GREMLIN Database
NARJ - Probable nitrate reductase molybdenum cofactor assembly chaperone NarJ
UniProt: P42178 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 184 (167)
Sequences: 989 (739)
Seq/√Len: 57.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
32_K55_A3.9551.00
50_F161_L3.7551.00
32_K52_E3.2431.00
59_P63_I2.9421.00
117_Y120_L2.8831.00
100_N104_Q2.7721.00
152_E163_H2.7381.00
53_T65_H2.7161.00
49_H160_E2.6161.00
69_T156_S2.6071.00
29_P55_A2.4841.00
50_F160_E2.3451.00
53_T157_I2.3441.00
103_E108_L2.3301.00
100_N103_E2.3101.00
22_E26_A2.2631.00
50_F54_S2.2291.00
12_A31_W2.2191.00
13_L165_L1.9781.00
148_A166_L1.9161.00
54_S62_L1.9061.00
145_R148_A1.8881.00
85_S94_E1.8651.00
58_S61_A1.8070.99
22_E63_I1.7580.99
72_F82_Y1.7390.99
27_E30_D1.7360.99
78_M119_P1.7280.99
24_W54_S1.6420.99
109_P120_L1.5890.98
147_L162_L1.5740.98
35_I38_I1.5620.98
36_Q48_L1.5570.98
67_V71_D1.5270.98
11_S127_A1.4850.98
76_T150_R1.4530.97
125_A133_A1.4390.97
12_A164_V1.4380.97
10_F128_A1.4230.97
148_A162_L1.4220.97
13_L161_L1.4170.97
47_L161_L1.3940.96
10_F168_A1.3790.96
28_L51_F1.3660.96
81_T98_L1.3640.96
118_L144_V1.3640.96
121_M136_V1.3560.96
89_R92_G1.3330.95
87_E150_R1.3300.95
60_E64_E1.3060.95
99_K103_E1.3030.95
109_P124_F1.2970.95
74_K82_Y1.2830.94
29_P33_A1.2490.94
101_T136_V1.2350.93
171_N174_V1.2280.93
28_L55_A1.2150.93
65_H158_Y1.2140.93
81_T94_E1.1920.92
40_N45_E1.1880.92
98_L129_E1.1520.90
102_Y124_F1.1400.90
8_I34_L1.1350.90
57_Y65_H1.1340.90
98_L101_T1.1320.90
128_A132_A1.1280.89
99_K109_P1.1270.89
35_I44_R1.1230.89
57_Y61_A1.1080.89
10_F134_R1.1020.88
132_A135_S1.0920.88
85_S90_E1.0790.87
73_G76_T1.0640.87
135_S139_K1.0580.86
152_E159_A1.0410.85
46_K49_H1.0400.85
34_L37_E1.0350.85
23_E26_A1.0320.85
18_S117_Y1.0230.84
11_S15_C1.0210.84
61_A64_E1.0170.84
46_K160_E1.0120.84
148_A163_H1.0110.84
105_S124_F1.0040.83
151_L156_S0.9950.83
64_E68_Y0.9930.82
93_I97_H0.9870.82
149_S153_K0.9870.82
11_S14_S0.9810.82
74_K94_E0.9680.81
103_E109_P0.9580.80
45_E49_H0.9550.80
86_G94_E0.9470.79
15_C27_E0.9360.79
33_A36_Q0.9240.78
90_E95_L0.9150.77
134_R138_E0.9040.76
76_T154_N0.9000.76
32_K48_L0.8920.75
23_E27_E0.8920.75
142_S146_E0.8860.75
13_L164_V0.8830.74
95_L142_S0.8770.74
80_V87_E0.8760.74
10_F125_A0.8730.74
88_Q146_E0.8640.73
93_I121_M0.8620.73
83_F143_N0.8600.72
107_F128_A0.8590.72
61_A65_H0.8590.72
82_Y121_M0.8570.72
118_L141_L0.8560.72
83_F95_L0.8540.72
45_E175_R0.8420.71
67_V117_Y0.8340.70
33_A37_E0.8330.70
83_F87_E0.8290.70
93_I96_L0.8260.69
26_A29_P0.8250.69
16_L83_F0.8220.69
9_T38_I0.8220.69
93_I140_Y0.8180.69
43_I167_A0.8140.68
73_G154_N0.8040.67
82_Y169_L0.8020.67
101_T104_Q0.7980.67
60_E76_T0.7980.67
81_T95_L0.7900.66
85_S98_L0.7900.66
68_Y171_N0.7880.66
45_E52_E0.7870.66
78_M147_L0.7850.65
21_D25_R0.7780.65
107_F127_A0.7690.64
31_W34_L0.7670.64
105_S127_A0.7560.62
57_Y62_L0.7470.62
63_I120_L0.7400.61
69_T157_I0.7390.61
23_E29_P0.7330.60
85_S89_R0.7300.60
44_R48_L0.7300.60
145_R166_L0.7270.59
50_F107_F0.7180.59
53_T57_Y0.7150.58
84_N98_L0.7110.58
141_L169_L0.7090.58
10_F107_F0.7060.57
72_F142_S0.7030.57
40_N147_L0.7030.57
72_F85_S0.7010.57
28_L110_T0.6770.54
77_N150_R0.6740.54
82_Y156_S0.6740.54
95_L114_L0.6740.54
77_N94_E0.6720.54
147_L156_S0.6710.53
82_Y85_S0.6700.53
83_F88_Q0.6690.53
82_Y88_Q0.6650.53
17_L71_D0.6650.53
93_I107_F0.6630.53
47_L51_F0.6630.53
95_L143_N0.6610.52
96_L101_T0.6560.52
42_Q131_E0.6530.51
113_E147_L0.6510.51
36_Q46_K0.6510.51
80_V121_M0.6490.51
12_A64_E0.6440.50
38_I126_A0.6300.49
22_E59_P0.6260.49
141_L166_L0.6250.48
95_L168_A0.6250.48
148_A171_N0.6240.48
92_G156_S0.6210.48
73_G143_N0.6130.47
60_E95_L0.6120.47
86_G91_R0.6120.47
24_W31_W0.6080.47
88_Q140_Y0.6050.46
18_S112_K0.6040.46
25_R59_P0.6010.46
15_C140_Y0.5980.45
21_D127_A0.5970.45
30_D33_A0.5950.45
74_K89_R0.5940.45
16_L74_K0.5940.45
147_L168_A0.5920.45
26_A131_E0.5910.45
27_E31_W0.5860.44
86_G89_R0.5860.44
166_L169_L0.5850.44
97_H139_K0.5840.44
14_S27_E0.5840.44
11_S126_A0.5830.44
117_Y129_E0.5830.44
172_I175_R0.5780.43
10_F81_T0.5780.43
94_E123_E0.5730.43
75_K79_Y0.5710.43
43_I168_A0.5690.42
80_V143_N0.5690.42
24_W72_F0.5680.42
84_N140_Y0.5670.42
82_Y143_N0.5660.42
82_Y91_R0.5660.42
100_N135_S0.5660.42
36_Q56_S0.5640.42
45_E131_E0.5640.42
43_I131_E0.5640.42
75_K88_Q0.5600.41
71_D111_E0.5530.41
31_W51_F0.5510.40
95_L102_Y0.5500.40
130_I163_H0.5490.40
118_L122_L0.5480.40
81_T85_S0.5420.39
48_L52_E0.5390.39
25_R29_P0.5380.39
87_E162_L0.5370.39
91_R98_L0.5340.39
142_S149_S0.5330.39
120_L152_E0.5320.38
78_M123_E0.5310.38
8_I13_L0.5310.38
84_N143_N0.5300.38
32_K39_G0.5300.38
59_P138_E0.5290.38
81_T121_M0.5250.38
14_S66_Y0.5240.38
37_E131_E0.5240.38
101_T112_K0.5210.37
78_M81_T0.5210.37
89_R123_E0.5190.37
10_F105_S0.5180.37
64_E165_L0.5150.37
49_H129_E0.5150.37
42_Q48_L0.5140.37
23_E33_A0.5130.36
11_S167_A0.5100.36
14_S133_A0.5090.36
18_S147_L0.5090.36
123_E159_A0.5090.36
72_F81_T0.5080.36
77_N103_E0.5060.36
119_P123_E0.5030.35
120_L162_L0.5030.35
79_Y117_Y0.5000.35
24_W63_I0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2o9xA 2 0.837 99.9 0.564 Contact Map
1n1cA 2 0.9402 99.9 0.577 Contact Map
1s9uA 1 0.9674 99.9 0.603 Contact Map
2xolA 2 0.788 98.3 0.826 Contact Map
3htkC 1 0.4022 39.4 0.938 Contact Map
4fddA 1 0.8913 25.4 0.943 Contact Map
3w3wA 1 0.9185 18.5 0.947 Contact Map
1u6gC 1 0.5761 15.3 0.949 Contact Map
1vsy5 1 0.7337 14.8 0.949 Contact Map
4g3aA 1 0.587 13.9 0.95 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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