GREMLIN Database
YXAI - Uncharacterized protein YxaI
UniProt: P42108 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 151 (133)
Sequences: 2085 (1639)
Seq/√Len: 142.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
79_L88_L4.6201.00
134_G142_I3.5541.00
131_I138_G2.8841.00
9_I150_Y2.8271.00
130_M139_L2.7221.00
5_A95_L2.7171.00
16_I93_L2.7081.00
116_A143_I2.4961.00
105_V110_G2.4571.00
99_N109_Q2.3921.00
86_G91_K2.3631.00
129_I133_F2.3191.00
105_V146_T2.1861.00
130_M134_G2.0341.00
120_S140_H1.8561.00
136_K147_R1.8461.00
120_S127_G1.8371.00
80_T114_Y1.7541.00
16_I92_I1.6681.00
129_I132_A1.6591.00
30_F34_S1.6071.00
12_L93_L1.5701.00
81_A107_V1.5661.00
14_Y76_Y1.5661.00
7_F131_I1.5181.00
100_E136_K1.4841.00
124_F127_G1.4821.00
6_G9_I1.4811.00
11_F131_I1.4631.00
98_V149_V1.4321.00
3_K150_Y1.3881.00
98_V147_R1.3551.00
81_A110_G1.3541.00
99_N106_S1.3441.00
100_E147_R1.3371.00
80_T90_K1.3351.00
99_N103_E1.2941.00
120_S138_G1.2361.00
123_I139_L1.2331.00
7_F132_A1.2321.00
19_I22_S1.2291.00
77_G111_I1.2221.00
112_G115_F1.2181.00
84_M91_K1.1590.99
112_G143_I1.1560.99
110_G114_Y1.1230.99
80_T117_Y1.1160.99
79_L91_K1.1120.99
73_V111_I1.1110.99
77_G110_G1.1050.99
85_Q98_V1.0980.99
106_S109_Q1.0960.99
117_Y120_S1.0880.99
4_P147_R1.0860.99
16_I20_I1.0770.99
85_Q96_K1.0760.99
108_G112_G1.0750.99
75_Y80_T1.0610.99
80_T138_G1.0570.99
19_I23_V1.0570.99
120_S128_F1.0530.99
86_G95_L1.0480.99
6_G132_A1.0470.99
120_S124_F1.0410.99
80_T97_V1.0260.99
114_Y117_Y1.0080.99
15_F19_I1.0040.99
22_S26_Y0.9900.98
80_T140_H0.9900.98
4_P7_F0.9840.98
13_A90_K0.9830.98
119_L123_I0.9690.98
58_T62_L0.9610.98
111_I115_F0.9580.98
142_I147_R0.9500.98
38_A41_V0.9270.98
117_Y140_H0.9220.97
77_G107_V0.9080.97
72_S76_Y0.9020.97
109_Q112_G0.9010.97
107_V111_I0.8960.97
78_L83_K0.8930.97
8_W132_A0.8870.97
39_G42_A0.8700.96
11_F14_Y0.8630.96
76_Y87_T0.8620.96
117_Y128_F0.8590.96
9_I12_L0.8580.96
9_I95_L0.8330.95
123_I127_G0.8310.95
76_Y80_T0.8310.95
74_L107_V0.8290.95
116_A140_H0.8270.95
107_V110_G0.8230.95
77_G87_T0.8190.95
74_L78_L0.8190.95
100_E145_K0.8190.95
73_V114_Y0.8060.94
75_Y78_L0.8020.94
137_K143_I0.7980.94
97_V110_G0.7950.94
136_K142_I0.7830.94
116_A120_S0.7810.94
29_L33_N0.7810.94
24_P71_I0.7770.93
33_N37_V0.7750.93
120_S123_I0.7650.93
6_G131_I0.7570.92
88_L92_I0.7550.92
77_G115_F0.7480.92
130_M142_I0.7460.92
116_A127_G0.7430.92
6_G137_K0.7420.92
17_D89_G0.7420.92
73_V77_G0.7380.91
79_L84_M0.7370.91
9_I93_L0.7360.91
121_G124_F0.7350.91
127_G130_M0.7340.91
16_I90_K0.7280.91
60_A63_P0.7250.91
120_S125_Y0.7220.91
140_H144_C0.7220.91
14_Y18_G0.7100.90
33_N36_F0.7100.90
92_I126_I0.7070.90
58_T61_F0.7070.90
99_N145_K0.7050.90
98_V104_R0.7020.89
99_N105_V0.7000.89
26_Y39_G0.6900.89
67_I71_I0.6880.88
86_G110_G0.6870.88
77_G81_A0.6850.88
8_W15_F0.6840.88
7_F138_G0.6840.88
79_L83_K0.6800.88
127_G139_L0.6720.87
9_I149_V0.6680.87
22_S31_I0.6650.87
95_L148_V0.6620.86
79_L86_G0.6540.86
37_V64_T0.6540.86
75_Y81_A0.6530.86
40_A43_T0.6470.85
40_A70_V0.6450.85
25_S36_F0.6410.85
123_I126_I0.6370.84
75_Y88_L0.6350.84
121_G125_Y0.6350.84
75_Y139_L0.6330.84
27_I31_I0.6320.84
126_I130_M0.6310.84
132_A138_G0.6310.84
135_E150_Y0.6310.84
147_R150_Y0.6280.83
23_V92_I0.6260.83
127_G131_I0.6260.83
61_F64_T0.6250.83
126_I129_I0.6200.83
90_K148_V0.6150.82
115_F120_S0.6110.82
33_N64_T0.6070.81
39_G62_L0.6000.81
64_T68_M0.5980.80
36_F60_A0.5970.80
116_A128_F0.5960.80
75_Y87_T0.5950.80
90_K97_V0.5930.80
31_I34_S0.5900.79
28_I67_I0.5870.79
133_F142_I0.5830.79
126_I139_L0.5820.78
68_M132_A0.5750.78
85_Q104_R0.5740.78
5_A9_I0.5710.77
26_Y60_A0.5710.77
26_Y30_F0.5690.77
97_V105_V0.5680.77
23_V62_L0.5680.77
4_P137_K0.5660.77
20_I88_L0.5640.76
116_A144_C0.5570.75
34_S37_V0.5550.75
39_G63_P0.5540.75
121_G128_F0.5450.74
85_Q88_L0.5420.73
114_Y138_G0.5420.73
30_F38_A0.5280.72
105_V109_Q0.5280.72
104_R134_G0.5270.71
36_F39_G0.5270.71
35_V40_A0.5190.70
32_I63_P0.5180.70
90_K144_C0.5100.69
117_Y124_F0.5100.69
138_G144_C0.5050.68
9_I94_G0.5030.68
87_T150_Y0.5000.67
80_T134_G0.5000.67
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3dh4A 3 0.543 3.3 0.946 Contact Map
3kijA 1 0.4371 2.5 0.949 Contact Map
3cniA 2 0.3179 2.4 0.95 Contact Map
3g9kS 1 0.351 2 0.952 Contact Map
2f9sA 1 0.4172 1.9 0.952 Contact Map
2ot8C 1 0.0596 1.9 0.953 Contact Map
2cvbA 1 0.457 1.9 0.953 Contact Map
2cw3A 2 0 1.8 0.953 Contact Map
4tr3A 1 0.5232 1.7 0.954 Contact Map
3gqhA 3 0.4768 1.7 0.954 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0066 seconds.