MAO2 - BACSU - GREMLIN Contacts

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MAO2 - Probable NAD-dependent malic enzyme 2

UniProt:	P45868	Sequences: MGYYLTWLTISRKKEICLNNIKKTKEGHLETTLRGKEVLSIPTLNKGVAFSLEERQELGLEGLLPPTVLSLDQQAQRAYEQFQAQPDRLRQNVYLSDLANRNEVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYLSIDNIDGIEKAFENLHATAGDIDLIVATDSESILGIGDWGVGGINIAIGKLAVYTAAAGIDPSRVIPVVLDVGTNNEKLLNDPLYIGNKHERVQGERYEAFIDAYVKAALKFFPKALLHWEDLGNKNARNIMKKYNHEILTFNDDIQGTGAITLAGVLAAMKKTGASIKDQRVVIFGAGSAGIGIADQIRDTMVLAGLSEEEANKRFYTLDYRGLLTEDIEGILDFQKPYLRNADEVKDWKRDEKGQIPFDEVVRQAKPTILIGTSGVSGAFTEEIVKEMASHVDRPVIMPMSNPTHLAEAVPEDLFKWTDGKVLIATGSPFDNVEYNGVSYEIGQSNNAFAFPGLGLGSIVAEARIITPAMFAATADAIAEMVDLETPGAGLLPSIDKLQEVSIQVAIAVAEAAIKDGVANRQPEDVKQAVLDAMWTPEYKKVIAK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	582 (537)
Sequences:	1481 (836)
Seq/√Len:	36.1

ECOLI - MAO1
BACSU - MAO2 MAO3 MAO1 MAO4
SULSO - Q97UX2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
419_E	423_K	8.562	1.00
222_E	226_N	6.007	1.00
241_E	245_A	4.215	1.00
82_F	117_M	4.118	1.00
154_E	256_K	4.114	1.00
110_L	121_V	4.084	1.00
332_D	375_Y	4.064	1.00
506_A	553_D	3.994	1.00
168_D	209_R	3.901	1.00
426_A	455_T	3.755	1.00
172_A	250_Y	3.749	1.00
504_T	555_V	3.674	1.00
244_E	275_N	3.537	1.00
422_V	454_W	3.365	1.00
319_V	398_V	3.267	1.00
449_E	453_K	3.198	1.00
108_K	112_N	3.114	1.00
394_P	397_E	3.090	1.00
363_E	378_N	3.039	1.00
151_D	249_A	2.995	1.00
220_N	239_Q	2.963	1.00
128_E	132_E	2.960	1.00
426_A	458_K	2.890	1.00
281_N	505_P	2.872	1.00
215_L	247_I	2.828	1.00
456_D	473_N	2.824	1.00
248_D	283_E	2.791	1.00
222_E	236_E	2.713	1.00
396_D	420_E	2.694	1.00
265_W	286_T	2.680	1.00
423_K	456_D	2.672	1.00
400_R	424_E	2.624	1.00
446_A	451_L	2.612	1.00
78_A	109_L	2.587	1.00
251_V	284_I	2.584	1.00
424_E	428_H	2.436	1.00
495_S	503_I	2.423	1.00
46_K	54_E	2.386	1.00
85_Q	90_R	2.350	1.00
544_I	567_V	2.324	0.99
344_S	347_E	2.315	0.99
504_T	553_D	2.311	0.99
549_A	553_D	2.303	0.99
540_I	568_L	2.299	0.99
250_Y	254_A	2.295	0.99
158_E	257_F	2.206	0.99
396_D	421_I	2.204	0.99
424_E	427_S	2.194	0.99
357_Y	372_Q	2.170	0.99
83_Q	116_E	2.166	0.99
521_L	525_G	2.162	0.99
295_G	333_Q	2.159	0.99
88_R	91_Q	2.097	0.99
321_F	416_A	2.080	0.99
549_A	552_K	2.053	0.99
343_L	351_R	2.053	0.99
113_H	116_E	2.025	0.99
452_F	472_Y	2.019	0.99
425_M	434_I	2.011	0.98
56_Q	61_E	2.011	0.98
312_S	315_D	1.986	0.98
79_Y	113_H	1.971	0.98
422_V	434_I	1.951	0.98
103_E	141_Q	1.951	0.98
487_A	491_L	1.947	0.98
490_G	494_G	1.944	0.98
430_D	458_K	1.918	0.98
145_L	153_I	1.886	0.98
71_L	108_K	1.869	0.98
70_S	73_Q	1.856	0.97
272_N	275_N	1.853	0.97
147_I	238_V	1.830	0.97
302_V	334_I	1.826	0.97
330_I	410_T	1.824	0.97
447_V	450_D	1.823	0.97
87_D	90_R	1.821	0.97
564_K	568_L	1.816	0.97
460_L	528_L	1.810	0.97
507_M	550_A	1.809	0.97
248_D	279_K	1.804	0.97
123_T	465_S	1.764	0.96
321_F	413_V	1.742	0.96
302_V	406_I	1.740	0.96
148_D	233_N	1.737	0.96
368_I	376_L	1.711	0.96
314_K	341_A	1.701	0.96
399_V	421_I	1.674	0.95
340_L	513_D	1.673	0.95
260_K	499_E	1.659	0.95
248_D	252_K	1.636	0.95
251_V	263_L	1.630	0.94
301_G	529_L	1.624	0.94
75_A	108_K	1.619	0.94
285_L	495_S	1.618	0.94
565_Q	569_D	1.617	0.94
225_L	236_E	1.614	0.94
347_E	351_R	1.607	0.94
172_A	254_A	1.593	0.94
419_E	454_W	1.584	0.94
471_E	476_S	1.583	0.94
153_I	246_F	1.570	0.93
115_R	533_D	1.564	0.93
251_V	265_W	1.564	0.93
147_I	246_F	1.562	0.93
396_D	400_R	1.556	0.93
221_N	224_L	1.550	0.93
79_Y	83_Q	1.549	0.93
345_E	349_N	1.541	0.93
403_K	428_H	1.537	0.92
316_Q	405_T	1.537	0.92
335_R	349_N	1.525	0.92
377_R	381_E	1.525	0.92
176_E	220_N	1.524	0.92
562_D	565_Q	1.520	0.92
534_K	537_E	1.514	0.92
319_V	355_L	1.514	0.92
244_E	272_N	1.513	0.92
170_I	254_A	1.504	0.92
213_V	250_Y	1.490	0.91
75_A	112_N	1.489	0.91
319_V	402_A	1.487	0.91
176_E	269_G	1.477	0.91
504_T	507_M	1.464	0.91
177_S	181_I	1.461	0.90
318_V	338_M	1.461	0.90
263_L	284_I	1.456	0.90
79_Y	117_M	1.454	0.90
471_E	474_G	1.452	0.90
69_L	77_R	1.450	0.90
176_E	272_N	1.446	0.90
548_E	552_K	1.435	0.90
169_L	492_G	1.435	0.90
135_H	227_D	1.434	0.90
504_T	549_A	1.433	0.90
61_E	149_N	1.432	0.90
147_I	233_N	1.424	0.89
494_G	550_A	1.421	0.89
422_V	455_T	1.418	0.89
247_I	276_I	1.417	0.89
482_S	529_L	1.411	0.89
540_I	564_K	1.408	0.89
494_G	498_A	1.406	0.89
71_L	104_V	1.404	0.89
82_F	120_V	1.393	0.88
544_I	564_K	1.385	0.88
497_V	547_A	1.383	0.88
358_R	372_Q	1.373	0.87
434_I	451_L	1.371	0.87
400_R	420_E	1.368	0.87
352_F	377_R	1.366	0.87
48_V	231_I	1.364	0.87
494_G	500_A	1.357	0.87
448_P	461_I	1.335	0.86
548_E	560_P	1.333	0.86
419_E	456_D	1.332	0.86
452_F	479_I	1.319	0.85
235_H	238_V	1.313	0.85
189_I	214_V	1.303	0.84
320_I	331_A	1.291	0.84
472_Y	477_Y	1.290	0.84
494_G	546_V	1.288	0.84
305_A	433_V	1.285	0.84
79_Y	116_E	1.283	0.84
148_D	235_H	1.270	0.83
412_G	416_A	1.269	0.83
446_A	461_I	1.267	0.83
361_L	372_Q	1.264	0.83
150_I	242_R	1.249	0.82
262_L	503_I	1.246	0.82
396_D	424_E	1.244	0.82
541_Q	564_K	1.239	0.81
498_A	547_A	1.239	0.81
213_V	246_F	1.239	0.81
79_Y	109_L	1.238	0.81
549_A	555_V	1.228	0.81
450_D	453_K	1.227	0.81
357_Y	361_L	1.223	0.80
302_V	318_V	1.220	0.80
102_N	576_Y	1.214	0.80
297_I	515_I	1.207	0.80
423_K	458_K	1.198	0.79
130_I	181_I	1.198	0.79
377_R	402_A	1.196	0.79
255_L	284_I	1.189	0.79
456_D	472_Y	1.182	0.78
241_E	244_E	1.179	0.78
350_K	378_N	1.175	0.78
415_G	450_D	1.171	0.77
35_G	38_V	1.170	0.77
338_M	343_L	1.170	0.77
422_V	451_L	1.169	0.77
452_F	477_Y	1.158	0.77
142_G	189_I	1.157	0.77
520_D	524_P	1.155	0.76
38_V	58_L	1.155	0.76
123_T	127_G	1.154	0.76
403_K	427_S	1.153	0.76
500_A	507_M	1.153	0.76
215_L	246_F	1.151	0.76
355_L	395_F	1.146	0.76
96_S	106_F	1.143	0.76
133_Y	193_I	1.139	0.75
205_I	493_L	1.136	0.75
127_G	488_F	1.133	0.75
173_T	214_V	1.122	0.74
421_I	424_E	1.117	0.74
130_I	178_I	1.115	0.74
128_E	131_Q	1.110	0.74
111_K	536_Q	1.109	0.73
78_A	94_Y	1.108	0.73
274_R	372_Q	1.102	0.73
150_I	249_A	1.102	0.73
353_Y	402_A	1.100	0.73
123_T	488_F	1.096	0.73
153_I	157_F	1.091	0.72
98_L	126_V	1.086	0.72
99_A	141_Q	1.085	0.72
154_E	257_F	1.078	0.71
301_G	435_M	1.073	0.71
301_G	480_G	1.073	0.71
355_L	398_V	1.073	0.71
53_E	57_E	1.073	0.71
89_L	136_E	1.071	0.71
317_R	405_T	1.070	0.71
317_R	402_A	1.067	0.71
154_E	249_A	1.066	0.70
297_I	542_V	1.064	0.70
395_F	407_L	1.061	0.70
145_L	157_F	1.061	0.70
254_A	261_A	1.060	0.70
452_F	457_G	1.059	0.70
248_D	280_Y	1.053	0.70
150_I	245_A	1.051	0.69
205_I	496_I	1.040	0.69
517_E	545_A	1.036	0.68
255_L	263_L	1.027	0.68
363_E	376_L	1.027	0.68
252_K	283_E	1.026	0.67
510_A	545_A	1.023	0.67
397_E	401_Q	1.019	0.67
202_A	410_T	1.019	0.67
72_D	473_N	1.017	0.67
364_D	379_A	1.015	0.67
338_M	351_R	1.007	0.66
469_N	478_E	1.006	0.66
282_H	502_I	1.005	0.66
38_V	60_L	1.002	0.66
45_N	50_F	0.995	0.65
100_N	139_R	0.995	0.65
487_A	515_I	0.992	0.65
239_Q	272_N	0.990	0.65
175_S	214_V	0.988	0.65
270_N	325_S	0.987	0.64
332_D	374_P	0.985	0.64
397_E	400_R	0.983	0.64
130_I	177_S	0.980	0.64
157_F	257_F	0.979	0.64
130_I	190_N	0.978	0.64
253_A	257_F	0.974	0.63
446_A	463_T	0.970	0.63
67_T	234_K	0.969	0.63
181_I	184_W	0.959	0.62
559_Q	563_V	0.956	0.62
540_I	571_M	0.952	0.62
269_G	325_S	0.952	0.62
365_I	372_Q	0.949	0.61
491_L	508_F	0.948	0.61
46_K	577_K	0.948	0.61
540_I	544_I	0.948	0.61
123_T	467_F	0.935	0.60
515_I	542_V	0.934	0.60
455_T	538_V	0.934	0.60
339_V	345_E	0.932	0.60
83_Q	113_H	0.930	0.60
97_D	101_R	0.928	0.60
347_E	350_K	0.927	0.60
352_F	398_V	0.924	0.59
220_N	236_E	0.923	0.59
361_L	376_L	0.920	0.59
99_A	103_E	0.919	0.59
33_L	38_V	0.919	0.59
514_A	541_Q	0.917	0.59
109_L	117_M	0.916	0.59
154_E	158_E	0.915	0.58
420_E	424_E	0.915	0.58
126_V	194_G	0.915	0.58
147_I	153_I	0.915	0.58
222_E	225_L	0.907	0.58
176_E	239_Q	0.906	0.58
96_S	99_A	0.906	0.58
67_T	73_Q	0.905	0.58
225_L	234_K	0.905	0.58
194_G	201_A	0.904	0.58
64_L	68_V	0.903	0.57
169_L	199_Y	0.903	0.57
423_K	455_T	0.900	0.57
100_N	141_Q	0.899	0.57
203_A	269_G	0.894	0.57
93_V	138_R	0.894	0.57
335_R	339_V	0.892	0.57
499_E	557_N	0.889	0.56
298_T	361_L	0.889	0.56
123_T	297_I	0.887	0.56
328_I	354_T	0.885	0.56
128_E	442_H	0.884	0.56
358_R	361_L	0.882	0.56
536_Q	571_M	0.878	0.55
49_A	576_Y	0.876	0.55
363_E	379_A	0.876	0.55
86_P	90_R	0.876	0.55
171_V	264_H	0.874	0.55
166_D	209_R	0.872	0.55
419_E	455_T	0.871	0.55
532_I	542_V	0.870	0.55
85_Q	93_V	0.869	0.55
177_S	190_N	0.864	0.54
451_L	461_I	0.863	0.54
463_T	479_I	0.862	0.54
315_D	347_E	0.856	0.53
220_N	223_K	0.855	0.53
134_S	225_L	0.853	0.53
87_D	128_E	0.853	0.53
140_P	435_M	0.852	0.53
448_P	463_T	0.852	0.53
497_V	566_A	0.850	0.53
321_F	395_F	0.839	0.52
499_E	558_R	0.839	0.52
47_G	139_R	0.839	0.52
265_W	284_I	0.837	0.52
126_V	189_I	0.835	0.52
393_I	398_V	0.828	0.51
426_A	429_V	0.828	0.51
145_L	156_A	0.827	0.51
245_A	420_E	0.826	0.51
563_V	567_V	0.824	0.51
336_D	345_E	0.822	0.50
153_I	249_A	0.821	0.50
213_V	254_A	0.821	0.50
93_V	136_E	0.820	0.50
551_I	560_P	0.820	0.50
130_I	486_F	0.818	0.50
98_L	101_R	0.817	0.50
247_I	286_T	0.812	0.50
186_V	247_I	0.812	0.50
419_E	422_V	0.810	0.49
441_T	466_P	0.809	0.49
446_A	572_W	0.809	0.49
77_R	462_A	0.807	0.49
206_D	209_R	0.806	0.49
313_I	338_M	0.805	0.49
480_G	529_L	0.804	0.49
319_V	421_I	0.804	0.49
194_G	199_Y	0.797	0.48
404_P	425_M	0.795	0.48
196_L	480_G	0.790	0.48
149_N	152_G	0.790	0.48
139_R	431_R	0.789	0.48
475_V	526_A	0.789	0.48
33_L	41_I	0.789	0.48
274_R	375_Y	0.789	0.48
193_I	339_V	0.788	0.48
418_T	421_I	0.786	0.47
559_Q	562_D	0.785	0.47
48_V	574_P	0.785	0.47
357_Y	412_G	0.785	0.47
436_P	454_W	0.784	0.47
404_P	428_H	0.782	0.47
502_I	555_V	0.782	0.47
131_Q	442_H	0.781	0.47
63_L	159_N	0.781	0.47
314_K	343_L	0.780	0.47
346_E	350_K	0.780	0.47
506_A	549_A	0.778	0.47
522_E	525_G	0.778	0.47
214_V	361_L	0.777	0.47
177_S	486_F	0.772	0.46
69_L	101_R	0.772	0.46
547_A	551_I	0.770	0.46
176_E	410_T	0.769	0.46
320_I	408_I	0.768	0.46
274_R	371_F	0.766	0.46
177_S	192_A	0.766	0.46
327_G	528_L	0.764	0.45
398_V	402_A	0.762	0.45
353_Y	377_R	0.761	0.45
69_L	94_Y	0.756	0.45
566_A	570_A	0.755	0.45
433_V	462_A	0.754	0.45
93_V	542_V	0.753	0.44
186_V	231_I	0.752	0.44
262_L	285_L	0.752	0.44
298_T	482_S	0.751	0.44
219_T	225_L	0.750	0.44
444_A	467_F	0.747	0.44
437_M	467_F	0.747	0.44
194_G	481_Q	0.746	0.44
130_I	295_G	0.746	0.44
318_V	334_I	0.745	0.44
535_L	542_V	0.743	0.44
181_I	190_N	0.742	0.44
550_A	555_V	0.737	0.43
50_F	54_E	0.736	0.43
34_R	59_G	0.736	0.43
311_A	316_Q	0.734	0.43
135_H	229_L	0.733	0.43
317_R	404_P	0.733	0.43
419_E	453_K	0.732	0.43
501_R	557_N	0.732	0.43
287_F	466_P	0.731	0.43
307_K	517_E	0.729	0.42
357_Y	413_V	0.729	0.42
362_T	379_A	0.728	0.42
46_K	50_F	0.726	0.42
143_I	160_L	0.723	0.42
238_V	246_F	0.723	0.42
103_E	295_G	0.722	0.42
480_G	519_V	0.722	0.42
362_T	382_V	0.720	0.42
68_V	459_V	0.720	0.42
357_Y	365_I	0.720	0.42
80_E	83_Q	0.720	0.42
154_E	253_A	0.719	0.42
80_E	135_H	0.718	0.42
167_I	257_F	0.718	0.42
61_E	152_G	0.718	0.42
514_A	518_M	0.712	0.41
565_Q	568_L	0.712	0.41
493_L	571_M	0.710	0.41
352_F	405_T	0.709	0.41
411_S	416_A	0.709	0.41
497_V	570_A	0.706	0.40
92_N	333_Q	0.704	0.40
287_F	465_S	0.704	0.40
451_L	463_T	0.703	0.40
176_E	485_A	0.702	0.40
198_V	264_H	0.701	0.40
126_V	181_I	0.701	0.40
75_A	109_L	0.699	0.40
518_M	541_Q	0.699	0.40
523_T	534_K	0.697	0.40
514_A	542_V	0.697	0.40
123_T	291_I	0.696	0.40
60_L	64_L	0.696	0.40
265_W	486_F	0.695	0.40
339_V	343_L	0.694	0.39
202_A	532_I	0.693	0.39
51_S	54_E	0.693	0.39
269_G	272_N	0.692	0.39
308_K	431_R	0.691	0.39
485_A	567_V	0.691	0.39
270_N	372_Q	0.690	0.39
441_T	469_N	0.688	0.39
370_D	373_K	0.688	0.39
85_Q	94_Y	0.688	0.39
259_P	574_P	0.686	0.39
244_E	247_I	0.686	0.39
242_R	245_A	0.685	0.39
336_D	339_V	0.684	0.39
556_A	559_Q	0.682	0.38
338_M	342_G	0.682	0.38
358_R	365_I	0.682	0.38
146_S	246_F	0.681	0.38
274_R	291_I	0.681	0.38
130_I	192_A	0.681	0.38
147_I	150_I	0.680	0.38
551_I	556_A	0.680	0.38
396_D	399_V	0.679	0.38
134_S	187_G	0.679	0.38
264_H	482_S	0.678	0.38
467_F	488_F	0.677	0.38
243_Y	269_G	0.675	0.38
306_M	312_S	0.675	0.38
181_I	410_T	0.674	0.38
518_M	534_K	0.673	0.38
245_A	249_A	0.673	0.38
115_R	531_S	0.672	0.38
312_S	341_A	0.670	0.38
123_T	412_G	0.669	0.37
225_L	469_N	0.668	0.37
535_L	539_S	0.668	0.37
242_R	350_K	0.667	0.37
306_M	311_A	0.667	0.37
176_E	243_Y	0.666	0.37
198_V	286_T	0.664	0.37
104_V	327_G	0.664	0.37
327_G	410_T	0.664	0.37
274_R	325_S	0.663	0.37
500_A	503_I	0.663	0.37
423_K	454_W	0.663	0.37
107_Y	434_I	0.663	0.37
68_V	87_D	0.662	0.37
302_V	306_M	0.661	0.37
269_G	485_A	0.661	0.37
256_K	423_K	0.660	0.37
524_P	527_G	0.660	0.37
265_W	276_I	0.659	0.37
130_I	410_T	0.659	0.37
85_Q	485_A	0.658	0.37
221_N	226_N	0.658	0.37
513_D	517_E	0.658	0.37
319_V	377_R	0.657	0.36
410_T	486_F	0.654	0.36
169_L	262_L	0.654	0.36
48_V	69_L	0.654	0.36
538_V	542_V	0.654	0.36
520_D	523_T	0.652	0.36
158_E	234_K	0.647	0.36
451_L	572_W	0.646	0.36
428_H	455_T	0.646	0.36
130_I	175_S	0.646	0.36
108_K	575_E	0.643	0.35
181_I	486_F	0.643	0.35
285_L	295_G	0.642	0.35
455_T	459_V	0.642	0.35
94_Y	137_Y	0.642	0.35
540_I	567_V	0.641	0.35
129_A	142_G	0.640	0.35
141_Q	285_L	0.638	0.35
213_V	247_I	0.638	0.35
72_D	112_N	0.637	0.35
225_L	235_H	0.636	0.35
262_L	491_L	0.636	0.35
240_G	243_Y	0.636	0.35
54_E	74_Q	0.635	0.35
342_G	348_A	0.635	0.35
91_Q	116_E	0.634	0.35
500_A	546_V	0.634	0.35
533_D	552_K	0.633	0.35
350_K	399_V	0.633	0.35
295_G	410_T	0.631	0.34
394_P	398_V	0.631	0.34
461_I	470_V	0.629	0.34
202_A	330_I	0.629	0.34
548_E	551_I	0.628	0.34
321_F	355_L	0.628	0.34
323_A	354_T	0.626	0.34
89_L	93_V	0.624	0.34
504_T	550_A	0.624	0.34
132_E	135_H	0.623	0.34
107_Y	278_K	0.623	0.34
336_D	349_N	0.622	0.34
103_E	138_R	0.621	0.34
469_N	476_S	0.620	0.34
169_L	198_V	0.620	0.34
446_A	450_D	0.619	0.33
130_I	184_W	0.619	0.33
189_I	192_A	0.619	0.33
426_A	430_D	0.618	0.33
106_F	110_L	0.618	0.33
106_F	504_T	0.617	0.33
500_A	555_V	0.617	0.33
74_Q	105_L	0.617	0.33
129_A	462_A	0.616	0.33
88_R	128_E	0.616	0.33
161_H	249_A	0.616	0.33
190_N	487_A	0.616	0.33
521_L	524_P	0.614	0.33
419_E	450_D	0.613	0.33
91_Q	120_V	0.612	0.33
240_G	272_N	0.611	0.33
447_V	461_I	0.611	0.33
370_D	411_S	0.610	0.33
145_L	155_K	0.610	0.33
197_A	542_V	0.610	0.33
49_A	70_S	0.610	0.33
152_G	155_K	0.608	0.33
302_V	435_M	0.608	0.33
191_I	439_N	0.607	0.33
39_L	64_L	0.607	0.33
412_G	443_L	0.607	0.33
407_L	490_G	0.606	0.32
177_S	198_V	0.606	0.32
244_E	248_D	0.606	0.32
127_G	173_T	0.604	0.32
332_D	349_N	0.604	0.32
95_L	342_G	0.604	0.32
372_Q	529_L	0.604	0.32
418_T	450_D	0.603	0.32
403_K	451_L	0.602	0.32
177_S	410_T	0.602	0.32
34_R	38_V	0.600	0.32
536_Q	573_T	0.600	0.32
354_T	361_L	0.600	0.32
217_V	243_Y	0.600	0.32
92_N	295_G	0.599	0.32
261_A	276_I	0.599	0.32
126_V	264_H	0.598	0.32
264_H	486_F	0.598	0.32
326_A	439_N	0.597	0.32
399_V	449_E	0.597	0.32
344_S	350_K	0.597	0.32
414_S	450_D	0.596	0.32
264_H	287_F	0.596	0.32
161_H	164_A	0.596	0.32
123_T	442_H	0.596	0.32
48_V	98_L	0.594	0.32
71_L	75_A	0.594	0.32
426_A	456_D	0.593	0.31
465_S	539_S	0.593	0.31
350_K	377_R	0.593	0.31
169_L	181_I	0.592	0.31
469_N	502_I	0.592	0.31
55_R	64_L	0.592	0.31
82_F	109_L	0.591	0.31
181_I	192_A	0.591	0.31
424_E	429_V	0.590	0.31
490_G	550_A	0.590	0.31
475_V	525_G	0.589	0.31
144_Y	168_D	0.589	0.31
298_T	437_M	0.589	0.31
507_M	553_D	0.589	0.31
405_T	429_V	0.588	0.31
403_K	501_R	0.588	0.31
414_S	418_T	0.588	0.31
446_A	479_I	0.585	0.31
133_Y	330_I	0.585	0.31
486_F	542_V	0.585	0.31
147_I	567_V	0.584	0.31
422_V	450_D	0.584	0.31
133_Y	197_A	0.584	0.31
333_Q	508_F	0.584	0.31
198_V	265_W	0.584	0.31
335_R	376_L	0.583	0.31
436_P	452_F	0.583	0.31
210_V	264_H	0.582	0.31
308_K	521_L	0.582	0.31
520_D	525_G	0.582	0.31
130_I	264_H	0.582	0.31
49_A	74_Q	0.581	0.31
444_A	447_V	0.581	0.31
308_K	460_L	0.580	0.30
545_A	548_E	0.580	0.30
74_Q	102_N	0.580	0.30
37_E	41_I	0.579	0.30
436_P	542_V	0.578	0.30
146_S	149_N	0.577	0.30
130_I	169_L	0.576	0.30
439_N	466_P	0.575	0.30
291_I	325_S	0.575	0.30
355_L	421_I	0.575	0.30
412_G	437_M	0.575	0.30
41_I	56_Q	0.574	0.30
339_V	565_Q	0.574	0.30
274_R	332_D	0.572	0.30
52_L	56_Q	0.572	0.30
303_L	513_D	0.571	0.30
106_F	197_A	0.571	0.30
73_Q	234_K	0.571	0.30
556_A	560_P	0.570	0.30
350_K	453_K	0.570	0.30
85_Q	97_D	0.570	0.30
155_K	475_V	0.569	0.30
176_E	529_L	0.568	0.30
347_E	449_E	0.568	0.30
444_A	451_L	0.567	0.30
448_P	467_F	0.567	0.30
318_V	406_I	0.566	0.29
150_I	253_A	0.566	0.29
272_N	333_Q	0.566	0.29
265_W	396_D	0.565	0.29
172_A	221_N	0.565	0.29
122_Y	191_I	0.564	0.29
100_N	138_R	0.564	0.29
294_T	484_N	0.564	0.29
394_P	421_I	0.564	0.29
196_L	210_V	0.564	0.29
201_A	482_S	0.564	0.29
194_G	482_S	0.564	0.29
104_V	576_Y	0.563	0.29
544_I	548_E	0.562	0.29
458_K	552_K	0.562	0.29
437_M	444_A	0.561	0.29
117_M	120_V	0.560	0.29
151_D	215_L	0.560	0.29
311_A	405_T	0.559	0.29
532_I	535_L	0.557	0.29
330_I	485_A	0.556	0.29
358_R	413_V	0.556	0.29
465_S	488_F	0.556	0.29
237_R	243_Y	0.556	0.29
176_E	330_I	0.555	0.29
42_P	45_N	0.555	0.29
406_I	433_V	0.554	0.29
107_Y	193_I	0.554	0.29
507_M	542_V	0.554	0.29
186_V	508_F	0.553	0.29
77_R	317_R	0.552	0.28
379_A	382_V	0.550	0.28
77_R	229_L	0.550	0.28
76_Q	80_E	0.549	0.28
503_I	546_V	0.549	0.28
200_T	469_N	0.548	0.28
510_A	549_A	0.548	0.28
41_I	44_L	0.548	0.28
514_A	517_E	0.548	0.28
310_G	423_K	0.547	0.28
215_L	311_A	0.547	0.28
73_Q	90_R	0.547	0.28
177_S	270_N	0.544	0.28
114_L	575_E	0.544	0.28
102_N	105_L	0.544	0.28
132_E	435_M	0.543	0.28
439_N	484_N	0.543	0.28
278_K	282_H	0.542	0.28
239_Q	242_R	0.542	0.28
265_W	323_A	0.542	0.28
546_V	550_A	0.542	0.28
515_I	545_A	0.542	0.28
486_F	532_I	0.540	0.28
321_F	412_G	0.539	0.28
134_S	491_L	0.539	0.28
344_S	449_E	0.539	0.28
336_D	505_P	0.538	0.27
62_G	159_N	0.537	0.27
152_G	453_K	0.537	0.27
532_I	539_S	0.537	0.27
117_M	515_I	0.536	0.27
481_Q	484_N	0.536	0.27
48_V	59_G	0.536	0.27
134_S	508_F	0.535	0.27
133_Y	189_I	0.535	0.27
69_L	133_Y	0.535	0.27
221_N	357_Y	0.535	0.27
132_E	283_E	0.534	0.27
268_L	466_P	0.534	0.27
497_V	567_V	0.534	0.27
270_N	369_L	0.534	0.27
495_S	498_A	0.534	0.27
142_G	467_F	0.533	0.27
299_L	337_T	0.533	0.27
452_F	459_V	0.533	0.27
203_A	482_S	0.532	0.27
551_I	563_V	0.531	0.27
72_D	537_E	0.531	0.27
72_D	260_K	0.531	0.27
192_A	214_V	0.531	0.27
301_G	308_K	0.530	0.27
265_W	320_I	0.530	0.27
361_L	506_A	0.529	0.27
306_M	309_T	0.529	0.27
144_Y	542_V	0.529	0.27
444_A	465_S	0.529	0.27
552_K	555_V	0.528	0.27
131_Q	488_F	0.528	0.27
112_N	116_E	0.527	0.27
34_R	58_L	0.527	0.27
149_N	257_F	0.527	0.27
143_I	151_D	0.526	0.27
551_I	558_R	0.526	0.27
107_Y	501_R	0.526	0.27
198_V	486_F	0.525	0.27
76_Q	87_D	0.524	0.27
337_T	341_A	0.522	0.26
339_V	348_A	0.521	0.26
446_A	454_W	0.521	0.26
56_Q	155_K	0.520	0.26
243_Y	272_N	0.520	0.26
367_G	490_G	0.519	0.26
395_F	398_V	0.518	0.26
123_T	439_N	0.517	0.26
507_M	549_A	0.517	0.26
482_S	524_P	0.517	0.26
104_V	258_F	0.517	0.26
304_A	528_L	0.516	0.26
69_L	81_Q	0.516	0.26
148_D	242_R	0.515	0.26
133_Y	299_L	0.515	0.26
76_Q	228_P	0.513	0.26
370_D	421_I	0.513	0.26
203_A	333_Q	0.513	0.26
339_V	342_G	0.513	0.26
276_I	486_F	0.513	0.26
514_A	543_A	0.513	0.26
107_Y	241_E	0.512	0.26
281_N	435_M	0.512	0.26
373_K	561_E	0.512	0.26
279_K	319_V	0.511	0.26
518_M	538_V	0.511	0.26
452_F	470_V	0.510	0.26
356_D	365_I	0.509	0.26
123_T	287_F	0.509	0.26
310_G	350_K	0.509	0.26
220_N	333_Q	0.508	0.25
93_V	235_H	0.508	0.25
500_A	547_A	0.508	0.25
34_R	37_E	0.508	0.25
100_N	398_V	0.508	0.25
52_L	61_E	0.508	0.25
309_T	312_S	0.507	0.25
123_T	466_P	0.506	0.25
269_G	275_N	0.505	0.25
192_A	196_L	0.505	0.25
248_D	255_L	0.505	0.25
508_F	511_T	0.504	0.25
147_I	215_L	0.504	0.25
265_W	354_T	0.504	0.25
272_N	485_A	0.504	0.25
442_H	465_S	0.503	0.25
281_N	418_T	0.503	0.25
422_V	459_V	0.502	0.25
436_P	446_A	0.502	0.25
160_L	572_W	0.502	0.25
83_Q	117_M	0.502	0.25
347_E	453_K	0.501	0.25
143_I	213_V	0.500	0.25
239_Q	265_W	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1o0sA	4	0.9691	100	0.163	Contact Map
1gq2A	6	0.9244	100	0.163	Contact Map
1pj3A	4	0.9313	100	0.167	Contact Map
3nv9A	2	0.7663	100	0.546	Contact Map
1vl6A	4	0.6289	100	0.615	Contact Map
2a9fA	2	0.6478	100	0.669	Contact Map
2dvmA	2	0.7027	100	0.675	Contact Map
4ppmA	2	0.0344	99.4	0.944	Contact Map
1v8bA	4	0.7268	98.9	0.956	Contact Map
3aoeE	3	0.6495	98.5	0.962	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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