PRPD - BACSU - GREMLIN Contacts

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PRPD - 2-methylcitrate dehydratase

UniProt:	P45859	Sequences: MPKTDRVIEEITDYVLEKEITSAEAYTTAGHVLLDTLGCGILALRYPECTKLLGPIVPGTTVPNGSKVPGTSYVLDPVRAAFNIGCMIRWLDYNDTWLAAEWGHPSDNLGGILAAADYVSRVRLSEGKEPLTVRDVLEMMIKAHEIQGVLALENSLNRVGLDHVLFVKVATTAVAAKLLGGGREEIKNALSNAWIDNAALRTYRHSPNTGSRKSWAAGDATSRGVHLALMSLKGEMGYPTALSAPGWGFQDVLFNKKEIKLARPLDAYVMENVLFKVSYPAEFHAQTAAESAVILHPQVKNRIDEIDRVVIRTHESAIRIIDKKGPLHNPADRDHCLQYITAIGLLFGDITAQHYEAETANDPRIDKLRDKMEVTENKTYTEDYLKPDKRSISNAVQVHFKDGTSTEMVECEFPLGHRFRREEAVPKLLEKFSDNLKTHFPDKQHKHIYERCTSYETLQTMRVNEFVDMFCM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	472 (434)
Sequences:	2714 (1869)
Seq/√Len:	89.7

ECOLI - PRPD
BACSU - PRPD YXEQ
SULSO - Q97VN3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
176_A	186_I	5.470	1.00
182_G	185_E	4.155	1.00
308_R	373_E	3.909	1.00
307_D	401_K	3.883	1.00
67_K	117_D	3.871	1.00
13_D	183_R	3.780	1.00
132_T	135_D	3.364	1.00
30_G	456_E	3.214	1.00
415_L	427_K	3.112	1.00
397_Q	407_E	3.075	1.00
310_V	375_T	2.949	1.00
292_A	341_T	2.784	1.00
38_G	432_F	2.774	1.00
307_D	399_H	2.726	1.00
312_R	377_N	2.697	1.00
310_V	397_Q	2.645	1.00
31_H	425_V	2.608	1.00
400_F	406_T	2.582	1.00
305_E	401_K	2.551	1.00
367_K	371_K	2.548	1.00
139_M	178_L	2.541	1.00
312_R	395_A	2.491	1.00
308_R	399_H	2.440	1.00
293_V	344_G	2.440	1.00
27_T	425_V	2.422	1.00
347_F	354_H	2.422	1.00
189_A	231_S	2.421	1.00
147_Q	170_A	2.399	1.00
310_V	373_E	2.395	1.00
224_G	228_A	2.359	1.00
34_L	449_Y	2.323	1.00
29_A	141_I	2.312	1.00
399_H	405_S	2.285	1.00
395_A	410_E	2.270	1.00
21_T	141_I	2.251	1.00
25_A	271_E	2.244	1.00
179_L	229_L	2.214	1.00
119_V	131_L	2.201	1.00
433_S	446_K	2.190	1.00
281_A	285_A	2.150	1.00
115_A	175_A	2.118	1.00
33_L	140_M	2.094	1.00
112_I	174_V	2.051	1.00
310_V	399_H	2.043	1.00
115_A	225_V	2.033	1.00
454_S	457_T	2.019	1.00
112_I	136_V	2.010	1.00
424_A	427_K	2.008	1.00
138_E	177_K	2.001	1.00
36_T	88_I	1.997	1.00
429_L	453_T	1.995	1.00
29_A	137_L	1.898	1.00
312_R	397_Q	1.887	1.00
349_D	354_H	1.885	1.00
54_G	233_K	1.875	1.00
22_S	25_A	1.860	1.00
433_S	445_H	1.856	1.00
172_T	189_A	1.838	1.00
302_R	305_E	1.816	1.00
311_I	341_T	1.792	1.00
173_A	190_L	1.788	1.00
18_K	26_Y	1.759	1.00
24_E	271_E	1.745	1.00
18_K	134_R	1.741	1.00
156_L	165_L	1.732	1.00
432_F	436_L	1.723	1.00
446_K	450_E	1.701	1.00
115_A	179_L	1.691	1.00
312_R	375_T	1.679	1.00
192_N	212_R	1.679	1.00
88_I	107_D	1.662	1.00
16_L	183_R	1.654	1.00
347_F	362_D	1.643	1.00
301_N	400_F	1.633	1.00
109_L	140_M	1.625	1.00
438_T	441_P	1.621	1.00
400_F	404_T	1.612	1.00
150_L	169_V	1.606	1.00
34_L	452_C	1.603	1.00
289_A	344_G	1.582	1.00
14_Y	268_Y	1.556	1.00
143_A	174_V	1.546	1.00
179_L	228_A	1.543	1.00
49_C	87_M	1.536	1.00
194_W	241_A	1.535	1.00
429_L	449_Y	1.530	1.00
19_E	134_R	1.518	1.00
433_S	449_Y	1.517	1.00
347_F	359_T	1.515	1.00
135_D	138_E	1.512	1.00
26_Y	30_G	1.511	1.00
41_I	436_L	1.509	1.00
96_T	274_L	1.506	1.00
397_Q	405_S	1.495	1.00
202_T	245_P	1.493	1.00
135_D	177_K	1.490	1.00
169_V	190_L	1.478	1.00
339_Y	369_R	1.478	1.00
296_H	348_G	1.465	0.99
66_S	80_A	1.459	0.99
77_P	81_A	1.459	0.99
133_V	455_Y	1.448	0.99
291_S	411_C	1.443	0.99
77_P	118_Y	1.437	0.99
14_Y	265_L	1.436	0.99
26_Y	138_E	1.433	0.99
21_T	26_Y	1.426	0.99
395_A	407_E	1.423	0.99
346_L	365_I	1.420	0.99
179_L	232_L	1.417	0.99
68_V	75_L	1.410	0.99
172_T	224_G	1.397	0.99
367_K	370_D	1.392	0.99
214_S	334_D	1.392	0.99
115_A	119_V	1.388	0.99
451_R	458_L	1.385	0.99
290_E	415_L	1.385	0.99
115_A	178_L	1.381	0.99
450_E	454_S	1.380	0.99
59_G	233_K	1.379	0.99
40_G	88_I	1.377	0.99
343_I	354_H	1.374	0.99
222_S	226_H	1.360	0.99
33_L	137_L	1.359	0.99
22_S	268_Y	1.347	0.99
442_D	446_K	1.345	0.99
441_P	445_H	1.326	0.99
15_V	186_I	1.318	0.99
67_K	74_V	1.315	0.99
20_I	138_E	1.311	0.99
50_T	54_G	1.303	0.99
192_N	231_S	1.303	0.99
80_A	84_I	1.302	0.99
346_L	368_L	1.296	0.99
366_D	369_R	1.290	0.99
176_A	181_G	1.289	0.99
429_L	433_S	1.284	0.99
112_I	175_A	1.282	0.99
291_S	396_V	1.279	0.99
12_T	16_L	1.278	0.99
146_I	173_A	1.278	0.99
282_E	335_H	1.272	0.99
18_K	21_T	1.245	0.98
12_T	187_K	1.240	0.98
309_V	398_V	1.238	0.98
57_V	83_N	1.236	0.98
37_L	452_C	1.232	0.98
31_H	428_L	1.232	0.98
331_A	334_D	1.231	0.98
460_T	464_N	1.230	0.98
351_T	354_H	1.229	0.98
13_D	17_E	1.214	0.98
116_A	136_V	1.211	0.98
285_A	340_I	1.211	0.98
181_G	231_S	1.207	0.98
289_A	340_I	1.203	0.98
219_D	222_S	1.202	0.98
135_D	180_G	1.198	0.98
292_A	398_V	1.193	0.98
281_A	355_Y	1.193	0.98
8_I	187_K	1.189	0.98
16_L	186_I	1.188	0.98
32_V	275_F	1.187	0.98
26_Y	137_L	1.180	0.98
112_I	140_M	1.169	0.97
304_D	401_K	1.166	0.97
97_W	101_E	1.165	0.97
15_V	173_A	1.163	0.97
96_T	283_F	1.160	0.97
426_P	429_L	1.160	0.97
111_G	171_T	1.146	0.97
230_M	235_E	1.145	0.97
436_L	445_H	1.141	0.97
304_D	364_R	1.135	0.97
328_H	332_D	1.123	0.97
64_N	74_V	1.121	0.97
66_S	117_D	1.118	0.97
28_T	31_H	1.117	0.97
69_P	113_L	1.113	0.97
9_E	183_R	1.104	0.96
51_K	211_S	1.104	0.96
136_V	140_M	1.101	0.96
90_W	214_S	1.100	0.96
448_I	452_C	1.100	0.96
85_G	216_A	1.099	0.96
322_D	338_Q	1.095	0.96
295_L	398_V	1.095	0.96
340_I	355_Y	1.092	0.96
138_E	142_K	1.085	0.96
131_L	178_L	1.083	0.96
40_G	69_P	1.079	0.96
76_D	79_R	1.078	0.96
181_G	189_A	1.077	0.96
97_W	269_V	1.077	0.96
181_G	185_E	1.073	0.96
49_C	83_N	1.073	0.96
111_G	175_A	1.070	0.96
162_D	216_A	1.068	0.96
195_I	216_A	1.063	0.96
175_A	228_A	1.061	0.96
384_Y	387_P	1.058	0.95
188_N	236_M	1.057	0.95
89_R	94_N	1.055	0.95
34_L	429_L	1.054	0.95
9_E	184_E	1.053	0.95
278_S	283_F	1.047	0.95
289_A	350_I	1.044	0.95
164_V	199_A	1.044	0.95
106_S	144_H	1.044	0.95
68_V	83_N	1.038	0.95
219_D	223_R	1.038	0.95
75_L	83_N	1.034	0.95
171_T	224_G	1.022	0.95
62_V	65_G	1.015	0.94
413_F	420_R	1.009	0.94
51_K	235_E	1.008	0.94
306_I	398_V	1.008	0.94
315_E	381_T	1.008	0.94
52_L	86_C	1.007	0.94
43_A	87_M	1.005	0.94
181_G	232_L	1.001	0.94
264_P	267_A	0.999	0.94
82_F	218_G	0.994	0.94
376_E	381_T	0.994	0.94
279_Y	290_E	0.993	0.94
69_P	84_I	0.990	0.94
194_W	200_L	0.989	0.94
430_E	434_D	0.988	0.93
425_V	453_T	0.985	0.93
292_A	345_L	0.984	0.93
416_G	422_E	0.983	0.93
106_S	109_L	0.982	0.93
173_A	186_I	0.979	0.93
9_E	187_K	0.974	0.93
185_E	188_N	0.972	0.93
92_D	213_K	0.968	0.93
181_G	228_A	0.966	0.93
269_V	272_N	0.966	0.93
120_S	464_N	0.963	0.93
114_A	117_D	0.958	0.92
175_A	224_G	0.956	0.92
26_Y	141_I	0.956	0.92
35_D	431_K	0.949	0.92
188_N	231_S	0.947	0.92
61_T	64_N	0.943	0.92
380_Y	410_E	0.942	0.92
38_G	435_N	0.939	0.92
168_K	224_G	0.935	0.91
120_S	131_L	0.934	0.91
274_L	283_F	0.927	0.91
262_A	265_L	0.926	0.91
337_L	374_V	0.919	0.91
299_V	406_T	0.915	0.91
195_I	212_R	0.914	0.91
200_L	252_V	0.913	0.90
275_F	428_L	0.912	0.90
27_T	31_H	0.912	0.90
324_K	338_Q	0.907	0.90
79_R	83_N	0.905	0.90
169_V	194_W	0.901	0.90
82_F	85_G	0.901	0.90
177_K	186_I	0.898	0.90
156_L	160_G	0.886	0.89
18_K	137_L	0.883	0.89
81_A	114_A	0.881	0.89
311_I	372_M	0.877	0.89
86_C	218_G	0.877	0.89
441_P	444_Q	0.875	0.88
188_N	237_G	0.874	0.88
118_Y	229_L	0.873	0.88
131_L	136_V	0.871	0.88
211_S	235_E	0.871	0.88
283_F	286_Q	0.870	0.88
306_I	345_L	0.863	0.88
173_A	176_A	0.862	0.88
278_S	423_E	0.857	0.87
9_E	239_P	0.849	0.87
89_R	216_A	0.847	0.87
280_P	350_I	0.847	0.87
119_V	232_L	0.844	0.87
377_N	380_Y	0.844	0.87
379_T	382_E	0.842	0.87
440_F	445_H	0.840	0.86
449_Y	452_C	0.837	0.86
289_A	292_A	0.837	0.86
450_E	453_T	0.836	0.86
89_R	334_D	0.833	0.86
66_S	84_I	0.831	0.86
280_P	354_H	0.830	0.86
327_L	335_H	0.830	0.86
101_E	151_A	0.829	0.86
159_V	255_N	0.827	0.86
339_Y	343_I	0.826	0.85
120_S	460_T	0.824	0.85
229_L	233_K	0.820	0.85
149_V	264_P	0.820	0.85
342_A	368_L	0.818	0.85
51_K	54_G	0.818	0.85
77_P	114_A	0.816	0.85
81_A	111_G	0.812	0.84
15_V	177_K	0.810	0.84
311_I	396_V	0.807	0.84
78_V	229_L	0.803	0.84
8_I	191_S	0.802	0.84
202_T	240_T	0.801	0.84
185_E	232_L	0.801	0.84
288_A	311_I	0.801	0.84
267_A	272_N	0.799	0.84
14_Y	145_E	0.798	0.83
172_T	228_A	0.797	0.83
53_L	71_T	0.795	0.83
444_Q	447_H	0.795	0.83
9_E	13_D	0.794	0.83
142_K	177_K	0.794	0.83
84_I	117_D	0.791	0.83
84_I	114_A	0.790	0.83
311_I	337_L	0.783	0.82
342_A	372_M	0.782	0.82
43_A	90_W	0.781	0.82
183_R	187_K	0.781	0.82
98_L	283_F	0.780	0.82
300_K	348_G	0.779	0.82
436_L	440_F	0.778	0.82
89_R	162_D	0.778	0.82
288_A	341_T	0.777	0.82
305_E	402_D	0.776	0.82
299_V	398_V	0.775	0.82
288_A	337_L	0.775	0.82
284_H	384_Y	0.773	0.81
26_Y	134_R	0.769	0.81
96_T	392_I	0.765	0.81
36_T	109_L	0.760	0.80
292_A	299_V	0.759	0.80
343_I	365_I	0.759	0.80
15_V	176_A	0.759	0.80
284_H	314_H	0.756	0.80
198_A	253_L	0.754	0.80
296_H	345_L	0.753	0.80
94_N	213_K	0.752	0.80
17_E	183_R	0.750	0.79
168_K	197_N	0.749	0.79
213_K	216_A	0.746	0.79
459_Q	465_E	0.745	0.79
303_I	346_L	0.745	0.79
15_V	190_L	0.744	0.79
296_H	344_G	0.743	0.79
211_S	236_M	0.743	0.79
85_G	218_G	0.743	0.79
347_F	364_R	0.742	0.79
111_G	174_V	0.740	0.79
345_L	368_L	0.740	0.79
347_F	365_I	0.740	0.79
307_D	371_K	0.738	0.78
315_E	319_R	0.735	0.78
346_L	364_R	0.735	0.78
18_K	138_E	0.731	0.78
108_N	143_A	0.731	0.78
364_R	367_K	0.731	0.78
92_D	335_H	0.730	0.78
75_L	79_R	0.729	0.78
162_D	213_K	0.729	0.78
97_W	151_A	0.728	0.77
195_I	200_L	0.728	0.77
279_Y	415_L	0.727	0.77
29_A	140_M	0.725	0.77
447_H	451_R	0.724	0.77
61_T	76_D	0.723	0.77
33_L	109_L	0.721	0.77
237_G	334_D	0.721	0.77
455_Y	459_Q	0.719	0.77
27_T	453_T	0.719	0.77
223_R	227_L	0.719	0.77
58_P	73_Y	0.716	0.76
42_L	91_L	0.715	0.76
289_A	293_V	0.714	0.76
89_R	167_V	0.714	0.76
119_V	178_L	0.714	0.76
23_A	27_T	0.711	0.76
333_R	360_A	0.710	0.76
343_I	347_F	0.709	0.76
95_D	106_S	0.704	0.75
314_H	317_A	0.702	0.75
350_I	355_Y	0.699	0.75
323_K	332_D	0.699	0.75
152_L	269_V	0.699	0.75
445_H	448_I	0.699	0.75
292_A	296_H	0.698	0.74
136_V	463_V	0.697	0.74
415_L	421_R	0.697	0.74
212_R	216_A	0.692	0.74
229_L	232_L	0.692	0.74
78_V	222_S	0.692	0.74
344_G	350_I	0.690	0.74
116_A	119_V	0.690	0.74
65_G	118_Y	0.689	0.73
156_L	166_F	0.688	0.73
309_V	368_L	0.684	0.73
204_R	335_H	0.684	0.73
280_P	435_N	0.682	0.73
48_E	90_W	0.682	0.73
341_T	345_L	0.680	0.72
325_G	370_D	0.680	0.72
443_K	447_H	0.680	0.72
436_L	439_H	0.677	0.72
433_S	437_K	0.676	0.72
27_T	30_G	0.676	0.72
38_G	41_I	0.671	0.71
181_G	186_I	0.670	0.71
313_T	374_V	0.669	0.71
91_L	282_E	0.668	0.71
24_E	27_T	0.665	0.71
53_L	83_N	0.662	0.70
359_T	362_D	0.661	0.70
427_K	430_E	0.661	0.70
238_Y	245_P	0.659	0.70
45_R	50_T	0.659	0.70
296_H	299_V	0.657	0.70
7_V	243_S	0.657	0.70
371_K	401_K	0.656	0.70
112_I	143_A	0.656	0.70
97_W	196_D	0.656	0.70
417_H	420_R	0.656	0.70
112_I	169_V	0.655	0.70
89_R	217_A	0.655	0.70
460_T	465_E	0.654	0.70
89_R	107_D	0.653	0.69
33_L	136_V	0.653	0.69
133_V	136_V	0.652	0.69
162_D	195_I	0.652	0.69
36_T	40_G	0.652	0.69
288_A	394_N	0.649	0.69
157_N	204_R	0.647	0.69
303_I	400_F	0.646	0.69
29_A	270_M	0.646	0.69
149_V	262_A	0.645	0.68
257_K	260_K	0.644	0.68
433_S	442_D	0.643	0.68
82_F	222_S	0.642	0.68
42_L	352_A	0.642	0.68
307_D	310_V	0.641	0.68
284_H	317_A	0.639	0.68
67_K	84_I	0.638	0.68
52_L	56_I	0.637	0.68
459_Q	464_N	0.636	0.67
167_V	199_A	0.635	0.67
131_L	135_D	0.634	0.67
28_T	32_V	0.633	0.67
105_P	148_G	0.633	0.67
210_G	214_S	0.632	0.67
246_G	251_D	0.632	0.67
349_D	430_E	0.631	0.67
318_I	374_V	0.630	0.67
299_V	400_F	0.629	0.67
292_A	344_G	0.628	0.66
383_D	391_S	0.627	0.66
12_T	186_I	0.626	0.66
7_V	259_I	0.625	0.66
283_F	414_P	0.625	0.66
46_Y	49_C	0.624	0.66
65_G	77_P	0.624	0.66
391_S	413_F	0.623	0.66
283_F	417_H	0.621	0.66
445_H	449_Y	0.620	0.65
93_Y	280_P	0.619	0.65
164_V	167_V	0.618	0.65
330_P	360_A	0.617	0.65
112_I	171_T	0.617	0.65
108_N	112_I	0.617	0.65
150_L	262_A	0.616	0.65
96_T	103_G	0.616	0.65
451_R	454_S	0.616	0.65
361_N	366_D	0.616	0.65
282_E	321_I	0.614	0.65
167_V	220_A	0.613	0.65
133_V	460_T	0.612	0.64
218_G	221_T	0.611	0.64
33_L	455_Y	0.611	0.64
173_A	189_A	0.611	0.64
315_E	376_E	0.610	0.64
141_I	270_M	0.609	0.64
134_R	446_K	0.608	0.64
180_G	183_R	0.608	0.64
242_L	250_Q	0.607	0.64
145_E	149_V	0.607	0.64
34_L	453_T	0.607	0.64
213_K	334_D	0.605	0.64
31_H	453_T	0.605	0.64
93_Y	435_N	0.604	0.63
363_P	378_K	0.603	0.63
12_T	183_R	0.603	0.63
161_L	253_L	0.601	0.63
134_R	459_Q	0.601	0.63
20_I	26_Y	0.601	0.63
164_V	213_K	0.600	0.63
295_L	299_V	0.600	0.63
92_D	104_H	0.600	0.63
407_E	410_E	0.599	0.63
39_C	93_Y	0.597	0.63
435_N	438_T	0.596	0.62
66_S	77_P	0.595	0.62
284_H	320_I	0.594	0.62
440_F	444_Q	0.594	0.62
204_R	214_S	0.593	0.62
446_K	449_Y	0.592	0.62
21_T	138_E	0.592	0.62
305_E	404_T	0.591	0.62
161_L	200_L	0.589	0.62
25_A	28_T	0.588	0.61
97_W	103_G	0.588	0.61
52_L	83_N	0.588	0.61
170_A	174_V	0.588	0.61
292_A	396_V	0.587	0.61
116_A	463_V	0.587	0.61
8_I	242_L	0.587	0.61
57_V	60_T	0.586	0.61
296_H	303_I	0.586	0.61
250_Q	259_I	0.585	0.61
89_R	213_K	0.585	0.61
56_I	60_T	0.585	0.61
115_A	118_Y	0.585	0.61
10_E	13_D	0.584	0.61
108_N	174_V	0.583	0.61
18_K	141_I	0.581	0.60
263_R	398_V	0.580	0.60
290_E	294_I	0.580	0.60
196_D	227_L	0.579	0.60
458_L	465_E	0.579	0.60
369_R	372_M	0.579	0.60
201_R	204_R	0.578	0.60
36_T	110_G	0.578	0.60
32_V	109_L	0.577	0.60
278_S	290_E	0.576	0.60
378_K	382_E	0.575	0.60
16_L	142_K	0.575	0.60
300_K	404_T	0.575	0.60
145_E	268_Y	0.574	0.60
306_I	309_V	0.574	0.60
209_T	214_S	0.574	0.60
36_T	106_S	0.573	0.59
367_K	372_M	0.572	0.59
294_I	298_Q	0.571	0.59
199_A	216_A	0.569	0.59
298_Q	406_T	0.569	0.59
105_P	273_V	0.568	0.59
454_S	458_L	0.568	0.59
160_G	213_K	0.567	0.59
95_D	213_K	0.566	0.58
411_C	421_R	0.565	0.58
22_S	271_E	0.565	0.58
20_I	177_K	0.565	0.58
150_L	242_L	0.565	0.58
36_T	275_F	0.563	0.58
24_E	418_R	0.563	0.58
182_G	186_I	0.563	0.58
157_N	164_V	0.563	0.58
331_A	335_H	0.563	0.58
154_N	166_F	0.561	0.58
165_L	198_A	0.561	0.58
111_G	115_A	0.561	0.58
168_K	193_A	0.561	0.58
415_L	424_A	0.558	0.57
157_N	160_G	0.558	0.57
47_P	51_K	0.558	0.57
36_T	39_C	0.557	0.57
287_T	394_N	0.557	0.57
49_C	90_W	0.556	0.57
39_C	92_D	0.556	0.57
94_N	199_A	0.555	0.57
97_W	148_G	0.554	0.57
89_R	166_F	0.554	0.57
456_E	465_E	0.554	0.57
15_V	146_I	0.553	0.57
330_P	357_A	0.553	0.57
144_H	270_M	0.552	0.57
191_S	195_I	0.552	0.57
373_E	399_H	0.550	0.56
89_R	199_A	0.550	0.56
400_F	403_G	0.549	0.56
115_A	229_L	0.549	0.56
188_N	239_P	0.548	0.56
302_R	400_F	0.548	0.56
88_I	109_L	0.547	0.56
144_H	273_V	0.547	0.56
353_Q	438_T	0.544	0.56
159_V	254_F	0.544	0.56
192_N	227_L	0.541	0.55
97_W	102_W	0.540	0.55
202_T	247_W	0.540	0.55
324_K	374_V	0.539	0.55
432_F	448_I	0.539	0.55
134_R	456_E	0.538	0.55
282_E	417_H	0.537	0.55
447_H	450_E	0.536	0.54
169_V	172_T	0.536	0.54
31_H	424_A	0.536	0.54
309_V	372_M	0.535	0.54
458_L	463_V	0.534	0.54
30_G	452_C	0.533	0.54
35_D	213_K	0.533	0.54
19_E	22_S	0.533	0.54
339_Y	356_E	0.532	0.54
98_L	282_E	0.530	0.54
151_A	201_R	0.529	0.53
213_K	431_K	0.529	0.53
343_I	350_I	0.529	0.53
401_K	433_S	0.528	0.53
142_K	173_A	0.528	0.53
330_P	334_D	0.528	0.53
32_V	273_V	0.527	0.53
156_L	163_H	0.527	0.53
345_L	400_F	0.524	0.53
163_H	284_H	0.523	0.53
11_I	190_L	0.522	0.53
152_L	272_N	0.522	0.53
132_T	459_Q	0.521	0.52
216_A	334_D	0.520	0.52
298_Q	447_H	0.519	0.52
7_V	11_I	0.519	0.52
306_I	400_F	0.517	0.52
280_P	351_T	0.517	0.52
47_P	50_T	0.515	0.52
134_R	138_E	0.515	0.52
357_A	360_A	0.515	0.52
57_V	459_Q	0.514	0.51
285_A	317_A	0.514	0.51
350_I	354_H	0.514	0.51
303_I	406_T	0.513	0.51
309_V	341_T	0.512	0.51
202_T	205_H	0.512	0.51
169_V	193_A	0.511	0.51
304_D	404_T	0.510	0.51
83_N	114_A	0.509	0.51
60_T	78_V	0.507	0.50
187_K	239_P	0.507	0.50
7_V	242_L	0.507	0.50
321_I	335_H	0.507	0.50
116_A	131_L	0.507	0.50
296_H	301_N	0.507	0.50
89_R	335_H	0.506	0.50
17_E	142_K	0.506	0.50
196_D	219_D	0.506	0.50
425_V	429_L	0.506	0.50
32_V	270_M	0.506	0.50
290_E	423_E	0.505	0.50
437_K	441_P	0.505	0.50
157_N	331_A	0.504	0.50
303_I	306_I	0.503	0.50
341_T	396_V	0.503	0.50
60_T	64_N	0.502	0.50
169_V	198_A	0.500	0.49
451_R	463_V	0.500	0.49

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1szqA	2	0.9894	100	0.112	Contact Map
2hp0A	2	0.9216	100	0.114	Contact Map
4rqoA	2	0.5318	97.2	0.937	Contact Map
4rgiA	1	0.1504	20.8	0.975	Contact Map
4bhxA	2	0.1102	18.4	0.976	Contact Map
4giuA	2	0.1017	16.9	0.976	Contact Map
1ti6A	3	0.1907	15.9	0.976	Contact Map
4e6sA	2	0.1102	13.1	0.977	Contact Map
1h0hA	1	0.2013	12.9	0.977	Contact Map
1bh9B	1	0.0996	12.3	0.977	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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