YXIO - BACSU - GREMLIN Contacts

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YXIO - Uncharacterized MFS-type transporter YxiO

UniProt:	P42306	Sequences: MMKRFTKQENSWVLYDWANSAYSIVVTTAVFPLFYKSAAAESGVSAAQSTAYLGYTIAISTFILAMLGPILGTIADYEGCKKKFFGFFVSAGVASTAMLAFIPSEHWLLLLLFYTVSAIGFSGANVFYDAFLVDVTPEKRMNLVSARGFGLGYIGSTIPFIISIAVILLAQAETIPVSVSAASQLSFFITAAWWGLFTIPMIKHVHQRYYIKKEPHIVINSFKRLGQTMKRIRQYRALFLFLLAYFFYIDGVGTIITMSTSYGSDLGIGSSSLLIILFVTQVVAAPFSIIYGKLAERFTGKTMLYVGIVIYMIVCVYAYFMETTLDFWILAMLVATSQGGIQALSRSYFAKLVPKRHANEFFGFYNIFGKFASIMGPLLIAVTAQLTGKSSTAVFSLIILFVIGIVILAFVPEETSTDVSQQQNDLPL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	428 (388)
Sequences:	9520 (6881)
Seq/√Len:	349.3

ECOLI - LACY MELB UIDB NUPG ENTS YAGG AMPG YAAU YIHO YICJ RHMT XAPB YIHP MDTM YDJK MHPT EXUT MDTH YIHN YGCS PROP YDJE YDFJ YQCE YAJR XYLE YJJL YEGT GLPT YDEE YDHC YCAD GALP MDTL HSRA ARAE UHPT BCR NANT YJHB GUDP UHPC ARAJ YDIM MDFA MDTD YBJJ MDTG TSGA YHJX YHJE SHIA YDHP GARP SOTB YHHS SETC SETA LPLT YEBQ KGTP YNFM FUCP NEPI DGOT YGAY EMRD SETB YDIN HCAT CYNX FSR NARU NARK YEAN YFCJ EMRB YJIJ EMRY
BACSU - YXIO YXAM YBFB YJMB EXUT YVQJ YQJV CSBC YFIS CSBX YJBB YNAJ YCXA YQGE YVMA YFKF YFMI YCEJ YKUC YOAB YWBF YWTG YHJO YTBD GUDP YITG GUTA ARAE YFHI BBEX NAIP GLCP YYBF YFIG YYCB YNCC YVKA YTTB YWFA YUXJ IOLT YYAJ BMR2 IOLF NARK YWOG YDGK BMR1 YCNB YFKL YYBO GLPT PBUE YDDS MMR YBCL TCRB NASA YUBD YXLH YDEG YWOD YFNC YFMO YDER LMRB BMR3 YHCA YUSP
HALSA - Q9HPD6 O54630 Q9HMR5 Q9HSM8 Q9HS33 Q9HN67 Q9HSK3 Q9HRX5 Q9HMQ8
SULSO - Q97UR4 Q97WS7 Q7LX65 Q97YL8 Q97VT2 Q97U43 Q97VV2 Q97U80 Q97UY7 Q97VU3 Q97Y11 Q97YY8 Q7LX71 Q97U99 Q97U98 Q97WR1 Q97VB7 Q97WT1 Q97V89 Q97ZC9 Q97X92 Q97Y43 Q97XW7 Q97U76 Q97UD8 Q97YH0 Q97Z36 Q980K3 Q97X02 Q97X47 Q97X63 Q97YG2 Q97VB9 Q97VC8 Q97VQ5 Q97WR9 Q97Z07 Q97U91 Q97VD1 Q97UJ4 Q97WP8 Q97UK1 Q97Y15 Q97YI4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
11_S	204_H	3.671	1.00
78_E	84_F	3.555	1.00
325_L	329_I	3.540	1.00
63_I	119_I	3.201	1.00
91_A	120_G	3.051	1.00
300_G	351_K	3.022	1.00
310_I	337_S	2.963	1.00
226_G	230_K	2.926	1.00
51_A	385_Q	2.677	1.00
317_Y	330_L	2.655	1.00
394_V	397_L	2.564	1.00
294_L	298_F	2.461	1.00
393_A	397_L	2.448	1.00
391_S	397_L	2.439	1.00
81_K	134_D	2.395	1.00
93_V	195_G	2.380	1.00
95_S	120_G	2.327	1.00
305_Y	409_A	2.325	1.00
293_K	296_E	2.320	1.00
269_G	272_S	2.319	1.00
67_L	122_S	2.314	1.00
406_V	410_F	2.293	1.00
230_K	234_Q	2.282	1.00
319_Y	395_F	2.279	1.00
80_C	83_K	2.271	1.00
294_L	303_M	2.253	1.00
136_T	144_V	2.246	1.00
71_L	123_G	2.245	1.00
95_S	116_V	2.229	1.00
98_M	113_F	2.224	1.00
75_A	81_K	2.221	1.00
236_R	240_L	2.197	1.00
312_M	398_I	2.192	1.00
52_Y	107_W	2.175	1.00
227_Q	230_K	2.174	1.00
287_F	336_T	2.162	1.00
8_Q	208_R	2.129	1.00
264_S	270_S	2.117	1.00
390_S	394_V	2.055	1.00
108_L	112_L	2.035	1.00
240_L	410_F	2.033	1.00
390_S	397_L	1.981	1.00
71_L	74_I	1.959	1.00
188_F	192_A	1.957	1.00
247_F	403_I	1.956	1.00
199_I	203_K	1.907	1.00
378_L	382_V	1.907	1.00
314_V	337_S	1.898	1.00
314_V	330_L	1.882	1.00
58_A	378_L	1.874	1.00
88_F	123_G	1.871	1.00
324_T	328_W	1.870	1.00
312_M	405_I	1.866	1.00
391_S	394_V	1.863	1.00
13_V	151_L	1.857	1.00
305_Y	405_I	1.855	1.00
299_T	302_T	1.852	1.00
290_I	293_K	1.848	1.00
9_E	140_R	1.842	1.00
95_S	113_F	1.773	1.00
142_N	296_E	1.759	1.00
109_L	113_F	1.742	1.00
71_L	122_S	1.739	1.00
88_F	120_G	1.736	1.00
382_V	386_L	1.728	1.00
293_K	297_R	1.728	1.00
302_T	306_V	1.706	1.00
108_L	111_L	1.700	1.00
137_P	140_R	1.695	1.00
86_G	202_I	1.693	1.00
224_R	227_Q	1.673	1.00
221_S	224_R	1.660	1.00
301_K	305_Y	1.649	1.00
403_I	407_I	1.637	1.00
298_F	303_M	1.636	1.00
223_K	226_G	1.629	1.00
55_Y	382_V	1.614	1.00
224_R	228_T	1.598	1.00
97_A	188_F	1.590	1.00
228_T	232_I	1.570	1.00
88_F	124_A	1.569	1.00
298_F	302_T	1.558	1.00
183_S	187_F	1.541	1.00
97_A	191_A	1.539	1.00
237_A	412_P	1.533	1.00
390_S	393_A	1.507	1.00
67_L	119_I	1.486	1.00
56_T	111_L	1.479	1.00
396_S	400_L	1.454	1.00
181_A	185_L	1.453	1.00
55_Y	59_I	1.453	1.00
68_G	122_S	1.435	1.00
299_T	303_M	1.434	1.00
16_D	20_S	1.416	1.00
9_E	143_L	1.396	1.00
223_K	227_Q	1.386	1.00
136_T	140_R	1.365	1.00
37_S	389_K	1.361	1.00
407_I	410_F	1.357	1.00
261_S	265_D	1.350	1.00
180_S	184_Q	1.335	1.00
33_L	36_K	1.335	1.00
22_Y	117_S	1.332	1.00
307_G	340_G	1.332	1.00
178_S	181_A	1.323	1.00
305_Y	309_V	1.311	1.00
163_S	190_T	1.302	1.00
239_F	243_L	1.296	1.00
107_W	111_L	1.295	1.00
397_L	401_F	1.285	1.00
50_T	385_Q	1.271	1.00
79_G	83_K	1.264	1.00
225_L	228_T	1.262	1.00
323_T	326_D	1.252	1.00
298_F	306_V	1.249	1.00
192_A	196_L	1.243	1.00
54_G	58_A	1.242	1.00
272_S	324_T	1.242	1.00
251_G	401_F	1.239	1.00
391_S	395_F	1.236	1.00
74_I	84_F	1.233	1.00
72_G	359_N	1.224	1.00
165_A	169_L	1.224	1.00
394_V	398_I	1.223	1.00
139_K	296_E	1.222	1.00
141_M	351_K	1.219	1.00
398_I	402_V	1.214	1.00
54_G	381_A	1.213	1.00
357_H	360_E	1.209	1.00
70_I	74_I	1.208	1.00
260_T	264_S	1.206	1.00
279_V	332_M	1.204	1.00
51_A	55_Y	1.203	1.00
200_P	204_H	1.202	1.00
244_A	408_L	1.196	1.00
383_T	387_T	1.193	1.00
391_S	398_I	1.188	1.00
402_V	406_V	1.184	1.00
226_G	229_M	1.183	1.00
76_D	359_N	1.181	1.00
87_F	91_A	1.174	1.00
32_P	35_Y	1.174	1.00
143_L	296_E	1.160	1.00
35_Y	38_A	1.158	1.00
196_L	200_P	1.157	1.00
60_S	118_A	1.151	1.00
141_M	350_A	1.151	1.00
184_Q	188_F	1.150	1.00
82_K	86_G	1.149	1.00
61_T	64_L	1.146	1.00
283_V	332_M	1.146	1.00
33_L	37_S	1.144	1.00
75_A	359_N	1.143	1.00
51_A	54_G	1.141	1.00
82_K	207_Q	1.138	1.00
94_A	98_M	1.132	1.00
32_P	381_A	1.130	1.00
75_A	134_D	1.123	1.00
181_A	184_Q	1.116	1.00
49_S	52_Y	1.116	1.00
68_G	370_K	1.112	1.00
143_L	147_R	1.109	1.00
304_L	408_L	1.105	1.00
397_L	411_V	1.103	1.00
265_D	389_K	1.101	1.00
63_I	67_L	1.097	1.00
243_L	407_I	1.090	1.00
228_T	231_R	1.088	1.00
222_F	225_L	1.086	1.00
37_S	264_S	1.085	1.00
185_L	188_F	1.081	1.00
312_M	402_V	1.072	1.00
30_V	34_F	1.071	1.00
221_S	228_T	1.071	1.00
17_W	155_G	1.071	1.00
395_F	399_I	1.065	1.00
52_Y	111_L	1.063	1.00
195_G	199_I	1.057	1.00
64_L	68_G	1.053	1.00
381_A	385_Q	1.052	1.00
350_A	362_F	1.050	1.00
112_L	116_V	1.050	1.00
309_V	313_I	1.050	1.00
246_F	372_A	1.048	1.00
95_S	117_S	1.036	1.00
89_V	93_V	1.033	1.00
302_T	305_Y	1.032	1.00
83_K	87_F	1.024	1.00
101_F	188_F	1.022	1.00
230_K	233_R	1.020	1.00
131_F	205_V	1.016	1.00
109_L	112_L	1.014	1.00
34_F	39_A	1.013	1.00
20_S	23_S	1.012	1.00
82_K	205_V	1.010	1.00
31_F	34_F	1.010	1.00
97_A	101_F	1.007	1.00
339_G	343_A	1.007	1.00
163_S	186_S	1.005	1.00
17_W	197_F	1.003	1.00
237_A	240_L	0.999	1.00
317_Y	326_D	0.999	1.00
185_L	189_I	0.995	1.00
268_I	272_S	0.994	1.00
11_S	200_P	0.994	1.00
24_I	156_S	0.991	1.00
309_V	405_I	0.987	1.00
36_K	39_A	0.984	1.00
95_S	98_M	0.983	1.00
72_G	76_D	0.982	1.00
258_M	263_G	0.981	1.00
292_G	296_E	0.981	1.00
258_M	261_S	0.977	1.00
279_V	283_V	0.977	1.00
17_W	154_I	0.973	1.00
247_F	400_L	0.969	1.00
291_Y	340_G	0.969	1.00
397_L	400_L	0.962	1.00
241_F	348_Y	0.959	1.00
103_P	106_H	0.957	1.00
357_H	361_F	0.957	1.00
135_V	144_V	0.955	1.00
20_S	24_I	0.954	1.00
219_I	223_K	0.949	1.00
309_V	312_M	0.947	1.00
287_F	290_I	0.947	1.00
325_L	328_W	0.940	1.00
406_V	409_A	0.938	1.00
401_F	404_G	0.937	1.00
145_S	346_R	0.936	1.00
85_F	201_M	0.923	1.00
15_Y	128_Y	0.922	1.00
36_K	40_A	0.921	1.00
35_Y	110_L	0.920	1.00
36_K	53_L	0.920	1.00
146_A	150_G	0.919	1.00
34_F	38_A	0.917	1.00
353_V	358_A	0.915	1.00
13_V	147_R	0.911	1.00
142_N	295_A	0.910	1.00
17_W	21_A	0.909	1.00
90_S	94_A	0.907	1.00
379_L	382_V	0.906	1.00
392_T	397_L	0.906	1.00
152_G	156_S	0.904	1.00
279_V	328_W	0.904	1.00
268_I	271_S	0.901	1.00
393_A	396_S	0.900	1.00
392_T	396_S	0.897	1.00
303_M	306_V	0.896	1.00
59_I	115_T	0.892	1.00
22_Y	25_V	0.890	1.00
55_Y	58_A	0.890	1.00
35_Y	113_F	0.889	1.00
229_M	233_R	0.889	1.00
201_M	205_V	0.884	1.00
257_T	261_S	0.882	1.00
231_R	234_Q	0.879	1.00
220_N	223_K	0.877	1.00
49_S	385_Q	0.877	1.00
202_I	205_V	0.873	1.00
29_A	33_L	0.872	1.00
78_E	83_K	0.868	1.00
182_A	185_L	0.868	1.00
223_K	228_T	0.865	1.00
235_Y	361_F	0.861	1.00
16_D	19_N	0.854	1.00
98_M	109_L	0.853	1.00
111_L	115_T	0.853	1.00
88_F	91_A	0.852	1.00
397_L	404_G	0.850	1.00
280_T	335_A	0.850	1.00
73_T	77_Y	0.849	1.00
218_V	222_F	0.848	1.00
326_D	329_I	0.847	1.00
32_P	53_L	0.845	1.00
233_R	239_F	0.842	1.00
99_L	113_F	0.834	1.00
177_V	180_S	0.834	1.00
9_E	144_V	0.834	1.00
313_I	317_Y	0.830	1.00
328_W	332_M	0.828	1.00
393_A	404_G	0.827	1.00
392_T	395_F	0.827	1.00
133_V	358_A	0.824	1.00
68_G	126_V	0.824	1.00
276_I	331_A	0.823	1.00
58_A	377_P	0.821	1.00
37_S	40_A	0.817	1.00
244_A	407_I	0.815	1.00
11_S	14_L	0.815	1.00
206_H	209_Y	0.811	1.00
398_I	405_I	0.809	1.00
113_F	116_V	0.808	1.00
221_S	225_L	0.807	1.00
71_L	127_F	0.806	1.00
31_F	36_K	0.806	1.00
287_F	339_G	0.805	1.00
58_A	62_F	0.804	1.00
289_I	293_K	0.802	1.00
390_S	398_I	0.799	1.00
187_F	190_T	0.798	1.00
35_Y	40_A	0.797	1.00
75_A	123_G	0.796	1.00
19_N	125_N	0.796	1.00
273_L	277_L	0.795	1.00
237_A	355_K	0.794	1.00
275_I	328_W	0.788	1.00
10_N	14_L	0.788	1.00
97_A	184_Q	0.788	1.00
75_A	127_F	0.786	1.00
65_A	367_I	0.785	1.00
291_Y	343_A	0.783	1.00
29_A	35_Y	0.783	1.00
52_Y	55_Y	0.782	1.00
219_I	222_F	0.777	1.00
400_L	404_G	0.777	1.00
301_K	413_E	0.775	1.00
40_A	49_S	0.775	1.00
139_K	143_L	0.774	1.00
168_L	271_S	0.772	1.00
194_W	198_T	0.771	1.00
304_L	307_G	0.770	1.00
314_V	317_Y	0.768	1.00
19_N	23_S	0.765	1.00
329_I	333_L	0.764	1.00
36_K	261_S	0.764	1.00
249_I	252_V	0.762	1.00
390_S	395_F	0.762	1.00
374_I	378_L	0.759	1.00
203_K	206_H	0.756	1.00
275_I	279_V	0.755	1.00
60_S	63_I	0.754	1.00
20_S	152_G	0.754	1.00
149_F	342_Q	0.752	1.00
128_Y	131_F	0.751	1.00
307_G	310_I	0.751	1.00
395_F	398_I	0.750	1.00
228_T	360_E	0.750	1.00
132_L	362_F	0.749	1.00
308_I	404_G	0.748	1.00
295_A	344_L	0.745	1.00
67_L	71_L	0.744	1.00
282_V	286_P	0.741	1.00
247_F	407_I	0.741	1.00
236_R	239_F	0.738	1.00
248_Y	345_S	0.738	1.00
277_L	281_Q	0.738	1.00
35_Y	39_A	0.737	1.00
366_N	372_A	0.734	1.00
114_Y	118_A	0.734	1.00
16_D	128_Y	0.732	0.99
98_M	101_F	0.732	0.99
33_L	38_A	0.730	0.99
170_A	182_A	0.729	0.99
14_L	197_F	0.729	0.99
34_F	40_A	0.726	0.99
129_D	362_F	0.726	0.99
61_T	377_P	0.725	0.99
125_N	129_D	0.725	0.99
14_L	18_A	0.724	0.99
225_L	229_M	0.722	0.99
192_A	195_G	0.721	0.99
315_C	319_Y	0.721	0.99
165_A	168_L	0.720	0.99
258_M	265_D	0.720	0.99
252_V	341_I	0.719	0.99
133_V	350_A	0.718	0.99
79_G	207_Q	0.714	0.99
223_K	231_R	0.711	0.99
147_R	151_L	0.710	0.99
392_T	398_I	0.709	0.99
104_S	108_L	0.707	0.99
110_L	113_F	0.705	0.99
32_P	40_A	0.705	0.99
222_F	229_M	0.702	0.99
57_I	61_T	0.702	0.99
208_R	211_I	0.700	0.99
245_Y	345_S	0.699	0.99
122_S	125_N	0.696	0.99
348_Y	411_V	0.688	0.99
17_W	20_S	0.688	0.99
142_N	347_S	0.683	0.99
312_M	401_F	0.679	0.99
191_A	195_G	0.679	0.99
307_G	341_I	0.678	0.99
382_V	385_Q	0.678	0.99
197_F	200_P	0.677	0.99
177_V	182_A	0.676	0.99
306_V	309_V	0.676	0.99
241_F	352_L	0.675	0.99
346_R	362_F	0.674	0.99
398_I	401_F	0.674	0.99
23_S	26_V	0.672	0.99
49_S	265_D	0.671	0.99
399_I	403_I	0.670	0.99
391_S	396_S	0.669	0.99
146_A	292_G	0.669	0.99
257_T	260_T	0.668	0.99
249_I	369_G	0.668	0.99
393_A	401_F	0.664	0.99
112_L	115_T	0.664	0.99
90_S	93_V	0.664	0.99
317_Y	320_F	0.662	0.99
321_M	330_L	0.661	0.99
187_F	191_A	0.661	0.99
200_P	203_K	0.661	0.99
92_G	121_F	0.660	0.99
315_C	318_A	0.660	0.99
307_G	311_Y	0.659	0.99
88_F	127_F	0.657	0.99
222_F	228_T	0.657	0.99
286_P	290_I	0.656	0.99
121_F	125_N	0.655	0.99
66_M	70_I	0.655	0.99
101_F	184_Q	0.654	0.99
274_L	278_F	0.650	0.99
29_A	32_P	0.647	0.99
9_E	147_R	0.646	0.99
161_I	278_F	0.645	0.99
161_I	164_I	0.645	0.99
387_T	392_T	0.643	0.99
16_D	148_G	0.643	0.99
341_I	344_L	0.642	0.99
52_Y	56_T	0.641	0.99
120_G	123_G	0.640	0.99
74_I	78_E	0.637	0.99
164_I	168_L	0.635	0.99
18_A	22_Y	0.631	0.98
300_G	347_S	0.628	0.98
308_I	405_I	0.628	0.98
96_T	117_S	0.627	0.98
159_P	163_S	0.627	0.98
177_V	181_A	0.627	0.98
82_K	131_F	0.627	0.98
151_L	155_G	0.626	0.98
235_Y	238_L	0.626	0.98
312_M	315_C	0.624	0.98
164_I	167_I	0.623	0.98
65_A	69_P	0.620	0.98
111_L	114_Y	0.619	0.98
56_T	59_I	0.618	0.98
50_T	53_L	0.618	0.98
21_A	30_V	0.617	0.98
226_G	232_I	0.616	0.98
231_R	235_Y	0.616	0.98
209_Y	212_K	0.616	0.98
262_Y	266_L	0.614	0.98
65_A	370_K	0.614	0.98
409_A	412_P	0.613	0.98
220_N	229_M	0.612	0.98
409_A	413_E	0.611	0.98
245_Y	369_G	0.610	0.98
263_G	276_I	0.609	0.98
182_A	186_S	0.607	0.98
64_L	122_S	0.607	0.98
136_T	141_M	0.603	0.98
189_I	193_W	0.602	0.98
179_V	182_A	0.600	0.98
272_S	275_I	0.600	0.98
330_L	337_S	0.599	0.98
305_Y	308_I	0.599	0.98
84_F	127_F	0.598	0.98
210_Y	214_E	0.597	0.98
54_G	57_I	0.596	0.98
166_V	170_A	0.594	0.98
238_L	361_F	0.593	0.98
319_Y	398_I	0.593	0.98
202_I	207_Q	0.593	0.98
14_L	200_P	0.591	0.98
335_A	345_S	0.587	0.98
394_V	401_F	0.586	0.98
408_L	411_V	0.585	0.98
53_L	57_I	0.581	0.97
251_G	404_G	0.580	0.97
16_D	125_N	0.579	0.97
283_V	287_F	0.578	0.97
314_V	318_A	0.578	0.97
394_V	411_V	0.578	0.97
390_S	404_G	0.578	0.97
84_F	88_F	0.578	0.97
304_L	311_Y	0.577	0.97
259_S	263_G	0.576	0.97
100_A	184_Q	0.575	0.97
106_H	114_Y	0.574	0.97
250_D	376_G	0.574	0.97
186_S	190_T	0.573	0.97
286_P	289_I	0.572	0.97
67_L	70_I	0.572	0.97
391_S	404_G	0.572	0.97
8_Q	11_S	0.570	0.97
272_S	328_W	0.570	0.97
235_Y	352_L	0.567	0.97
307_G	337_S	0.564	0.97
33_L	264_S	0.563	0.97
93_V	97_A	0.561	0.97
224_R	231_R	0.560	0.97
178_S	182_A	0.559	0.97
88_F	92_G	0.558	0.97
16_D	152_G	0.557	0.97
89_V	92_G	0.557	0.97
80_C	207_Q	0.557	0.97
132_L	145_S	0.557	0.97
133_V	145_S	0.556	0.97
57_I	60_S	0.556	0.97
34_F	37_S	0.554	0.97
10_N	13_V	0.553	0.97
272_S	279_V	0.553	0.97
157_T	285_A	0.552	0.97
32_P	36_K	0.552	0.97
64_L	370_K	0.552	0.97
148_G	346_R	0.551	0.96
150_G	289_I	0.550	0.96
148_G	152_G	0.550	0.96
353_V	361_F	0.550	0.96
61_T	68_G	0.549	0.96
63_I	115_T	0.548	0.96
58_A	61_T	0.548	0.96
87_F	123_G	0.547	0.96
14_L	151_L	0.546	0.96
343_A	347_S	0.545	0.96
82_K	206_H	0.543	0.96
194_W	197_F	0.543	0.96
311_Y	315_C	0.543	0.96
222_F	232_I	0.542	0.96
149_F	153_Y	0.541	0.96
241_F	365_Y	0.541	0.96
271_S	275_I	0.541	0.96
18_A	196_L	0.540	0.96
204_H	207_Q	0.540	0.96
147_R	150_G	0.540	0.96
30_V	35_Y	0.539	0.96
89_V	124_A	0.539	0.96
25_V	159_P	0.539	0.96
391_S	399_I	0.538	0.96
85_F	131_F	0.537	0.96
23_S	27_T	0.536	0.96
405_I	409_A	0.535	0.96
153_Y	288_S	0.535	0.96
80_C	134_D	0.534	0.96
92_G	96_T	0.534	0.96
55_Y	385_Q	0.533	0.96
54_G	382_V	0.533	0.96
222_F	227_Q	0.532	0.96
326_D	330_L	0.531	0.96
142_N	292_G	0.531	0.96
229_M	232_I	0.530	0.96
347_S	350_A	0.529	0.96
310_I	314_V	0.528	0.96
50_T	381_A	0.526	0.95
295_A	347_S	0.524	0.95
129_D	153_Y	0.523	0.95
19_N	198_T	0.523	0.95
128_Y	148_G	0.523	0.95
393_A	405_I	0.523	0.95
312_M	316_V	0.523	0.95
300_G	344_L	0.522	0.95
240_L	412_P	0.522	0.95
314_V	333_L	0.521	0.95
253_G	257_T	0.520	0.95
58_A	382_V	0.519	0.95
303_M	344_L	0.517	0.95
61_T	118_A	0.515	0.95
68_G	125_N	0.512	0.95
102_I	109_L	0.512	0.95
130_A	133_V	0.511	0.95
396_S	404_G	0.511	0.95
30_V	40_A	0.511	0.95
350_A	354_P	0.509	0.95
156_S	160_F	0.508	0.95
106_H	109_L	0.507	0.94
59_I	63_I	0.504	0.94
95_S	99_L	0.503	0.94
106_H	110_L	0.503	0.94
252_V	342_Q	0.503	0.94
291_Y	339_G	0.503	0.94
336_T	340_G	0.503	0.94
30_V	33_L	0.502	0.94
397_L	408_L	0.502	0.94
102_I	110_L	0.501	0.94
186_S	189_I	0.500	0.94
18_A	197_F	0.500	0.94

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4m64A	1	0.965	100	0.399	Contact Map
2cfqA	1	0.9439	100	0.424	Contact Map
3wdoA	1	0.9299	100	0.435	Contact Map
1pw4A	1	0.9276	100	0.444	Contact Map
4j05A	3	0.9089	100	0.463	Contact Map
3o7qA	1	0.9182	100	0.478	Contact Map
4w6vA	1	0.9042	100	0.481	Contact Map
4pypA	1	0.9136	100	0.489	Contact Map
2gfpA	2	0.8668	100	0.495	Contact Map
4xnjA	1	0.9042	100	0.495	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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