GARD - BACSU - GREMLIN Contacts

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GARD - Probable D-galactarate dehydratase

UniProt:	P42240	Sequences: MAMNLRKNQAPLYIKVHEIDNTAIIVNDGGLPKGTVFSCGLVLEEDVPQGHKVALTDLNQGDEIVRYGEVIGFADETIKRGSWIREALVRMPAPPALDDLPLANRVPQPRPPLEGYTFEGYRNADGSAGTKNILGITTSVQCVVGVLDYAVKRIKEELLPKYPNVDDVVPLHHQYGCGVAINAPDAVIPIRTIQNLAKHPNFGGEVMVIGLGCEKLLPERIASENDDDILSLQDHRGFAAMIQSILEMAEERLIRLNSRTRVSCPVSDLVIGLQCGGSDAFSGVTANPAVGYAADLLVRAGATVLFSEVTEVRDAIHLLTPRAVSEEVGQSLIKEMKWYDSYLRRGDADRSANPSPGNKKGGLSNVVEKALGSVAKSGTSPISGVLGPGERAKQKGLLFAATPASDFVCGTLQLAAGMNLQVFTTGRGTPYGLAAAPVLKVSTRHSLSEHWADLIDINAGRIATGEASIEDVGWEIFRTILDVASGRKQTWADRWGLHNDLCLFNPAPVT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	510 (487)
Sequences:	1207 (775)
Seq/√Len:	35.1

ECOLI - GARD UXAA
BACSU - GARD UXAA
SULSO - Q97YR2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
482_D	487_R	6.533	1.00
119_E	263_S	5.122	1.00
122_R	268_D	4.982	1.00
266_V	481_L	4.139	1.00
122_R	262_V	3.876	1.00
74_A	78_I	3.853	1.00
31_L	43_L	3.853	1.00
325_S	328_V	3.846	1.00
294_A	304_V	3.799	1.00
326_E	330_Q	3.735	1.00
122_R	264_C	3.579	1.00
23_A	55_L	3.523	1.00
57_D	80_R	3.360	1.00
305_L	418_M	3.341	1.00
290_V	424_T	3.271	1.00
268_D	395_K	3.259	1.00
402_T	416_A	3.151	1.00
45_E	82_S	3.053	1.00
445_H	449_E	2.977	1.00
491_W	494_R	2.969	1.00
457_I	476_I	2.934	1.00
458_N	464_T	2.933	1.00
59_N	62_D	2.892	1.00
60_Q	77_T	2.776	1.00
59_N	77_T	2.721	1.00
330_Q	334_K	2.712	1.00
43_L	53_V	2.678	1.00
128_A	264_C	2.662	1.00
442_S	455_I	2.598	1.00
12_L	27_N	2.594	1.00
64_I	89_V	2.586	1.00
303_T	398_L	2.560	1.00
57_D	79_K	2.543	1.00
116_Y	478_R	2.535	1.00
54_A	78_I	2.513	1.00
203_G	256_L	2.468	1.00
33_K	46_D	2.455	1.00
164_N	257_N	2.402	1.00
341_S	345_R	2.400	1.00
121_Y	129_G	2.390	1.00
79_K	82_S	2.362	0.99
458_N	461_R	2.291	0.99
264_C	268_D	2.290	0.99
58_L	74_A	2.226	0.99
58_L	78_I	2.223	0.99
420_L	480_I	2.209	0.99
478_R	482_D	2.188	0.99
27_N	35_T	2.184	0.99
422_V	441_V	2.166	0.99
73_F	92_P	2.165	0.99
154_I	246_L	2.153	0.99
461_R	475_E	2.121	0.99
25_I	31_L	2.110	0.99
439_L	483_V	2.109	0.99
289_A	476_I	2.098	0.99
441_V	459_A	2.053	0.99
21_N	58_L	2.037	0.98
479_T	487_R	1.998	0.98
116_Y	481_L	1.993	0.98
15_K	39_C	1.987	0.98
289_A	462_I	1.971	0.98
131_K	493_D	1.971	0.98
244_S	247_E	1.960	0.98
32_P	46_D	1.956	0.98
462_I	469_I	1.945	0.98
147_L	209_I	1.931	0.98
58_L	62_D	1.913	0.98
150_A	245_I	1.896	0.98
119_E	487_R	1.893	0.97
337_K	340_D	1.890	0.97
271_I	293_A	1.872	0.97
43_L	47_V	1.858	0.97
135_G	202_F	1.851	0.97
445_H	458_N	1.847	0.97
479_T	482_D	1.843	0.97
446_S	450_H	1.835	0.97
255_R	258_S	1.814	0.97
57_D	77_T	1.807	0.97
31_L	53_V	1.771	0.96
433_L	438_V	1.769	0.96
383_S	394_Q	1.765	0.96
324_V	383_S	1.765	0.96
414_L	433_L	1.757	0.96
44_E	79_K	1.749	0.96
21_N	56_T	1.735	0.96
204_G	252_R	1.729	0.96
150_A	242_I	1.717	0.96
296_L	474_W	1.711	0.95
13_Y	23_A	1.710	0.95
384_G	394_Q	1.708	0.95
479_T	483_V	1.706	0.95
407_F	431_Y	1.705	0.95
255_R	259_R	1.704	0.95
331_S	384_G	1.703	0.95
468_S	471_D	1.703	0.95
197_A	221_I	1.697	0.95
472_V	475_E	1.691	0.95
446_S	449_E	1.667	0.95
461_R	472_V	1.662	0.95
134_L	249_A	1.633	0.94
457_I	479_T	1.621	0.94
448_S	455_I	1.615	0.94
296_L	473_G	1.597	0.93
130_T	419_N	1.596	0.93
32_P	35_T	1.584	0.93
178_G	215_K	1.581	0.93
331_S	390_E	1.579	0.93
324_V	328_V	1.577	0.93
138_T	147_L	1.547	0.92
274_Q	413_Q	1.540	0.92
56_T	62_D	1.536	0.92
324_V	394_Q	1.535	0.92
442_S	448_S	1.535	0.92
297_L	302_A	1.533	0.92
292_Y	470_E	1.502	0.91
69_E	318_L	1.500	0.91
116_Y	266_V	1.479	0.90
293_A	297_L	1.472	0.90
76_E	82_S	1.470	0.90
439_L	479_T	1.467	0.90
414_L	436_A	1.438	0.89
323_A	332_L	1.430	0.89
307_S	413_Q	1.420	0.88
197_A	208_V	1.413	0.88
28_D	49_Q	1.407	0.88
12_L	35_T	1.402	0.88
292_Y	469_I	1.399	0.88
44_E	82_S	1.398	0.88
152_K	155_K	1.395	0.88
300_A	477_F	1.382	0.87
134_L	256_L	1.379	0.87
89_V	364_S	1.379	0.87
449_E	452_A	1.379	0.87
247_E	251_E	1.378	0.87
21_N	65_V	1.365	0.86
154_I	168_V	1.360	0.86
49_Q	446_S	1.353	0.86
272_G	421_Q	1.340	0.85
289_A	473_G	1.334	0.85
265_P	268_D	1.332	0.85
24_I	66_R	1.331	0.85
23_A	53_V	1.330	0.85
253_L	257_N	1.326	0.85
328_V	384_G	1.317	0.84
117_T	263_S	1.313	0.84
474_W	478_R	1.285	0.83
190_I	216_L	1.277	0.82
28_D	46_D	1.271	0.82
178_G	356_P	1.270	0.82
124_A	226_D	1.264	0.82
430_P	497_L	1.264	0.82
127_S	391_R	1.264	0.82
387_G	390_E	1.259	0.81
380_S	383_S	1.257	0.81
305_L	392_A	1.240	0.80
127_S	270_V	1.235	0.80
386_L	398_L	1.228	0.80
461_R	466_E	1.227	0.80
332_L	399_F	1.224	0.80
289_A	457_I	1.224	0.80
296_L	477_F	1.223	0.80
324_V	381_P	1.220	0.79
116_Y	477_F	1.219	0.79
75_D	90_R	1.216	0.79
121_Y	259_R	1.204	0.78
153_R	246_L	1.204	0.78
273_L	306_F	1.184	0.77
452_A	491_W	1.183	0.77
122_R	128_A	1.178	0.77
198_K	391_R	1.176	0.77
86_E	368_E	1.174	0.77
257_N	260_T	1.165	0.76
366_V	373_S	1.160	0.76
315_A	374_V	1.156	0.76
119_E	122_R	1.156	0.76
443_T	462_I	1.154	0.75
416_A	443_T	1.149	0.75
133_I	167_D	1.138	0.74
15_K	23_A	1.135	0.74
235_H	241_M	1.135	0.74
150_A	209_I	1.134	0.74
274_Q	410_G	1.131	0.74
45_E	83_W	1.126	0.74
54_A	58_L	1.122	0.73
152_K	156_E	1.119	0.73
85_R	364_S	1.113	0.73
263_S	481_L	1.101	0.72
118_F	128_A	1.100	0.72
150_A	249_A	1.098	0.72
402_T	412_L	1.093	0.71
448_S	452_A	1.091	0.71
244_S	248_M	1.090	0.71
315_A	371_L	1.089	0.71
36_V	42_V	1.089	0.71
341_S	344_R	1.083	0.71
271_I	480_I	1.073	0.70
12_L	26_V	1.067	0.69
63_E	70_V	1.065	0.69
462_I	472_V	1.064	0.69
318_L	371_L	1.063	0.69
273_L	290_V	1.058	0.69
142_C	213_C	1.054	0.69
445_H	460_G	1.053	0.68
60_Q	76_E	1.050	0.68
448_S	458_N	1.050	0.68
78_I	84_I	1.044	0.68
190_I	224_E	1.036	0.67
290_V	441_V	1.035	0.67
220_R	223_S	1.033	0.67
174_Q	502_C	1.027	0.66
116_Y	300_A	1.026	0.66
411_T	501_L	1.024	0.66
473_G	476_I	1.022	0.66
164_N	260_T	1.021	0.66
63_E	92_P	1.020	0.66
150_A	246_L	1.018	0.66
28_D	32_P	1.016	0.66
418_M	435_A	1.016	0.66
154_I	253_L	1.013	0.65
192_T	195_N	1.008	0.65
445_H	464_T	1.000	0.64
197_A	230_L	0.993	0.64
114_E	474_W	0.991	0.64
35_T	43_L	0.990	0.64
274_Q	307_S	0.987	0.63
142_C	177_C	0.983	0.63
63_E	73_F	0.983	0.63
177_C	213_C	0.982	0.63
374_V	409_C	0.980	0.63
148_D	172_H	0.980	0.63
239_A	453_D	0.979	0.63
15_K	55_L	0.979	0.63
91_M	349_D	0.976	0.62
155_K	167_D	0.973	0.62
478_R	481_L	0.958	0.61
248_M	251_E	0.956	0.61
410_G	433_L	0.956	0.61
422_V	480_I	0.954	0.61
28_D	48_P	0.952	0.60
119_E	264_C	0.952	0.60
196_L	435_A	0.947	0.60
164_N	253_L	0.942	0.60
69_E	371_L	0.941	0.60
320_T	333_I	0.940	0.60
122_R	395_K	0.933	0.59
180_A	215_K	0.928	0.59
134_L	151_V	0.928	0.59
327_E	331_S	0.927	0.58
240_A	243_Q	0.922	0.58
293_A	476_I	0.919	0.58
260_T	458_N	0.917	0.58
136_I	151_V	0.916	0.58
162_Y	257_N	0.914	0.57
43_L	46_D	0.913	0.57
165_V	257_N	0.911	0.57
13_Y	43_L	0.910	0.57
445_H	448_S	0.909	0.57
285_T	463_A	0.908	0.57
281_F	463_A	0.905	0.57
245_I	500_D	0.902	0.56
348_A	351_S	0.900	0.56
130_T	420_L	0.892	0.55
137_T	197_A	0.892	0.55
320_T	336_M	0.891	0.55
488_K	494_R	0.891	0.55
127_S	268_D	0.890	0.55
270_V	395_K	0.886	0.55
384_G	393_K	0.884	0.55
199_H	419_N	0.882	0.55
169_V	498_H	0.878	0.54
262_V	268_D	0.874	0.54
466_E	475_E	0.871	0.54
64_I	73_F	0.871	0.54
490_T	493_D	0.870	0.54
272_G	294_A	0.868	0.53
84_I	89_V	0.865	0.53
338_W	401_A	0.865	0.53
243_Q	247_E	0.863	0.53
313_R	340_D	0.860	0.53
293_A	304_V	0.858	0.53
330_Q	337_K	0.850	0.52
188_I	506_P	0.842	0.51
59_N	79_K	0.840	0.51
139_S	210_G	0.839	0.51
326_E	329_G	0.838	0.51
119_E	260_T	0.837	0.51
343_L	451_W	0.837	0.51
266_V	477_F	0.837	0.51
410_G	431_Y	0.836	0.51
392_A	398_L	0.829	0.50
303_T	384_G	0.828	0.50
292_Y	379_T	0.826	0.50
441_V	457_I	0.826	0.50
215_K	356_P	0.824	0.50
273_L	380_S	0.822	0.49
215_K	348_A	0.820	0.49
134_L	204_G	0.820	0.49
18_E	58_L	0.817	0.49
69_E	317_H	0.814	0.49
127_S	395_K	0.814	0.49
91_M	354_P	0.811	0.49
355_S	443_T	0.809	0.48
118_F	484_A	0.809	0.48
33_K	43_L	0.808	0.48
18_E	125_D	0.807	0.48
439_L	490_T	0.806	0.48
95_P	350_R	0.806	0.48
469_I	473_G	0.805	0.48
153_R	157_E	0.804	0.48
218_P	222_A	0.803	0.48
355_S	366_V	0.802	0.48
343_L	350_R	0.801	0.48
146_V	238_F	0.797	0.47
325_S	478_R	0.796	0.47
386_L	416_A	0.795	0.47
439_L	480_I	0.795	0.47
315_A	354_P	0.793	0.47
13_Y	53_V	0.792	0.47
289_A	472_V	0.792	0.47
414_L	421_Q	0.790	0.47
363_L	374_V	0.789	0.47
86_E	89_V	0.788	0.47
145_G	148_D	0.785	0.46
271_I	420_L	0.785	0.46
387_G	401_A	0.784	0.46
53_V	56_T	0.784	0.46
101_P	321_P	0.784	0.46
47_V	128_A	0.784	0.46
476_I	479_T	0.783	0.46
269_L	484_A	0.781	0.46
135_G	329_G	0.779	0.46
54_A	74_A	0.778	0.46
203_G	259_R	0.775	0.45
56_T	204_G	0.773	0.45
102_L	329_G	0.770	0.45
118_F	264_C	0.766	0.45
391_R	416_A	0.765	0.45
19_I	68_G	0.761	0.44
45_E	53_V	0.761	0.44
310_T	350_R	0.760	0.44
449_E	458_N	0.759	0.44
491_W	495_W	0.757	0.44
86_E	364_S	0.757	0.44
27_N	31_L	0.750	0.43
163_P	257_N	0.747	0.43
210_G	218_P	0.747	0.43
412_L	503_L	0.747	0.43
70_V	458_N	0.746	0.43
389_G	416_A	0.744	0.43
431_Y	438_V	0.744	0.43
102_L	333_I	0.739	0.42
190_I	377_S	0.739	0.42
56_T	59_N	0.736	0.42
285_T	465_G	0.736	0.42
263_S	266_V	0.736	0.42
303_T	402_T	0.734	0.42
317_H	321_P	0.733	0.42
361_G	427_R	0.733	0.42
192_T	415_A	0.731	0.42
217_L	402_T	0.729	0.42
272_G	434_A	0.727	0.41
307_S	402_T	0.727	0.41
290_V	476_I	0.726	0.41
294_A	380_S	0.725	0.41
142_C	211_L	0.725	0.41
129_G	259_R	0.724	0.41
32_P	43_L	0.723	0.41
157_E	250_E	0.723	0.41
334_K	338_W	0.722	0.41
98_D	333_I	0.721	0.41
47_V	111_P	0.720	0.41
146_V	242_I	0.718	0.41
492_A	495_W	0.717	0.41
290_V	392_A	0.717	0.41
64_I	74_A	0.715	0.40
303_T	392_A	0.715	0.40
386_L	392_A	0.712	0.40
264_C	419_N	0.711	0.40
199_H	502_C	0.711	0.40
384_G	398_L	0.710	0.40
199_H	420_L	0.710	0.40
116_Y	296_L	0.708	0.40
329_G	366_V	0.707	0.40
249_A	253_L	0.707	0.40
293_A	480_I	0.706	0.40
194_Q	198_K	0.703	0.39
32_P	55_L	0.701	0.39
177_C	211_L	0.701	0.39
154_I	158_L	0.700	0.39
47_V	53_V	0.700	0.39
33_K	59_N	0.700	0.39
203_G	208_V	0.700	0.39
185_D	508_P	0.699	0.39
138_T	170_P	0.699	0.39
478_R	487_R	0.699	0.39
273_L	443_T	0.698	0.39
459_A	472_V	0.698	0.39
64_I	76_E	0.698	0.39
49_Q	281_F	0.694	0.39
414_L	438_V	0.694	0.39
54_A	89_V	0.691	0.38
296_L	299_R	0.691	0.38
228_D	251_E	0.690	0.38
298_V	383_S	0.689	0.38
35_T	325_S	0.689	0.38
57_D	325_S	0.689	0.38
238_F	242_I	0.688	0.38
302_A	420_L	0.688	0.38
256_L	259_R	0.688	0.38
70_V	73_F	0.686	0.38
26_V	200_P	0.685	0.38
162_Y	253_L	0.685	0.38
305_L	413_Q	0.684	0.38
27_N	32_P	0.682	0.38
85_R	88_L	0.682	0.38
441_V	476_I	0.681	0.38
210_G	371_L	0.681	0.38
62_D	74_A	0.679	0.37
45_E	76_E	0.678	0.37
118_F	269_L	0.677	0.37
50_G	139_S	0.676	0.37
129_G	200_P	0.675	0.37
293_A	473_G	0.675	0.37
125_D	419_N	0.673	0.37
73_F	94_P	0.672	0.37
118_F	485_S	0.670	0.37
111_P	115_G	0.667	0.37
15_K	57_D	0.666	0.36
115_G	265_P	0.663	0.36
267_S	481_L	0.661	0.36
180_A	349_D	0.660	0.36
442_S	445_H	0.658	0.36
56_T	60_Q	0.658	0.36
151_V	155_K	0.657	0.36
89_V	105_R	0.655	0.36
64_I	78_I	0.653	0.35
117_T	265_P	0.653	0.35
305_L	400_A	0.652	0.35
331_S	334_K	0.651	0.35
410_G	421_Q	0.651	0.35
120_G	264_C	0.650	0.35
405_S	508_P	0.650	0.35
62_D	389_G	0.649	0.35
443_T	463_A	0.646	0.35
315_A	318_L	0.643	0.35
161_K	250_E	0.641	0.34
323_A	328_V	0.640	0.34
309_V	373_S	0.640	0.34
462_I	473_G	0.639	0.34
192_T	389_G	0.639	0.34
31_L	209_I	0.637	0.34
392_A	444_R	0.634	0.34
289_A	293_A	0.634	0.34
447_L	452_A	0.634	0.34
18_E	21_N	0.633	0.34
58_L	80_R	0.632	0.34
179_V	215_K	0.631	0.34
271_I	390_E	0.631	0.34
374_V	421_Q	0.630	0.34
354_P	366_V	0.629	0.34
39_C	55_L	0.628	0.33
14_I	26_V	0.627	0.33
77_T	448_S	0.626	0.33
447_L	455_I	0.625	0.33
14_I	281_F	0.625	0.33
402_T	408_V	0.625	0.33
363_L	453_D	0.624	0.33
78_I	370_A	0.623	0.33
368_E	432_G	0.623	0.33
258_S	326_E	0.623	0.33
273_L	304_V	0.623	0.33
194_Q	224_E	0.622	0.33
91_M	367_V	0.621	0.33
24_I	53_V	0.620	0.33
265_P	449_E	0.619	0.33
174_Q	408_V	0.619	0.33
209_I	233_Q	0.619	0.33
103_A	107_P	0.617	0.33
59_N	223_S	0.617	0.33
196_L	290_V	0.616	0.33
325_S	474_W	0.616	0.33
356_P	451_W	0.615	0.32
377_S	397_L	0.615	0.32
327_E	488_K	0.615	0.32
56_T	106_V	0.615	0.32
189_P	503_L	0.614	0.32
363_L	457_I	0.613	0.32
66_R	280_A	0.612	0.32
180_A	186_A	0.612	0.32
157_E	160_P	0.611	0.32
223_S	478_R	0.611	0.32
505_N	508_P	0.611	0.32
293_A	422_V	0.610	0.32
64_I	112_P	0.609	0.32
335_E	387_G	0.609	0.32
31_L	35_T	0.609	0.32
430_P	447_L	0.608	0.32
178_G	186_A	0.604	0.32
103_A	106_V	0.604	0.32
76_E	87_A	0.604	0.32
239_A	243_Q	0.604	0.32
422_V	459_A	0.604	0.32
230_L	244_S	0.602	0.32
334_K	337_K	0.602	0.32
289_A	459_A	0.601	0.31
307_S	410_G	0.601	0.31
280_A	284_V	0.601	0.31
462_I	465_G	0.600	0.31
421_Q	436_A	0.600	0.31
432_G	498_H	0.599	0.31
270_V	392_A	0.599	0.31
233_Q	237_G	0.599	0.31
285_T	466_E	0.598	0.31
68_G	294_A	0.596	0.31
474_W	477_F	0.595	0.31
210_G	368_E	0.594	0.31
44_E	393_K	0.594	0.31
75_D	228_D	0.594	0.31
312_V	382_I	0.593	0.31
21_N	92_P	0.593	0.31
421_Q	497_L	0.592	0.31
389_G	412_L	0.592	0.31
25_I	53_V	0.591	0.31
271_I	297_L	0.590	0.31
348_A	366_V	0.590	0.31
167_D	490_T	0.590	0.31
130_T	442_S	0.590	0.31
77_T	80_R	0.589	0.31
180_A	430_P	0.589	0.31
390_E	393_K	0.587	0.30
137_T	199_H	0.587	0.30
316_I	404_A	0.587	0.30
33_K	44_E	0.587	0.30
100_L	329_G	0.586	0.30
202_F	206_V	0.586	0.30
394_Q	481_L	0.584	0.30
187_V	190_I	0.583	0.30
145_G	196_L	0.581	0.30
232_L	430_P	0.580	0.30
24_I	49_Q	0.580	0.30
354_P	359_K	0.580	0.30
94_P	350_R	0.579	0.30
471_D	475_E	0.577	0.30
289_A	296_L	0.577	0.30
44_E	57_D	0.576	0.30
173_H	409_C	0.575	0.30
70_V	92_P	0.575	0.30
464_T	470_E	0.575	0.30
112_P	115_G	0.574	0.29
14_I	47_V	0.574	0.29
340_D	350_R	0.572	0.29
35_T	46_D	0.572	0.29
171_L	202_F	0.571	0.29
314_D	404_A	0.570	0.29
210_G	434_A	0.570	0.29
27_N	60_Q	0.570	0.29
14_I	67_Y	0.570	0.29
266_V	297_L	0.569	0.29
137_T	193_I	0.569	0.29
41_L	53_V	0.569	0.29
421_Q	434_A	0.569	0.29
298_V	303_T	0.569	0.29
272_G	409_C	0.567	0.29
346_G	506_P	0.566	0.29
320_T	332_L	0.566	0.29
185_D	505_N	0.564	0.29
41_L	80_R	0.564	0.29
177_C	295_D	0.564	0.29
412_L	504_F	0.563	0.29
21_N	89_V	0.563	0.29
88_L	444_R	0.562	0.29
27_N	37_F	0.560	0.28
254_I	258_S	0.559	0.28
289_A	469_I	0.559	0.28
386_L	390_E	0.558	0.28
93_A	285_T	0.558	0.28
292_Y	297_L	0.557	0.28
145_G	203_G	0.556	0.28
44_E	55_L	0.556	0.28
278_S	358_N	0.556	0.28
271_I	304_V	0.554	0.28
329_G	333_I	0.553	0.28
353_N	359_K	0.553	0.28
274_Q	409_C	0.552	0.28
120_G	128_A	0.552	0.28
377_S	409_C	0.552	0.28
171_L	253_L	0.551	0.28
13_Y	268_D	0.551	0.28
128_A	419_N	0.550	0.28
430_P	451_W	0.550	0.28
280_A	507_A	0.550	0.28
204_G	226_D	0.549	0.28
15_K	21_N	0.549	0.28
384_G	392_A	0.549	0.28
183_A	348_A	0.548	0.28
135_G	169_V	0.547	0.28
222_A	232_L	0.547	0.28
86_E	445_H	0.547	0.28
43_L	48_P	0.547	0.28
310_T	343_L	0.547	0.28
158_L	250_E	0.546	0.28
84_I	273_L	0.544	0.27
142_C	295_D	0.544	0.27
37_F	43_L	0.544	0.27
271_I	274_Q	0.544	0.27
307_S	412_L	0.543	0.27
204_G	208_V	0.543	0.27
238_F	244_S	0.543	0.27
21_N	62_D	0.542	0.27
180_A	368_E	0.542	0.27
315_A	364_S	0.541	0.27
188_I	402_T	0.541	0.27
21_N	28_D	0.541	0.27
188_I	242_I	0.541	0.27
143_V	400_A	0.540	0.27
36_V	464_T	0.540	0.27
13_Y	65_V	0.540	0.27
140_V	365_N	0.539	0.27
252_R	255_R	0.539	0.27
252_R	335_E	0.539	0.27
41_L	55_L	0.538	0.27
365_N	373_S	0.538	0.27
37_F	127_S	0.538	0.27
340_D	508_P	0.538	0.27
293_A	457_I	0.537	0.27
401_A	504_F	0.537	0.27
128_A	297_L	0.537	0.27
128_A	262_V	0.537	0.27
368_E	371_L	0.536	0.27
208_V	221_I	0.536	0.27
360_K	416_A	0.536	0.27
89_V	368_E	0.536	0.27
140_V	177_C	0.536	0.27
139_S	329_G	0.535	0.27
180_A	343_L	0.535	0.27
83_W	87_A	0.535	0.27
215_K	508_P	0.534	0.27
163_P	253_L	0.534	0.27
140_V	213_C	0.534	0.27
130_T	373_S	0.533	0.27
475_E	491_W	0.532	0.27
134_L	170_P	0.532	0.27
275_C	308_E	0.530	0.26
457_I	472_V	0.530	0.26
110_R	115_G	0.529	0.26
213_C	295_D	0.529	0.26
129_G	190_I	0.528	0.26
293_A	296_L	0.528	0.26
340_D	343_L	0.528	0.26
175_Y	408_V	0.528	0.26
154_I	377_S	0.527	0.26
397_L	457_I	0.526	0.26
335_E	401_A	0.526	0.26
215_K	505_N	0.526	0.26
33_K	45_E	0.526	0.26
173_H	274_Q	0.525	0.26
119_E	485_S	0.525	0.26
222_A	249_A	0.525	0.26
198_K	480_I	0.524	0.26
155_K	158_L	0.524	0.26
343_L	397_L	0.523	0.26
223_S	393_K	0.523	0.26
31_L	59_N	0.522	0.26
103_A	110_R	0.522	0.26
364_S	374_V	0.522	0.26
350_R	402_T	0.521	0.26
33_K	62_D	0.521	0.26
469_I	472_V	0.521	0.26
100_L	333_I	0.521	0.26
292_Y	364_S	0.521	0.26
187_V	224_E	0.520	0.26
136_I	221_I	0.520	0.26
120_G	194_Q	0.520	0.26
48_P	191_R	0.519	0.26
56_T	84_I	0.519	0.26
280_A	410_G	0.518	0.26
354_P	375_A	0.518	0.26
414_L	431_Y	0.517	0.26
418_M	424_T	0.517	0.26
206_V	315_A	0.517	0.26
292_Y	474_W	0.517	0.26
76_E	488_K	0.517	0.26
112_P	116_Y	0.516	0.25
292_Y	473_G	0.516	0.25
269_L	274_Q	0.516	0.25
392_A	473_G	0.516	0.25
18_E	395_K	0.515	0.25
149_Y	242_I	0.515	0.25
281_F	460_G	0.515	0.25
210_G	318_L	0.515	0.25
292_Y	380_S	0.515	0.25
490_T	494_R	0.515	0.25
473_G	477_F	0.515	0.25
197_A	206_V	0.514	0.25
19_I	36_V	0.513	0.25
223_S	470_E	0.513	0.25
137_T	335_E	0.512	0.25
263_S	327_E	0.512	0.25
226_D	252_R	0.512	0.25
381_P	433_L	0.512	0.25
200_P	438_V	0.512	0.25
77_T	82_S	0.511	0.25
146_V	368_E	0.509	0.25
315_A	353_N	0.509	0.25
352_A	508_P	0.508	0.25
332_L	371_L	0.508	0.25
129_G	199_H	0.508	0.25
33_K	47_V	0.508	0.25
75_D	86_E	0.508	0.25
147_L	436_A	0.508	0.25
83_W	86_E	0.507	0.25
451_W	454_L	0.507	0.25
12_L	36_V	0.507	0.25
434_A	492_A	0.506	0.25
192_T	412_L	0.506	0.25
145_G	407_F	0.506	0.25
78_I	88_L	0.505	0.25
377_S	506_P	0.505	0.25
339_Y	454_L	0.504	0.25
233_Q	248_M	0.504	0.25
66_R	434_A	0.504	0.25
116_Y	474_W	0.503	0.25
91_M	351_S	0.503	0.25
93_A	340_D	0.502	0.25
13_Y	55_L	0.502	0.25
249_A	254_I	0.501	0.25
41_L	299_R	0.501	0.25
21_N	448_S	0.501	0.25
487_R	494_R	0.500	0.24
199_H	443_T	0.500	0.24

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3lazA	2	0.1784	100	0.863	Contact Map
3k3sA	2	0.1608	100	0.865	Contact Map
3teeA	1	0.2706	65.6	0.982	Contact Map
1vliA	2	0.1804	62.5	0.982	Contact Map
1msiA	1	0.1157	61.3	0.982	Contact Map
4ur6A	2	0.1216	54.3	0.983	Contact Map
3uplA	2	0.1922	51.2	0.983	Contact Map
1ucsA	1	0.1216	50	0.983	Contact Map
1wiwA	2	0.3176	46	0.984	Contact Map
2wqpA	2	0.1627	39.1	0.984	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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