GREMLIN Database
YPJH - Uncharacterized glycosyltransferase YpjH
UniProt: P42982 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 377 (346)
Sequences: 56798 (48485)
Seq/√Len: 2606.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
203_I273_S4.6571.00
231_K258_L3.7371.00
241_K245_C3.3641.00
147_R170_E3.2771.00
276_K292_A3.1081.00
201_V233_L2.9801.00
92_H370_Y2.8891.00
352_M356_E2.7681.00
223_N329_T2.7431.00
219_R247_L2.7351.00
199_E231_K2.7151.00
233_L260_L2.6881.00
227_K333_M2.6561.00
204_H214_V2.6181.00
225_A256_Q2.4001.00
156_A160_Y2.2871.00
219_R325_V2.2271.00
36_H88_L2.2091.00
213_R216_D2.1841.00
200_K336_L2.1711.00
247_L251_Y2.1211.00
223_N326_T2.0761.00
303_N308_P2.0701.00
350_I354_E2.0701.00
36_H86_E2.0621.00
338_D341_L2.0391.00
201_V231_K2.0331.00
235_V269_L2.0021.00
331_R334_S1.9981.00
221_F232_L1.9681.00
233_L258_L1.9641.00
33_H367_E1.9511.00
311_I317_G1.9481.00
201_V272_I1.9241.00
200_K274_D1.9231.00
240_E243_T1.9221.00
202_V275_L1.9141.00
334_S341_L1.8871.00
316_S352_M1.8551.00
361_K365_Q1.8431.00
296_G350_I1.8431.00
312_K315_V1.8011.00
222_R251_Y1.8001.00
342_S346_T1.7961.00
303_N321_D1.7881.00
153_S156_A1.7851.00
318_F331_R1.7841.00
92_H119_T1.7791.00
321_D327_A1.7791.00
334_S338_D1.7501.00
31_K364_S1.7431.00
147_R369_I1.7201.00
217_V232_L1.7061.00
36_H56_H1.7041.00
333_M337_E1.6991.00
175_F359_S1.6981.00
213_R281_E1.6871.00
276_K297_V1.6861.00
150_A169_I1.6791.00
156_A171_T1.6791.00
249_R254_E1.6631.00
153_S309_E1.6341.00
312_K352_M1.6321.00
221_F230_A1.6281.00
205_V266_V1.6261.00
118_T145_S1.6221.00
341_L344_R1.5821.00
217_V277_L1.5781.00
367_E371_A1.5341.00
327_A331_R1.5281.00
156_A169_I1.5251.00
324_D327_A1.5041.00
318_F334_S1.4991.00
315_V348_A1.4981.00
27_Q30_E1.4971.00
27_Q360_K1.4921.00
344_R348_A1.4901.00
153_S171_T1.4731.00
265_R268_D1.4721.00
224_I333_M1.4661.00
263_Q266_V1.4601.00
235_V260_L1.4521.00
27_Q363_V1.4451.00
237_D241_K1.4431.00
31_K367_E1.4211.00
211_V282_K1.4191.00
312_K316_S1.4091.00
22_T26_K1.4091.00
216_D325_V1.4031.00
201_V274_D1.3991.00
301_G307_I1.3951.00
215_Q247_L1.3931.00
273_S297_V1.3871.00
233_L269_L1.3761.00
246_E250_K1.3551.00
325_V329_T1.3521.00
233_L273_S1.3501.00
150_A156_A1.3291.00
320_V331_R1.3291.00
149_T369_I1.3221.00
208_F234_L1.3221.00
267_E295_C1.3091.00
223_N325_V1.3071.00
204_H217_V1.3061.00
160_Y166_E1.3051.00
220_V328_A1.2921.00
202_V277_L1.2921.00
202_V332_A1.2861.00
214_V234_L1.2821.00
348_A351_E1.2781.00
327_A330_A1.2681.00
153_S157_A1.2581.00
36_H54_H1.2541.00
149_T366_Y1.2531.00
361_K364_S1.2511.00
365_Q368_Q1.2491.00
203_I235_V1.2441.00
247_L250_K1.2241.00
93_A116_I1.2141.00
165_P168_K1.2121.00
216_D281_E1.2041.00
343_N347_K1.1951.00
242_S245_C1.1941.00
200_K275_L1.1911.00
157_A160_Y1.1851.00
285_F290_L1.1821.00
271_S295_C1.1651.00
181_Y295_C1.1581.00
329_T333_M1.1481.00
245_C249_R1.1471.00
266_V270_Y1.1291.00
278_L289_L1.1271.00
289_L307_I1.1261.00
242_S246_E1.1211.00
346_T349_A1.1181.00
215_Q219_R1.1141.00
223_N227_K1.1091.00
270_Y295_C1.1081.00
358_S361_K1.1061.00
201_V273_S1.1051.00
222_R226_G1.1041.00
339_E342_S1.1011.00
20_I287_L1.0981.00
297_V346_T1.0971.00
180_V267_E1.0951.00
296_G347_K1.0951.00
200_K230_A1.0851.00
216_D323_G1.0851.00
359_S362_I1.0841.00
151_V155_L1.0821.00
27_Q31_K1.0811.00
216_D219_R1.0771.00
279_L328_A1.0641.00
302_T320_V1.0611.00
313_N331_R1.0611.00
216_D302_T1.0601.00
362_I365_Q1.0571.00
320_V328_A1.0571.00
301_G319_L1.0551.00
351_E354_E1.0531.00
150_A159_T1.0501.00
341_L345_F1.0441.00
347_K351_E1.0431.00
335_I345_F1.0381.00
278_L288_V1.0341.00
281_E323_G1.0321.00
29_A32_G1.0301.00
151_V174_N1.0271.00
203_I269_L1.0261.00
330_A334_S1.0241.00
121_H287_L1.0161.00
267_E271_S1.0121.00
219_R251_Y1.0121.00
196_L199_E1.0101.00
318_F345_F1.0081.00
223_N226_G1.0081.00
224_I230_A1.0051.00
207_N211_V1.0051.00
364_S368_Q1.0041.00
276_K288_V1.0021.00
289_L301_G0.9921.00
260_L269_L0.9901.00
157_A161_D0.9901.00
202_V221_F0.9891.00
215_Q243_T0.9861.00
293_M299_C0.9851.00
233_L272_I0.9761.00
318_F335_I0.9721.00
150_A155_L0.9701.00
23_E26_K0.9671.00
286_G307_I0.9671.00
306_G309_E0.9631.00
200_K229_K0.9631.00
15_G18_G0.9621.00
205_V235_V0.9621.00
199_E229_K0.9621.00
339_E343_N0.9591.00
205_V270_Y0.9571.00
248_I253_L0.9551.00
116_I145_S0.9511.00
181_Y267_E0.9501.00
218_I248_I0.9441.00
174_N287_L0.9431.00
362_I366_Y0.9421.00
224_I332_A0.9421.00
263_Q267_E0.9411.00
346_T350_I0.9371.00
248_I259_M0.9341.00
293_M349_A0.9341.00
25_G37_F0.9271.00
94_H121_H0.9241.00
301_G311_I0.9241.00
170_E369_I0.9241.00
283_E286_G0.9161.00
151_V284_S0.9141.00
23_E359_S0.9131.00
217_V279_L0.9131.00
204_H234_L0.9081.00
93_A118_T0.9071.00
343_N346_T0.9051.00
175_F362_I0.9041.00
316_S349_A0.9031.00
158_E161_D0.9031.00
77_S81_E0.9021.00
145_S148_V0.8991.00
300_I320_V0.8941.00
330_A333_M0.8931.00
221_F256_Q0.8921.00
305_G308_P0.8911.00
289_L299_C0.8891.00
209_R239_P0.8871.00
345_F348_A0.8851.00
224_I336_L0.8811.00
292_A297_V0.8811.00
243_T246_E0.8801.00
216_D328_A0.8771.00
231_K256_Q0.8761.00
117_V149_T0.8741.00
103_A107_K0.8701.00
326_T330_A0.8661.00
318_F341_L0.8641.00
230_A336_L0.8631.00
178_E358_S0.8621.00
212_K283_E0.8601.00
80_A84_E0.8591.00
25_G29_A0.8521.00
224_I329_T0.8511.00
298_P346_T0.8511.00
293_M352_M0.8501.00
177_D180_V0.8481.00
246_E249_R0.8471.00
19_I23_E0.8441.00
321_D324_D0.8441.00
222_R225_A0.8411.00
275_L335_I0.8401.00
20_I121_H0.8391.00
212_K288_V0.8361.00
220_V329_T0.8361.00
204_H279_L0.8351.00
170_E365_Q0.8341.00
215_Q281_E0.8331.00
311_I319_L0.8311.00
300_I331_R0.8271.00
243_T247_L0.8251.00
364_S367_E0.8241.00
289_L310_V0.8231.00
293_M316_S0.8201.00
277_L332_A0.8201.00
154_A157_A0.8151.00
268_D272_I0.8101.00
21_A94_H0.8101.00
278_L307_I0.8091.00
269_L272_I0.8081.00
158_E162_L0.8061.00
227_K330_A0.8021.00
268_D271_S0.7971.00
136_D139_R0.7961.00
358_S362_I0.7961.00
270_Y297_V0.7961.00
219_R222_R0.7951.00
149_T172_I0.7941.00
117_V147_R0.7931.00
20_I119_T0.7921.00
219_R223_N0.7911.00
172_I369_I0.7901.00
203_I270_Y0.7891.00
220_V325_V0.7881.00
275_L332_A0.7851.00
280_S283_E0.7841.00
298_P335_I0.7841.00
215_Q240_E0.7831.00
225_A228_T0.7771.00
197_P200_K0.7771.00
352_M357_F0.7761.00
173_Y309_E0.7741.00
160_Y169_I0.7731.00
23_E27_Q0.7721.00
303_N319_L0.7651.00
227_K329_T0.7621.00
140_F144_S0.7611.00
115_G146_D0.7591.00
173_Y365_Q0.7591.00
304_I307_I0.7501.00
222_R253_L0.7481.00
210_K215_Q0.7481.00
73_L77_S0.7471.00
359_S363_V0.7471.00
208_F241_K0.7461.00
345_F349_A0.7431.00
82_V86_E0.7431.00
31_K360_K0.7421.00
313_N316_S0.7421.00
248_I257_V0.7391.00
204_H232_L0.7341.00
23_E177_D0.7331.00
248_I251_Y0.7321.00
360_K364_S0.7321.00
204_H276_K0.7291.00
112_R115_G0.7271.00
29_A35_I0.7231.00
350_I353_L0.7221.00
121_H151_V0.7211.00
344_R347_K0.7201.00
274_D342_S0.7181.00
34_E54_H0.7181.00
151_V287_L0.7151.00
76_A80_A0.7131.00
154_A158_E0.7111.00
206_S214_V0.7101.00
172_I366_Y0.7101.00
300_I335_I0.7071.00
368_Q371_A0.7071.00
90_I370_Y0.7071.00
15_G207_N0.7061.00
366_Y370_Y0.7051.00
227_K337_E0.7041.00
92_H366_Y0.7021.00
122_G211_V0.7011.00
81_E85_R0.6991.00
340_Q344_R0.6991.00
173_Y357_F0.6971.00
225_A229_K0.6971.00
286_G289_L0.6971.00
20_I366_Y0.6971.00
224_I228_T0.6951.00
160_Y163_I0.6931.00
334_S337_E0.6921.00
205_V276_K0.6911.00
20_I174_N0.6901.00
245_C259_M0.6891.00
74_T78_K0.6891.00
263_Q269_L0.6881.00
36_H40_S0.6861.00
93_A99_H0.6831.00
285_F357_F0.6811.00
19_I22_T0.6811.00
278_L286_G0.6801.00
202_V230_A0.6791.00
77_S80_A0.6791.00
302_T328_A0.6771.00
200_K339_E0.6751.00
136_D140_F0.6741.00
210_K281_E0.6741.00
326_T329_T0.6681.00
290_L357_F0.6671.00
31_K363_V0.6591.00
308_P319_L0.6581.00
184_K271_S0.6541.00
335_I342_S0.6511.00
24_L366_Y0.6501.00
206_S212_K0.6491.00
316_S348_A0.6481.00
293_M346_T0.6471.00
117_V370_Y0.6461.00
172_I365_Q0.6451.00
29_A33_H0.6451.00
340_Q343_N0.6431.00
349_A352_M0.6421.00
311_I316_S0.6391.00
177_D181_Y0.6391.00
57_E60_V0.6381.00
25_G35_I0.6351.00
302_T322_V0.6271.00
102_C105_L0.6271.00
7_G17_S0.6271.00
170_E173_Y0.6261.00
56_H60_V0.6251.00
196_L231_K0.6251.00
269_L273_S0.6251.00
202_V336_L0.6231.00
210_K240_E0.6221.00
30_E360_K0.6201.00
94_H119_T0.6191.00
338_D342_S0.6171.00
221_F224_I0.6171.00
178_E354_E0.6151.00
7_G21_A0.6141.00
314_N334_S0.6111.00
276_K299_C0.6111.00
208_F214_V0.6111.00
313_N318_F0.6101.00
104_Y107_K0.6101.00
90_I117_V0.6081.00
88_L114_I0.6081.00
320_V327_A0.6081.00
212_K280_S0.6081.00
213_R279_L0.6071.00
277_L328_A0.6071.00
52_N55_F0.6041.00
82_V85_R0.6031.00
71_Y75_L0.6031.00
220_V332_A0.6021.00
154_A308_P0.6011.00
83_A88_L0.5981.00
150_A171_T0.5981.00
228_T337_E0.5981.00
26_K51_P0.5971.00
19_I263_Q0.5921.00
240_E244_A0.5921.00
218_I257_V0.5901.00
201_V269_L0.5891.00
363_V367_E0.5891.00
26_K30_E0.5881.00
32_G367_E0.5871.00
213_R323_G0.5861.00
238_G241_K0.5851.00
203_I276_K0.5851.00
200_K342_S0.5841.00
119_T366_Y0.5831.00
195_I233_L0.5821.00
279_L302_T0.5811.00
347_K350_I0.5811.00
275_L300_I0.5801.00
300_I332_A0.5791.00
288_V292_A0.5761.00
179_R182_L0.5751.00
348_A352_M0.5741.00
56_H59_E0.5721.00
218_I244_A0.5701.00
156_A166_E0.5691.00
91_I114_I0.5681.00
266_V269_L0.5671.00
178_E294_A0.5661.00
139_R143_E0.5661.00
95_Y98_P0.5651.00
200_K203_I0.5641.00
182_L271_S0.5631.00
33_H371_A0.5631.00
29_A52_N0.5611.00
121_H174_N0.5611.00
152_S155_L0.5601.00
270_Y288_V0.5601.00
155_L158_E0.5601.00
49_Y52_N0.5601.00
274_D339_E0.5591.00
88_L91_I0.5581.00
93_A103_A0.5571.00
217_V221_F0.5571.00
245_C248_I0.5561.00
164_K167_K0.5551.00
132_P135_K0.5551.00
214_V240_E0.5531.00
292_A299_C0.5531.00
248_I254_E0.5521.00
72_D75_L0.5521.00
215_Q244_A0.5521.00
68_Y71_Y0.5511.00
216_D220_V0.5501.00
286_G290_L0.5501.00
293_M353_L0.5501.00
17_S95_Y0.5481.00
244_A247_L0.5471.00
225_A230_A0.5471.00
290_L353_L0.5451.00
116_I146_D0.5441.00
124_D127_V0.5421.00
236_G261_G0.5421.00
74_T77_S0.5411.00
342_S345_F0.5411.00
78_K81_E0.5411.00
132_P136_D0.5411.00
153_S173_Y0.5391.00
20_I24_L0.5371.00
119_T149_T0.5371.00
228_T333_M0.5371.00
235_V266_V0.5361.00
203_I297_V0.5361.00
32_G35_I0.5351.00
304_I308_P0.5341.00
356_E361_K0.5331.00
23_E287_L0.5331.00
48_T52_N0.5301.00
27_Q359_S0.5301.00
220_V224_I0.5301.00
103_A106_A0.5271.00
213_R302_T0.5271.00
210_K243_T0.5271.00
298_P342_S0.5271.00
203_I233_L0.5271.00
232_L257_V0.5241.00
290_L310_V0.5231.00
20_I94_H0.5211.00
296_G346_T0.5201.00
280_S284_S0.5191.00
303_N322_V0.5181.00
23_E175_F0.5161.00
51_P54_H0.5151.00
229_K256_Q0.5121.00
38_I82_V0.5111.00
173_Y285_F0.5101.00
25_G53_I0.5101.00
195_I201_V0.5081.00
120_L123_T0.5081.00
235_V273_S0.5071.00
147_R151_V0.5061.00
199_E272_I0.5061.00
270_Y276_K0.5021.00
263_Q268_D0.5001.00
155_L284_S0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2jjmA 4 0.9523 100 0.113 Contact Map
1rzuA 1 0.9788 100 0.151 Contact Map
2r60A 1 0.9894 100 0.153 Contact Map
3c48A 2 0.9708 100 0.155 Contact Map
4n9wA 1 0.9178 100 0.16 Contact Map
3froA 3 0.9788 100 0.163 Contact Map
2qzsA 1 0.9708 100 0.165 Contact Map
3okpA 1 0.9549 100 0.174 Contact Map
2iw1A 1 0.9496 100 0.18 Contact Map
2x6qA 1 0.9363 100 0.191 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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