NASC - BACSU - GREMLIN Contacts

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NASC - Assimilatory nitrate reductase catalytic subunit

UniProt:	P42434	Sequences: MTERLLRYFRDKQQDVQSEKTYDTQCPFCSMQCKMQLVEQTIVTRKKYTAIGIDNPTTQGRLCIKGMNAHQHALNSSRITRPLLKKNGEFMPVSWEEALNHIKDQVTMIQTEHGHDAMAVYGSASITNEEAYLLGKFARVGLQTKYIDYNGRLCMSAAATAANQTFGADRGLTNPLSDIPHTRVIILAGTNIAECQPTIMPYFEKAKENGAYFIAIDPRETATTKIADLHLKIKPGTDAALANGLVKIIIDEQLINEDFIQSRTNGFEELKQHTDSLDLNDIAEQTSVSLVDIRKAAVKFAKETSGMLFTARGIEQQTDGTAAVKGFLNMVLITGKIGKPYSGYGAITGQGNGQGAREHGQKADQLPGYRSIENEEHRAHIAKVWGIHQDELPRKGVSAYEMMEKINDGDIKGLFLMCSNPAVSSPNANLVKKALRRLTFFVAIDLFISETAKYADVILPASSYLEDEGTMTNVEGRVTLREASRPCPGEAKHDWQIICDLASALGKGRYFSYTSAEDIFNELREASRGGIADYSGISYGRLRREGGIHWPCPESDHPGTGRLFTESFAHPDQKAALSVIPNEPPVPKEKPTADYPLYLTTGRVMSHYLTGVQTRKSAALAARHFESFMEIHPQTAATYNIEDRVLVKIESPRGSITVRSKLSEQIRKDTVFVPIHWADAQNVNDLIGEALDPACKMPGFKVCAVRIIPI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	710 (666)
Sequences:	9579 (5837)
Seq/√Len:	226.2

ECOLI - FDHF DMSA NAPA YNFF TORA YNFE TORZ YDEP BISC FDOG FDNG NUOG NARG NARZ
BACSU - NASC YJGC YOAE FDHL YYAE NARG
HALSA - DMSA
SULSO - Q97ZA1 Q97V13 Q97XX8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
81_R	92_P	5.634	1.00
641_I	660_S	4.546	1.00
100_N	504_A	4.393	1.00
648_K	708_I	4.022	1.00
492_K	500_D	3.692	1.00
252_E	298_V	3.404	1.00
648_K	655_S	3.329	1.00
244_G	282_I	3.208	1.00
280_N	290_L	3.188	1.00
597_L	639_Y	3.183	1.00
105_Q	108_M	3.164	1.00
635_T	669_D	3.119	1.00
496_Q	500_D	3.098	1.00
634_Q	668_K	2.988	1.00
483_A	486_P	2.983	1.00
248_I	252_E	2.921	1.00
257_E	261_Q	2.914	1.00
101_H	457_V	2.905	1.00
265_N	572_D	2.847	1.00
247_K	251_D	2.828	1.00
246_V	270_L	2.776	1.00
188_A	242_A	2.738	1.00
94_S	97_E	2.722	1.00
650_E	708_I	2.690	1.00
515_S	518_D	2.689	1.00
99_L	504_A	2.688	1.00
102_I	457_V	2.671	1.00
283_A	290_L	2.666	1.00
443_A	455_A	2.628	1.00
650_E	706_R	2.591	1.00
108_M	112_E	2.568	1.00
572_D	576_A	2.567	1.00
212_Y	299_K	2.538	1.00
246_V	333_I	2.534	1.00
109_I	117_A	2.527	1.00
241_L	286_T	2.502	1.00
647_V	660_S	2.472	1.00
289_S	292_D	2.464	1.00
229_L	295_K	2.463	1.00
651_S	705_V	2.460	1.00
631_I	660_S	2.459	1.00
292_D	295_K	2.446	1.00
81_R	490_E	2.445	1.00
626_E	659_R	2.443	1.00
290_L	294_R	2.440	1.00
183_R	305_S	2.429	1.00
215_A	227_A	2.422	1.00
93_V	457_V	2.421	1.00
631_I	707_I	2.419	1.00
638_T	668_K	2.413	1.00
84_L	101_H	2.392	1.00
636_A	662_L	2.388	1.00
650_E	655_S	2.385	1.00
99_L	500_D	2.366	1.00
278_D	281_D	2.339	1.00
255_I	260_I	2.321	1.00
84_L	93_V	2.288	1.00
84_L	457_V	2.285	1.00
250_I	267_F	2.267	1.00
181_H	340_P	2.243	1.00
253_Q	257_E	2.227	1.00
258_D	262_S	2.206	1.00
182_T	185_I	2.157	1.00
106_V	413_G	2.150	1.00
412_K	439_T	2.113	1.00
643_D	662_L	2.112	1.00
102_I	442_V	2.085	1.00
500_D	504_A	2.083	1.00
639_Y	706_R	2.076	1.00
184_V	299_K	2.044	1.00
641_I	647_V	2.020	1.00
231_L	296_A	2.017	1.00
629_M	671_V	2.007	1.00
295_K	299_K	1.990	1.00
231_L	288_V	1.981	1.00
629_M	647_V	1.970	1.00
101_H	105_Q	1.968	1.00
92_P	490_E	1.923	1.00
109_I	413_G	1.915	1.00
229_L	292_D	1.908	1.00
488_P	491_A	1.902	1.00
538_S	541_R	1.900	1.00
241_L	293_I	1.885	1.00
629_M	649_I	1.875	1.00
206_A	211_A	1.873	1.00
646_L	657_T	1.869	1.00
648_K	657_T	1.869	1.00
93_V	101_H	1.853	1.00
207_K	228_D	1.839	1.00
597_L	671_V	1.833	1.00
247_K	279_L	1.822	1.00
658_V	673_V	1.811	1.00
415_F	444_I	1.806	1.00
184_V	214_I	1.806	1.00
36_Q	53_I	1.797	1.00
237_T	285_Q	1.796	1.00
255_I	267_F	1.794	1.00
643_D	661_K	1.774	1.00
642_E	645_V	1.772	1.00
671_V	705_V	1.763	1.00
250_I	271_K	1.757	1.00
629_M	673_V	1.752	1.00
448_I	452_A	1.749	1.00
100_N	104_D	1.746	1.00
254_L	301_A	1.739	1.00
634_Q	637_A	1.732	1.00
339_K	342_S	1.721	1.00
252_E	294_R	1.720	1.00
541_R	545_E	1.719	1.00
41_T	44_T	1.716	1.00
229_L	299_K	1.712	1.00
631_I	671_V	1.705	1.00
84_L	91_M	1.699	1.00
248_I	294_R	1.690	1.00
282_I	293_I	1.677	1.00
432_K	436_R	1.672	1.00
514_T	518_D	1.664	1.00
300_F	306_G	1.659	1.00
468_E	483_A	1.650	1.00
260_I	267_F	1.644	1.00
80_T	489_G	1.638	1.00
248_I	279_L	1.628	1.00
272_Q	275_D	1.619	1.00
248_I	298_V	1.605	1.00
83_L	458_I	1.603	1.00
602_G	672_F	1.594	1.00
500_D	503_S	1.588	1.00
216_I	241_L	1.587	1.00
433_K	436_R	1.585	1.00
283_A	289_S	1.584	1.00
646_L	659_R	1.578	1.00
438_L	441_F	1.571	1.00
254_L	298_V	1.558	1.00
250_I	274_T	1.555	1.00
266_G	269_E	1.555	1.00
298_V	302_K	1.549	1.00
300_F	334_T	1.548	1.00
249_I	255_I	1.544	1.00
280_N	294_R	1.540	1.00
241_L	296_A	1.538	1.00
93_V	97_E	1.537	1.00
34_K	55_N	1.529	1.00
22_Y	39_E	1.522	1.00
597_L	635_T	1.513	1.00
379_A	383_K	1.498	1.00
249_I	301_A	1.493	1.00
186_I	296_A	1.493	1.00
630_E	663_S	1.491	1.00
240_A	285_Q	1.491	1.00
283_A	293_I	1.490	1.00
462_S	493_H	1.481	1.00
107_T	111_T	1.477	1.00
333_I	577_L	1.476	1.00
440_F	457_V	1.474	1.00
117_A	412_K	1.473	1.00
264_T	577_L	1.472	1.00
229_L	296_A	1.464	1.00
138_A	144_T	1.457	1.00
97_E	101_H	1.456	1.00
104_D	108_M	1.451	1.00
265_N	576_A	1.442	1.00
186_I	216_I	1.439	1.00
102_I	459_L	1.430	1.00
71_Q	619_A	1.426	1.00
113_H	412_K	1.419	1.00
656_I	673_V	1.416	1.00
82_P	95_W	1.411	1.00
83_L	92_P	1.399	1.00
184_V	296_A	1.397	1.00
269_E	272_Q	1.389	1.00
427_N	689_E	1.387	1.00
540_G	544_R	1.385	1.00
492_K	496_Q	1.379	1.00
24_T	37_L	1.379	1.00
443_A	452_A	1.370	1.00
553_P	557_H	1.361	1.00
23_D	36_Q	1.352	1.00
251_D	275_D	1.351	1.00
237_T	286_T	1.350	1.00
448_I	458_I	1.348	1.00
38_V	50_A	1.348	1.00
106_V	442_V	1.346	1.00
248_I	251_D	1.346	1.00
251_D	294_R	1.337	1.00
303_E	306_G	1.329	1.00
231_L	292_D	1.328	1.00
245_L	296_A	1.328	1.00
416_L	441_F	1.327	1.00
314_I	327_F	1.324	1.00
446_L	463_S	1.319	1.00
119_A	411_I	1.319	1.00
258_D	261_Q	1.311	1.00
248_I	254_L	1.310	1.00
407_N	430_L	1.308	1.00
267_F	271_K	1.306	1.00
120_V	138_A	1.301	1.00
592_T	652_P	1.298	1.00
597_L	706_R	1.293	1.00
37_L	46_K	1.288	1.00
639_Y	707_I	1.286	1.00
521_N	524_R	1.278	1.00
99_L	492_K	1.274	1.00
281_D	284_E	1.272	1.00
218_P	230_H	1.268	1.00
493_H	496_Q	1.265	1.00
101_H	440_F	1.263	1.00
215_A	224_T	1.261	1.00
247_K	275_D	1.259	1.00
245_L	300_F	1.257	1.00
277_L	281_D	1.255	1.00
277_L	285_Q	1.255	1.00
629_M	658_V	1.248	1.00
233_I	288_V	1.244	1.00
110_Q	118_M	1.237	1.00
103_K	504_A	1.237	1.00
287_S	667_R	1.233	1.00
444_I	497_I	1.233	1.00
570_H	576_A	1.232	1.00
183_R	303_E	1.226	1.00
632_H	668_K	1.224	1.00
482_E	543_R	1.222	1.00
336_K	342_S	1.222	1.00
517_E	521_N	1.219	1.00
633_P	664_E	1.216	1.00
277_L	282_I	1.211	1.00
503_S	508_G	1.208	1.00
250_I	255_I	1.207	1.00
444_I	461_A	1.205	1.00
97_E	457_V	1.205	1.00
628_F	661_K	1.205	1.00
246_V	274_T	1.202	1.00
37_L	49_T	1.201	1.00
594_D	706_R	1.195	1.00
86_K	91_M	1.192	1.00
257_E	271_K	1.191	1.00
430_L	433_K	1.190	1.00
23_D	52_G	1.190	1.00
245_L	297_A	1.187	1.00
107_T	110_Q	1.186	1.00
183_R	304_T	1.186	1.00
233_I	237_T	1.184	1.00
673_V	683_V	1.179	1.00
245_L	249_I	1.175	1.00
520_F	524_R	1.172	1.00
119_A	402_M	1.168	1.00
161_A	324_V	1.160	1.00
518_D	521_N	1.159	1.00
178_D	181_H	1.158	1.00
417_M	498_I	1.156	1.00
186_I	245_L	1.155	1.00
36_Q	50_A	1.154	1.00
118_M	413_G	1.147	1.00
401_E	404_E	1.144	1.00
427_N	430_L	1.144	1.00
404_E	430_L	1.142	1.00
663_S	666_I	1.138	1.00
413_G	440_F	1.131	1.00
382_A	388_H	1.126	1.00
248_I	293_I	1.123	1.00
184_V	306_G	1.122	1.00
36_Q	52_G	1.120	1.00
214_I	296_A	1.119	1.00
480_L	543_R	1.117	1.00
160_T	694_A	1.114	1.00
77_S	616_K	1.111	1.00
276_S	281_D	1.111	1.00
205_K	208_E	1.110	1.00
242_A	327_F	1.110	1.00
254_L	302_K	1.109	1.00
249_I	334_T	1.107	1.00
398_S	401_E	1.105	1.00
267_F	333_I	1.105	1.00
496_Q	503_S	1.105	1.00
185_I	211_A	1.098	1.00
185_I	203_F	1.095	1.00
220_E	225_K	1.095	1.00
407_N	433_K	1.089	1.00
268_E	271_K	1.085	1.00
630_E	661_K	1.085	1.00
187_L	190_T	1.085	1.00
110_Q	115_H	1.082	1.00
594_D	652_P	1.080	1.00
85_K	90_F	1.079	1.00
649_I	673_V	1.075	1.00
136_K	139_R	1.073	1.00
283_A	286_T	1.068	1.00
403_M	406_I	1.068	1.00
413_G	442_V	1.063	1.00
374_N	377_H	1.062	1.00
184_V	303_E	1.062	1.00
105_Q	439_T	1.061	1.00
462_S	491_A	1.060	1.00
188_A	216_I	1.057	1.00
402_M	411_I	1.055	1.00
599_L	705_V	1.054	1.00
244_G	293_I	1.049	1.00
264_T	332_L	1.048	1.00
433_K	437_R	1.042	1.00
106_V	505_L	1.041	1.00
399_A	402_M	1.041	1.00
225_K	665_Q	1.039	1.00
245_L	330_M	1.037	1.00
270_L	274_T	1.034	1.00
220_E	665_Q	1.030	1.00
207_K	226_I	1.030	1.00
109_I	440_F	1.024	1.00
291_V	294_R	1.022	1.00
260_I	577_L	1.021	1.00
649_I	705_V	1.019	1.00
179_I	307_M	1.018	1.00
308_L	331_V	1.016	1.00
73_A	485_R	1.014	1.00
122_G	125_S	1.013	1.00
671_V	707_I	1.012	1.00
282_I	286_T	1.011	1.00
270_L	333_I	1.011	1.00
45_R	74_L	1.009	1.00
459_L	497_I	1.008	1.00
109_I	439_T	1.008	1.00
242_A	326_G	1.008	1.00
46_K	73_A	1.005	1.00
185_I	206_A	1.001	1.00
468_E	480_L	0.997	1.00
214_I	299_K	0.996	1.00
300_F	308_L	0.995	1.00
183_R	209_N	0.994	1.00
265_N	574_K	0.993	1.00
38_V	48_Y	0.992	1.00
271_K	275_D	0.990	1.00
110_Q	142_L	0.989	1.00
595_Y	706_R	0.988	1.00
629_M	707_I	0.988	1.00
631_I	641_I	0.987	1.00
416_L	451_T	0.984	1.00
402_M	406_I	0.982	1.00
216_I	231_L	0.982	1.00
114_G	117_A	0.981	1.00
86_K	89_E	0.978	1.00
596_P	706_R	0.976	1.00
422_A	428_A	0.974	1.00
212_Y	228_D	0.971	1.00
465_L	484_S	0.971	1.00
51_I	60_G	0.967	1.00
415_F	501_L	0.967	1.00
521_N	540_G	0.966	1.00
631_I	636_A	0.964	1.00
278_D	282_I	0.963	1.00
405_K	410_D	0.962	1.00
295_K	298_V	0.959	1.00
600_T	670_T	0.958	1.00
283_A	291_V	0.958	1.00
461_A	497_I	0.958	1.00
517_E	539_Y	0.957	1.00
105_Q	109_I	0.957	1.00
633_P	637_A	0.955	1.00
243_N	277_L	0.954	1.00
382_A	389_Q	0.954	1.00
288_V	293_I	0.954	1.00
332_L	575_A	0.953	1.00
630_E	665_Q	0.952	1.00
218_P	232_K	0.952	1.00
99_L	496_Q	0.951	1.00
632_H	666_I	0.951	1.00
531_I	535_S	0.946	1.00
305_S	339_K	0.946	1.00
247_K	278_D	0.943	1.00
244_G	248_I	0.943	1.00
49_T	70_H	0.942	1.00
239_A	323_A	0.942	1.00
294_R	298_V	0.942	1.00
235_P	670_T	0.941	1.00
248_I	297_A	0.941	1.00
102_I	440_F	0.940	1.00
80_T	92_P	0.940	1.00
306_G	336_K	0.940	1.00
118_M	142_L	0.938	1.00
165_T	325_K	0.938	1.00
563_L	566_E	0.936	1.00
95_W	459_L	0.935	1.00
422_A	432_K	0.934	1.00
234_K	667_R	0.933	1.00
281_D	285_Q	0.932	1.00
216_I	233_I	0.926	1.00
91_M	97_E	0.924	1.00
106_V	142_L	0.924	1.00
290_L	293_I	0.923	1.00
40_Q	47_K	0.923	1.00
80_T	488_P	0.919	1.00
34_K	52_G	0.917	1.00
180_P	202_Y	0.917	1.00
103_K	107_T	0.916	1.00
102_I	501_L	0.914	0.99
216_I	296_A	0.914	0.99
186_I	308_L	0.911	0.99
204_E	207_K	0.909	0.99
452_A	458_I	0.909	0.99
95_W	497_I	0.908	0.99
514_T	522_E	0.908	0.99
84_L	97_E	0.905	0.99
187_L	213_F	0.904	0.99
597_L	707_I	0.903	0.99
634_Q	664_E	0.902	0.99
90_F	458_I	0.900	0.99
632_H	662_L	0.899	0.99
44_T	486_P	0.898	0.99
247_K	274_T	0.894	0.99
595_Y	651_S	0.894	0.99
249_I	330_M	0.894	0.99
429_N	433_K	0.891	0.99
462_S	487_C	0.888	0.99
212_Y	229_L	0.888	0.99
436_R	454_Y	0.887	0.99
399_A	403_M	0.887	0.99
268_E	272_Q	0.887	0.99
37_L	465_L	0.886	0.99
96_E	504_A	0.885	0.99
79_I	458_I	0.885	0.99
123_S	126_I	0.883	0.99
468_E	516_A	0.880	0.99
270_L	577_L	0.880	0.99
279_L	282_I	0.879	0.99
233_I	241_L	0.877	0.99
99_L	501_L	0.876	0.99
255_I	333_I	0.875	0.99
288_V	292_D	0.875	0.99
401_E	405_K	0.874	0.99
635_T	668_K	0.874	0.99
192_I	203_F	0.874	0.99
106_V	415_F	0.872	0.99
214_I	229_L	0.871	0.99
377_H	380_H	0.871	0.99
243_N	273_H	0.870	0.99
116_D	145_K	0.868	0.99
521_N	525_E	0.866	0.99
517_E	543_R	0.866	0.99
256_N	339_K	0.866	0.99
23_D	54_D	0.866	0.99
102_I	105_Q	0.863	0.99
137_F	505_L	0.862	0.99
592_T	704_A	0.862	0.99
468_E	517_E	0.860	0.99
279_L	294_R	0.860	0.99
592_T	596_P	0.859	0.99
376_E	379_A	0.856	0.99
240_A	244_G	0.856	0.99
402_M	405_K	0.856	0.99
390_D	393_P	0.855	0.99
273_H	276_S	0.854	0.99
125_S	128_N	0.851	0.99
503_S	514_T	0.850	0.99
187_L	223_T	0.850	0.99
492_K	497_I	0.848	0.99
207_K	213_F	0.848	0.99
305_S	342_S	0.841	0.99
246_V	330_M	0.840	0.99
414_L	438_L	0.840	0.99
81_R	94_S	0.837	0.99
217_D	221_T	0.836	0.99
291_V	295_K	0.836	0.99
22_Y	484_S	0.836	0.99
627_S	677_W	0.834	0.99
653_R	703_C	0.833	0.99
314_I	323_A	0.832	0.99
241_L	245_L	0.831	0.99
184_V	212_Y	0.830	0.99
124_A	127_T	0.829	0.99
82_P	94_S	0.827	0.99
548_I	552_C	0.825	0.99
220_E	232_K	0.823	0.99
412_K	438_L	0.823	0.99
106_V	110_Q	0.822	0.99
184_V	300_F	0.821	0.99
35_M	62_L	0.821	0.99
636_A	641_I	0.818	0.99
420_N	610_T	0.817	0.99
656_I	686_L	0.817	0.99
220_E	664_E	0.815	0.99
292_D	299_K	0.814	0.99
164_Q	325_K	0.813	0.99
279_L	283_A	0.811	0.99
631_I	647_V	0.810	0.99
653_R	687_I	0.810	0.99
193_A	223_T	0.809	0.99
667_R	670_T	0.805	0.99
299_K	303_E	0.805	0.99
180_P	205_K	0.804	0.99
592_T	595_Y	0.802	0.99
407_N	437_R	0.798	0.99
477_R	549_H	0.798	0.99
381_I	385_W	0.796	0.99
83_L	448_I	0.795	0.99
397_V	405_K	0.795	0.99
232_K	667_R	0.794	0.99
531_I	534_Y	0.794	0.99
507_K	511_F	0.790	0.99
591_P	704_A	0.790	0.99
122_G	128_N	0.790	0.99
404_E	408_D	0.790	0.99
658_V	683_V	0.785	0.98
242_A	330_M	0.785	0.98
105_Q	440_F	0.785	0.98
449_S	452_A	0.784	0.98
80_T	83_L	0.784	0.98
233_I	286_T	0.784	0.98
99_L	103_K	0.784	0.98
123_S	127_T	0.783	0.98
312_R	316_Q	0.781	0.98
234_K	287_S	0.781	0.98
329_N	577_L	0.781	0.98
26_C	33_C	0.779	0.98
248_I	290_L	0.778	0.98
25_Q	479_T	0.778	0.98
576_A	579_V	0.777	0.98
123_S	128_N	0.777	0.98
29_C	33_C	0.774	0.98
243_N	274_T	0.774	0.98
251_D	279_L	0.773	0.98
164_Q	694_A	0.773	0.98
485_R	488_P	0.773	0.98
298_V	301_A	0.772	0.98
398_S	696_K	0.772	0.98
249_I	253_Q	0.771	0.98
463_S	488_P	0.771	0.98
617_S	620_L	0.770	0.98
652_P	704_A	0.770	0.98
93_V	98_A	0.769	0.98
244_G	281_D	0.768	0.98
165_T	578_S	0.767	0.98
429_N	685_D	0.765	0.98
478_V	537_I	0.764	0.98
44_T	47_K	0.762	0.98
656_I	685_D	0.760	0.98
252_E	301_A	0.759	0.98
380_H	383_K	0.757	0.98
400_Y	405_K	0.757	0.98
273_H	277_L	0.757	0.98
634_Q	638_T	0.756	0.98
231_L	241_L	0.755	0.98
244_G	279_L	0.755	0.98
239_A	326_G	0.752	0.98
631_I	662_L	0.751	0.98
283_A	288_V	0.750	0.98
499_C	503_S	0.748	0.98
308_L	327_F	0.748	0.98
416_L	443_A	0.747	0.98
244_G	278_D	0.747	0.98
279_L	290_L	0.747	0.98
122_G	127_T	0.745	0.98
95_W	492_K	0.744	0.98
508_G	512_S	0.744	0.98
85_K	88_G	0.743	0.98
40_Q	45_R	0.742	0.98
75_N	447_F	0.742	0.98
73_A	463_S	0.737	0.98
101_H	104_D	0.736	0.98
435_L	454_Y	0.735	0.98
413_G	457_V	0.733	0.98
244_G	284_E	0.732	0.98
260_I	264_T	0.731	0.98
116_D	144_T	0.731	0.98
104_D	107_T	0.731	0.98
161_A	328_L	0.731	0.98
178_D	341_Y	0.731	0.98
422_A	435_L	0.730	0.98
519_I	523_L	0.729	0.98
174_N	178_D	0.728	0.97
656_I	683_V	0.727	0.97
496_Q	499_C	0.727	0.97
348_T	351_G	0.725	0.97
318_T	699_G	0.724	0.97
22_Y	37_L	0.724	0.97
699_G	702_V	0.724	0.97
406_I	438_L	0.721	0.97
26_C	29_C	0.720	0.97
305_S	340_P	0.719	0.97
109_I	412_K	0.719	0.97
31_M	198_T	0.718	0.97
420_N	451_T	0.718	0.97
512_S	515_S	0.717	0.97
37_L	484_S	0.717	0.97
119_A	414_L	0.714	0.97
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599_L	673_V	0.713	0.97
260_I	333_I	0.713	0.97
380_H	384_V	0.712	0.97
483_A	487_C	0.711	0.97
450_E	678_A	0.711	0.97
468_E	482_E	0.710	0.97
597_L	669_D	0.709	0.97
534_Y	537_I	0.707	0.97
116_D	394_R	0.706	0.97
445_D	458_I	0.706	0.97
105_Q	413_G	0.704	0.97
140_V	507_K	0.703	0.97
690_A	699_G	0.702	0.97
636_A	663_S	0.701	0.97
270_L	273_H	0.701	0.97
51_I	62_L	0.698	0.97
522_E	526_A	0.697	0.97
429_N	432_K	0.697	0.97
166_F	328_L	0.694	0.97
495_W	519_I	0.692	0.97
99_L	102_I	0.691	0.97
41_T	45_R	0.690	0.97
571_P	576_A	0.690	0.97
100_N	103_K	0.690	0.97
520_F	523_L	0.690	0.97
422_A	454_Y	0.689	0.97
126_I	417_M	0.688	0.96
280_N	283_A	0.688	0.96
649_I	658_V	0.688	0.96
381_I	384_V	0.687	0.96
533_D	536_G	0.687	0.96
122_G	147_I	0.687	0.96
641_I	662_L	0.687	0.96
224_T	230_H	0.685	0.96
59_Q	205_K	0.683	0.96
212_Y	295_K	0.682	0.96
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212_Y	302_K	0.682	0.96
382_A	387_I	0.681	0.96
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539_Y	543_R	0.680	0.96
637_A	642_E	0.680	0.96
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428_A	682_N	0.678	0.96
249_I	333_I	0.677	0.96
296_A	299_K	0.677	0.96
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263_R	567_S	0.673	0.96
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322_A	325_K	0.671	0.96
568_F	575_A	0.669	0.96
161_A	165_T	0.668	0.96
589_E	592_T	0.668	0.96
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220_E	230_H	0.668	0.96
99_L	497_I	0.667	0.96
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130_E	133_L	0.666	0.96
554_E	557_H	0.663	0.96
74_L	488_P	0.663	0.96
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532_A	535_S	0.662	0.96
162_A	328_L	0.662	0.96
248_I	301_A	0.661	0.96
691_L	696_K	0.660	0.96
243_N	326_G	0.660	0.96
160_T	321_T	0.659	0.96
362_K	365_Q	0.658	0.95
310_T	344_Y	0.657	0.95
297_A	301_A	0.656	0.95
400_Y	403_M	0.656	0.95
107_T	505_L	0.656	0.95
61_R	201_P	0.654	0.95
121_Y	124_A	0.654	0.95
206_A	209_N	0.653	0.95
194_E	222_A	0.653	0.95
589_E	704_A	0.652	0.95
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589_E	652_P	0.651	0.95
554_E	558_P	0.650	0.95
74_L	485_R	0.650	0.95
653_R	704_A	0.650	0.95
251_D	271_K	0.649	0.95
688_G	703_C	0.648	0.95
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181_H	341_Y	0.646	0.95
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384_V	526_A	0.643	0.95
641_I	645_V	0.642	0.95
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232_K	235_P	0.642	0.95
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113_H	117_A	0.642	0.95
414_L	441_F	0.641	0.95
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246_V	329_N	0.639	0.95
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445_D	449_S	0.637	0.95
569_A	572_D	0.636	0.95
628_F	674_P	0.636	0.95
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555_S	558_P	0.634	0.94
553_P	556_D	0.634	0.94
517_E	524_R	0.634	0.94
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521_N	539_Y	0.633	0.94
205_K	209_N	0.633	0.94
382_A	385_W	0.632	0.94
133_L	513_Y	0.631	0.94
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531_I	537_I	0.630	0.94
88_G	91_M	0.629	0.94
187_L	192_I	0.629	0.94
300_F	330_M	0.628	0.94
109_I	113_H	0.627	0.94
165_T	329_N	0.627	0.94
585_P	588_K	0.625	0.94
575_A	579_V	0.625	0.94
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521_N	538_S	0.624	0.94
188_A	327_F	0.624	0.94
256_N	259_F	0.622	0.94
378_R	382_A	0.621	0.94
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653_R	688_G	0.620	0.94
179_I	309_F	0.620	0.94
244_G	247_K	0.619	0.94
398_S	405_K	0.618	0.94
549_H	552_C	0.618	0.94
595_Y	652_P	0.618	0.94
633_P	663_S	0.618	0.94
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415_F	442_V	0.614	0.93
297_A	330_M	0.613	0.93
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261_Q	268_E	0.613	0.93
572_D	579_V	0.612	0.93
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241_L	288_V	0.611	0.93
52_G	55_N	0.611	0.93
183_R	306_G	0.611	0.93
186_I	306_G	0.611	0.93
586_V	592_T	0.610	0.93
435_L	441_F	0.610	0.93
39_E	46_K	0.609	0.93
50_A	53_I	0.609	0.93
158_A	324_V	0.609	0.93
83_L	90_F	0.608	0.93
180_P	209_N	0.606	0.93
244_G	297_A	0.606	0.93
406_I	437_R	0.604	0.93
155_M	159_A	0.604	0.93
33_C	63_C	0.603	0.93
519_I	524_R	0.602	0.93
318_T	690_A	0.602	0.93
632_H	667_R	0.602	0.93
604_V	628_F	0.602	0.93
259_F	263_R	0.601	0.93
604_V	624_H	0.601	0.93
416_L	421_P	0.601	0.93
175_P	549_H	0.600	0.93
166_F	344_Y	0.600	0.93
564_F	567_S	0.600	0.93
110_Q	113_H	0.600	0.93
69_A	464_Y	0.600	0.93
137_F	140_V	0.599	0.93
64_I	605_M	0.598	0.93
692_D	695_C	0.597	0.93
182_T	307_M	0.597	0.93
240_A	282_I	0.597	0.93
321_T	692_D	0.596	0.92
102_I	415_F	0.595	0.92
321_T	694_A	0.595	0.92
232_K	292_D	0.594	0.92
542_L	545_E	0.594	0.92
572_D	575_A	0.594	0.92
106_V	118_M	0.594	0.92
323_A	327_F	0.593	0.92
113_H	439_T	0.593	0.92
190_T	347_I	0.592	0.92
109_I	118_M	0.592	0.92
552_C	555_S	0.591	0.92
194_E	605_M	0.591	0.92
219_R	672_F	0.591	0.92
687_I	703_C	0.591	0.92
81_R	93_V	0.590	0.92
90_F	93_V	0.589	0.92
182_T	305_S	0.589	0.92
259_F	264_T	0.587	0.92
46_K	70_H	0.587	0.92
244_G	283_A	0.586	0.92
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379_A	385_W	0.586	0.92
24_T	35_M	0.585	0.92
553_P	558_P	0.585	0.92
247_K	276_S	0.585	0.92
531_I	536_G	0.584	0.92
247_K	282_I	0.583	0.92
589_E	653_R	0.583	0.92
191_N	217_D	0.582	0.92
331_V	344_Y	0.582	0.92
509_R	512_S	0.581	0.92
332_L	577_L	0.580	0.91
655_S	708_I	0.580	0.91
300_F	331_V	0.580	0.91
405_K	411_I	0.580	0.91
666_I	672_F	0.579	0.91
86_K	90_F	0.579	0.91
240_A	281_D	0.579	0.91
570_H	573_Q	0.579	0.91
586_V	589_E	0.579	0.91
22_Y	482_E	0.579	0.91
399_A	406_I	0.579	0.91
539_Y	542_L	0.579	0.91
82_P	497_I	0.578	0.91
646_L	660_S	0.577	0.91
360_G	363_A	0.576	0.91
267_F	577_L	0.576	0.91
314_I	324_V	0.576	0.91
304_T	339_K	0.575	0.91
194_E	219_R	0.575	0.91
649_I	707_I	0.575	0.91
235_P	600_T	0.574	0.91
246_V	326_G	0.574	0.91
495_W	499_C	0.574	0.91
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201_P	205_K	0.572	0.91
24_T	481_R	0.571	0.91
396_G	399_A	0.570	0.91
645_V	660_S	0.570	0.91
39_E	47_K	0.569	0.91
515_S	519_I	0.569	0.91
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120_V	134_L	0.569	0.91
598_Y	702_V	0.568	0.91
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571_P	575_A	0.568	0.91
618_A	621_A	0.568	0.91
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127_T	130_E	0.565	0.90
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221_T	224_T	0.564	0.90
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441_F	451_T	0.563	0.90
406_I	409_G	0.563	0.90
466_E	491_A	0.561	0.90
55_N	479_T	0.561	0.90
237_T	240_A	0.561	0.90
40_Q	44_T	0.560	0.90
348_T	352_N	0.560	0.90
401_E	696_K	0.559	0.90
204_E	226_I	0.559	0.90
157_A	697_M	0.558	0.90
91_M	101_H	0.558	0.90
190_T	311_A	0.558	0.90
450_E	453_K	0.557	0.90
112_E	412_K	0.556	0.90
63_C	66_G	0.556	0.90
535_S	538_S	0.555	0.90
552_C	557_H	0.555	0.90
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539_Y	545_E	0.554	0.89
394_R	397_V	0.554	0.89
186_I	330_M	0.554	0.89
446_L	461_A	0.554	0.89
507_K	513_Y	0.553	0.89
84_L	455_A	0.553	0.89
134_L	498_I	0.552	0.89
395_K	402_M	0.551	0.89
516_A	520_F	0.551	0.89
135_G	139_R	0.550	0.89
443_A	451_T	0.549	0.89
293_I	297_A	0.547	0.89
155_M	158_A	0.547	0.89
174_N	307_M	0.547	0.89
596_P	639_Y	0.547	0.89
191_N	194_E	0.547	0.89
522_E	525_E	0.546	0.89
603_R	675_I	0.546	0.89
203_F	213_F	0.546	0.89
73_A	465_L	0.546	0.89
142_L	505_L	0.546	0.89
575_A	578_S	0.546	0.89
39_E	44_T	0.544	0.89
70_H	74_L	0.544	0.89
618_A	622_A	0.544	0.89
249_I	254_L	0.542	0.88
597_L	632_H	0.542	0.88
35_M	51_I	0.542	0.88
217_D	224_T	0.542	0.88
521_N	537_I	0.541	0.88
114_G	412_K	0.541	0.88
305_S	336_K	0.540	0.88
415_F	498_I	0.540	0.88
148_D	152_R	0.540	0.88
632_H	639_Y	0.539	0.88
33_C	66_G	0.539	0.88
517_E	520_F	0.538	0.88
487_C	491_A	0.538	0.88
374_N	378_R	0.538	0.88
179_I	203_F	0.538	0.88
245_L	298_V	0.537	0.88
138_A	147_I	0.537	0.88
39_E	45_R	0.536	0.88
79_I	448_I	0.536	0.88
321_T	695_C	0.536	0.88
296_A	300_F	0.534	0.88
432_K	454_Y	0.534	0.88
545_E	548_I	0.534	0.88
271_K	274_T	0.533	0.88
218_P	600_T	0.533	0.88
188_A	330_M	0.533	0.88
71_Q	617_S	0.533	0.88
289_S	294_R	0.532	0.88
461_A	494_D	0.532	0.88
234_K	598_Y	0.532	0.88
426_P	700_F	0.532	0.88
413_G	438_L	0.531	0.87
106_V	501_L	0.531	0.87
102_I	106_V	0.531	0.87
627_S	674_P	0.530	0.87
138_A	142_L	0.530	0.87
398_S	402_M	0.530	0.87
252_E	279_L	0.530	0.87
142_L	507_K	0.530	0.87
318_T	693_P	0.529	0.87
26_C	63_C	0.528	0.87
249_I	300_F	0.528	0.87
635_T	662_L	0.528	0.87
249_I	306_G	0.527	0.87
112_E	439_T	0.527	0.87
130_E	467_D	0.527	0.87
110_Q	117_A	0.527	0.87
641_I	707_I	0.527	0.87
585_P	589_E	0.527	0.87
219_R	602_G	0.526	0.87
424_S	610_T	0.526	0.87
400_Y	406_I	0.526	0.87
428_A	432_K	0.525	0.87
317_Q	702_V	0.525	0.87
192_I	223_T	0.525	0.87
377_H	381_I	0.524	0.87
217_D	223_T	0.524	0.87
215_A	223_T	0.523	0.87
126_I	130_E	0.523	0.87
245_L	248_I	0.522	0.87
400_Y	404_E	0.522	0.87
292_D	296_A	0.522	0.87
397_V	406_I	0.521	0.86
186_I	300_F	0.521	0.86
402_M	414_L	0.521	0.86
619_A	622_A	0.520	0.86
54_D	59_Q	0.519	0.86
662_L	665_Q	0.519	0.86
416_L	435_L	0.519	0.86
204_E	208_E	0.518	0.86
166_F	337_I	0.518	0.86
71_Q	618_A	0.517	0.86
303_E	339_K	0.517	0.86
234_K	284_E	0.517	0.86
246_V	250_I	0.517	0.86
397_V	404_E	0.516	0.86
542_L	546_G	0.515	0.86
523_L	526_A	0.514	0.86
404_E	689_E	0.514	0.86
395_K	400_Y	0.514	0.86
533_D	537_I	0.514	0.86
638_T	669_D	0.513	0.86
202_Y	205_K	0.513	0.86
635_T	639_Y	0.512	0.86
397_V	400_Y	0.512	0.86
276_S	581_P	0.511	0.85
192_I	347_I	0.511	0.85
404_E	407_N	0.511	0.85
632_H	635_T	0.510	0.85
378_R	393_P	0.510	0.85
443_A	449_S	0.510	0.85
330_M	334_T	0.509	0.85
396_G	400_Y	0.509	0.85
414_L	421_P	0.508	0.85
398_S	403_M	0.508	0.85
278_D	283_A	0.507	0.85
421_P	451_T	0.507	0.85
521_N	543_R	0.507	0.85
288_V	296_A	0.505	0.85
386_G	389_Q	0.505	0.85
237_T	282_I	0.505	0.85
357_R	361_Q	0.504	0.85
187_L	215_A	0.504	0.85
442_V	457_V	0.504	0.85
596_P	652_P	0.504	0.85
300_F	336_K	0.503	0.85
520_F	527_S	0.503	0.85
320_G	324_V	0.503	0.85
217_D	230_H	0.503	0.85
250_I	253_Q	0.502	0.84
255_I	271_K	0.502	0.84
103_K	500_D	0.502	0.84
599_L	671_V	0.502	0.84
49_T	69_A	0.502	0.84
382_A	386_G	0.502	0.84
264_T	267_F	0.502	0.84
414_L	435_L	0.502	0.84
519_I	522_E	0.501	0.84
152_R	156_S	0.501	0.84
146_Y	397_V	0.501	0.84
156_S	697_M	0.500	0.84

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2iv2X	1	0.9282	100	0.165	Contact Map
2napA	1	0.9676	100	0.168	Contact Map
1h0hA	1	0.9803	100	0.178	Contact Map
3ml1A	1	0.9775	100	0.184	Contact Map
1kqfA	3	0.9775	100	0.189	Contact Map
2e7zA	1	0.9324	100	0.19	Contact Map
2vpzA	1	0.9451	100	0.201	Contact Map
2ivfA	1	0.9732	100	0.211	Contact Map
1q16A	2	0.9901	100	0.215	Contact Map
4aayA	6	0.9338	100	0.229	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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