GREMLIN Database
PTV3B - PTS system beta-glucoside-specific EIIBCA component
UniProt: P40739 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 609 (605)
Sequences: 1574 (1186)
Seq/√Len: 48.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
533_I562_V5.6451.00
486_G490_K5.0951.00
506_R556_A4.3701.00
524_D554_K4.3281.00
550_K553_D4.2861.00
505_V523_S4.1691.00
548_H560_P3.8821.00
544_W568_Q3.8641.00
510_T522_T3.7751.00
500_E560_P3.6911.00
546_T563_S3.6191.00
385_G433_A3.5491.00
338_A435_T3.3491.00
543_Q572_A3.3191.00
499_G566_L3.3031.00
469_K498_E3.2481.00
479_K575_D3.1381.00
505_V521_I3.1051.00
548_H563_S3.0881.00
500_E563_S3.0701.00
219_S255_T3.0341.00
553_D559_D3.0241.00
392_F429_I2.9721.00
468_I501_V2.9361.00
41_D44_Q2.8581.00
291_G387_A2.7911.00
502_V560_P2.7801.00
539_K574_Y2.7281.00
5_K9_D2.7011.00
95_K100_A2.6881.00
501_V531_I2.6601.00
506_R557_P2.6571.00
495_E575_D2.6571.00
161_A175_A2.6181.00
312_N319_D2.6181.00
556_A559_D2.6071.00
466_S494_I2.5841.00
566_L570_K2.5821.00
223_A247_T2.5631.00
11_L76_I2.5571.00
509_V521_I2.5461.00
516_K547_A2.5371.00
478_V493_A2.5281.00
568_Q571_A2.5161.00
566_L576_V2.4821.00
13_L41_D2.4521.00
37_N56_I2.4281.00
508_S554_K2.4191.00
2_D5_K2.3581.00
230_I246_F2.3481.00
53_G64_I2.3321.00
162_M176_A2.2951.00
392_F422_Y2.2441.00
564_F569_I2.2341.00
473_K577_I2.2311.00
507_G521_I2.2201.00
476_S486_G2.2191.00
512_I547_A2.2141.00
468_I578_T2.1991.00
471_E495_E2.1821.00
388_A433_A2.1791.00
568_Q572_A2.1521.00
246_F250_I2.1471.00
479_K577_I2.1441.00
495_E570_K2.1261.00
540_L544_W2.1241.00
42_R61_F2.1141.00
535_L579_P2.1101.00
45_L48_L2.0781.00
290_A386_G2.0751.00
465_H557_P2.0561.00
17_E81_N2.0361.00
502_V601_P2.0050.99
576_V579_P1.9870.99
490_K590_F1.9830.99
543_Q568_Q1.9710.99
4_D8_K1.9620.99
6_L48_L1.9590.99
43_S46_E1.9570.99
49_P347_K1.9490.99
125_L129_A1.9460.99
464_I505_V1.9390.99
276_Y280_H1.9330.99
529_I582_V1.9330.99
337_F356_S1.9320.99
162_M172_P1.9160.99
381_A441_L1.9120.99
462_E527_A1.8970.99
158_L180_A1.8850.99
536_D539_K1.8800.99
75_A78_R1.8780.99
34_L40_A1.8690.99
104_V168_F1.8270.99
567_E571_A1.8260.99
560_P563_S1.8240.99
506_R524_D1.8160.99
512_I551_E1.8160.99
42_R56_I1.8150.99
436_A440_L1.8060.99
103_D167_K1.7990.99
567_E570_K1.7870.99
343_S348_F1.7860.99
332_Q372_N1.7780.99
474_A477_E1.7730.99
20_V80_S1.7440.99
158_L176_A1.7280.98
393_Y426_G1.7240.98
23_V76_I1.7200.98
544_W572_A1.7110.98
166_R172_P1.6800.98
36_D39_K1.6690.98
333_A359_A1.6630.98
500_E548_H1.6540.98
334_G431_F1.6520.98
13_L44_Q1.6490.98
505_V529_I1.6430.98
396_T422_Y1.6380.98
144_I204_V1.6230.98
231_D239_K1.6110.98
424_M428_V1.6040.97
161_A179_A1.5920.97
21_Q35_H1.5840.97
222_I254_L1.5780.97
97_V100_A1.5710.97
462_E525_Q1.5680.97
368_M379_F1.5680.97
9_D48_L1.5660.97
218_L263_G1.5660.97
482_V487_V1.5660.97
599_V603_E1.5630.97
469_K601_P1.5610.97
165_A220_I1.5590.97
469_K497_E1.5540.97
501_V564_F1.5340.97
544_W574_Y1.5330.97
503_S506_R1.5300.97
23_V32_F1.5300.97
20_V82_L1.5150.96
327_L393_Y1.5130.96
486_G585_T1.5070.96
516_K548_H1.5030.96
508_S522_T1.4990.96
226_V251_V1.4990.96
129_A134_W1.4960.96
493_A577_I1.4820.96
540_L543_Q1.4790.96
492_F605_L1.4700.96
8_K12_Q1.4610.96
495_E576_V1.4590.96
472_V492_F1.4530.95
585_T591_S1.4450.95
42_R46_E1.4430.95
580_V605_L1.4430.95
468_I579_P1.4300.95
334_G434_G1.4000.94
163_S173_Y1.3990.94
73_Y77_V1.3990.94
375_L443_F1.3930.94
498_E566_L1.3880.94
179_A216_I1.3840.94
469_K600_Q1.3770.94
32_F63_I1.3760.94
503_S557_P1.3750.94
340_F353_L1.3680.94
238_L242_V1.3680.94
512_I516_K1.3670.94
326_F423_A1.3520.93
498_E564_F1.3470.93
354_T358_T1.3270.93
482_V488_M1.3250.93
165_A175_A1.3240.93
13_L48_L1.3210.92
122_I149_G1.3140.92
109_F213_V1.3130.92
318_H399_A1.3090.92
97_V101_V1.3080.92
123_K150_D1.3070.92
268_E272_S1.3030.92
170_S220_I1.3020.92
274_V320_Y1.2920.92
392_F396_T1.2870.91
222_I259_V1.2850.91
348_F375_L1.2830.91
112_I163_S1.2820.91
14_V34_L1.2780.91
516_K546_T1.2770.91
345_N348_F1.2760.91
22_R33_N1.2720.91
151_G180_A1.2690.91
119_A152_A1.2690.91
281_A284_V1.2630.91
569_I572_A1.2550.90
263_G267_G1.2530.90
326_F411_S1.2440.90
112_I156_L1.2440.90
499_G567_E1.2440.90
25_H73_Y1.2420.90
75_A79_H1.2410.90
509_V519_I1.2340.90
294_S329_N1.2250.89
548_H559_D1.2170.89
119_A151_G1.2150.89
4_D75_A1.2150.89
519_I562_V1.2140.89
463_I604_A1.2110.89
108_V217_L1.2040.88
471_E497_E1.1980.88
286_M290_A1.1980.88
380_A384_I1.1900.88
296_I305_F1.1810.87
540_L579_P1.1730.87
589_S592_P1.1710.87
221_W224_S1.1640.87
547_A562_V1.1640.87
432_A436_A1.1620.87
600_Q603_E1.1470.86
388_A429_I1.1450.86
181_A252_V1.1450.86
473_K478_V1.1440.86
527_A588_Y1.1350.85
472_V605_L1.1310.85
231_D243_V1.1280.85
473_K495_E1.1270.85
221_W225_Y1.1200.84
540_L568_Q1.1170.84
471_E598_K1.1140.84
175_A179_A1.1130.84
493_A579_P1.1120.84
422_Y425_I1.1060.84
155_F185_P1.1050.84
505_V527_A1.1040.84
126_V142_H1.1040.84
514_K541_E1.1020.83
204_V257_I1.1000.83
507_G523_S1.0960.83
462_E523_S1.0920.83
170_S175_A1.0900.83
375_L378_P1.0860.83
385_G434_G1.0820.82
481_G485_A1.0810.82
150_D184_H1.0800.82
584_N588_Y1.0800.82
269_Y273_G1.0730.82
339_V343_S1.0730.82
53_G299_T1.0660.81
236_A239_K1.0550.81
592_P607_A1.0550.81
475_L491_G1.0500.80
165_A172_P1.0490.80
594_K607_A1.0490.80
148_V252_V1.0440.80
488_M581_I1.0420.80
336_S367_A1.0400.80
332_Q364_T1.0390.80
516_K519_I1.0310.79
490_K585_T1.0300.79
471_E597_G1.0280.79
122_I245_T1.0270.79
162_M166_R1.0260.79
44_Q48_L1.0260.79
160_L216_I1.0260.79
229_W233_F1.0260.79
298_M368_M1.0250.79
56_I61_F1.0230.79
277_L288_L1.0140.78
509_V555_V1.0110.78
23_V77_V1.0110.78
581_I585_T1.0090.78
392_F426_G1.0090.78
468_I566_L1.0060.77
512_I562_V1.0040.77
164_A217_L1.0030.77
168_F224_S1.0010.77
585_T588_Y1.0010.77
286_M390_G1.0000.77
165_A170_S0.9930.76
492_F580_V0.9910.76
286_M391_A0.9890.76
328_A332_Q0.9780.75
540_L576_V0.9760.75
270_L296_I0.9750.75
521_I531_I0.9730.75
11_L79_H0.9720.75
234_T242_V0.9720.75
287_I391_A0.9710.75
10_I45_L0.9700.75
289_L305_F0.9690.75
377_K442_G0.9680.75
286_M324_A0.9670.75
17_E80_S0.9660.74
349_K353_L0.9650.74
341_L435_T0.9630.74
492_F593_V0.9630.74
478_V577_I0.9610.74
533_I564_F0.9600.74
11_L80_S0.9590.74
381_A385_G0.9570.74
503_S521_I0.9560.74
377_K444_E0.9530.73
389_G430_A0.9510.73
9_D12_Q0.9480.73
497_E598_K0.9470.73
92_S100_A0.9450.73
158_L179_A0.9450.73
338_A439_Y0.9420.73
136_A139_S0.9410.73
510_T521_I0.9400.72
64_I299_T0.9370.72
32_F76_I0.9360.72
121_M245_T0.9290.72
372_N378_P0.9270.71
148_V181_A0.9260.71
461_R589_S0.9240.71
468_I564_F0.9230.71
345_N445_D0.9210.71
154_Y210_S0.9200.71
171_N227_E0.9160.70
506_R521_I0.9130.70
466_S605_L0.9130.70
514_K551_E0.9120.70
501_V578_T0.9120.70
498_E502_V0.9100.70
8_K79_H0.9090.70
183_L210_S0.9090.70
6_L10_I0.9070.70
169_G228_K0.9060.70
168_F221_W0.9050.70
170_S223_A0.9050.70
169_G175_A0.9030.69
121_M242_V0.9030.69
162_M173_Y0.9030.69
392_F425_I0.9020.69
265_I269_Y0.9000.69
468_I580_V0.9000.69
381_A437_A0.8980.69
339_V443_F0.8970.69
334_G360_L0.8960.69
104_V108_V0.8940.69
378_P438_A0.8930.69
472_V594_K0.8900.68
242_V246_F0.8890.68
429_I433_A0.8890.68
389_G429_I0.8850.68
331_G385_G0.8830.68
141_V200_I0.8820.68
128_L132_F0.8800.67
295_L299_T0.8770.67
514_K533_I0.8760.67
466_S599_V0.8760.67
170_S225_Y0.8750.67
509_V549_I0.8750.67
294_S368_M0.8750.67
116_I303_Y0.8750.67
290_A324_A0.8740.67
475_L478_V0.8740.67
469_K602_K0.8720.67
473_K493_A0.8700.66
161_A220_I0.8700.66
334_G338_A0.8700.66
164_A221_W0.8680.66
356_S360_L0.8670.66
285_A319_D0.8650.66
55_N64_I0.8640.66
475_L486_G0.8620.66
433_A437_A0.8600.66
594_K597_G0.8590.65
435_T439_Y0.8590.65
428_V565_D0.8550.65
13_L45_L0.8530.65
98_L101_V0.8510.65
37_N61_F0.8500.65
225_Y229_W0.8500.65
508_S524_D0.8490.65
385_G389_G0.8460.64
499_G563_S0.8440.64
169_G220_I0.8420.64
335_A372_N0.8400.64
379_F383_L0.8380.64
145_L200_I0.8370.63
495_E577_I0.8360.63
295_L383_L0.8350.63
512_I519_I0.8300.63
547_A551_E0.8300.63
335_A382_A0.8250.62
226_V250_I0.8250.62
476_S529_I0.8210.62
262_L267_G0.8180.62
144_I256_L0.8170.62
39_K543_Q0.8160.61
468_I494_I0.8150.61
273_G277_L0.8140.61
199_F253_P0.8140.61
295_L379_F0.8110.61
124_G286_M0.8110.61
225_Y228_K0.8110.61
330_M333_A0.8100.61
6_L50_G0.8100.61
342_R443_F0.8080.61
161_A176_A0.8080.61
65_I72_V0.8070.61
533_I578_T0.8020.60
220_I224_S0.8020.60
348_F445_D0.8000.60
164_A168_F0.7990.60
490_K588_Y0.7990.60
84_D91_S0.7980.60
341_L439_Y0.7980.60
557_P560_P0.7960.60
345_N446_V0.7940.59
398_V420_F0.7910.59
220_I256_L0.7900.59
385_G388_A0.7890.59
7_S76_I0.7860.59
3_Y68_D0.7830.58
271_S304_A0.7820.58
479_K484_S0.7810.58
108_V168_F0.7780.58
161_A169_G0.7770.58
396_T429_I0.7760.58
294_S379_F0.7740.57
45_L61_F0.7730.57
271_S305_F0.7730.57
385_G437_A0.7710.57
340_F349_K0.7710.57
464_I580_V0.7710.57
561_L582_V0.7700.57
384_I437_A0.7690.57
335_A378_P0.7670.57
477_E596_I0.7670.57
178_I248_L0.7670.57
342_R377_K0.7660.57
412_I427_L0.7640.56
566_L569_I0.7630.56
68_D71_K0.7620.56
570_K576_V0.7610.56
330_M431_F0.7600.56
468_I576_V0.7590.56
398_V426_G0.7570.56
178_I182_I0.7570.56
181_A256_L0.7560.56
548_H562_V0.7550.56
204_V541_E0.7530.55
336_S340_F0.7520.55
332_Q382_A0.7520.55
27_M407_A0.7510.55
500_E601_P0.7500.55
14_V40_A0.7480.55
463_I605_L0.7460.55
354_T363_I0.7460.55
230_I234_T0.7450.55
391_A395_M0.7450.55
96_N99_S0.7450.55
599_V605_L0.7440.54
7_S79_H0.7420.54
585_T589_S0.7410.54
339_V378_P0.7410.54
159_L180_A0.7410.54
482_V539_K0.7400.54
390_G413_P0.7380.54
523_S555_V0.7380.54
170_S227_E0.7380.54
77_V82_L0.7360.54
152_A159_L0.7350.54
101_V104_V0.7350.54
124_G294_S0.7350.54
419_T422_Y0.7330.53
162_M171_N0.7320.53
437_A441_L0.7300.53
294_S383_L0.7290.53
222_I251_V0.7280.53
336_S372_N0.7270.53
465_H602_K0.7270.53
401_Y416_I0.7250.53
119_A245_T0.7250.53
283_L395_M0.7250.53
381_A438_A0.7250.53
234_T243_V0.7240.52
430_A434_G0.7210.52
4_D78_R0.7210.52
199_F204_V0.7180.52
320_Y323_P0.7180.52
178_I219_S0.7160.52
372_N382_A0.7140.51
76_I80_S0.7130.51
569_I574_Y0.7120.51
342_R349_K0.7120.51
187_L191_L0.7100.51
118_G179_A0.7090.51
27_M363_I0.7080.51
311_N315_Q0.7080.51
521_I591_S0.7070.51
421_I424_M0.7050.50
39_K45_L0.7050.50
102_F373_M0.7050.50
348_F371_V0.7050.50
11_L20_V0.7040.50
407_A411_S0.7030.50
499_G560_P0.7030.50
322_L403_V0.7020.50
187_L256_L0.7010.50
501_V533_I0.7010.50
10_I65_I0.7010.50
388_A392_F0.7000.50
540_L574_Y0.7000.50
178_I216_I0.7000.50
594_K605_L0.7000.50
333_A356_S0.6990.50
234_T238_L0.6990.50
106_S303_Y0.6990.50
289_L296_I0.6980.50
123_K184_H0.6970.50
45_L63_I0.6950.49
461_R607_A0.6940.49
159_L177_A0.6940.49
512_I605_L0.6940.49
309_M319_D0.6940.49
528_E583_T0.6930.49
145_L199_F0.6920.49
477_E497_E0.6920.49
74_Q169_G0.6920.49
147_A184_H0.6910.49
267_G301_M0.6910.49
472_V599_V0.6900.49
40_A61_F0.6900.49
37_N59_E0.6890.49
389_G431_F0.6890.49
143_V190_L0.6870.49
121_M124_G0.6870.49
478_V575_D0.6850.48
511_T539_K0.6850.48
335_A381_A0.6850.48
305_F309_M0.6850.48
452_Q458_E0.6830.48
141_V199_F0.6830.48
479_K535_L0.6800.48
431_F434_G0.6790.48
212_T216_I0.6790.48
91_S100_A0.6790.48
404_G414_V0.6780.48
520_G583_T0.6770.48
46_E374_R0.6760.48
48_L51_V0.6750.47
393_Y398_V0.6750.47
283_L391_A0.6740.47
464_I603_E0.6720.47
306_V309_M0.6710.47
334_G433_A0.6710.47
588_Y591_S0.6700.47
398_V422_Y0.6680.47
492_F606_L0.6680.47
400_S414_V0.6650.46
108_V124_G0.6640.46
160_L213_V0.6630.46
292_T383_L0.6600.46
128_L131_T0.6590.46
522_T586_D0.6590.46
290_A414_V0.6590.46
497_E566_L0.6590.46
274_V308_I0.6590.46
343_S375_L0.6570.46
14_V32_F0.6560.46
582_V591_S0.6550.45
478_V491_G0.6510.45
266_L269_Y0.6510.45
581_I588_Y0.6500.45
283_L287_I0.6490.45
401_Y423_A0.6480.45
27_M55_N0.6480.45
339_V375_L0.6480.45
239_K243_V0.6470.45
454_P457_H0.6470.45
328_A368_M0.6470.45
325_M329_N0.6470.45
503_S523_S0.6460.45
473_K479_K0.6460.45
539_K563_S0.6440.44
45_L51_V0.6430.44
567_E600_Q0.6420.44
27_M109_F0.6400.44
322_L400_S0.6400.44
529_I601_P0.6390.44
338_A438_A0.6390.44
107_G167_K0.6390.44
273_G276_Y0.6390.44
96_N100_A0.6380.44
226_V230_I0.6380.44
238_L434_G0.6380.44
238_L361_M0.6380.44
565_D568_Q0.6370.44
328_A364_T0.6360.44
161_A170_S0.6360.44
209_Y215_P0.6360.44
343_S445_D0.6350.43
507_G557_P0.6350.43
479_K495_E0.6340.43
94_K100_A0.6340.43
510_T529_I0.6310.43
76_I81_N0.6300.43
175_A220_I0.6300.43
18_E39_K0.6290.43
323_P404_G0.6280.43
444_E447_P0.6270.43
332_Q367_A0.6270.43
294_S328_A0.6270.43
523_S527_A0.6270.43
40_A54_T0.6270.43
494_I580_V0.6250.42
403_V406_N0.6250.42
12_Q41_D0.6250.42
407_A414_V0.6220.42
42_R54_T0.6220.42
452_Q456_V0.6200.42
371_V375_L0.6190.42
452_Q459_G0.6190.42
576_V580_V0.6180.42
138_K142_H0.6170.42
328_A382_A0.6160.42
585_T606_L0.6160.42
194_G197_I0.6160.42
356_S359_A0.6150.42
315_Q318_H0.6150.42
345_N448_S0.6140.41
6_L72_V0.6130.41
2_D68_D0.6120.41
342_R444_E0.6120.41
335_A385_G0.6120.41
364_T367_A0.6120.41
150_D239_K0.6110.41
36_D45_L0.6100.41
492_F495_E0.6100.41
469_K500_E0.6090.41
5_K8_K0.6090.41
214_I263_G0.6090.41
539_K570_K0.6090.41
191_L210_S0.6070.41
241_I410_P0.6070.41
490_K591_S0.6060.41
23_V513_F0.6050.41
327_L430_A0.6050.41
21_Q33_N0.6050.41
533_I547_A0.6030.40
471_E498_E0.6020.40
488_M583_T0.6020.40
328_A386_G0.6020.40
547_A553_D0.6020.40
597_G607_A0.6010.40
597_G606_L0.6010.40
199_F257_I0.6000.40
471_E479_K0.6000.40
161_A335_A0.6000.40
531_I579_P0.6000.40
563_S576_V0.5990.40
9_D44_Q0.5990.40
191_L379_F0.5990.40
240_L243_V0.5990.40
151_G177_A0.5970.40
241_I407_A0.5960.40
44_Q47_Q0.5950.40
337_F340_F0.5920.39
510_T586_D0.5920.39
485_A577_I0.5920.39
492_F544_W0.5920.39
119_A240_L0.5910.39
293_F305_F0.5910.39
533_I589_S0.5910.39
278_F285_A0.5910.39
516_K544_W0.5900.39
294_S372_N0.5900.39
340_F352_A0.5900.39
99_S103_D0.5900.39
52_M64_I0.5880.39
329_N367_A0.5870.39
140_Q198_S0.5870.39
337_F341_L0.5870.39
14_V63_I0.5860.39
70_P145_L0.5860.39
248_L391_A0.5860.39
214_I219_S0.5850.39
339_V442_G0.5840.39
508_S551_E0.5840.39
116_I381_A0.5840.39
529_I576_V0.5820.38
353_L357_I0.5820.38
161_A183_L0.5820.38
241_I327_L0.5820.38
254_L445_D0.5810.38
581_I587_Q0.5810.38
171_N363_I0.5800.38
126_V129_A0.5800.38
127_A400_S0.5790.38
130_V142_H0.5790.38
535_L576_V0.5790.38
449_D456_V0.5780.38
571_A596_I0.5780.38
118_G330_M0.5780.38
278_F324_A0.5780.38
288_L292_T0.5780.38
329_N382_A0.5780.38
163_S361_M0.5780.38
329_N372_N0.5780.38
84_D88_A0.5750.38
466_S598_K0.5750.38
151_G179_A0.5740.38
291_G295_L0.5740.38
487_V514_K0.5740.38
125_L238_L0.5740.38
494_I569_I0.5730.37
309_M406_N0.5730.37
488_M511_T0.5730.37
527_A584_N0.5710.37
259_V273_G0.5700.37
401_Y418_P0.5700.37
556_A570_K0.5700.37
126_V146_T0.5690.37
4_D508_S0.5680.37
70_P74_Q0.5680.37
68_D236_A0.5670.37
71_K231_D0.5670.37
285_A312_N0.5660.37
343_S371_V0.5650.37
329_N408_G0.5650.37
529_I588_Y0.5640.37
465_H604_A0.5640.37
47_Q582_V0.5640.37
368_M382_A0.5640.37
288_L463_I0.5640.37
20_V598_K0.5640.37
84_D90_S0.5630.37
511_T551_E0.5630.37
421_I425_I0.5620.36
403_V408_G0.5620.36
101_V472_V0.5610.36
421_I546_T0.5610.36
266_L301_M0.5610.36
562_V579_P0.5610.36
464_I527_A0.5600.36
293_F303_Y0.5600.36
198_S484_S0.5600.36
401_Y417_G0.5590.36
332_Q383_L0.5590.36
311_N314_A0.5580.36
141_V203_P0.5580.36
88_A91_S0.5580.36
513_F541_E0.5580.36
116_I181_A0.5580.36
453_Q471_E0.5570.36
468_I605_L0.5560.36
464_I529_I0.5550.36
192_G284_V0.5540.36
385_G411_S0.5540.36
359_A364_T0.5540.36
464_I523_S0.5540.36
154_Y160_L0.5520.36
475_L579_P0.5520.36
12_Q600_Q0.5520.36
359_A367_A0.5510.35
114_P329_N0.5510.35
466_S579_P0.5510.35
145_L249_L0.5500.35
34_L61_F0.5490.35
551_E586_D0.5490.35
326_F329_N0.5480.35
140_Q199_F0.5480.35
132_F135_M0.5480.35
331_G382_A0.5480.35
279_D603_E0.5480.35
35_H61_F0.5480.35
485_A516_K0.5470.35
457_H582_V0.5470.35
473_K575_D0.5470.35
533_I604_A0.5460.35
209_Y364_T0.5460.35
492_F595_E0.5450.35
481_G488_M0.5450.35
151_G154_Y0.5450.35
497_E548_H0.5450.35
322_L407_A0.5440.35
125_L128_L0.5440.35
313_I403_V0.5420.35
422_Y429_I0.5420.35
286_M394_G0.5420.35
124_G406_N0.5420.35
469_K599_V0.5410.35
466_S492_F0.5410.35
189_A193_A0.5400.34
455_A476_S0.5400.34
454_P466_S0.5390.34
43_S47_Q0.5390.34
531_I580_V0.5390.34
169_G179_A0.5380.34
140_Q143_V0.5380.34
224_S228_K0.5380.34
519_I555_V0.5380.34
543_Q574_Y0.5370.34
93_Q96_N0.5370.34
493_A575_D0.5360.34
460_S590_F0.5360.34
51_V65_I0.5350.34
388_A500_E0.5350.34
513_F562_V0.5350.34
354_T411_S0.5340.34
453_Q456_V0.5340.34
351_L355_T0.5330.34
394_G420_F0.5330.34
363_I407_A0.5330.34
251_V255_T0.5330.34
556_A587_Q0.5330.34
230_I243_V0.5320.34
440_L451_S0.5320.34
255_T582_V0.5320.34
154_Y211_S0.5320.34
289_L321_L0.5310.34
464_I506_R0.5310.34
511_T520_G0.5310.34
267_G270_L0.5300.34
468_I476_S0.5300.34
12_Q570_K0.5290.33
154_Y188_T0.5290.33
177_A248_L0.5290.33
486_G491_G0.5290.33
515_T533_I0.5290.33
27_M329_N0.5290.33
293_F329_N0.5280.33
27_M406_N0.5280.33
178_I252_V0.5280.33
23_V488_M0.5280.33
169_G172_P0.5270.33
372_N379_F0.5270.33
467_P580_V0.5260.33
380_A383_L0.5260.33
108_V227_E0.5260.33
233_F284_V0.5250.33
205_T264_A0.5250.33
218_L259_V0.5250.33
477_E554_K0.5240.33
115_A415_F0.5240.33
152_A374_R0.5240.33
114_P117_A0.5240.33
505_V516_K0.5240.33
493_A578_T0.5230.33
332_Q359_A0.5230.33
126_V245_T0.5220.33
12_Q18_E0.5220.33
115_A174_V0.5220.33
243_V407_A0.5220.33
109_F124_G0.5210.33
117_A375_L0.5210.33
565_D578_T0.5210.33
299_T303_Y0.5200.33
478_V484_S0.5200.33
309_M403_V0.5200.33
482_V551_E0.5190.33
32_F65_I0.5180.32
437_A440_L0.5170.32
407_A410_P0.5170.32
130_V137_E0.5170.32
450_G577_I0.5160.32
168_F259_V0.5160.32
223_A245_T0.5160.32
544_W564_F0.5160.32
106_S177_A0.5150.32
513_F579_P0.5140.32
389_G426_G0.5140.32
516_K550_K0.5130.32
328_A407_A0.5120.32
443_F446_V0.5120.32
509_V562_V0.5120.32
251_V254_L0.5120.32
544_W547_A0.5120.32
454_P458_E0.5120.32
212_T293_F0.5120.32
83_S288_L0.5110.32
173_Y412_I0.5110.32
541_E572_A0.5110.32
333_A336_S0.5110.32
141_V144_I0.5100.32
544_W588_Y0.5100.32
216_I322_L0.5090.32
460_S525_Q0.5080.32
519_I531_I0.5080.32
505_V555_V0.5080.32
116_I305_F0.5070.31
515_T562_V0.5070.31
79_H229_W0.5070.31
162_M220_I0.5060.31
230_I254_L0.5060.31
575_D579_P0.5060.31
356_S372_N0.5060.31
84_D570_K0.5050.31
223_A329_N0.5050.31
454_P554_K0.5050.31
144_I311_N0.5040.31
14_V48_L0.5040.31
500_E546_T0.5030.31
497_E590_F0.5030.31
129_A159_L0.5030.31
469_K571_A0.5030.31
258_T457_H0.5030.31
498_E590_F0.5030.31
425_I430_A0.5020.31
11_L49_P0.5020.31
578_T602_K0.5020.31
330_M334_G0.5020.31
114_P303_Y0.5010.31
303_Y306_V0.5010.31
531_I578_T0.5000.31
303_Y312_N0.5000.31
502_V557_P0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gprA 1 0.2529 100 0.759 Contact Map
1f3zA 2 0.243 100 0.76 Contact Map
3ourB 1 0.243 100 0.762 Contact Map
3qnqA 2 0.619 100 0.764 Contact Map
1ax3A 1 0.2627 100 0.766 Contact Map
3ipjA 1 0.1494 100 0.872 Contact Map
1ibaA 1 0.1264 100 0.88 Contact Map
3bp3A 1 0.133 100 0.881 Contact Map
2d5dA 1 0.1149 98.7 0.953 Contact Map
1dczA 1 0.1264 98.6 0.954 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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