GREMLIN Database
YCBJ - Uncharacterized protein YcbJ
UniProt: P42242 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 306 (271)
Sequences: 5507 (4158)
Seq/√Len: 252.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
85_D97_P3.9511.00
80_T137_E3.8831.00
133_D254_Y3.8431.00
99_L220_G3.6241.00
72_L86_W3.3751.00
42_F98_M3.2461.00
50_P98_M3.0351.00
131_L210_I2.9961.00
130_T133_D2.9531.00
42_F50_P2.9141.00
53_L95_A2.8851.00
14_V18_R2.8451.00
187_W191_D2.8141.00
129_R254_Y2.7731.00
69_G86_W2.7661.00
139_H255_Y2.7121.00
44_K50_P2.6541.00
134_I221_L2.6501.00
76_R85_D2.6041.00
99_L219_T2.5721.00
125_D250_R2.4971.00
28_N44_K2.4831.00
119_D123_P2.4771.00
133_D258_A2.4621.00
132_A254_Y2.3611.00
125_D129_R2.3091.00
160_R164_A2.3061.00
103_P211_L2.2571.00
213_D217_R2.2231.00
30_Q42_F2.0311.00
239_Y251_L1.8971.00
247_E250_R1.8951.00
144_I149_S1.8911.00
132_A251_L1.8891.00
130_T217_R1.8761.00
201_I230_A1.8241.00
211_L219_T1.7981.00
287_Q291_E1.7621.00
186_K190_D1.7601.00
252_L267_Q1.7431.00
137_E258_A1.7371.00
253_E257_Q1.7301.00
199_S232_P1.7101.00
99_L211_L1.7081.00
12_E15_G1.7011.00
263_W266_M1.6301.00
211_L222_L1.6281.00
50_P100_K1.6271.00
72_L84_P1.5971.00
141_T146_A1.5951.00
135_L205_L1.5571.00
100_K213_D1.5221.00
140_G259_G1.5121.00
130_T134_I1.5101.00
76_R86_W1.5101.00
167_M171_K1.5101.00
168_V172_N1.5051.00
159_F162_M1.5031.00
164_A168_V1.4641.00
130_T218_V1.4581.00
37_D225_T1.4441.00
30_Q44_K1.4251.00
163_T167_M1.4221.00
71_T227_A1.4111.00
249_A253_E1.4041.00
11_T14_V1.3891.00
134_I218_V1.3751.00
254_Y257_Q1.3631.00
10_I29_A1.3531.00
180_L183_R1.3451.00
42_F52_V1.3381.00
55_K91_P1.3361.00
237_V274_Q1.3311.00
286_L290_Q1.3101.00
213_D219_T1.3051.00
204_D209_H1.3031.00
129_R250_R1.3011.00
143_Q200_L1.2951.00
167_M189_D1.2721.00
52_V98_M1.2661.00
133_D137_E1.2461.00
38_F54_R1.2411.00
158_D162_M1.2411.00
142_D145_S1.2341.00
100_K214_Q1.2291.00
66_S70_I1.2201.00
69_G73_A1.2151.00
187_W272_E1.2131.00
166_S170_V1.1911.00
254_Y258_A1.1791.00
167_M185_Q1.1771.00
240_Q267_Q1.1691.00
104_A127_F1.1621.00
162_M166_S1.1471.00
119_D122_P1.1451.00
171_K174_L1.1371.00
105_A208_P1.1281.00
197_F261_R1.1141.00
70_I74_F1.1121.00
131_L205_L1.1061.00
10_I14_V1.0991.00
73_A86_W1.0971.00
128_V246_K1.0871.00
134_I137_E1.0861.00
164_A189_D1.0831.00
131_L239_Y1.0831.00
205_L221_L1.0831.00
168_V171_K1.0811.00
102_T123_P1.0671.00
174_L177_S1.0671.00
269_H273_M1.0461.00
230_A235_D1.0451.00
37_D40_V1.0381.00
17_A95_A1.0381.00
273_M277_Y1.0331.00
138_L221_L1.0271.00
163_T166_S1.0251.00
138_L200_L1.0241.00
43_A95_A1.0231.00
132_A258_A1.0211.00
285_A289_Q1.0201.00
70_I73_A1.0101.00
286_L289_Q0.9991.00
49_M97_P0.9971.00
171_K182_E0.9961.00
97_P220_G0.9911.00
129_R133_D0.9901.00
71_T200_L0.9831.00
165_D169_D0.9801.00
198_S229_V0.9791.00
143_Q149_S0.9771.00
127_F212_I0.9751.00
201_I228_K0.9751.00
185_Q189_D0.9731.00
17_A21_G0.9611.00
250_R253_E0.9431.00
136_A256_D0.9351.00
146_A149_S0.9341.00
126_D129_R0.9341.00
184_W187_W0.9341.00
84_P96_Y0.9341.00
236_F252_L0.9321.00
209_H223_D0.9301.00
123_P126_D0.9261.00
123_P216_G0.9241.00
129_R258_A0.9141.00
132_A136_A0.9131.00
51_W87_R0.9081.00
81_A134_I0.9071.00
162_M169_D0.9051.00
195_P231_D0.9031.00
252_L256_D0.8891.00
143_Q229_V0.8891.00
35_G223_D0.8871.00
40_V222_L0.8861.00
15_G18_R0.8791.00
14_V26_S0.8771.00
147_G150_G0.8751.00
72_L94_I0.8711.00
69_G94_I0.8711.00
185_Q188_V0.8691.00
155_R158_D0.8681.00
63_E66_S0.8671.00
82_D134_I0.8671.00
90_T93_L0.8671.00
43_A53_L0.8661.00
16_L93_L0.8650.99
135_L139_H0.8580.99
54_R224_W0.8540.99
248_T252_L0.8480.99
87_R92_E0.8460.99
282_A285_A0.8430.99
156_P160_R0.8430.99
76_R83_V0.8420.99
183_R187_W0.8360.99
133_D136_A0.8360.99
281_I285_A0.8340.99
265_K268_E0.8300.99
136_A259_G0.8290.99
176_V283_K0.8270.99
285_A288_T0.8250.99
170_V173_K0.8240.99
156_P159_F0.8200.99
240_Q271_S0.8190.99
169_D173_K0.8130.99
18_R25_H0.8130.99
266_M269_H0.8130.99
74_F146_A0.8090.99
143_Q146_A0.8060.99
21_G24_V0.8050.99
213_D216_G0.8050.99
183_R186_K0.8050.99
35_G209_H0.8030.99
250_R254_Y0.8020.99
278_P281_I0.7990.99
73_A77_A0.7980.99
70_I150_G0.7970.99
134_I205_L0.7900.99
228_K234_K0.7880.99
73_A76_R0.7870.99
135_L235_D0.7870.99
102_T214_Q0.7860.99
287_Q290_Q0.7830.99
164_A167_M0.7820.99
181_W185_Q0.7770.99
210_I221_L0.7760.99
11_T15_G0.7730.99
167_M170_V0.7700.99
152_E155_R0.7700.99
166_S169_D0.7670.99
202_H224_W0.7660.99
68_E72_L0.7660.99
147_G152_E0.7640.99
182_E185_Q0.7630.99
77_A80_T0.7630.99
131_L135_L0.7600.99
182_E186_K0.7590.99
24_V51_W0.7580.99
32_N52_V0.7520.99
153_V157_E0.7500.99
167_M174_L0.7480.99
185_Q276_A0.7470.99
241_T274_Q0.7410.98
256_D264_A0.7400.98
284_L288_T0.7380.98
186_K189_D0.7310.98
206_H226_E0.7280.98
27_E43_A0.7240.98
160_R192_A0.7230.98
163_T170_V0.7210.98
74_F77_A0.7210.98
128_V245_E0.7190.98
40_V206_H0.7190.98
210_I218_V0.7190.98
167_M172_N0.7170.98
79_L82_D0.7170.98
100_K219_T0.7170.98
46_D51_W0.7150.98
281_I284_L0.7150.98
38_F56_P0.7130.98
104_A212_I0.7120.98
157_E160_R0.7080.98
201_I234_K0.7000.98
166_S173_K0.7000.98
171_K185_Q0.6980.98
158_D166_S0.6970.98
268_E271_S0.6970.98
126_D217_R0.6950.98
129_R132_A0.6910.98
52_V96_Y0.6900.98
37_D57_R0.6900.98
264_A267_Q0.6860.97
54_R68_E0.6830.97
102_T106_G0.6820.97
71_T224_W0.6810.97
248_T271_S0.6790.97
102_T213_D0.6790.97
267_Q271_S0.6790.97
103_P222_L0.6780.97
44_K48_G0.6720.97
283_K286_L0.6710.97
17_A51_W0.6690.97
191_D269_H0.6670.97
36_M206_H0.6670.97
87_R90_T0.6630.97
44_K47_T0.6600.97
181_W280_E0.6590.97
153_V156_P0.6580.97
65_A94_I0.6580.97
117_N120_H0.6570.97
81_A141_T0.6570.97
236_F239_Y0.6560.97
272_E275_A0.6550.97
234_K237_V0.6550.97
276_A280_E0.6540.97
127_F130_T0.6540.97
74_F141_T0.6540.97
226_E281_I0.6530.97
204_D223_D0.6520.97
205_L210_I0.6520.97
126_D130_T0.6470.96
239_Y243_F0.6470.96
253_E256_D0.6470.96
156_P164_A0.6460.96
118_M123_P0.6460.96
37_D226_E0.6450.96
261_R264_A0.6450.96
32_N42_F0.6440.96
163_T174_L0.6420.96
81_A138_L0.6400.96
56_P65_A0.6380.96
178_T182_E0.6370.96
139_H201_I0.6370.96
15_G19_S0.6360.96
179_T183_R0.6360.96
37_D64_R0.6360.96
271_S275_A0.6320.96
269_H272_E0.6310.96
27_E47_T0.6300.96
81_A86_W0.6290.96
103_P106_G0.6270.96
189_D192_A0.6250.96
270_I274_Q0.6240.96
122_P125_D0.6200.95
61_V64_R0.6150.95
20_Q25_H0.6130.95
177_S182_E0.6130.95
151_I227_A0.6120.95
202_H235_D0.6110.95
277_Y280_E0.6110.95
175_G283_K0.6100.95
126_D215_N0.6100.95
27_E46_D0.6090.95
136_A258_A0.6090.95
285_A290_Q0.6080.95
38_F209_H0.6050.95
257_Q260_G0.6040.95
28_N43_A0.6040.95
64_R226_E0.6030.95
18_R23_T0.6030.95
129_R246_K0.6000.95
169_D172_N0.5980.94
57_R226_E0.5980.94
66_S92_E0.5970.94
12_E17_A0.5970.94
139_H235_D0.5970.94
236_F251_L0.5950.94
285_A291_E0.5900.94
25_H46_D0.5880.94
152_E157_E0.5880.94
202_H205_L0.5870.94
129_R257_Q0.5840.94
181_W184_W0.5830.94
83_V86_W0.5800.93
155_R162_M0.5790.93
170_V174_L0.5770.93
128_V132_A0.5770.93
57_R206_H0.5750.93
209_H220_G0.5750.93
79_L141_T0.5730.93
102_T117_N0.5730.93
233_A266_M0.5700.93
156_P163_T0.5690.93
67_A71_T0.5670.93
240_Q243_F0.5660.93
238_L242_I0.5630.92
177_S184_W0.5620.92
38_F41_V0.5610.92
35_G52_V0.5610.92
240_Q248_T0.5610.92
67_A148_Q0.5610.92
118_M127_F0.5600.92
31_L41_V0.5590.92
203_G235_D0.5590.92
46_D49_M0.5580.92
165_D168_V0.5560.92
56_P66_S0.5540.92
158_D161_Q0.5530.92
178_T185_Q0.5530.92
237_V271_S0.5510.92
22_L25_H0.5510.92
61_V65_A0.5490.92
208_P238_L0.5480.91
137_E140_G0.5470.91
159_F167_M0.5470.91
29_A43_A0.5470.91
136_A254_Y0.5470.91
170_V175_G0.5460.91
142_D147_G0.5460.91
231_D270_I0.5440.91
196_G231_D0.5420.91
142_D229_V0.5410.91
126_D133_D0.5400.91
176_V179_T0.5390.91
277_Y284_L0.5370.91
75_L224_W0.5370.91
40_V57_R0.5350.90
146_A150_G0.5350.90
231_D236_F0.5350.90
163_T171_K0.5340.90
106_G109_L0.5340.90
64_R225_T0.5330.90
160_R163_T0.5320.90
277_Y281_I0.5320.90
75_L79_L0.5290.90
161_Q165_D0.5280.90
131_L251_L0.5260.90
181_W187_W0.5210.89
208_P211_L0.5210.89
136_A255_Y0.5200.89
177_S180_L0.5180.89
134_I138_L0.5180.89
160_R217_R0.5110.88
184_W188_V0.5110.88
159_F273_M0.5100.88
220_G238_L0.5080.88
158_D164_A0.5070.88
143_Q198_S0.5070.88
139_H199_S0.5060.88
197_F259_G0.5060.88
272_E278_P0.5060.88
14_V24_V0.5030.88
231_D269_H0.5020.87
266_M270_I0.5020.87
159_F163_T0.5000.87
147_G151_I0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3tdwA 1 0.9183 100 0.376 Contact Map
3dxpA 2 0.9248 100 0.388 Contact Map
4orkA 1 0.9281 100 0.396 Contact Map
4dcaA 1 0.9052 100 0.419 Contact Map
3atsA 1 0.9575 100 0.421 Contact Map
3sg8A 2 0.9314 100 0.435 Contact Map
3w0oA 1 0.8431 100 0.461 Contact Map
3jr1A 1 0.8987 100 0.479 Contact Map
3csvA 2 0.8889 100 0.481 Contact Map
3f7wA 1 0.8791 100 0.484 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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