BGLA - BACSU - GREMLIN Contacts

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BGLA - Aryl-phospho-beta-D-glucosidase BglA

UniProt:	P42973	Sequences: MGNMPKDFLWGGALAAHQFEGGWNQGGKGPSVVDVMTAGAHGVPRKITDTIEENEFYPNHEAIDFYHRYKEDIALFAEMGLKCLRTSIGWSRIFPKGDEAEPNEAGLQFYDDVFDELLKHGIEPVITLSHFEMPLHLAREYGGFRNRKVVDFFVNFAEACFTRYKDKVKYWMTFNEINNQMDVNNPLFLWTNSGVVVGENENAKEVMYQTAHHELVASALAVAKGKDINPEFQIGAMVSHVPIYPFSSNPEDVMLAEEEMRQRYFFPDVQVRGYYPSYALKEFEREGYNITFEDGDDEILRNGTVDYLGFSYYMSTTVKSDVKNDNTGDIVNGGLPNGVENPYITSSDWGWAIDPTGLRYTLNRFYDRYQIPLFIVENGFGAVDTLEEDGKVHDPERIQYLKSHIEALKKAVTYDGVDLIGYTPWGIIDIVSFTTGEMKKRYGMIYVDRDNEGNGSMKRYKKDSFEWYKNVIQTNGEEL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	479 (436)
Sequences:	6744 (4176)
Seq/√Len:	200.0

ECOLI - ASCB BGLA BGLB
BACSU - BGLA BGLC BGLH GMUD
SULSO - BGAL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
26_G	105_A	4.256	1.00
393_H	463_D	4.102	1.00
115_D	167_K	3.657	1.00
408_L	419_L	3.230	1.00
111_D	167_K	3.222	1.00
77_A	120_H	3.102	1.00
70_K	116_E	3.065	1.00
111_D	163_R	2.942	1.00
128_L	160_C	2.936	1.00
116_E	119_K	2.916	1.00
461_K	465_F	2.916	1.00
64_D	67_H	2.865	1.00
104_E	108_Q	2.851	1.00
108_Q	112_D	2.794	1.00
104_E	163_R	2.792	1.00
94_F	159_A	2.765	1.00
312_Y	404_H	2.759	1.00
407_A	410_K	2.727	1.00
247_S	252_D	2.622	1.00
25_Q	67_H	2.603	1.00
158_E	162_T	2.580	1.00
12_G	81_L	2.500	1.00
401_L	424_P	2.375	1.00
359_R	415_D	2.329	1.00
74_A	120_H	2.310	1.00
363_N	415_D	2.287	1.00
38_A	60_H	2.278	1.00
147_R	296_D	2.274	1.00
399_Q	403_S	2.272	1.00
225_G	234_I	2.264	1.00
151_D	220_L	2.242	1.00
114_F	164_Y	2.186	1.00
65_F	109_F	2.179	1.00
223_A	227_D	2.170	1.00
446_Y	460_Y	2.170	1.00
70_K	112_D	2.151	1.00
395_P	463_D	2.145	1.00
83_C	423_T	2.094	1.00
123_E	169_K	2.068	1.00
73_I	113_V	2.033	1.00
88_I	126_I	2.032	1.00
469_K	473_Q	2.026	1.00
65_F	84_L	2.009	1.00
35_V	135_L	1.966	1.00
154_V	224_K	1.950	1.00
105_A	108_Q	1.942	1.00
387_E	391_K	1.936	1.00
118_L	167_K	1.921	1.00
277_S	281_K	1.893	1.00
158_E	224_K	1.867	1.00
86_T	114_F	1.866	1.00
212_H	275_Y	1.854	1.00
295_G	298_E	1.849	1.00
23_W	30_P	1.846	1.00
31_S	91_S	1.839	1.00
73_I	120_H	1.838	1.00
111_D	115_D	1.818	1.00
158_E	228_I	1.806	1.00
229_N	232_F	1.792	1.00
225_G	232_F	1.778	1.00
359_R	410_K	1.777	1.00
244_Y	360_Y	1.768	1.00
30_P	35_V	1.766	1.00
220_L	299_I	1.758	1.00
10_W	475_N	1.724	1.00
14_L	19_F	1.709	1.00
115_D	118_L	1.690	1.00
116_E	120_H	1.689	1.00
86_T	113_V	1.684	1.00
123_E	170_Y	1.656	1.00
22_G	25_Q	1.654	1.00
117_L	122_I	1.646	1.00
114_F	118_L	1.641	1.00
136_H	140_E	1.631	1.00
356_T	407_A	1.627	1.00
141_Y	152_F	1.623	1.00
292_F	297_D	1.621	1.00
470_N	473_Q	1.617	1.00
362_L	417_V	1.602	1.00
154_V	220_L	1.601	1.00
111_D	164_Y	1.593	1.00
73_I	116_E	1.582	1.00
74_A	116_E	1.581	1.00
312_Y	357_G	1.579	1.00
43_V	46_K	1.571	1.00
69_Y	112_D	1.571	1.00
364_R	368_R	1.570	1.00
359_R	363_N	1.568	1.00
272_R	370_Q	1.546	1.00
261_R	278_Y	1.545	1.00
172_M	237_M	1.534	1.00
9_L	83_C	1.532	1.00
374_F	420_I	1.532	1.00
83_C	125_V	1.530	1.00
17_H	59_N	1.523	1.00
149_V	152_F	1.520	1.00
68_R	71_E	1.502	1.00
145_R	206_V	1.499	1.00
211_A	266_F	1.498	1.00
29_G	97_G	1.495	1.00
14_L	84_L	1.476	1.00
267_P	308_L	1.474	1.00
265_F	279_A	1.466	1.00
161_F	225_G	1.459	1.00
298_E	302_N	1.455	1.00
166_D	229_N	1.445	1.00
107_L	159_A	1.439	1.00
76_F	81_L	1.425	1.00
378_N	422_Y	1.416	1.00
73_I	117_L	1.415	1.00
358_L	408_L	1.414	1.00
94_F	102_P	1.407	1.00
172_M	307_Y	1.402	1.00
409_K	413_T	1.394	1.00
86_T	126_I	1.390	1.00
78_E	465_F	1.386	1.00
142_G	146_N	1.385	1.00
424_P	444_M	1.374	1.00
224_K	227_D	1.359	1.00
35_V	140_E	1.355	1.00
125_V	423_T	1.354	1.00
170_Y	233_Q	1.352	1.00
169_K	231_E	1.340	1.00
274_Y	280_L	1.330	1.00
22_G	67_H	1.320	1.00
88_I	160_C	1.317	1.00
470_N	474_T	1.315	1.00
467_W	471_V	1.315	1.00
362_L	408_L	1.305	1.00
461_K	466_E	1.304	1.00
236_A	270_Q	1.300	1.00
64_D	68_R	1.298	1.00
274_Y	370_Q	1.280	1.00
348_D	383_V	1.272	1.00
405_I	408_L	1.259	1.00
174_F	217_A	1.253	1.00
151_D	154_V	1.248	1.00
147_R	213_H	1.237	1.00
98_D	152_F	1.234	1.00
174_F	214_E	1.230	1.00
223_A	302_N	1.228	1.00
148_K	151_D	1.226	1.00
403_S	406_E	1.223	1.00
402_K	406_E	1.219	1.00
466_E	469_K	1.207	1.00
107_L	163_R	1.207	1.00
76_F	445_I	1.206	1.00
297_D	300_L	1.204	1.00
180_Q	214_E	1.201	1.00
88_I	93_I	1.196	1.00
74_A	78_E	1.195	1.00
363_N	417_V	1.190	1.00
111_D	166_D	1.175	1.00
386_L	460_Y	1.174	1.00
98_D	141_Y	1.170	1.00
65_F	113_V	1.169	1.00
5_P	412_V	1.166	1.00
293_E	296_D	1.166	1.00
96_K	136_H	1.161	1.00
161_F	221_A	1.161	1.00
366_Y	371_I	1.160	1.00
391_K	463_D	1.152	1.00
69_Y	116_E	1.148	1.00
135_L	140_E	1.146	1.00
133_M	149_V	1.143	1.00
29_G	136_H	1.139	1.00
63_I	428_I	1.134	1.00
14_L	86_T	1.132	1.00
162_T	228_I	1.130	1.00
366_Y	418_D	1.125	1.00
154_V	221_A	1.123	1.00
268_D	368_R	1.122	1.00
449_R	457_M	1.120	1.00
144_F	149_V	1.120	1.00
23_W	28_K	1.119	1.00
250_P	254_M	1.118	1.00
128_L	153_F	1.117	1.00
245_P	256_A	1.117	1.00
157_A	221_A	1.116	1.00
191_T	194_G	1.115	1.00
387_E	393_H	1.114	1.00
107_L	111_D	1.094	1.00
161_F	234_I	1.094	1.00
225_G	229_N	1.093	1.00
260_M	364_R	1.092	1.00
114_F	126_I	1.092	1.00
409_K	412_V	1.088	1.00
268_D	272_R	1.084	1.00
222_V	226_K	1.083	1.00
245_P	253_V	1.083	1.00
240_H	361_T	1.077	1.00
114_F	167_K	1.073	1.00
22_G	26_G	1.071	1.00
148_K	152_F	1.063	1.00
78_E	461_K	1.059	1.00
138_A	185_N	1.056	1.00
141_Y	148_K	1.056	1.00
250_P	253_V	1.055	1.00
356_T	360_Y	1.054	1.00
224_K	228_I	1.053	1.00
154_V	158_E	1.053	1.00
243_I	259_E	1.052	1.00
96_K	101_E	1.042	1.00
102_P	159_A	1.034	1.00
4_M	412_V	1.033	1.00
468_Y	472_I	1.028	1.00
251_E	320_S	1.028	1.00
61_E	449_R	1.027	1.00
246_F	319_K	1.027	1.00
399_Q	402_K	1.024	1.00
111_D	118_L	1.024	1.00
249_N	253_V	1.023	1.00
29_G	95_P	1.022	1.00
213_H	216_V	1.022	1.00
225_G	230_P	1.021	1.00
254_M	258_E	1.021	1.00
223_A	303_G	1.016	1.00
358_L	419_L	1.012	1.00
448_D	458_K	1.011	1.00
390_G	460_Y	1.011	1.00
251_E	356_T	1.010	1.00
12_G	76_F	1.008	1.00
4_M	409_K	1.008	1.00
157_A	224_K	1.006	1.00
194_G	206_V	1.006	1.00
159_A	163_R	1.002	1.00
61_E	457_M	1.001	1.00
220_L	224_K	1.000	1.00
257_E	261_R	0.999	1.00
274_Y	277_S	0.998	1.00
294_D	297_D	0.996	1.00
68_R	458_K	0.995	1.00
165_K	232_F	0.990	1.00
451_N	458_K	0.985	1.00
100_A	155_N	0.984	1.00
133_M	143_G	0.979	1.00
252_D	320_S	0.979	1.00
261_R	279_A	0.977	1.00
93_I	159_A	0.973	0.99
281_K	284_E	0.972	0.99
398_I	467_W	0.972	0.99
358_L	375_I	0.972	0.99
125_V	170_Y	0.970	0.99
345_T	403_S	0.964	0.99
150_V	220_L	0.962	0.99
235_G	309_G	0.961	0.99
152_F	155_N	0.960	0.99
253_V	256_A	0.957	0.99
28_K	91_S	0.955	0.99
259_E	318_V	0.955	0.99
204_K	286_E	0.951	0.99
82_K	475_N	0.951	0.99
9_L	125_V	0.948	0.99
125_V	374_F	0.941	0.99
7_D	420_I	0.937	0.99
160_C	164_Y	0.935	0.99
147_R	293_E	0.933	0.99
19_F	65_F	0.932	0.99
158_E	229_N	0.932	0.99
428_I	447_V	0.929	0.99
254_M	257_E	0.921	0.99
222_V	234_I	0.921	0.99
383_V	439_K	0.919	0.99
161_F	232_F	0.917	0.99
142_G	145_R	0.915	0.99
221_A	224_K	0.914	0.99
386_L	391_K	0.913	0.99
441_R	449_R	0.912	0.99
340_E	346_S	0.910	0.99
382_A	396_E	0.909	0.99
112_D	115_D	0.909	0.99
181_M	210_T	0.906	0.99
108_Q	111_D	0.901	0.99
157_A	161_F	0.898	0.99
27_G	103_N	0.895	0.99
257_E	278_Y	0.895	0.99
138_A	194_G	0.894	0.99
271_V	371_I	0.889	0.99
243_I	256_A	0.887	0.99
268_D	369_Y	0.881	0.99
156_F	160_C	0.880	0.99
238_V	267_P	0.878	0.99
166_D	232_F	0.876	0.99
235_G	307_Y	0.874	0.99
71_E	74_A	0.872	0.99
203_A	206_V	0.872	0.99
141_Y	149_V	0.870	0.99
471_V	475_N	0.868	0.99
260_M	264_Y	0.867	0.99
358_L	407_A	0.864	0.99
165_K	229_N	0.861	0.99
129_S	133_M	0.859	0.99
439_K	451_N	0.859	0.99
135_L	138_A	0.858	0.99
381_G	440_K	0.854	0.99
163_R	167_K	0.854	0.99
109_F	113_V	0.854	0.99
32_V	138_A	0.852	0.99
223_A	299_I	0.851	0.99
107_L	160_C	0.851	0.99
380_F	396_E	0.850	0.99
111_D	114_F	0.847	0.99
295_G	299_I	0.846	0.99
346_S	352_A	0.845	0.99
412_V	419_L	0.845	0.99
406_E	410_K	0.845	0.99
466_E	470_N	0.843	0.99
218_S	222_V	0.843	0.99
81_L	427_I	0.842	0.99
97_G	136_H	0.842	0.99
356_T	410_K	0.840	0.99
392_V	460_Y	0.839	0.98
248_S	253_V	0.839	0.98
315_S	352_A	0.838	0.98
74_A	77_A	0.838	0.98
3_N	6_K	0.836	0.98
118_L	124_P	0.835	0.98
310_F	373_L	0.833	0.98
150_V	216_V	0.833	0.98
172_M	309_G	0.828	0.98
363_N	367_D	0.828	0.98
395_P	399_Q	0.827	0.98
205_E	290_I	0.826	0.98
386_L	390_G	0.825	0.98
76_F	122_I	0.821	0.98
366_Y	370_Q	0.818	0.98
10_W	405_I	0.814	0.98
240_H	310_F	0.810	0.98
129_S	132_E	0.809	0.98
319_K	337_N	0.807	0.98
281_K	285_R	0.805	0.98
179_N	239_S	0.805	0.98
174_F	180_Q	0.803	0.98
98_D	140_E	0.801	0.98
282_E	286_E	0.800	0.98
173_T	236_A	0.796	0.98
359_R	407_A	0.796	0.98
315_S	354_D	0.795	0.98
315_S	357_G	0.793	0.98
78_E	469_K	0.792	0.98
349_W	440_K	0.792	0.98
51_I	439_K	0.790	0.98
451_N	457_M	0.788	0.98
354_D	357_G	0.786	0.98
246_F	252_D	0.784	0.98
314_M	352_A	0.783	0.98
16_A	89_G	0.782	0.98
5_P	418_D	0.782	0.98
173_T	218_S	0.779	0.98
81_L	468_Y	0.779	0.98
249_N	252_D	0.779	0.98
146_N	152_F	0.778	0.98
19_F	63_I	0.778	0.98
220_L	223_A	0.777	0.98
159_A	162_T	0.776	0.97
363_N	366_Y	0.771	0.97
153_F	157_A	0.770	0.97
9_L	123_E	0.768	0.97
61_E	64_D	0.768	0.97
93_I	160_C	0.767	0.97
69_Y	73_I	0.767	0.97
362_L	419_L	0.766	0.97
102_P	107_L	0.765	0.97
205_E	209_Q	0.765	0.97
387_E	390_G	0.764	0.97
32_V	133_M	0.764	0.97
104_E	111_D	0.761	0.97
347_S	380_F	0.760	0.97
463_D	466_E	0.757	0.97
209_Q	291_T	0.753	0.97
165_K	228_I	0.749	0.97
28_K	31_S	0.747	0.97
366_Y	417_V	0.743	0.97
124_P	169_K	0.742	0.97
77_A	121_G	0.741	0.97
271_V	308_L	0.739	0.97
277_S	280_L	0.739	0.97
243_I	318_V	0.736	0.97
353_I	382_A	0.734	0.97
89_G	132_E	0.734	0.97
79_M	461_K	0.733	0.96
271_V	305_V	0.731	0.96
106_G	109_F	0.729	0.96
257_E	364_R	0.725	0.96
373_L	417_V	0.723	0.96
385_T	388_E	0.721	0.96
430_I	442_Y	0.718	0.96
211_A	265_F	0.718	0.96
126_I	168_V	0.718	0.96
173_T	234_I	0.717	0.96
445_I	461_K	0.717	0.96
192_N	195_V	0.716	0.96
411_A	417_V	0.716	0.96
371_I	418_D	0.714	0.96
98_D	136_H	0.714	0.96
59_N	62_A	0.706	0.96
3_N	409_K	0.704	0.96
349_W	381_G	0.703	0.96
215_L	270_Q	0.703	0.96
341_N	344_I	0.701	0.95
138_A	145_R	0.699	0.95
345_T	396_E	0.697	0.95
179_N	183_V	0.696	0.95
22_G	66_Y	0.696	0.95
356_T	359_R	0.694	0.95
7_D	475_N	0.693	0.95
14_L	428_I	0.693	0.95
338_G	342_P	0.693	0.95
161_F	228_I	0.693	0.95
117_L	120_H	0.690	0.95
242_P	360_Y	0.690	0.95
26_G	66_Y	0.689	0.95
118_L	123_E	0.688	0.95
98_D	155_N	0.687	0.95
23_W	60_H	0.686	0.95
215_L	300_L	0.685	0.95
253_V	257_E	0.685	0.95
94_F	101_E	0.685	0.95
398_I	463_D	0.684	0.95
10_W	82_K	0.684	0.95
279_A	283_F	0.683	0.95
30_P	38_A	0.683	0.95
254_M	356_T	0.683	0.95
274_Y	297_D	0.682	0.95
19_F	430_I	0.682	0.95
145_R	210_T	0.681	0.95
72_D	459_R	0.681	0.95
178_N	239_S	0.679	0.95
405_I	424_P	0.679	0.95
284_E	289_N	0.678	0.95
96_K	100_A	0.677	0.95
217_A	221_A	0.677	0.95
24_N	30_P	0.676	0.94
432_S	442_Y	0.675	0.94
48_T	51_I	0.675	0.94
310_F	365_F	0.673	0.94
158_E	227_D	0.668	0.94
51_I	58_P	0.668	0.94
147_R	295_G	0.667	0.94
237_M	311_S	0.666	0.94
96_K	140_E	0.665	0.94
444_M	468_Y	0.663	0.94
471_V	474_T	0.661	0.94
76_F	427_I	0.660	0.94
240_H	267_P	0.659	0.94
68_R	457_M	0.659	0.94
114_F	168_V	0.658	0.94
79_M	444_M	0.657	0.94
118_L	169_K	0.655	0.94
213_H	293_E	0.655	0.94
345_T	399_Q	0.654	0.93
244_Y	315_S	0.654	0.93
431_V	437_E	0.652	0.93
311_S	376_V	0.652	0.93
59_N	436_G	0.651	0.93
147_R	216_V	0.646	0.93
38_A	43_V	0.646	0.93
157_A	160_C	0.646	0.93
240_H	264_Y	0.644	0.93
190_W	194_G	0.643	0.93
82_K	123_E	0.642	0.93
86_T	117_L	0.642	0.93
23_W	89_G	0.641	0.93
362_L	411_A	0.640	0.93
162_T	224_K	0.640	0.93
308_L	371_I	0.639	0.93
151_D	155_N	0.638	0.93
195_V	203_A	0.638	0.93
255_L	259_E	0.637	0.93
219_A	300_L	0.637	0.93
145_R	209_Q	0.637	0.93
205_E	289_N	0.636	0.93
238_V	266_F	0.636	0.93
47_I	51_I	0.635	0.92
168_V	171_W	0.634	0.92
153_F	174_F	0.633	0.92
160_C	171_W	0.633	0.92
70_K	74_A	0.632	0.92
73_I	122_I	0.632	0.92
11_G	423_T	0.630	0.92
9_L	82_K	0.628	0.92
30_P	135_L	0.627	0.92
118_L	121_G	0.626	0.92
294_D	298_E	0.626	0.92
457_M	461_K	0.626	0.92
249_N	320_S	0.626	0.92
212_H	292_F	0.625	0.92
202_N	205_E	0.624	0.92
117_L	121_G	0.624	0.92
155_N	159_A	0.624	0.92
312_Y	358_L	0.624	0.92
405_I	471_V	0.623	0.92
145_R	194_G	0.623	0.92
410_K	415_D	0.622	0.92
125_V	172_M	0.621	0.92
246_F	317_T	0.620	0.92
222_V	305_V	0.620	0.92
431_V	449_R	0.619	0.91
391_K	460_Y	0.619	0.91
85_R	175_N	0.619	0.91
4_M	475_N	0.616	0.91
372_P	418_D	0.615	0.91
233_Q	420_I	0.615	0.91
129_S	180_Q	0.614	0.91
408_L	412_V	0.614	0.91
13_A	423_T	0.614	0.91
223_A	304_T	0.613	0.91
88_I	114_F	0.613	0.91
281_K	410_K	0.611	0.91
209_Q	213_H	0.611	0.91
43_V	47_I	0.610	0.91
386_L	392_V	0.610	0.91
427_I	445_I	0.608	0.91
208_Y	283_F	0.606	0.91
93_I	107_L	0.605	0.91
321_D	324_N	0.605	0.91
446_Y	462_K	0.604	0.90
94_F	155_N	0.604	0.90
374_F	421_G	0.604	0.90
107_L	164_Y	0.604	0.90
97_G	137_L	0.603	0.90
446_Y	458_K	0.603	0.90
390_G	458_K	0.602	0.90
273_G	302_N	0.602	0.90
150_V	217_A	0.600	0.90
128_L	161_F	0.600	0.90
137_L	152_F	0.599	0.90
247_S	319_K	0.598	0.90
391_K	466_E	0.596	0.90
82_K	472_I	0.595	0.90
395_P	398_I	0.594	0.90
348_D	382_A	0.590	0.89
30_P	91_S	0.589	0.89
75_L	428_I	0.588	0.89
348_D	440_K	0.587	0.89
219_A	304_T	0.584	0.89
112_D	116_E	0.584	0.89
262_Q	279_A	0.583	0.89
228_I	232_F	0.583	0.89
261_R	364_R	0.582	0.89
75_L	445_I	0.582	0.89
194_G	203_A	0.581	0.89
37_T	431_V	0.579	0.89
223_A	226_K	0.577	0.88
342_P	345_T	0.576	0.88
96_K	152_F	0.573	0.88
365_F	373_L	0.572	0.88
7_D	412_V	0.572	0.88
84_L	117_L	0.571	0.88
37_T	43_V	0.571	0.88
336_P	340_E	0.571	0.88
430_I	433_F	0.569	0.88
14_L	427_I	0.569	0.88
136_H	152_F	0.569	0.88
150_V	154_V	0.568	0.88
80_G	469_K	0.566	0.87
240_H	365_F	0.564	0.87
170_Y	374_F	0.564	0.87
346_S	350_G	0.564	0.87
235_G	374_F	0.563	0.87
380_F	384_D	0.562	0.87
299_I	303_G	0.562	0.87
279_A	282_E	0.561	0.87
62_A	457_M	0.560	0.87
79_M	465_F	0.560	0.87
29_G	94_F	0.560	0.87
202_N	206_V	0.559	0.87
4_M	10_W	0.559	0.87
115_D	166_D	0.558	0.87
242_P	260_M	0.558	0.87
65_F	76_F	0.556	0.87
265_F	283_F	0.556	0.87
115_D	119_K	0.556	0.87
219_A	303_G	0.555	0.86
245_P	252_D	0.555	0.86
128_L	157_A	0.555	0.86
47_I	431_V	0.554	0.86
190_W	193_S	0.554	0.86
19_F	84_L	0.554	0.86
258_E	320_S	0.554	0.86
125_V	420_I	0.553	0.86
241_V	316_T	0.552	0.86
293_E	297_D	0.552	0.86
349_W	435_T	0.552	0.86
386_L	389_D	0.551	0.86
373_L	419_L	0.551	0.86
218_S	270_Q	0.547	0.86
70_K	73_I	0.546	0.86
78_E	466_E	0.544	0.85
77_A	119_K	0.543	0.85
374_F	423_T	0.543	0.85
313_Y	377_E	0.540	0.85
292_F	295_G	0.540	0.85
347_S	350_G	0.539	0.85
267_P	365_F	0.539	0.85
244_Y	354_D	0.539	0.85
141_Y	146_N	0.536	0.84
37_T	59_N	0.535	0.84
216_V	299_I	0.535	0.84
426_G	430_I	0.534	0.84
48_T	435_T	0.534	0.84
191_T	195_V	0.534	0.84
133_M	138_A	0.532	0.84
32_V	129_S	0.531	0.84
61_E	67_H	0.531	0.84
360_Y	363_N	0.531	0.84
387_E	460_Y	0.530	0.84
23_W	38_A	0.529	0.84
14_L	65_F	0.528	0.84
376_V	420_I	0.528	0.84
441_R	446_Y	0.528	0.84
65_F	73_I	0.526	0.83
347_S	381_G	0.526	0.83
22_G	28_K	0.525	0.83
401_L	405_I	0.524	0.83
94_F	98_D	0.524	0.83
7_D	82_K	0.522	0.83
81_L	122_I	0.522	0.83
392_V	446_Y	0.521	0.83
309_G	376_V	0.520	0.83
49_D	439_K	0.520	0.83
291_T	295_G	0.520	0.83
347_S	382_A	0.518	0.82
410_K	413_T	0.517	0.82
17_H	37_T	0.516	0.82
76_F	84_L	0.513	0.82
144_F	174_F	0.512	0.82
137_L	149_V	0.511	0.82
407_A	415_D	0.511	0.82
280_L	297_D	0.510	0.81
65_F	69_Y	0.509	0.81
267_P	271_V	0.509	0.81
437_E	451_N	0.508	0.81
398_I	402_K	0.508	0.81
14_L	430_I	0.508	0.81
426_G	449_R	0.508	0.81
425_W	430_I	0.507	0.81
222_V	303_G	0.507	0.81
213_H	291_T	0.507	0.81
138_A	143_G	0.506	0.81
247_S	253_V	0.505	0.81
173_T	221_A	0.503	0.81
33_V	433_F	0.503	0.81
241_V	263_R	0.503	0.81
268_D	274_Y	0.503	0.81
445_I	465_F	0.503	0.81
450_D	458_K	0.502	0.80
33_V	36_M	0.502	0.80
127_T	237_M	0.502	0.80
9_L	170_Y	0.502	0.80
185_N	210_T	0.501	0.80
165_K	230_P	0.501	0.80
338_G	341_N	0.500	0.80
435_T	440_K	0.500	0.80

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1v02A	2	0.9499	100	0.125	Contact Map
2jf7A	5	0.9415	100	0.126	Contact Map
3ptmA	1	0.952	100	0.127	Contact Map
3wq5A	1	0.952	100	0.129	Contact Map
2dgaA	5	0.9562	100	0.13	Contact Map
1v08A	2	0.952	100	0.132	Contact Map
1cbgA	2	0.952	100	0.134	Contact Map
3f5lA	2	0.9457	100	0.136	Contact Map
4f66A	2	0.9791	100	0.136	Contact Map
3viiA	2	0.9395	100	0.139	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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