GREMLIN Database
RL10 - 50S ribosomal protein L10
UniProt: P42923 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 166 (157)
Sequences: 2981 (1722)
Seq/√Len: 137.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
119_T122_E3.5941.00
75_F110_A3.0501.00
18_K51_E2.9861.00
155_K158_A2.7421.00
155_K159_E2.7081.00
21_E86_T2.5721.00
5_I9_K2.5481.00
16_A20_K2.5401.00
62_R65_E2.4351.00
40_E44_Q2.2861.00
148_R152_L2.2571.00
132_R136_L2.2561.00
17_S21_E2.1861.00
121_E124_K2.1451.00
16_A66_Q2.1361.00
98_D102_N2.0281.00
44_Q47_E2.0261.00
134_G138_M1.9641.00
116_K122_E1.9561.00
44_Q98_D1.9551.00
124_K128_E1.9421.00
37_E103_H1.8891.00
113_I118_S1.7261.00
15_I55_Y1.7231.00
158_A161_K1.7221.00
97_N128_E1.7151.00
29_D107_E1.6361.00
157_V161_K1.6331.00
142_V145_A1.6171.00
6_E9_K1.6161.00
156_A159_E1.6121.00
13_E17_S1.6071.00
97_N124_K1.6061.00
65_E70_N1.6041.00
44_Q102_N1.6021.00
34_N37_E1.5881.00
49_N87_E1.5361.00
99_F103_H1.4851.00
138_M141_S1.4621.00
149_N152_L1.4491.00
17_S20_K1.4431.00
28_V52_F1.3801.00
131_S135_L1.3381.00
28_V81_A1.3291.00
61_R73_N1.3191.00
98_D101_K1.3161.00
120_V124_K1.3121.00
29_D109_K1.2981.00
45_L50_V1.2781.00
43_K47_E1.2641.00
55_Y60_T1.2561.00
10_V13_E1.2501.00
140_L143_L1.2421.00
31_R79_P1.2381.00
139_L143_L1.2361.00
60_T82_I1.2291.00
52_F83_A1.2191.00
18_K84_F1.2151.00
52_F81_A1.2131.00
38_V52_F1.2101.00
131_S134_G1.2101.00
16_A67_A1.1961.00
71_G117_V1.1790.99
122_E125_A1.1780.99
150_L154_A1.1720.99
9_K12_V1.1690.99
65_E73_N1.1480.99
19_L60_T1.1450.99
41_L99_F1.1420.99
19_L64_V1.1330.99
9_K13_E1.1320.99
90_V94_K1.1270.99
133_E136_L1.1150.99
137_S141_S1.1060.99
80_N109_K1.0820.99
149_N153_A1.0800.99
7_T10_V1.0790.99
88_D91_A1.0770.99
70_N73_N1.0720.99
152_L155_K1.0510.99
27_I72_L1.0380.99
139_L142_V1.0270.99
97_N127_A1.0080.98
6_E10_V1.0080.98
33_L106_L1.0040.98
48_A95_V0.9850.98
40_E102_N0.9750.98
36_S40_E0.9690.98
45_L81_A0.9650.98
151_A155_K0.9580.98
29_D80_N0.9500.98
140_L144_Q0.9470.98
136_L140_L0.9460.98
10_V14_E0.9440.98
15_I60_T0.9430.98
137_S140_L0.9310.97
45_L96_L0.9140.97
50_V83_A0.9090.97
60_T80_N0.8930.97
14_E53_K0.8930.97
26_I83_A0.8570.96
85_S92_P0.8480.95
153_A157_V0.8470.95
152_L156_A0.8450.95
37_E105_A0.8450.95
145_A149_N0.8280.95
58_T61_R0.8170.94
66_Q70_N0.8160.94
11_V59_M0.8070.94
19_L84_F0.8060.94
35_V39_T0.8040.94
97_N108_I0.7990.94
45_L95_V0.7920.93
76_L82_I0.7910.93
23_K87_E0.7910.93
14_E18_K0.7870.93
140_L151_A0.7810.93
124_K127_A0.7730.93
125_A128_E0.7690.92
139_L150_L0.7670.92
51_E86_T0.7670.92
7_T11_V0.7640.92
5_I12_V0.7610.92
142_V146_P0.7540.92
38_V81_A0.7530.92
157_V160_Q0.7400.91
83_A96_L0.7390.91
41_L103_H0.7370.91
37_E40_E0.7350.91
149_N156_A0.7340.91
13_E16_A0.7320.90
48_A91_A0.7260.90
19_L25_T0.7260.90
45_L92_P0.7200.90
27_I80_N0.7170.90
101_K128_E0.7160.89
8_K12_V0.7160.89
152_L161_K0.7160.89
69_L112_V0.7140.89
71_G74_D0.7120.89
60_T64_V0.7100.89
23_K114_E0.7070.89
33_L103_H0.7070.89
43_K46_R0.7030.89
75_F117_V0.6940.88
150_L157_V0.6920.88
83_A93_A0.6920.88
24_S85_S0.6860.87
111_G123_V0.6840.87
49_N86_T0.6800.87
107_E120_V0.6730.86
25_T82_I0.6730.86
152_L159_E0.6670.86
12_V59_M0.6660.86
50_V95_V0.6650.86
40_E103_H0.6650.86
140_L146_P0.6560.85
55_Y59_M0.6530.85
138_M142_V0.6520.85
96_L106_L0.6520.85
25_T64_V0.6430.84
61_R77_T0.6420.84
28_V106_L0.6380.83
13_E66_Q0.6350.83
96_L108_I0.6330.83
27_I110_A0.6300.83
5_I62_R0.6300.83
100_A103_H0.6280.82
61_R74_D0.6280.82
45_L52_F0.6280.82
26_I85_S0.6250.82
143_L148_R0.6220.82
154_A158_A0.6220.82
103_H107_E0.6160.81
33_L37_E0.6150.81
50_V92_P0.6140.81
57_N109_K0.6130.81
153_A156_A0.6110.81
36_S39_T0.6040.80
44_Q48_A0.6000.79
97_N101_K0.5980.79
11_V14_E0.5940.79
18_K86_T0.5930.79
74_D77_T0.5900.78
76_L80_N0.5870.78
64_V67_A0.5850.78
155_K161_K0.5830.77
29_D82_I0.5800.77
44_Q95_V0.5790.77
148_R161_K0.5790.77
20_K68_E0.5780.77
141_S145_A0.5750.76
48_A94_K0.5740.76
21_E51_E0.5710.76
100_A106_L0.5690.76
15_I19_L0.5690.76
30_Y38_V0.5690.76
15_I84_F0.5660.75
72_L80_N0.5650.75
64_V68_E0.5620.75
118_S126_L0.5610.75
88_D95_V0.5580.74
72_L109_K0.5560.74
35_V38_V0.5560.74
50_V59_M0.5530.74
29_D105_A0.5490.73
72_L76_L0.5440.72
21_E87_E0.5390.72
108_I123_V0.5380.72
147_V158_A0.5380.72
139_L146_P0.5360.71
5_I8_K0.5330.71
64_V76_L0.5330.71
141_S148_R0.5330.71
128_E134_G0.5320.71
55_Y82_I0.5310.71
152_L158_A0.5300.71
57_N80_N0.5290.70
22_S84_F0.5250.70
85_S110_A0.5250.70
11_V58_T0.5250.70
64_V73_N0.5240.70
140_L149_N0.5230.70
50_V85_S0.5220.69
126_L129_L0.5190.69
23_K131_S0.5150.68
72_L117_V0.5140.68
144_Q147_V0.5140.68
118_S122_E0.5130.68
22_S25_T0.5130.68
143_L147_V0.5070.67
130_P135_L0.5070.67
30_Y33_L0.5050.67
98_D134_G0.5030.67
113_I123_V0.5020.66
130_P138_M0.5000.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4kix5 1 0.8916 100 0.121 Contact Map
1zavA 1 0.9699 100 0.174 Contact Map
3j7yI 1 0.7289 100 0.179 Contact Map
1vq8G 1 0 99.9 0.529 Contact Map
3j65n 1 0.988 99.9 0.534 Contact Map
3a1yG 1 0.6145 99.9 0.534 Contact Map
4hubG 1 0.9518 99.9 0.535 Contact Map
3j21k 1 0.9277 99.9 0.545 Contact Map
4nwbA 2 0.9217 99.9 0.556 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0069 seconds.