GREMLIN Database
PBPD - Penicillin-binding protein 4
UniProt: P40750 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 624 (572)
Sequences: 8188 (5623)
Seq/√Len: 235.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
196_K205_E4.7781.00
187_G197_P4.1331.00
247_D251_K3.9761.00
240_K250_L3.8181.00
246_T249_E3.7951.00
496_T592_G3.7471.00
583_V592_G3.3901.00
519_D523_K3.3221.00
86_E90_Q3.2151.00
354_V591_M3.1741.00
434_V444_Y3.1421.00
354_V619_T3.0491.00
229_K233_E2.8901.00
240_K247_D2.8701.00
339_M350_G2.8471.00
545_K585_L2.7591.00
507_S534_Q2.7551.00
88_V186_V2.6111.00
187_G198_L2.5731.00
99_H107_D2.4621.00
101_Y167_N2.4491.00
357_H590_T2.4381.00
237_K254_V2.4351.00
110_G113_R2.4061.00
402_Q459_K2.3761.00
61_R328_D2.3741.00
417_C422_C2.3441.00
250_L254_V2.3361.00
276_V326_A2.3281.00
165_T168_E2.3191.00
59_Y322_K2.3151.00
90_Q244_V2.3091.00
86_E89_K2.2711.00
356_N359_T2.2541.00
81_F89_K2.2211.00
204_G256_Q2.2171.00
80_P83_K2.2131.00
203_V245_I2.1841.00
352_A619_T2.1641.00
437_D546_K2.1601.00
438_T442_N2.1591.00
60_D64_S2.1491.00
81_F171_E2.1041.00
361_Q512_H2.1021.00
324_Y516_K2.0741.00
497_K511_S2.0701.00
95_S234_R2.0621.00
57_Y65_L2.0581.00
361_Q515_T2.0501.00
89_K167_N2.0481.00
362_I513_A2.0311.00
81_F167_N1.9821.00
87_E206_M1.9741.00
85_P198_L1.9611.00
437_D550_S1.9521.00
208_F228_T1.9451.00
363_I589_Y1.9231.00
335_V352_A1.9181.00
87_E90_Q1.9111.00
98_R238_G1.9061.00
341_S618_G1.8981.00
356_N363_I1.8911.00
117_S126_Q1.8901.00
497_K508_Y1.8661.00
546_K549_S1.8511.00
398_P463_Y1.8441.00
401_E466_P1.8291.00
83_K199_K1.8231.00
378_R598_D1.8191.00
386_P490_M1.8111.00
103_H161_E1.7831.00
237_K250_L1.7711.00
431_Y444_Y1.7661.00
393_L498_A1.7651.00
238_G241_D1.7571.00
215_N218_L1.7531.00
236_L250_L1.7491.00
183_V192_F1.7481.00
203_V253_A1.7451.00
505_S542_M1.7421.00
502_F544_L1.7331.00
390_I464_I1.7161.00
410_T433_T1.7161.00
88_V206_M1.7151.00
426_Y607_H1.7131.00
462_S466_P1.7061.00
492_P592_G1.6991.00
95_S238_G1.6981.00
59_Y324_Y1.6931.00
92_F210_C1.6921.00
356_N361_Q1.6851.00
98_R242_A1.6741.00
197_P200_S1.6731.00
94_T244_V1.6611.00
407_T547_L1.6581.00
278_D281_T1.6581.00
452_L460_A1.6531.00
407_T543_Q1.6491.00
495_M583_V1.6421.00
93_L101_Y1.6331.00
353_A492_P1.6271.00
57_Y322_K1.6211.00
92_F179_F1.6171.00
94_T242_A1.6121.00
238_G242_A1.6051.00
392_P502_F1.6041.00
322_K518_T1.5951.00
400_I547_L1.5801.00
136_S160_L1.5761.00
353_A493_L1.5661.00
569_G582_F1.5651.00
411_I454_R1.5631.00
333_N337_A1.5501.00
568_G585_L1.5481.00
121_D125_D1.5481.00
113_R126_Q1.5331.00
61_R363_I1.5171.00
337_A622_A1.5141.00
279_E513_A1.5081.00
536_F541_N1.4801.00
617_K621_Q1.4761.00
79_V84_I1.4751.00
352_A591_M1.4741.00
397_G502_F1.4651.00
224_H227_Y1.4641.00
389_S495_M1.4631.00
88_V92_F1.4611.00
283_L287_S1.4591.00
355_I496_T1.4581.00
191_Q195_S1.4561.00
441_K550_S1.4531.00
459_K462_S1.4531.00
92_F213_P1.4481.00
616_W620_L1.4431.00
331_M363_I1.4341.00
201_L206_M1.4281.00
177_I213_P1.4281.00
276_V327_L1.4201.00
178_Y182_G1.4191.00
240_K245_I1.4181.00
164_Y172_A1.4181.00
439_A447_P1.3871.00
438_T441_K1.3871.00
397_G540_T1.3841.00
452_L457_I1.3841.00
64_S329_P1.3821.00
89_K101_Y1.3811.00
424_Q428_N1.3811.00
202_T256_Q1.3801.00
81_F84_I1.3781.00
147_F151_L1.3681.00
412_D433_T1.3671.00
334_Q338_Q1.3651.00
394_L482_A1.3561.00
427_N431_Y1.3531.00
99_H102_E1.3531.00
552_V567_I1.3501.00
397_G536_F1.3501.00
524_T527_K1.3441.00
500_T590_T1.3441.00
91_I239_L1.3421.00
179_F186_V1.3371.00
567_I586_T1.3371.00
550_S554_S1.3371.00
441_K554_S1.3331.00
509_T532_A1.3311.00
471_K494_E1.3211.00
81_F101_Y1.3201.00
463_Y467_Y1.3101.00
237_K241_D1.3081.00
32_K36_S1.3051.00
401_E540_T1.2941.00
168_E171_E1.2881.00
204_G253_A1.2871.00
579_D594_W1.2791.00
245_I250_L1.2741.00
436_L451_M1.2731.00
226_D230_S1.2721.00
80_P171_E1.2571.00
400_I543_Q1.2571.00
84_I88_V1.2531.00
312_R315_T1.2501.00
279_E283_L1.2491.00
334_Q622_A1.2481.00
595_V615_I1.2471.00
233_E254_V1.2471.00
247_D250_L1.2441.00
505_S538_V1.2431.00
591_M619_T1.2421.00
516_K527_K1.2391.00
508_Y533_T1.2381.00
112_V115_T1.2381.00
335_V619_T1.2371.00
434_V447_P1.2371.00
518_T524_T1.2331.00
444_Y447_P1.2291.00
79_V198_L1.2271.00
87_E203_V1.2261.00
376_F382_A1.2241.00
65_L68_E1.2231.00
106_F154_L1.2231.00
355_I590_T1.2211.00
545_K568_G1.2181.00
128_A137_R1.2171.00
401_E463_Y1.2171.00
453_D479_L1.2161.00
397_G463_Y1.2161.00
227_Y230_S1.2141.00
480_P485_G1.2091.00
107_D110_G1.2091.00
352_A593_V1.2081.00
534_Q538_V1.2051.00
435_T438_T1.2051.00
411_I447_P1.2011.00
335_V366_S1.1971.00
417_C420_D1.1971.00
225_F229_K1.1961.00
502_F585_L1.1931.00
181_N220_D1.1931.00
397_G544_L1.1931.00
553_K561_Y1.1901.00
251_K255_K1.1851.00
240_K254_V1.1831.00
84_I89_K1.1801.00
393_L464_I1.1791.00
399_Y451_M1.1761.00
339_M352_A1.1751.00
251_K254_V1.1651.00
135_L172_A1.1641.00
331_M364_A1.1611.00
248_K252_K1.1611.00
446_T450_R1.1601.00
203_V236_L1.1591.00
337_A341_S1.1591.00
336_V340_N1.1571.00
324_Y518_T1.1521.00
358_Q588_T1.1521.00
384_R579_D1.1501.00
549_S566_Y1.1491.00
504_N509_T1.1451.00
565_P588_T1.1421.00
452_L482_A1.1401.00
492_P496_T1.1351.00
545_K548_M1.1301.00
124_I145_R1.1281.00
405_A454_R1.1271.00
365_L377_N1.1241.00
249_E252_K1.1221.00
276_V280_F1.1221.00
196_K200_S1.1211.00
467_Y501_T1.1201.00
458_Q477_Y1.1131.00
60_D329_P1.1121.00
401_E537_S1.1091.00
148_S152_T1.1081.00
99_H103_H1.1061.00
218_L227_Y1.0971.00
567_I616_W1.0901.00
448_A451_M1.0871.00
421_Y449_I1.0841.00
237_K240_K1.0841.00
496_T583_V1.0801.00
377_N380_Y1.0721.00
280_F325_T1.0701.00
469_F490_M1.0681.00
111_M133_Q1.0681.00
321_V525_L1.0671.00
485_G489_G1.0661.00
584_G616_W1.0651.00
336_V366_S1.0651.00
405_A436_L1.0621.00
111_M128_A1.0621.00
467_Y536_F1.0601.00
436_L547_L1.0601.00
99_H109_M1.0581.00
393_L467_Y1.0571.00
159_Q163_K1.0571.00
61_R361_Q1.0551.00
414_S450_R1.0541.00
174_L186_V1.0511.00
591_M620_L1.0481.00
58_M69_I1.0481.00
178_Y184_Y1.0441.00
338_Q618_G1.0431.00
108_F112_V1.0411.00
87_E249_E1.0391.00
458_Q462_S1.0341.00
416_F450_R1.0341.00
121_D124_I1.0261.00
507_S532_A1.0231.00
58_M66_V1.0211.00
503_G585_L1.0161.00
386_P390_I1.0151.00
430_T446_T1.0131.00
595_V612_Q1.0131.00
353_A365_L1.0131.00
315_T319_D1.0101.00
278_D282_Q1.0101.00
326_A361_Q1.0101.00
92_F174_L1.0081.00
88_V174_L1.0071.00
385_Q574_S1.0061.00
115_T118_N1.0041.00
56_S323_I1.0031.00
463_Y466_P1.0031.00
405_A409_S1.0021.00
344_P347_D1.0021.00
557_G560_A1.0021.00
452_L481_A1.0011.00
339_M366_S1.0001.00
440_F448_A0.9991.00
427_N444_Y0.9971.00
400_I544_L0.9951.00
394_L460_A0.9951.00
18_P22_F0.9931.00
331_M619_T0.9921.00
204_G232_Q0.9881.00
541_N545_K0.9871.00
406_T409_S0.9861.00
118_N121_D0.9841.00
411_I436_L0.9811.00
554_S558_K0.9811.00
81_F170_L0.9801.00
252_K256_Q0.9801.00
211_A228_T0.9791.00
279_E365_L0.9771.00
112_V116_A0.9751.00
124_I147_F0.9731.00
550_S553_K0.9731.00
463_Y536_F0.9671.00
187_G191_Q0.9631.00
91_I210_C0.9631.00
159_Q162_K0.9611.00
516_K524_T0.9611.00
466_P533_T0.9561.00
357_H589_Y0.9551.00
396_Y448_A0.9531.00
353_A496_T0.9521.00
136_S140_Y0.9521.00
541_N544_L0.9511.00
22_F26_A0.9481.00
78_L171_E0.9481.00
118_N124_I0.9451.00
117_S125_D0.9441.00
342_K618_G0.9431.00
551_V557_G0.9391.00
342_K615_I0.9341.00
214_N219_Y0.9321.00
93_L244_V0.9321.00
97_D103_H0.9301.00
89_K170_L0.9301.00
275_Y280_F0.9291.00
397_G467_Y0.9281.00
405_A451_M0.9271.00
116_A120_K0.9231.00
118_N147_F0.9221.00
335_V364_A0.9211.00
580_M612_Q0.9201.00
229_K232_Q0.9191.00
117_S121_D0.9181.00
461_F465_E0.9181.00
357_H503_G0.9171.00
33_Q37_L0.9161.00
151_L155_A0.9151.00
42_D45_I0.9121.00
502_F545_K0.9111.00
354_V589_Y0.9031.00
355_I511_S0.8991.00
512_H528_W0.8991.00
389_S583_V0.8981.00
370_N373_K0.8960.99
446_T449_I0.8950.99
412_D450_R0.8950.99
137_R143_H0.8950.99
492_P581_W0.8940.99
362_I493_L0.8930.99
413_A431_Y0.8920.99
461_F477_Y0.8900.99
593_V615_I0.8900.99
132_T161_E0.8880.99
111_M154_L0.8870.99
455_V459_K0.8870.99
552_V557_G0.8850.99
198_L201_L0.8850.99
64_S330_Y0.8850.99
63_G515_T0.8840.99
411_I451_M0.8840.99
501_T508_Y0.8830.99
462_S465_E0.8830.99
491_T494_E0.8820.99
434_V439_A0.8810.99
85_P88_V0.8800.99
490_M495_M0.8780.99
283_L286_E0.8740.99
324_Y515_T0.8710.99
552_V582_F0.8700.99
276_V513_A0.8690.99
413_A432_G0.8670.99
331_M354_V0.8670.99
440_F547_L0.8650.99
59_Y65_L0.8620.99
455_V460_A0.8600.99
29_K32_K0.8600.99
580_M606_L0.8590.99
95_S231_R0.8570.99
558_K561_Y0.8560.99
328_D331_M0.8530.99
413_A430_T0.8530.99
29_K33_Q0.8530.99
90_Q101_Y0.8500.99
609_I613_L0.8410.99
77_V187_G0.8400.99
85_P206_M0.8390.99
26_A30_E0.8380.99
431_Y442_N0.8380.99
138_N177_I0.8360.99
279_E282_Q0.8330.99
350_G615_I0.8320.99
549_S553_K0.8290.99
95_S214_N0.8280.99
329_P333_N0.8270.99
449_I483_L0.8260.99
161_E169_I0.8250.99
92_F186_V0.8230.99
77_V191_Q0.8210.99
161_E166_K0.8210.99
181_N192_F0.8200.99
131_I177_I0.8180.99
108_F111_M0.8180.99
537_S540_T0.8180.99
456_G459_K0.8160.99
118_N126_Q0.8120.99
390_I394_L0.8120.99
245_I249_E0.8120.99
548_M585_L0.8110.99
405_A411_I0.8090.99
104_K108_F0.8090.99
552_V569_G0.8090.99
452_L479_L0.8090.99
431_Y434_V0.8060.99
89_K93_L0.8060.99
275_Y278_D0.8040.99
400_I540_T0.8020.99
349_Q378_R0.7980.99
461_F481_A0.7970.99
469_F498_A0.7950.99
492_P583_V0.7950.99
415_K430_T0.7950.99
467_Y498_A0.7940.99
326_A515_T0.7930.99
557_G582_F0.7920.99
359_T512_H0.7920.99
191_Q197_P0.7880.99
273_V276_V0.7860.99
386_P489_G0.7860.99
397_G541_N0.7860.99
365_L513_A0.7850.99
186_V209_I0.7820.99
104_K158_Y0.7820.99
25_I29_K0.7810.99
214_N218_L0.7800.99
326_A512_H0.7800.99
133_Q153_E0.7800.99
578_H600_P0.7750.99
79_V187_G0.7690.98
27_S30_E0.7670.98
411_I450_R0.7660.98
215_N219_Y0.7660.98
147_F154_L0.7650.98
226_D229_K0.7640.98
618_G622_A0.7630.98
398_P460_A0.7630.98
386_P495_M0.7620.98
284_V287_S0.7610.98
392_P440_F0.7590.98
508_Y535_I0.7570.98
208_F211_A0.7560.98
399_Y405_A0.7550.98
198_L206_M0.7540.98
202_T206_M0.7540.98
478_L485_G0.7530.98
580_M611_P0.7530.98
118_N128_A0.7530.98
114_A118_N0.7520.98
357_H500_T0.7500.98
580_M608_S0.7490.98
31_V35_K0.7480.98
33_Q36_S0.7480.98
138_N176_T0.7450.98
240_K251_K0.7450.98
30_E34_M0.7450.98
208_F232_Q0.7450.98
93_L170_L0.7430.98
396_Y440_F0.7430.98
108_F158_Y0.7430.98
249_E253_A0.7410.98
470_A494_E0.7400.98
502_F536_F0.7390.98
92_F131_I0.7380.98
117_S120_K0.7370.98
551_V555_G0.7350.98
195_S261_D0.7320.98
563_N566_Y0.7320.98
30_E36_S0.7300.98
248_K251_K0.7280.98
540_T544_L0.7280.98
281_T285_S0.7260.98
349_Q373_K0.7250.98
144_E149_R0.7230.98
62_D329_P0.7230.98
141_L149_R0.7230.98
393_L495_M0.7220.98
398_P402_Q0.7220.98
63_G324_Y0.7220.98
496_T590_T0.7210.98
351_G378_R0.7200.98
287_S526_Y0.7170.98
579_D596_G0.7160.98
92_F177_I0.7140.97
106_F158_Y0.7110.97
387_G574_S0.7100.97
591_M616_W0.7090.97
424_Q430_T0.7090.97
54_Q78_L0.7090.97
24_V27_S0.7080.97
284_V517_V0.7080.97
356_N588_T0.7080.97
280_F284_V0.7050.97
376_F381_Q0.7040.97
503_G568_G0.7030.97
84_I186_V0.7020.97
408_S437_D0.7000.97
57_Y68_E0.6990.97
203_V239_L0.6990.97
386_P485_G0.6980.97
124_I128_A0.6970.97
330_Y334_Q0.6970.97
457_I477_Y0.6970.97
343_L369_K0.6920.97
514_I517_V0.6920.97
234_R238_G0.6890.97
32_K35_K0.6890.97
383_Y489_G0.6890.97
497_K510_P0.6870.97
83_K187_G0.6860.97
551_V582_F0.6860.97
284_V321_V0.6840.97
178_Y183_V0.6840.97
88_V201_L0.6820.97
234_R237_K0.6810.97
232_Q258_I0.6800.97
285_S313_V0.6800.97
546_K550_S0.6790.97
278_D283_L0.6780.97
277_N283_L0.6780.97
536_F540_T0.6770.97
214_N235_L0.6770.97
279_E362_I0.6760.97
195_S263_E0.6740.96
574_S578_H0.6730.96
333_N336_V0.6730.96
519_D522_G0.6710.96
203_V206_M0.6700.96
312_R316_L0.6690.96
278_D371_Y0.6670.96
459_K463_Y0.6650.96
274_S277_N0.6650.96
232_Q257_K0.6650.96
400_I407_T0.6640.96
348_V597_K0.6630.96
551_V569_G0.6630.96
328_D363_I0.6620.96
351_G492_P0.6620.96
84_I87_E0.6620.96
495_M581_W0.6600.96
276_V279_E0.6590.96
585_L590_T0.6590.96
355_I500_T0.6570.96
335_V354_V0.6570.96
383_Y494_E0.6570.96
565_P587_D0.6570.96
400_I405_A0.6560.96
560_A613_L0.6550.96
548_M568_G0.6540.96
118_N154_L0.6540.96
559_K614_S0.6540.96
278_D284_V0.6520.96
441_K551_V0.6490.96
549_S552_V0.6490.96
29_K36_S0.6480.96
91_I244_V0.6470.96
141_L156_Y0.6470.96
210_C213_P0.6450.95
434_V438_T0.6450.95
368_G378_R0.6440.95
510_P531_K0.6420.95
240_K243_G0.6410.95
398_P455_V0.6410.95
186_V198_L0.6410.95
257_K260_L0.6400.95
179_F213_P0.6400.95
256_Q259_K0.6400.95
560_A617_K0.6380.95
95_S210_C0.6380.95
338_Q615_I0.6380.95
275_Y279_E0.6370.95
585_L620_L0.6370.95
60_D63_G0.6360.95
331_M334_Q0.6360.95
106_F111_M0.6350.95
284_V323_I0.6330.95
413_A444_Y0.6330.95
95_S213_P0.6270.95
94_T239_L0.6260.95
67_S277_N0.6260.95
132_T157_S0.6260.95
36_S40_V0.6250.95
164_Y168_E0.6250.95
146_S149_R0.6240.95
273_V278_D0.6240.95
538_V542_M0.6230.95
376_F379_A0.6230.95
28_G31_V0.6230.95
208_F221_P0.6230.95
170_L174_L0.6220.94
19_L22_F0.6210.94
593_V616_W0.6210.94
28_G36_S0.6200.94
211_A234_R0.6190.94
330_Y333_N0.6190.94
229_K258_I0.6180.94
552_V560_A0.6180.94
314_S318_K0.6180.94
115_T119_V0.6180.94
196_K202_T0.6170.94
187_G199_K0.6170.94
36_S39_Q0.6160.94
606_L611_P0.6150.94
190_A206_M0.6150.94
365_L380_Y0.6140.94
273_V280_F0.6140.94
245_I253_A0.6140.94
495_M592_G0.6140.94
18_P25_I0.6140.94
211_A235_L0.6120.94
208_F258_I0.6120.94
69_I281_T0.6110.94
593_V612_Q0.6110.94
253_A256_Q0.6110.94
597_K601_T0.6110.94
125_D145_R0.6110.94
276_V283_L0.6090.94
431_Y438_T0.6080.94
118_N145_R0.6080.94
400_I436_L0.6080.94
388_S391_K0.6070.94
88_V198_L0.6060.94
273_V277_N0.6060.94
562_F567_I0.6060.94
81_F93_L0.6060.94
334_Q337_A0.6040.94
464_I469_F0.6030.94
190_A201_L0.6030.94
118_N122_K0.6010.93
206_M213_P0.6010.93
608_S612_Q0.6000.93
194_F208_F0.6000.93
110_G126_Q0.5990.93
214_N234_R0.5980.93
501_T535_I0.5960.93
501_T536_F0.5960.93
28_G32_K0.5950.93
95_S242_A0.5940.93
349_Q598_D0.5940.93
137_R145_R0.5930.93
154_L157_S0.5930.93
136_S156_Y0.5930.93
562_F621_Q0.5920.93
256_Q260_L0.5920.93
465_E472_L0.5920.93
35_K39_Q0.5910.93
19_L23_T0.5900.93
377_N381_Q0.5900.93
283_L514_I0.5890.93
464_I498_A0.5880.93
574_S579_D0.5870.93
467_Y535_I0.5870.93
544_L548_M0.5860.93
416_F453_D0.5860.93
180_N193_Y0.5860.93
383_Y491_T0.5850.93
562_F617_K0.5850.93
139_L172_A0.5840.92
465_E470_A0.5840.92
425_N430_T0.5840.92
214_N231_R0.5830.92
137_R149_R0.5830.92
75_N188_S0.5830.92
497_K500_T0.5820.92
357_H587_D0.5810.92
118_N123_K0.5790.92
409_S451_M0.5780.92
410_T435_T0.5780.92
365_L379_A0.5750.92
580_M609_I0.5740.92
479_L485_G0.5740.92
98_R241_D0.5730.92
34_M37_L0.5720.92
607_H610_S0.5720.92
470_A473_V0.5710.92
402_Q405_A0.5710.92
358_Q504_N0.5700.92
338_Q622_A0.5690.91
415_K424_Q0.5690.91
79_V85_P0.5690.91
394_L452_L0.5670.91
450_R454_R0.5650.91
490_M494_E0.5650.91
133_Q141_L0.5650.91
562_F565_P0.5640.91
280_F283_L0.5640.91
81_F85_P0.5630.91
82_N167_N0.5630.91
577_Y580_M0.5630.91
343_L350_G0.5620.91
311_A314_S0.5610.91
553_K558_K0.5600.91
22_F30_E0.5590.91
232_Q260_L0.5580.91
517_V526_Y0.5580.91
84_I171_E0.5570.91
275_Y368_G0.5570.91
141_L144_E0.5560.91
355_I497_K0.5560.91
55_N68_E0.5560.91
43_K46_D0.5560.91
126_Q145_R0.5550.90
391_K445_N0.5530.90
19_L32_K0.5530.90
133_Q137_R0.5520.90
190_A194_F0.5510.90
44_N47_L0.5510.90
349_Q368_G0.5490.90
16_I19_L0.5490.90
70_V75_N0.5490.90
384_R594_W0.5470.90
21_A25_I0.5450.90
273_V281_T0.5450.90
84_I92_F0.5430.89
99_H161_E0.5430.89
80_P84_I0.5430.89
493_L513_A0.5430.89
589_Y619_T0.5420.89
181_N222_L0.5420.89
613_L617_K0.5410.89
117_S124_I0.5410.89
115_T147_F0.5410.89
55_N75_N0.5400.89
386_P389_S0.5400.89
493_L496_T0.5400.89
448_A482_A0.5400.89
440_F548_M0.5400.89
21_A28_G0.5390.89
440_F544_L0.5370.89
280_F287_S0.5340.89
500_T509_T0.5340.89
545_K549_S0.5340.89
537_S541_N0.5340.89
189_A193_Y0.5330.89
437_D547_L0.5320.89
190_A196_K0.5320.89
503_G590_T0.5320.89
413_A446_T0.5310.88
464_I468_H0.5310.88
212_I215_N0.5310.88
584_G620_L0.5310.88
204_G208_F0.5300.88
505_S545_K0.5300.88
225_F260_L0.5300.88
275_Y283_L0.5290.88
236_L253_A0.5280.88
148_S151_L0.5280.88
396_Y547_L0.5270.88
190_A198_L0.5260.88
580_M595_V0.5260.88
211_A231_R0.5260.88
246_T250_L0.5250.88
284_V316_L0.5250.88
313_V317_M0.5250.88
104_K161_E0.5250.88
350_G595_V0.5240.88
392_P499_Y0.5240.88
552_V561_Y0.5240.88
85_P197_P0.5240.88
101_Y170_L0.5230.88
323_I514_I0.5230.88
28_G35_K0.5230.88
447_P450_R0.5220.88
111_M147_F0.5220.88
282_Q286_E0.5210.87
512_H515_T0.5200.87
44_N48_K0.5200.87
91_I94_T0.5200.87
277_N281_T0.5200.87
332_Q365_L0.5200.87
353_A590_T0.5190.87
502_F548_M0.5190.87
220_D223_K0.5190.87
398_P459_K0.5180.87
149_R153_E0.5180.87
208_F222_L0.5180.87
435_T441_K0.5180.87
500_T504_N0.5180.87
473_V494_E0.5180.87
155_A159_Q0.5170.87
402_Q455_V0.5170.87
277_N287_S0.5170.87
443_S570_K0.5160.87
316_L320_G0.5160.87
208_F225_F0.5150.87
315_T321_V0.5150.87
59_Y63_G0.5150.87
24_V31_V0.5150.87
426_Y577_Y0.5140.87
32_K37_L0.5140.87
229_K257_K0.5130.87
17_I30_E0.5130.87
389_S592_G0.5120.87
111_M115_T0.5120.87
321_V517_V0.5110.86
207_A236_L0.5110.86
66_V327_L0.5110.86
277_N280_F0.5110.86
25_I32_K0.5110.86
225_F228_T0.5100.86
582_F616_W0.5090.86
218_L224_H0.5090.86
586_T620_L0.5090.86
32_K39_Q0.5080.86
207_A253_A0.5080.86
215_N227_Y0.5080.86
23_T30_E0.5070.86
463_Y540_T0.5070.86
109_M112_V0.5060.86
95_S211_A0.5060.86
219_Y227_Y0.5060.86
469_F495_M0.5050.86
24_V32_K0.5050.86
327_L513_A0.5030.86
544_L547_L0.5030.86
187_G190_A0.5030.86
283_L512_H0.5020.86
515_T527_K0.5020.86
183_V188_S0.5010.85
465_E469_F0.5000.85
413_A447_P0.5000.85
125_D128_A0.5000.85
337_A340_N0.5000.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4oonA 1 0.5417 100 0.124 Contact Map
2jchA 1 0.5737 100 0.151 Contact Map
3udfA 2 0.7548 100 0.156 Contact Map
3vmaA 1 0.9135 100 0.163 Contact Map
2olvA 1 0.875 100 0.2 Contact Map
3zg9B 1 0.6955 100 0.371 Contact Map
2y2mA 2 0.5849 100 0.555 Contact Map
3un7A 1 0.6026 100 0.599 Contact Map
2v2fF 1 0.5224 100 0.611 Contact Map
2oqoA 2 0.2901 100 0.616 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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