ASNH - BACSU - GREMLIN Contacts

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ASNH - Asparagine synthetase [glutamine-hydrolyzing] 2

UniProt:	P42113	Sequences: MCGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDSKVGFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCEVIVHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFASEIKSLFSHPHCPRQFNWKEALSDIWLSGEAASNHKETTSFFVNIQNLDAGHYLEINLTTNERKTASYWSLQDILLRQGYRENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSGGIDSAAVAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPESYKHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAENPSWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQADPWQSYVLTKYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSVLRKSLTNELHTSYTHRPKVPFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHSDASSIIQVEHIHAIMTYLEDDPEFTNFEFLLRLVNMGLLSKMTKETPSVQLDITSHLESITIKDWHSQEGDIASRLNISANKCEGQDILALNPGVTLLRPESDSEHCIYIAEEGFIQFIVSEEDVGAWLHILCDINGKDTLHTILDRHGVSLEEVAKYIQEAIEHNIILIKQKNLPEGAYR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	747 (578)
Sequences:	3298 (2620)
Seq/√Len:	109.0

ECOLI - ASNB
BACSU - ASNH ASNB ASNO

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
37_D	62_Q	4.356	1.00
27_A	49_A	3.978	1.00
174_Q	202_V	3.927	1.00
114_G	117_D	3.906	1.00
93_H	110_E	3.814	1.00
294_H	322_P	3.613	1.00
23_L	47_G	3.613	1.00
282_A	518_L	3.538	1.00
66_L	73_V	3.445	1.00
134_K	216_N	3.366	1.00
137_L	147_L	3.103	1.00
89_S	118_D	3.062	1.00
107_L	111_K	3.053	1.00
134_K	214_E	3.020	1.00
272_L	284_A	2.891	1.00
255_L	495_W	2.891	1.00
244_H	247_D	2.864	1.00
144_I	485_V	2.838	1.00
107_L	115_F	2.826	1.00
61_G	99_S	2.818	1.00
142_F	493_V	2.809	1.00
366_Y	372_P	2.754	1.00
257_A	289_E	2.743	1.00
346_W	608_M	2.711	1.00
516_K	519_T	2.615	1.00
313_H	325_Q	2.570	1.00
258_D	491_R	2.566	1.00
207_L	213_L	2.559	1.00
74_V	101_C	2.552	1.00
271_G	374_L	2.543	1.00
38_E	51_R	2.534	1.00
253_R	520_N	2.476	1.00
314_W	525_S	2.472	1.00
256_L	286_F	2.458	1.00
245_P	516_K	2.397	1.00
115_F	119_I	2.375	1.00
126_A	137_L	2.341	1.00
212_Y	225_A	2.314	1.00
476_A	483_N	2.309	1.00
113_I	225_A	2.296	1.00
163_K	349_E	2.276	1.00
141_R	490_H	2.247	1.00
603_G	607_K	2.246	1.00
116_V	212_Y	2.228	1.00
176_N	202_V	2.195	1.00
176_N	198_T	2.186	1.00
157_I	168_H	2.163	1.00
111_K	118_D	2.151	1.00
406_I	410_N	2.130	1.00
67_N	71_S	2.082	1.00
313_H	317_K	2.080	1.00
524_T	528_H	2.063	1.00
67_N	109_E	2.059	1.00
93_H	106_H	2.057	1.00
6_G	158_F	2.044	1.00
208_D	224_T	2.027	1.00
245_P	503_L	2.003	1.00
56_L	83_Y	2.002	1.00
76_V	80_I	1.953	1.00
156_L	215_I	1.951	1.00
211_H	226_S	1.927	1.00
104_I	119_I	1.911	1.00
245_P	512_S	1.903	1.00
294_H	324_H	1.875	1.00
116_V	138_V	1.871	1.00
123_F	138_V	1.830	1.00
120_I	490_H	1.828	1.00
113_I	214_E	1.810	1.00
137_L	213_L	1.797	1.00
258_D	262_R	1.765	1.00
364_H	476_A	1.764	1.00
519_T	528_H	1.760	1.00
72_I	105_V	1.754	1.00
296_F	373_N	1.753	1.00
72_I	109_E	1.747	1.00
491_R	494_E	1.747	1.00
248_L	499_I	1.739	1.00
84_K	265_Q	1.737	1.00
343_H	365_K	1.733	1.00
251_G	254_E	1.690	1.00
450_A	453_W	1.690	1.00
295_T	321_L	1.673	1.00
108_Y	136_F	1.669	1.00
24_K	38_E	1.668	1.00
251_G	255_L	1.657	1.00
312_A	316_A	1.645	1.00
208_D	211_H	1.643	1.00
520_N	524_T	1.643	1.00
159_A	164_S	1.634	1.00
73_V	130_K	1.633	1.00
253_R	517_S	1.631	1.00
120_I	491_R	1.631	1.00
128_W	135_V	1.630	1.00
253_R	521_E	1.622	1.00
347_I	478_A	1.621	1.00
490_H	494_E	1.619	1.00
120_I	258_D	1.617	1.00
120_I	262_R	1.612	1.00
583_Y	592_N	1.610	1.00
245_P	506_D	1.596	1.00
506_D	512_S	1.595	1.00
115_F	136_F	1.593	1.00
43_D	130_K	1.588	1.00
331_G	334_E	1.587	1.00
71_S	131_N	1.577	1.00
144_I	263_C	1.573	1.00
252_Y	387_N	1.569	1.00
115_F	125_I	1.568	1.00
30_I	164_S	1.566	1.00
211_H	224_T	1.565	1.00
243_L	251_G	1.559	1.00
108_Y	127_I	1.549	1.00
383_S	487_F	1.549	1.00
116_V	136_F	1.546	1.00
245_P	249_I	1.545	1.00
512_S	516_K	1.539	1.00
74_V	127_I	1.539	1.00
23_L	49_A	1.523	1.00
371_R	375_K	1.518	1.00
284_A	321_L	1.513	1.00
423_N	426_R	1.511	1.00
67_N	106_H	1.509	1.00
74_V	105_V	1.507	1.00
252_Y	495_W	1.507	1.00
206_N	350_T	1.503	1.00
243_L	248_L	1.501	1.00
69_D	109_E	1.499	1.00
22_I	169_P	1.496	1.00
5_A	49_A	1.496	1.00
281_A	315_L	1.495	1.00
333_D	339_E	1.493	1.00
128_W	133_N	1.492	1.00
216_N	219_T	1.492	1.00
282_A	517_S	1.491	1.00
387_N	496_V	1.487	1.00
262_R	491_R	1.486	1.00
264_L	287_A	1.485	1.00
107_L	119_I	1.482	1.00
297_T	312_A	1.478	1.00
88_A	91_H	1.472	1.00
125_I	138_V	1.466	1.00
136_F	214_E	1.464	1.00
151_E	205_Q	1.459	1.00
80_I	104_I	1.459	1.00
133_N	217_L	1.456	1.00
42_I	47_G	1.455	1.00
5_A	27_A	1.448	1.00
149_Y	205_Q	1.446	1.00
176_N	205_Q	1.443	1.00
266_S	270_V	1.426	1.00
8_I	46_V	1.426	1.00
24_K	28_D	1.422	1.00
457_V	460_K	1.398	1.00
37_D	50_F	1.395	1.00
32_Y	161_E	1.392	1.00
569_S	603_G	1.390	1.00
89_S	111_K	1.385	1.00
311_Y	529_R	1.375	1.00
255_L	491_R	1.372	1.00
56_L	266_S	1.369	1.00
152_L	155_E	1.367	1.00
348_C	475_I	1.365	1.00
165_L	171_C	1.355	1.00
59_V	97_T	1.344	1.00
6_G	126_A	1.339	1.00
519_T	524_T	1.338	1.00
578_H	582_T	1.331	1.00
27_A	51_R	1.324	0.99
295_T	323_N	1.321	0.99
263_C	485_V	1.318	0.99
216_N	220_N	1.316	0.99
213_L	222_R	1.309	0.99
27_A	40_Y	1.309	0.99
423_N	427_V	1.307	0.99
108_Y	115_F	1.306	0.99
451_D	454_Q	1.305	0.99
5_A	26_M	1.298	0.99
456_Y	460_K	1.294	0.99
106_H	109_E	1.282	0.99
76_V	101_C	1.281	0.99
129_D	132_K	1.280	0.99
379_T	483_N	1.276	0.99
8_I	135_V	1.270	0.99
104_I	115_F	1.266	0.99
547_M	551_L	1.265	0.99
68_E	109_E	1.264	0.99
24_K	40_Y	1.261	0.99
457_V	461_Y	1.261	0.99
92_N	95_F	1.259	0.99
284_A	295_T	1.256	0.99
499_I	513_V	1.254	0.99
136_F	212_Y	1.252	0.99
48_F	158_F	1.250	0.99
255_L	492_L	1.250	0.99
381_Q	471_H	1.248	0.99
402_W	405_F	1.247	0.99
185_W	602_M	1.247	0.99
456_Y	459_T	1.246	0.99
249_I	516_K	1.242	0.99
83_Y	98_T	1.242	0.99
116_V	125_I	1.240	0.99
257_A	286_F	1.239	0.99
284_A	319_L	1.236	0.99
55_I	376_V	1.230	0.99
31_S	38_E	1.229	0.99
301_Q	331_G	1.228	0.99
65_F	105_V	1.218	0.99
367_A	377_M	1.217	0.99
165_L	204_I	1.215	0.99
216_N	221_E	1.215	0.99
388_G	505_K	1.214	0.99
31_S	51_R	1.212	0.99
68_E	106_H	1.208	0.99
584_L	591_T	1.207	0.99
83_Y	265_Q	1.199	0.99
454_Q	458_L	1.194	0.99
262_R	265_Q	1.190	0.99
127_I	136_F	1.189	0.99
71_S	109_E	1.182	0.99
83_Y	103_V	1.181	0.99
120_I	489_D	1.176	0.99
138_V	212_Y	1.167	0.99
314_W	317_K	1.166	0.99
450_A	501_D	1.162	0.99
552_K	555_N	1.160	0.99
120_I	263_C	1.160	0.99
56_L	265_Q	1.159	0.99
28_D	51_R	1.156	0.99
71_S	132_K	1.146	0.99
243_L	247_D	1.146	0.99
6_G	137_L	1.128	0.98
95_F	103_V	1.126	0.98
74_V	125_I	1.125	0.98
4_L	75_M	1.121	0.98
410_N	414_M	1.121	0.98
250_E	520_N	1.119	0.98
207_L	224_T	1.118	0.98
288_A	319_L	1.117	0.98
162_I	204_I	1.114	0.98
249_I	517_S	1.109	0.98
65_F	101_C	1.107	0.98
352_F	356_E	1.101	0.98
93_H	109_E	1.097	0.98
251_G	495_W	1.096	0.98
226_S	229_S	1.094	0.98
272_L	295_T	1.093	0.98
453_W	456_Y	1.091	0.98
340_S	365_K	1.087	0.98
113_I	136_F	1.085	0.98
334_E	365_K	1.082	0.98
20_F	24_K	1.079	0.98
301_Q	327_L	1.079	0.98
196_E	466_M	1.076	0.98
259_S	263_C	1.076	0.98
166_F	173_R	1.075	0.98
250_E	254_E	1.069	0.98
453_W	460_K	1.068	0.98
67_N	70_G	1.066	0.98
104_I	125_I	1.062	0.98
122_M	144_I	1.061	0.98
455_S	458_L	1.059	0.97
253_R	257_A	1.059	0.97
30_I	51_R	1.058	0.97
551_L	582_T	1.058	0.97
459_T	462_R	1.057	0.97
406_I	417_L	1.053	0.97
283_V	378_L	1.052	0.97
408_S	412_M	1.049	0.97
472_E	483_N	1.048	0.97
574_V	578_H	1.045	0.97
232_D	497_C	1.044	0.97
365_K	372_P	1.042	0.97
45_K	133_N	1.039	0.97
287_A	293_L	1.037	0.97
248_L	503_L	1.031	0.97
48_F	75_M	1.029	0.97
157_I	165_L	1.029	0.97
286_F	521_E	1.028	0.97
455_S	459_T	1.026	0.97
5_A	159_A	1.022	0.97
150_T	165_L	1.015	0.97
61_G	97_T	1.011	0.97
453_W	459_T	1.010	0.97
56_L	97_T	1.009	0.97
41_H	73_V	1.006	0.97
74_V	104_I	1.004	0.97
252_Y	492_L	0.997	0.96
125_I	136_F	0.996	0.96
29_A	167_S	0.995	0.96
126_A	158_F	0.993	0.96
509_W	515_R	0.992	0.96
334_E	339_E	0.987	0.96
377_M	483_N	0.982	0.96
577_I	599_L	0.980	0.96
4_L	50_F	0.980	0.96
37_D	54_S	0.979	0.96
201_F	609_T	0.979	0.96
453_W	457_V	0.977	0.96
126_A	135_V	0.976	0.96
342_K	549_H	0.973	0.96
553_K	600_V	0.968	0.96
450_A	454_Q	0.966	0.96
228_W	494_E	0.966	0.96
169_P	173_R	0.965	0.96
2_C	77_N	0.964	0.96
72_I	131_N	0.964	0.96
393_T	459_T	0.962	0.96
84_K	98_T	0.956	0.95
270_V	375_K	0.954	0.95
256_L	282_A	0.953	0.95
210_G	227_Y	0.950	0.95
229_S	461_Y	0.947	0.95
210_G	228_W	0.940	0.95
579_A	583_Y	0.940	0.95
549_H	552_K	0.937	0.95
174_Q	203_N	0.937	0.95
551_L	578_H	0.937	0.95
71_S	130_K	0.937	0.95
185_W	572_I	0.934	0.95
104_I	127_I	0.934	0.95
255_L	258_D	0.933	0.95
54_S	58_L	0.931	0.95
252_Y	496_V	0.928	0.95
245_P	513_V	0.926	0.95
551_L	581_M	0.926	0.95
30_I	159_A	0.926	0.95
68_E	93_H	0.925	0.95
495_W	499_I	0.924	0.94
147_L	207_L	0.922	0.94
299_L	309_A	0.922	0.94
517_S	520_N	0.921	0.94
452_P	456_Y	0.921	0.94
249_I	520_N	0.916	0.94
442_L	445_N	0.916	0.94
148_F	474_R	0.914	0.94
87_K	95_F	0.914	0.94
360_K	381_Q	0.913	0.94
21_H	24_K	0.913	0.94
363_L	367_A	0.908	0.94
452_P	459_T	0.906	0.94
309_A	327_L	0.906	0.94
543_T	584_L	0.905	0.94
246_D	249_I	0.903	0.94
191_A	196_E	0.901	0.94
552_K	556_Y	0.898	0.94
576_H	579_A	0.897	0.94
449_Q	453_W	0.897	0.94
399_N	402_W	0.897	0.94
23_L	40_Y	0.896	0.94
309_A	325_Q	0.896	0.94
348_C	357_Q	0.896	0.94
381_Q	472_E	0.894	0.93
273_F	364_H	0.890	0.93
256_L	487_F	0.887	0.93
183_D	198_T	0.887	0.93
150_T	204_I	0.886	0.93
106_H	110_E	0.885	0.93
407_E	410_N	0.885	0.93
241_E	248_L	0.885	0.93
39_Q	62_Q	0.884	0.93
356_E	471_H	0.881	0.93
26_M	168_H	0.881	0.93
558_L	607_K	0.878	0.93
496_V	499_I	0.878	0.93
281_A	311_Y	0.877	0.93
281_A	522_L	0.873	0.93
122_M	145_K	0.872	0.93
150_T	171_C	0.871	0.93
283_V	487_F	0.870	0.93
28_D	38_E	0.868	0.92
439_L	443_K	0.866	0.92
72_I	108_Y	0.865	0.92
354_G	357_Q	0.864	0.92
292_D	322_P	0.863	0.92
31_S	480_H	0.861	0.92
272_L	287_A	0.861	0.92
116_V	227_Y	0.859	0.92
83_Y	87_K	0.859	0.92
215_I	222_R	0.859	0.92
181_L	602_M	0.857	0.92
348_C	352_F	0.854	0.92
258_D	261_H	0.853	0.92
248_L	495_W	0.851	0.92
360_K	475_I	0.851	0.92
470_W	474_R	0.851	0.92
68_E	71_S	0.849	0.92
122_M	263_C	0.849	0.92
603_G	606_S	0.848	0.92
549_H	553_K	0.846	0.91
377_M	476_A	0.842	0.91
8_I	215_I	0.842	0.91
70_G	96_K	0.841	0.91
353_C	357_Q	0.839	0.91
81_Y	145_K	0.837	0.91
354_G	471_H	0.837	0.91
311_Y	315_L	0.837	0.91
27_A	38_E	0.835	0.91
324_H	373_N	0.835	0.91
455_S	460_K	0.834	0.91
356_E	359_Y	0.834	0.91
72_I	106_H	0.832	0.91
125_I	137_L	0.831	0.91
572_I	577_I	0.830	0.91
108_Y	129_D	0.829	0.91
7_I	157_I	0.828	0.91
547_M	585_E	0.827	0.91
81_Y	122_M	0.826	0.90
111_K	115_F	0.826	0.90
114_G	118_D	0.824	0.90
487_F	514_L	0.824	0.90
113_I	134_K	0.823	0.90
104_I	116_V	0.823	0.90
27_A	30_I	0.822	0.90
60_N	99_S	0.822	0.90
392_T	395_S	0.820	0.90
43_D	46_V	0.820	0.90
41_H	128_W	0.817	0.90
22_I	168_H	0.816	0.90
297_T	363_L	0.814	0.90
132_K	216_N	0.814	0.90
58_L	267_D	0.813	0.90
452_P	455_S	0.813	0.90
71_S	106_H	0.812	0.90
149_Y	156_L	0.812	0.90
469_C	485_V	0.812	0.90
454_Q	457_V	0.807	0.89
126_A	213_L	0.805	0.89
188_G	598_R	0.805	0.89
207_L	211_H	0.803	0.89
400_P	403_E	0.802	0.89
3_G	33_R	0.802	0.89
156_L	207_L	0.800	0.89
85_E	265_Q	0.796	0.89
299_L	327_L	0.796	0.89
141_R	228_W	0.796	0.89
410_N	417_L	0.794	0.89
25_G	167_S	0.794	0.89
273_F	367_A	0.793	0.89
270_V	376_V	0.789	0.88
55_I	375_K	0.786	0.88
340_S	362_H	0.785	0.88
29_A	164_S	0.785	0.88
256_L	518_L	0.780	0.88
75_M	126_A	0.779	0.88
388_G	456_Y	0.779	0.88
539_D	593_F	0.778	0.88
56_L	99_S	0.778	0.88
289_E	521_E	0.777	0.88
18_C	47_G	0.777	0.88
213_L	224_T	0.776	0.88
425_F	429_E	0.774	0.87
176_N	179_E	0.774	0.87
252_Y	256_L	0.774	0.87
44_S	133_N	0.773	0.87
151_E	222_R	0.772	0.87
342_K	608_M	0.771	0.87
244_H	248_L	0.771	0.87
354_G	359_Y	0.769	0.87
67_N	72_I	0.768	0.87
21_H	25_G	0.768	0.87
343_H	346_W	0.768	0.87
428_W	432_F	0.765	0.87
162_I	201_F	0.764	0.87
361_F	365_K	0.762	0.87
386_F	493_V	0.762	0.87
166_F	204_I	0.761	0.86
349_E	474_R	0.760	0.86
58_L	268_V	0.759	0.86
402_W	406_I	0.755	0.86
285_H	319_L	0.755	0.86
571_I	606_S	0.755	0.86
549_H	600_V	0.753	0.86
249_I	253_R	0.752	0.86
133_N	219_T	0.752	0.86
431_H	434_L	0.749	0.86
518_L	521_E	0.749	0.86
85_E	262_R	0.749	0.86
437_I	442_L	0.747	0.85
492_L	496_V	0.747	0.85
200_F	350_T	0.747	0.85
23_L	42_I	0.746	0.85
576_H	580_I	0.746	0.85
311_Y	314_W	0.746	0.85
454_Q	459_T	0.745	0.85
436_P	439_L	0.744	0.85
117_D	225_A	0.741	0.85
401_S	404_G	0.740	0.85
2_C	79_E	0.740	0.85
515_R	528_H	0.739	0.85
361_F	479_N	0.739	0.85
137_L	158_F	0.729	0.84
556_Y	560_E	0.729	0.84
414_M	417_L	0.728	0.84
317_K	320_H	0.727	0.84
37_D	61_G	0.724	0.84
342_K	604_L	0.723	0.84
360_K	472_E	0.723	0.84
86_L	119_I	0.723	0.84
400_P	404_G	0.722	0.83
77_N	390_Y	0.721	0.83
359_Y	471_H	0.720	0.83
586_D	589_E	0.720	0.83
260_V	286_F	0.719	0.83
82_N	85_E	0.718	0.83
437_I	441_Y	0.717	0.83
403_E	406_I	0.715	0.83
424_I	432_F	0.715	0.83
157_I	171_C	0.713	0.83
345_L	601_N	0.712	0.83
124_S	147_L	0.711	0.83
569_S	574_V	0.711	0.83
37_D	75_M	0.711	0.83
410_N	413_E	0.710	0.82
273_F	354_G	0.710	0.82
517_S	521_E	0.707	0.82
326_V	366_Y	0.706	0.82
147_L	156_L	0.706	0.82
381_Q	468_N	0.706	0.82
532_V	535_F	0.706	0.82
22_I	25_G	0.705	0.82
12_A	19_T	0.705	0.82
360_K	471_H	0.705	0.82
606_S	610_K	0.704	0.82
39_Q	51_R	0.704	0.82
107_L	118_D	0.703	0.82
36_D	375_K	0.703	0.82
385_E	390_Y	0.702	0.82
583_Y	590_F	0.701	0.82
5_A	30_I	0.701	0.82
382_G	488_L	0.700	0.82
352_F	357_Q	0.699	0.81
141_R	263_C	0.699	0.81
66_L	70_G	0.698	0.81
175_F	200_F	0.698	0.81
179_E	198_T	0.698	0.81
367_A	374_L	0.697	0.81
2_C	390_Y	0.697	0.81
312_A	325_Q	0.697	0.81
197_T	208_D	0.696	0.81
492_L	495_W	0.696	0.81
520_N	527_T	0.696	0.81
405_F	408_S	0.694	0.81
315_L	526_Y	0.694	0.81
256_L	492_L	0.693	0.81
23_L	27_A	0.692	0.81
348_C	470_W	0.690	0.81
461_Y	464_L	0.690	0.81
355_P	359_Y	0.687	0.80
584_L	592_N	0.686	0.80
458_L	462_R	0.686	0.80
142_F	460_K	0.686	0.80
426_R	430_E	0.685	0.80
356_E	381_Q	0.685	0.80
271_G	367_A	0.683	0.80
409_V	412_M	0.682	0.80
340_S	358_L	0.682	0.80
253_R	286_F	0.681	0.80
268_V	376_V	0.681	0.80
410_N	415_N	0.680	0.80
559_I	603_G	0.680	0.80
80_I	119_I	0.680	0.80
29_A	346_W	0.679	0.80
260_V	283_V	0.679	0.80
352_F	355_P	0.679	0.80
257_A	521_E	0.678	0.79
269_E	375_K	0.678	0.79
176_N	180_A	0.677	0.79
67_N	73_V	0.675	0.79
151_E	156_L	0.675	0.79
454_Q	460_K	0.674	0.79
555_N	559_I	0.673	0.79
296_F	374_L	0.671	0.79
149_Y	213_L	0.671	0.79
151_E	154_H	0.670	0.79
205_Q	224_T	0.670	0.79
543_T	591_T	0.667	0.78
251_G	498_G	0.667	0.78
360_K	535_F	0.667	0.78
459_T	464_L	0.666	0.78
9_N	12_A	0.666	0.78
556_Y	559_I	0.666	0.78
171_C	204_I	0.665	0.78
407_E	411_T	0.664	0.78
214_E	223_K	0.664	0.78
74_V	119_I	0.663	0.78
361_F	478_A	0.663	0.78
307_E	327_L	0.662	0.78
427_V	431_H	0.662	0.78
156_L	213_L	0.660	0.78
307_E	310_K	0.660	0.78
142_F	487_F	0.660	0.78
371_R	377_M	0.659	0.78
115_F	138_V	0.659	0.78
216_N	223_K	0.658	0.77
553_K	604_L	0.658	0.77
556_Y	607_K	0.658	0.77
354_G	363_L	0.656	0.77
550_L	581_M	0.656	0.77
65_F	97_T	0.655	0.77
509_W	528_H	0.653	0.77
249_I	252_Y	0.652	0.77
252_Y	513_V	0.652	0.77
282_A	520_N	0.651	0.77
144_I	490_H	0.651	0.77
55_I	58_L	0.650	0.77
570_S	603_G	0.649	0.76
353_C	356_E	0.649	0.76
72_I	132_K	0.649	0.76
377_M	481_I	0.648	0.76
188_G	191_A	0.647	0.76
398_E	401_S	0.647	0.76
449_Q	452_P	0.646	0.76
423_N	430_E	0.645	0.76
423_N	428_W	0.644	0.76
294_H	374_L	0.643	0.76
273_F	472_E	0.642	0.76
397_A	401_S	0.642	0.76
104_I	138_V	0.641	0.76
459_T	463_D	0.641	0.76
424_I	428_W	0.641	0.76
20_F	42_I	0.640	0.75
423_N	432_F	0.638	0.75
426_R	429_E	0.638	0.75
2_C	385_E	0.638	0.75
550_L	553_K	0.637	0.75
453_W	504_R	0.637	0.75
352_F	381_Q	0.635	0.75
252_Y	255_L	0.635	0.75
113_I	212_Y	0.633	0.75
9_N	155_E	0.633	0.75
435_S	438_N	0.632	0.75
7_I	168_H	0.632	0.75
420_L	423_N	0.632	0.75
52_R	77_N	0.632	0.75
550_L	600_V	0.631	0.74
141_R	494_E	0.631	0.74
56_L	84_K	0.631	0.74
22_I	167_S	0.630	0.74
152_L	157_I	0.630	0.74
405_F	410_N	0.629	0.74
344_L	475_I	0.628	0.74
463_D	468_N	0.627	0.74
273_F	471_H	0.626	0.74
438_N	442_L	0.625	0.74
285_H	521_E	0.624	0.74
199_S	204_I	0.624	0.74
67_N	93_H	0.623	0.74
130_K	133_N	0.623	0.74
201_F	204_I	0.622	0.73
163_K	346_W	0.620	0.73
592_N	595_F	0.620	0.73
245_P	248_L	0.619	0.73
166_F	609_T	0.619	0.73
48_F	135_V	0.617	0.73
27_A	47_G	0.617	0.73
456_Y	461_Y	0.616	0.73
83_Y	95_F	0.615	0.73
459_T	465_Q	0.613	0.72
155_E	168_H	0.613	0.72
271_G	377_M	0.613	0.72
354_G	360_K	0.612	0.72
362_H	365_K	0.610	0.72
151_E	155_E	0.610	0.72
2_C	52_R	0.610	0.72
423_N	429_E	0.609	0.72
217_L	221_E	0.608	0.72
397_A	402_W	0.608	0.72
412_M	415_N	0.607	0.72
460_K	465_Q	0.607	0.72
67_N	105_V	0.606	0.71
2_C	101_C	0.604	0.71
573_Q	576_H	0.603	0.71
353_C	598_R	0.603	0.71
582_T	586_D	0.603	0.71
83_Y	97_T	0.603	0.71
343_H	347_I	0.602	0.71
87_K	103_V	0.602	0.71
371_R	481_I	0.602	0.71
427_V	430_E	0.601	0.71
116_V	119_I	0.600	0.71
23_L	26_M	0.600	0.71
2_C	55_I	0.599	0.71
381_Q	485_V	0.598	0.70
97_T	102_E	0.597	0.70
252_Y	517_S	0.597	0.70
584_L	596_L	0.597	0.70
442_L	448_S	0.597	0.70
348_C	381_Q	0.597	0.70
2_C	57_D	0.596	0.70
473_D	477_A	0.596	0.70
343_H	478_A	0.595	0.70
57_D	60_N	0.594	0.70
14_R	18_C	0.593	0.70
151_E	203_N	0.592	0.70
297_T	309_A	0.592	0.70
60_N	98_T	0.592	0.70
278_I	526_Y	0.592	0.70
356_E	363_L	0.591	0.70
90_L	111_K	0.590	0.69
355_P	538_K	0.589	0.69
20_F	40_Y	0.589	0.69
429_E	432_F	0.588	0.69
50_F	65_F	0.587	0.69
426_R	432_F	0.587	0.69
524_T	527_T	0.586	0.69
65_F	74_V	0.585	0.69
94_M	106_H	0.585	0.69
128_W	217_L	0.584	0.69
252_Y	514_L	0.584	0.69
464_L	467_Y	0.583	0.69
254_E	257_A	0.582	0.68
122_M	141_R	0.582	0.68
516_K	528_H	0.581	0.68
392_T	396_P	0.581	0.68
496_V	513_V	0.580	0.68
197_T	206_N	0.579	0.68
35_P	53_L	0.577	0.68
55_I	268_V	0.576	0.68
240_R	243_L	0.576	0.68
456_Y	504_R	0.576	0.68
240_R	498_G	0.576	0.68
86_L	107_L	0.576	0.68
65_F	76_V	0.575	0.67
270_V	287_A	0.574	0.67
357_Q	471_H	0.574	0.67
256_L	514_L	0.573	0.67
421_Q	424_I	0.572	0.67
175_F	571_I	0.571	0.67
249_I	513_V	0.571	0.67
386_F	496_V	0.569	0.67
189_E	471_H	0.568	0.67
144_I	382_G	0.567	0.66
359_Y	362_H	0.566	0.66
381_Q	463_D	0.566	0.66
259_S	489_D	0.566	0.66
346_W	609_T	0.565	0.66
381_Q	474_R	0.565	0.66
460_K	463_D	0.565	0.66
452_P	457_V	0.564	0.66
537_G	541_R	0.564	0.66
84_K	88_A	0.564	0.66
438_N	441_Y	0.563	0.66
409_V	413_E	0.563	0.66
314_W	526_Y	0.563	0.66
41_H	66_L	0.563	0.66
77_N	482_E	0.562	0.66
422_G	425_F	0.562	0.66
85_E	88_A	0.562	0.66
602_M	606_S	0.561	0.66
161_E	349_E	0.561	0.66
308_D	359_Y	0.560	0.65
573_Q	577_I	0.560	0.65
260_V	287_A	0.560	0.65
246_D	250_E	0.559	0.65
142_F	228_W	0.559	0.65
295_T	325_Q	0.559	0.65
107_L	110_E	0.559	0.65
353_C	363_L	0.558	0.65
253_R	518_L	0.557	0.65
9_N	154_H	0.556	0.65
441_Y	445_N	0.556	0.65
583_Y	589_E	0.555	0.65
70_G	130_K	0.555	0.65
62_Q	65_F	0.554	0.65
381_Q	470_W	0.554	0.65
46_V	135_V	0.554	0.65
7_I	155_E	0.553	0.65
398_E	402_W	0.552	0.64
2_C	122_M	0.552	0.64
243_L	499_I	0.551	0.64
81_Y	485_V	0.549	0.64
144_I	470_W	0.548	0.64
281_A	529_R	0.547	0.64
56_L	60_N	0.546	0.64
381_Q	475_I	0.546	0.64
393_T	467_Y	0.546	0.64
241_E	498_G	0.545	0.63
272_L	283_V	0.545	0.63
74_V	116_V	0.544	0.63
260_V	378_L	0.544	0.63
453_W	458_L	0.543	0.63
522_L	527_T	0.543	0.63
449_Q	454_Q	0.543	0.63
129_D	134_K	0.542	0.63
244_H	503_L	0.541	0.63
434_L	437_I	0.541	0.63
513_V	516_K	0.540	0.63
513_V	517_S	0.540	0.63
390_Y	477_A	0.540	0.63
529_R	532_V	0.540	0.63
183_D	191_A	0.540	0.63
258_D	490_H	0.539	0.63
399_N	403_E	0.538	0.62
364_H	483_N	0.537	0.62
249_I	503_L	0.536	0.62
460_K	464_L	0.535	0.62
52_R	57_D	0.535	0.62
451_D	455_S	0.535	0.62
52_R	267_D	0.534	0.62
273_F	481_I	0.534	0.62
9_N	14_R	0.534	0.62
549_H	604_L	0.533	0.62
163_K	347_I	0.533	0.62
456_Y	463_D	0.531	0.61
151_E	215_I	0.530	0.61
420_L	424_I	0.530	0.61
189_E	467_Y	0.529	0.61
9_N	18_C	0.529	0.61
120_I	255_L	0.528	0.61
406_I	413_E	0.528	0.61
518_L	527_T	0.528	0.61
461_Y	465_Q	0.527	0.61
405_F	413_E	0.526	0.61
422_G	426_R	0.525	0.61
411_T	414_M	0.525	0.61
424_I	427_V	0.524	0.60
141_R	227_Y	0.523	0.60
24_K	42_I	0.522	0.60
52_R	390_Y	0.522	0.60
403_E	417_L	0.522	0.60
28_D	31_S	0.520	0.60
559_I	569_S	0.519	0.60
284_A	287_A	0.518	0.60
294_H	373_N	0.518	0.60
95_F	102_E	0.517	0.59
57_D	267_D	0.517	0.59
406_I	409_V	0.515	0.59
379_T	472_E	0.514	0.59
159_A	168_H	0.514	0.59
247_D	251_G	0.514	0.59
473_D	482_E	0.514	0.59
7_I	18_C	0.513	0.59
4_L	30_I	0.513	0.59
500_P	503_L	0.513	0.59
84_K	103_V	0.512	0.59
404_G	412_M	0.512	0.59
54_S	375_K	0.511	0.58
319_L	323_N	0.511	0.58
27_A	31_S	0.511	0.58
548_F	552_K	0.511	0.58
555_N	578_H	0.511	0.58
187_S	191_A	0.510	0.58
82_N	86_L	0.510	0.58
248_L	500_P	0.510	0.58
472_E	485_V	0.510	0.58
35_P	390_Y	0.509	0.58
244_H	250_E	0.509	0.58
228_W	490_H	0.508	0.58
406_I	412_M	0.507	0.58
401_S	405_F	0.507	0.58
75_M	158_F	0.506	0.58
405_F	412_M	0.505	0.58
354_G	381_Q	0.504	0.57
408_S	413_E	0.503	0.57
52_R	268_V	0.503	0.57
54_S	97_T	0.503	0.57
402_W	409_V	0.503	0.57
343_H	361_F	0.503	0.57
276_G	297_T	0.503	0.57
394_L	397_A	0.502	0.57
348_C	474_R	0.502	0.57
145_K	473_D	0.502	0.57
436_P	440_S	0.501	0.57
336_L	546_M	0.501	0.57
152_L	170_H	0.501	0.57
345_L	604_L	0.501	0.57
66_L	130_K	0.500	0.57

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ct9A	2	0.6533	100	0.467	Contact Map
1q15A	3	0.6426	100	0.482	Contact Map
1jgtA	2	0.6332	100	0.492	Contact Map
1ao0A	3	0.5261	100	0.77	Contact Map
1te5A	2	0.2477	100	0.791	Contact Map
1xffA	2	0.2624	100	0.791	Contact Map
1ecfA	4	0.5596	100	0.798	Contact Map
4amvA	2	0.6747	100	0.805	Contact Map
3mdnA	4	0.2209	100	0.821	Contact Map
4zflA	5	0.245	100	0.837	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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