PTV3B - BACSU - GREMLIN Contacts

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PTV3B - PTS system beta-glucoside-specific EIIBCA component

UniProt:	P40739	Sequences: MDYDKLSKDILQLVGGEENVQRVIHCMTRLRFNLHDNAKADRSQLEQLPGVMGTNISGEQFQIIIGNDVPKVYQAIVRHSNLSDEKSAGSSSQKKNVLSAVFDVISGVFTPILPAIAGAGMIKGLVALAVTFGWMAEKSQVHVILTAVGDGAFYFLPLLLAMSAARKFGSNPYVAAAIAAAILHPDLTALLGAGKPISFIGLPVTAATYSSTVIPILLSIWIASYVEKWIDRFTHASLKLIVVPTFTLLIVVPLTLITVGPLGAILGEYLSSGVNYLFDHAGLVAMILLAGTFSLIIMTGMHYAFVPIMINNIAQNGHDYLLPAMFLANMGQAGASFAVFLRSRNKKFKSLALTTSITALMGITEPAMYGVNMRLKKPFAAALIGGAAGGAFYGMTGVASYIVGGNAGLPSIPVFIGPTFIYAMIGLVIAFAAGTAAAYLLGFEDVPSDGSQQPAVHEGSREIIHSPIKGEVKALSEVKDGVFSAGVMGKGFAIEPEEGEVVSPVRGSVTTIFKTKHAIGITSDQGAEILIHIGLDTVKLEGQWFTAHIKEGDKVAPGDPLVSFDLEQIKAAGYDVITPVIVTNTDQYSFSPVKEIGKVQPKEALLALS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	609 (605)
Sequences:	1574 (1186)
Seq/√Len:	48.2

ECOLI - PTV3B PTIBC PTTBC PTYBC
BACSU - PTV3B PTSBC PTXBC PTTBC SACX

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
533_I	562_V	5.645	1.00
486_G	490_K	5.095	1.00
506_R	556_A	4.370	1.00
524_D	554_K	4.328	1.00
550_K	553_D	4.286	1.00
505_V	523_S	4.169	1.00
548_H	560_P	3.882	1.00
544_W	568_Q	3.864	1.00
510_T	522_T	3.775	1.00
500_E	560_P	3.691	1.00
546_T	563_S	3.619	1.00
385_G	433_A	3.549	1.00
338_A	435_T	3.349	1.00
543_Q	572_A	3.319	1.00
499_G	566_L	3.303	1.00
469_K	498_E	3.248	1.00
479_K	575_D	3.138	1.00
505_V	521_I	3.105	1.00
548_H	563_S	3.088	1.00
500_E	563_S	3.070	1.00
219_S	255_T	3.034	1.00
553_D	559_D	3.024	1.00
392_F	429_I	2.972	1.00
468_I	501_V	2.936	1.00
41_D	44_Q	2.858	1.00
291_G	387_A	2.791	1.00
502_V	560_P	2.780	1.00
539_K	574_Y	2.728	1.00
5_K	9_D	2.701	1.00
95_K	100_A	2.688	1.00
501_V	531_I	2.660	1.00
506_R	557_P	2.657	1.00
495_E	575_D	2.657	1.00
161_A	175_A	2.618	1.00
312_N	319_D	2.618	1.00
556_A	559_D	2.607	1.00
466_S	494_I	2.584	1.00
566_L	570_K	2.582	1.00
223_A	247_T	2.563	1.00
11_L	76_I	2.557	1.00
509_V	521_I	2.546	1.00
516_K	547_A	2.537	1.00
478_V	493_A	2.528	1.00
568_Q	571_A	2.516	1.00
566_L	576_V	2.482	1.00
13_L	41_D	2.452	1.00
37_N	56_I	2.428	1.00
508_S	554_K	2.419	1.00
2_D	5_K	2.358	1.00
230_I	246_F	2.348	1.00
53_G	64_I	2.332	1.00
162_M	176_A	2.295	1.00
392_F	422_Y	2.244	1.00
564_F	569_I	2.234	1.00
473_K	577_I	2.231	1.00
507_G	521_I	2.220	1.00
476_S	486_G	2.219	1.00
512_I	547_A	2.214	1.00
468_I	578_T	2.199	1.00
471_E	495_E	2.182	1.00
388_A	433_A	2.179	1.00
568_Q	572_A	2.152	1.00
246_F	250_I	2.147	1.00
479_K	577_I	2.144	1.00
495_E	570_K	2.126	1.00
540_L	544_W	2.124	1.00
42_R	61_F	2.114	1.00
535_L	579_P	2.110	1.00
45_L	48_L	2.078	1.00
290_A	386_G	2.075	1.00
465_H	557_P	2.056	1.00
17_E	81_N	2.036	1.00
502_V	601_P	2.005	0.99
576_V	579_P	1.987	0.99
490_K	590_F	1.983	0.99
543_Q	568_Q	1.971	0.99
4_D	8_K	1.962	0.99
6_L	48_L	1.959	0.99
43_S	46_E	1.957	0.99
49_P	347_K	1.949	0.99
125_L	129_A	1.946	0.99
464_I	505_V	1.939	0.99
276_Y	280_H	1.933	0.99
529_I	582_V	1.933	0.99
337_F	356_S	1.932	0.99
162_M	172_P	1.916	0.99
381_A	441_L	1.912	0.99
462_E	527_A	1.897	0.99
158_L	180_A	1.885	0.99
536_D	539_K	1.880	0.99
75_A	78_R	1.878	0.99
34_L	40_A	1.869	0.99
104_V	168_F	1.827	0.99
567_E	571_A	1.826	0.99
560_P	563_S	1.824	0.99
506_R	524_D	1.816	0.99
512_I	551_E	1.816	0.99
42_R	56_I	1.815	0.99
436_A	440_L	1.806	0.99
103_D	167_K	1.799	0.99
567_E	570_K	1.787	0.99
343_S	348_F	1.786	0.99
332_Q	372_N	1.778	0.99
474_A	477_E	1.773	0.99
20_V	80_S	1.744	0.99
158_L	176_A	1.728	0.98
393_Y	426_G	1.724	0.98
23_V	76_I	1.720	0.98
544_W	572_A	1.711	0.98
166_R	172_P	1.680	0.98
36_D	39_K	1.669	0.98
333_A	359_A	1.663	0.98
500_E	548_H	1.654	0.98
334_G	431_F	1.652	0.98
13_L	44_Q	1.649	0.98
505_V	529_I	1.643	0.98
396_T	422_Y	1.638	0.98
144_I	204_V	1.623	0.98
231_D	239_K	1.611	0.98
424_M	428_V	1.604	0.97
161_A	179_A	1.592	0.97
21_Q	35_H	1.584	0.97
222_I	254_L	1.578	0.97
97_V	100_A	1.571	0.97
462_E	525_Q	1.568	0.97
368_M	379_F	1.568	0.97
9_D	48_L	1.566	0.97
218_L	263_G	1.566	0.97
482_V	487_V	1.566	0.97
599_V	603_E	1.563	0.97
469_K	601_P	1.561	0.97
165_A	220_I	1.559	0.97
469_K	497_E	1.554	0.97
501_V	564_F	1.534	0.97
544_W	574_Y	1.533	0.97
503_S	506_R	1.530	0.97
23_V	32_F	1.530	0.97
20_V	82_L	1.515	0.96
327_L	393_Y	1.513	0.96
486_G	585_T	1.507	0.96
516_K	548_H	1.503	0.96
508_S	522_T	1.499	0.96
226_V	251_V	1.499	0.96
129_A	134_W	1.496	0.96
493_A	577_I	1.482	0.96
540_L	543_Q	1.479	0.96
492_F	605_L	1.470	0.96
8_K	12_Q	1.461	0.96
495_E	576_V	1.459	0.96
472_V	492_F	1.453	0.95
585_T	591_S	1.445	0.95
42_R	46_E	1.443	0.95
580_V	605_L	1.443	0.95
468_I	579_P	1.430	0.95
334_G	434_G	1.400	0.94
163_S	173_Y	1.399	0.94
73_Y	77_V	1.399	0.94
375_L	443_F	1.393	0.94
498_E	566_L	1.388	0.94
179_A	216_I	1.384	0.94
469_K	600_Q	1.377	0.94
32_F	63_I	1.376	0.94
503_S	557_P	1.375	0.94
340_F	353_L	1.368	0.94
238_L	242_V	1.368	0.94
512_I	516_K	1.367	0.94
326_F	423_A	1.352	0.93
498_E	564_F	1.347	0.93
354_T	358_T	1.327	0.93
482_V	488_M	1.325	0.93
165_A	175_A	1.324	0.93
13_L	48_L	1.321	0.92
122_I	149_G	1.314	0.92
109_F	213_V	1.313	0.92
318_H	399_A	1.309	0.92
97_V	101_V	1.308	0.92
123_K	150_D	1.307	0.92
268_E	272_S	1.303	0.92
170_S	220_I	1.302	0.92
274_V	320_Y	1.292	0.92
392_F	396_T	1.287	0.91
222_I	259_V	1.285	0.91
348_F	375_L	1.283	0.91
112_I	163_S	1.282	0.91
14_V	34_L	1.278	0.91
516_K	546_T	1.277	0.91
345_N	348_F	1.276	0.91
22_R	33_N	1.272	0.91
151_G	180_A	1.269	0.91
119_A	152_A	1.269	0.91
281_A	284_V	1.263	0.91
569_I	572_A	1.255	0.90
263_G	267_G	1.253	0.90
326_F	411_S	1.244	0.90
112_I	156_L	1.244	0.90
499_G	567_E	1.244	0.90
25_H	73_Y	1.242	0.90
75_A	79_H	1.241	0.90
509_V	519_I	1.234	0.90
294_S	329_N	1.225	0.89
548_H	559_D	1.217	0.89
119_A	151_G	1.215	0.89
4_D	75_A	1.215	0.89
519_I	562_V	1.214	0.89
463_I	604_A	1.211	0.89
108_V	217_L	1.204	0.88
471_E	497_E	1.198	0.88
286_M	290_A	1.198	0.88
380_A	384_I	1.190	0.88
296_I	305_F	1.181	0.87
540_L	579_P	1.173	0.87
589_S	592_P	1.171	0.87
221_W	224_S	1.164	0.87
547_A	562_V	1.164	0.87
432_A	436_A	1.162	0.87
600_Q	603_E	1.147	0.86
388_A	429_I	1.145	0.86
181_A	252_V	1.145	0.86
473_K	478_V	1.144	0.86
527_A	588_Y	1.135	0.85
472_V	605_L	1.131	0.85
231_D	243_V	1.128	0.85
473_K	495_E	1.127	0.85
221_W	225_Y	1.120	0.84
540_L	568_Q	1.117	0.84
471_E	598_K	1.114	0.84
175_A	179_A	1.113	0.84
493_A	579_P	1.112	0.84
422_Y	425_I	1.106	0.84
155_F	185_P	1.105	0.84
505_V	527_A	1.104	0.84
126_V	142_H	1.104	0.84
514_K	541_E	1.102	0.83
204_V	257_I	1.100	0.83
507_G	523_S	1.096	0.83
462_E	523_S	1.092	0.83
170_S	175_A	1.090	0.83
375_L	378_P	1.086	0.83
385_G	434_G	1.082	0.82
481_G	485_A	1.081	0.82
150_D	184_H	1.080	0.82
584_N	588_Y	1.080	0.82
269_Y	273_G	1.073	0.82
339_V	343_S	1.073	0.82
53_G	299_T	1.066	0.81
236_A	239_K	1.055	0.81
592_P	607_A	1.055	0.81
475_L	491_G	1.050	0.80
165_A	172_P	1.049	0.80
594_K	607_A	1.049	0.80
148_V	252_V	1.044	0.80
488_M	581_I	1.042	0.80
336_S	367_A	1.040	0.80
332_Q	364_T	1.039	0.80
516_K	519_I	1.031	0.79
490_K	585_T	1.030	0.79
471_E	597_G	1.028	0.79
122_I	245_T	1.027	0.79
162_M	166_R	1.026	0.79
44_Q	48_L	1.026	0.79
160_L	216_I	1.026	0.79
229_W	233_F	1.026	0.79
298_M	368_M	1.025	0.79
56_I	61_F	1.023	0.79
277_L	288_L	1.014	0.78
509_V	555_V	1.011	0.78
23_V	77_V	1.011	0.78
581_I	585_T	1.009	0.78
392_F	426_G	1.009	0.78
468_I	566_L	1.006	0.77
512_I	562_V	1.004	0.77
164_A	217_L	1.003	0.77
168_F	224_S	1.001	0.77
585_T	588_Y	1.001	0.77
286_M	390_G	1.000	0.77
165_A	170_S	0.993	0.76
492_F	580_V	0.991	0.76
286_M	391_A	0.989	0.76
328_A	332_Q	0.978	0.75
540_L	576_V	0.976	0.75
270_L	296_I	0.975	0.75
521_I	531_I	0.973	0.75
11_L	79_H	0.972	0.75
234_T	242_V	0.972	0.75
287_I	391_A	0.971	0.75
10_I	45_L	0.970	0.75
289_L	305_F	0.969	0.75
377_K	442_G	0.968	0.75
286_M	324_A	0.967	0.75
17_E	80_S	0.966	0.74
349_K	353_L	0.965	0.74
341_L	435_T	0.963	0.74
492_F	593_V	0.963	0.74
478_V	577_I	0.961	0.74
533_I	564_F	0.960	0.74
11_L	80_S	0.959	0.74
381_A	385_G	0.957	0.74
503_S	521_I	0.956	0.74
377_K	444_E	0.953	0.73
389_G	430_A	0.951	0.73
9_D	12_Q	0.948	0.73
497_E	598_K	0.947	0.73
92_S	100_A	0.945	0.73
158_L	179_A	0.945	0.73
338_A	439_Y	0.942	0.73
136_A	139_S	0.941	0.73
510_T	521_I	0.940	0.72
64_I	299_T	0.937	0.72
32_F	76_I	0.936	0.72
121_M	245_T	0.929	0.72
372_N	378_P	0.927	0.71
148_V	181_A	0.926	0.71
461_R	589_S	0.924	0.71
468_I	564_F	0.923	0.71
345_N	445_D	0.921	0.71
154_Y	210_S	0.920	0.71
171_N	227_E	0.916	0.70
506_R	521_I	0.913	0.70
466_S	605_L	0.913	0.70
514_K	551_E	0.912	0.70
501_V	578_T	0.912	0.70
498_E	502_V	0.910	0.70
8_K	79_H	0.909	0.70
183_L	210_S	0.909	0.70
6_L	10_I	0.907	0.70
169_G	228_K	0.906	0.70
168_F	221_W	0.905	0.70
170_S	223_A	0.905	0.70
169_G	175_A	0.903	0.69
121_M	242_V	0.903	0.69
162_M	173_Y	0.903	0.69
392_F	425_I	0.902	0.69
265_I	269_Y	0.900	0.69
468_I	580_V	0.900	0.69
381_A	437_A	0.898	0.69
339_V	443_F	0.897	0.69
334_G	360_L	0.896	0.69
104_V	108_V	0.894	0.69
378_P	438_A	0.893	0.69
472_V	594_K	0.890	0.68
242_V	246_F	0.889	0.68
429_I	433_A	0.889	0.68
389_G	429_I	0.885	0.68
331_G	385_G	0.883	0.68
141_V	200_I	0.882	0.68
128_L	132_F	0.880	0.67
295_L	299_T	0.877	0.67
514_K	533_I	0.876	0.67
466_S	599_V	0.876	0.67
170_S	225_Y	0.875	0.67
509_V	549_I	0.875	0.67
294_S	368_M	0.875	0.67
116_I	303_Y	0.875	0.67
290_A	324_A	0.874	0.67
475_L	478_V	0.874	0.67
469_K	602_K	0.872	0.67
473_K	493_A	0.870	0.66
161_A	220_I	0.870	0.66
334_G	338_A	0.870	0.66
164_A	221_W	0.868	0.66
356_S	360_L	0.867	0.66
285_A	319_D	0.865	0.66
55_N	64_I	0.864	0.66
475_L	486_G	0.862	0.66
433_A	437_A	0.860	0.66
594_K	597_G	0.859	0.65
435_T	439_Y	0.859	0.65
428_V	565_D	0.855	0.65
13_L	45_L	0.853	0.65
98_L	101_V	0.851	0.65
37_N	61_F	0.850	0.65
225_Y	229_W	0.850	0.65
508_S	524_D	0.849	0.65
385_G	389_G	0.846	0.64
499_G	563_S	0.844	0.64
169_G	220_I	0.842	0.64
335_A	372_N	0.840	0.64
379_F	383_L	0.838	0.64
145_L	200_I	0.837	0.63
495_E	577_I	0.836	0.63
295_L	383_L	0.835	0.63
512_I	519_I	0.830	0.63
547_A	551_E	0.830	0.63
335_A	382_A	0.825	0.62
226_V	250_I	0.825	0.62
476_S	529_I	0.821	0.62
262_L	267_G	0.818	0.62
144_I	256_L	0.817	0.62
39_K	543_Q	0.816	0.61
468_I	494_I	0.815	0.61
273_G	277_L	0.814	0.61
199_F	253_P	0.814	0.61
295_L	379_F	0.811	0.61
124_G	286_M	0.811	0.61
225_Y	228_K	0.811	0.61
330_M	333_A	0.810	0.61
6_L	50_G	0.810	0.61
342_R	443_F	0.808	0.61
161_A	176_A	0.808	0.61
65_I	72_V	0.807	0.61
533_I	578_T	0.802	0.60
220_I	224_S	0.802	0.60
348_F	445_D	0.800	0.60
164_A	168_F	0.799	0.60
490_K	588_Y	0.799	0.60
84_D	91_S	0.798	0.60
341_L	439_Y	0.798	0.60
557_P	560_P	0.796	0.60
345_N	446_V	0.794	0.59
398_V	420_F	0.791	0.59
220_I	256_L	0.790	0.59
385_G	388_A	0.789	0.59
7_S	76_I	0.786	0.59
3_Y	68_D	0.783	0.58
271_S	304_A	0.782	0.58
479_K	484_S	0.781	0.58
108_V	168_F	0.778	0.58
161_A	169_G	0.777	0.58
396_T	429_I	0.776	0.58
294_S	379_F	0.774	0.57
45_L	61_F	0.773	0.57
271_S	305_F	0.773	0.57
385_G	437_A	0.771	0.57
340_F	349_K	0.771	0.57
464_I	580_V	0.771	0.57
561_L	582_V	0.770	0.57
384_I	437_A	0.769	0.57
335_A	378_P	0.767	0.57
477_E	596_I	0.767	0.57
178_I	248_L	0.767	0.57
342_R	377_K	0.766	0.57
412_I	427_L	0.764	0.56
566_L	569_I	0.763	0.56
68_D	71_K	0.762	0.56
570_K	576_V	0.761	0.56
330_M	431_F	0.760	0.56
468_I	576_V	0.759	0.56
398_V	426_G	0.757	0.56
178_I	182_I	0.757	0.56
181_A	256_L	0.756	0.56
548_H	562_V	0.755	0.56
204_V	541_E	0.753	0.55
336_S	340_F	0.752	0.55
332_Q	382_A	0.752	0.55
27_M	407_A	0.751	0.55
500_E	601_P	0.750	0.55
14_V	40_A	0.748	0.55
463_I	605_L	0.746	0.55
354_T	363_I	0.746	0.55
230_I	234_T	0.745	0.55
391_A	395_M	0.745	0.55
96_N	99_S	0.745	0.55
599_V	605_L	0.744	0.54
7_S	79_H	0.742	0.54
585_T	589_S	0.741	0.54
339_V	378_P	0.741	0.54
159_L	180_A	0.741	0.54
482_V	539_K	0.740	0.54
390_G	413_P	0.738	0.54
523_S	555_V	0.738	0.54
170_S	227_E	0.738	0.54
77_V	82_L	0.736	0.54
152_A	159_L	0.735	0.54
101_V	104_V	0.735	0.54
124_G	294_S	0.735	0.54
419_T	422_Y	0.733	0.53
162_M	171_N	0.732	0.53
437_A	441_L	0.730	0.53
294_S	383_L	0.729	0.53
222_I	251_V	0.728	0.53
336_S	372_N	0.727	0.53
465_H	602_K	0.727	0.53
401_Y	416_I	0.725	0.53
119_A	245_T	0.725	0.53
283_L	395_M	0.725	0.53
381_A	438_A	0.725	0.53
234_T	243_V	0.724	0.52
430_A	434_G	0.721	0.52
4_D	78_R	0.721	0.52
199_F	204_V	0.718	0.52
320_Y	323_P	0.718	0.52
178_I	219_S	0.716	0.52
372_N	382_A	0.714	0.51
76_I	80_S	0.713	0.51
569_I	574_Y	0.712	0.51
342_R	349_K	0.712	0.51
187_L	191_L	0.710	0.51
118_G	179_A	0.709	0.51
27_M	363_I	0.708	0.51
311_N	315_Q	0.708	0.51
521_I	591_S	0.707	0.51
421_I	424_M	0.705	0.50
39_K	45_L	0.705	0.50
102_F	373_M	0.705	0.50
348_F	371_V	0.705	0.50
11_L	20_V	0.704	0.50
407_A	411_S	0.703	0.50
499_G	560_P	0.703	0.50
322_L	403_V	0.702	0.50
187_L	256_L	0.701	0.50
501_V	533_I	0.701	0.50
10_I	65_I	0.701	0.50
388_A	392_F	0.700	0.50
540_L	574_Y	0.700	0.50
178_I	216_I	0.700	0.50
594_K	605_L	0.700	0.50
333_A	356_S	0.699	0.50
234_T	238_L	0.699	0.50
106_S	303_Y	0.699	0.50
289_L	296_I	0.698	0.50
123_K	184_H	0.697	0.50
45_L	63_I	0.695	0.49
461_R	607_A	0.694	0.49
159_L	177_A	0.694	0.49
512_I	605_L	0.694	0.49
309_M	319_D	0.694	0.49
528_E	583_T	0.693	0.49
145_L	199_F	0.692	0.49
477_E	497_E	0.692	0.49
74_Q	169_G	0.692	0.49
147_A	184_H	0.691	0.49
267_G	301_M	0.691	0.49
472_V	599_V	0.690	0.49
40_A	61_F	0.690	0.49
37_N	59_E	0.689	0.49
389_G	431_F	0.689	0.49
143_V	190_L	0.687	0.49
121_M	124_G	0.687	0.49
478_V	575_D	0.685	0.48
511_T	539_K	0.685	0.48
335_A	381_A	0.685	0.48
305_F	309_M	0.685	0.48
452_Q	458_E	0.683	0.48
141_V	199_F	0.683	0.48
479_K	535_L	0.680	0.48
431_F	434_G	0.679	0.48
212_T	216_I	0.679	0.48
91_S	100_A	0.679	0.48
404_G	414_V	0.678	0.48
520_G	583_T	0.677	0.48
46_E	374_R	0.676	0.48
48_L	51_V	0.675	0.47
393_Y	398_V	0.675	0.47
283_L	391_A	0.674	0.47
464_I	603_E	0.672	0.47
306_V	309_M	0.671	0.47
334_G	433_A	0.671	0.47
588_Y	591_S	0.670	0.47
398_V	422_Y	0.668	0.47
492_F	606_L	0.668	0.47
400_S	414_V	0.665	0.46
108_V	124_G	0.664	0.46
160_L	213_V	0.663	0.46
292_T	383_L	0.660	0.46
128_L	131_T	0.659	0.46
522_T	586_D	0.659	0.46
290_A	414_V	0.659	0.46
497_E	566_L	0.659	0.46
274_V	308_I	0.659	0.46
343_S	375_L	0.657	0.46
14_V	32_F	0.656	0.46
582_V	591_S	0.655	0.45
478_V	491_G	0.651	0.45
266_L	269_Y	0.651	0.45
581_I	588_Y	0.650	0.45
283_L	287_I	0.649	0.45
401_Y	423_A	0.648	0.45
27_M	55_N	0.648	0.45
339_V	375_L	0.648	0.45
239_K	243_V	0.647	0.45
454_P	457_H	0.647	0.45
328_A	368_M	0.647	0.45
325_M	329_N	0.647	0.45
503_S	523_S	0.646	0.45
473_K	479_K	0.646	0.45
539_K	563_S	0.644	0.44
45_L	51_V	0.643	0.44
567_E	600_Q	0.642	0.44
27_M	109_F	0.640	0.44
322_L	400_S	0.640	0.44
529_I	601_P	0.639	0.44
338_A	438_A	0.639	0.44
107_G	167_K	0.639	0.44
273_G	276_Y	0.639	0.44
96_N	100_A	0.638	0.44
226_V	230_I	0.638	0.44
238_L	434_G	0.638	0.44
238_L	361_M	0.638	0.44
565_D	568_Q	0.637	0.44
328_A	364_T	0.636	0.44
161_A	170_S	0.636	0.44
209_Y	215_P	0.636	0.44
343_S	445_D	0.635	0.43
507_G	557_P	0.635	0.43
479_K	495_E	0.634	0.43
94_K	100_A	0.634	0.43
510_T	529_I	0.631	0.43
76_I	81_N	0.630	0.43
175_A	220_I	0.630	0.43
18_E	39_K	0.629	0.43
323_P	404_G	0.628	0.43
444_E	447_P	0.627	0.43
332_Q	367_A	0.627	0.43
294_S	328_A	0.627	0.43
523_S	527_A	0.627	0.43
40_A	54_T	0.627	0.43
494_I	580_V	0.625	0.42
403_V	406_N	0.625	0.42
12_Q	41_D	0.625	0.42
407_A	414_V	0.622	0.42
42_R	54_T	0.622	0.42
452_Q	456_V	0.620	0.42
371_V	375_L	0.619	0.42
452_Q	459_G	0.619	0.42
576_V	580_V	0.618	0.42
138_K	142_H	0.617	0.42
328_A	382_A	0.616	0.42
585_T	606_L	0.616	0.42
194_G	197_I	0.616	0.42
356_S	359_A	0.615	0.42
315_Q	318_H	0.615	0.42
345_N	448_S	0.614	0.41
6_L	72_V	0.613	0.41
2_D	68_D	0.612	0.41
342_R	444_E	0.612	0.41
335_A	385_G	0.612	0.41
364_T	367_A	0.612	0.41
150_D	239_K	0.611	0.41
36_D	45_L	0.610	0.41
492_F	495_E	0.610	0.41
469_K	500_E	0.609	0.41
5_K	8_K	0.609	0.41
214_I	263_G	0.609	0.41
539_K	570_K	0.609	0.41
191_L	210_S	0.607	0.41
241_I	410_P	0.607	0.41
490_K	591_S	0.606	0.41
23_V	513_F	0.605	0.41
327_L	430_A	0.605	0.41
21_Q	33_N	0.605	0.41
533_I	547_A	0.603	0.40
471_E	498_E	0.602	0.40
488_M	583_T	0.602	0.40
328_A	386_G	0.602	0.40
547_A	553_D	0.602	0.40
597_G	607_A	0.601	0.40
597_G	606_L	0.601	0.40
199_F	257_I	0.600	0.40
471_E	479_K	0.600	0.40
161_A	335_A	0.600	0.40
531_I	579_P	0.600	0.40
563_S	576_V	0.599	0.40
9_D	44_Q	0.599	0.40
191_L	379_F	0.599	0.40
240_L	243_V	0.599	0.40
151_G	177_A	0.597	0.40
241_I	407_A	0.596	0.40
44_Q	47_Q	0.595	0.40
337_F	340_F	0.592	0.39
510_T	586_D	0.592	0.39
485_A	577_I	0.592	0.39
492_F	544_W	0.592	0.39
119_A	240_L	0.591	0.39
293_F	305_F	0.591	0.39
533_I	589_S	0.591	0.39
278_F	285_A	0.591	0.39
516_K	544_W	0.590	0.39
294_S	372_N	0.590	0.39
340_F	352_A	0.590	0.39
99_S	103_D	0.590	0.39
52_M	64_I	0.588	0.39
329_N	367_A	0.587	0.39
140_Q	198_S	0.587	0.39
337_F	341_L	0.587	0.39
14_V	63_I	0.586	0.39
70_P	145_L	0.586	0.39
248_L	391_A	0.586	0.39
214_I	219_S	0.585	0.39
339_V	442_G	0.584	0.39
508_S	551_E	0.584	0.39
116_I	381_A	0.584	0.39
529_I	576_V	0.582	0.38
353_L	357_I	0.582	0.38
161_A	183_L	0.582	0.38
241_I	327_L	0.582	0.38
254_L	445_D	0.581	0.38
581_I	587_Q	0.581	0.38
171_N	363_I	0.580	0.38
126_V	129_A	0.580	0.38
127_A	400_S	0.579	0.38
130_V	142_H	0.579	0.38
535_L	576_V	0.579	0.38
449_D	456_V	0.578	0.38
571_A	596_I	0.578	0.38
118_G	330_M	0.578	0.38
278_F	324_A	0.578	0.38
288_L	292_T	0.578	0.38
329_N	382_A	0.578	0.38
163_S	361_M	0.578	0.38
329_N	372_N	0.578	0.38
84_D	88_A	0.575	0.38
466_S	598_K	0.575	0.38
151_G	179_A	0.574	0.38
291_G	295_L	0.574	0.38
487_V	514_K	0.574	0.38
125_L	238_L	0.574	0.38
494_I	569_I	0.573	0.37
309_M	406_N	0.573	0.37
488_M	511_T	0.573	0.37
527_A	584_N	0.571	0.37
259_V	273_G	0.570	0.37
401_Y	418_P	0.570	0.37
556_A	570_K	0.570	0.37
126_V	146_T	0.569	0.37
4_D	508_S	0.568	0.37
70_P	74_Q	0.568	0.37
68_D	236_A	0.567	0.37
71_K	231_D	0.567	0.37
285_A	312_N	0.566	0.37
343_S	371_V	0.565	0.37
329_N	408_G	0.565	0.37
529_I	588_Y	0.564	0.37
465_H	604_A	0.564	0.37
47_Q	582_V	0.564	0.37
368_M	382_A	0.564	0.37
288_L	463_I	0.564	0.37
20_V	598_K	0.564	0.37
84_D	90_S	0.563	0.37
511_T	551_E	0.563	0.37
421_I	425_I	0.562	0.36
403_V	408_G	0.562	0.36
101_V	472_V	0.561	0.36
421_I	546_T	0.561	0.36
266_L	301_M	0.561	0.36
562_V	579_P	0.561	0.36
464_I	527_A	0.560	0.36
293_F	303_Y	0.560	0.36
198_S	484_S	0.560	0.36
401_Y	417_G	0.559	0.36
332_Q	383_L	0.559	0.36
311_N	314_A	0.558	0.36
141_V	203_P	0.558	0.36
88_A	91_S	0.558	0.36
513_F	541_E	0.558	0.36
116_I	181_A	0.558	0.36
453_Q	471_E	0.557	0.36
468_I	605_L	0.556	0.36
464_I	529_I	0.555	0.36
192_G	284_V	0.554	0.36
385_G	411_S	0.554	0.36
359_A	364_T	0.554	0.36
464_I	523_S	0.554	0.36
154_Y	160_L	0.552	0.36
475_L	579_P	0.552	0.36
12_Q	600_Q	0.552	0.36
359_A	367_A	0.551	0.35
114_P	329_N	0.551	0.35
466_S	579_P	0.551	0.35
145_L	249_L	0.550	0.35
34_L	61_F	0.549	0.35
551_E	586_D	0.549	0.35
326_F	329_N	0.548	0.35
140_Q	199_F	0.548	0.35
132_F	135_M	0.548	0.35
331_G	382_A	0.548	0.35
279_D	603_E	0.548	0.35
35_H	61_F	0.548	0.35
485_A	516_K	0.547	0.35
457_H	582_V	0.547	0.35
473_K	575_D	0.547	0.35
533_I	604_A	0.546	0.35
209_Y	364_T	0.546	0.35
492_F	595_E	0.545	0.35
481_G	488_M	0.545	0.35
151_G	154_Y	0.545	0.35
497_E	548_H	0.545	0.35
322_L	407_A	0.544	0.35
125_L	128_L	0.544	0.35
313_I	403_V	0.542	0.35
422_Y	429_I	0.542	0.35
286_M	394_G	0.542	0.35
124_G	406_N	0.542	0.35
469_K	599_V	0.541	0.35
466_S	492_F	0.541	0.35
189_A	193_A	0.540	0.34
455_A	476_S	0.540	0.34
454_P	466_S	0.539	0.34
43_S	47_Q	0.539	0.34
531_I	580_V	0.539	0.34
169_G	179_A	0.538	0.34
140_Q	143_V	0.538	0.34
224_S	228_K	0.538	0.34
519_I	555_V	0.538	0.34
543_Q	574_Y	0.537	0.34
93_Q	96_N	0.537	0.34
493_A	575_D	0.536	0.34
460_S	590_F	0.536	0.34
51_V	65_I	0.535	0.34
388_A	500_E	0.535	0.34
513_F	562_V	0.535	0.34
354_T	411_S	0.534	0.34
453_Q	456_V	0.534	0.34
351_L	355_T	0.533	0.34
394_G	420_F	0.533	0.34
363_I	407_A	0.533	0.34
251_V	255_T	0.533	0.34
556_A	587_Q	0.533	0.34
230_I	243_V	0.532	0.34
440_L	451_S	0.532	0.34
255_T	582_V	0.532	0.34
154_Y	211_S	0.532	0.34
289_L	321_L	0.531	0.34
464_I	506_R	0.531	0.34
511_T	520_G	0.531	0.34
267_G	270_L	0.530	0.34
468_I	476_S	0.530	0.34
12_Q	570_K	0.529	0.33
154_Y	188_T	0.529	0.33
177_A	248_L	0.529	0.33
486_G	491_G	0.529	0.33
515_T	533_I	0.529	0.33
27_M	329_N	0.529	0.33
293_F	329_N	0.528	0.33
27_M	406_N	0.528	0.33
178_I	252_V	0.528	0.33
23_V	488_M	0.528	0.33
169_G	172_P	0.527	0.33
372_N	379_F	0.527	0.33
467_P	580_V	0.526	0.33
380_A	383_L	0.526	0.33
108_V	227_E	0.526	0.33
233_F	284_V	0.525	0.33
205_T	264_A	0.525	0.33
218_L	259_V	0.525	0.33
477_E	554_K	0.524	0.33
115_A	415_F	0.524	0.33
152_A	374_R	0.524	0.33
114_P	117_A	0.524	0.33
505_V	516_K	0.524	0.33
493_A	578_T	0.523	0.33
332_Q	359_A	0.523	0.33
126_V	245_T	0.522	0.33
12_Q	18_E	0.522	0.33
115_A	174_V	0.522	0.33
243_V	407_A	0.522	0.33
109_F	124_G	0.521	0.33
117_A	375_L	0.521	0.33
565_D	578_T	0.521	0.33
299_T	303_Y	0.520	0.33
478_V	484_S	0.520	0.33
309_M	403_V	0.520	0.33
482_V	551_E	0.519	0.33
32_F	65_I	0.518	0.32
437_A	440_L	0.517	0.32
407_A	410_P	0.517	0.32
130_V	137_E	0.517	0.32
450_G	577_I	0.516	0.32
168_F	259_V	0.516	0.32
223_A	245_T	0.516	0.32
544_W	564_F	0.516	0.32
106_S	177_A	0.515	0.32
513_F	579_P	0.514	0.32
389_G	426_G	0.514	0.32
516_K	550_K	0.513	0.32
328_A	407_A	0.512	0.32
443_F	446_V	0.512	0.32
509_V	562_V	0.512	0.32
251_V	254_L	0.512	0.32
544_W	547_A	0.512	0.32
454_P	458_E	0.512	0.32
212_T	293_F	0.512	0.32
83_S	288_L	0.511	0.32
173_Y	412_I	0.511	0.32
541_E	572_A	0.511	0.32
333_A	336_S	0.511	0.32
141_V	144_I	0.510	0.32
544_W	588_Y	0.510	0.32
216_I	322_L	0.509	0.32
460_S	525_Q	0.508	0.32
519_I	531_I	0.508	0.32
505_V	555_V	0.508	0.32
116_I	305_F	0.507	0.31
515_T	562_V	0.507	0.31
79_H	229_W	0.507	0.31
162_M	220_I	0.506	0.31
230_I	254_L	0.506	0.31
575_D	579_P	0.506	0.31
356_S	372_N	0.506	0.31
84_D	570_K	0.505	0.31
223_A	329_N	0.505	0.31
454_P	554_K	0.505	0.31
144_I	311_N	0.504	0.31
14_V	48_L	0.504	0.31
500_E	546_T	0.503	0.31
497_E	590_F	0.503	0.31
129_A	159_L	0.503	0.31
469_K	571_A	0.503	0.31
258_T	457_H	0.503	0.31
498_E	590_F	0.503	0.31
425_I	430_A	0.502	0.31
11_L	49_P	0.502	0.31
578_T	602_K	0.502	0.31
330_M	334_G	0.502	0.31
114_P	303_Y	0.501	0.31
303_Y	306_V	0.501	0.31
531_I	578_T	0.500	0.31
303_Y	312_N	0.500	0.31
502_V	557_P	0.500	0.31

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
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HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2gprA	1	0.2529	100	0.759	Contact Map
1f3zA	2	0.243	100	0.76	Contact Map
3ourB	1	0.243	100	0.762	Contact Map
3qnqA	2	0.619	100	0.764	Contact Map
1ax3A	1	0.2627	100	0.766	Contact Map
3ipjA	1	0.1494	100	0.872	Contact Map
1ibaA	1	0.1264	100	0.88	Contact Map
3bp3A	1	0.133	100	0.881	Contact Map
2d5dA	1	0.1149	98.7	0.953	Contact Map
1dczA	1	0.1264	98.6	0.954	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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