BGLH - BACSU - GREMLIN Contacts

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BGLH - Aryl-phospho-beta-D-glucosidase BglH

UniProt:	P40740	Sequences: MSSNEKRFPEGFLWGGAVAANQVEGAYNEGGKGLSTADVSPNGIMSPFDESMTSLNLYHNGIDFYHRYKEDIALFAEMGFKAFRTSIAWTRIFPNGDEEEPNEEGLRFYDDLFDELLKHHIEPVVTISHYEMPLGLVKNYGGWKNRKVIEFYERYAKTVFKRYQHKVKYWMTFNEINVVLHAPFTGGGLVFEEGENKLNAMYQAAHHQFVASALAVKAGHDIIPDSKIGCMIAATTTYPMTSKPEDVFAAMENERKTLFFSDVQARGAYPGYMKRYLAENNIEIEMAEGDEELLKEHTVDYIGFSYYMSMAASTDPEELAKSGGNLLGGVKNPYLKSSEWGWQIDPKGLRITLNTLYDRYQKPLFIVENGLGAVDKVEEDGTIQDDYRINYLRDHLIEAREAIADGVELIGYTSWGPIDLVSASTAEMKKRYGFIYVDRDNEGNGTFNRIKKKSFNWYQQVIATNGESL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	469 (440)
Sequences:	6788 (4229)
Seq/√Len:	201.6

ECOLI - ASCB BGLB BGLA
BACSU - BGLH BGLC BGLA GMUD
SULSO - BGAL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
30_G	104_E	4.330	1.00
384_Q	453_K	4.102	1.00
114_D	166_K	3.603	1.00
110_D	166_K	3.199	1.00
399_A	409_L	3.182	1.00
76_A	119_H	3.128	1.00
69_K	115_E	3.060	1.00
110_D	162_R	2.948	1.00
127_I	159_V	2.923	1.00
451_K	455_F	2.891	1.00
115_E	118_K	2.867	1.00
103_E	107_R	2.865	1.00
107_R	111_D	2.783	1.00
63_D	66_H	2.776	1.00
103_E	162_R	2.753	1.00
306_Y	395_H	2.706	1.00
93_F	158_T	2.696	1.00
398_E	401_E	2.686	1.00
241_T	246_D	2.630	1.00
157_K	161_K	2.615	1.00
29_E	66_H	2.573	1.00
16_G	80_F	2.455	1.00
392_L	414_S	2.378	1.00
73_A	119_H	2.322	1.00
350_R	405_D	2.321	1.00
354_N	405_D	2.296	1.00
146_R	290_D	2.269	1.00
150_E	214_L	2.255	1.00
390_N	394_D	2.242	1.00
219_G	228_I	2.231	1.00
42_N	59_H	2.210	1.00
217_K	221_D	2.204	1.00
113_F	163_Y	2.184	1.00
436_Y	450_I	2.157	1.00
64_F	108_F	2.153	1.00
386_D	453_K	2.145	1.00
69_K	111_D	2.123	1.00
82_A	413_T	2.112	1.00
72_I	112_L	2.058	1.00
122_E	168_K	2.050	1.00
64_F	83_F	2.036	1.00
459_Q	463_A	2.013	1.00
87_I	125_V	1.998	1.00
378_E	382_T	1.950	1.00
117_L	166_K	1.943	1.00
39_V	134_L	1.920	1.00
153_E	218_A	1.907	1.00
104_E	107_R	1.879	1.00
271_G	275_R	1.878	1.00
72_I	119_H	1.875	1.00
157_K	218_A	1.874	1.00
85_T	113_F	1.874	1.00
289_G	292_E	1.856	1.00
206_H	269_Y	1.836	1.00
27_Y	34_L	1.827	1.00
35_S	90_T	1.806	1.00
219_G	226_S	1.798	1.00
350_R	401_E	1.794	1.00
26_A	29_E	1.789	1.00
157_K	222_I	1.787	1.00
34_L	39_V	1.787	1.00
110_D	114_D	1.777	1.00
214_L	293_L	1.776	1.00
238_Y	351_I	1.759	1.00
14_W	465_N	1.717	1.00
115_E	119_H	1.706	1.00
223_I	226_S	1.703	1.00
18_V	23_V	1.694	1.00
114_D	117_L	1.686	1.00
122_E	169_Y	1.673	1.00
286_M	291_E	1.668	1.00
347_K	398_E	1.649	1.00
73_A	115_E	1.641	1.00
85_T	112_L	1.632	1.00
116_L	121_I	1.626	1.00
113_F	117_L	1.620	1.00
353_L	407_V	1.605	1.00
460_Q	463_A	1.596	1.00
140_Y	151_F	1.596	1.00
110_D	163_Y	1.594	1.00
135_G	139_N	1.588	1.00
350_R	354_N	1.584	1.00
268_A	295_K	1.584	1.00
306_Y	348_G	1.581	1.00
355_T	359_R	1.572	1.00
153_E	214_L	1.562	1.00
266_R	361_Q	1.559	1.00
72_I	115_E	1.550	1.00
365_F	410_I	1.547	1.00
171_M	231_M	1.541	1.00
13_L	82_A	1.541	1.00
68_Y	111_D	1.536	1.00
21_N	58_Y	1.527	1.00
148_V	151_F	1.522	1.00
160_F	219_G	1.495	1.00
205_A	260_F	1.493	1.00
82_A	124_V	1.457	1.00
165_H	223_I	1.450	1.00
438_D	446_T	1.448	1.00
259_F	273_M	1.446	1.00
18_V	83_F	1.446	1.00
67_R	70_E	1.442	1.00
72_I	116_L	1.434	1.00
33_G	96_G	1.428	1.00
144_K	200_A	1.427	1.00
369_N	412_Y	1.424	1.00
75_F	80_F	1.418	1.00
349_L	399_A	1.413	1.00
171_M	301_Y	1.411	1.00
93_F	101_P	1.406	1.00
261_S	302_I	1.403	1.00
106_L	158_T	1.403	1.00
357_Y	362_K	1.401	1.00
95_N	98_E	1.398	1.00
141_G	145_N	1.380	1.00
218_A	221_D	1.371	1.00
77_E	455_F	1.370	1.00
414_S	434_F	1.368	1.00
39_V	139_N	1.363	1.00
85_T	125_V	1.362	1.00
254_E	272_Y	1.361	1.00
43_G	51_S	1.361	1.00
124_V	413_T	1.346	1.00
339_E	374_V	1.341	1.00
63_D	67_R	1.333	1.00
26_A	66_H	1.322	1.00
460_Q	464_T	1.313	1.00
168_K	225_D	1.311	1.00
87_I	159_V	1.310	1.00
230_C	264_Q	1.309	1.00
268_A	274_K	1.308	1.00
457_W	461_V	1.306	1.00
451_K	456_N	1.290	1.00
353_L	399_A	1.289	1.00
169_Y	227_K	1.282	1.00
396_L	399_A	1.278	1.00
268_A	361_Q	1.255	1.00
134_L	138_K	1.253	1.00
173_F	211_A	1.247	1.00
97_D	151_F	1.240	1.00
456_N	459_Q	1.231	1.00
287_A	290_D	1.229	1.00
197_K	200_A	1.225	1.00
150_E	153_E	1.224	1.00
377_V	450_I	1.220	1.00
87_I	92_I	1.219	1.00
146_R	207_H	1.219	1.00
291_E	294_L	1.218	1.00
173_F	208_Q	1.214	1.00
394_D	397_I	1.212	1.00
393_R	397_I	1.211	1.00
73_A	77_E	1.211	1.00
147_K	150_E	1.210	1.00
179_V	208_Q	1.206	1.00
75_F	435_I	1.190	1.00
354_N	407_V	1.187	1.00
106_L	162_R	1.180	1.00
382_T	453_K	1.177	1.00
64_F	112_L	1.169	1.00
143_W	148_V	1.163	1.00
68_Y	115_E	1.161	1.00
195_E	200_A	1.159	1.00
127_I	152_Y	1.158	1.00
62_I	418_I	1.158	1.00
110_D	165_H	1.155	1.00
132_M	148_V	1.152	1.00
357_Y	408_E	1.149	1.00
262_D	359_R	1.147	1.00
160_F	215_A	1.142	1.00
134_L	139_N	1.139	1.00
26_A	30_G	1.134	1.00
400_R	404_A	1.130	1.00
239_P	247_V	1.129	1.00
27_Y	32_K	1.124	1.00
97_D	140_Y	1.123	1.00
156_A	215_A	1.122	1.00
18_V	85_T	1.122	1.00
33_G	135_G	1.120	1.00
239_P	250_A	1.120	1.00
458_Y	462_I	1.113	1.00
9_P	403_I	1.110	1.00
262_D	266_R	1.109	1.00
161_K	222_I	1.109	1.00
439_R	447_F	1.100	1.00
153_E	215_A	1.100	1.00
160_F	228_I	1.093	1.00
244_P	247_V	1.090	1.00
219_G	223_I	1.090	1.00
378_E	384_Q	1.089	1.00
400_R	403_I	1.087	1.00
147_K	151_F	1.081	1.00
244_P	248_F	1.077	1.00
237_T	253_N	1.076	1.00
106_L	110_D	1.072	1.00
347_K	351_I	1.069	1.00
77_E	451_K	1.069	1.00
113_F	125_V	1.068	1.00
113_F	166_K	1.068	1.00
95_N	135_G	1.067	1.00
240_M	313_S	1.059	1.00
216_V	220_H	1.059	1.00
234_A	352_T	1.057	1.00
110_D	117_L	1.057	1.00
8_F	403_I	1.055	1.00
153_E	157_K	1.053	1.00
219_G	224_P	1.047	1.00
214_L	218_A	1.047	1.00
401_E	404_A	1.045	1.00
245_E	347_K	1.036	1.00
140_Y	147_K	1.035	1.00
8_F	400_R	1.034	1.00
349_L	409_L	1.032	1.00
33_G	94_P	1.031	1.00
254_E	258_L	1.030	1.00
248_F	252_E	1.029	1.00
390_N	393_R	1.028	1.00
254_E	273_M	1.028	1.00
218_A	222_I	1.028	1.00
101_P	158_T	1.027	1.00
156_A	218_A	1.024	1.00
381_G	450_I	1.023	1.00
340_W	372_G	1.020	1.00
67_R	448_N	1.019	1.00
207_H	210_V	1.019	1.00
288_E	291_E	1.019	1.00
245_E	314_T	1.017	1.00
60_N	439_R	1.016	1.00
337_S	343_Q	1.010	1.00
246_D	314_T	1.007	1.00
377_V	381_G	1.006	1.00
349_L	366_I	1.005	1.00
16_G	75_F	1.004	1.00
92_I	158_T	1.002	1.00
338_S	371_L	1.001	1.00
60_N	447_F	0.998	1.00
217_K	297_H	0.992	1.00
268_A	271_G	0.990	1.00
438_D	448_N	0.989	1.00
164_Q	226_S	0.979	1.00
243_K	247_V	0.979	1.00
247_V	250_A	0.978	1.00
275_R	278_A	0.978	1.00
389_I	457_W	0.978	1.00
32_K	90_T	0.977	1.00
159_V	163_Y	0.977	1.00
151_F	154_R	0.974	1.00
158_T	162_R	0.972	1.00
331_K	335_L	0.971	1.00
336_K	387_Y	0.970	0.99
23_V	64_F	0.970	0.99
124_V	169_Y	0.969	0.99
124_V	365_F	0.969	0.99
146_R	287_A	0.967	0.99
11_G	410_I	0.967	0.99
251_M	254_E	0.960	0.99
253_N	312_A	0.958	0.99
132_M	142_G	0.954	0.99
81_K	465_N	0.952	0.99
336_K	394_D	0.947	0.99
13_L	124_V	0.944	0.99
157_K	223_I	0.944	0.99
248_F	251_M	0.939	0.99
149_I	214_L	0.939	0.99
160_F	226_S	0.937	0.99
374_V	429_K	0.933	0.99
56_N	429_K	0.929	0.99
373_A	387_Y	0.926	0.99
216_V	228_I	0.925	0.99
141_G	144_K	0.924	0.99
431_R	439_R	0.916	0.99
180_L	204_A	0.915	0.99
93_F	98_E	0.914	0.99
98_E	135_G	0.909	0.99
107_R	110_D	0.907	0.99
265_A	362_K	0.905	0.99
70_E	73_A	0.903	0.99
229_G	303_G	0.903	0.99
357_Y	361_Q	0.901	0.99
198_L	280_N	0.901	0.99
156_A	160_F	0.898	0.99
193_E	196_N	0.886	0.99
162_R	166_K	0.886	0.99
237_T	250_A	0.886	0.99
340_W	430_K	0.884	0.99
377_V	382_T	0.884	0.99
215_A	218_A	0.884	0.99
73_A	76_A	0.882	0.99
111_D	114_D	0.881	0.99
242_S	247_V	0.878	0.99
418_I	437_V	0.877	0.99
106_L	159_V	0.877	0.99
331_K	337_S	0.876	0.99
80_F	417_P	0.873	0.99
461_V	465_N	0.870	0.99
165_H	226_S	0.869	0.99
276_Y	280_N	0.867	0.99
336_K	390_N	0.867	0.99
217_K	293_L	0.866	0.99
108_F	112_L	0.865	0.99
75_F	121_I	0.865	0.99
117_L	123_P	0.864	0.99
262_D	360_Y	0.864	0.99
371_L	387_Y	0.862	0.99
229_G	301_Y	0.860	0.99
110_D	113_F	0.859	0.99
372_G	430_K	0.856	0.99
251_M	272_Y	0.854	0.99
155_Y	159_V	0.849	0.99
403_I	409_L	0.846	0.99
52_M	55_L	0.846	0.99
232_I	261_S	0.846	0.99
212_S	216_V	0.845	0.99
31_G	102_N	0.845	0.99
289_G	293_L	0.843	0.99
128_S	132_M	0.843	0.99
227_K	363_P	0.842	0.99
164_Q	223_I	0.841	0.99
140_Y	148_V	0.840	0.99
349_L	398_E	0.838	0.99
97_D	139_N	0.834	0.98
95_N	100_E	0.834	0.98
347_K	401_E	0.830	0.98
172_T	230_C	0.827	0.98
171_M	303_G	0.826	0.98
309_S	343_Q	0.825	0.98
345_D	348_G	0.825	0.98
456_N	460_Q	0.824	0.98
149_I	210_V	0.823	0.98
275_R	279_E	0.823	0.98
173_F	179_V	0.823	0.98
214_L	217_K	0.822	0.98
14_W	396_L	0.821	0.98
304_F	364_L	0.819	0.98
128_S	131_E	0.818	0.98
354_N	358_D	0.816	0.98
7_R	10_E	0.815	0.98
144_K	195_E	0.814	0.98
7_R	400_R	0.812	0.98
383_I	450_I	0.809	0.98
240_M	246_D	0.808	0.98
386_D	390_N	0.807	0.98
397_I	401_E	0.799	0.98
309_S	348_G	0.799	0.98
96_G	135_G	0.798	0.98
258_L	359_R	0.797	0.98
77_E	459_Q	0.796	0.98
92_I	159_V	0.795	0.98
80_F	458_Y	0.794	0.98
172_T	212_S	0.791	0.98
350_R	398_E	0.789	0.98
178_V	233_A	0.788	0.98
308_M	343_Q	0.787	0.98
23_V	62_I	0.786	0.98
453_K	456_N	0.786	0.98
20_A	88_A	0.785	0.98
199_N	203_Q	0.785	0.98
309_S	345_D	0.785	0.98
36_T	132_M	0.785	0.98
234_A	304_F	0.782	0.98
97_D	135_G	0.778	0.98
68_Y	72_I	0.777	0.98
357_Y	407_V	0.776	0.98
101_P	106_L	0.775	0.98
158_T	161_K	0.770	0.97
138_K	184_F	0.766	0.97
88_A	131_E	0.763	0.97
243_K	246_D	0.763	0.97
353_L	409_L	0.762	0.97
192_E	195_E	0.759	0.97
32_K	35_S	0.756	0.97
271_G	274_K	0.754	0.97
251_M	355_T	0.751	0.97
344_I	373_A	0.750	0.97
145_N	151_F	0.749	0.97
60_N	63_D	0.747	0.97
103_E	110_D	0.746	0.97
375_D	378_E	0.745	0.97
13_L	122_E	0.745	0.97
237_T	312_A	0.744	0.97
76_A	120_H	0.744	0.97
354_N	357_Y	0.741	0.97
362_K	408_E	0.737	0.97
28_N	34_L	0.736	0.97
152_Y	156_A	0.733	0.97
332_N	335_L	0.733	0.97
265_A	299_V	0.733	0.97
105_G	108_F	0.732	0.97
182_A	188_G	0.731	0.97
265_A	302_I	0.730	0.96
435_I	451_K	0.730	0.96
9_P	408_E	0.729	0.96
58_Y	61_G	0.728	0.96
78_M	451_K	0.727	0.96
27_Y	59_H	0.725	0.96
172_T	228_I	0.723	0.96
97_D	154_R	0.720	0.96
164_Q	222_I	0.719	0.96
420_L	432_Y	0.718	0.96
117_L	168_K	0.717	0.96
123_P	168_K	0.717	0.96
209_F	264_Q	0.717	0.96
177_N	233_A	0.716	0.96
150_E	154_R	0.716	0.96
248_F	347_K	0.716	0.96
236_T	351_I	0.715	0.96
364_L	407_V	0.714	0.96
376_K	379_E	0.710	0.96
11_G	465_N	0.710	0.96
247_V	251_M	0.709	0.96
205_A	259_F	0.708	0.96
207_H	287_A	0.708	0.96
125_V	167_V	0.706	0.96
144_K	204_A	0.703	0.96
14_W	81_K	0.701	0.96
268_A	291_E	0.700	0.96
402_A	407_V	0.700	0.96
160_F	222_I	0.698	0.95
71_D	449_R	0.698	0.95
67_R	447_F	0.695	0.95
273_M	277_L	0.693	0.95
178_V	182_A	0.693	0.95
231_M	305_S	0.691	0.95
52_M	56_N	0.691	0.95
18_V	418_I	0.690	0.95
192_E	196_N	0.690	0.95
116_L	120_H	0.687	0.95
209_F	294_L	0.685	0.95
378_E	381_G	0.684	0.95
34_L	42_N	0.682	0.95
30_G	65_Y	0.680	0.95
396_L	461_V	0.677	0.95
117_L	122_E	0.677	0.95
26_A	65_Y	0.676	0.95
146_R	289_G	0.676	0.95
396_L	414_S	0.675	0.95
206_H	286_M	0.675	0.95
377_V	380_D	0.675	0.95
389_I	453_K	0.674	0.95
377_V	383_I	0.674	0.95
347_K	350_R	0.673	0.94
434_F	458_Y	0.668	0.94
116_L	119_H	0.668	0.94
23_V	420_L	0.664	0.94
363_P	408_E	0.663	0.94
291_E	295_K	0.663	0.94
211_A	215_A	0.662	0.94
124_V	171_M	0.662	0.94
159_V	170_W	0.662	0.94
213_A	294_L	0.662	0.94
238_Y	309_S	0.662	0.94
161_K	218_A	0.661	0.94
339_E	373_A	0.661	0.94
243_K	314_T	0.659	0.94
58_Y	426_A	0.658	0.94
157_K	221_D	0.658	0.94
95_N	139_N	0.657	0.94
78_M	434_F	0.656	0.94
267_G	295_K	0.654	0.94
72_I	121_I	0.654	0.94
27_Y	88_A	0.653	0.94
304_F	356_L	0.653	0.94
422_S	432_Y	0.652	0.94
85_T	116_L	0.651	0.93
401_E	405_D	0.649	0.93
288_E	292_E	0.647	0.93
382_T	450_I	0.647	0.93
306_Y	349_L	0.646	0.93
156_A	159_V	0.645	0.93
353_L	402_A	0.643	0.93
275_R	401_E	0.642	0.93
232_I	260_F	0.641	0.93
305_S	367_V	0.641	0.93
146_R	210_V	0.641	0.93
302_I	362_K	0.641	0.93
461_V	464_T	0.640	0.93
84_R	174_N	0.638	0.93
81_K	122_E	0.637	0.93
196_N	199_N	0.637	0.93
199_N	283_E	0.636	0.93
149_I	211_A	0.636	0.93
436_Y	452_K	0.634	0.93
13_L	81_K	0.634	0.93
75_F	417_P	0.634	0.93
447_F	451_K	0.633	0.92
17_A	413_T	0.632	0.92
93_F	97_D	0.631	0.92
258_L	355_T	0.630	0.92
113_F	167_V	0.628	0.92
152_Y	173_F	0.627	0.92
8_F	465_N	0.626	0.92
216_V	299_V	0.623	0.92
93_F	100_E	0.621	0.92
69_K	73_A	0.620	0.92
382_T	456_N	0.619	0.92
234_A	257_T	0.619	0.92
202_Y	277_L	0.617	0.92
421_V	439_R	0.616	0.91
234_A	261_S	0.616	0.91
167_V	170_W	0.615	0.91
34_L	134_L	0.615	0.91
315_D	318_E	0.614	0.91
128_S	179_V	0.613	0.91
213_A	298_T	0.613	0.91
386_D	389_I	0.612	0.91
259_F	277_L	0.612	0.91
93_F	154_R	0.612	0.91
399_A	403_I	0.612	0.91
278_A	281_N	0.611	0.91
136_L	151_F	0.611	0.91
313_S	328_G	0.611	0.91
254_E	355_T	0.610	0.91
340_W	425_T	0.610	0.91
36_T	138_K	0.609	0.91
144_K	203_Q	0.608	0.91
106_L	163_Y	0.608	0.91
436_Y	448_N	0.606	0.91
249_A	253_N	0.606	0.91
339_E	430_K	0.606	0.91
293_L	297_H	0.605	0.91
96_G	136_L	0.603	0.91
273_M	276_Y	0.602	0.91
287_A	291_E	0.602	0.91
227_K	410_I	0.601	0.90
15_G	413_T	0.600	0.90
241_T	313_S	0.600	0.90
61_G	447_F	0.598	0.90
234_A	356_L	0.597	0.90
117_L	120_H	0.597	0.90
154_R	158_T	0.597	0.90
127_I	160_F	0.594	0.90
365_F	411_G	0.594	0.90
87_I	113_F	0.593	0.90
11_G	403_I	0.593	0.90
81_K	462_I	0.592	0.90
69_K	72_I	0.592	0.90
203_Q	207_H	0.591	0.90
240_M	311_A	0.590	0.90
364_L	409_L	0.588	0.89
169_Y	365_F	0.587	0.89
41_P	421_V	0.584	0.89
420_L	423_A	0.582	0.89
222_I	226_S	0.582	0.89
111_D	115_E	0.581	0.89
331_K	334_Y	0.579	0.89
34_L	90_T	0.578	0.89
18_V	417_P	0.577	0.89
92_I	106_L	0.577	0.89
76_A	118_K	0.577	0.89
53_T	425_T	0.576	0.89
417_P	435_I	0.576	0.89
74_L	435_I	0.576	0.89
79_G	459_Q	0.575	0.88
8_F	14_W	0.575	0.88
324_G	327_L	0.574	0.88
149_I	153_E	0.574	0.88
213_A	297_H	0.573	0.88
258_L	262_D	0.572	0.88
217_K	298_T	0.570	0.88
381_G	448_N	0.570	0.88
114_D	165_H	0.570	0.88
78_M	455_F	0.568	0.88
239_P	246_D	0.568	0.88
64_F	75_F	0.568	0.88
23_V	83_F	0.566	0.88
54_S	429_K	0.566	0.88
98_E	154_R	0.565	0.88
53_T	56_N	0.565	0.88
95_N	151_F	0.564	0.87
338_S	372_G	0.562	0.87
363_P	410_I	0.562	0.87
252_E	314_T	0.562	0.87
261_S	356_L	0.562	0.87
229_G	365_F	0.560	0.87
74_L	418_I	0.560	0.87
365_F	413_T	0.559	0.87
217_K	220_H	0.557	0.87
421_V	428_M	0.557	0.87
36_T	128_S	0.556	0.87
356_L	364_L	0.555	0.87
212_S	264_Q	0.554	0.87
202_Y	280_N	0.554	0.87
235_T	310_M	0.554	0.87
41_P	58_Y	0.553	0.86
416_G	420_L	0.552	0.86
164_Q	224_P	0.551	0.86
26_A	32_K	0.550	0.86
135_G	138_K	0.550	0.86
27_Y	42_N	0.550	0.86
80_F	121_I	0.549	0.86
307_Y	368_E	0.549	0.86
83_F	116_L	0.549	0.86
135_G	151_F	0.548	0.86
18_V	64_F	0.548	0.86
431_R	436_Y	0.548	0.86
175_E	307_Y	0.547	0.86
60_N	66_H	0.545	0.86
28_N	59_H	0.545	0.86
389_I	393_R	0.539	0.85
11_G	81_K	0.539	0.85
231_M	301_Y	0.538	0.85
210_V	293_L	0.538	0.85
41_P	52_M	0.535	0.85
127_I	156_A	0.535	0.85
253_N	256_K	0.535	0.85
338_S	373_A	0.533	0.84
184_F	195_E	0.533	0.84
351_I	354_N	0.530	0.84
114_D	118_K	0.529	0.84
184_F	204_A	0.529	0.84
53_T	429_K	0.528	0.84
335_L	343_Q	0.528	0.84
238_Y	345_D	0.527	0.84
367_V	410_I	0.527	0.84
337_S	341_G	0.526	0.84
64_F	72_I	0.525	0.84
116_L	123_P	0.524	0.83
124_V	410_I	0.524	0.83
172_T	215_A	0.523	0.83
193_E	197_K	0.522	0.83
383_I	436_Y	0.522	0.83
75_F	83_F	0.521	0.83
210_V	294_L	0.521	0.83
77_E	456_N	0.521	0.83
371_L	375_D	0.520	0.83
143_W	173_F	0.520	0.83
136_L	148_V	0.519	0.83
52_M	421_V	0.519	0.83
313_S	330_V	0.518	0.83
286_M	289_G	0.518	0.83
67_R	446_T	0.518	0.83
194_G	197_K	0.517	0.83
392_L	396_L	0.515	0.82
246_D	249_A	0.515	0.82
126_T	231_M	0.515	0.82
440_D	448_N	0.513	0.82
64_F	68_Y	0.512	0.82
30_G	102_N	0.511	0.82
44_I	51_S	0.511	0.82
435_I	455_F	0.510	0.82
216_V	297_H	0.510	0.82
261_S	265_A	0.509	0.82
98_E	101_P	0.509	0.82
397_I	400_R	0.509	0.82
258_L	272_Y	0.509	0.82
18_V	420_L	0.508	0.81
21_N	41_P	0.508	0.81
216_V	219_G	0.507	0.81
140_Y	145_N	0.505	0.81
392_L	458_Y	0.505	0.81
37_A	423_A	0.504	0.81
303_G	367_V	0.504	0.81
37_A	40_S	0.504	0.81
398_E	405_D	0.503	0.81
32_K	131_E	0.503	0.81
266_R	360_Y	0.503	0.81
278_A	283_E	0.502	0.81
338_S	341_G	0.502	0.81
286_M	290_D	0.501	0.81
456_N	463_A	0.501	0.81
39_V	43_G	0.500	0.80

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1v02A	2	0.9552	100	0.112	Contact Map
2dgaA	5	0.9616	100	0.114	Contact Map
3ptmA	1	0.9552	100	0.115	Contact Map
2jf7A	5	0.9424	100	0.118	Contact Map
1v08A	2	0.9574	100	0.118	Contact Map
3wq5A	1	0.9552	100	0.119	Contact Map
1cbgA	2	0.9574	100	0.121	Contact Map
3w53A	1	0.9574	100	0.122	Contact Map
3f5lA	2	0.9531	100	0.126	Contact Map
4iplA	2	0.9574	100	0.127	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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