GREMLIN Database
YUXK - Uncharacterized protein YuxK
UniProt: P40761 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 137 (129)
Sequences: 1019 (765)
Seq/√Len: 67.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
74_K108_S5.3201.00
34_G134_R3.1561.00
25_Q125_M2.7671.00
67_E80_K2.7661.00
75_S103_R2.5761.00
63_F81_V2.5101.00
93_V96_F2.1801.00
26_F30_R2.1271.00
109_F117_W1.9951.00
11_L81_V1.9571.00
11_L27_I1.9161.00
11_L36_I1.9061.00
16_V115_Y1.9021.00
76_T100_K1.8591.00
19_L110_I1.8301.00
24_V38_F1.8261.00
36_I65_F1.8141.00
75_S104_D1.8121.00
8_N37_S1.7751.00
98_V101_P1.7351.00
76_T103_R1.7301.00
76_T96_F1.7271.00
21_N121_K1.5640.99
64_V73_T1.5630.99
115_Y119_G1.5520.99
65_F80_K1.5380.99
35_L84_H1.5320.99
105_M109_F1.5260.99
49_L66_I1.5200.99
125_M131_I1.5180.99
47_Q60_F1.5040.99
83_R93_V1.5030.99
28_I131_I1.4840.99
86_R90_R1.4680.99
72_Y80_K1.4680.99
87_G90_R1.4490.98
23_A82_F1.4160.98
36_I84_H1.4100.98
13_F18_N1.3860.98
98_V102_V1.3830.98
87_G91_L1.3550.97
83_R96_F1.3450.97
79_I103_R1.3140.97
12_L41_L1.3000.97
12_L66_I1.2760.96
27_I36_I1.2580.96
19_L132_K1.2580.96
39_T45_T1.2560.96
9_R67_E1.2010.95
34_G37_S1.1760.94
95_F106_V1.1690.94
34_G133_K1.1470.94
29_K125_M1.1450.93
109_F113_N1.1440.93
28_I135_F1.1320.93
18_N121_K1.1260.93
12_L46_G1.1110.92
62_S74_K1.0870.92
19_L118_F1.0860.92
47_Q57_T1.0680.91
10_V49_L1.0450.90
32_P86_R1.0380.90
88_P91_L1.0200.89
98_V106_V1.0140.88
43_S46_G1.0070.88
27_I82_F0.9900.87
101_P105_M0.9640.86
88_P92_F0.9620.86
48_S52_K0.9580.85
12_L64_V0.9550.85
13_F24_V0.9540.85
125_M135_F0.9510.85
46_G54_G0.9500.85
128_S131_I0.9360.84
36_I81_V0.9350.84
47_Q51_K0.9330.84
78_A82_F0.9310.84
10_V67_E0.9290.84
49_L53_S0.9280.84
64_V136_L0.9050.82
129_P133_K0.8890.81
115_Y120_K0.8850.81
98_V103_R0.8840.80
44_E47_Q0.8790.80
9_R65_F0.8770.80
9_R37_S0.8660.79
79_I95_F0.8610.79
113_N117_W0.8590.79
14_D17_C0.8560.78
38_F134_R0.8560.78
19_L131_I0.8450.77
9_R84_H0.8440.77
18_N24_V0.8380.77
55_L60_F0.8280.76
46_G55_L0.8250.76
115_Y118_F0.8190.75
12_L51_K0.8110.74
25_Q29_K0.8000.73
79_I93_V0.7990.73
9_R35_L0.7970.73
26_F89_W0.7870.72
14_D20_C0.7850.72
65_F84_H0.7830.72
45_T48_S0.7820.72
10_V45_T0.7750.71
106_V110_I0.7630.70
40_S43_S0.7570.69
18_N21_N0.7520.69
95_F98_V0.7500.69
79_I106_V0.7450.68
46_G51_K0.7390.67
25_Q131_I0.7380.67
31_D86_R0.7270.66
76_T80_K0.7220.66
65_F135_F0.7190.65
16_V122_N0.7190.65
38_F63_F0.7090.64
102_V105_M0.7070.64
17_C20_C0.7060.64
67_E84_H0.7060.64
37_S49_L0.7040.64
29_K32_P0.6920.62
21_N25_Q0.6850.62
126_L131_I0.6830.61
31_D36_I0.6820.61
80_K83_R0.6760.60
83_R91_L0.6730.60
57_T60_F0.6700.60
11_L42_Q0.6660.59
80_K93_V0.6580.58
11_L31_D0.6560.58
12_L63_F0.6530.58
15_G24_V0.6520.58
12_L39_T0.6510.58
128_S132_K0.6450.57
46_G113_N0.6450.57
53_S71_V0.6360.56
53_S66_I0.6330.56
86_R91_L0.6330.56
63_F78_A0.6270.55
76_T79_I0.6270.55
31_D34_G0.6260.55
12_L43_S0.6230.54
23_A63_F0.6150.53
13_F62_S0.6090.53
39_T43_S0.5990.51
25_Q30_R0.5940.51
109_F112_K0.5930.51
46_G49_L0.5920.51
111_A115_Y0.5840.50
23_A27_I0.5820.49
24_V135_F0.5800.49
94_L101_P0.5800.49
79_I121_K0.5800.49
36_I53_S0.5790.49
61_D78_A0.5790.49
70_Q101_P0.5780.49
105_M112_K0.5750.49
54_G86_R0.5700.48
90_R93_V0.5690.48
18_N117_W0.5630.47
60_F63_F0.5610.47
27_I81_V0.5600.47
33_D86_R0.5510.46
34_G131_I0.5490.46
18_N41_L0.5470.45
52_K66_I0.5390.44
70_Q83_R0.5370.44
97_A102_V0.5360.44
50_L60_F0.5340.44
19_L117_W0.5330.44
37_S57_T0.5330.44
74_K104_D0.5320.44
38_F131_I0.5320.44
75_S79_I0.5300.43
48_S51_K0.5300.43
41_L64_V0.5280.43
30_R89_W0.5270.43
95_F126_L0.5260.43
101_P108_S0.5230.43
19_L119_G0.5190.42
29_K105_M0.5190.42
8_N34_G0.5190.42
24_V63_F0.5170.42
43_S75_S0.5160.42
63_F75_S0.5140.41
49_L69_G0.5140.41
66_I71_V0.5100.41
118_F136_L0.5080.41
26_F98_V0.5080.41
124_C127_P0.5050.40
12_L75_S0.5040.40
33_D70_Q0.5030.40
40_S46_G0.5000.40
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4o32A 1 0.5912 76.8 0.915 Contact Map
2vimA 1 0.6131 74.6 0.916 Contact Map
2j23A 1 0.6569 72.4 0.918 Contact Map
2oe3A 2 0.6058 70.2 0.919 Contact Map
3f3qA 1 0.6496 69.6 0.919 Contact Map
1gh2A 1 0.6204 68.7 0.92 Contact Map
2fwhA 1 0.6058 68.6 0.92 Contact Map
2pptA 2 0.6642 67.6 0.92 Contact Map
1w4vA 2 0.6204 67.1 0.92 Contact Map
1zmaA 1 0.5985 65.6 0.921 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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