GREMLIN Database
YTEA - Uncharacterized protein YteA
UniProt: P42408 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 239 (210)
Sequences: 296 (253)
Seq/√Len: 17.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
151_Y159_D6.3351.00
97_S115_L4.8291.00
61_E64_K3.8121.00
95_E113_T3.6761.00
21_I79_I3.1880.99
10_L86_I3.1810.99
154_E158_Q3.0580.99
11_K87_E2.6540.97
128_R132_E2.6410.97
166_S169_P2.5900.97
18_K22_L2.5760.97
136_F142_D2.5600.96
192_N197_E2.5460.96
17_T75_H2.4750.96
97_S118_Y2.4550.95
164_G169_P2.4420.95
24_R72_E2.3770.95
194_E197_E2.3130.94
128_R131_E2.0220.88
156_S160_V1.9870.87
93_I100_E1.9640.86
60_Y63_E1.9480.86
39_Y48_Y1.9390.86
56_A60_Y1.9330.85
22_L80_E1.9180.85
62_R65_D1.9100.85
155_D158_Q1.8790.84
115_L118_Y1.8630.83
139_F153_S1.7930.81
37_F42_W1.7360.79
142_D153_S1.6640.75
10_L103_F1.6570.75
149_A188_E1.6500.75
3_T6_Q1.6350.74
11_K86_I1.6070.73
31_F72_E1.5740.71
138_Q153_S1.5640.71
213_Q217_H1.5520.70
18_K80_E1.5490.70
203_D206_G1.5130.68
79_I145_E1.5010.67
165_N169_P1.4810.66
61_E65_D1.4760.66
56_A93_I1.4590.65
138_Q142_D1.4410.64
17_T107_E1.4300.64
84_K88_N1.4260.63
99_K117_E1.4040.62
9_H107_E1.3930.61
136_F139_F1.3910.61
137_G142_D1.3750.60
171_D183_T1.3620.60
166_S171_D1.3460.59
160_V193_T1.3410.58
196_Y199_F1.3370.58
11_K90_T1.3190.57
167_Q172_M1.3160.57
75_H111_T1.3110.57
152_D158_Q1.3000.56
109_L112_A1.2860.55
59_L63_E1.2840.55
74_E78_D1.2730.54
164_G168_T1.2700.54
135_P138_Q1.2650.54
18_K87_E1.2610.54
142_D154_E1.2430.53
21_I24_R1.2220.51
154_E188_E1.2180.51
17_T20_D1.2140.51
78_D111_T1.2090.51
56_A63_E1.2080.50
167_Q171_D1.1860.49
165_N171_D1.1700.48
8_Q11_K1.1620.48
58_E97_S1.1500.47
95_E114_T1.1050.44
47_A55_Q1.1040.44
94_C97_S1.0940.44
199_F203_D1.0910.43
151_Y157_Y1.0880.43
164_G171_D1.0870.43
119_S122_D1.0860.43
7_L86_I1.0760.43
82_S85_A1.0710.42
201_A204_I1.0670.42
135_P142_D1.0620.42
196_Y214_S1.0560.41
81_H113_T1.0500.41
29_D77_R1.0480.41
136_F154_E1.0400.40
13_E17_T1.0360.40
5_E9_H1.0310.40
85_A113_T1.0300.40
188_E214_S1.0300.40
27_D180_D1.0250.40
76_L156_S1.0220.39
94_C115_L1.0170.39
167_Q170_Q1.0010.38
57_T63_E0.9990.38
136_F153_S0.9920.38
56_A130_I0.9910.38
8_Q116_A0.9900.38
2_L6_Q0.9900.38
161_E165_N0.9870.37
22_L79_I0.9830.37
200_I204_I0.9700.36
139_F148_R0.9680.36
77_R88_N0.9640.36
151_Y163_Y0.9560.36
80_E100_E0.9420.35
202_T206_G0.9410.35
116_A119_S0.9380.35
5_E16_Q0.9360.35
164_G167_Q0.9320.34
14_L44_E0.9280.34
81_H95_E0.9240.34
112_A144_D0.9230.34
40_D79_I0.9160.33
27_D30_H0.9140.33
54_D152_D0.9130.33
209_I217_H0.9100.33
19_K87_E0.9020.33
41_S61_E0.9000.33
201_A207_K0.8980.32
73_R141_F0.8970.32
94_C155_D0.8960.32
63_E183_T0.8950.32
66_I187_E0.8880.32
142_D185_N0.8870.32
3_T12_N0.8790.31
6_Q103_F0.8760.31
168_T183_T0.8750.31
211_V214_S0.8740.31
18_K125_S0.8740.31
79_I90_T0.8730.31
153_S157_Y0.8590.30
119_S212_Y0.8580.30
139_F142_D0.8570.30
156_S161_E0.8560.30
176_P181_D0.8550.30
95_E187_E0.8550.30
212_Y217_H0.8540.30
61_E108_A0.8520.30
129_P132_E0.8500.30
158_Q188_E0.8470.30
118_Y202_T0.8450.30
112_A157_Y0.8410.30
139_F152_D0.8410.30
39_Y47_A0.8320.29
85_A150_P0.8280.29
86_I126_K0.8250.29
201_A212_Y0.8200.28
78_D113_T0.8150.28
140_E173_E0.8080.28
79_I160_V0.8050.28
26_K93_I0.8040.28
165_N168_T0.8010.28
136_F193_T0.8000.27
173_E202_T0.7970.27
119_S196_Y0.7960.27
37_F55_Q0.7950.27
142_D158_Q0.7920.27
7_L79_I0.7900.27
21_I76_L0.7810.27
109_L127_D0.7810.27
135_P155_D0.7790.26
18_K76_L0.7790.26
152_D155_D0.7760.26
16_Q80_E0.7720.26
86_I117_E0.7700.26
69_D144_D0.7630.26
157_Y165_N0.7550.25
189_N200_I0.7520.25
153_S158_Q0.7510.25
19_K22_L0.7510.25
135_P140_E0.7490.25
185_N191_G0.7450.25
26_K130_I0.7400.25
69_D73_R0.7390.25
42_W55_Q0.7380.25
55_Q58_E0.7370.25
41_S65_D0.7370.25
81_H85_A0.7270.24
30_H73_R0.7260.24
10_L201_A0.7210.24
99_K209_I0.7190.24
47_A86_I0.7180.24
60_Y191_G0.7130.23
10_L28_N0.7110.23
12_N16_Q0.7020.23
59_L67_A0.7010.23
98_G106_L0.6940.23
149_A154_E0.6940.23
16_Q19_K0.6870.22
160_V163_Y0.6860.22
53_G165_N0.6850.22
71_H124_V0.6830.22
214_S217_H0.6820.22
31_F111_T0.6730.22
86_I124_V0.6700.22
20_D96_V0.6700.22
199_F202_T0.6700.22
136_F155_D0.6670.22
36_A55_Q0.6660.22
150_P195_S0.6650.21
90_T187_E0.6620.21
8_Q126_K0.6620.21
169_P179_Y0.6620.21
199_F214_S0.6610.21
58_E94_C0.6580.21
7_L12_N0.6540.21
201_A211_V0.6530.21
196_Y200_I0.6460.21
141_F144_D0.6440.21
70_L90_T0.6420.21
64_K68_L0.6390.20
71_H75_H0.6380.20
85_A96_V0.6360.20
211_V217_H0.6350.20
172_M183_T0.6350.20
53_G56_A0.6280.20
81_H189_N0.6280.20
151_Y154_E0.6230.20
153_S156_S0.6180.20
53_G97_S0.6170.20
80_E190_I0.6160.20
114_T197_E0.6160.20
58_E115_L0.6130.19
191_G194_E0.6080.19
60_Y95_E0.6060.19
18_K56_A0.6050.19
48_Y56_A0.6050.19
74_E157_Y0.6050.19
12_N99_K0.6040.19
35_S88_N0.6030.19
168_T171_D0.6020.19
8_Q130_I0.5960.19
84_K109_L0.5920.19
25_F63_E0.5910.19
136_F158_Q0.5880.18
141_F148_R0.5860.18
11_K15_E0.5860.18
174_N184_M0.5840.18
82_S157_Y0.5820.18
17_T180_D0.5750.18
134_T150_P0.5730.18
15_E98_G0.5720.18
17_T56_A0.5710.18
119_S161_E0.5710.18
10_L202_T0.5700.18
118_Y203_D0.5700.18
21_I72_E0.5690.18
39_Y192_N0.5680.18
61_E68_L0.5680.18
16_Q53_G0.5650.18
93_I97_S0.5650.18
198_N214_S0.5630.18
23_N156_S0.5620.18
139_F174_N0.5610.18
149_A198_N0.5600.17
153_S192_N0.5570.17
84_K87_E0.5560.17
154_E187_E0.5550.17
13_E205_T0.5550.17
161_E170_Q0.5530.17
142_D191_G0.5520.17
153_S161_E0.5510.17
40_D178_S0.5510.17
159_D162_K0.5490.17
8_Q15_E0.5480.17
19_K23_N0.5430.17
75_H85_A0.5430.17
168_T178_S0.5420.17
161_E176_P0.5410.17
58_E179_Y0.5400.17
134_T167_Q0.5360.17
95_E133_E0.5360.17
142_D151_Y0.5350.17
24_R70_L0.5350.17
53_G57_T0.5350.17
189_N211_V0.5330.17
150_P193_T0.5310.17
60_Y93_I0.5290.16
85_A119_S0.5290.16
53_G167_Q0.5290.16
34_N99_K0.5280.16
103_F144_D0.5280.16
60_Y153_S0.5260.16
176_P209_I0.5240.16
88_N117_E0.5240.16
112_A176_P0.5220.16
138_Q141_F0.5210.16
58_E91_Y0.5190.16
4_K196_Y0.5180.16
85_A122_D0.5180.16
187_E210_T0.5160.16
71_H167_Q0.5150.16
37_F62_R0.5130.16
77_R116_A0.5120.16
48_Y78_D0.5120.16
31_F66_I0.5120.16
161_E171_D0.5110.16
164_G178_S0.5100.16
43_G88_N0.5090.16
4_K88_N0.5090.16
80_E88_N0.5080.16
59_L157_Y0.5080.16
26_K84_K0.5080.16
137_G184_M0.5060.16
29_D124_V0.5050.16
88_N205_T0.5030.16
207_K213_Q0.5030.16
200_I214_S0.5010.16
65_D168_T0.5010.16
155_D179_Y0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ijjA 1 0.4895 100 0.677 Contact Map
1tjlA 2 0.5063 100 0.703 Contact Map
2kq9A 1 0.4351 99.9 0.736 Contact Map
2kgoA 1 0.3598 99.8 0.774 Contact Map
2lo3A 1 0.1841 66.8 0.954 Contact Map
3w0fA 1 0.477 54.7 0.958 Contact Map
3mhsE 1 0.3556 51.2 0.959 Contact Map
1k3xA 1 0.4519 51 0.959 Contact Map
1lkoA 3 0.5272 47.5 0.959 Contact Map
3pwfA 4 0.4979 45.3 0.96 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0081 seconds.