47
404_P428_H0.7820.47
502_I555_V0.7820.47
131_Q442_H0.7810.47
63_L159_N0.7810.47
314_K343_L0.7800.47
346_E350_K0.7800.47
506_A549_A0.7780.47
522_E525_G0.7780.47
214_V361_L0.7770.47
177_S486_F0.7720.46
69_L101_R0.7720.46
547_A551_I0.7700.46
176_E410_T0.7690.46
320_I408_I0.7680.46
274_R371_F0.7660.46
177_S192_A0.7660.46
327_G528_L0.7640.45
398_V402_A0.7620.45
353_Y377_R0.7610.45
69_L94_Y0.7560.45
566_A570_A0.7550.45
433_V462_A0.7540.45
93_V542_V0.7530.44
186_V231_I0.7520.44
262_L285_L0.7520.44
298_T482_S0.7510.44
219_T225_L0.7500.44
444_A467_F0.7470.44
437_M467_F0.7470.44
194_G481_Q0.7460.44
130_I295_G0.7460.44
318_V334_I0.7450.44
535_L542_V0.7430.44
181_I190_N0.7420.44
550_A555_V0.7370.43
50_F54_E0.7360.43
34_R59_G0.7360.43
311_A316_Q0.7340.43
135_H229_L0.7330.43
317_R404_P0.7330.43
419_E453_K0.7320.43
501_R557_N0.7320.43
287_F466_P0.7310.43
307_K517_E0.7290.42
357_Y413_V0.7290.42
362_T379_A0.7280.42
46_K50_F0.7260.42
143_I160_L0.7230.42
238_V246_F0.7230.42
103_E295_G0.7220.42
480_G519_V0.7220.42
362_T382_V0.7200.42
68_V459_V0.7200.42
357_Y365_I0.7200.42
80_E83_Q0.7200.42
154_E253_A0.7190.42
80_E135_H0.7180.42
167_I257_F0.7180.42
61_E152_G0.7180.42
514_A518_M0.7120.41
565_Q568_L0.7120.41
493_L571_M0.7100.41
352_F405_T0.7090.41
411_S416_A0.7090.41
497_V570_A0.7060.40
92_N333_Q0.7040.40
287_F465_S0.7040.40
451_L463_T0.7030.40
176_E485_A0.7020.40
198_V264_H0.7010.40
126_V181_I0.7010.40
75_A109_L0.6990.40
518_M541_Q0.6990.40
523_T534_K0.6970.40
514_A542_V0.6970.40
123_T291_I0.6960.40
60_L64_L0.6960.40
265_W486_F0.6950.40
339_V343_L0.6940.39
202_A532_I0.6930.39
51_S54_E0.6930.39
269_G272_N0.6920.39
308_K431_R0.6910.39
485_A567_V0.6910.39
270_N372_Q0.6900.39
441_T469_N0.6880.39
370_D373_K0.6880.39
85_Q94_Y0.6880.39
259_P574_P0.6860.39
244_E247_I0.6860.39
242_R245_A0.6850.39
336_D339_V0.6840.39
556_A559_Q0.6820.38
338_M342_G0.6820.38
358_R365_I0.6820.38
146_S246_F0.6810.38
274_R291_I0.6810.38
130_I192_A0.6810.38
147_I150_I0.6800.38
551_I556_A0.6800.38
396_D399_V0.6790.38
134_S187_G0.6790.38
264_H482_S0.6780.38
467_F488_F0.6770.38
243_Y269_G0.6750.38
306_M312_S0.6750.38
181_I410_T0.6740.38
518_M534_K0.6730.38
245_A249_A0.6730.38
115_R531_S0.6720.38
312_S341_A0.6700.38
123_T412_G0.6690.37
225_L469_N0.6680.37
535_L539_S0.6680.37
242_R350_K0.6670.37
306_M311_A0.6670.37
176_E243_Y0.6660.37
198_V286_T0.6640.37
104_V327_G0.6640.37
327_G410_T0.6640.37
274_R325_S0.6630.37
500_A503_I0.6630.37
423_K454_W0.6630.37
107_Y434_I0.6630.37
68_V87_D0.6620.37
302_V306_M0.6610.37
269_G485_A0.6610.37
256_K423_K0.6600.37
524_P527_G0.6600.37
265_W276_I0.6590.37
130_I410_T0.6590.37
85_Q485_A0.6580.37
221_N226_N0.6580.37
513_D517_E0.6580.37
319_V377_R0.6570.36
410_T486_F0.6540.36
169_L262_L0.6540.36
48_V69_L0.6540.36
538_V542_V0.6540.36
520_D523_T0.6520.36
158_E234_K0.6470.36
451_L572_W0.6460.36
428_H455_T0.6460.36
130_I175_S0.6460.36
108_K575_E0.6430.35
181_I486_F0.6430.35
285_L295_G0.6420.35
455_T459_V0.6420.35
94_Y137_Y0.6420.35
540_I567_V0.6410.35
129_A142_G0.6400.35
141_Q285_L0.6380.35
213_V247_I0.6380.35
72_D112_N0.6370.35
225_L235_H0.6360.35
262_L491_L0.6360.35
240_G243_Y0.6360.35
54_E74_Q0.6350.35
342_G348_A0.6350.35
91_Q116_E0.6340.35
500_A546_V0.6340.35
533_D552_K0.6330.35
350_K399_V0.6330.35
295_G410_T0.6310.34
394_P398_V0.6310.34
461_I470_V0.6290.34
202_A330_I0.6290.34
548_E551_I0.6280.34
321_F355_L0.6280.34
323_A354_T0.6260.34
89_L93_V0.6240.34
504_T550_A0.6240.34
132_E135_H0.6230.34
107_Y278_K0.6230.34
336_D349_N0.6220.34
103_E138_R0.6210.34
469_N476_S0.6200.34
169_L198_V0.6200.34
446_A450_D0.6190.33
130_I184_W0.6190.33
189_I192_A0.6190.33
426_A430_D0.6180.33
106_F110_L0.6180.33
106_F504_T0.6170.33
500_A555_V0.6170.33
74_Q105_L0.6170.33
129_A462_A0.6160.33
88_R128_E0.6160.33
161_H249_A0.6160.33
190_N487_A0.6160.33
521_L524_P0.6140.33
419_E450_D0.6130.33
91_Q120_V0.6120.33
240_G272_N0.6110.33
447_V461_I0.6110.33
370_D411_S0.6100.33
145_L155_K0.6100.33
197_A542_V0.6100.33
49_A70_S0.6100.33
152_G155_K0.6080.33
302_V435_M0.6080.33
191_I439_N0.6070.33
39_L64_L0.6070.33
412_G443_L0.6070.33
407_L490_G0.6060.32
177_S198_V0.6060.32
244_E248_D0.6060.32
127_G173_T0.6040.32
332_D349_N0.6040.32
95_L342_G0.6040.32
372_Q529_L0.6040.32
418_T450_D0.6030.32
403_K451_L0.6020.32
177_S410_T0.6020.32
34_R38_V0.6000.32
536_Q573_T0.6000.32
354_T361_L0.6000.32
217_V243_Y0.6000.32
92_N295_G0.5990.32
261_A276_I0.5990.32
126_V264_H0.5980.32
264_H486_F0.5980.32
326_A439_N0.5970.32
399_V449_E0.5970.32
344_S350_K0.5970.32
414_S450_D0.5960.32
264_H287_F0.5960.32
161_H164_A0.5960.32
123_T442_H0.5960.32
48_V98_L0.5940.32
71_L75_A0.5940.32
426_A456_D0.5930.31
465_S539_S0.5930.31
350_K377_R0.5930.31
169_L181_I0.5920.31
469_N502_I0.5920.31
55_R64_L0.5920.31
82_F109_L0.5910.31
181_I192_A0.5910.31
424_E429_V0.5900.31
490_G550_A0.5900.31
475_V525_G0.5890.31
144_Y168_D0.5890.31
298_T437_M0.5890.31
507_M553_D0.5890.31
405_T429_V0.5880.31
403_K501_R0.5880.31
414_S418_T0.5880.31
446_A479_I0.5850.31
133_Y330_I0.5850.31
486_F542_V0.5850.31
147_I567_V0.5840.31
422_V450_D0.5840.31
133_Y197_A0.5840.31
333_Q508_F0.5840.31
198_V265_W0.5840.31
335_R376_L0.5830.31
436_P452_F0.5830.31
210_V264_H0.5820.31
308_K521_L0.5820.31
520_D525_G0.5820.31
130_I264_H0.5820.31
49_A74_Q0.5810.31
444_A447_V0.5810.31
308_K460_L0.5800.30
545_A548_E0.5800.30
74_Q102_N0.5800.30
37_E41_I0.5790.30
436_P542_V0.5780.30
146_S149_N0.5770.30
130_I169_L0.5760.30
439_N466_P0.5750.30
291_I325_S0.5750.30
355_L421_I0.5750.30
412_G437_M0.5750.30
41_I56_Q0.5740.30
339_V565_Q0.5740.30
274_R332_D0.5720.30
52_L56_Q0.5720.30
303_L513_D0.5710.30
106_F197_A0.5710.30
73_Q234_K0.5710.30
556_A560_P0.5700.30
350_K453_K0.5700.30
85_Q97_D0.5700.30
155_K475_V0.5690.30
176_E529_L0.5680.30
347_E449_E0.5680.30
444_A451_L0.5670.30
448_P467_F0.5670.30
318_V406_I0.5660.29
150_I253_A0.5660.29
272_N333_Q0.5660.29
265_W396_D0.5650.29
172_A221_N0.5650.29
122_Y191_I0.5640.29
100_N138_R0.5640.29
294_T484_N0.5640.29
394_P421_I0.5640.29
196_L210_V0.5640.29
201_A482_S0.5640.29
194_G482_S0.5640.29
104_V576_Y0.5630.29
544_I548_E0.5620.29
458_K552_K0.5620.29
437_M444_A0.5610.29
117_M120_V0.5600.29
151_D215_L0.5600.29
311_A405_T0.5590.29
532_I535_L0.5570.29
330_I485_A0.5560.29
358_R413_V0.5560.29
465_S488_F0.5560.29
237_R243_Y0.5560.29
176_E330_I0.5550.29
42_P45_N0.5550.29
406_I433_V0.5540.29
107_Y193_I0.5540.29
507_M542_V0.5540.29
186_V508_F0.5530.29
77_R317_R0.5520.28
379_A382_V0.5500.28
77_R229_L0.5500.28
76_Q80_E0.5490.28
503_I546_V0.5490.28
200_T469_N0.5480.28
510_A549_A0.5480.28
41_I44_L0.5480.28
514_A517_E0.5480.28
310_G423_K0.5470.28
215_L311_A0.5470.28
73_Q90_R0.5470.28
177_S270_N0.5440.28
114_L575_E0.5440.28
102_N105_L0.5440.28
132_E435_M0.5430.28
439_N484_N0.5430.28
278_K282_H0.5420.28
239_Q242_R0.5420.28
265_W323_A0.5420.28
546_V550_A0.5420.28
515_I545_A0.5420.28
486_F532_I0.5400.28
321_F412_G0.5390.28
134_S491_L0.5390.28
344_S449_E0.5390.28
336_D505_P0.5380.27
62_G159_N0.5370.27
152_G453_K0.5370.27
532_I539_S0.5370.27
117_M515_I0.5360.27
481_Q484_N0.5360.27
48_V59_G0.5360.27
134_S508_F0.5350.27
133_Y189_I0.5350.27
69_L133_Y0.5350.27
221_N357_Y0.5350.27
132_E283_E0.5340.27
268_L466_P0.5340.27
497_V567_V0.5340.27
270_N369_L0.5340.27
495_S498_A0.5340.27
142_G467_F0.5330.27
299_L337_T0.5330.27
452_F459_V0.5330.27
203_A482_S0.5320.27
551_I563_V0.5310.27
72_D537_E0.5310.27
72_D260_K0.5310.27
192_A214_V0.5310.27
301_G308_K0.5300.27
265_W320_I0.5300.27
361_L506_A0.5290.27
306_M309_T0.5290.27
144_Y542_V0.5290.27
444_A465_S0.5290.27
552_K555_V0.5280.27
131_Q488_F0.5280.27
112_N116_E0.5270.27
34_R58_L0.5270.27
149_N257_F0.5270.27
143_I151_D0.5260.27
551_I558_R0.5260.27
107_Y501_R0.5260.27
198_V486_F0.5250.27
76_Q87_D0.5240.27
337_T341_A0.5220.26
339_V348_A0.5210.26
446_A454_W0.5210.26
56_Q155_K0.5200.26
243_Y272_N0.5200.26
367_G490_G0.5190.26
395_F398_V0.5180.26
123_T439_N0.5170.26
507_M549_A0.5170.26
482_S524_P0.5170.26
104_V258_F0.5170.26
304_A528_L0.5160.26
69_L81_Q0.5160.26
148_D242_R0.5150.26
133_Y299_L0.5150.26
76_Q228_P0.5130.26
370_D421_I0.5130.26
203_A333_Q0.5130.26
339_V342_G0.5130.26
276_I486_F0.5130.26
514_A543_A0.5130.26
107_Y241_E0.5120.26
281_N435_M0.5120.26
373_K561_E0.5120.26
279_K319_V0.5110.26
518_M538_V0.5110.26
452_F470_V0.5100.26
356_D365_I0.5090.26
123_T287_F0.5090.26
310_G350_K0.5090.26
220_N333_Q0.5080.25
93_V235_H0.5080.25
500_A547_A0.5080.25
34_R37_E0.5080.25
100_N398_V0.5080.25
52_L61_E0.5080.25
309_T312_S0.5070.25
123_T466_P0.5060.25
269_G275_N0.5050.25
192_A196_L0.5050.25
248_D255_L0.5050.25
508_F511_T0.5040.25
147_I215_L0.5040.25
265_W354_T0.5040.25
272_N485_A0.5040.25
442_H465_S0.5030.25
281_N418_T0.5030.25
422_V459_V0.5020.25
436_P446_A0.5020.25
160_L572_W0.5020.25
83_Q117_M0.5020.25
347_E453_K0.5010.25
143_I213_V0.5000.25
239_Q265_W0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1o0sA 4 0.9691 100 0.163 Contact Map
1gq2A 6 0.9244 100 0.163 Contact Map
1pj3A 4 0.9313 100 0.167 Contact Map
3nv9A 2 0.7663 100 0.546 Contact Map
1vl6A 4 0.6289 100 0.615 Contact Map
2a9fA 2 0.6478 100 0.669 Contact Map
2dvmA 2 0.7027 100 0.675 Contact Map
4ppmA 2 0.0344 99.4 0.944 Contact Map
1v8bA 4 0.7268 98.9 0.956 Contact Map
3aoeE 3 0.6495 98.5 0.962 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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