GREMLIN Database
YWJB - Uncharacterized protein YwjB
UniProt: P45862 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 174 (170)
Sequences: 5600 (3823)
Seq/√Len: 293.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
134_V169_L4.1281.00
52_R56_E3.5551.00
122_M130_F3.1931.00
156_R172_V3.1651.00
7_L118_V2.9751.00
71_T88_T2.5501.00
93_G96_A2.5471.00
158_K172_V2.3881.00
129_E170_H2.3801.00
17_I115_A2.3751.00
75_F117_L2.3731.00
116_E120_D2.3151.00
3_R106_G2.3141.00
47_T73_Y2.3021.00
100_R104_E2.3021.00
95_R124_E2.2831.00
7_L127_I2.2331.00
4_K129_E2.2081.00
97_F100_R2.0731.00
144_P147_H2.0691.00
6_V108_N2.0561.00
46_D107_S2.0291.00
90_I97_F2.0151.00
14_D140_G1.9781.00
4_K108_N1.9741.00
20_E141_S1.9651.00
3_R105_K1.9511.00
129_E172_V1.8791.00
159_G170_H1.7881.00
76_T89_F1.7631.00
79_P89_F1.6911.00
13_L155_L1.6721.00
82_Y89_F1.6511.00
100_R103_Q1.5501.00
73_Y90_I1.5091.00
44_T108_N1.4811.00
19_K23_S1.4771.00
127_I130_F1.4561.00
76_T79_P1.4191.00
131_I170_H1.4121.00
92_E96_A1.3981.00
47_T71_T1.3861.00
18_A143_I1.3861.00
95_R99_A1.3461.00
99_A103_Q1.3341.00
36_N40_D1.3141.00
138_V155_L1.2961.00
80_D91_N1.2851.00
144_P148_E1.2791.00
19_K152_E1.2581.00
54_T113_G1.2541.00
75_F97_F1.2521.00
157_L169_L1.2501.00
23_S26_W1.2421.00
56_E60_V1.2421.00
39_S43_Q1.2381.00
31_E34_G1.2201.00
35_D39_S1.2181.00
5_T98_T1.2011.00
71_T104_E1.1921.00
53_S116_E1.1891.00
47_T109_I1.1821.00
75_F90_I1.1691.00
4_K172_V1.1651.00
9_I17_I1.1511.00
157_L167_V1.1321.00
96_A100_R1.1261.00
16_M144_P1.1071.00
57_H61_L1.1001.00
92_E100_R1.0961.00
131_I168_Q1.0841.00
130_F155_L1.0821.00
11_V134_V1.0811.00
10_A135_I1.0741.00
157_L160_T1.0701.00
119_N123_K1.0691.00
5_T102_K1.0551.00
96_A99_A1.0411.00
12_S139_L1.0301.00
11_V132_I1.0261.00
11_V17_I1.0071.00
98_T121_F1.0011.00
159_G162_Q1.0011.00
40_D43_Q0.9861.00
52_R77_G0.9721.00
133_T168_Q0.9681.00
73_Y104_E0.9541.00
82_Y87_V0.9501.00
122_M127_I0.9491.00
77_G116_E0.9481.00
123_K149_L0.9381.00
163_F166_A0.9371.00
22_G53_S0.9361.00
117_L120_D0.9271.00
6_V131_I0.9211.00
102_K109_I0.9191.00
60_V63_P0.9121.00
50_L58_V0.9111.00
41_F44_T0.9111.00
158_K170_H0.9021.00
94_A124_E0.9001.00
9_I115_A0.8981.00
29_E154_K0.8971.00
26_W29_E0.8941.00
49_I75_F0.8931.00
52_R79_P0.8771.00
19_K25_D0.8691.00
141_S148_E0.8651.00
119_N147_H0.8611.00
49_I98_T0.8531.00
37_G40_D0.8501.00
42_Y70_K0.8491.00
73_Y88_T0.8471.00
120_D124_E0.8441.00
167_V171_Y0.8431.00
37_G41_F0.8401.00
40_D44_T0.8401.00
55_Y59_K0.8391.00
157_L171_Y0.8351.00
41_F45_V0.8241.00
3_R47_T0.8241.00
46_D108_N0.8241.00
123_K148_E0.8091.00
115_A119_N0.8081.00
7_L114_G0.8061.00
41_F131_I0.8021.00
45_V110_W0.7990.99
77_G120_D0.7960.99
5_T121_F0.7950.99
111_I127_I0.7900.99
37_G168_Q0.7870.99
161_K168_Q0.7870.99
50_L114_G0.7860.99
123_K150_T0.7840.99
46_D105_K0.7810.99
125_D153_T0.7780.99
22_G143_I0.7700.99
26_W30_F0.7640.99
31_E165_Q0.7590.99
8_Y131_I0.7480.99
97_F101_L0.7450.99
81_S89_F0.7390.99
123_K151_N0.7350.99
163_F168_Q0.7320.99
135_I166_A0.7280.99
40_D161_K0.7280.99
52_R78_S0.7230.99
76_T80_D0.7230.99
118_V127_I0.7210.99
132_I145_L0.7150.99
13_L138_V0.7100.99
27_L30_F0.7090.99
48_V70_K0.7040.99
31_E164_G0.6970.99
3_R46_D0.6950.99
5_T111_I0.6880.98
154_K157_L0.6870.98
73_Y97_F0.6810.98
9_I118_V0.6770.98
129_E158_K0.6720.98
8_Y41_F0.6720.98
33_E36_N0.6700.98
49_I121_F0.6700.98
24_I57_H0.6680.98
19_K22_G0.6660.98
8_Y38_Y0.6650.98
92_E97_F0.6640.98
160_T167_V0.6620.98
7_L111_I0.6600.98
18_A23_S0.6510.98
75_F94_A0.6510.98
102_K106_G0.6480.98
46_D106_G0.6430.98
162_Q167_V0.6420.98
53_S56_E0.6400.98
83_Q87_V0.6370.97
58_V112_A0.6360.97
46_D109_I0.6360.97
93_G97_F0.6340.97
84_D114_G0.6320.97
77_G92_E0.6300.97
57_H60_V0.6260.97
84_D87_V0.6250.97
90_I93_G0.6250.97
25_D29_E0.6240.97
120_D123_K0.6200.97
79_P82_Y0.6170.97
9_I145_L0.6140.97
9_I114_G0.6090.97
8_Y110_W0.6080.97
59_K63_P0.6070.97
47_T106_G0.6010.96
149_L152_E0.5990.96
38_Y48_V0.5980.96
91_N97_F0.5980.96
155_L171_Y0.5920.96
10_A38_Y0.5910.96
40_D159_G0.5910.96
149_L153_T0.5900.96
37_G133_T0.5880.96
78_S82_Y0.5870.96
115_A143_I0.5870.96
73_Y106_G0.5830.96
121_F126_A0.5830.96
141_S150_T0.5830.96
56_E79_P0.5770.96
33_E164_G0.5760.95
48_V67_Y0.5710.95
94_A120_D0.5700.95
38_Y41_F0.5700.95
116_E119_N0.5680.95
31_E39_S0.5600.95
8_Y133_T0.5560.95
151_N154_K0.5530.94
65_F72_C0.5520.94
37_G131_I0.5520.94
88_T97_F0.5510.94
8_Y112_A0.5510.94
18_A22_G0.5500.94
83_Q89_F0.5500.94
59_K62_T0.5480.94
27_L135_I0.5460.94
42_Y45_V0.5420.94
78_S81_S0.5410.94
56_E59_K0.5400.94
101_L105_K0.5370.93
51_G54_T0.5370.93
138_V153_T0.5350.93
72_C86_H0.5330.93
12_S27_L0.5320.93
58_V63_P0.5320.93
58_V67_Y0.5310.93
41_F110_W0.5300.93
59_K84_D0.5290.93
93_G99_A0.5270.93
99_A124_E0.5250.93
90_I94_A0.5220.93
18_A115_A0.5220.93
72_C84_D0.5200.92
16_M143_I0.5160.92
138_V146_F0.5130.92
10_A27_L0.5110.92
33_E163_F0.5100.92
134_V167_V0.5090.92
90_I100_R0.5070.91
17_I143_I0.5070.91
119_N122_M0.5060.91
3_R102_K0.5050.91
34_G37_G0.5040.91
101_L109_I0.5030.91
125_D155_L0.5030.91
10_A114_G0.5030.91
12_S138_V0.5030.91
38_Y42_Y0.5020.91
48_V112_A0.5000.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3jtwA 2 0.9885 100 0.306 Contact Map
2gd9A 2 0.9655 100 0.334 Contact Map
2xw7A 2 0.9713 100 0.349 Contact Map
3kgyA 2 0.9828 100 0.356 Contact Map
3ky8A 2 0.9885 100 0.356 Contact Map
3qg2A 2 0.954 100 0.358 Contact Map
3zpgA 2 0.977 100 0.379 Contact Map
3ix9A 2 0.908 100 0.381 Contact Map
3hj3A 2 0.9425 100 0.385 Contact Map
3nrrA 2 0.931 100 0.385 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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