DHNA - BACSU - GREMLIN Contacts

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DHNA - NADH dehydrogenase

UniProt:	P42974	Sequences: MVLDANIKAQLNQYMQLIENDIVLKVSAGEDDTSKDMLALVDELASMSSKISVEKAELNRTPSFSVNRVGEDTGVTFAGIPLGHEFTSLVLALLQVSGRPPKVDQKVIDQVKKISGEYHFESYISLTCHNCPDVVQALNMMSVLNPNITHTMIDGAAYKAEVESKNIMAVPTVYLNGESFGSGRMTLEEILAKMGSGTDASEFADKEPFDVLVVGGGPAGASAAIYTARKGIRTGVVAERFGGQVLDTMSIENFISVKATEGPKLAASLEEHVKEYDIDVMNLQRAKRLEKKDLFELELENGAVLKSKTVILSTGARWRNVNVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGIEAAIDLAGIVNHVTVLEFAPELKADEVLQKRLYSLPNVTVVKNAQTKEITGDQSVNGITYVDRETGEEKHVELQGVFVQIGLVPNTEWLEGTVERNRMGEIIVDKHGATSVPGLFAAGDCTDSAYNQIIISMGSGATAALGAFDYLIRN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	509 (505)
Sequences:	1038 (592)
Seq/√Len:	26.3

ECOLI - AHPF
BACSU - DHNA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
454_E	462_I	6.347	1.00
494_S	497_T	5.667	1.00
360_I	375_V	5.156	1.00
117_E	147_N	4.292	1.00
105_Q	109_D	3.817	1.00
349_D	371_N	3.776	1.00
122_S	150_H	3.732	1.00
446_T	480_C	3.686	1.00
409_I	436_V	3.598	1.00
393_Y	400_V	3.492	1.00
33_T	36_D	3.313	1.00
410_T	416_N	3.260	1.00
124_I	152_M	3.229	1.00
464_D	468_A	3.160	1.00
321_V	409_I	3.124	1.00
395_L	398_V	3.035	1.00
392_L	400_V	3.033	1.00
421_V	428_E	2.996	1.00
386_E	390_K	2.984	1.00
26_V	41_V	2.903	1.00
67_N	74_G	2.887	1.00
119_H	149_T	2.830	1.00
121_E	153_I	2.787	1.00
37_M	80_I	2.697	0.99
44_L	89_L	2.687	0.99
401_V	404_A	2.575	0.99
20_N	68_R	2.562	0.99
287_K	300_E	2.549	0.99
453_V	471_V	2.499	0.99
38_L	55_K	2.489	0.99
405_Q	421_V	2.478	0.99
372_H	399_T	2.439	0.99
12_N	16_Q	2.434	0.99
28_A	38_L	2.402	0.99
403_N	424_E	2.385	0.99
360_I	392_L	2.378	0.99
39_A	43_E	2.362	0.98
45_A	53_V	2.323	0.98
392_L	398_V	2.307	0.98
409_I	415_V	2.277	0.98
181_G	185_M	2.210	0.98
21_D	50_K	2.188	0.97
250_S	259_A	2.174	0.97
23_V	54_E	2.127	0.97
351_A	433_L	2.125	0.97
25_K	54_E	2.120	0.97
24_L	66_V	2.095	0.97
450_E	455_R	2.093	0.97
419_T	430_H	2.052	0.96
259_A	275_E	2.031	0.96
172_T	179_S	2.023	0.96
321_V	436_V	2.022	0.96
410_T	430_H	2.017	0.96
483_S	494_S	2.013	0.96
13_Q	16_Q	2.008	0.96
118_Y	194_M	2.002	0.96
19_E	99_R	1.994	0.96
42_D	53_V	1.973	0.95
295_F	474_L	1.973	0.95
265_L	492_M	1.971	0.95
378_F	423_R	1.963	0.95
410_T	419_T	1.951	0.95
208_P	233_R	1.944	0.95
115_S	147_N	1.897	0.94
241_F	273_V	1.885	0.94
114_I	194_M	1.856	0.93
75_V	142_S	1.844	0.93
211_V	311_I	1.837	0.93
271_E	274_K	1.830	0.93
36_D	80_I	1.812	0.93
80_I	157_A	1.809	0.93
103_V	140_M	1.793	0.92
101_P	104_D	1.792	0.92
25_K	56_A	1.787	0.92
108_I	112_K	1.783	0.92
103_V	108_I	1.772	0.92
254_F	492_M	1.738	0.91
17_L	99_R	1.707	0.90
20_N	69_V	1.707	0.90
371_N	434_Q	1.694	0.90
471_V	474_L	1.690	0.90
66_V	75_V	1.679	0.89
41_V	64_F	1.677	0.89
106_K	202_E	1.661	0.89
54_E	57_E	1.652	0.89
349_D	372_H	1.647	0.88
288_R	298_E	1.631	0.88
421_V	426_G	1.612	0.87
465_K	482_D	1.611	0.87
324_P	408_E	1.606	0.87
321_V	353_I	1.604	0.87
159_K	163_E	1.580	0.86
320_N	327_Q	1.575	0.86
33_T	157_A	1.575	0.86
222_S	255_I	1.559	0.85
160_A	164_S	1.557	0.85
79_G	152_M	1.546	0.85
69_V	75_V	1.534	0.84
235_G	281_M	1.528	0.84
71_E	74_G	1.526	0.84
28_A	57_E	1.526	0.84
206_K	279_D	1.526	0.84
287_K	298_E	1.516	0.84
166_N	413_Q	1.516	0.84
121_E	165_K	1.501	0.83
65_S	76_T	1.497	0.83
214_V	312_L	1.494	0.83
272_H	276_Y	1.491	0.83
95_Q	139_N	1.476	0.82
18_I	24_L	1.475	0.82
416_N	430_H	1.471	0.82
27_S	61_T	1.469	0.82
31_D	34_S	1.463	0.82
9_A	12_N	1.462	0.81
107_V	191_L	1.461	0.81
32_D	35_K	1.438	0.80
376_L	431_V	1.435	0.80
24_L	67_N	1.431	0.80
154_D	157_A	1.429	0.80
389_Q	393_Y	1.426	0.80
310_V	474_L	1.421	0.80
15_M	18_I	1.417	0.79
291_K	471_V	1.413	0.79
221_A	273_V	1.411	0.79
24_L	28_A	1.408	0.79
379_A	383_K	1.408	0.79
349_D	432_E	1.379	0.77
68_R	71_E	1.375	0.77
8_K	11_L	1.374	0.77
258_K	271_E	1.369	0.77
26_V	38_L	1.366	0.77
38_L	57_E	1.360	0.76
407_K	421_V	1.355	0.76
127_T	156_A	1.341	0.75
408_E	419_T	1.336	0.75
38_L	42_D	1.335	0.75
266_A	269_L	1.331	0.75
40_L	89_L	1.331	0.75
67_N	75_V	1.327	0.75
20_N	51_I	1.326	0.75
292_K	296_E	1.324	0.74
290_E	298_E	1.323	0.74
141_M	148_I	1.321	0.74
298_E	304_V	1.319	0.74
186_T	189_E	1.297	0.73
8_K	43_E	1.294	0.73
422_D	425_T	1.293	0.73
26_V	55_K	1.287	0.72
380_P	403_N	1.282	0.72
496_A	499_A	1.279	0.72
67_N	72_D	1.278	0.72
206_K	281_M	1.276	0.72
101_P	140_M	1.266	0.71
254_F	258_K	1.248	0.70
41_V	53_V	1.245	0.70
289_L	448_W	1.242	0.70
475_F	505_Y	1.242	0.70
59_N	75_V	1.235	0.69
42_D	46_S	1.235	0.69
453_V	470_S	1.234	0.69
120_F	175_L	1.232	0.69
69_V	73_T	1.231	0.69
409_I	438_V	1.227	0.69
6_N	9_A	1.221	0.68
67_N	71_E	1.221	0.68
57_E	61_T	1.217	0.68
160_A	163_E	1.209	0.67
393_Y	402_K	1.207	0.67
67_N	70_G	1.204	0.67
68_R	73_T	1.203	0.67
67_N	73_T	1.199	0.67
68_R	72_D	1.196	0.67
123_Y	161_E	1.196	0.67
392_L	395_L	1.194	0.66
35_K	38_L	1.190	0.66
412_D	416_N	1.188	0.66
321_V	438_V	1.180	0.66
296_E	304_V	1.179	0.65
320_N	336_Y	1.177	0.65
38_L	53_V	1.173	0.65
96_V	143_V	1.171	0.65
28_A	61_T	1.168	0.65
467_G	501_G	1.167	0.65
399_T	429_K	1.164	0.64
22_I	66_V	1.161	0.64
166_N	414_S	1.152	0.64
20_N	97_S	1.138	0.63
167_I	174_Y	1.137	0.63
237_V	299_L	1.136	0.62
27_S	57_E	1.133	0.62
108_I	140_M	1.132	0.62
6_N	82_L	1.126	0.62
393_Y	399_T	1.121	0.61
286_A	474_L	1.117	0.61
22_I	68_R	1.114	0.61
489_I	492_M	1.112	0.61
209_F	235_G	1.110	0.61
6_N	436_V	1.108	0.61
314_T	480_C	1.103	0.60
32_D	36_D	1.103	0.60
286_A	448_W	1.099	0.60
213_V	492_M	1.096	0.60
282_N	313_S	1.093	0.59
320_N	331_N	1.092	0.59
246_L	266_A	1.090	0.59
126_L	132_P	1.089	0.59
286_A	289_L	1.085	0.59
66_V	152_M	1.084	0.59
28_A	56_A	1.084	0.59
317_R	447_E	1.076	0.58
43_E	46_S	1.075	0.58
399_T	402_K	1.071	0.58
153_I	165_K	1.067	0.58
95_Q	101_P	1.067	0.58
364_I	395_L	1.067	0.58
419_T	428_E	1.066	0.58
39_A	42_D	1.065	0.57
71_E	75_V	1.063	0.57
38_L	49_S	1.053	0.57
42_D	52_S	1.052	0.56
127_T	154_D	1.046	0.56
449_L	455_R	1.045	0.56
122_S	152_M	1.045	0.56
404_A	420_Y	1.041	0.56
23_V	52_S	1.041	0.56
47_M	99_R	1.040	0.56
379_A	458_M	1.037	0.55
65_S	73_T	1.036	0.55
108_I	144_L	1.035	0.55
73_T	96_V	1.034	0.55
130_N	134_V	1.033	0.55
258_K	275_E	1.032	0.55
312_L	455_R	1.027	0.55
45_A	51_I	1.021	0.54
70_G	74_G	1.020	0.54
26_V	53_V	1.019	0.54
13_Q	17_L	1.014	0.54
239_E	285_R	1.012	0.54
273_V	278_I	1.010	0.53
209_F	281_M	1.002	0.53
383_K	458_M	1.001	0.53
22_I	75_V	1.000	0.53
58_L	61_T	0.998	0.52
296_E	306_K	0.996	0.52
103_V	191_L	0.993	0.52
18_I	67_N	0.992	0.52
109_D	474_L	0.991	0.52
254_F	265_L	0.991	0.52
310_V	425_T	0.989	0.52
19_E	24_L	0.989	0.52
216_G	238_A	0.989	0.52
42_D	55_K	0.983	0.51
17_L	95_Q	0.976	0.51
73_T	143_V	0.975	0.51
12_N	18_I	0.975	0.51
12_N	49_S	0.975	0.51
24_L	51_I	0.967	0.50
463_V	494_S	0.966	0.50
5_A	32_D	0.965	0.50
95_Q	143_V	0.964	0.50
456_N	482_D	0.963	0.50
16_Q	50_K	0.960	0.50
210_D	227_T	0.956	0.49
467_G	497_T	0.956	0.49
463_V	483_S	0.954	0.49
329_F	412_D	0.953	0.49
199_D	202_E	0.953	0.49
270_E	274_K	0.952	0.49
15_M	93_L	0.952	0.49
295_F	310_V	0.950	0.49
25_K	28_A	0.950	0.49
33_T	51_I	0.943	0.48
109_D	112_K	0.941	0.48
25_K	67_N	0.939	0.48
20_N	113_K	0.939	0.48
29_G	451_G	0.936	0.48
188_E	282_N	0.936	0.48
313_S	320_N	0.934	0.48
6_N	19_E	0.931	0.48
335_A	369_I	0.931	0.48
249_M	263_P	0.930	0.47
64_F	392_L	0.927	0.47
25_K	65_S	0.926	0.47
467_G	494_S	0.925	0.47
454_E	470_S	0.924	0.47
36_D	53_V	0.922	0.47
321_V	458_M	0.917	0.46
60_R	161_E	0.916	0.46
130_N	184_R	0.911	0.46
114_I	148_I	0.911	0.46
349_D	434_Q	0.910	0.46
13_Q	33_T	0.910	0.46
53_V	56_A	0.901	0.45
468_A	505_Y	0.899	0.45
55_K	61_T	0.894	0.45
455_R	458_M	0.892	0.45
123_Y	174_Y	0.890	0.44
181_G	190_I	0.888	0.44
140_M	143_V	0.888	0.44
417_G	430_H	0.887	0.44
103_V	107_V	0.885	0.44
208_P	294_L	0.884	0.44
49_S	410_T	0.883	0.44
17_L	75_V	0.882	0.44
36_D	39_A	0.881	0.44
422_D	429_K	0.881	0.44
420_Y	429_K	0.878	0.44
101_P	144_L	0.875	0.43
291_K	295_F	0.875	0.43
452_T	480_C	0.874	0.43
15_M	44_L	0.874	0.43
28_A	58_L	0.874	0.43
15_M	82_L	0.873	0.43
207_E	233_R	0.870	0.43
327_Q	336_Y	0.867	0.43
240_R	247_D	0.867	0.43
109_D	113_K	0.866	0.43
140_M	187_L	0.863	0.43
44_L	168_M	0.859	0.42
167_I	308_K	0.857	0.42
51_I	55_K	0.857	0.42
484_A	497_T	0.856	0.42
56_A	61_T	0.847	0.41
466_H	501_G	0.847	0.41
28_A	59_N	0.842	0.41
337_C	341_D	0.841	0.41
58_L	123_Y	0.841	0.41
15_M	90_V	0.839	0.41
21_D	31_D	0.838	0.41
127_T	209_F	0.836	0.41
463_V	482_D	0.834	0.40
144_L	429_K	0.833	0.40
281_M	301_N	0.833	0.40
20_N	67_N	0.833	0.40
351_A	418_I	0.830	0.40
103_V	187_L	0.827	0.40
13_Q	54_E	0.825	0.40
51_I	93_L	0.822	0.40
451_G	474_L	0.821	0.39
462_I	465_K	0.820	0.39
461_I	476_A	0.819	0.39
456_N	460_E	0.819	0.39
24_L	68_R	0.814	0.39
409_I	416_N	0.814	0.39
55_K	59_N	0.813	0.39
105_Q	386_E	0.811	0.39
32_D	45_A	0.804	0.38
73_T	76_T	0.803	0.38
43_E	142_S	0.802	0.38
104_D	109_D	0.801	0.38
24_L	95_Q	0.797	0.38
38_L	59_N	0.797	0.38
68_R	75_V	0.796	0.38
20_N	28_A	0.795	0.38
42_D	293_D	0.793	0.38
12_N	313_S	0.792	0.37
19_E	73_T	0.791	0.37
58_L	76_T	0.791	0.37
27_S	63_S	0.790	0.37
255_I	400_V	0.790	0.37
28_A	35_K	0.788	0.37
23_V	67_N	0.786	0.37
5_A	12_N	0.786	0.37
19_E	67_N	0.783	0.37
337_C	340_C	0.783	0.37
90_V	93_L	0.778	0.36
38_L	61_T	0.778	0.36
35_K	42_D	0.777	0.36
117_E	149_T	0.776	0.36
376_L	379_A	0.775	0.36
59_N	76_T	0.773	0.36
107_V	111_V	0.773	0.36
5_A	50_K	0.773	0.36
17_L	101_P	0.772	0.36
19_E	95_Q	0.771	0.36
95_Q	99_R	0.770	0.36
404_A	407_K	0.770	0.36
19_E	74_G	0.770	0.36
292_K	295_F	0.769	0.36
359_G	377_E	0.769	0.36
236_V	277_D	0.767	0.36
456_N	496_A	0.767	0.36
75_V	96_V	0.766	0.36
28_A	54_E	0.765	0.36
35_K	54_E	0.765	0.36
66_V	124_I	0.764	0.36
101_P	191_L	0.764	0.36
9_A	42_D	0.760	0.35
22_I	67_N	0.759	0.35
25_K	57_E	0.757	0.35
24_L	73_T	0.756	0.35
42_D	45_A	0.749	0.34
210_D	308_K	0.749	0.34
79_G	124_I	0.749	0.34
43_E	82_L	0.746	0.34
28_A	55_K	0.743	0.34
56_A	76_T	0.743	0.34
9_A	69_V	0.742	0.34
267_A	270_E	0.742	0.34
65_S	71_E	0.739	0.34
295_F	471_V	0.737	0.34
311_I	477_A	0.736	0.34
39_A	58_L	0.736	0.34
17_L	46_S	0.733	0.33
66_V	69_V	0.733	0.33
100_P	114_I	0.733	0.33
75_V	143_V	0.731	0.33
25_K	61_T	0.731	0.33
183_G	190_I	0.729	0.33
377_E	423_R	0.728	0.33
24_L	45_A	0.728	0.33
37_M	157_A	0.727	0.33
320_N	436_V	0.725	0.33
75_V	239_E	0.725	0.33
214_V	228_A	0.724	0.33
18_I	73_T	0.724	0.33
348_K	353_I	0.724	0.33
375_V	378_F	0.723	0.33
18_I	103_V	0.722	0.33
124_I	154_D	0.722	0.33
19_E	101_P	0.720	0.33
320_N	330_K	0.719	0.33
199_D	301_N	0.717	0.32
21_D	29_G	0.717	0.32
35_K	427_E	0.714	0.32
129_H	249_M	0.713	0.32
410_T	417_G	0.713	0.32
6_N	72_D	0.712	0.32
54_E	72_D	0.712	0.32
281_M	313_S	0.712	0.32
4_D	87_T	0.712	0.32
469_T	476_A	0.707	0.32
38_L	76_T	0.707	0.32
7_I	292_K	0.707	0.32
17_L	51_I	0.707	0.32
360_I	379_A	0.705	0.32
206_K	209_F	0.703	0.31
294_L	306_K	0.703	0.31
456_N	471_V	0.703	0.31
214_V	297_L	0.702	0.31
394_S	398_V	0.702	0.31
9_A	26_V	0.702	0.31
389_Q	400_V	0.701	0.31
23_V	53_V	0.699	0.31
7_I	37_M	0.699	0.31
19_E	97_S	0.699	0.31
42_D	76_T	0.698	0.31
9_A	35_K	0.697	0.31
30_E	236_V	0.696	0.31
7_I	16_Q	0.695	0.31
138_L	150_H	0.694	0.31
8_K	47_M	0.693	0.31
364_I	394_S	0.693	0.31
270_E	282_N	0.691	0.31
20_N	72_D	0.691	0.31
17_L	20_N	0.690	0.31
19_E	34_S	0.689	0.31
330_K	336_Y	0.689	0.31
25_K	35_K	0.688	0.31
119_H	151_T	0.688	0.31
370_V	374_T	0.687	0.30
15_M	51_I	0.687	0.30
44_L	51_I	0.685	0.30
12_N	52_S	0.684	0.30
307_S	310_V	0.682	0.30
56_A	59_N	0.681	0.30
292_K	308_K	0.681	0.30
129_H	311_I	0.679	0.30
115_S	118_Y	0.677	0.30
277_D	294_L	0.676	0.30
32_D	61_T	0.674	0.30
75_V	294_L	0.674	0.30
381_E	386_E	0.674	0.30
322_N	489_I	0.673	0.30
174_Y	179_S	0.672	0.30
39_A	46_S	0.668	0.29
18_I	37_M	0.666	0.29
122_S	129_H	0.665	0.29
23_V	69_V	0.665	0.29
451_G	454_E	0.663	0.29
96_V	142_S	0.661	0.29
65_S	74_G	0.661	0.29
67_N	76_T	0.660	0.29
20_N	24_L	0.659	0.29
28_A	34_S	0.658	0.29
184_R	368_G	0.658	0.29
57_E	443_V	0.657	0.29
187_L	194_M	0.656	0.29
66_V	73_T	0.655	0.28
24_L	71_E	0.655	0.28
34_S	61_T	0.654	0.28
162_V	169_A	0.652	0.28
35_K	39_A	0.652	0.28
19_E	50_K	0.650	0.28
106_K	109_D	0.649	0.28
250_S	492_M	0.648	0.28
391_R	394_S	0.647	0.28
22_I	42_D	0.646	0.28
51_I	298_E	0.646	0.28
275_E	353_I	0.644	0.28
27_S	68_R	0.643	0.28
17_L	58_L	0.642	0.28
18_I	22_I	0.641	0.28
7_I	90_V	0.640	0.28
6_N	47_M	0.640	0.28
254_F	489_I	0.640	0.28
317_R	347_G	0.640	0.28
95_Q	100_P	0.639	0.28
6_N	399_T	0.638	0.27
21_D	54_E	0.637	0.27
32_D	71_E	0.637	0.27
249_M	330_K	0.635	0.27
42_D	54_E	0.633	0.27
30_E	485_Y	0.633	0.27
57_E	71_E	0.631	0.27
154_D	257_V	0.631	0.27
40_L	43_E	0.630	0.27
17_L	80_I	0.629	0.27
27_S	56_A	0.628	0.27
43_E	47_M	0.628	0.27
104_D	107_V	0.628	0.27
13_Q	35_K	0.628	0.27
307_S	311_I	0.627	0.27
53_V	69_V	0.626	0.27
375_V	392_L	0.626	0.27
20_N	42_D	0.625	0.27
163_E	166_N	0.625	0.27
65_S	70_G	0.624	0.27
5_A	46_S	0.623	0.27
225_I	313_S	0.623	0.27
36_D	72_D	0.622	0.27
26_V	44_L	0.622	0.27
310_V	452_T	0.622	0.27
11_L	40_L	0.622	0.27
227_T	499_A	0.620	0.26
30_E	42_D	0.620	0.26
391_R	491_S	0.617	0.26
259_A	499_A	0.614	0.26
351_A	376_L	0.614	0.26
237_V	286_A	0.614	0.26
27_S	59_N	0.614	0.26
56_A	483_S	0.613	0.26
26_V	375_V	0.613	0.26
25_K	31_D	0.612	0.26
22_I	51_I	0.611	0.26
236_V	273_V	0.610	0.26
123_Y	496_A	0.610	0.26
37_M	101_P	0.609	0.26
5_A	18_I	0.609	0.26
12_N	82_L	0.608	0.26
13_Q	19_E	0.607	0.26
209_F	289_L	0.607	0.26
28_A	49_S	0.607	0.26
312_L	446_T	0.606	0.26
6_N	42_D	0.606	0.26
54_E	69_V	0.605	0.26
101_P	111_V	0.605	0.26
52_S	424_E	0.602	0.25
426_G	485_Y	0.601	0.25
69_V	74_G	0.601	0.25
35_K	46_S	0.601	0.25
53_V	298_E	0.601	0.25
254_F	272_H	0.600	0.25
6_N	58_L	0.599	0.25
46_S	49_S	0.598	0.25
208_P	307_S	0.598	0.25
18_I	21_D	0.596	0.25
316_A	355_G	0.596	0.25
118_Y	175_L	0.596	0.25
181_G	189_E	0.594	0.25
362_A	385_D	0.593	0.25
58_L	71_E	0.592	0.25
55_K	69_V	0.592	0.25
274_K	282_N	0.591	0.25
15_M	78_A	0.591	0.25
401_V	420_Y	0.590	0.25
24_L	292_K	0.590	0.25
21_D	189_E	0.590	0.25
325_G	328_E	0.589	0.25
289_L	310_V	0.589	0.25
22_I	59_N	0.589	0.25
96_V	150_H	0.587	0.25
21_D	49_S	0.586	0.24
20_N	53_V	0.586	0.24
262_G	487_Q	0.586	0.24
492_M	496_A	0.585	0.24
42_D	57_E	0.584	0.24
49_S	109_D	0.584	0.24
69_V	96_V	0.583	0.24
288_R	452_T	0.583	0.24
57_E	292_K	0.582	0.24
51_I	307_S	0.582	0.24
259_A	379_A	0.581	0.24
24_L	53_V	0.581	0.24
25_K	55_K	0.581	0.24
168_M	172_T	0.581	0.24
6_N	51_I	0.580	0.24
58_L	63_S	0.580	0.24
13_Q	55_K	0.580	0.24
68_R	74_G	0.580	0.24
13_Q	47_M	0.579	0.24
216_G	382_L	0.577	0.24
36_D	66_V	0.575	0.24
5_A	9_A	0.575	0.24
343_P	493_G	0.575	0.24
59_N	63_S	0.574	0.24
362_A	365_D	0.574	0.24
89_L	370_V	0.574	0.24
9_A	13_Q	0.573	0.24
31_D	41_V	0.572	0.24
40_L	51_I	0.572	0.24
258_K	312_L	0.570	0.24
65_S	69_V	0.570	0.24
244_Q	487_Q	0.569	0.24
113_K	471_V	0.568	0.24
56_A	65_S	0.567	0.23
70_G	453_V	0.567	0.23
250_S	327_Q	0.566	0.23
322_N	419_T	0.566	0.23
205_D	301_N	0.565	0.23
43_E	383_K	0.565	0.23
55_K	58_L	0.565	0.23
35_K	69_V	0.565	0.23
322_N	485_Y	0.564	0.23
129_H	144_L	0.564	0.23
14_Y	44_L	0.564	0.23
300_E	474_L	0.563	0.23
285_R	289_L	0.562	0.23
30_E	35_K	0.562	0.23
28_A	41_V	0.562	0.23
55_K	293_D	0.562	0.23
386_E	421_V	0.561	0.23
479_D	495_G	0.560	0.23
333_G	340_C	0.560	0.23
30_E	59_N	0.558	0.23
35_K	61_T	0.558	0.23
36_D	157_A	0.554	0.23
12_N	67_N	0.554	0.23
8_K	450_E	0.554	0.23
12_N	33_T	0.554	0.23
50_K	293_D	0.553	0.23
52_S	72_D	0.552	0.23
13_Q	20_N	0.552	0.23
331_N	480_C	0.552	0.23
46_S	61_T	0.552	0.23
218_P	326_E	0.551	0.23
13_Q	56_A	0.549	0.23
386_E	447_E	0.548	0.22
375_V	389_Q	0.548	0.22
46_S	80_I	0.547	0.22
226_Y	326_E	0.547	0.22
114_I	172_T	0.546	0.22
33_T	80_I	0.545	0.22
379_A	405_Q	0.545	0.22
47_M	56_A	0.545	0.22
46_S	53_V	0.544	0.22
6_N	46_S	0.544	0.22
87_T	431_V	0.543	0.22
26_V	58_L	0.543	0.22
5_A	67_N	0.543	0.22
45_A	66_V	0.542	0.22
291_K	294_L	0.541	0.22
145_N	153_I	0.540	0.22
357_N	384_A	0.540	0.22
47_M	51_I	0.539	0.22
256_S	272_H	0.539	0.22
25_K	53_V	0.538	0.22
52_S	69_V	0.538	0.22
61_T	71_E	0.538	0.22
58_L	65_S	0.537	0.22
29_G	72_D	0.537	0.22
25_K	72_D	0.536	0.22
51_I	67_N	0.536	0.22
30_E	61_T	0.535	0.22
201_S	204_A	0.534	0.22
482_D	497_T	0.534	0.22
18_I	49_S	0.534	0.22
67_N	499_A	0.534	0.22
24_L	424_E	0.532	0.22
159_K	491_S	0.532	0.22
5_A	13_Q	0.532	0.22
153_I	156_A	0.531	0.22
16_Q	23_V	0.531	0.22
119_H	463_V	0.530	0.22
71_E	290_E	0.530	0.22
336_Y	481_T	0.529	0.21
360_I	376_L	0.529	0.21
122_S	139_N	0.528	0.21
38_L	56_A	0.528	0.21
66_V	258_K	0.526	0.21
8_K	12_N	0.526	0.21
119_H	122_S	0.524	0.21
295_F	499_A	0.524	0.21
113_K	191_L	0.523	0.21
112_K	236_V	0.523	0.21
12_N	27_S	0.522	0.21
19_E	43_E	0.522	0.21
430_H	436_V	0.522	0.21
497_T	501_G	0.521	0.21
28_A	292_K	0.521	0.21
7_I	25_K	0.520	0.21
8_K	14_Y	0.520	0.21
273_V	406_T	0.520	0.21
156_A	389_Q	0.520	0.21
5_A	54_E	0.520	0.21
237_V	301_N	0.519	0.21
447_E	450_E	0.519	0.21
8_K	32_D	0.519	0.21
463_V	501_G	0.519	0.21
156_A	169_A	0.519	0.21
31_D	58_L	0.518	0.21
20_N	54_E	0.518	0.21
101_P	107_V	0.516	0.21
230_K	460_E	0.516	0.21
226_Y	337_C	0.515	0.21
23_V	33_T	0.515	0.21
20_N	38_L	0.514	0.21
220_G	353_I	0.514	0.21
19_E	71_E	0.513	0.21
78_A	151_T	0.513	0.21
108_I	287_K	0.513	0.21
20_N	31_D	0.512	0.21
240_R	269_L	0.512	0.21
97_S	101_P	0.512	0.21
75_V	152_M	0.511	0.21
221_A	236_V	0.510	0.21
366_L	493_G	0.510	0.21
244_Q	337_C	0.509	0.20
64_F	360_I	0.509	0.20
12_N	254_F	0.509	0.20
295_F	313_S	0.509	0.20
65_S	371_N	0.508	0.20
236_V	282_N	0.508	0.20
290_E	293_D	0.508	0.20
322_N	401_V	0.508	0.20
411_G	477_A	0.508	0.20
275_E	499_A	0.507	0.20
42_D	80_I	0.507	0.20
9_A	20_N	0.506	0.20
375_V	380_P	0.506	0.20
239_E	283_L	0.506	0.20
260_T	264_K	0.506	0.20
25_K	68_R	0.506	0.20
95_Q	122_S	0.505	0.20
24_L	38_L	0.505	0.20
271_E	427_E	0.505	0.20
169_A	172_T	0.505	0.20
27_S	38_L	0.504	0.20
5_A	76_T	0.504	0.20
104_D	185_M	0.504	0.20
463_V	497_T	0.503	0.20
185_M	190_I	0.502	0.20
181_G	186_T	0.501	0.20
66_V	499_A	0.501	0.20
32_D	82_L	0.501	0.20
260_T	359_G	0.501	0.20
187_L	191_L	0.500	0.20
279_D	405_Q	0.500	0.20

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1hyuA	2	0.998	100	0.38	Contact Map
2vdcG	1	0.7701	100	0.602	Contact Map
4ylfB	1	0.8035	100	0.607	Contact Map
1gteA	4	0.8861	100	0.607	Contact Map
1fl2A	2	0.5933	100	0.625	Contact Map
2x8gA	2	0.7642	100	0.631	Contact Map
2q7vA	2	0.6012	100	0.633	Contact Map
2a87A	2	0.5992	100	0.638	Contact Map
3f8dA	2	0.6012	100	0.64	Contact Map
2q0lA	2	0.5894	100	0.642	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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