GREMLIN Database
YTKA - Uncharacterized protein YtkA
UniProt: P40768 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 145 (131)
Sequences: 266 (235)
Seq/√Len: 20.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
36_V54_A4.4321.00
49_S97_E3.1741.00
103_D128_G3.0460.99
58_Y115_K2.8260.99
34_L58_Y2.7240.99
68_E113_T2.6900.98
32_E58_Y2.6830.98
34_L119_S2.4460.97
52_Y96_L2.3890.97
64_T88_K2.3460.96
79_K82_S2.2510.95
65_D114_A2.2210.95
38_L52_Y2.1890.95
38_L112_V2.1470.94
74_W109_Q2.1070.93
54_A71_F2.0550.92
38_L110_S2.0500.92
109_Q122_T1.9420.90
82_S109_Q1.8730.88
55_A62_A1.8720.88
75_K102_E1.8330.87
111_H118_H1.7960.86
74_W81_A1.7150.83
57_S115_K1.6640.81
74_W128_G1.6490.81
41_P123_L1.6080.79
65_D115_K1.5320.76
72_E111_H1.4790.73
66_A69_V1.4630.72
108_V112_V1.4600.72
114_A118_H1.4480.71
32_E59_G1.3500.66
110_S121_P1.3450.65
107_T122_T1.3310.65
38_L44_V1.2960.62
30_T96_L1.2660.61
15_L21_G1.2470.59
88_K93_V1.2360.59
63_V115_K1.2350.59
36_V121_P1.2110.57
86_K96_L1.1760.55
21_G46_P1.1710.55
86_K127_V1.1650.54
33_V58_Y1.1550.53
10_F17_G1.1360.52
54_A110_S1.1240.51
74_W107_T1.1240.51
23_S84_M1.1200.51
66_A114_A1.1180.51
81_A109_Q1.1020.50
13_L23_S1.1020.50
15_L102_E1.0710.48
82_S98_T1.0500.47
54_A109_Q1.0460.46
36_V65_D1.0450.46
38_L123_L1.0430.46
5_L61_E1.0360.46
112_V117_Q1.0230.45
5_L99_T1.0210.45
96_L100_F1.0150.44
32_E53_E1.0140.44
83_Q109_Q0.9970.43
44_V127_V0.9910.43
35_D119_S0.9900.43
19_G40_G0.9890.43
56_V72_E0.9670.41
68_E114_A0.9660.41
105_V130_A0.9650.41
84_M96_L0.9490.40
99_T125_V0.9360.39
113_T120_M0.9230.38
56_V114_A0.9180.38
113_T117_Q0.9040.37
36_V110_S0.9000.37
11_S16_N0.9000.37
34_L113_T0.8690.35
126_Q131_D0.8690.35
51_A64_T0.8590.35
72_E118_H0.8540.34
68_E115_K0.8530.34
60_D89_Q0.8490.34
109_Q113_T0.8480.34
13_L32_E0.8440.34
59_G65_D0.8370.33
3_K11_S0.8250.33
2_K39_T0.8230.32
8_L12_A0.8230.32
36_V118_H0.8230.32
34_L115_K0.8190.32
36_V119_S0.8130.32
94_Y114_A0.8060.32
14_L40_G0.8000.31
76_E103_D0.7980.31
17_G90_E0.7920.31
76_E126_Q0.7910.31
103_D107_T0.7840.30
30_T60_D0.7840.30
54_A107_T0.7820.30
21_G28_A0.7810.30
56_V113_T0.7800.30
73_V98_T0.7780.30
47_G68_E0.7620.29
11_S60_D0.7590.29
52_Y100_F0.7590.29
30_T58_Y0.7520.29
57_S83_Q0.7520.29
15_L49_S0.7490.28
3_K116_K0.7490.28
52_Y127_V0.7480.28
4_M8_L0.7470.28
103_D130_A0.7470.28
66_A94_Y0.7390.28
19_G131_D0.7360.28
47_G95_R0.7350.28
15_L34_L0.7310.27
33_V52_Y0.7240.27
85_F101_K0.7200.27
44_V50_A0.7140.27
62_A75_K0.7130.26
105_V128_G0.7120.26
46_P75_K0.7090.26
3_K87_V0.7050.26
36_V114_A0.7000.26
15_L37_K0.6990.26
51_A108_V0.6960.26
38_L58_Y0.6940.26
8_L47_G0.6910.25
19_G70_E0.6860.25
56_V115_K0.6810.25
88_K128_G0.6770.25
72_E114_A0.6740.25
63_V68_E0.6730.24
10_F45_N0.6710.24
83_Q111_H0.6680.24
81_A125_V0.6650.24
52_Y95_R0.6610.24
17_G42_E0.6540.24
54_A121_P0.6530.24
46_P128_G0.6510.23
55_A84_M0.6500.23
90_E97_E0.6480.23
77_G105_V0.6420.23
9_L54_A0.6410.23
32_E55_A0.6370.23
110_S123_L0.6360.23
86_K102_E0.6350.23
14_L35_D0.6330.23
53_E59_G0.6330.23
117_Q127_V0.6310.23
76_E131_D0.6310.23
28_A84_M0.6290.22
16_N26_N0.6260.22
89_Q93_V0.6250.22
72_E94_Y0.6210.22
58_Y107_T0.6210.22
113_T118_H0.6200.22
44_V125_V0.6200.22
8_L14_L0.6130.22
2_K126_Q0.6120.22
18_C120_M0.6060.21
26_N64_T0.6050.21
12_A55_A0.6040.21
55_A86_K0.6020.21
47_G98_T0.6010.21
45_N81_A0.5990.21
17_G89_Q0.5960.21
105_V124_K0.5860.21
38_L49_S0.5850.20
60_D126_Q0.5820.20
21_G116_K0.5810.20
22_E25_A0.5770.20
30_T37_K0.5760.20
45_N48_E0.5760.20
62_A92_G0.5630.20
109_Q112_V0.5610.19
4_M55_A0.5600.19
55_A117_Q0.5510.19
36_V53_E0.5510.19
34_L117_Q0.5420.19
53_E99_T0.5390.19
22_E51_A0.5360.18
43_K60_D0.5360.18
71_F92_G0.5330.18
88_K91_K0.5300.18
82_S129_D0.5210.18
2_K53_E0.5190.18
4_M12_A0.5120.18
14_L128_G0.5110.17
10_F108_V0.5110.17
83_Q124_K0.5090.17
53_E93_V0.5080.17
59_G87_V0.5050.17
27_T90_E0.5030.17
6_V42_E0.5020.17
26_N76_E0.5010.17
6_V91_K0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4lm8A 1 0.731 96 0.871 Contact Map
3pmqA 1 0.7448 96 0.871 Contact Map
4e9lA 1 0.8276 95.4 0.876 Contact Map
3zbiC 1 0.1931 95.3 0.878 Contact Map
2l0dA 1 0.7241 94.5 0.883 Contact Map
3iduA 1 0.7517 93.9 0.886 Contact Map
2kutA 1 0.7103 93.3 0.889 Contact Map
3c75A 1 0.6414 91.8 0.894 Contact Map
4cdgC 1 0.669 89.8 0.898 Contact Map
4lmhA 3 0.7379 89 0.9 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0066 seconds.