YWJA - BACSU - GREMLIN Contacts

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YWJA - Uncharacterized ABC transporter ATP-binding protein YwjA

UniProt:	P45861	Sequences: MLRQFFSYYKPYKTLFFLDFFSAIAGGLMELSFPLIVNYFIDTLLPGRDWGLIIATSIGLFAVYALSSALQYIVTYWGHMLGINIETDMRKSLFDHLQKLSFKFYDNNKTGTLMSKLTNDLMYIGEVAHHGPEDLFIAVMTILGAFGVMLFINWQLALLTFIIMPIVIWLALYFNKKMTKAFTTLNKDIGDFSARVENNIGGIRLVQAFGNEAFEKERFAVNNQRFRVTKLSSYKIMAKNGSISYMLTRFVTLFVLLCGTWFVIRGSLSYGEFVAFVLLTNVLFRPIDKINAIIEMYPRGIAGFKSYMELMETEPDIQDSPDSKDVSGLKGNIRYKHVSFGYDDHHNVLNDINLSIQAGETVAFVGPSGAGKSTLCSLLPRFYEASEGDITIDGISIKDMTLSSLRGQIGVVQQDVFLFSGTLRENIAYGRLGASEEDIWQAVKQAHLEELVHNMPDGLDTMIGERGVKLSGGQKQRLSIARMFLKNPSILILDEATSALDTETEAAIQKALQELSEGRTTLVIAHRLATIKDADRIVVVTNNGIEEQGRHQDLIEAGGLYSRLHQAQFGQMVHR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	575 (558)
Sequences:	52649 (37218)
Seq/√Len:	1575.6

ECOLI - MDLA MSBA MDLB CYDD CYDC YOJI YDDA ARAG PROV
BACSU - YWJA YHEH YFIC YGAD YHEI YKNU YFIB BMRA YKNV SUNT CYDD CYDC YVRA OPUAA OPUCA OPUBA
HALSA - Q9HSQ7 Q9HMX3 Q9HMW0 BTUDA
SULSO - Q97UJ9 Q97VF5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
449_E	459_L	4.477	1.00
334_R	355_S	4.350	1.00
360_E	536_R	4.289	1.00
357_Q	360_E	4.283	1.00
337_H	351_D	4.254	1.00
536_R	548_Q	3.988	1.00
421_G	425_E	3.961	1.00
551_H	561_Y	3.867	1.00
336_K	389_D	3.859	1.00
424_R	436_E	3.807	1.00
444_K	449_E	3.767	1.00
336_K	391_T	3.466	1.00
332_N	355_S	3.464	1.00
449_E	453_H	3.403	1.00
389_D	396_S	3.294	1.00
350_N	544_G	3.100	1.00
424_R	460_D	3.002	1.00
335_Y	338_V	2.985	1.00
424_R	428_A	2.965	1.00
435_S	438_D	2.901	1.00
558_G	562_S	2.895	1.00
562_S	566_Q	2.882	1.00
436_E	440_W	2.866	1.00
347_N	350_N	2.848	1.00
443_V	459_L	2.822	1.00
376_C	524_I	2.781	1.00
339_S	351_D	2.748	1.00
376_C	492_I	2.687	1.00
408_Q	489_S	2.650	1.00
334_R	391_T	2.543	1.00
547_E	557_A	2.537	1.00
441_Q	445_Q	2.509	1.00
332_N	357_Q	2.406	1.00
341_G	347_N	2.377	1.00
487_N	519_R	2.363	1.00
147_G	151_F	2.357	1.00
440_W	449_E	2.352	1.00
427_I	443_V	2.352	1.00
538_V	548_Q	2.351	1.00
356_I	362_V	2.348	1.00
550_R	553_D	2.332	1.00
381_R	384_E	2.330	1.00
457_D	461_T	2.328	1.00
401_T	404_S	2.298	1.00
42_D	271_G	2.284	1.00
410_G	488_P	2.270	1.00
431_R	438_D	2.268	1.00
547_E	559_G	2.259	1.00
339_S	387_E	2.240	1.00
339_S	347_N	2.236	1.00
424_R	439_I	2.234	1.00
547_E	558_G	2.231	1.00
361_T	534_A	2.141	1.00
354_L	538_V	2.129	1.00
332_N	358_A	2.111	1.00
440_W	444_K	2.095	1.00
541_T	560_L	2.090	1.00
8_Y	92_S	2.036	1.00
448_L	451_L	2.004	1.00
427_I	439_I	2.004	1.00
335_Y	354_L	2.001	1.00
513_Q	533_D	1.987	1.00
505_E	527_R	1.973	1.00
356_I	522_L	1.968	1.00
42_D	269_S	1.940	1.00
438_D	487_N	1.937	1.00
384_E	398_K	1.936	1.00
12_Y	88_D	1.935	1.00
337_H	353_N	1.923	1.00
341_G	386_S	1.905	1.00
308_M	312_E	1.894	1.00
188_D	225_R	1.875	1.00
96_H	315_P	1.873	1.00
440_W	453_H	1.871	1.00
549_G	553_D	1.870	1.00
331_G	393_D	1.861	1.00
54_I	58_I	1.861	1.00
10_K	13_K	1.826	1.00
442_A	446_A	1.782	1.00
153_N	262_F	1.775	1.00
362_V	536_R	1.766	1.00
428_A	439_I	1.754	1.00
362_V	538_V	1.730	1.00
375_L	540_V	1.727	1.00
546_E	560_L	1.727	1.00
441_Q	444_K	1.725	1.00
428_A	436_E	1.696	1.00
538_V	545_I	1.687	1.00
436_E	460_D	1.674	1.00
363_A	534_A	1.660	1.00
541_T	546_E	1.650	1.00
447_H	507_A	1.650	1.00
211_N	214_F	1.648	1.00
360_E	535_D	1.641	1.00
500_L	508_I	1.635	1.00
506_A	510_K	1.633	1.00
120_D	306_S	1.628	1.00
361_T	523_V	1.626	1.00
555_I	565_H	1.616	1.00
333_I	522_L	1.597	1.00
330_K	393_D	1.595	1.00
464_G	469_K	1.593	1.00
58_I	62_A	1.590	1.00
427_I	485_L	1.575	1.00
396_S	399_D	1.567	1.00
445_Q	514_E	1.565	1.00
319_D	401_T	1.554	1.00
364_F	538_V	1.546	1.00
183_T	305_K	1.545	1.00
450_E	453_H	1.528	1.00
443_V	452_V	1.527	1.00
440_W	459_L	1.522	1.00
332_N	393_D	1.512	1.00
463_I	470_L	1.510	1.00
99_K	315_P	1.509	1.00
553_D	557_A	1.504	1.00
438_D	441_Q	1.503	1.00
364_F	375_L	1.498	1.00
547_E	562_S	1.484	1.00
349_L	352_I	1.472	1.00
150_L	157_A	1.470	1.00
257_L	261_W	1.460	1.00
434_A	485_L	1.458	1.00
525_A	530_T	1.451	1.00
532_K	552_Q	1.449	1.00
38_N	275_A	1.445	1.00
457_D	462_M	1.444	1.00
55_A	59_G	1.434	1.00
191_D	225_R	1.427	1.00
437_E	440_W	1.424	1.00
357_Q	536_R	1.417	1.00
96_H	100_L	1.414	1.00
261_W	265_R	1.406	1.00
443_V	449_E	1.404	1.00
340_F	374_T	1.400	1.00
195_R	222_N	1.396	1.00
510_K	514_E	1.394	1.00
380_P	411_V	1.391	1.00
560_L	563_R	1.382	1.00
367_P	541_T	1.364	1.00
338_V	385_A	1.364	1.00
335_Y	379_L	1.359	1.00
514_E	517_E	1.355	1.00
378_L	390_I	1.351	1.00
340_F	378_L	1.342	1.00
420_S	462_M	1.340	1.00
552_Q	556_E	1.339	1.00
436_E	439_I	1.338	1.00
351_D	544_G	1.332	1.00
188_D	229_T	1.331	1.00
329_L	393_D	1.327	1.00
150_L	154_W	1.326	1.00
438_D	485_L	1.325	1.00
34_P	279_L	1.325	1.00
451_L	474_Q	1.318	1.00
184_T	229_T	1.304	1.00
410_G	483_M	1.292	1.00
177_K	180_K	1.284	1.00
340_F	383_Y	1.282	1.00
331_G	358_A	1.267	1.00
22_S	70_L	1.258	1.00
215_E	429_Y	1.255	1.00
188_D	191_D	1.250	1.00
363_A	531_I	1.249	1.00
367_P	560_L	1.248	1.00
11_P	88_D	1.236	1.00
336_K	353_N	1.235	1.00
96_H	311_M	1.230	1.00
169_W	173_Y	1.228	1.00
395_I	399_D	1.227	1.00
339_S	350_N	1.227	1.00
368_S	504_T	1.214	1.00
437_E	441_Q	1.207	1.00
428_A	434_A	1.203	1.00
379_L	522_L	1.203	1.00
423_L	478_L	1.202	1.00
156_L	276_F	1.201	1.00
455_M	461_T	1.200	1.00
332_N	394_G	1.196	1.00
443_V	448_L	1.194	1.00
149_M	276_F	1.194	1.00
445_Q	484_F	1.191	1.00
516_S	521_T	1.190	1.00
269_S	272_E	1.187	1.00
385_A	397_I	1.187	1.00
31_L	144_G	1.186	1.00
451_L	455_M	1.183	1.00
362_V	522_L	1.176	1.00
262_F	267_S	1.171	1.00
448_L	452_V	1.165	1.00
51_G	55_A	1.165	1.00
199_N	215_E	1.165	1.00
358_A	489_S	1.164	1.00
91_K	95_D	1.164	1.00
354_L	375_L	1.162	1.00
476_Q	498_S	1.160	1.00
431_R	434_A	1.153	1.00
217_E	221_V	1.152	1.00
207_Q	212_E	1.151	1.00
454_N	474_Q	1.149	1.00
202_G	417_F	1.141	1.00
435_S	485_L	1.136	1.00
224_Q	228_V	1.134	1.00
440_W	443_V	1.134	1.00
352_I	375_L	1.132	1.00
537_I	551_H	1.131	1.00
213_A	217_E	1.127	1.00
330_K	358_A	1.117	1.00
470_L	478_L	1.116	1.00
347_N	386_S	1.110	1.00
395_I	400_M	1.110	1.00
453_H	458_G	1.108	1.00
464_G	467_G	1.107	1.00
402_L	406_R	1.106	1.00
106_D	383_Y	1.106	1.00
442_A	484_F	1.105	1.00
38_N	42_D	1.100	1.00
108_N	112_T	1.100	1.00
335_Y	390_I	1.099	1.00
112_T	190_G	1.088	1.00
93_L	310_L	1.088	1.00
356_I	520_T	1.083	1.00
447_H	504_T	1.083	1.00
25_A	70_L	1.082	1.00
191_D	222_N	1.079	1.00
95_D	99_K	1.078	1.00
258_C	262_F	1.073	1.00
304_F	308_M	1.070	1.00
181_A	232_S	1.065	1.00
551_H	555_I	1.061	1.00
96_H	99_K	1.058	1.00
558_G	566_Q	1.057	1.00
361_T	521_T	1.057	1.00
450_E	454_N	1.056	1.00
337_H	387_E	1.053	1.00
412_V	483_M	1.044	1.00
109_K	112_T	1.043	1.00
35_L	39_Y	1.042	1.00
335_Y	375_L	1.039	1.00
446_A	481_A	1.039	1.00
483_M	491_L	1.036	1.00
163_I	251_V	1.034	1.00
221_V	225_R	1.032	1.00
80_M	84_N	1.032	1.00
215_E	218_R	1.029	1.00
333_I	379_L	1.027	1.00
539_V	560_L	1.025	1.00
525_A	531_I	1.024	1.00
88_D	92_S	1.024	1.00
404_S	407_G	1.024	1.00
523_V	534_A	1.024	1.00
232_S	235_K	1.023	1.00
447_H	510_K	1.022	1.00
227_R	231_L	1.020	1.00
416_V	479_S	1.015	1.00
195_R	218_R	1.014	1.00
378_L	385_A	1.013	1.00
15_L	80_M	1.012	1.00
452_V	459_L	1.010	1.00
319_D	402_L	1.010	1.00
219_F	223_N	1.003	1.00
425_E	428_A	1.002	1.00
36_I	56_T	1.002	1.00
447_H	511_A	1.000	1.00
392_I	405_L	0.998	1.00
155_Q	267_S	0.997	1.00
342_Y	348_V	0.992	1.00
22_S	73_I	0.992	1.00
17_F	21_F	0.986	1.00
38_N	272_E	0.984	1.00
491_L	519_R	0.983	1.00
495_E	526_H	0.983	1.00
259_G	273_F	0.983	1.00
143_L	147_G	0.981	1.00
489_S	519_R	0.980	1.00
218_R	222_N	0.976	1.00
507_A	510_K	0.975	1.00
347_N	387_E	0.975	1.00
19_D	78_G	0.971	1.00
123_Y	303_G	0.970	1.00
106_D	377_S	0.964	1.00
173_Y	177_K	0.960	1.00
206_V	215_E	0.959	1.00
447_H	514_E	0.959	1.00
441_Q	487_N	0.955	1.00
368_S	477_R	0.954	1.00
158_L	162_I	0.951	1.00
214_F	218_R	0.951	1.00
360_E	548_Q	0.950	1.00
334_R	394_G	0.950	1.00
154_W	158_L	0.948	1.00
390_I	397_I	0.946	1.00
211_N	215_E	0.944	1.00
338_V	378_L	0.942	1.00
184_T	188_D	0.940	1.00
472_G	477_R	0.937	1.00
363_A	525_A	0.936	1.00
457_D	460_D	0.932	1.00
370_A	540_V	0.930	1.00
87_T	91_K	0.930	1.00
540_V	545_I	0.927	1.00
439_I	459_L	0.927	1.00
503_E	507_A	0.925	1.00
424_R	440_W	0.924	1.00
39_Y	43_T	0.923	1.00
373_S	377_S	0.922	1.00
55_A	58_I	0.921	1.00
442_A	485_L	0.919	1.00
183_T	187_K	0.919	1.00
463_I	469_K	0.918	1.00
101_S	316_D	0.917	1.00
381_R	402_L	0.913	1.00
22_S	77_W	0.911	1.00
104_F	108_N	0.911	1.00
152_I	272_E	0.911	1.00
553_D	556_E	0.909	1.00
220_A	224_Q	0.909	1.00
301_I	305_K	0.909	1.00
444_K	453_H	0.907	1.00
224_Q	227_R	0.907	1.00
341_G	348_V	0.906	1.00
527_R	530_T	0.904	1.00
351_D	387_E	0.903	1.00
260_T	264_I	0.902	1.00
334_R	353_N	0.901	1.00
445_Q	515_L	0.899	1.00
159_L	258_C	0.898	1.00
424_R	459_L	0.898	1.00
13_K	17_F	0.896	1.00
361_T	513_Q	0.889	1.00
404_S	408_Q	0.889	1.00
116_K	309_E	0.889	1.00
170_L	243_I	0.886	1.00
400_M	405_L	0.885	1.00
439_I	485_L	0.884	1.00
434_A	438_D	0.881	1.00
92_S	96_H	0.881	1.00
62_A	66_L	0.879	1.00
14_T	18_L	0.877	1.00
93_L	117_L	0.876	1.00
380_P	409_I	0.875	1.00
177_K	236_I	0.875	1.00
363_A	537_I	0.874	1.00
12_Y	84_N	0.873	1.00
336_K	355_S	0.872	1.00
563_R	566_Q	0.872	1.00
412_V	480_I	0.870	1.00
184_T	232_S	0.868	1.00
389_D	398_K	0.867	1.00
120_D	303_G	0.866	1.00
453_H	459_L	0.865	1.00
181_A	229_T	0.864	1.00
480_I	493_L	0.863	1.00
214_F	217_E	0.863	1.00
545_I	548_Q	0.862	1.00
103_K	316_D	0.862	1.00
380_P	492_I	0.862	1.00
225_R	229_T	0.860	1.00
333_I	392_I	0.859	1.00
385_A	398_K	0.856	1.00
392_I	490_I	0.856	1.00
559_G	562_S	0.848	1.00
204_R	377_S	0.847	1.00
464_G	468_V	0.845	1.00
497_T	508_I	0.845	1.00
216_K	220_A	0.845	1.00
361_T	516_S	0.845	1.00
343_D	346_H	0.845	1.00
403_S	407_G	0.843	1.00
146_F	157_A	0.843	1.00
218_R	221_V	0.841	1.00
217_E	220_A	0.841	1.00
149_M	157_A	0.839	1.00
358_A	393_D	0.835	1.00
177_K	181_A	0.833	1.00
491_L	516_S	0.831	1.00
263_V	268_L	0.830	1.00
317_I	384_E	0.830	1.00
328_G	393_D	0.830	1.00
326_V	400_M	0.829	1.00
448_L	454_N	0.827	1.00
155_Q	262_F	0.825	1.00
222_N	225_R	0.825	1.00
19_D	81_L	0.824	1.00
541_T	544_G	0.823	1.00
463_I	467_G	0.822	1.00
103_K	107_N	0.821	1.00
29_M	70_L	0.821	1.00
397_I	405_L	0.819	1.00
29_M	66_L	0.819	1.00
505_E	509_Q	0.818	1.00
385_A	390_I	0.817	1.00
100_L	313_T	0.816	1.00
168_I	172_L	0.815	1.00
341_G	344_D	0.814	1.00
418_L	478_L	0.814	1.00
352_I	545_I	0.814	1.00
213_A	216_K	0.812	1.00
307_Y	311_M	0.811	1.00
427_I	478_L	0.809	1.00
341_G	345_H	0.809	1.00
418_L	475_K	0.809	1.00
419_F	426_N	0.808	1.00
180_K	184_T	0.808	1.00
229_T	232_S	0.808	1.00
446_A	477_R	0.802	1.00
185_L	230_K	0.802	1.00
52_L	55_A	0.801	1.00
488_P	519_R	0.801	1.00
39_Y	56_T	0.800	1.00
391_T	394_G	0.800	1.00
324_K	395_I	0.799	1.00
36_I	63_V	0.798	1.00
445_Q	449_E	0.796	1.00
314_E	318_Q	0.795	1.00
151_F	154_W	0.792	1.00
172_L	176_K	0.790	1.00
205_L	209_F	0.789	1.00
326_V	329_L	0.787	1.00
558_G	563_R	0.785	1.00
148_V	152_I	0.785	1.00
339_S	386_S	0.784	1.00
35_L	148_V	0.783	1.00
112_T	116_K	0.782	1.00
422_T	425_E	0.781	1.00
93_L	307_Y	0.780	1.00
324_K	399_D	0.780	1.00
69_A	73_I	0.777	1.00
96_H	314_E	0.774	1.00
409_I	490_I	0.774	1.00
39_Y	42_D	0.773	1.00
407_G	486_K	0.772	1.00
23_A	137_I	0.769	1.00
263_V	273_F	0.769	1.00
427_I	459_L	0.767	1.00
36_I	59_G	0.766	1.00
451_L	454_N	0.764	1.00
262_F	265_R	0.761	1.00
127_V	300_G	0.760	1.00
400_M	404_S	0.759	1.00
101_S	317_I	0.756	1.00
203_I	207_Q	0.756	1.00
443_V	446_A	0.755	1.00
192_F	226_F	0.753	1.00
491_L	521_T	0.752	1.00
150_L	161_F	0.750	1.00
28_L	32_S	0.748	1.00
123_Y	299_R	0.748	1.00
415_D	475_K	0.748	1.00
328_G	489_S	0.747	1.00
138_A	289_K	0.746	1.00
231_L	235_K	0.746	1.00
428_A	432_L	0.745	1.00
148_V	151_F	0.744	1.00
113_L	310_L	0.744	1.00
555_I	562_S	0.744	1.00
188_D	222_N	0.743	1.00
365_V	539_V	0.742	1.00
326_V	404_S	0.742	1.00
155_Q	158_L	0.742	1.00
144_G	147_G	0.742	1.00
448_L	478_L	0.742	1.00
341_G	346_H	0.741	1.00
43_T	52_L	0.741	1.00
35_L	38_N	0.740	1.00
477_R	504_T	0.739	1.00
428_A	433_G	0.739	1.00
246_M	250_F	0.736	1.00
333_I	490_I	0.735	1.00
202_G	205_L	0.735	1.00
29_M	63_V	0.734	1.00
162_I	165_P	0.734	1.00
139_V	143_L	0.734	1.00
431_R	487_N	0.733	1.00
15_L	84_N	0.732	1.00
97_L	105_Y	0.731	1.00
127_V	297_Y	0.731	1.00
152_I	275_A	0.730	1.00
551_H	565_H	0.728	1.00
15_L	77_W	0.727	1.00
455_M	470_L	0.727	1.00
476_Q	499_A	0.725	1.00
41_I	274_V	0.722	1.00
58_I	61_F	0.722	1.00
57_S	61_F	0.721	1.00
428_A	431_R	0.720	1.00
350_N	542_N	0.719	1.00
228_V	232_S	0.719	1.00
331_G	520_T	0.719	1.00
271_G	275_A	0.718	1.00
56_T	59_G	0.718	1.00
27_G	140_M	0.717	1.00
225_R	228_V	0.717	1.00
184_T	187_K	0.716	1.00
72_Y	76_Y	0.715	1.00
323_S	326_V	0.712	1.00
153_N	157_A	0.711	1.00
368_S	495_E	0.710	1.00
59_G	62_A	0.710	1.00
447_H	450_E	0.709	1.00
157_A	276_F	0.707	1.00
448_L	459_L	0.706	1.00
116_K	120_D	0.704	1.00
42_D	45_L	0.701	1.00
431_R	486_K	0.700	1.00
92_S	95_D	0.698	1.00
145_A	283_L	0.696	1.00
145_A	282_V	0.696	1.00
472_G	499_A	0.696	1.00
359_G	520_T	0.695	1.00
497_T	505_E	0.694	1.00
377_S	383_Y	0.694	1.00
21_F	25_A	0.694	1.00
176_K	180_K	0.694	1.00
391_T	396_S	0.693	1.00
100_L	315_P	0.693	1.00
66_L	70_L	0.692	1.00
325_D	404_S	0.688	1.00
385_A	389_D	0.687	1.00
25_A	66_L	0.686	1.00
346_H	350_N	0.685	1.00
405_L	409_I	0.684	1.00
362_V	548_Q	0.683	1.00
86_E	125_G	0.683	1.00
305_K	309_E	0.682	1.00
92_S	311_M	0.681	1.00
505_E	530_T	0.680	1.00
18_L	77_W	0.680	1.00
557_A	560_L	0.679	1.00
436_E	459_L	0.677	1.00
420_S	464_G	0.677	1.00
508_I	511_A	0.675	1.00
361_T	533_D	0.674	1.00
445_Q	511_A	0.673	1.00
342_Y	374_T	0.673	1.00
547_E	560_L	0.671	1.00
536_R	550_R	0.670	1.00
359_G	518_G	0.670	1.00
93_L	311_M	0.670	1.00
552_Q	555_I	0.669	1.00
262_F	266_G	0.668	1.00
356_I	360_E	0.667	1.00
10_K	14_T	0.666	1.00
169_W	172_L	0.665	1.00
153_N	268_L	0.665	1.00
35_L	152_I	0.664	1.00
181_A	184_T	0.663	1.00
95_D	216_K	0.663	1.00
258_C	261_W	0.662	1.00
376_C	522_L	0.661	1.00
52_L	56_T	0.661	1.00
109_K	194_A	0.660	1.00
456_P	461_T	0.660	1.00
349_L	540_V	0.660	1.00
378_L	383_Y	0.659	1.00
12_Y	15_L	0.658	1.00
323_S	404_S	0.658	1.00
50_W	54_I	0.657	1.00
423_L	452_V	0.657	1.00
547_E	554_L	0.656	1.00
147_G	150_L	0.655	1.00
43_T	46_P	0.654	1.00
102_F	106_D	0.653	1.00
300_G	303_G	0.653	1.00
86_E	90_R	0.651	1.00
480_I	484_F	0.648	1.00
186_N	189_I	0.648	1.00
135_L	139_V	0.647	1.00
536_R	553_D	0.646	1.00
325_D	401_T	0.645	1.00
324_K	327_S	0.645	1.00
120_D	186_N	0.644	1.00
330_K	520_T	0.644	1.00
190_G	306_S	0.643	1.00
26_G	71_Q	0.643	1.00
153_N	156_L	0.642	1.00
259_G	263_V	0.641	1.00
531_I	534_A	0.641	1.00
500_L	504_T	0.639	1.00
115_S	193_S	0.639	1.00
364_F	522_L	0.638	1.00
509_Q	530_T	0.637	1.00
89_M	121_L	0.637	1.00
436_E	443_V	0.635	1.00
471_S	474_Q	0.635	1.00
480_I	508_I	0.633	1.00
438_D	442_A	0.632	1.00
547_E	555_I	0.630	1.00
421_G	462_M	0.630	1.00
560_L	564_L	0.629	1.00
317_I	381_R	0.629	1.00
335_Y	352_I	0.627	1.00
14_T	17_F	0.627	1.00
492_I	522_L	0.627	1.00
145_A	279_L	0.626	1.00
93_L	121_L	0.626	1.00
509_Q	525_A	0.626	1.00
392_I	397_I	0.626	1.00
124_I	304_F	0.626	1.00
84_N	87_T	0.625	1.00
285_R	289_K	0.625	1.00
232_S	236_I	0.622	1.00
96_H	313_T	0.621	1.00
505_E	529_A	0.621	1.00
79_H	130_H	0.619	1.00
490_I	520_T	0.618	1.00
420_S	469_K	0.617	1.00
441_Q	515_L	0.617	1.00
329_L	408_Q	0.616	1.00
17_F	20_F	0.615	1.00
547_E	563_R	0.614	1.00
42_D	46_P	0.614	1.00
344_D	386_S	0.614	1.00
440_W	452_V	0.614	1.00
234_Y	238_A	0.614	1.00
352_I	540_V	0.613	1.00
31_L	34_P	0.613	1.00
322_D	399_D	0.613	1.00
511_A	514_E	0.613	1.00
160_T	280_T	0.612	1.00
548_Q	553_D	0.612	1.00
557_A	562_S	0.611	1.00
23_A	74_V	0.611	1.00
338_V	388_G	0.609	1.00
112_T	306_S	0.608	1.00
516_S	519_R	0.607	1.00
442_A	481_A	0.607	1.00
376_C	411_V	0.606	1.00
173_Y	176_K	0.606	1.00
446_A	484_F	0.604	1.00
228_V	231_L	0.604	1.00
51_G	54_I	0.603	1.00
245_Y	288_D	0.603	1.00
346_H	542_N	0.602	1.00
182_F	233_S	0.601	1.00
415_D	466_R	0.601	1.00
418_L	463_I	0.601	1.00
156_L	262_F	0.601	1.00
65_A	69_A	0.601	1.00
126_E	296_M	0.600	1.00
551_H	554_L	0.600	1.00
393_D	489_S	0.600	1.00
502_T	505_E	0.599	1.00
54_I	57_S	0.599	1.00
477_R	500_L	0.599	1.00
238_A	242_S	0.599	1.00
410_G	486_K	0.598	1.00
509_Q	533_D	0.597	1.00
318_Q	401_T	0.597	1.00
165_P	169_W	0.595	1.00
354_L	545_I	0.594	1.00
104_F	113_L	0.594	1.00
447_H	508_I	0.593	1.00
239_K	242_S	0.591	1.00
340_F	348_V	0.591	1.00
341_G	387_E	0.590	1.00
87_T	223_N	0.590	1.00
412_V	493_L	0.589	1.00
32_S	63_V	0.588	1.00
338_V	390_I	0.587	1.00
439_I	443_V	0.586	1.00
122_M	125_G	0.585	1.00
101_S	104_F	0.585	1.00
402_L	405_L	0.584	1.00
186_N	302_A	0.583	1.00
134_D	289_K	0.583	1.00
12_Y	85_I	0.582	1.00
446_A	480_I	0.582	1.00
137_I	141_T	0.581	1.00
115_S	189_I	0.580	1.00
126_E	130_H	0.580	1.00
546_E	558_G	0.580	1.00
187_K	191_D	0.578	1.00
345_H	348_V	0.578	1.00
501_D	504_T	0.578	1.00
357_Q	362_V	0.577	1.00
268_L	272_E	0.577	1.00
174_F	240_N	0.576	1.00
205_L	208_A	0.576	1.00
458_G	461_T	0.576	1.00
452_V	455_M	0.576	1.00
356_I	361_T	0.575	1.00
431_R	485_L	0.573	1.00
255_V	280_T	0.573	1.00
422_T	460_D	0.573	1.00
138_A	142_I	0.572	1.00
532_K	551_H	0.572	1.00
510_K	513_Q	0.571	1.00
428_A	443_V	0.571	1.00
170_L	247_L	0.571	1.00
38_N	271_G	0.571	1.00
107_N	343_D	0.570	1.00
195_R	199_N	0.570	1.00
26_G	70_L	0.570	1.00
352_I	538_V	0.569	1.00
542_N	546_E	0.569	1.00
79_H	83_I	0.569	1.00
444_K	459_L	0.569	1.00
25_A	29_M	0.569	1.00
338_V	353_N	0.568	1.00
261_W	264_I	0.568	1.00
426_N	478_L	0.568	1.00
94_F	98_Q	0.567	1.00
89_M	124_I	0.566	1.00
473_G	501_D	0.566	1.00
537_I	550_R	0.564	1.00
368_S	525_A	0.564	1.00
45_L	48_R	0.564	1.00
413_Q	416_V	0.563	1.00
414_Q	472_G	0.562	1.00
76_Y	80_M	0.561	1.00
329_L	358_A	0.560	1.00
83_I	86_E	0.560	1.00
431_R	435_S	0.560	1.00
121_L	307_Y	0.559	1.00
385_A	396_S	0.559	1.00
68_S	72_Y	0.557	1.00
344_D	347_N	0.556	1.00
155_Q	258_C	0.555	1.00
185_L	233_S	0.555	1.00
439_I	442_A	0.554	1.00
368_S	500_L	0.554	1.00
555_I	566_Q	0.554	1.00
423_L	463_I	0.554	1.00
377_S	411_V	0.552	1.00
184_T	225_R	0.551	1.00
102_F	382_F	0.551	1.00
30_E	67_S	0.550	1.00
323_S	401_T	0.550	1.00
539_V	547_E	0.549	1.00
260_T	263_V	0.549	1.00
484_F	515_L	0.549	1.00
428_A	485_L	0.549	1.00
331_G	489_S	0.549	1.00
242_S	246_M	0.548	1.00
195_R	215_E	0.548	1.00
350_N	353_N	0.547	1.00
82_G	129_H	0.547	1.00
347_N	351_D	0.547	1.00
395_I	404_S	0.547	1.00
250_F	254_F	0.546	1.00
142_I	146_F	0.546	1.00
115_S	119_N	0.546	1.00
392_I	400_M	0.545	1.00
181_A	233_S	0.544	1.00
444_K	450_E	0.544	1.00
357_Q	520_T	0.543	1.00
467_G	475_K	0.542	1.00
115_S	190_G	0.540	1.00
35_L	275_A	0.539	1.00
110_T	114_M	0.538	1.00
117_L	121_L	0.537	1.00
364_F	524_I	0.537	1.00
59_G	63_V	0.537	1.00
303_G	306_S	0.536	1.00
339_S	349_L	0.535	1.00
322_D	401_T	0.535	1.00
168_I	171_A	0.534	1.00
373_S	376_C	0.534	1.00
364_F	540_V	0.533	1.00
160_T	283_L	0.531	1.00
27_G	31_L	0.531	1.00
365_V	531_I	0.531	1.00
189_I	193_S	0.530	1.00
443_V	481_A	0.530	1.00
449_E	452_V	0.528	1.00
484_F	511_A	0.528	1.00
8_Y	89_M	0.528	1.00
497_T	500_L	0.527	1.00
49_D	52_L	0.526	1.00
239_K	243_I	0.525	1.00
522_L	538_V	0.524	1.00
493_L	496_A	0.523	1.00
268_L	273_F	0.523	1.00
509_Q	513_Q	0.523	1.00
12_Y	81_L	0.522	1.00
116_K	306_S	0.522	1.00
374_T	383_Y	0.522	1.00
166_I	169_W	0.522	1.00
355_S	548_Q	0.522	1.00
27_G	30_E	0.521	1.00
73_I	77_W	0.521	1.00
11_P	14_T	0.521	1.00
555_I	558_G	0.520	1.00
329_L	392_I	0.520	1.00
36_I	39_Y	0.518	1.00
427_I	430_G	0.518	1.00
509_Q	523_V	0.518	1.00
206_V	212_E	0.518	1.00
316_D	406_R	0.518	1.00
151_F	155_Q	0.517	1.00
149_M	160_T	0.517	1.00
44_L	52_L	0.517	1.00
249_R	253_L	0.516	1.00
539_V	546_E	0.516	1.00
86_E	121_L	0.516	1.00
11_P	92_S	0.516	1.00
111_G	194_A	0.516	1.00
98_Q	101_S	0.514	1.00
146_F	150_L	0.514	1.00
412_V	496_A	0.513	1.00
264_I	267_S	0.513	1.00
314_E	317_I	0.513	1.00
401_T	405_L	0.513	1.00
477_R	499_A	0.513	1.00
504_T	508_I	0.512	1.00
119_N	186_N	0.511	1.00
355_S	358_A	0.511	1.00
504_T	507_A	0.510	1.00
423_L	448_L	0.510	1.00
70_L	73_I	0.510	1.00
329_L	332_N	0.509	1.00
154_W	157_A	0.509	1.00
356_I	538_V	0.508	1.00
231_L	234_Y	0.508	1.00
61_F	65_A	0.507	1.00
511_A	515_L	0.507	1.00
324_K	328_G	0.507	1.00
396_S	400_M	0.506	1.00
490_I	522_L	0.506	1.00
20_F	23_A	0.506	1.00
496_A	523_V	0.506	1.00
548_Q	557_A	0.505	1.00
166_I	170_L	0.505	1.00
561_Y	564_L	0.505	1.00
192_F	196_V	0.504	1.00
148_V	279_L	0.504	1.00
40_F	56_T	0.504	1.00
374_T	378_L	0.504	1.00
272_E	275_A	0.503	1.00
75_T	79_H	0.503	1.00
523_V	531_I	0.503	1.00
541_T	563_R	0.503	1.00
130_H	134_D	0.502	1.00
185_L	229_T	0.502	1.00
253_L	257_L	0.500	1.00
33_F	37_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.9704	100	0.078	Contact Map
4a82A	2	0.9913	100	0.099	Contact Map
4q4hB	1	0.9896	100	0.135	Contact Map
4f4cA	1	0.9704	100	0.142	Contact Map
3b5xA	2	0.9878	100	0.146	Contact Map
3b60A	2	0.9878	100	0.147	Contact Map
4q4hA	1	0.9896	100	0.153	Contact Map
3zdqA	2	0.9687	100	0.153	Contact Map
4mrsA	2	1	100	0.157	Contact Map
4q9hA	1	0.9896	100	0.164	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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