YXAL - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YXAL - Uncharacterized protein YxaL

UniProt:	P42111	Sequences: MVKSFRMKALIAGAAVAAAVSAGAVSDVPAAKVLQPTAAYAAETVFSQNNGASGFLPGRYDVQAMAPAMFNWSRESRFAGNTDGTLKWQNDIRTTPQNGAGAVIDGDGTVYLHSRDGEMKAFNPDGSVKWVTGNLGKTYTQSPVLGTNGVIYLASYDKKIYFIDKETGEILTTVPLSGGPSSETVIGSDGTLYFSTLDNYVHAIKPTSKSTWTERWKLKTNGVVSSVPVLAKNGTVYVGTYNYVFYAINSGTGQVKWSRTTSNAFKGYPVIDKDGNIYAGNQDGQLYAYTSTGSLKWTFPLNGFSSSSPAIDHNGNIYIGSGSGELFSISKNGDMNWSFYTDGPVRTAPLIDAKGTVYFGSDDMKVYAADANGNELWSYQTDSNVVSSPQLAEDGTLYIGSYTKLMAFGK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	410 (332)
Sequences:	1308 (1169)
Seq/√Len:	64.2

ECOLI - YNCE
BACSU - YXAL YWHL YWHK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
177_S	195_S	6.513	1.00
136_G	153_L	5.093	1.00
279_A	289_Y	3.778	1.00
238_V	248_I	3.642	1.00
153_L	157_D	3.540	1.00
177_S	198_D	3.405	1.00
272_D	275_G	3.401	1.00
152_Y	193_Y	3.399	1.00
153_L	163_I	3.165	1.00
152_Y	186_I	3.061	1.00
278_Y	311_I	3.052	1.00
237_Y	277_I	2.995	1.00
197_L	200_Y	2.871	1.00
302_N	319_I	2.802	1.00
278_Y	317_I	2.604	1.00
239_G	266_K	2.559	1.00
280_G	306_S	2.485	1.00
183_E	196_T	2.381	1.00
112_L	145_L	2.371	1.00
177_S	197_L	2.369	1.00
142_S	154_A	2.342	1.00
194_F	236_V	2.310	1.00
136_G	157_D	2.306	1.00
358_Y	368_A	2.293	1.00
237_Y	271_I	2.280	1.00
42_A	76_S	2.267	1.00
194_F	230_L	2.223	1.00
152_Y	160_I	2.215	1.00
221_N	238_V	2.206	1.00
227_V	239_G	2.197	1.00
242_N	246_Y	2.177	1.00
43_E	46_F	2.163	1.00
359_F	369_A	2.147	1.00
113_H	117_G	2.137	1.00
245_F	279_A	2.058	1.00
95_T	113_H	2.008	1.00
136_G	155_S	2.001	1.00
160_I	195_S	1.983	1.00
194_F	203_A	1.961	1.00
112_L	151_I	1.909	1.00
89_Q	92_I	1.837	1.00
55_F	58_G	1.816	1.00
152_Y	184_T	1.810	1.00
319_I	329_I	1.773	1.00
195_S	198_D	1.768	1.00
195_S	204_I	1.740	0.99
152_Y	162_F	1.735	0.99
37_T	41_A	1.728	0.99
177_S	200_Y	1.699	0.99
104_I	111_Y	1.698	0.99
84_G	88_W	1.692	0.99
176_L	195_S	1.680	0.99
184_T	195_S	1.673	0.99
249_N	252_T	1.673	0.99
85_T	88_W	1.665	0.99
185_V	194_F	1.659	0.99
112_L	115_R	1.653	0.99
146_G	186_I	1.620	0.99
42_A	46_F	1.602	0.99
155_S	159_K	1.602	0.99
262_S	283_D	1.598	0.99
194_F	228_P	1.586	0.99
155_S	161_Y	1.578	0.99
136_G	140_T	1.574	0.99
101_G	114_S	1.530	0.99
42_A	49_N	1.506	0.99
59_R	66_A	1.503	0.99
136_G	163_I	1.500	0.98
41_A	45_V	1.471	0.98
320_G	324_G	1.452	0.98
249_N	291_S	1.450	0.98
62_V	65_M	1.447	0.98
161_Y	173_T	1.444	0.98
63_Q	70_F	1.432	0.98
68_A	80_G	1.430	0.98
361_S	364_M	1.410	0.98
95_T	117_G	1.409	0.98
65_M	69_M	1.404	0.98
194_F	201_V	1.399	0.98
38_A	42_A	1.371	0.97
57_P	64_A	1.368	0.97
197_L	240_T	1.367	0.97
286_L	299_F	1.362	0.97
283_D	287_Y	1.351	0.97
55_F	61_D	1.348	0.97
278_Y	288_A	1.347	0.97
361_S	369_A	1.343	0.97
44_T	48_Q	1.335	0.97
44_T	49_N	1.327	0.97
53_S	64_A	1.319	0.97
73_S	77_R	1.314	0.96
146_G	149_G	1.313	0.96
204_I	329_I	1.312	0.96
311_I	317_I	1.306	0.96
99_G	113_H	1.305	0.96
160_I	181_S	1.304	0.96
177_S	204_I	1.300	0.96
237_Y	247_A	1.293	0.96
56_L	60_Y	1.292	0.96
45_V	49_N	1.292	0.96
113_H	123_N	1.253	0.95
230_L	233_N	1.245	0.95
203_A	230_L	1.241	0.95
44_T	47_S	1.236	0.95
35_Q	41_A	1.233	0.95
75_E	78_F	1.230	0.95
112_L	143_P	1.224	0.95
347_T	351_I	1.218	0.95
64_A	67_P	1.215	0.95
47_S	59_R	1.202	0.94
105_D	109_T	1.199	0.94
36_P	41_A	1.184	0.94
42_A	53_S	1.183	0.94
41_A	44_T	1.182	0.94
48_Q	52_A	1.181	0.94
280_G	284_G	1.173	0.93
286_L	319_I	1.169	0.93
61_D	64_A	1.168	0.93
35_Q	42_A	1.163	0.93
72_W	76_S	1.163	0.93
35_Q	38_A	1.148	0.93
36_P	39_A	1.143	0.93
42_A	47_S	1.140	0.92
38_A	54_G	1.129	0.92
79_A	85_T	1.114	0.92
47_S	52_A	1.111	0.91
103_V	112_L	1.107	0.91
112_L	122_F	1.107	0.91
74_R	77_R	1.100	0.91
62_V	69_M	1.099	0.91
55_F	63_Q	1.093	0.91
71_N	77_R	1.092	0.91
160_I	174_V	1.091	0.91
157_D	161_Y	1.090	0.91
63_Q	66_A	1.088	0.91
196_T	225_S	1.080	0.90
69_M	72_W	1.077	0.90
47_S	58_G	1.063	0.90
262_S	279_A	1.060	0.89
57_P	60_Y	1.060	0.89
39_A	71_N	1.059	0.89
62_V	74_R	1.054	0.89
58_G	62_V	1.053	0.89
160_I	184_T	1.048	0.89
136_G	161_Y	1.047	0.89
176_L	204_I	1.046	0.89
63_Q	67_P	1.029	0.88
242_N	248_I	1.025	0.88
47_S	54_G	1.022	0.88
79_A	86_L	1.022	0.88
78_F	81_N	1.021	0.88
82_T	86_L	1.019	0.87
45_V	52_A	1.019	0.87
59_R	63_Q	1.018	0.87
318_Y	357_V	1.010	0.87
39_A	42_A	1.002	0.87
80_G	84_G	0.999	0.86
48_Q	51_G	0.993	0.86
50_N	53_S	0.992	0.86
163_I	204_I	0.991	0.86
62_V	67_P	0.986	0.86
187_G	230_L	0.982	0.85
60_Y	65_M	0.980	0.85
105_D	108_G	0.979	0.85
68_A	71_N	0.978	0.85
55_F	66_A	0.977	0.85
231_A	271_I	0.962	0.84
54_G	58_G	0.961	0.84
69_M	73_S	0.955	0.84
49_N	58_G	0.951	0.84
154_A	181_S	0.946	0.83
309_P	319_I	0.945	0.83
45_V	48_Q	0.943	0.83
46_F	49_N	0.941	0.83
41_A	46_F	0.939	0.83
52_A	55_F	0.938	0.83
67_P	76_S	0.934	0.82
71_N	76_S	0.933	0.82
53_S	75_E	0.933	0.82
51_G	56_L	0.932	0.82
71_N	74_R	0.924	0.82
342_D	359_F	0.924	0.82
272_D	311_I	0.922	0.82
84_G	89_Q	0.919	0.81
39_A	57_P	0.913	0.81
137_K	155_S	0.911	0.81
54_G	59_R	0.910	0.81
201_V	238_V	0.908	0.81
188_S	234_G	0.908	0.81
95_T	99_G	0.906	0.80
52_A	58_G	0.903	0.80
238_V	246_Y	0.899	0.80
43_E	52_A	0.897	0.80
97_Q	110_V	0.893	0.79
66_A	70_F	0.888	0.79
53_S	63_Q	0.883	0.79
72_W	75_E	0.881	0.79
71_N	78_F	0.877	0.78
356_T	360_G	0.875	0.78
52_A	60_Y	0.873	0.78
38_A	45_V	0.872	0.78
281_N	317_I	0.870	0.78
47_S	60_Y	0.870	0.78
56_L	74_R	0.867	0.77
85_T	90_N	0.865	0.77
318_Y	328_S	0.862	0.77
49_N	54_G	0.861	0.77
82_T	87_K	0.858	0.77
70_F	76_S	0.856	0.77
56_L	62_V	0.855	0.76
45_V	59_R	0.853	0.76
45_V	57_P	0.851	0.76
60_Y	63_Q	0.849	0.76
105_D	279_A	0.848	0.76
35_Q	39_A	0.847	0.76
60_Y	67_P	0.847	0.76
56_L	59_R	0.847	0.76
80_G	83_D	0.841	0.75
49_N	59_R	0.841	0.75
361_S	366_V	0.839	0.75
42_A	45_V	0.838	0.75
52_A	57_P	0.835	0.75
81_N	86_L	0.829	0.74
145_L	151_I	0.827	0.74
195_S	200_Y	0.823	0.74
40_Y	47_S	0.823	0.74
59_R	67_P	0.822	0.74
69_M	74_R	0.820	0.73
67_P	70_F	0.818	0.73
64_A	68_A	0.808	0.72
52_A	63_Q	0.805	0.72
44_T	59_R	0.802	0.72
221_N	248_I	0.801	0.72
147_T	186_I	0.799	0.71
358_Y	369_A	0.798	0.71
46_F	50_N	0.798	0.71
79_A	82_T	0.795	0.71
83_D	86_L	0.795	0.71
49_N	52_A	0.793	0.71
359_F	367_Y	0.792	0.71
288_A	311_I	0.791	0.71
155_S	158_K	0.788	0.70
55_F	60_Y	0.786	0.70
57_P	61_D	0.783	0.70
142_S	203_A	0.781	0.70
347_T	352_D	0.780	0.70
198_D	202_H	0.777	0.69
243_Y	269_P	0.776	0.69
50_N	68_A	0.775	0.69
63_Q	69_M	0.772	0.69
40_Y	49_N	0.770	0.69
56_L	65_M	0.769	0.69
62_V	66_A	0.769	0.69
301_L	329_I	0.767	0.68
215_R	240_T	0.766	0.68
153_L	159_K	0.760	0.68
48_Q	70_F	0.756	0.67
135_L	161_Y	0.754	0.67
74_R	78_F	0.753	0.67
289_Y	295_L	0.753	0.67
69_M	77_R	0.751	0.67
41_A	50_N	0.751	0.67
280_G	323_S	0.745	0.66
44_T	60_Y	0.744	0.66
344_P	363_D	0.744	0.66
59_R	64_A	0.742	0.66
55_F	65_M	0.741	0.66
59_R	70_F	0.740	0.66
80_G	85_T	0.738	0.65
123_N	151_I	0.738	0.65
78_F	114_S	0.735	0.65
120_K	143_P	0.735	0.65
221_N	242_N	0.733	0.65
80_G	91_D	0.732	0.65
286_L	310_A	0.731	0.65
345_V	348_A	0.730	0.64
162_F	331_K	0.729	0.64
42_A	54_G	0.728	0.64
143_P	153_L	0.728	0.64
56_L	61_D	0.725	0.64
43_E	47_S	0.725	0.64
55_F	64_A	0.725	0.64
46_F	51_G	0.724	0.64
88_W	92_I	0.721	0.64
52_A	56_L	0.720	0.63
352_D	358_Y	0.719	0.63
85_T	89_Q	0.719	0.63
44_T	54_G	0.718	0.63
49_N	56_L	0.715	0.63
269_P	277_I	0.715	0.63
257_W	260_T	0.714	0.63
53_S	56_L	0.710	0.62
170_I	245_F	0.709	0.62
82_T	88_W	0.709	0.62
217_K	269_P	0.707	0.62
60_Y	69_M	0.706	0.62
177_S	181_S	0.702	0.61
36_P	44_T	0.702	0.61
110_V	114_S	0.702	0.61
346_R	359_F	0.702	0.61
36_P	42_A	0.701	0.61
84_G	91_D	0.699	0.61
84_G	90_N	0.698	0.61
42_A	73_S	0.693	0.60
278_Y	286_L	0.691	0.60
261_T	289_Y	0.690	0.60
195_S	202_H	0.690	0.60
284_G	328_S	0.689	0.60
136_G	159_K	0.689	0.60
51_G	59_R	0.688	0.60
48_Q	55_F	0.684	0.59
36_P	45_V	0.681	0.59
40_Y	54_G	0.678	0.59
66_A	72_W	0.678	0.59
322_G	360_G	0.677	0.59
52_A	62_V	0.677	0.59
60_Y	72_W	0.676	0.59
37_T	66_A	0.674	0.58
151_I	196_T	0.672	0.58
135_L	163_I	0.671	0.58
38_A	41_A	0.669	0.58
86_L	92_I	0.669	0.58
232_K	271_I	0.668	0.58
122_F	145_L	0.668	0.58
185_V	229_V	0.668	0.58
160_I	193_Y	0.667	0.58
117_G	124_P	0.667	0.58
57_P	62_V	0.665	0.57
40_Y	45_V	0.663	0.57
159_K	173_T	0.662	0.57
46_F	60_Y	0.662	0.57
311_I	315_G	0.661	0.57
101_G	105_D	0.660	0.57
40_Y	65_M	0.660	0.57
335_M	338_S	0.659	0.57
54_G	62_V	0.658	0.57
81_N	85_T	0.655	0.56
51_G	61_D	0.654	0.56
56_L	75_E	0.654	0.56
162_F	186_I	0.653	0.56
142_S	155_S	0.652	0.56
40_Y	70_F	0.652	0.56
72_W	80_G	0.651	0.56
86_L	89_Q	0.651	0.56
203_A	216_W	0.651	0.56
35_Q	44_T	0.650	0.56
50_N	55_F	0.649	0.55
55_F	59_R	0.648	0.55
100_A	104_I	0.645	0.55
79_A	87_K	0.642	0.55
58_G	66_A	0.642	0.55
62_V	68_A	0.640	0.54
198_D	204_I	0.638	0.54
205_K	211_T	0.637	0.54
46_F	65_M	0.637	0.54
105_D	113_H	0.635	0.54
310_A	318_Y	0.635	0.54
132_T	155_S	0.633	0.54
87_K	91_D	0.631	0.53
330_S	334_D	0.630	0.53
154_A	195_S	0.629	0.53
53_S	62_V	0.628	0.53
211_T	221_N	0.627	0.53
69_M	76_S	0.627	0.53
179_G	189_D	0.626	0.53
348_A	351_I	0.626	0.53
104_I	117_G	0.625	0.53
73_S	89_Q	0.625	0.53
99_G	114_S	0.625	0.53
55_F	62_V	0.624	0.53
144_V	184_T	0.624	0.53
52_A	64_A	0.621	0.52
53_S	57_P	0.621	0.52
360_G	364_M	0.619	0.52
220_T	248_I	0.616	0.52
42_A	50_N	0.616	0.52
63_Q	76_S	0.615	0.52
133_G	141_Q	0.614	0.51
60_Y	64_A	0.614	0.51
106_G	145_L	0.613	0.51
42_A	68_A	0.611	0.51
54_G	57_P	0.609	0.51
48_Q	59_R	0.607	0.51
148_N	181_S	0.605	0.50
41_A	56_L	0.605	0.50
68_A	76_S	0.604	0.50
95_T	123_N	0.603	0.50
161_Y	170_I	0.602	0.50
73_S	76_S	0.602	0.50
99_G	102_A	0.601	0.50
67_P	71_N	0.601	0.50
38_A	66_A	0.601	0.50
43_E	49_N	0.600	0.50
76_S	92_I	0.600	0.50
113_H	118_E	0.599	0.50
49_N	60_Y	0.599	0.50
220_T	240_T	0.598	0.50
164_D	205_K	0.598	0.50
201_V	228_P	0.597	0.49
212_W	216_W	0.596	0.49
321_S	324_G	0.593	0.49
190_G	202_H	0.593	0.49
356_T	361_S	0.592	0.49
78_F	83_D	0.592	0.49
40_Y	46_F	0.591	0.49
125_D	286_L	0.590	0.49
107_D	195_S	0.589	0.49
85_T	91_D	0.589	0.49
36_P	59_R	0.588	0.48
46_F	57_P	0.587	0.48
326_L	359_F	0.587	0.48
355_G	359_F	0.586	0.48
289_Y	293_G	0.585	0.48
213_T	220_T	0.583	0.48
147_T	190_G	0.583	0.48
67_P	73_S	0.582	0.48
68_A	79_A	0.582	0.48
60_Y	66_A	0.580	0.47
45_V	56_L	0.579	0.47
43_E	61_D	0.577	0.47
54_G	64_A	0.577	0.47
240_T	279_A	0.575	0.47
211_T	288_A	0.575	0.47
318_Y	351_I	0.573	0.47
59_R	68_A	0.572	0.47
44_T	50_N	0.572	0.47
273_K	276_N	0.571	0.46
256_K	259_R	0.570	0.46
104_I	113_H	0.570	0.46
36_P	40_Y	0.568	0.46
348_A	360_G	0.567	0.46
57_P	63_Q	0.567	0.46
316_N	320_G	0.567	0.46
236_V	253_G	0.567	0.46
48_Q	62_V	0.564	0.46
42_A	70_F	0.564	0.46
225_S	250_S	0.563	0.46
162_F	206_P	0.561	0.45
39_A	56_L	0.559	0.45
114_S	118_E	0.559	0.45
36_P	46_F	0.558	0.45
45_V	51_G	0.556	0.45
59_R	74_R	0.553	0.44
201_V	358_Y	0.549	0.44
215_R	222_G	0.547	0.44
268_Y	280_G	0.546	0.44
274_D	288_A	0.546	0.44
228_P	238_V	0.546	0.44
83_D	90_N	0.543	0.43
201_V	243_Y	0.542	0.43
89_Q	96_P	0.542	0.43
44_T	53_S	0.541	0.43
37_T	53_S	0.541	0.43
181_S	200_Y	0.541	0.43
84_G	92_I	0.540	0.43
153_L	161_Y	0.538	0.43
68_A	72_W	0.537	0.43
197_L	220_T	0.537	0.43
203_A	235_T	0.536	0.42
49_N	57_P	0.534	0.42
144_V	152_Y	0.533	0.42
315_G	330_S	0.533	0.42
120_K	124_P	0.533	0.42
44_T	51_G	0.532	0.42
43_E	59_R	0.531	0.42
152_Y	171_L	0.531	0.42
49_N	55_F	0.531	0.42
298_T	321_S	0.530	0.42
186_I	193_Y	0.528	0.42
122_F	164_D	0.526	0.41
264_A	299_F	0.526	0.41
43_E	48_Q	0.525	0.41
318_Y	329_I	0.524	0.41
54_G	68_A	0.523	0.41
37_T	42_A	0.521	0.41
351_I	354_K	0.521	0.41
56_L	63_Q	0.520	0.41
359_F	366_V	0.518	0.40
174_V	186_I	0.516	0.40
63_Q	71_N	0.516	0.40
154_A	160_I	0.515	0.40
339_F	346_R	0.512	0.40
56_L	67_P	0.510	0.40
49_N	63_Q	0.510	0.40
254_Q	294_S	0.508	0.39
54_G	60_Y	0.507	0.39
231_A	273_K	0.506	0.39
169_E	225_S	0.505	0.39
228_P	236_V	0.504	0.39
45_V	68_A	0.503	0.39
63_Q	74_R	0.503	0.39
58_G	65_M	0.503	0.39
44_T	56_L	0.503	0.39
42_A	48_Q	0.503	0.39
43_E	51_G	0.502	0.39
40_Y	58_G	0.502	0.39
202_H	217_K	0.501	0.39
70_F	74_R	0.500	0.38

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1vyhC	1	0.7024	100	0.387	Contact Map
2ymuA	1	0.7902	100	0.41	Contact Map
4wjuA	1	0.9146	100	0.421	Contact Map
1gotB	1	0.7927	100	0.427	Contact Map
5a1uD	1	0.7951	100	0.436	Contact Map
3sfzA	1	0.9902	100	0.437	Contact Map
4lg9A	1	0.7854	100	0.44	Contact Map
4j87A	1	0.6927	100	0.441	Contact Map
4j0xA	1	0.7561	100	0.443	Contact Map
4i79A	2	0.6756	100	0.444	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0114 seconds.