GREMLIN Database
YLXH - Flagellum site-determining protein YlxH
UniProt: P40742 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 298 (235)
Sequences: 15465 (9796)
Seq/√Len: 639.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
109_R142_F4.1641.00
236_S263_S3.8821.00
49_T146_L3.5931.00
59_K269_D3.1611.00
56_L144_Y2.8711.00
48_I264_V2.8501.00
250_P253_I2.8051.00
61_K144_Y2.7961.00
35_A164_A2.7921.00
32_K166_D2.5431.00
64_L142_F2.4931.00
203_R237_D2.4431.00
172_T203_R2.3801.00
65_L75_I2.2141.00
50_L75_I2.1211.00
103_V109_R2.0981.00
49_T65_L2.0931.00
36_V52_M2.0511.00
78_L176_T2.0301.00
58_D265_R2.0231.00
55_A268_A2.0141.00
48_I200_A1.9951.00
53_A65_L1.9851.00
218_S222_H1.9561.00
55_A252_F1.9371.00
240_I243_K1.9341.00
200_A267_L1.8931.00
62_K143_D1.8801.00
59_K265_R1.8381.00
128_W131_F1.7631.00
205_R237_D1.7551.00
57_Q108_L1.6981.00
77_I179_M1.6541.00
233_G270_A1.6511.00
128_W132_A1.6481.00
56_L146_L1.6441.00
98_L141_Q1.6261.00
53_A146_L1.5831.00
61_K272_F1.5811.00
33_T147_F1.5651.00
166_D197_M1.5561.00
238_D260_A1.5381.00
124_D128_W1.5231.00
68_L160_F1.5181.00
50_L78_L1.5001.00
129_T132_A1.4961.00
36_V168_L1.4951.00
233_G267_L1.4891.00
57_Q107_G1.4711.00
52_M271_L1.4671.00
68_L147_F1.4301.00
35_A149_M1.4271.00
214_F217_L1.4151.00
96_P99_Q1.4101.00
222_H225_L1.3831.00
79_I108_L1.3721.00
166_D198_K1.3721.00
52_M268_A1.3661.00
36_V49_T1.3531.00
219_R222_H1.3441.00
232_A270_A1.3421.00
61_K143_D1.3321.00
124_D127_K1.3201.00
204_C234_S1.2971.00
32_K165_E1.2961.00
86_T89_D1.2911.00
235_V260_A1.2891.00
241_V260_A1.2881.00
167_I188_L1.2871.00
68_L87_I1.2831.00
168_L200_A1.2791.00
119_V122_Q1.2791.00
37_I184_A1.2751.00
95_K99_Q1.2691.00
44_G202_N1.2671.00
258_A261_S1.2641.00
53_A75_I1.2491.00
262_R265_R1.2461.00
173_P201_V1.2451.00
50_L79_I1.2371.00
48_I202_N1.2241.00
73_G76_D1.2221.00
74_N180_D1.2171.00
240_I255_S1.2151.00
130_F134_E1.2111.00
129_T133_N1.1961.00
249_V254_K1.1941.00
222_H234_S1.1931.00
81_N110_Y1.1821.00
119_V123_L1.1781.00
201_V218_S1.1741.00
239_V243_K1.1741.00
219_R223_M1.1581.00
59_K272_F1.1441.00
238_D258_A1.1341.00
115_T183_S1.1261.00
120_M123_L1.1171.00
53_A108_L1.1121.00
220_T223_M1.1101.00
55_A265_R1.1011.00
231_F234_S1.0901.00
64_L101_L1.0891.00
48_I52_M1.0861.00
56_L63_V1.0801.00
46_S75_I1.0801.00
174_E177_A1.0781.00
85_A89_D1.0761.00
202_N264_V1.0661.00
97_L111_I1.0621.00
46_S78_L1.0551.00
110_Y115_T1.0501.00
56_L268_A1.0491.00
126_R130_F1.0431.00
213_A217_L1.0421.00
37_I149_M1.0381.00
34_L144_Y1.0331.00
31_A139_L1.0321.00
64_L145_V1.0171.00
269_D273_E1.0091.00
36_V48_I1.0071.00
99_Q102_S1.0021.00
243_K247_E0.9991.00
263_S266_I0.9981.00
206_D215_A0.9951.00
109_R140_S0.9951.00
176_T245_V0.9931.00
174_E242_S0.9911.00
126_R129_T0.9891.00
144_Y272_F0.9891.00
266_I269_D0.9871.00
266_I270_A0.9861.00
149_M160_F0.9861.00
265_R269_D0.9841.00
259_K262_R0.9791.00
256_P261_S0.9771.00
166_D195_L0.9711.00
249_V253_I0.9671.00
218_S225_L0.9661.00
101_L109_R0.9641.00
51_N54_L0.9621.00
47_N241_V0.9561.00
74_N176_T0.9511.00
55_A59_K0.9411.00
235_V263_S0.9401.00
85_A95_K0.9361.00
79_I110_Y0.9341.00
221_I225_L0.9331.00
90_V100_S0.9231.00
73_G113_G0.9231.00
54_L58_D0.9121.00
51_N252_F0.9111.00
98_L102_S0.9091.00
34_L271_L0.8851.00
201_V204_C0.8851.00
62_K141_Q0.8801.00
127_K130_F0.8801.00
70_I156_D0.8741.00
267_L271_L0.8691.00
219_R225_L0.8591.00
170_I202_N0.8591.00
100_S111_I0.8591.00
33_T145_V0.8581.00
206_D209_E0.8511.00
186_K189_V0.8491.00
220_T225_L0.8491.00
36_V146_L0.8481.00
34_L166_D0.8451.00
66_I147_F0.8411.00
252_F265_R0.8411.00
189_V193_N0.8361.00
131_F134_E0.8321.00
125_Q128_W0.8281.00
58_D252_F0.8251.00
33_T139_L0.8241.00
260_A263_S0.8141.00
66_I145_V0.8121.00
37_I157_Q0.8081.00
95_K98_L0.8081.00
93_D96_P0.8071.00
247_E254_K0.8071.00
51_N250_P0.8061.00
251_F261_S0.8041.00
214_F218_S0.8041.00
88_I92_T0.7961.00
95_K100_S0.7891.00
58_D253_I0.7881.00
169_I185_V0.7851.00
40_K45_K0.7851.00
213_A216_R0.7841.00
104_G110_Y0.7831.00
208_K214_F0.7821.00
51_N264_V0.7801.00
160_F164_A0.7791.00
39_G187_H0.7761.00
127_K131_F0.7731.00
47_N245_V0.7731.00
169_I181_A0.7721.00
131_F135_L0.7701.00
43_V177_A0.7691.00
31_A145_V0.7691.00
173_P204_C0.7661.00
198_K231_F0.7651.00
218_S234_S0.7641.00
238_D259_K0.7631.00
132_A135_L0.7591.00
54_L252_F0.7581.00
168_L271_L0.7571.00
33_T165_E0.7531.00
220_T224_F0.7531.00
55_A264_V0.7511.00
99_Q103_V0.7501.00
128_W134_E0.7491.00
76_D114_G0.7451.00
172_T177_A0.7411.00
54_L108_L0.7351.00
87_I111_I0.7341.00
87_I90_V0.7331.00
45_K151_A0.7331.00
62_K109_R0.7291.00
255_S258_A0.7271.00
149_M157_Q0.7221.00
109_R112_S0.7211.00
48_I170_I0.7141.00
217_L221_I0.7111.00
105_P253_I0.7091.00
63_V143_D0.7051.00
77_I175_P0.7021.00
32_K144_Y0.6991.00
129_T135_L0.6931.00
221_I224_F0.6931.00
125_Q129_T0.6901.00
63_V108_L0.6901.00
71_G154_S0.6891.00
68_L156_D0.6891.00
158_L187_H0.6871.00
259_K263_S0.6871.00
124_D132_A0.6861.00
262_R266_I0.6861.00
142_F145_V0.6821.00
154_S157_Q0.6781.00
236_S259_K0.6781.00
139_L165_E0.6761.00
123_L126_R0.6731.00
54_L253_I0.6711.00
101_L142_F0.6701.00
98_L101_L0.6691.00
55_A261_S0.6691.00
216_R219_R0.6681.00
128_W135_L0.6661.00
270_A274_R0.6611.00
86_T114_G0.6611.00
75_I110_Y0.6591.00
31_A141_Q0.6591.00
74_N179_M0.6551.00
76_D112_S0.6551.00
218_S221_I0.6531.00
65_L79_I0.6521.00
73_G114_G0.6461.00
244_A251_F0.6451.00
218_S224_F0.6431.00
252_F261_S0.6421.00
38_S43_V0.6401.00
55_A58_D0.6391.00
60_G107_G0.6341.00
35_A160_F0.6341.00
261_S265_R0.6311.00
244_A254_K0.6301.00
52_M267_L0.6251.00
205_R214_F0.6251.00
209_E215_A0.6221.00
146_L271_L0.6221.00
40_K43_V0.6221.00
49_T75_I0.6211.00
257_Q262_R0.6171.00
182_Y186_K0.6141.00
208_K239_V0.6131.00
85_A100_S0.6111.00
215_A219_R0.6101.00
68_L128_W0.6091.00
85_A99_Q0.6051.00
201_V221_I0.6021.00
198_K232_A0.6011.00
205_R239_V0.5981.00
54_L250_P0.5961.00
243_K254_K0.5941.00
48_I235_V0.5941.00
183_S186_K0.5901.00
90_V111_I0.5881.00
223_M226_D0.5851.00
35_A167_I0.5851.00
270_A273_E0.5801.00
97_L101_L0.5791.00
241_V245_V0.5741.00
166_D196_S0.5741.00
33_T164_A0.5721.00
175_P179_M0.5711.00
71_G151_A0.5711.00
109_R141_Q0.5701.00
94_R98_L0.5681.00
201_V234_S0.5681.00
199_V225_L0.5661.00
235_V267_L0.5621.00
40_K176_T0.5601.00
39_G184_A0.5601.00
239_V242_S0.5601.00
63_V146_L0.5591.00
231_F270_A0.5581.00
161_I192_E0.5581.00
63_V144_Y0.5571.00
244_A250_P0.5531.00
101_L111_I0.5531.00
222_H232_A0.5531.00
256_P262_R0.5521.00
139_L145_V0.5501.00
175_P246_V0.5501.00
32_K197_M0.5471.00
124_D156_D0.5451.00
147_F160_F0.5431.00
65_L110_Y0.5370.99
104_G107_G0.5360.99
120_M124_D0.5360.99
50_L65_L0.5360.99
111_I115_T0.5320.99
74_N77_I0.5310.99
89_D94_R0.5300.99
121_F155_K0.5280.99
77_I176_T0.5280.99
155_K158_L0.5260.99
31_A62_K0.5250.99
122_Q128_W0.5240.99
122_Q125_Q0.5220.99
123_L127_K0.5190.99
129_T163_S0.5180.99
62_K142_F0.5170.99
97_L100_S0.5150.99
38_S45_K0.5150.99
153_L187_H0.5150.99
240_I258_A0.5130.99
244_A249_V0.5130.99
251_F260_A0.5090.99
188_L194_K0.5080.99
251_F254_K0.5080.99
37_I161_I0.5070.99
216_R220_T0.5070.99
56_L272_F0.5060.99
182_Y226_D0.5060.99
59_K268_A0.5050.99
51_N251_F0.5040.99
35_A147_F0.5040.99
32_K61_K0.5030.99
155_K159_P0.5030.99
197_M231_F0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rz3A 2 0.8154 100 0.302 Contact Map
1hyqA 1 0.7752 100 0.348 Contact Map
4pfsA 1 0.7785 100 0.363 Contact Map
1g3qA 1 0.7886 100 0.376 Contact Map
3ea0A 2 0.7819 100 0.385 Contact Map
1wcv1 2 0.7953 100 0.386 Contact Map
3pg5A 2 0.7248 100 0.387 Contact Map
3fwyA 2 0.8389 100 0.395 Contact Map
3q9lA 2 0.8188 100 0.402 Contact Map
2ynmA 2 0.8356 100 0.406 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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