YXDM - BACSU - GREMLIN Contacts

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YXDM - ABC transporter permease protein YxdM

UniProt:	P42424	Sequences: MTFLQFAYKNVTRNKRAYLAFFLSSAFSVLIFFTFAMFLFHPALKEGYLNNIAKKGLTAAEWMIFVFSFLFVLYSVNAFLKSRNKEFGILLMQGITPGQLRKLITAENMIIGVMSIAAGIIGGFIFSKTFFTVGAYILEMDALPLYMPWKALGITACGFLLLFFFLSQFTILFVRSNTVIKLIKGTGKVKPEPKPSVLLSLFGIACLCGGYGMVLKGNVHGAEPFIILLLTVIGTYFFFSQSSIWILRALKKWKTFYLRGKNIIWVSDLVYRLKDNARLFFIVSIISAVAFTATGVLAMYKSTVGAEESAYEMEYLSYSNNPKEQTHLKDIDHELKTHGFTYTKDKIDVSYVRYQEGETVPPVYMISESDAAKYFHVKVNGLKEDEAVYFPGTYDRNFKNEAPDQLKLLNQKGELSDQKLSVKEVKKPLISLNAIIAVNDQTFDQLKSLGDKASLYGYSYDHWKDSLEISQSLQNEIYGNYIDVHSDFASKAGTYYDTVQLPSLSLFIGLFIAIVFFVAAASFLYFRLFTDLDEDRERYRSLAKIGLSEREMAQSVTIQLAILFFFPFVIAVMHTLFALRTLAVEGYSDVAGPLSLTIGGFFIFQLLFFLAVRSSYLKKMNK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	622 (598)
Sequences:	2282 (2001)
Seq/√Len:	81.8

ECOLI - YBBP
BACSU - YXDM YVCS BCEB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
368_E	372_A	6.415	1.00
366_I	369_S	5.609	1.00
367_S	370_D	5.438	1.00
211_Y	214_V	4.677	1.00
382_L	386_E	4.445	1.00
211_Y	215_L	4.275	1.00
369_S	372_A	4.202	1.00
147_M	152_L	4.163	1.00
368_E	371_A	4.148	1.00
206_C	210_G	4.080	1.00
210_G	214_V	3.883	1.00
366_I	371_A	3.881	1.00
369_S	440_D	3.769	1.00
262_N	558_I	3.721	1.00
595_S	599_G	3.677	1.00
153_G	157_C	3.513	1.00
206_C	230_L	3.432	1.00
366_I	370_D	3.401	1.00
586_G	589_D	3.303	1.00
380_N	386_E	3.295	1.00
372_A	375_F	3.214	1.00
372_A	376_H	3.146	1.00
210_G	213_M	3.133	1.00
366_I	372_A	3.068	1.00
367_S	371_A	3.033	1.00
370_D	373_K	2.948	1.00
83_R	107_E	2.917	1.00
249_A	253_W	2.903	1.00
215_L	577_F	2.895	1.00
207_L	211_Y	2.835	1.00
367_S	372_A	2.786	1.00
76_V	170_T	2.651	1.00
382_L	385_D	2.604	1.00
337_T	340_F	2.516	1.00
382_L	387_A	2.461	1.00
362_P	366_I	2.460	1.00
383_K	386_E	2.454	1.00
235_T	574_H	2.425	1.00
33_F	37_M	2.414	1.00
208_C	212_G	2.407	1.00
438_V	442_T	2.357	1.00
335_L	339_G	2.325	1.00
365_M	369_S	2.319	1.00
422_V	425_V	2.282	1.00
211_Y	574_H	2.252	1.00
210_G	234_G	2.246	1.00
439_N	442_T	2.230	1.00
371_A	375_F	2.222	1.00
369_S	376_H	2.203	1.00
280_F	286_I	2.173	1.00
437_A	440_D	2.165	1.00
231_T	578_A	2.159	1.00
26_A	118_A	2.135	1.00
184_K	187_G	2.133	1.00
605_Q	612_V	2.133	1.00
384_E	441_Q	2.124	1.00
212_G	216_K	2.121	1.00
206_C	214_V	2.107	1.00
362_P	367_S	2.102	1.00
574_H	578_A	2.096	1.00
366_I	376_H	2.091	1.00
264_I	268_D	2.091	1.00
172_L	176_S	2.085	1.00
238_F	570_I	2.074	1.00
124_F	147_M	2.050	1.00
385_D	442_T	1.982	1.00
84_N	185_G	1.956	1.00
22_F	115_S	1.955	1.00
205_A	209_G	1.915	1.00
362_P	369_S	1.913	1.00
553_A	617_L	1.903	1.00
129_T	132_T	1.899	1.00
30_L	122_G	1.871	1.00
382_L	388_V	1.851	1.00
569_V	573_M	1.848	1.00
327_H	331_I	1.836	1.00
239_F	284_S	1.821	1.00
540_R	544_K	1.816	1.00
557_T	609_F	1.804	1.00
554_Q	558_I	1.802	1.00
314_E	491_K	1.801	1.00
21_F	108_N	1.780	1.00
288_A	292_T	1.771	1.00
407_K	410_N	1.765	1.00
325_Q	329_K	1.737	1.00
121_I	125_I	1.724	1.00
462_H	465_D	1.712	1.00
364_Y	369_S	1.707	1.00
364_Y	367_S	1.706	1.00
362_P	372_A	1.694	1.00
31_I	34_T	1.694	1.00
196_S	200_S	1.690	1.00
9_K	13_R	1.677	1.00
328_L	334_E	1.669	1.00
207_L	214_V	1.638	1.00
210_G	231_T	1.629	1.00
324_E	327_H	1.625	1.00
371_A	376_H	1.624	1.00
10_N	24_S	1.607	1.00
379_V	382_L	1.606	1.00
384_E	387_A	1.598	1.00
381_G	386_E	1.596	1.00
264_I	547_L	1.594	1.00
380_N	387_A	1.590	1.00
362_P	368_E	1.588	1.00
289_V	293_A	1.588	1.00
490_S	493_G	1.587	1.00
465_D	468_E	1.587	1.00
91_L	100_L	1.584	1.00
406_L	410_N	1.582	1.00
294_T	513_A	1.577	1.00
29_V	32_F	1.576	1.00
89_I	92_M	1.576	1.00
524_L	563_L	1.570	1.00
67_F	71_F	1.553	1.00
572_V	598_I	1.531	0.99
368_E	376_H	1.530	0.99
181_K	188_K	1.530	0.99
29_V	116_I	1.518	0.99
289_V	292_T	1.516	0.99
286_I	290_A	1.510	0.99
32_F	155_T	1.508	0.99
209_G	213_M	1.507	0.99
368_E	382_L	1.505	0.99
328_L	335_L	1.503	0.99
87_F	104_I	1.499	0.99
609_F	613_R	1.493	0.99
203_G	211_Y	1.493	0.99
139_E	499_V	1.485	0.99
471_Q	475_N	1.477	0.99
365_M	370_D	1.475	0.99
336_K	339_G	1.473	0.99
281_F	286_I	1.467	0.99
268_D	542_L	1.458	0.99
218_N	221_G	1.445	0.99
527_R	531_D	1.442	0.99
315_Y	490_S	1.434	0.99
155_T	182_L	1.432	0.99
288_A	571_A	1.426	0.99
557_T	613_R	1.422	0.99
178_T	181_K	1.419	0.99
98_G	102_K	1.416	0.99
32_F	65_F	1.415	0.99
455_L	460_Y	1.407	0.99
548_S	551_E	1.405	0.99
308_E	491_K	1.401	0.99
362_P	376_H	1.393	0.99
206_C	213_M	1.390	0.99
200_S	210_G	1.389	0.99
532_L	619_K	1.387	0.99
200_S	211_Y	1.386	0.99
209_G	215_L	1.383	0.99
329_K	332_D	1.380	0.99
332_D	335_L	1.365	0.99
96_T	99_Q	1.365	0.99
190_K	275_D	1.364	0.99
210_G	230_L	1.361	0.99
365_M	368_E	1.357	0.99
261_K	268_D	1.355	0.99
107_E	123_G	1.354	0.99
84_N	173_F	1.352	0.99
364_Y	368_E	1.340	0.99
206_C	211_Y	1.334	0.99
42_P	46_E	1.325	0.98
527_R	563_L	1.322	0.98
205_A	211_Y	1.313	0.98
223_E	226_I	1.306	0.98
384_E	388_V	1.300	0.98
197_V	200_S	1.299	0.98
234_G	238_F	1.294	0.98
32_F	36_A	1.290	0.98
371_A	374_Y	1.279	0.98
214_V	578_A	1.273	0.98
456_Y	460_Y	1.272	0.98
78_A	529_F	1.272	0.98
334_E	337_T	1.270	0.98
134_G	507_F	1.268	0.98
249_A	252_K	1.263	0.98
407_K	419_K	1.253	0.98
436_I	439_N	1.247	0.98
212_G	215_L	1.246	0.98
433_N	437_A	1.245	0.98
210_G	215_L	1.244	0.98
496_Y	500_Q	1.243	0.98
128_K	132_T	1.241	0.98
536_R	540_R	1.237	0.98
556_V	616_Y	1.236	0.98
601_F	605_Q	1.235	0.98
282_I	286_I	1.224	0.97
365_M	372_A	1.219	0.97
229_L	233_I	1.218	0.97
205_A	572_V	1.217	0.97
332_D	336_K	1.210	0.97
149_W	153_G	1.209	0.97
96_T	548_S	1.191	0.97
326_T	329_K	1.189	0.97
78_A	530_T	1.188	0.97
226_I	230_L	1.186	0.97
284_S	288_A	1.186	0.97
364_Y	370_D	1.184	0.97
116_I	156_A	1.184	0.97
331_I	335_L	1.180	0.97
208_C	211_Y	1.180	0.97
441_Q	444_D	1.176	0.97
607_L	611_A	1.164	0.97
124_F	152_L	1.156	0.96
86_E	90_L	1.156	0.96
33_F	124_F	1.151	0.96
613_R	616_Y	1.149	0.96
76_V	528_L	1.148	0.96
532_L	616_Y	1.147	0.96
196_S	199_L	1.144	0.96
454_S	458_Y	1.143	0.96
12_T	15_K	1.142	0.96
199_L	240_S	1.129	0.96
3_F	95_I	1.123	0.96
71_F	79_F	1.122	0.96
556_V	560_L	1.115	0.96
350_S	353_R	1.113	0.96
455_L	462_H	1.109	0.95
33_F	123_G	1.109	0.95
157_C	425_V	1.108	0.95
248_R	252_K	1.105	0.95
328_L	332_D	1.105	0.95
529_F	539_Y	1.101	0.95
327_H	335_L	1.100	0.95
292_T	582_L	1.099	0.95
564_F	567_P	1.096	0.95
535_D	559_Q	1.090	0.95
120_I	156_A	1.089	0.95
613_R	617_L	1.088	0.95
288_A	601_F	1.078	0.95
541_S	544_K	1.076	0.95
372_A	377_V	1.074	0.95
14_N	86_E	1.073	0.95
528_L	605_Q	1.073	0.95
26_A	122_G	1.069	0.94
592_G	596_L	1.067	0.94
329_K	468_E	1.062	0.94
527_R	535_D	1.062	0.94
193_P	271_Y	1.059	0.94
287_S	601_F	1.058	0.94
422_V	427_K	1.055	0.94
224_P	227_I	1.055	0.94
342_Y	345_D	1.053	0.94
402_A	410_N	1.053	0.94
543_A	552_M	1.050	0.94
390_F	399_K	1.048	0.94
286_I	520_A	1.046	0.94
41_H	131_F	1.046	0.94
4_L	8_Y	1.044	0.94
38_F	512_I	1.043	0.94
368_E	375_F	1.040	0.94
469_I	476_E	1.038	0.94
440_D	444_D	1.037	0.93
25_S	68_S	1.036	0.93
419_K	422_V	1.026	0.93
74_Y	182_L	1.024	0.93
239_F	574_H	1.023	0.93
251_K	267_S	1.023	0.93
235_T	239_F	1.019	0.93
227_I	519_A	1.015	0.93
200_S	203_G	1.014	0.93
120_I	152_L	1.008	0.93
278_R	293_A	1.007	0.92
206_C	209_G	1.004	0.92
381_G	385_D	1.002	0.92
420_L	423_K	1.001	0.92
200_S	245_W	1.001	0.92
420_L	424_E	1.000	0.92
34_T	130_F	0.998	0.92
565_F	572_V	0.995	0.92
300_Y	304_V	0.993	0.92
73_L	169_F	0.991	0.92
272_R	276_N	0.986	0.92
235_T	578_A	0.983	0.92
21_F	115_S	0.982	0.92
495_Y	518_V	0.981	0.91
591_A	595_S	0.976	0.91
427_K	430_I	0.975	0.91
6_F	90_L	0.971	0.91
599_G	603_I	0.968	0.91
267_S	271_Y	0.968	0.91
519_A	524_L	0.965	0.91
77_N	84_N	0.962	0.91
612_V	619_K	0.962	0.91
385_D	388_V	0.961	0.91
11_V	22_F	0.961	0.91
332_D	337_T	0.956	0.90
330_D	333_H	0.954	0.90
36_A	61_E	0.953	0.90
21_F	24_S	0.952	0.90
593_P	597_T	0.951	0.90
304_V	308_E	0.944	0.90
68_S	162_L	0.940	0.90
193_P	244_I	0.938	0.90
74_Y	523_F	0.936	0.89
606_L	610_L	0.936	0.89
288_A	574_H	0.936	0.89
121_I	476_E	0.932	0.89
577_F	580_R	0.932	0.89
231_T	272_R	0.929	0.89
441_Q	445_Q	0.928	0.89
314_E	317_S	0.926	0.89
435_I	438_V	0.925	0.89
422_V	429_L	0.924	0.89
75_S	608_F	0.924	0.89
464_K	467_L	0.924	0.89
284_S	290_A	0.923	0.89
362_P	365_M	0.920	0.89
421_S	433_N	0.920	0.89
204_I	321_N	0.920	0.89
231_T	235_T	0.919	0.89
204_I	513_A	0.914	0.88
303_T	307_E	0.913	0.88
71_F	526_F	0.911	0.88
522_S	526_F	0.911	0.88
112_G	167_S	0.907	0.88
365_M	371_A	0.906	0.88
32_F	39_L	0.906	0.88
493_G	497_D	0.905	0.88
198_L	469_I	0.904	0.88
67_F	75_S	0.903	0.88
381_G	387_A	0.902	0.88
514_I	606_L	0.901	0.88
78_A	605_Q	0.900	0.88
321_N	327_H	0.899	0.87
279_L	282_I	0.898	0.87
203_G	210_G	0.897	0.87
528_L	559_Q	0.894	0.87
438_V	443_F	0.892	0.87
543_A	549_E	0.892	0.87
435_I	440_D	0.890	0.87
125_I	129_T	0.888	0.87
364_Y	371_A	0.888	0.87
242_S	608_F	0.887	0.87
512_I	516_F	0.886	0.87
370_D	375_F	0.885	0.87
17_A	515_V	0.884	0.87
84_N	145_L	0.882	0.86
467_L	470_S	0.881	0.86
134_G	527_R	0.881	0.86
389_Y	403_P	0.878	0.86
200_S	214_V	0.878	0.86
199_L	214_V	0.878	0.86
367_S	376_H	0.878	0.86
466_S	470_S	0.874	0.86
10_N	14_N	0.873	0.86
335_L	342_Y	0.872	0.86
526_F	601_F	0.871	0.86
108_N	170_T	0.868	0.86
101_R	171_I	0.865	0.85
284_S	289_V	0.864	0.85
151_A	507_F	0.862	0.85
605_Q	619_K	0.862	0.85
255_T	378_K	0.862	0.85
224_P	228_L	0.859	0.85
203_G	207_L	0.858	0.85
7_A	11_V	0.857	0.85
80_L	170_T	0.854	0.85
436_I	497_D	0.853	0.85
584_V	589_D	0.853	0.85
507_F	527_R	0.846	0.84
277_A	283_V	0.846	0.84
204_I	211_Y	0.846	0.84
214_V	227_I	0.845	0.84
112_G	163_F	0.845	0.84
267_S	280_F	0.844	0.84
41_H	143_L	0.843	0.84
323_K	330_D	0.840	0.84
402_A	406_L	0.840	0.84
206_C	233_I	0.839	0.84
10_N	107_E	0.839	0.84
492_A	495_Y	0.837	0.83
280_F	287_S	0.837	0.83
286_I	289_V	0.836	0.83
579_L	583_A	0.835	0.83
545_I	553_A	0.835	0.83
222_A	225_F	0.834	0.83
275_D	534_E	0.831	0.83
337_T	341_T	0.828	0.83
32_F	41_H	0.827	0.83
327_H	330_D	0.827	0.83
160_L	164_F	0.825	0.83
279_L	283_V	0.825	0.83
305_G	309_S	0.825	0.83
207_L	210_G	0.824	0.82
9_K	12_T	0.823	0.82
83_R	86_E	0.821	0.82
168_Q	172_L	0.819	0.82
489_A	494_T	0.818	0.82
208_C	213_M	0.818	0.82
211_Y	235_T	0.818	0.82
400_N	422_V	0.817	0.82
179_V	282_I	0.817	0.82
559_Q	568_F	0.816	0.82
24_S	71_F	0.815	0.82
7_A	10_N	0.814	0.82
234_G	237_F	0.813	0.82
293_A	512_I	0.813	0.82
363_V	366_I	0.813	0.82
109_M	113_V	0.811	0.81
130_F	495_Y	0.810	0.81
292_T	512_I	0.810	0.81
111_I	178_T	0.810	0.81
192_E	248_R	0.809	0.81
3_F	11_V	0.809	0.81
116_I	159_F	0.808	0.81
286_I	526_F	0.806	0.81
244_I	247_L	0.804	0.81
64_I	272_R	0.802	0.81
33_F	155_T	0.800	0.81
65_F	162_L	0.797	0.80
380_N	393_T	0.794	0.80
42_P	100_L	0.793	0.80
256_F	262_N	0.792	0.80
419_K	424_E	0.792	0.80
81_K	531_D	0.790	0.80
465_D	473_L	0.788	0.80
509_G	513_A	0.787	0.79
5_Q	9_K	0.786	0.79
585_E	589_D	0.786	0.79
63_M	67_F	0.785	0.79
363_V	369_S	0.783	0.79
403_P	408_L	0.783	0.79
26_A	30_L	0.782	0.79
151_A	155_T	0.781	0.79
24_S	276_N	0.781	0.79
296_V	299_M	0.780	0.79
41_H	71_F	0.779	0.79
112_G	116_I	0.778	0.79
231_T	574_H	0.777	0.79
330_D	334_E	0.776	0.79
342_Y	346_K	0.775	0.78
391_P	399_K	0.775	0.78
21_F	112_G	0.774	0.78
325_Q	328_L	0.774	0.78
74_Y	567_P	0.774	0.78
281_F	292_T	0.770	0.78
25_S	163_F	0.770	0.78
15_K	35_F	0.769	0.78
17_A	20_A	0.768	0.78
197_V	212_G	0.767	0.78
519_A	525_Y	0.766	0.78
141_D	441_Q	0.766	0.78
364_Y	376_H	0.765	0.78
302_S	305_G	0.765	0.78
424_E	591_A	0.764	0.77
14_N	17_A	0.763	0.77
78_A	612_V	0.763	0.77
272_R	275_D	0.762	0.77
468_E	476_E	0.761	0.77
71_F	511_F	0.760	0.77
268_D	538_R	0.759	0.77
88_G	183_I	0.759	0.77
161_L	327_H	0.757	0.77
531_D	535_D	0.757	0.77
236_Y	286_I	0.756	0.77
539_Y	555_S	0.756	0.77
431_S	554_Q	0.755	0.77
326_T	351_Y	0.755	0.77
213_M	230_L	0.754	0.77
196_S	241_Q	0.754	0.77
205_A	475_N	0.754	0.77
83_R	123_G	0.751	0.76
236_Y	282_I	0.750	0.76
379_V	387_A	0.749	0.76
542_L	545_I	0.749	0.76
362_P	408_L	0.748	0.76
423_K	430_I	0.746	0.76
292_T	578_A	0.745	0.76
98_G	550_R	0.744	0.76
211_Y	578_A	0.742	0.75
378_K	381_G	0.741	0.75
288_A	293_A	0.741	0.75
605_Q	613_R	0.740	0.75
518_V	566_F	0.740	0.75
24_S	30_L	0.738	0.75
273_L	277_A	0.738	0.75
17_A	24_S	0.736	0.75
369_S	375_F	0.736	0.75
459_S	462_H	0.735	0.75
230_L	234_G	0.735	0.75
75_S	314_E	0.733	0.74
315_Y	423_K	0.733	0.74
385_D	462_H	0.731	0.74
232_V	285_I	0.730	0.74
305_G	308_E	0.730	0.74
466_S	469_I	0.729	0.74
35_F	111_I	0.728	0.74
37_M	566_F	0.727	0.74
334_E	569_V	0.725	0.74
100_L	104_I	0.724	0.74
44_L	187_G	0.722	0.73
6_F	305_G	0.722	0.73
390_F	395_D	0.721	0.73
130_F	436_I	0.721	0.73
267_S	507_F	0.720	0.73
18_Y	35_F	0.719	0.73
574_H	605_Q	0.719	0.73
491_K	495_Y	0.718	0.73
3_F	13_R	0.717	0.73
467_L	476_E	0.716	0.73
574_H	577_F	0.715	0.73
398_F	406_L	0.714	0.73
66_V	385_D	0.713	0.72
33_F	264_I	0.711	0.72
372_A	380_N	0.711	0.72
24_S	511_F	0.711	0.72
473_L	477_I	0.710	0.72
91_L	96_T	0.710	0.72
434_A	439_N	0.709	0.72
511_F	515_V	0.708	0.72
247_L	269_L	0.708	0.72
29_V	53_A	0.708	0.72
364_Y	372_A	0.708	0.72
22_F	36_A	0.706	0.72
337_T	343_T	0.705	0.72
159_F	513_A	0.704	0.71
328_L	333_H	0.703	0.71
406_L	411_Q	0.702	0.71
74_Y	564_F	0.702	0.71
42_P	146_Y	0.701	0.71
208_C	333_H	0.700	0.71
347_I	352_V	0.699	0.71
86_E	564_F	0.699	0.71
386_E	421_S	0.698	0.71
462_H	469_I	0.698	0.71
247_L	270_V	0.696	0.71
228_L	296_V	0.694	0.70
4_L	597_T	0.693	0.70
464_K	468_E	0.692	0.70
4_L	7_A	0.691	0.70
113_V	160_L	0.690	0.70
582_L	590_V	0.689	0.70
114_M	328_L	0.688	0.70
52_I	56_G	0.686	0.70
195_P	245_W	0.685	0.69
67_F	515_V	0.684	0.69
498_T	502_P	0.683	0.69
11_V	26_A	0.683	0.69
271_Y	275_D	0.682	0.69
202_F	206_C	0.682	0.69
468_E	473_L	0.682	0.69
520_A	571_A	0.681	0.69
95_I	528_L	0.681	0.69
76_V	564_F	0.681	0.69
9_K	27_F	0.680	0.69
380_N	388_V	0.680	0.69
311_Y	494_T	0.680	0.69
24_S	271_Y	0.678	0.69
75_S	80_L	0.678	0.69
3_F	7_A	0.676	0.68
65_F	108_N	0.676	0.68
153_G	330_D	0.675	0.68
41_H	526_F	0.675	0.68
89_I	539_Y	0.674	0.68
468_E	472_S	0.673	0.68
312_E	315_Y	0.671	0.68
29_V	119_G	0.669	0.68
119_G	123_G	0.669	0.68
164_F	168_Q	0.668	0.67
610_L	613_R	0.667	0.67
535_D	616_Y	0.666	0.67
99_Q	130_F	0.665	0.67
349_V	352_V	0.665	0.67
380_N	383_K	0.664	0.67
73_L	79_F	0.664	0.67
201_L	603_I	0.662	0.67
236_Y	240_S	0.661	0.67
526_F	616_Y	0.661	0.67
332_D	344_K	0.660	0.67
21_F	32_F	0.660	0.67
424_E	427_K	0.659	0.66
520_A	578_A	0.659	0.66
71_F	267_S	0.659	0.66
333_H	337_T	0.658	0.66
90_L	513_A	0.658	0.66
430_I	433_N	0.658	0.66
256_F	259_R	0.658	0.66
214_V	574_H	0.657	0.66
288_A	522_S	0.657	0.66
25_S	34_T	0.656	0.66
149_W	152_L	0.656	0.66
572_V	576_L	0.656	0.66
159_F	162_L	0.655	0.66
58_T	62_W	0.655	0.66
125_I	319_S	0.655	0.66
34_T	331_I	0.655	0.66
374_Y	377_V	0.654	0.66
36_A	40_F	0.652	0.66
547_L	563_L	0.652	0.66
66_V	531_D	0.652	0.66
557_T	610_L	0.652	0.66
336_K	340_F	0.651	0.65
513_A	538_R	0.651	0.65
63_M	183_I	0.651	0.65
419_K	448_S	0.650	0.65
37_M	41_H	0.650	0.65
159_F	174_V	0.649	0.65
116_I	129_T	0.649	0.65
267_S	272_R	0.646	0.65
323_K	327_H	0.645	0.65
227_I	521_A	0.644	0.65
78_A	90_L	0.644	0.65
179_V	251_K	0.644	0.65
71_F	522_S	0.643	0.65
314_E	459_S	0.643	0.65
291_F	294_T	0.641	0.64
343_T	346_K	0.640	0.64
256_F	266_V	0.640	0.64
365_M	437_A	0.639	0.64
556_V	617_L	0.638	0.64
90_L	279_L	0.637	0.64
299_M	502_P	0.636	0.64
61_E	64_I	0.636	0.64
341_T	347_I	0.635	0.64
507_F	605_Q	0.634	0.63
72_V	112_G	0.633	0.63
202_F	476_E	0.633	0.63
88_G	182_L	0.632	0.63
200_S	206_C	0.632	0.63
291_F	296_V	0.631	0.63
132_T	136_Y	0.631	0.63
11_V	18_Y	0.629	0.63
347_I	353_R	0.628	0.63
367_S	375_F	0.628	0.63
72_V	85_K	0.628	0.63
67_F	519_A	0.628	0.63
409_L	433_N	0.626	0.62
264_I	267_S	0.626	0.62
34_T	173_F	0.624	0.62
291_F	520_A	0.623	0.62
537_E	540_R	0.623	0.62
457_G	460_Y	0.622	0.62
579_L	591_A	0.621	0.62
372_A	379_V	0.619	0.62
157_C	484_V	0.618	0.61
106_A	110_I	0.618	0.61
297_L	301_K	0.618	0.61
102_K	106_A	0.618	0.61
387_A	391_P	0.618	0.61
274_K	285_I	0.617	0.61
25_S	115_S	0.617	0.61
434_A	438_V	0.615	0.61
227_I	231_T	0.615	0.61
88_G	191_P	0.615	0.61
18_Y	21_F	0.613	0.61
153_G	595_S	0.613	0.61
516_F	539_Y	0.613	0.61
365_M	373_K	0.611	0.61
268_D	608_F	0.610	0.60
503_S	507_F	0.610	0.60
409_L	412_K	0.610	0.60
99_Q	102_K	0.608	0.60
10_N	13_R	0.608	0.60
363_V	367_S	0.608	0.60
525_Y	567_P	0.608	0.60
331_I	458_Y	0.607	0.60
198_L	206_C	0.607	0.60
65_F	158_G	0.606	0.60
9_K	21_F	0.605	0.60
337_T	349_V	0.604	0.60
133_V	524_L	0.604	0.60
98_G	208_C	0.603	0.60
467_L	471_Q	0.603	0.60
56_G	233_I	0.601	0.59
134_G	280_F	0.601	0.59
95_I	268_D	0.601	0.59
526_F	535_D	0.600	0.59
30_L	34_T	0.600	0.59
377_V	389_Y	0.599	0.59
298_A	499_V	0.599	0.59
289_V	524_L	0.599	0.59
493_G	496_Y	0.599	0.59
535_D	555_S	0.598	0.59
23_L	270_V	0.597	0.59
419_K	427_K	0.596	0.59
198_L	212_G	0.595	0.59
509_G	535_D	0.595	0.59
384_E	471_Q	0.594	0.58
596_L	600_G	0.594	0.58
327_H	332_D	0.594	0.58
349_V	353_R	0.594	0.58
609_F	615_S	0.593	0.58
602_F	606_L	0.593	0.58
325_Q	381_G	0.593	0.58
371_A	382_L	0.593	0.58
331_I	334_E	0.592	0.58
17_A	530_T	0.592	0.58
326_T	330_D	0.592	0.58
391_P	488_F	0.591	0.58
70_L	287_S	0.591	0.58
90_L	523_F	0.591	0.58
166_L	287_S	0.591	0.58
287_S	291_F	0.589	0.58
209_G	226_I	0.589	0.58
545_I	555_S	0.588	0.58
201_L	209_G	0.588	0.58
12_T	114_M	0.586	0.57
103_L	174_V	0.585	0.57
468_E	471_Q	0.585	0.57
87_F	90_L	0.585	0.57
200_S	208_C	0.585	0.57
84_N	180_I	0.585	0.57
40_F	43_A	0.584	0.57
184_K	188_K	0.582	0.57
478_Y	599_G	0.581	0.57
572_V	575_T	0.581	0.57
222_A	407_K	0.581	0.57
568_F	601_F	0.579	0.57
148_P	265_W	0.579	0.57
472_S	477_I	0.579	0.57
507_F	511_F	0.578	0.56
93_Q	96_T	0.578	0.56
256_F	562_I	0.577	0.56
119_G	562_I	0.577	0.56
254_K	258_L	0.576	0.56
141_D	333_H	0.576	0.56
516_F	527_R	0.576	0.56
14_N	18_Y	0.575	0.56
232_V	235_T	0.575	0.56
466_S	472_S	0.575	0.56
361_P	365_M	0.574	0.56
419_K	423_K	0.574	0.56
110_I	113_V	0.574	0.56
158_G	161_L	0.574	0.56
418_Q	445_Q	0.574	0.56
321_N	390_F	0.573	0.56
277_A	574_H	0.573	0.56
272_R	294_T	0.573	0.56
524_L	608_F	0.573	0.56
48_Y	51_N	0.572	0.56
422_V	426_K	0.572	0.56
100_L	135_A	0.571	0.56
240_S	277_A	0.570	0.55
588_S	596_L	0.569	0.55
369_S	373_K	0.569	0.55
446_L	450_G	0.569	0.55
296_V	582_L	0.569	0.55
366_I	590_V	0.568	0.55
475_N	479_G	0.568	0.55
147_M	246_I	0.568	0.55
126_F	514_I	0.568	0.55
400_N	403_P	0.568	0.55
237_F	544_K	0.567	0.55
127_S	268_D	0.566	0.55
509_G	574_H	0.566	0.55
321_N	324_E	0.565	0.55
120_I	225_F	0.565	0.55
180_I	184_K	0.565	0.55
45_K	54_K	0.564	0.55
426_K	430_I	0.564	0.55
66_V	147_M	0.563	0.54
258_L	528_L	0.563	0.54
54_K	607_L	0.562	0.54
287_S	521_A	0.562	0.54
67_F	182_L	0.562	0.54
17_A	265_W	0.561	0.54
404_D	441_Q	0.561	0.54
246_I	250_L	0.560	0.54
21_F	526_F	0.559	0.54
57_L	508_I	0.559	0.54
370_D	376_H	0.558	0.54
525_Y	535_D	0.558	0.54
401_E	430_I	0.557	0.54
329_K	333_H	0.557	0.54
459_S	479_G	0.556	0.54
13_R	539_Y	0.555	0.53
267_S	276_N	0.553	0.53
266_V	524_L	0.551	0.53
30_L	524_L	0.551	0.53
214_V	231_T	0.550	0.53
204_I	399_K	0.550	0.53
47_G	50_N	0.549	0.53
287_S	571_A	0.549	0.53
459_S	473_L	0.548	0.53
176_S	460_Y	0.548	0.53
286_I	516_F	0.548	0.53
67_F	83_R	0.548	0.53
211_Y	216_K	0.548	0.53
133_V	164_F	0.547	0.52
335_L	340_F	0.547	0.52
512_I	517_F	0.546	0.52
556_V	575_T	0.545	0.52
373_K	376_H	0.544	0.52
265_W	555_S	0.544	0.52
60_A	75_S	0.543	0.52
15_K	68_S	0.543	0.52
332_D	475_N	0.543	0.52
73_L	85_K	0.543	0.52
29_V	159_F	0.542	0.52
21_F	36_A	0.542	0.52
313_M	317_S	0.542	0.52
272_R	279_L	0.541	0.52
204_I	207_L	0.541	0.52
533_D	559_Q	0.541	0.52
530_T	557_T	0.540	0.51
347_I	603_I	0.540	0.51
196_S	210_G	0.539	0.51
6_F	9_K	0.539	0.51
28_S	543_A	0.538	0.51
333_H	336_K	0.538	0.51
476_E	479_G	0.536	0.51
71_F	525_Y	0.535	0.51
14_N	525_Y	0.534	0.51
201_L	205_A	0.534	0.51
156_A	592_G	0.534	0.51
419_K	467_L	0.533	0.51
103_L	240_S	0.533	0.51
362_P	371_A	0.533	0.51
60_A	89_I	0.533	0.51
66_V	279_L	0.533	0.51
81_K	190_K	0.532	0.50
124_F	128_K	0.532	0.50
331_I	375_F	0.531	0.50
155_T	539_Y	0.530	0.50
541_S	545_I	0.529	0.50
503_S	506_L	0.528	0.50
60_A	71_F	0.528	0.50
84_N	234_G	0.528	0.50
24_S	522_S	0.528	0.50
261_K	264_I	0.527	0.50
39_L	512_I	0.527	0.50
133_V	137_I	0.527	0.50
3_F	520_A	0.526	0.50
470_S	474_Q	0.526	0.50
448_S	569_V	0.526	0.50
89_I	495_Y	0.526	0.50
216_K	253_W	0.526	0.50
609_F	612_V	0.525	0.49
122_G	212_G	0.525	0.49
559_Q	564_F	0.523	0.49
61_E	68_S	0.522	0.49
19_L	374_Y	0.522	0.49
312_E	317_S	0.522	0.49
341_T	344_K	0.522	0.49
80_L	524_L	0.522	0.49
469_I	477_I	0.521	0.49
59_A	434_A	0.519	0.49
53_A	65_F	0.519	0.49
274_K	288_A	0.519	0.49
66_V	371_A	0.518	0.49
197_V	245_W	0.518	0.49
330_D	385_D	0.518	0.49
165_F	334_E	0.517	0.48
57_L	230_L	0.517	0.48
575_T	579_L	0.517	0.48
102_K	473_L	0.516	0.48
325_Q	339_G	0.515	0.48
207_L	234_G	0.514	0.48
70_L	579_L	0.514	0.48
176_S	542_L	0.514	0.48
425_V	442_T	0.514	0.48
71_F	243_S	0.513	0.48
180_I	551_E	0.511	0.48
443_F	500_Q	0.510	0.48
328_L	462_H	0.510	0.48
198_L	470_S	0.510	0.48
308_E	384_E	0.510	0.48
38_F	90_L	0.509	0.47
182_L	298_A	0.509	0.47
250_L	266_V	0.509	0.47
8_Y	12_T	0.508	0.47
187_G	319_S	0.508	0.47
13_R	41_H	0.508	0.47
341_T	464_K	0.508	0.47
74_Y	78_A	0.508	0.47
106_A	427_K	0.507	0.47
50_N	54_K	0.507	0.47
127_S	539_Y	0.507	0.47
251_K	508_I	0.507	0.47
124_F	331_I	0.507	0.47
304_V	495_Y	0.506	0.47
422_V	430_I	0.506	0.47
203_G	214_V	0.506	0.47
156_A	249_A	0.505	0.47
117_A	470_S	0.504	0.47
324_E	331_I	0.504	0.47
19_L	26_A	0.504	0.47
27_F	53_A	0.504	0.47
364_Y	377_V	0.504	0.47
269_L	562_I	0.504	0.47
389_Y	453_A	0.504	0.47
529_F	605_Q	0.504	0.47
283_V	290_A	0.504	0.47
60_A	511_F	0.503	0.47
538_R	573_M	0.502	0.46
196_S	214_V	0.502	0.46
76_V	523_F	0.502	0.46
280_F	601_F	0.502	0.46
121_I	336_K	0.501	0.46
25_S	75_S	0.501	0.46
147_M	547_L	0.501	0.46
129_T	152_L	0.501	0.46
71_F	265_W	0.501	0.46
341_T	381_G	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ftjA	1	0.3248	98.5	0.899	Contact Map
3is6A	2	0.3199	96.2	0.934	Contact Map
1yfbA	2	0.0836	27	0.969	Contact Map
4b4aA	1	0.3344	21.6	0.97	Contact Map
2l66A	2	0.0852	19.9	0.971	Contact Map
2mrnA	2	0.1077	18.9	0.971	Contact Map
4nawA	1	0.1415	8.2	0.975	Contact Map
3o27A	2	0.0932	6.3	0.977	Contact Map
1yu8X	1	0.1029	6.2	0.977	Contact Map
4httA	1	0.3376	5.7	0.977	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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