GREMLIN Database
IOLD - 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase
UniProt: P42415 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 637 (540)
Sequences: 14217 (9003)
Seq/√Len: 387.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
556_K559_E4.9801.00
519_D591_E3.8951.00
70_A102_A3.7941.00
425_T575_K3.6451.00
255_E275_F3.5591.00
566_Y580_D3.4531.00
249_E352_G3.1891.00
33_E82_R3.0891.00
570_T573_E3.0041.00
567_R593_K2.9721.00
221_Q357_L2.9131.00
249_E348_K2.8711.00
345_A350_T2.7031.00
429_T579_E2.6811.00
79_Q482_H2.6401.00
237_V250_L2.5851.00
223_A326_L2.5451.00
566_Y588_T2.5391.00
28_E57_H2.4631.00
274_D454_N2.4581.00
569_N573_E2.4581.00
564_K586_V2.4471.00
425_T428_E2.4401.00
328_I350_T2.4151.00
34_G59_K2.4091.00
303_I347_A2.4041.00
297_A300_I2.3471.00
475_T489_S2.3171.00
28_E54_D2.3141.00
566_Y577_A2.2891.00
90_T99_L2.2591.00
497_L561_Y2.1901.00
564_K580_D2.1751.00
553_D556_K2.1471.00
567_R591_E2.1381.00
114_L171_F2.1311.00
97_A101_A2.1201.00
428_E575_K2.1151.00
482_H485_R2.0581.00
83_R175_T2.0411.00
103_A115_L2.0401.00
226_L341_F2.0381.00
302_G305_T2.0341.00
21_Y50_A2.0231.00
557_V560_G2.0211.00
63_G69_M1.9821.00
117_P184_T1.9621.00
226_L299_L1.9481.00
235_I254_S1.9321.00
226_L324_K1.9281.00
568_A577_A1.9051.00
166_S185_I1.9051.00
555_A565_T1.8771.00
74_M78_K1.8681.00
479_K512_K1.8611.00
431_P434_S1.8511.00
145_D148_K1.8501.00
25_D29_E1.8501.00
507_I563_A1.8451.00
254_S261_L1.8381.00
496_F500_H1.8271.00
227_I301_I1.8211.00
256_A355_H1.8101.00
222_G225_E1.7691.00
225_E229_S1.7601.00
21_Y53_Q1.7591.00
435_V478_L1.7591.00
83_R114_L1.7531.00
581_A590_I1.7341.00
235_I301_I1.7241.00
235_I259_I1.7201.00
439_S491_V1.7171.00
575_K579_E1.7151.00
427_N452_H1.7131.00
256_A359_E1.7101.00
517_L589_L1.7091.00
216_S219_E1.7031.00
217_E353_K1.7031.00
252_A256_A1.6971.00
579_E583_K1.6861.00
573_E576_A1.6691.00
54_D57_H1.6641.00
159_R162_Q1.6621.00
335_A344_V1.6601.00
559_E564_K1.6391.00
564_K588_T1.6371.00
439_S495_S1.6331.00
426_I490_I1.6311.00
303_I328_I1.6291.00
470_Y474_G1.6211.00
48_G60_V1.6181.00
17_L25_D1.6041.00
251_V255_E1.5951.00
155_D185_I1.5941.00
37_T60_V1.5901.00
80_M481_A1.5711.00
424_L428_E1.5711.00
460_H478_L1.5671.00
258_N277_N1.5381.00
248_D252_A1.5381.00
569_N593_K1.5371.00
506_A563_A1.5251.00
230_S233_P1.5251.00
296_Q379_E1.5201.00
555_A567_R1.5191.00
261_L271_V1.5101.00
99_L115_L1.5041.00
151_S184_T1.4991.00
576_A580_D1.4991.00
227_I299_L1.4971.00
479_K511_K1.4951.00
23_H187_I1.4891.00
152_R181_G1.4761.00
421_T571_V1.4621.00
26_G168_L1.4611.00
503_L563_A1.4531.00
516_L590_I1.4401.00
116_I187_I1.4371.00
63_G72_A1.4351.00
506_A513_I1.4331.00
103_A113_V1.4291.00
434_S486_E1.4271.00
68_G502_E1.4231.00
253_I257_Y1.4231.00
299_L326_L1.4211.00
23_H167_L1.4211.00
224_A354_L1.4121.00
160_P194_E1.4111.00
500_H557_V1.4101.00
379_E383_L1.4061.00
516_L578_L1.4051.00
576_A579_E1.4031.00
458_T485_R1.4021.00
421_T425_T1.3881.00
431_P486_E1.3861.00
429_T575_K1.3801.00
219_E222_G1.3731.00
425_T429_T1.3701.00
25_D28_E1.3661.00
96_A117_P1.3651.00
422_A592_M1.3551.00
430_I488_Y1.3531.00
114_L174_M1.3471.00
468_M498_M1.3441.00
230_S299_L1.3371.00
488_Y582_K1.3331.00
224_A357_L1.3291.00
30_P171_F1.3291.00
59_K509_Y1.3271.00
252_A355_H1.3241.00
122_A190_D1.3231.00
24_V54_D1.3201.00
33_E59_K1.3181.00
303_I351_L1.3161.00
253_I351_L1.3151.00
512_K586_V1.3101.00
514_N581_A1.3091.00
157_I163_L1.3061.00
336_Y339_D1.3011.00
476_L506_A1.2991.00
516_L592_M1.2931.00
215_P350_T1.2921.00
74_M105_T1.2831.00
480_L511_K1.2781.00
432_E454_N1.2761.00
18_N21_Y1.2741.00
250_L351_L1.2731.00
253_I355_H1.2721.00
220_L357_L1.2691.00
417_L592_M1.2691.00
324_K340_A1.2681.00
167_L185_I1.2681.00
234_V297_A1.2661.00
70_A99_L1.2611.00
574_L592_M1.2601.00
30_P168_L1.2591.00
479_K486_E1.2591.00
34_G480_L1.2551.00
83_R171_F1.2541.00
435_V482_H1.2501.00
563_A589_L1.2491.00
162_Q165_S1.2471.00
557_V561_Y1.2381.00
36_F76_Y1.2351.00
348_K352_G1.2331.00
378_A382_R1.2331.00
417_L422_A1.2321.00
20_Q50_A1.2321.00
221_Q225_E1.2321.00
555_A559_E1.2291.00
279_L293_A1.2241.00
435_V487_V1.2241.00
577_A590_I1.2181.00
61_Y480_L1.2151.00
19_Q163_L1.2131.00
77_S112_P1.2111.00
558_A563_A1.2081.00
489_S515_V1.2071.00
165_S169_R1.2041.00
521_S551_N1.1941.00
349_V352_G1.1911.00
512_K585_D1.1871.00
346_D349_V1.1851.00
381_E384_S1.1841.00
32_V87_A1.1761.00
504_I508_Q1.1751.00
486_E582_K1.1751.00
104_G465_Y1.1741.00
76_Y481_A1.1711.00
432_E455_V1.1691.00
479_K483_P1.1691.00
251_V272_E1.1651.00
188_S191_V1.1631.00
25_D54_D1.1611.00
224_A228_K1.1541.00
556_K560_G1.1531.00
233_P298_D1.1531.00
100_V146_A1.1471.00
353_K356_G1.1451.00
251_V271_V1.1451.00
252_A255_E1.1441.00
241_A250_L1.1411.00
558_A589_L1.1411.00
292_K296_Q1.1401.00
222_G226_L1.1371.00
75_A79_Q1.1361.00
217_E357_L1.1361.00
268_K273_A1.1301.00
35_I51_L1.1281.00
376_W380_R1.1221.00
235_I253_I1.1201.00
26_G167_L1.1141.00
74_M111_I1.1141.00
255_E277_N1.1131.00
223_A343_V1.1101.00
263_E278_N1.1071.00
173_V183_A1.1041.00
88_V99_L1.1021.00
134_E145_D1.1011.00
90_T115_L1.1011.00
252_A352_G1.1001.00
378_A381_E1.1001.00
224_A358_L1.0991.00
100_V150_V1.0981.00
21_Y25_D1.0971.00
271_V275_F1.0921.00
155_D169_R1.0881.00
574_L578_L1.0881.00
155_D166_S1.0881.00
79_Q478_L1.0871.00
123_T190_D1.0871.00
479_K487_V1.0851.00
22_I196_Y1.0841.00
122_A194_E1.0821.00
249_E355_H1.0801.00
107_L182_P1.0801.00
215_P353_K1.0721.00
228_K359_E1.0711.00
230_S298_D1.0701.00
214_Q353_K1.0691.00
565_T589_L1.0691.00
232_K296_Q1.0691.00
254_S271_V1.0641.00
302_G307_Y1.0641.00
237_V241_A1.0621.00
566_Y590_I1.0601.00
249_E252_A1.0601.00
151_S154_W1.0581.00
235_I250_L1.0571.00
18_N195_A1.0541.00
146_A150_V1.0541.00
479_K484_D1.0521.00
228_K361_Y1.0521.00
88_V115_L1.0521.00
433_D485_R1.0501.00
223_A341_F1.0491.00
68_G499_L1.0491.00
125_Q156_R1.0461.00
157_I166_S1.0451.00
97_A146_A1.0431.00
44_V47_I1.0381.00
50_A53_Q1.0351.00
471_E489_S1.0301.00
234_V262_V1.0281.00
568_A573_E1.0271.00
514_N588_T1.0261.00
436_I451_W1.0251.00
252_A359_E1.0221.00
17_L195_A1.0221.00
248_D251_V1.0221.00
229_S299_L1.0201.00
22_I164_M1.0161.00
430_I436_I1.0141.00
343_V350_T1.0141.00
61_Y509_Y1.0111.00
503_L589_L1.0101.00
568_A574_L1.0071.00
34_G61_Y1.0061.00
262_V279_L1.0051.00
374_D378_A1.0041.00
418_P598_T1.0011.00
558_A565_T0.9981.00
229_S324_K0.9971.00
564_K584_Q0.9951.00
228_K358_L0.9931.00
72_A506_A0.9921.00
514_N590_I0.9911.00
154_W184_T0.9881.00
254_S277_N0.9881.00
23_H116_I0.9881.00
486_E514_N0.9861.00
472_V496_F0.9831.00
70_A88_V0.9801.00
500_H561_Y0.9791.00
47_I187_I0.9761.00
496_F517_L0.9681.00
584_Q588_T0.9681.00
256_A360_G0.9671.00
35_I87_A0.9671.00
517_L554_Y0.9631.00
288_L292_K0.9621.00
479_K586_V0.9601.00
96_A147_L0.9571.00
437_I489_S0.9541.00
521_S593_K0.9531.00
223_A299_L0.9531.00
119_D186_C0.9531.00
423_L490_I0.9521.00
563_A587_S0.9511.00
253_I358_L0.9491.00
218_R221_Q0.9481.00
349_V353_K0.9481.00
144_N154_W0.9461.00
506_A515_V0.9441.00
555_A591_E0.9401.00
580_D583_K0.9381.00
314_S317_A0.9371.00
78_K111_I0.9361.00
175_T180_A0.9351.00
26_G30_P0.9341.00
503_L515_V0.9321.00
82_R175_T0.9291.00
114_L175_T0.9261.00
437_I487_V0.9251.00
23_H47_I0.9231.00
234_V294_A0.9231.00
19_Q160_P0.9201.00
510_N585_D0.9201.00
382_R392_A0.9191.00
581_A588_T0.9191.00
110_N179_K0.9151.00
249_E351_L0.9131.00
234_V300_I0.9121.00
380_R383_L0.9101.00
429_T578_L0.9101.00
518_F594_V0.9071.00
577_A581_A0.9061.00
153_Y166_S0.9041.00
70_A113_V0.9031.00
496_F589_L0.9031.00
223_A226_L0.9021.00
455_V458_T0.9001.00
272_E275_F0.9001.00
447_L490_I0.8991.00
51_L58_L0.8991.00
514_N582_K0.8981.00
494_G523_F0.8971.00
251_V275_F0.8971.00
339_D342_Q0.8971.00
225_E361_Y0.8961.00
214_Q349_V0.8941.00
169_R173_V0.8911.00
377_L381_E0.8881.00
103_A147_L0.8861.00
153_Y173_V0.8831.00
513_I587_S0.8801.00
379_E382_R0.8791.00
335_A342_Q0.8751.00
477_G481_A0.8751.00
247_R251_V0.8741.00
421_T574_L0.8741.00
422_A518_F0.8691.00
18_N50_A0.8691.00
97_A104_G0.8661.00
246_A249_E0.8621.00
17_L22_I0.8621.00
504_I561_Y0.8601.00
153_Y170_A0.8591.00
101_A467_C0.8561.00
506_A587_S0.8551.00
75_A474_G0.8541.00
225_E228_K0.8521.00
328_I343_V0.8511.00
226_L326_L0.8511.00
425_T574_L0.8501.00
375_E378_A0.8481.00
559_E565_T0.8471.00
32_V171_F0.8421.00
242_K270_T0.8391.00
100_V147_L0.8381.00
34_G76_Y0.8371.00
49_Q52_E0.8371.00
232_K298_D0.8371.00
217_E221_Q0.8351.00
152_R183_A0.8351.00
144_N156_R0.8341.00
508_Q550_L0.8321.00
490_I518_F0.8321.00
282_M294_A0.8321.00
174_M183_A0.8311.00
237_V263_E0.8281.00
423_L518_F0.8261.00
519_D593_K0.8261.00
103_A150_V0.8221.00
434_S488_Y0.8211.00
26_G29_E0.8191.00
427_N451_W0.8181.00
90_T117_P0.8171.00
222_G341_F0.8171.00
274_D432_E0.8151.00
273_A278_N0.8131.00
160_P164_M0.8121.00
429_T582_K0.8121.00
46_G193_G0.8101.00
235_I303_I0.8091.00
573_E577_A0.8081.00
299_L324_K0.8071.00
514_N585_D0.8071.00
77_S113_V0.8051.00
257_Y358_L0.8041.00
87_A114_L0.8041.00
39_F62_Q0.8021.00
79_Q460_H0.8011.00
215_P220_L0.8001.00
572_E576_A0.7941.00
145_D149_P0.7931.00
67_Q98_N0.7931.00
187_I192_E0.7901.00
228_K356_G0.7891.00
565_T591_E0.7891.00
220_L353_K0.7891.00
553_D567_R0.7881.00
507_I587_S0.7871.00
488_Y516_L0.7861.00
472_V515_V0.7851.00
76_Y82_R0.7841.00
237_V261_L0.7841.00
30_P175_T0.7821.00
553_D559_E0.7821.00
521_S596_P0.7781.00
239_G266_A0.7781.00
153_Y169_R0.7771.00
63_G68_G0.7771.00
38_I99_L0.7741.00
580_D584_Q0.7721.00
223_A350_T0.7711.00
443_L495_S0.7691.00
423_L451_W0.7691.00
476_L511_K0.7681.00
417_L571_V0.7671.00
433_D455_V0.7671.00
33_E76_Y0.7641.00
438_C461_L0.7611.00
89_S116_I0.7611.00
577_A580_D0.7581.00
79_Q481_A0.7571.00
71_H467_C0.7571.00
233_P259_I0.7551.00
35_I89_S0.7541.00
312_T315_K0.7531.00
104_G150_V0.7531.00
49_Q537_S0.7531.00
77_S111_I0.7521.00
515_V563_A0.7491.00
490_I516_L0.7491.00
156_R186_C0.7481.00
265_Q448_Q0.7481.00
430_I434_S0.7471.00
427_N454_N0.7461.00
215_P349_V0.7461.00
271_V278_N0.7431.00
472_V491_V0.7421.00
332_R344_V0.7421.00
246_A348_K0.7421.00
497_L552_V0.7391.00
438_C459_Y0.7391.00
117_P186_C0.7381.00
227_I257_Y0.7371.00
44_V48_G0.7351.00
228_K357_L0.7331.00
497_L554_Y0.7321.00
27_K87_A0.7301.00
44_V89_S0.7301.00
417_L570_T0.7281.00
70_A115_L0.7281.00
36_F72_A0.7261.00
489_S495_S0.7261.00
568_A590_I0.7251.00
235_I261_L0.7241.00
439_S471_E0.7231.00
153_Y183_A0.7231.00
119_D125_Q0.7231.00
475_T513_I0.7191.00
516_L574_L0.7171.00
59_K483_P0.7171.00
350_T353_K0.7161.00
152_R173_V0.7141.00
496_F554_Y0.7131.00
97_A100_V0.7121.00
52_E537_S0.7121.00
157_I188_S0.7101.00
506_A511_K0.7061.00
329_N334_Q0.7041.00
352_G355_H0.7031.00
47_I192_E0.7011.00
437_I460_H0.6991.00
111_I470_Y0.6981.00
28_E33_E0.6981.00
486_E512_K0.6971.00
91_S131_Q0.6971.00
219_E223_A0.6950.99
272_E454_N0.6950.99
376_W379_E0.6950.99
122_A188_S0.6950.99
241_A270_T0.6940.99
435_V485_R0.6940.99
106_A113_V0.6940.99
219_E343_V0.6930.99
233_P299_L0.6920.99
352_G356_G0.6910.99
33_E57_H0.6910.99
263_E273_A0.6890.99
98_N101_A0.6880.99
512_K587_S0.6880.99
90_T96_A0.6880.99
497_L500_H0.6870.99
422_A516_L0.6860.99
563_A586_V0.6840.99
19_Q22_I0.6840.99
375_E379_E0.6830.99
245_G457_N0.6830.99
353_K357_L0.6820.99
277_N377_L0.6820.99
144_N148_K0.6800.99
377_L380_R0.6800.99
247_R456_P0.6790.99
356_G359_E0.6780.99
527_N531_M0.6760.99
507_I562_G0.6750.99
553_D591_E0.6750.99
164_M168_L0.6750.99
438_C447_L0.6750.99
212_R346_D0.6740.99
122_A158_T0.6730.99
240_G329_N0.6700.99
49_Q53_Q0.6700.99
29_E198_F0.6690.99
577_A588_T0.6690.99
301_I328_I0.6680.99
160_P196_Y0.6680.99
335_A339_D0.6670.99
514_N586_V0.6670.99
64_K508_Q0.6660.99
531_M538_Y0.6650.99
75_A477_G0.6650.99
302_G325_F0.6640.99
269_S273_A0.6630.99
152_R177_P0.6630.99
169_R172_E0.6620.99
244_S346_D0.6610.99
507_I550_L0.6610.99
21_Y54_D0.6610.99
522_G527_N0.6600.99
160_P191_V0.6600.99
488_Y514_N0.6600.99
381_E391_E0.6580.99
380_R384_S0.6570.99
249_E253_I0.6540.99
22_I25_D0.6540.99
236_L302_G0.6520.99
434_S485_R0.6520.99
254_S257_Y0.6520.99
173_V179_K0.6500.99
107_L152_R0.6490.99
546_D549_I0.6440.99
29_E202_F0.6420.99
226_L229_S0.6420.99
152_R179_K0.6420.99
47_I89_S0.6410.99
437_I478_L0.6410.99
108_A465_Y0.6410.99
527_N548_Q0.6400.99
283_G286_G0.6390.99
491_V499_L0.6390.99
472_V502_E0.6370.99
355_H359_E0.6350.99
46_G192_E0.6350.99
126_P132_Q0.6350.99
44_V118_A0.6340.99
552_V560_G0.6340.99
433_D486_E0.6320.99
460_H470_Y0.6310.99
236_L264_T0.6300.99
473_S502_E0.6300.99
420_T598_T0.6290.99
116_I185_I0.6280.99
258_N377_L0.6260.99
38_I523_F0.6260.99
437_I471_E0.6240.99
422_A574_L0.6220.99
147_L184_T0.6220.99
257_Y277_N0.6210.99
256_A358_L0.6200.99
119_D156_R0.6190.99
566_Y584_Q0.6180.99
99_L117_P0.6170.99
17_L21_Y0.6170.99
570_T576_A0.6160.99
65_N98_N0.6160.99
327_N339_D0.6150.99
166_S169_R0.6150.99
28_E58_L0.6150.99
426_I516_L0.6140.99
585_D588_T0.6120.99
28_E56_G0.6110.99
234_V293_A0.6110.99
71_H105_T0.6100.99
35_I58_L0.6080.99
214_Q217_E0.6080.99
443_L518_F0.6080.99
122_A191_V0.6080.99
476_L505_T0.6070.99
112_P174_M0.6020.99
155_D183_A0.6010.99
415_T570_T0.6000.99
130_L466_S0.5990.99
236_L305_T0.5990.99
40_G91_S0.5980.98
279_L290_A0.5980.98
475_T487_V0.5970.98
497_L501_S0.5960.98
220_L354_L0.5950.98
268_K453_S0.5930.98
491_V515_V0.5920.98
83_R86_Y0.5910.98
72_A480_L0.5910.98
500_H560_G0.5910.98
215_P345_A0.5890.98
80_M477_G0.5890.98
236_L300_I0.5880.98
231_K298_D0.5880.98
376_W381_E0.5860.98
232_K376_W0.5850.98
34_G82_R0.5850.98
78_K109_N0.5840.98
70_A103_A0.5830.98
250_L254_S0.5830.98
447_L459_Y0.5830.98
64_K504_I0.5810.98
266_A463_Y0.5800.98
24_V51_L0.5790.98
76_Y80_M0.5760.98
172_E177_P0.5740.98
580_D588_T0.5730.98
251_V455_V0.5720.98
76_Y86_Y0.5720.98
334_Q337_K0.5710.98
478_L487_V0.5710.98
171_F175_T0.5710.98
105_T109_N0.5700.98
292_K295_R0.5700.98
269_S458_T0.5700.98
526_I530_Q0.5700.98
228_K231_K0.5700.98
435_V460_H0.5670.98
421_T575_K0.5670.98
122_A159_R0.5660.98
251_V254_S0.5650.98
99_L102_A0.5650.98
527_N596_P0.5650.98
190_D194_E0.5640.98
568_A576_A0.5640.98
472_V506_A0.5640.98
114_L185_I0.5630.98
212_R216_S0.5630.98
347_A352_G0.5620.98
170_A185_I0.5610.98
531_M536_G0.5610.98
578_L582_K0.5590.98
552_V557_V0.5590.98
258_N276_A0.5580.98
162_Q166_S0.5580.98
423_L447_L0.5570.98
26_G164_M0.5570.98
507_I510_N0.5560.98
97_A133_M0.5550.98
20_Q27_K0.5540.98
241_A351_L0.5540.98
252_A356_G0.5540.98
74_M474_G0.5540.98
331_S334_Q0.5540.98
114_L183_A0.5540.98
480_L509_Y0.5540.98
291_N295_R0.5530.98
79_Q435_V0.5530.98
438_C471_E0.5530.98
536_G539_Y0.5520.97
415_T571_V0.5510.97
118_A192_E0.5500.97
416_E595_L0.5500.97
514_N584_Q0.5500.97
505_T511_K0.5500.97
357_L361_Y0.5490.97
468_M526_I0.5490.97
246_A347_A0.5490.97
220_L343_V0.5480.97
496_F515_V0.5460.97
107_L181_G0.5450.97
350_T354_L0.5450.97
430_I451_W0.5450.97
49_Q530_Q0.5450.97
504_I552_V0.5440.97
83_R88_V0.5440.97
204_V207_V0.5430.97
157_I185_I0.5420.97
439_S489_S0.5420.97
107_L151_S0.5420.97
67_Q499_L0.5420.97
336_Y342_Q0.5390.97
413_L572_E0.5380.97
43_N92_V0.5380.97
19_Q26_G0.5370.97
491_V495_S0.5370.97
313_S316_T0.5360.97
87_A171_F0.5360.97
263_E268_K0.5360.97
566_Y576_A0.5340.97
61_Y505_T0.5340.97
553_D560_G0.5330.97
503_L506_A0.5330.97
71_H102_A0.5320.97
442_S525_C0.5320.97
438_C441_G0.5320.97
539_Y546_D0.5310.97
59_K480_L0.5310.97
515_V589_L0.5310.97
526_I529_L0.5310.97
231_K375_E0.5300.97
242_K457_N0.5290.97
455_V485_R0.5290.97
423_L427_N0.5280.97
69_M90_T0.5280.97
172_E175_T0.5270.97
105_T467_C0.5270.97
148_K154_W0.5260.97
559_E566_Y0.5260.97
39_F48_G0.5250.97
116_I167_L0.5240.97
419_Q446_D0.5240.97
357_L360_G0.5230.97
216_S349_V0.5230.97
407_N410_A0.5220.96
117_P135_Q0.5220.96
224_A253_I0.5210.96
223_A301_I0.5210.96
472_V500_H0.5210.96
510_N586_V0.5210.96
248_D255_E0.5210.96
564_K585_D0.5210.96
239_G306_R0.5210.96
430_I582_K0.5210.96
273_A452_H0.5200.96
519_D554_Y0.5200.96
160_P163_L0.5180.96
242_K247_R0.5170.96
503_L507_I0.5170.96
514_N578_L0.5170.96
161_E197_D0.5160.96
500_H503_L0.5160.96
473_S499_L0.5150.96
22_I26_G0.5140.96
326_L341_F0.5130.96
179_K331_S0.5130.96
223_A354_L0.5120.96
91_S96_A0.5120.96
258_N360_G0.5110.96
38_I498_M0.5110.96
77_S83_R0.5100.96
263_E270_T0.5100.96
382_R391_E0.5090.96
168_L172_E0.5090.96
38_I63_G0.5090.96
87_A116_I0.5080.96
324_K341_F0.5080.96
215_P343_V0.5080.96
65_N101_A0.5080.96
571_V575_K0.5070.96
442_S524_G0.5070.96
436_I459_Y0.5060.96
384_S391_E0.5060.96
409_Y413_L0.5060.96
358_L361_Y0.5050.96
45_L526_I0.5040.96
227_I259_I0.5040.96
437_I474_G0.5030.96
497_L504_I0.5020.96
36_F480_L0.5010.96
552_V561_Y0.5010.96
22_I198_F0.5000.96
517_L591_E0.5000.96
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ozhA 4 0.8571 100 0.218 Contact Map
1t9bA 2 0.9042 100 0.22 Contact Map
4rjjA 5 0.8666 100 0.222 Contact Map
1ybhA 4 0.898 100 0.222 Contact Map
2panA 3 0.9152 100 0.224 Contact Map
2ihtA 4 0.8477 100 0.225 Contact Map
3eyaA 5 0.8257 100 0.231 Contact Map
2uz1A 4 0.8603 100 0.232 Contact Map
2x7jA 4 0.8838 100 0.233 Contact Map
2pgnA 4 0.8854 100 0.234 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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