LON2 - BACSU - GREMLIN Contacts

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LON2 - Lon protease 2

UniProt:	P42425	Sequences: MSWTGIALFIQLFFGIIIGLYFWNLLKNQRTQKVTIDKESKKEMEQLRKMRAISLSEPLSEKVRPKSFKDIVGQEDGIKALKAALCGPNPQHVIVYGPPGVGKTAAARLVLEEAKKHKQSPFKEQAVFVELDATTARFDERGIADPLIGSVHDPIYQGAGAMGQAGIPQPKQGAVTHAHGGVLFIDEIGELHPIQMNKMLKVLEDRKVFLDSAYYSEENTQIPNHIHDIFQNGLPADFRLIGATTRMPNEIPPAIRSRCLEVFFRELEKDELKTVAKTAADKIEKNISEEGLDLLTSYTRNGREAVNMIQIAAGMAVTENRKDITIEDIEWVIHSSQLTPKHEQKIGVEPQVGIVNGLAVYGPNSGSLLEIEVSVTAAQDKGSINITGIAEEESIGSQSKSIRRKSMAKGSVENVLTVLRTMGMKPSDYDIHINFPGGIPIDGPSAGIAMAAGIFSAIHKIPIDNTVAMTGEISLNGLVKPIGGVIPKIKAAKQSGAKKVIIPYENQQAILKQIDGIEIIAVKTFQEVLDEILVNPPTEQKPFHIEINKESV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	552 (480)
Sequences:	3926 (2047)
Seq/√Len:	93.4

ECOLI - LON LONH
BACSU - LON2 LON1
HALSA - LONB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
504_Y	523_K	5.549	1.00
482_I	485_V	5.535	1.00
504_Y	507_Q	4.508	1.00
56_S	60_S	3.998	1.00
61_E	112_E	3.799	1.00
46_Q	167_I	3.643	1.00
277_K	289_E	3.619	1.00
499_K	520_I	3.588	1.00
158_G	183_L	3.227	1.00
373_V	453_G	3.212	1.00
274_T	278_T	3.169	1.00
522_V	527_E	3.037	1.00
499_K	518_E	3.027	1.00
520_I	531_E	2.911	1.00
489_I	519_I	2.819	1.00
448_I	528_V	2.725	1.00
375_V	457_A	2.680	1.00
81_L	313_A	2.665	1.00
325_T	328_D	2.665	1.00
288_S	291_G	2.664	1.00
502_I	521_A	2.661	1.00
45_E	168_P	2.660	1.00
493_K	516_G	2.649	1.00
156_Y	234_L	2.600	1.00
468_A	497_A	2.595	1.00
10_I	37_D	2.590	1.00
466_T	498_K	2.510	1.00
45_E	238_F	2.507	1.00
281_D	287_I	2.495	1.00
397_S	400_K	2.420	1.00
7_A	11_Q	2.377	1.00
168_P	234_L	2.371	1.00
499_K	531_E	2.354	1.00
522_V	528_V	2.339	1.00
501_I	531_E	2.286	1.00
452_A	528_V	2.272	1.00
191_L	199_M	2.266	1.00
507_Q	521_A	2.185	1.00
527_E	530_D	2.177	1.00
386_I	403_R	2.168	1.00
510_I	521_A	2.146	1.00
293_D	297_S	2.096	1.00
501_I	522_V	2.071	1.00
485_V	502_I	2.068	1.00
315_M	331_W	2.041	1.00
424_M	428_D	2.024	1.00
523_K	527_E	2.019	1.00
256_R	261_E	1.996	1.00
56_S	318_T	1.992	1.00
37_D	222_I	1.983	1.00
451_A	525_F	1.973	1.00
40_S	234_L	1.969	1.00
451_A	473_I	1.937	1.00
452_A	532_I	1.889	1.00
448_I	479_V	1.885	1.00
415_V	418_V	1.879	1.00
54_S	57_E	1.866	1.00
352_V	460_K	1.860	1.00
49_K	54_S	1.858	1.00
269_K	296_T	1.854	1.00
46_Q	125_Q	1.846	1.00
415_V	526_Q	1.818	1.00
382_G	430_D	1.780	1.00
461_I	533_L	1.773	1.00
140_E	202_V	1.770	1.00
162_M	234_L	1.756	1.00
455_F	529_L	1.756	1.00
489_I	500_V	1.755	1.00
467_V	499_K	1.743	1.00
274_T	277_K	1.692	1.00
371_I	449_A	1.692	1.00
502_I	510_I	1.683	1.00
482_I	502_I	1.679	1.00
297_S	336_S	1.672	1.00
54_S	58_P	1.667	1.00
308_M	324_I	1.665	1.00
464_D	499_K	1.662	1.00
312_A	316_A	1.662	1.00
400_K	406_S	1.661	1.00
314_G	318_T	1.652	1.00
501_I	528_V	1.652	1.00
253_P	256_R	1.650	1.00
290_E	326_I	1.641	1.00
127_V	183_L	1.622	1.00
281_D	305_A	1.617	1.00
350_P	534_V	1.609	1.00
288_S	325_T	1.605	1.00
489_I	502_I	1.603	1.00
306_V	310_Q	1.596	1.00
452_A	463_I	1.594	1.00
20_L	28_N	1.588	1.00
168_P	238_F	1.575	1.00
293_D	326_I	1.575	1.00
368_L	495_S	1.571	1.00
126_A	130_E	1.561	1.00
381_K	427_S	1.561	1.00
359_A	369_L	1.559	1.00
328_D	332_V	1.553	1.00
107_A	184_F	1.550	1.00
53_I	318_T	1.530	1.00
284_E	306_V	1.528	1.00
126_A	132_D	1.526	1.00
350_P	465_N	1.525	1.00
10_I	14_F	1.519	1.00
127_V	165_A	1.516	1.00
57_E	61_E	1.514	1.00
16_I	32_Q	1.506	1.00
248_P	261_E	1.497	1.00
125_Q	167_I	1.492	1.00
373_V	457_A	1.483	1.00
8_L	166_G	1.475	1.00
448_I	522_V	1.474	1.00
85_L	88_P	1.462	1.00
339_T	505_E	1.448	1.00
385_N	406_S	1.441	1.00
128_F	131_L	1.436	0.99
435_F	450_M	1.432	0.99
131_L	185_I	1.429	0.99
310_Q	314_G	1.426	0.99
291_G	329_I	1.425	0.99
355_V	463_I	1.423	0.99
482_I	489_I	1.421	0.99
248_P	256_R	1.420	0.99
44_M	47_L	1.420	0.99
95_V	110_V	1.413	0.99
10_I	34_V	1.405	0.99
529_L	533_L	1.403	0.99
489_I	517_I	1.402	0.99
411_S	525_F	1.385	0.99
43_E	168_P	1.377	0.99
130_E	133_A	1.371	0.99
11_Q	14_F	1.362	0.99
187_E	190_E	1.361	0.99
73_G	314_G	1.360	0.99
376_T	410_G	1.344	0.99
287_I	329_I	1.340	0.99
461_I	535_N	1.338	0.99
431_I	458_I	1.337	0.99
287_I	308_M	1.327	0.99
294_L	308_M	1.310	0.99
485_V	489_I	1.307	0.99
358_L	500_V	1.297	0.99
355_V	449_A	1.294	0.99
389_I	397_S	1.294	0.99
247_M	250_E	1.292	0.99
281_D	292_L	1.276	0.99
449_A	528_V	1.267	0.99
315_M	332_V	1.259	0.99
128_F	132_D	1.255	0.99
362_G	365_S	1.255	0.99
452_A	469_M	1.254	0.99
20_L	30_R	1.252	0.99
212_S	233_G	1.246	0.99
135_T	218_E	1.240	0.99
485_V	521_A	1.238	0.98
125_Q	131_L	1.238	0.98
361_Y	364_N	1.238	0.98
127_V	131_L	1.235	0.98
127_V	130_E	1.233	0.98
304_E	307_N	1.227	0.98
126_A	184_F	1.223	0.98
145_D	221_Q	1.217	0.98
426_P	458_I	1.207	0.98
128_F	133_A	1.203	0.98
125_Q	130_E	1.202	0.98
361_Y	365_S	1.198	0.98
293_D	336_S	1.195	0.98
343_E	367_S	1.188	0.98
375_V	429_Y	1.183	0.98
14_F	38_K	1.176	0.98
55_L	58_P	1.175	0.98
416_L	421_T	1.172	0.98
162_M	168_P	1.169	0.98
36_I	157_Q	1.167	0.98
20_L	27_K	1.167	0.98
315_M	320_N	1.160	0.98
467_V	531_E	1.160	0.98
56_S	314_G	1.157	0.98
528_V	532_I	1.155	0.98
502_I	519_I	1.150	0.98
125_Q	166_G	1.146	0.97
411_S	415_V	1.144	0.97
126_A	131_L	1.144	0.97
135_T	138_F	1.138	0.97
273_K	289_E	1.136	0.97
431_I	454_I	1.135	0.97
386_I	400_K	1.131	0.97
13_F	23_W	1.131	0.97
409_K	431_I	1.129	0.97
124_E	131_L	1.125	0.97
321_R	328_D	1.121	0.97
467_V	520_I	1.111	0.97
356_N	368_L	1.111	0.97
294_L	333_I	1.107	0.97
355_V	453_G	1.097	0.97
275_V	280_A	1.097	0.97
124_E	130_E	1.096	0.97
412_V	455_F	1.091	0.97
351_Q	478_L	1.087	0.97
106_A	264_F	1.086	0.97
293_D	329_I	1.085	0.97
291_G	326_I	1.074	0.96
258_R	262_V	1.065	0.96
58_P	112_E	1.062	0.96
35_T	39_E	1.060	0.96
67_S	307_N	1.058	0.96
108_R	112_E	1.057	0.96
68_F	95_V	1.057	0.96
467_V	532_I	1.052	0.96
390_A	435_F	1.052	0.96
9_F	13_F	1.050	0.96
127_V	133_A	1.048	0.96
70_D	311_I	1.046	0.96
277_K	292_L	1.043	0.96
9_F	23_W	1.039	0.96
127_V	158_G	1.039	0.96
124_E	133_A	1.037	0.95
126_A	133_A	1.035	0.95
129_V	158_G	1.035	0.95
56_S	73_G	1.034	0.95
110_V	242_G	1.033	0.95
188_I	199_M	1.028	0.95
448_I	469_M	1.026	0.95
129_V	132_D	1.018	0.95
376_T	413_E	1.009	0.95
12_L	39_E	1.008	0.95
305_A	310_Q	1.005	0.95
252_P	262_V	1.004	0.95
481_P	505_E	1.002	0.95
212_S	221_Q	1.002	0.95
51_R	54_S	0.997	0.94
330_E	511_L	0.992	0.94
448_I	452_A	0.990	0.94
522_V	531_E	0.990	0.94
27_K	30_R	0.988	0.94
415_V	419_L	0.983	0.94
358_L	468_A	0.981	0.94
296_T	344_Q	0.978	0.94
258_R	264_F	0.971	0.94
125_Q	128_F	0.971	0.94
349_E	352_V	0.966	0.93
416_L	420_R	0.966	0.93
255_I	258_R	0.966	0.93
81_L	316_A	0.962	0.93
9_F	12_L	0.962	0.93
125_Q	133_A	0.960	0.93
70_D	314_G	0.958	0.93
34_V	38_K	0.957	0.93
375_V	458_I	0.956	0.93
500_V	517_I	0.955	0.93
46_Q	50_M	0.953	0.93
425_K	458_I	0.952	0.93
354_I	370_E	0.951	0.93
380_D	430_D	0.951	0.93
36_I	163_G	0.950	0.93
23_W	27_K	0.950	0.93
276_A	280_A	0.948	0.93
127_V	132_D	0.947	0.93
418_V	526_Q	0.947	0.93
479_V	528_V	0.943	0.93
125_Q	132_D	0.942	0.93
498_K	516_G	0.942	0.93
55_L	76_D	0.941	0.92
149_G	158_G	0.935	0.92
313_A	317_V	0.935	0.92
335_S	511_L	0.933	0.92
474_S	478_L	0.933	0.92
21_Y	27_K	0.932	0.92
275_V	284_E	0.931	0.92
510_I	513_Q	0.930	0.92
68_F	264_F	0.929	0.92
124_E	128_F	0.929	0.92
356_N	370_E	0.927	0.92
25_L	148_I	0.926	0.92
268_E	486_I	0.925	0.92
525_F	529_L	0.923	0.92
256_R	263_F	0.923	0.92
124_E	127_V	0.920	0.92
311_I	332_V	0.919	0.92
20_L	25_L	0.915	0.91
507_Q	511_L	0.912	0.91
6_I	10_I	0.906	0.91
352_V	462_P	0.906	0.91
324_I	329_I	0.903	0.91
124_E	132_D	0.902	0.91
524_T	527_E	0.902	0.91
50_M	80_A	0.897	0.91
273_K	276_A	0.897	0.91
40_S	156_Y	0.896	0.91
147_L	151_V	0.895	0.90
252_P	255_I	0.894	0.90
309_I	313_A	0.892	0.90
52_A	77_G	0.890	0.90
473_I	525_F	0.890	0.90
304_E	337_Q	0.889	0.90
474_S	480_K	0.886	0.90
419_L	455_F	0.886	0.90
461_I	534_V	0.884	0.90
303_R	310_Q	0.883	0.90
464_D	532_I	0.882	0.90
146_P	149_G	0.881	0.90
13_F	21_Y	0.881	0.90
510_I	519_I	0.880	0.90
312_A	332_V	0.879	0.90
449_A	491_A	0.876	0.90
276_A	284_E	0.872	0.89
316_A	319_E	0.872	0.89
252_P	258_R	0.870	0.89
383_S	430_D	0.867	0.89
489_I	493_K	0.866	0.89
284_E	305_A	0.865	0.89
328_D	331_W	0.864	0.89
150_S	153_D	0.864	0.89
389_I	396_G	0.864	0.89
282_K	286_N	0.861	0.89
261_E	264_F	0.860	0.89
280_A	284_E	0.858	0.89
448_I	525_F	0.856	0.88
359_A	362_G	0.855	0.88
478_L	523_K	0.853	0.88
448_I	451_A	0.851	0.88
31_T	35_T	0.850	0.88
346_I	495_S	0.850	0.88
260_L	264_F	0.849	0.88
9_F	221_Q	0.849	0.88
55_L	73_G	0.845	0.88
469_M	528_V	0.843	0.88
306_V	309_I	0.830	0.87
98_P	103_K	0.829	0.87
58_P	61_E	0.826	0.87
407_M	442_D	0.826	0.87
258_R	267_L	0.822	0.86
162_M	239_R	0.821	0.86
202_V	236_A	0.819	0.86
96_Y	256_R	0.817	0.86
158_G	164_Q	0.814	0.86
506_N	509_A	0.814	0.86
403_R	433_I	0.813	0.86
288_S	327_E	0.811	0.86
53_I	57_E	0.808	0.85
250_E	256_R	0.805	0.85
10_I	38_K	0.804	0.85
287_I	312_A	0.802	0.85
274_T	286_N	0.802	0.85
352_V	459_H	0.797	0.85
196_M	252_P	0.796	0.85
162_M	165_A	0.796	0.85
263_F	266_E	0.795	0.84
15_G	18_I	0.795	0.84
489_I	521_A	0.795	0.84
525_F	528_V	0.794	0.84
35_T	38_K	0.791	0.84
128_F	259_C	0.791	0.84
312_A	317_V	0.789	0.84
126_A	182_V	0.789	0.84
188_I	191_L	0.787	0.84
252_P	260_L	0.786	0.84
167_I	170_P	0.785	0.84
290_E	515_D	0.784	0.84
9_F	21_Y	0.782	0.83
50_M	54_S	0.781	0.83
275_V	283_I	0.781	0.83
43_E	234_L	0.780	0.83
307_N	310_Q	0.778	0.83
17_I	27_K	0.778	0.83
293_D	330_E	0.771	0.83
129_V	133_A	0.771	0.83
25_L	29_Q	0.770	0.83
374_S	410_G	0.769	0.82
449_A	452_A	0.769	0.82
251_I	255_I	0.768	0.82
103_K	243_A	0.767	0.82
383_S	406_S	0.767	0.82
96_Y	247_M	0.766	0.82
433_I	450_M	0.764	0.82
273_K	277_K	0.762	0.82
252_P	256_R	0.762	0.82
143_I	146_P	0.761	0.82
96_Y	250_E	0.760	0.82
504_Y	527_E	0.757	0.81
16_I	36_I	0.756	0.81
48_R	114_A	0.754	0.81
12_L	163_G	0.754	0.81
186_D	189_G	0.752	0.81
40_S	220_T	0.752	0.81
63_V	274_T	0.752	0.81
359_A	491_A	0.749	0.81
464_D	534_V	0.747	0.81
156_Y	162_M	0.745	0.80
206_R	237_D	0.745	0.80
284_E	309_I	0.742	0.80
367_S	371_I	0.741	0.80
256_R	262_V	0.740	0.80
146_P	152_H	0.739	0.80
147_L	153_D	0.739	0.80
455_F	533_L	0.739	0.80
258_R	268_E	0.735	0.80
279_A	284_E	0.733	0.79
114_A	240_L	0.733	0.79
75_E	79_K	0.731	0.79
6_I	14_F	0.731	0.79
95_V	107_A	0.730	0.79
147_L	158_G	0.724	0.78
262_V	266_E	0.723	0.78
158_G	165_A	0.722	0.78
384_I	403_R	0.722	0.78
36_I	220_T	0.721	0.78
347_G	476_N	0.720	0.78
149_G	165_A	0.719	0.78
433_I	454_I	0.718	0.78
37_D	40_S	0.717	0.78
11_Q	15_G	0.716	0.78
127_V	134_T	0.714	0.78
7_A	38_K	0.713	0.77
521_A	527_E	0.712	0.77
74_Q	314_G	0.712	0.77
38_K	222_I	0.712	0.77
426_P	429_Y	0.711	0.77
27_K	31_T	0.711	0.77
131_L	141_R	0.711	0.77
449_A	469_M	0.711	0.77
25_L	28_N	0.710	0.77
279_A	283_I	0.709	0.77
6_I	37_D	0.707	0.77
260_L	267_L	0.707	0.77
20_L	24_N	0.706	0.77
354_I	478_L	0.701	0.76
53_I	56_S	0.699	0.76
413_E	426_P	0.696	0.76
149_G	153_D	0.696	0.76
247_M	256_R	0.693	0.75
146_P	170_P	0.692	0.75
252_P	266_E	0.692	0.75
258_R	266_E	0.691	0.75
452_A	533_L	0.691	0.75
452_A	529_L	0.691	0.75
357_G	371_I	0.690	0.75
24_N	36_I	0.690	0.75
262_V	268_E	0.688	0.75
104_T	111_L	0.688	0.75
217_E	220_T	0.687	0.75
313_A	316_A	0.687	0.75
8_L	18_I	0.685	0.75
153_D	170_P	0.684	0.74
264_F	267_L	0.682	0.74
507_Q	510_I	0.681	0.74
510_I	514_I	0.680	0.74
498_K	518_E	0.680	0.74
256_R	266_E	0.679	0.74
165_A	170_P	0.678	0.74
502_I	507_Q	0.676	0.74
191_L	196_M	0.675	0.74
455_F	525_F	0.674	0.73
258_R	263_F	0.672	0.73
111_L	114_A	0.670	0.73
48_R	169_Q	0.670	0.73
489_I	510_I	0.669	0.73
379_Q	429_Y	0.669	0.73
9_F	370_E	0.667	0.73
252_P	264_F	0.665	0.72
129_V	183_L	0.664	0.72
275_V	286_N	0.663	0.72
361_Y	491_A	0.660	0.72
6_I	222_I	0.660	0.72
413_E	425_K	0.660	0.72
348_V	465_N	0.659	0.72
147_L	152_H	0.659	0.72
21_Y	25_L	0.658	0.72
351_Q	476_N	0.658	0.72
358_L	368_L	0.658	0.72
145_D	153_D	0.657	0.71
66_K	70_D	0.657	0.71
421_T	459_H	0.655	0.71
48_R	79_K	0.655	0.71
429_Y	458_I	0.654	0.71
191_L	252_P	0.654	0.71
500_V	520_I	0.653	0.71
8_L	11_Q	0.652	0.71
83_A	87_G	0.652	0.71
303_R	314_G	0.651	0.71
322_K	327_E	0.649	0.71
273_K	295_L	0.646	0.70
188_I	243_A	0.645	0.70
47_L	83_A	0.645	0.70
22_F	25_L	0.645	0.70
33_K	37_D	0.644	0.70
146_P	150_S	0.644	0.70
384_I	409_K	0.644	0.70
470_T	483_G	0.643	0.70
296_T	343_E	0.640	0.70
146_P	158_G	0.640	0.70
371_I	435_F	0.639	0.69
13_F	33_K	0.638	0.69
248_P	263_F	0.637	0.69
262_V	265_R	0.637	0.69
84_A	238_F	0.636	0.69
151_V	170_P	0.636	0.69
26_L	30_R	0.634	0.69
38_K	43_E	0.633	0.69
386_I	409_K	0.631	0.68
13_F	32_Q	0.631	0.68
26_L	35_T	0.631	0.68
36_I	40_S	0.631	0.68
276_A	292_L	0.630	0.68
294_L	332_V	0.630	0.68
47_L	51_R	0.629	0.68
252_P	263_F	0.627	0.68
417_T	422_M	0.627	0.68
21_Y	39_E	0.626	0.68
73_G	76_D	0.625	0.68
451_A	455_F	0.625	0.68
107_A	126_A	0.624	0.68
486_I	490_K	0.624	0.68
403_R	449_A	0.623	0.67
331_W	515_D	0.623	0.67
255_I	262_V	0.622	0.67
412_V	454_I	0.622	0.67
108_R	206_R	0.622	0.67
43_E	47_L	0.621	0.67
466_T	497_A	0.621	0.67
285_K	309_I	0.621	0.67
28_N	32_Q	0.619	0.67
258_R	272_L	0.619	0.67
149_G	170_P	0.618	0.67
134_T	218_E	0.618	0.67
79_K	85_L	0.617	0.67
482_I	521_A	0.617	0.67
278_T	282_K	0.617	0.67
291_G	324_I	0.615	0.66
109_L	112_E	0.615	0.66
30_R	37_D	0.614	0.66
147_L	170_P	0.614	0.66
463_I	533_L	0.611	0.66
53_I	320_N	0.611	0.66
147_L	155_I	0.610	0.66
15_G	22_F	0.609	0.66
362_G	399_S	0.609	0.66
153_D	163_G	0.609	0.66
56_S	66_K	0.607	0.65
315_M	321_R	0.607	0.65
36_I	156_Y	0.606	0.65
478_L	524_T	0.605	0.65
106_A	157_Q	0.605	0.65
411_S	414_N	0.604	0.65
280_A	294_L	0.604	0.65
6_I	12_L	0.603	0.65
482_I	506_N	0.602	0.65
348_V	462_P	0.599	0.64
146_P	153_D	0.599	0.64
330_E	334_H	0.599	0.64
274_T	284_E	0.599	0.64
48_R	125_Q	0.598	0.64
34_V	79_K	0.598	0.64
147_L	169_Q	0.598	0.64
24_N	29_Q	0.597	0.64
32_Q	36_I	0.597	0.64
11_Q	18_I	0.597	0.64
276_A	283_I	0.596	0.64
275_V	279_A	0.595	0.64
267_L	272_L	0.593	0.64
153_D	169_Q	0.593	0.64
134_T	140_E	0.592	0.64
352_V	465_N	0.592	0.64
260_L	263_F	0.591	0.63
15_G	345_K	0.590	0.63
52_A	60_S	0.590	0.63
416_L	419_L	0.589	0.63
278_T	286_N	0.589	0.63
12_L	16_I	0.589	0.63
30_R	35_T	0.587	0.63
275_V	278_T	0.586	0.63
350_P	466_T	0.586	0.63
294_L	305_A	0.586	0.63
379_Q	428_D	0.586	0.63
246_R	434_N	0.585	0.63
316_A	321_R	0.585	0.63
47_L	50_M	0.584	0.62
10_I	43_E	0.584	0.62
500_V	519_I	0.583	0.62
463_I	466_T	0.583	0.62
140_E	198_K	0.582	0.62
134_T	191_L	0.582	0.62
20_L	23_W	0.582	0.62
150_S	169_Q	0.581	0.62
287_I	291_G	0.580	0.62
22_F	30_R	0.580	0.62
134_T	197_N	0.580	0.62
5_G	18_I	0.579	0.62
354_I	368_L	0.579	0.62
133_A	136_A	0.579	0.62
157_Q	164_Q	0.578	0.62
262_V	272_L	0.577	0.62
495_S	498_K	0.576	0.61
152_H	165_A	0.575	0.61
457_A	476_N	0.574	0.61
22_F	27_K	0.574	0.61
18_I	21_Y	0.573	0.61
262_V	267_L	0.573	0.61
287_I	324_I	0.572	0.61
25_L	39_E	0.571	0.61
154_P	212_S	0.571	0.61
95_V	242_G	0.570	0.61
146_P	165_A	0.568	0.60
165_A	168_P	0.568	0.60
80_A	317_V	0.568	0.60
288_S	328_D	0.567	0.60
287_I	305_A	0.566	0.60
21_Y	24_N	0.566	0.60
8_L	418_V	0.564	0.60
294_L	335_S	0.564	0.60
330_E	336_S	0.564	0.60
356_N	465_N	0.563	0.60
112_E	279_A	0.562	0.60
407_M	410_G	0.561	0.59
293_D	296_T	0.561	0.59
273_K	292_L	0.560	0.59
145_D	150_S	0.557	0.59
112_E	115_K	0.557	0.59
152_H	170_P	0.557	0.59
307_N	314_G	0.557	0.59
366_G	484_G	0.557	0.59
527_E	531_E	0.557	0.59
37_D	43_E	0.556	0.59
252_P	257_S	0.555	0.59
276_A	286_N	0.555	0.59
287_I	292_L	0.554	0.58
442_D	449_A	0.554	0.58
260_L	272_L	0.554	0.58
114_A	182_V	0.554	0.58
13_F	221_Q	0.553	0.58
313_A	324_I	0.553	0.58
15_G	19_G	0.553	0.58
19_G	23_W	0.552	0.58
464_D	497_A	0.552	0.58
166_G	170_P	0.551	0.58
147_L	150_S	0.551	0.58
131_L	134_T	0.550	0.58
15_G	39_E	0.550	0.58
151_V	167_I	0.549	0.58
463_I	532_I	0.549	0.58
35_T	40_S	0.547	0.58
493_K	514_I	0.547	0.58
297_S	343_E	0.546	0.57
81_L	317_V	0.546	0.57
9_F	30_R	0.546	0.57
363_P	442_D	0.546	0.57
13_F	184_F	0.543	0.57
182_V	240_L	0.543	0.57
290_E	331_W	0.542	0.57
9_F	27_K	0.542	0.57
515_D	518_E	0.541	0.57
72_V	106_A	0.541	0.57
73_G	345_K	0.541	0.57
27_K	164_Q	0.540	0.57
249_N	439_I	0.539	0.56
149_G	166_G	0.537	0.56
417_T	423_G	0.537	0.56
49_K	115_K	0.536	0.56
63_V	278_T	0.536	0.56
27_K	184_F	0.534	0.56
254_A	257_S	0.533	0.56
7_A	61_E	0.532	0.55
131_L	136_A	0.532	0.55
40_S	168_P	0.532	0.55
146_P	151_V	0.532	0.55
335_S	508_Q	0.532	0.55
285_K	316_A	0.531	0.55
251_I	258_R	0.530	0.55
396_G	403_R	0.529	0.55
149_G	152_H	0.529	0.55
319_E	328_D	0.528	0.55
145_D	514_I	0.527	0.55
36_I	39_E	0.526	0.55
132_D	136_A	0.525	0.54
96_Y	263_F	0.522	0.54
274_T	279_A	0.522	0.54
288_S	326_I	0.521	0.54
370_E	457_A	0.520	0.54
35_T	72_V	0.519	0.54
145_D	151_V	0.519	0.54
7_A	43_E	0.519	0.54
53_I	515_D	0.519	0.54
10_I	510_I	0.519	0.54
101_V	105_A	0.518	0.53
54_S	61_E	0.518	0.53
335_S	512_K	0.517	0.53
42_K	45_E	0.517	0.53
16_I	35_T	0.517	0.53
416_L	455_F	0.516	0.53
49_K	53_I	0.516	0.53
280_A	286_N	0.516	0.53
57_E	60_S	0.515	0.53
530_D	536_P	0.513	0.53
273_K	278_T	0.513	0.53
255_I	264_F	0.512	0.53
9_F	222_I	0.511	0.53
47_L	57_E	0.511	0.53
403_R	435_F	0.510	0.52
155_I	162_M	0.510	0.52
479_V	522_V	0.510	0.52
281_D	285_K	0.509	0.52
81_L	233_G	0.509	0.52
202_V	243_A	0.509	0.52
312_A	329_I	0.508	0.52
345_K	505_E	0.508	0.52
25_L	192_H	0.507	0.52
359_A	367_S	0.507	0.52
151_V	158_G	0.507	0.52
137_R	141_R	0.506	0.52
19_G	50_M	0.506	0.52
448_I	473_I	0.506	0.52
200_L	258_R	0.505	0.52
346_I	465_N	0.505	0.52
25_L	30_R	0.504	0.52
10_I	36_I	0.503	0.51
429_Y	460_K	0.502	0.51
144_A	147_L	0.502	0.51
47_L	53_I	0.501	0.51
133_A	146_P	0.501	0.51
345_K	370_E	0.500	0.51

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3m6aA	3	0.8279	100	0.506	Contact Map
3k1jA	4	0.8659	100	0.588	Contact Map
4fwgA	3	0.837	100	0.593	Contact Map
3wu4A	3	0.3424	100	0.78	Contact Map
2x36A	3	0.3388	100	0.782	Contact Map
1xhkA	2	0.3261	100	0.79	Contact Map
1z0wA	3	0.3533	100	0.798	Contact Map
1r6bX	1	0.5543	100	0.852	Contact Map
4ciuA	1	0.5272	100	0.854	Contact Map
1g41A	3	0.4348	99.9	0.856	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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