ACDA - BACSU - GREMLIN Contacts

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ACDA - Acyl-CoA dehydrogenase

UniProt:	P45867	Sequences: MNFSLSEEHEMIRKLVRDFAKHEVAPTAAERDEQERFDRELFREMANLGLTGIPWPEDYGGIGSDYLAYVIAVEELSKVCASTGVTLSAHISLCSWPLFAFGTEEQKTEYLTQLALGEKIGAFALTEAGSGSDAGSMKTTAERIGDDYVLNGSKVFITNGGVADIYIVFAVTDPEKKKKGVTAFIVEKDFEGFFTGKKEKKLGIRSSPTTEIMFEDCVVPASKRLGEEGEGFKIAMKTLDGGRNGIAAQAVGIAQGALDAALQYAKERKQFGKSIAEQQGIAFKLADMATMIEASRLLTYQAAWLESSGLPYGKASAMSKLMAGDTAMKVTTEAVQIFGGYGYTKDYPVERYMRDAKITQIYEGTQEIQRLVISRMLAD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	379 (365)
Sequences:	33869 (19267)
Seq/√Len:	1008.5

ECOLI - CAIA YDIO AIDB FADE
BACSU - ACDA ACDC ACDB FADE YDBM
HALSA - Q9HS75 Q9HRB3 Q9HRI6 Q9HPT2 Q9HQF0 Q9HMK7
SULSO - Q97UW6 Q97V73 Q97U78 Q97WQ8 Q97VU6 Q97XW3 Q97YZ6 Q97VV8 Q97YZ3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
147_D	218_V	3.968	1.00
151_N	216_D	3.901	1.00
291_M	329_K	3.369	1.00
23_E	44_E	3.246	1.00
144_I	218_V	2.918	1.00
194_F	215_E	2.897	1.00
113_Q	118_E	2.845	1.00
143_R	221_A	2.798	1.00
104_E	108_T	2.794	1.00
182_T	224_R	2.739	1.00
17_R	75_E	2.708	1.00
65_D	68_A	2.700	1.00
30_E	34_Q	2.623	1.00
284_K	333_E	2.346	1.00
263_Q	267_E	2.326	1.00
113_Q	119_K	2.224	1.00
153_S	213_M	2.193	1.00
255_Q	296_R	2.180	1.00
170_A	184_F	2.114	1.00
304_W	308_S	2.084	1.00
104_E	107_K	2.069	1.00
227_E	230_E	2.028	1.00
144_I	147_D	2.025	1.00
18_D	22_H	2.021	1.00
274_S	277_E	2.014	1.00
103_T	106_Q	2.004	1.00
265_A	337_I	1.978	1.00
345_K	350_E	1.940	1.00
74_E	296_R	1.911	1.00
350_E	354_R	1.857	1.00
56_P	99_F	1.856	1.00
230_E	233_K	1.855	1.00
166_Y	188_K	1.820	1.00
148_Y	184_F	1.799	1.00
325_D	366_Q	1.765	1.00
44_E	47_N	1.754	1.00
258_L	292_I	1.751	1.00
78_K	259_D	1.731	1.00
153_S	211_E	1.719	1.00
9_H	68_A	1.715	1.00
255_Q	259_D	1.713	1.00
43_R	47_N	1.695	1.00
143_R	228_E	1.687	1.00
160_G	210_T	1.666	1.00
144_I	149_V	1.657	1.00
142_E	151_N	1.642	1.00
269_K	274_S	1.640	1.00
220_P	223_K	1.629	1.00
122_A	166_Y	1.626	1.00
75_E	78_K	1.625	1.00
265_A	281_I	1.608	1.00
280_G	283_F	1.599	1.00
305_L	315_A	1.589	1.00
149_V	218_V	1.587	1.00
146_D	218_V	1.579	1.00
190_F	217_C	1.572	1.00
109_E	222_S	1.566	1.00
288_M	330_V	1.553	1.00
149_V	216_D	1.541	1.00
148_Y	221_A	1.541	1.00
126_T	156_F	1.535	1.00
109_E	113_Q	1.528	1.00
224_R	228_E	1.526	1.00
127_E	154_K	1.522	1.00
151_N	215_E	1.517	1.00
260_A	348_P	1.517	1.00
187_E	223_K	1.511	1.00
273_K	277_E	1.509	1.00
294_A	322_M	1.505	1.00
194_F	213_M	1.494	1.00
10_E	13_R	1.494	1.00
146_D	221_A	1.476	1.00
57_E	63_G	1.475	1.00
301_Q	305_L	1.474	1.00
113_Q	116_L	1.470	1.00
11_M	14_K	1.468	1.00
9_H	65_D	1.468	1.00
281_I	337_I	1.464	1.00
59_Y	107_K	1.463	1.00
257_A	331_T	1.461	1.00
14_K	18_D	1.452	1.00
20_A	79_V	1.451	1.00
143_R	147_D	1.451	1.00
141_A	184_F	1.439	1.00
270_Q	278_Q	1.430	1.00
161_G	210_T	1.421	1.00
221_A	224_R	1.412	1.00
150_L	184_F	1.412	1.00
295_S	323_A	1.411	1.00
196_G	211_E	1.411	1.00
108_T	112_T	1.405	1.00
341_Y	347_Y	1.405	1.00
9_H	71_I	1.395	1.00
293_E	301_Q	1.385	1.00
260_A	263_Q	1.384	1.00
106_Q	110_Y	1.381	1.00
196_G	213_M	1.360	1.00
11_M	15_L	1.355	1.00
80_C	83_T	1.354	1.00
105_E	109_E	1.354	1.00
321_L	366_Q	1.350	1.00
187_E	190_F	1.349	1.00
262_L	266_K	1.347	1.00
256_G	260_A	1.345	1.00
328_M	360_Q	1.337	1.00
74_E	300_Y	1.331	1.00
13_R	75_E	1.331	1.00
78_K	255_Q	1.327	1.00
67_L	304_W	1.318	1.00
288_M	333_E	1.318	1.00
332_T	357_K	1.314	1.00
16_V	50_L	1.312	1.00
329_K	333_E	1.307	1.00
219_V	223_K	1.298	1.00
147_D	221_A	1.297	1.00
53_I	72_A	1.296	1.00
101_F	237_K	1.295	1.00
105_E	222_S	1.285	1.00
66_Y	307_S	1.280	1.00
200_K	345_K	1.269	1.00
173_D	176_K	1.261	1.00
114_L	121_G	1.255	1.00
33_E	200_K	1.253	1.00
74_E	255_Q	1.248	1.00
107_K	111_L	1.247	1.00
39_R	43_R	1.245	1.00
254_A	292_I	1.243	1.00
287_D	370_R	1.241	1.00
193_F	217_C	1.235	1.00
292_I	330_V	1.233	1.00
31_R	206_S	1.221	1.00
254_A	330_V	1.215	1.00
261_A	334_A	1.212	1.00
188_K	193_F	1.210	1.00
124_A	157_I	1.208	1.00
143_R	148_Y	1.207	1.00
43_R	46_A	1.202	1.00
258_L	262_L	1.198	1.00
77_S	84_G	1.195	1.00
65_D	307_S	1.194	1.00
248_A	299_T	1.186	1.00
10_E	14_K	1.184	1.00
112_T	116_L	1.181	1.00
172_T	182_T	1.174	1.00
332_T	360_Q	1.174	1.00
70_V	303_A	1.170	1.00
242_G	363_E	1.168	1.00
327_A	356_A	1.166	1.00
190_F	223_K	1.164	1.00
256_G	352_Y	1.160	1.00
273_K	278_Q	1.158	1.00
64_S	68_A	1.151	1.00
129_G	138_K	1.149	1.00
301_Q	304_W	1.149	1.00
232_F	236_M	1.145	1.00
55_W	115_A	1.145	1.00
142_E	149_V	1.144	1.00
240_D	313_G	1.144	1.00
13_R	71_I	1.142	1.00
44_E	48_L	1.141	1.00
334_A	349_V	1.138	1.00
70_V	248_A	1.134	1.00
109_E	223_K	1.134	1.00
102_G	106_Q	1.132	1.00
289_A	293_E	1.131	1.00
148_Y	228_E	1.129	1.00
15_L	48_L	1.123	1.00
284_K	367_E	1.117	1.00
305_L	310_L	1.111	1.00
169_F	183_A	1.106	1.00
260_A	338_F	1.103	1.00
119_K	164_D	1.103	1.00
110_Y	165_I	1.100	1.00
27_T	31_R	1.100	1.00
139_T	150_L	1.093	1.00
140_T	151_N	1.093	1.00
106_Q	185_I	1.089	1.00
295_S	326_T	1.089	1.00
357_K	360_Q	1.086	1.00
168_V	186_V	1.083	1.00
192_G	217_C	1.078	1.00
150_L	168_V	1.076	1.00
317_A	369_Q	1.075	1.00
251_V	292_I	1.075	1.00
188_K	195_T	1.072	1.00
193_F	212_I	1.071	1.00
105_E	108_T	1.070	1.00
328_M	332_T	1.061	1.00
290_T	318_M	1.060	1.00
148_Y	172_T	1.059	1.00
16_V	20_A	1.058	1.00
291_M	333_E	1.056	1.00
46_A	51_T	1.054	1.00
43_R	118_E	1.051	1.00
15_L	50_L	1.041	1.00
58_D	108_T	1.040	1.00
142_E	216_D	1.033	1.00
124_A	166_Y	1.031	1.00
169_F	181_V	1.028	1.00
360_Q	366_Q	1.028	1.00
29_A	33_E	1.019	1.00
121_G	165_I	1.018	1.00
150_L	170_A	1.012	1.00
141_A	170_A	1.011	1.00
133_D	136_S	1.008	1.00
168_V	214_F	0.993	1.00
218_V	221_A	0.991	1.00
27_T	30_E	0.990	1.00
251_V	299_T	0.989	1.00
331_T	356_A	0.984	1.00
94_C	121_G	0.980	1.00
182_T	228_E	0.979	1.00
39_R	164_D	0.977	1.00
40_E	43_R	0.973	1.00
19_F	44_E	0.972	1.00
325_D	329_K	0.970	1.00
291_M	326_T	0.970	1.00
265_A	275_I	0.955	1.00
173_D	180_G	0.955	1.00
328_M	353_M	0.954	1.00
142_E	173_D	0.953	1.00
166_Y	193_F	0.951	1.00
266_K	276_A	0.949	1.00
250_A	359_T	0.947	1.00
100_A	237_K	0.947	1.00
325_D	360_Q	0.945	1.00
166_Y	212_I	0.941	1.00
109_E	187_E	0.941	1.00
160_G	195_T	0.938	1.00
321_L	370_R	0.938	1.00
124_A	214_F	0.937	1.00
257_A	352_Y	0.936	1.00
94_C	167_I	0.936	1.00
184_F	224_R	0.933	1.00
262_L	285_L	0.929	1.00
366_Q	370_R	0.928	1.00
156_F	341_Y	0.928	1.00
150_L	219_V	0.923	1.00
16_V	72_A	0.921	1.00
204_I	358_I	0.919	1.00
145_G	218_V	0.917	1.00
297_L	301_Q	0.916	1.00
106_Q	223_K	0.909	1.00
326_T	329_K	0.900	1.00
202_L	353_M	0.899	1.00
302_A	319_S	0.898	1.00
324_G	366_Q	0.893	1.00
55_W	95_S	0.893	1.00
32_D	354_R	0.893	1.00
103_T	107_K	0.886	1.00
56_P	59_Y	0.883	1.00
358_I	362_Y	0.882	1.00
265_A	276_A	0.882	1.00
287_D	291_M	0.882	1.00
17_R	21_K	0.879	1.00
165_I	187_E	0.877	1.00
289_A	318_M	0.874	1.00
58_D	104_E	0.873	1.00
155_V	211_E	0.873	1.00
191_E	218_V	0.872	1.00
33_E	345_K	0.871	1.00
122_A	163_A	0.871	1.00
122_A	188_K	0.868	1.00
19_F	48_L	0.866	1.00
259_D	263_Q	0.860	1.00
20_A	76_L	0.860	1.00
67_L	307_S	0.859	1.00
263_Q	266_K	0.857	1.00
45_M	50_L	0.857	1.00
325_D	370_R	0.857	1.00
101_F	234_I	0.843	1.00
335_V	353_M	0.842	1.00
156_F	344_T	0.842	1.00
132_S	368_I	0.841	1.00
125_L	239_L	0.838	1.00
261_A	337_I	0.837	1.00
164_D	189_D	0.834	1.00
59_Y	104_E	0.831	1.00
171_V	181_V	0.829	1.00
265_A	285_L	0.828	1.00
19_F	45_M	0.828	1.00
326_T	330_V	0.827	1.00
82_S	206_S	0.826	1.00
328_M	357_K	0.826	1.00
21_K	78_K	0.823	1.00
203_G	355_D	0.822	1.00
335_V	349_V	0.822	1.00
283_F	371_L	0.822	1.00
291_M	322_M	0.817	1.00
202_L	350_E	0.816	1.00
359_T	362_Y	0.816	1.00
27_T	40_E	0.815	1.00
214_F	217_C	0.813	1.00
19_F	23_E	0.812	1.00
165_I	185_I	0.811	1.00
253_I	356_A	0.811	1.00
282_A	371_L	0.808	1.00
141_A	148_Y	0.808	1.00
9_H	67_L	0.808	1.00
261_A	338_F	0.807	1.00
67_L	71_I	0.806	1.00
253_I	327_A	0.803	1.00
13_R	17_R	0.802	1.00
67_L	300_Y	0.800	1.00
184_F	219_V	0.797	1.00
182_T	229_G	0.796	1.00
253_I	352_Y	0.796	1.00
124_A	168_V	0.795	1.00
119_K	165_I	0.792	1.00
195_T	212_I	0.791	1.00
261_A	265_A	0.791	1.00
148_Y	224_R	0.790	1.00
29_A	351_R	0.789	1.00
283_F	287_D	0.788	1.00
58_D	61_G	0.786	1.00
141_A	172_T	0.786	1.00
190_F	193_F	0.785	1.00
254_A	326_T	0.784	1.00
147_D	220_P	0.784	1.00
150_L	186_V	0.783	1.00
331_T	352_Y	0.780	1.00
71_I	75_E	0.779	1.00
293_E	296_R	0.777	1.00
167_I	183_A	0.776	1.00
147_D	222_S	0.776	1.00
293_E	297_L	0.775	1.00
15_L	18_D	0.774	1.00
332_T	353_M	0.773	1.00
284_K	337_I	0.772	1.00
246_I	363_E	0.768	1.00
290_T	322_M	0.767	1.00
137_M	169_F	0.766	1.00
331_T	353_M	0.766	1.00
247_A	319_S	0.765	1.00
275_I	278_Q	0.762	1.00
54_P	69_Y	0.761	1.00
110_Y	185_I	0.753	1.00
288_M	334_A	0.752	1.00
251_V	295_S	0.750	1.00
258_L	289_A	0.749	1.00
137_M	181_V	0.748	1.00
41_L	83_T	0.747	1.00
58_D	107_K	0.746	1.00
260_A	352_Y	0.740	1.00
268_R	271_F	0.738	1.00
124_A	212_I	0.737	1.00
95_S	114_L	0.735	1.00
164_D	188_K	0.733	1.00
336_Q	357_K	0.730	1.00
351_R	355_D	0.729	1.00
353_M	357_K	0.726	1.00
204_I	362_Y	0.724	1.00
279_Q	283_F	0.721	1.00
287_D	333_E	0.721	1.00
139_T	154_K	0.720	1.00
264_Y	341_Y	0.719	1.00
173_D	229_G	0.717	1.00
298_L	318_M	0.715	1.00
171_V	174_P	0.712	1.00
294_A	298_L	0.711	1.00
30_E	33_E	0.711	1.00
21_K	79_V	0.710	1.00
71_I	300_Y	0.710	1.00
78_K	256_G	0.710	1.00
182_T	226_G	0.709	1.00
255_Q	289_A	0.709	1.00
224_R	227_E	0.707	1.00
40_E	44_E	0.707	1.00
322_M	326_T	0.706	1.00
287_D	329_K	0.705	1.00
24_V	41_L	0.705	1.00
189_D	193_F	0.704	1.00
257_A	334_A	0.704	1.00
172_T	180_G	0.703	1.00
127_E	139_T	0.699	1.00
298_L	319_S	0.699	1.00
39_R	162_V	0.698	1.00
250_A	324_G	0.698	1.00
312_Y	315_A	0.697	1.00
331_T	349_V	0.696	1.00
110_Y	223_K	0.693	1.00
167_I	225_L	0.691	1.00
290_T	321_L	0.689	1.00
278_Q	282_A	0.687	1.00
20_A	24_V	0.686	1.00
247_A	299_T	0.686	1.00
123_F	235_A	0.684	1.00
13_R	74_E	0.684	1.00
329_K	332_T	0.683	1.00
56_P	61_G	0.683	1.00
53_I	64_S	0.682	1.00
371_L	375_R	0.679	1.00
137_M	171_V	0.677	1.00
369_Q	372_V	0.674	1.00
114_L	165_I	0.673	1.00
145_G	149_V	0.672	1.00
303_A	307_S	0.671	1.00
200_K	205_R	0.670	1.00
125_L	134_A	0.670	1.00
282_A	374_S	0.670	1.00
327_A	331_T	0.668	1.00
247_A	323_A	0.666	1.00
58_D	63_G	0.665	1.00
171_V	180_G	0.665	1.00
110_Y	119_K	0.663	1.00
335_V	342_G	0.662	1.00
161_G	208_P	0.660	1.00
12_I	72_A	0.660	1.00
230_E	234_I	0.659	1.00
365_T	368_I	0.657	1.00
106_Q	109_E	0.657	1.00
144_I	221_A	0.652	1.00
21_K	25_A	0.646	1.00
143_R	149_V	0.644	1.00
102_G	107_K	0.643	1.00
338_F	349_V	0.643	1.00
291_M	294_A	0.642	1.00
299_T	323_A	0.641	1.00
41_L	44_E	0.640	1.00
176_K	179_K	0.638	1.00
296_R	300_Y	0.638	1.00
281_I	285_L	0.638	1.00
18_D	21_K	0.637	1.00
298_L	322_M	0.636	1.00
157_I	212_I	0.635	1.00
28_A	351_R	0.632	1.00
153_S	196_G	0.629	1.00
55_W	59_Y	0.626	1.00
32_D	205_R	0.624	1.00
244_N	303_A	0.623	1.00
270_Q	275_I	0.621	1.00
248_A	252_G	0.618	1.00
85_V	204_I	0.615	1.00
160_G	212_I	0.611	1.00
171_V	176_K	0.611	1.00
254_A	295_S	0.608	1.00
340_G	343_Y	0.607	1.00
205_R	345_K	0.607	1.00
261_A	288_M	0.606	1.00
97_P	238_T	0.605	1.00
172_T	228_E	0.603	1.00
240_D	316_S	0.603	1.00
321_L	373_I	0.603	1.00
203_G	343_Y	0.599	1.00
17_R	79_V	0.597	1.00
12_I	68_A	0.597	1.00
256_G	259_D	0.592	1.00
139_T	214_F	0.592	1.00
29_A	348_P	0.591	1.00
254_A	257_A	0.589	1.00
143_R	146_D	0.588	1.00
318_M	373_I	0.588	1.00
271_F	278_Q	0.586	1.00
95_S	111_L	0.586	1.00
35_E	200_K	0.585	1.00
140_T	174_P	0.583	1.00
139_T	152_G	0.582	1.00
169_F	235_A	0.581	1.00
295_S	319_S	0.581	1.00
256_G	348_P	0.581	1.00
186_V	214_F	0.581	1.00
17_R	78_K	0.579	1.00
39_R	120_I	0.579	1.00
177_K	180_G	0.578	1.00
306_E	312_Y	0.575	1.00
221_A	228_E	0.575	1.00
128_A	153_S	0.574	1.00
201_K	209_T	0.573	1.00
281_I	284_K	0.572	1.00
284_K	287_D	0.571	1.00
295_S	322_M	0.569	1.00
348_P	351_R	0.569	1.00
293_E	298_L	0.568	1.00
291_M	325_D	0.568	1.00
69_Y	245_G	0.565	1.00
290_T	294_A	0.564	1.00
59_Y	112_T	0.564	1.00
94_C	97_P	0.559	1.00
284_K	336_Q	0.559	1.00
12_I	16_V	0.559	1.00
25_A	28_A	0.559	1.00
98_L	102_G	0.558	1.00
202_L	354_R	0.558	1.00
264_Y	347_Y	0.557	1.00
251_V	255_Q	0.554	1.00
184_F	223_K	0.554	1.00
301_Q	315_A	0.552	1.00
109_E	112_T	0.551	1.00
189_D	192_G	0.551	1.00
324_G	359_T	0.550	1.00
168_V	217_C	0.549	1.00
368_I	371_L	0.548	1.00
140_T	173_D	0.546	1.00
52_G	62_I	0.545	1.00
94_C	114_L	0.544	1.00
184_F	221_A	0.543	1.00
81_A	253_I	0.542	1.00
288_M	337_I	0.541	1.00
193_F	214_F	0.540	1.00
269_K	277_E	0.538	1.00
158_T	209_T	0.538	1.00
165_I	223_K	0.537	1.00
143_R	184_F	0.537	1.00
99_F	107_K	0.537	1.00
205_R	355_D	0.537	1.00
287_D	290_T	0.536	1.00
66_Y	306_E	0.535	1.00
321_L	325_D	0.534	1.00
357_K	361_I	0.534	1.00
244_N	299_T	0.533	1.00
15_L	62_I	0.532	1.00
31_R	80_C	0.531	1.00
45_M	83_T	0.531	1.00
328_M	356_A	0.530	1.00
59_Y	108_T	0.530	1.00
143_R	218_V	0.528	1.00
268_R	340_G	0.528	1.00
295_S	330_V	0.528	1.00
139_T	168_V	0.528	1.00
125_L	169_F	0.528	1.00
255_Q	292_I	0.527	1.00
287_D	325_D	0.526	1.00
298_L	302_A	0.526	1.00
348_P	352_Y	0.526	1.00
97_P	101_F	0.526	1.00
147_D	223_K	0.525	1.00
24_V	83_T	0.524	1.00
35_E	205_R	0.524	1.00
172_T	184_F	0.524	1.00
288_M	326_T	0.523	1.00
71_I	74_E	0.523	1.00
97_P	234_I	0.521	1.00
148_Y	219_V	0.520	1.00
70_V	300_Y	0.520	1.00
275_I	281_I	0.518	1.00
264_Y	267_E	0.517	1.00
162_V	208_P	0.517	1.00
239_L	242_G	0.514	1.00
278_Q	281_I	0.514	1.00
291_M	295_S	0.512	1.00
189_D	195_T	0.511	1.00
186_V	217_C	0.510	1.00
50_L	72_A	0.509	1.00
336_Q	367_E	0.509	1.00
369_Q	373_I	0.508	1.00
141_A	150_L	0.508	1.00
57_E	60_G	0.507	1.00
110_Y	187_E	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2d29A	4	1	100	0.069	Contact Map
4l1fA	4	1	100	0.069	Contact Map
1bucA	4	1	100	0.071	Contact Map
1ukwA	4	0.9974	100	0.075	Contact Map
4m9aA	4	0.9921	100	0.076	Contact Map
2jifA	4	0.9974	100	0.077	Contact Map
3pfdA	4	0.9736	100	0.078	Contact Map
1ivhA	4	1	100	0.078	Contact Map
4irnA	4	0.9894	100	0.08	Contact Map
4p13A	4	0.9974	100	0.082	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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