GREMLIN Database
NAGZ - Beta-hexosaminidase
UniProt: P40406 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 642 (539)
Sequences: 6185 (4249)
Seq/√Len: 183.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
432_E601_M4.2891.00
149_S433_K4.1481.00
154_Y209_K4.1121.00
429_K433_K4.0891.00
155_Q429_K3.8211.00
36_N387_E3.7351.00
220_L263_A3.5061.00
159_I426_A3.3911.00
45_D369_K3.3851.00
490_N606_Q3.2561.00
146_A614_P3.2181.00
248_R308_E3.2051.00
432_E607_A3.0001.00
256_Q260_D2.9141.00
608_K635_N2.8521.00
303_G307_Q2.8011.00
298_K303_G2.7681.00
340_K381_Q2.7321.00
37_Q41_R2.6941.00
559_L574_A2.5881.00
177_V204_G2.5021.00
48_L369_K2.4601.00
487_S604_F2.3981.00
156_T430_L2.3951.00
602_A607_A2.3811.00
306_R384_N2.3581.00
51_M382_I2.3421.00
201_S257_K2.3361.00
435_V602_A2.3171.00
243_G246_R2.3091.00
572_E628_Y2.2981.00
150_R202_R2.2881.00
314_V392_L2.2421.00
244_Q248_R2.2421.00
51_M339_V2.2381.00
298_K302_T2.2291.00
344_D388_R2.2241.00
369_K373_K2.2231.00
370_E374_N2.1631.00
299_K303_G2.1561.00
79_S83_K2.1491.00
264_D395_K2.1391.00
219_A265_M2.1241.00
217_A264_D2.1181.00
491_F604_F2.1071.00
496_F499_E2.1011.00
483_P520_D2.0931.00
381_Q384_N2.0681.00
551_L575_K2.0581.00
428_K601_M2.0261.00
45_D373_K2.0041.00
431_A598_A1.9961.00
428_K432_E1.9821.00
421_K425_K1.9731.00
601_M606_Q1.9481.00
268_T295_T1.9461.00
441_E575_K1.9401.00
143_A434_A1.9301.00
428_K597_P1.8881.00
492_A495_V1.8581.00
379_E383_N1.8491.00
336_V371_A1.8371.00
154_Y158_S1.8251.00
560_M580_V1.8091.00
202_R205_L1.8031.00
549_A552_Q1.7931.00
629_P632_Y1.7901.00
484_V488_K1.7871.00
332_E370_E1.7681.00
153_A203_L1.7561.00
584_K595_N1.7541.00
138_F159_I1.7451.00
594_P597_P1.7451.00
259_I266_V1.7321.00
368_L377_I1.7201.00
489_M597_P1.7161.00
51_M389_I1.7001.00
217_A392_L1.6871.00
519_N547_M1.6741.00
144_L153_A1.6621.00
330_G333_E1.6521.00
44_L372_V1.6481.00
424_L594_P1.6421.00
225_G242_H1.6401.00
195_S616_D1.6371.00
212_Q218_S1.6361.00
155_Q158_S1.6361.00
521_P547_M1.6201.00
436_T581_Y1.6141.00
486_L600_V1.6131.00
447_F516_V1.6101.00
188_I615_V1.5831.00
154_Y206_Y1.5831.00
299_K304_L1.5811.00
495_V498_T1.5741.00
46_E113_S1.5621.00
336_V340_K1.5531.00
332_E374_N1.5521.00
136_T427_E1.5391.00
208_M258_A1.5321.00
548_K570_N1.5321.00
174_S211_L1.5221.00
159_I423_H1.5211.00
34_D394_I1.5201.00
519_N550_A1.5151.00
378_P381_Q1.5091.00
44_L382_I1.5091.00
147_A430_L1.5061.00
496_F500_H1.4961.00
35_A387_E1.4941.00
580_V584_K1.4931.00
107_D111_K1.4921.00
202_R257_K1.4901.00
495_V500_H1.4871.00
163_E423_H1.4851.00
245_E249_E1.4831.00
220_L258_A1.4821.00
150_R203_L1.4821.00
504_V508_D1.4811.00
301_M315_I1.4791.00
317_T343_V1.4681.00
220_L266_V1.4631.00
157_G207_T1.4601.00
256_Q309_M1.4581.00
542_F545_A1.4551.00
154_Y213_R1.4531.00
145_G614_P1.4341.00
497_K500_H1.4321.00
458_V519_N1.4301.00
419_G424_L1.4261.00
157_G211_L1.4261.00
544_R548_K1.4231.00
420_S423_H1.4111.00
509_Y512_T1.4101.00
561_S579_A1.4081.00
295_T321_N1.4071.00
53_M88_G1.4031.00
340_K378_P1.4001.00
417_I420_S1.3971.00
469_E472_I1.3931.00
144_L156_T1.3871.00
517_V555_K1.3851.00
495_V499_E1.3841.00
383_N386_V1.3831.00
259_I263_A1.3751.00
550_A557_F1.3721.00
578_I603_I1.3701.00
35_A39_V1.3661.00
292_V297_S1.3591.00
107_D110_Q1.3581.00
545_A548_K1.3581.00
205_L209_K1.3561.00
455_I516_V1.3561.00
302_T307_Q1.3531.00
380_Q383_N1.3511.00
151_I155_Q1.3441.00
369_K372_V1.3331.00
336_V376_D1.3331.00
35_A391_S1.3321.00
268_T301_M1.3311.00
171_T265_M1.3281.00
294_A297_S1.3281.00
487_S603_I1.3161.00
268_T343_V1.3151.00
154_Y210_G1.3131.00
205_L257_K1.3081.00
152_N430_L1.3021.00
158_S162_K1.3021.00
367_A370_E1.2931.00
171_T316_V1.2931.00
305_L315_I1.2881.00
455_I491_F1.2841.00
268_T321_N1.2821.00
106_T110_Q1.2791.00
48_L382_I1.2791.00
179_I250_V1.2771.00
444_T575_K1.2751.00
150_R206_Y1.2731.00
481_I597_P1.2701.00
454_R513_G1.2701.00
43_S113_S1.2641.00
483_P599_G1.2641.00
517_V550_A1.2631.00
253_Y257_K1.2621.00
429_K432_E1.2551.00
448_K452_G1.2491.00
217_A396_R1.2461.00
372_V382_I1.2451.00
602_A609_P1.2441.00
158_S213_R1.2431.00
152_N426_A1.2411.00
345_I389_I1.2411.00
314_V345_I1.2361.00
259_I309_M1.2361.00
103_V107_D1.2321.00
439_K628_Y1.2311.00
505_K509_Y1.2301.00
547_M571_F1.2291.00
572_E577_L1.2291.00
340_K377_I1.2241.00
559_L577_L1.2221.00
370_E373_K1.2211.00
463_E484_V1.2181.00
36_N39_V1.2161.00
147_A203_L1.2091.00
47_K383_N1.2091.00
39_V386_V1.2001.00
503_Q506_E1.2001.00
561_S568_A1.1991.00
485_S488_K1.1961.00
183_P624_G1.1951.00
394_I399_Y1.1941.00
545_A549_A1.1911.00
519_N522_V1.1851.00
487_S491_F1.1811.00
559_L571_F1.1811.00
265_M392_L1.1791.00
494_Q499_E1.1771.00
259_I311_F1.1761.00
312_N395_K1.1751.00
485_S489_M1.1711.00
34_D37_Q1.1701.00
551_L574_A1.1691.00
266_V305_L1.1611.00
179_I200_T1.1501.00
44_L379_E1.1391.00
521_P559_L1.1381.00
198_E202_R1.1381.00
440_N576_A1.1351.00
444_T576_A1.1341.00
39_V387_E1.1331.00
104_Q108_D1.1311.00
100_K104_Q1.1291.00
224_P300_V1.1271.00
172_D216_I1.1251.00
177_V258_A1.1161.00
155_Q426_A1.1101.00
340_K376_D1.1101.00
371_A376_D1.1071.00
507_A511_I1.1031.00
490_N601_M1.0971.00
435_V580_V1.0961.00
333_E337_M1.0961.00
515_Y518_K1.0941.00
269_A294_A1.0901.00
597_P601_M1.0881.00
580_V599_G1.0861.00
517_V520_D1.0841.00
372_V378_P1.0801.00
148_R199_L1.0781.00
258_A263_A1.0731.00
518_K522_V1.0711.00
391_S395_K1.0641.00
42_M114_P1.0611.00
551_L557_F1.0611.00
457_I487_S1.0611.00
46_E85_Q1.0611.00
144_L430_L1.0601.00
108_D111_K1.0591.00
373_K379_E1.0591.00
527_V530_D1.0591.00
553_H556_P1.0531.00
339_V385_S1.0511.00
140_G190_V1.0391.00
482_K485_S1.0321.00
211_L218_S1.0301.00
337_M340_K1.0291.00
165_S216_I1.0251.00
160_I211_L1.0241.00
339_V368_L1.0231.00
541_V545_A1.0211.00
508_D549_A1.0180.99
509_Y513_G1.0130.99
98_T101_Q1.0130.99
486_L490_N1.0090.99
332_E376_D1.0050.99
43_S46_E1.0010.99
206_Y209_K1.0010.99
224_P252_L1.0010.99
453_S516_V1.0000.99
510_I514_S0.9970.99
103_V106_T0.9930.99
425_K429_K0.9920.99
265_M314_V0.9920.99
456_L514_S0.9910.99
490_N604_F0.9910.99
244_Q299_K0.9860.99
516_V558_V0.9810.99
201_S205_L0.9790.99
428_K594_P0.9780.99
252_L304_L0.9750.99
492_A496_F0.9740.99
481_I486_L0.9740.99
544_R571_F0.9730.99
38_I41_R0.9730.99
101_Q104_Q0.9720.99
53_M173_F0.9720.99
205_L261_A0.9720.99
501_E504_V0.9710.99
433_K610_K0.9700.99
257_K260_D0.9680.99
578_I609_P0.9640.99
562_L580_V0.9640.99
491_F494_Q0.9610.99
217_A314_V0.9600.99
177_V220_L0.9590.99
428_K598_A0.9570.99
444_T516_V0.9560.99
197_R201_S0.9500.99
302_T341_A0.9490.99
218_S263_A0.9490.99
437_V578_I0.9480.99
501_E505_K0.9450.99
153_A430_L0.9430.99
442_Q575_K0.9360.99
223_F252_L0.9360.99
149_S429_K0.9340.99
601_M607_A0.9320.99
317_T322_M0.9300.99
501_E545_A0.9280.99
492_A499_E0.9280.99
506_E510_I0.9270.99
266_V311_F0.9250.99
158_S214_Q0.9250.99
34_D400_P0.9240.99
116_I390_I0.9200.99
366_Q370_E0.9200.99
37_Q40_N0.9190.99
569_A627_L0.9160.99
494_Q497_K0.9160.99
417_I423_H0.9140.99
212_Q264_D0.9140.99
457_I484_V0.9130.99
560_M599_G0.9120.99
49_G85_Q0.9120.99
124_Q172_D0.9090.99
296_L325_I0.9070.99
508_D512_T0.9060.99
35_A394_I0.9050.99
151_I154_Y0.9040.99
518_K560_M0.9040.99
103_V110_Q0.8950.99
506_E509_Y0.8940.99
538_W567_D0.8900.99
209_K261_A0.8900.99
156_T426_A0.8880.99
338_A343_V0.8880.99
161_G214_Q0.8840.99
494_Q498_T0.8820.99
508_D553_H0.8780.98
432_E598_A0.8770.98
386_V390_I0.8720.98
201_S253_Y0.8710.98
504_V549_A0.8700.98
172_D211_L0.8700.98
136_T163_E0.8650.98
619_S627_L0.8640.98
244_Q308_E0.8600.98
487_S518_K0.8590.98
344_D385_S0.8560.98
470_Q473_H0.8550.98
319_A347_L0.8520.98
162_K423_H0.8510.98
554_N557_F0.8500.98
491_F497_K0.8500.98
454_R496_F0.8490.98
138_F156_T0.8480.98
333_E376_D0.8440.98
206_Y210_G0.8440.98
456_L510_I0.8440.98
166_A417_I0.8430.98
504_V542_F0.8430.98
365_I369_K0.8430.98
526_G530_D0.8410.98
146_A436_T0.8390.98
517_V557_F0.8350.98
571_F577_L0.8330.98
104_Q107_D0.8310.98
257_K261_A0.8300.98
248_R304_L0.8290.98
413_K416_K0.8280.98
180_N192_S0.8260.98
302_T384_N0.8190.98
147_A434_A0.8190.98
454_R515_Y0.8180.98
148_R630_L0.8170.98
145_G192_S0.8160.98
246_R250_V0.8120.97
157_G208_M0.8110.97
193_F203_L0.8110.97
164_L172_D0.8110.97
623_P626_T0.8100.97
80_L83_K0.8100.97
381_Q385_S0.8090.97
194_S200_T0.8080.97
569_A619_S0.8080.97
149_S152_N0.8050.97
577_L628_Y0.8050.97
385_S388_R0.8040.97
121_S171_T0.8020.97
153_A207_T0.8010.97
105_L110_Q0.8000.97
537_K567_D0.7970.97
608_K637_K0.7970.97
492_A497_K0.7970.97
635_N639_G0.7970.97
427_E431_A0.7960.97
301_M343_V0.7960.97
447_F558_V0.7950.97
456_L517_V0.7940.97
422_Q425_K0.7890.97
102_T109_Y0.7880.97
128_I167_L0.7860.97
273_F294_A0.7840.97
211_L216_I0.7840.97
384_N388_R0.7830.97
45_D48_L0.7830.97
339_V382_I0.7820.97
119_M170_N0.7820.97
273_F286_D0.7800.97
384_N387_E0.7790.97
425_K432_E0.7770.97
567_D621_T0.7730.97
520_D523_V0.7720.97
377_I381_Q0.7710.97
253_Y256_Q0.7710.97
245_E286_D0.7710.97
101_Q105_L0.7690.97
371_A374_N0.7690.97
207_T211_L0.7680.97
372_V377_I0.7680.97
312_N391_S0.7670.96
301_M306_R0.7670.96
556_P575_K0.7670.96
521_P561_S0.7650.96
437_V609_P0.7650.96
41_R114_P0.7650.96
463_E485_S0.7640.96
403_N406_S0.7610.96
516_V556_P0.7600.96
426_A429_K0.7600.96
548_K552_Q0.7580.96
491_F495_V0.7570.96
448_K453_S0.7540.96
486_L489_M0.7540.96
294_A300_V0.7510.96
458_V550_A0.7510.96
145_G194_S0.7470.96
78_A82_K0.7450.96
483_P562_L0.7450.96
107_D404_S0.7440.96
106_T109_Y0.7440.96
452_G604_F0.7440.96
48_L368_L0.7410.96
242_H246_R0.7400.96
292_V296_L0.7390.96
544_R570_N0.7390.96
224_P309_M0.7380.96
43_S114_P0.7380.96
102_T110_Q0.7370.96
455_I604_F0.7370.96
224_P294_A0.7350.96
178_D227_G0.7340.95
208_M212_Q0.7340.95
535_S620_V0.7330.95
520_D599_G0.7320.95
208_M218_S0.7320.95
572_E627_L0.7300.95
444_T558_V0.7280.95
304_L308_E0.7270.95
331_Q351_S0.7270.95
226_H269_A0.7260.95
504_V507_A0.7250.95
518_K523_V0.7240.95
448_K451_K0.7240.95
296_L337_M0.7220.95
220_L259_I0.7210.95
166_A418_V0.7200.95
439_K577_L0.7190.95
241_S246_R0.7180.95
435_V578_I0.7180.95
578_I602_A0.7160.95
151_I206_Y0.7160.95
332_E371_A0.7150.95
325_I338_A0.7140.95
34_D41_R0.7120.95
208_M263_A0.7120.95
152_N429_K0.7070.94
103_V404_S0.7050.94
306_R388_R0.7050.94
199_L630_L0.7050.94
302_T306_R0.7030.94
375_G378_P0.7010.94
159_I430_L0.6980.94
511_I514_S0.6980.94
326_A334_A0.6980.94
607_A610_K0.6980.94
616_D626_T0.6980.94
435_V584_K0.6980.94
53_M90_I0.6970.94
458_V517_V0.6970.94
143_A581_Y0.6940.94
87_G91_L0.6930.94
491_F496_F0.6900.94
264_D392_L0.6900.94
196_N630_L0.6900.94
372_V379_E0.6890.94
508_D550_A0.6890.94
538_W544_R0.6880.94
540_T543_P0.6860.94
121_S173_F0.6860.94
247_L300_V0.6820.93
87_G90_I0.6810.93
176_V192_S0.6810.93
248_R256_Q0.6800.93
97_K102_T0.6800.93
613_L617_I0.6800.93
525_D528_I0.6800.93
517_V553_H0.6790.93
139_P430_L0.6790.93
298_K340_K0.6780.93
88_G92_F0.6770.93
333_E336_V0.6760.93
439_K632_Y0.6750.93
268_T317_T0.6740.93
314_V389_I0.6730.93
486_L596_I0.6730.93
507_A510_I0.6720.93
226_H229_T0.6720.93
319_A348_M0.6720.93
401_A404_S0.6720.93
50_Q393_K0.6710.93
560_M578_I0.6700.93
479_K483_P0.6690.93
520_D562_L0.6670.93
326_A331_Q0.6670.93
87_G92_F0.6670.93
138_F426_A0.6670.93
34_D38_I0.6660.93
596_I600_V0.6640.92
525_D529_D0.6640.92
339_V346_A0.6630.92
152_N155_Q0.6630.92
154_Y214_Q0.6620.92
199_L203_L0.6620.92
567_D570_N0.6600.92
441_E444_T0.6590.92
100_K103_V0.6590.92
555_K575_K0.6570.92
235_Y324_A0.6570.92
225_G240_V0.6570.92
501_E542_F0.6560.92
507_A546_V0.6560.92
458_V546_V0.6550.92
432_E597_P0.6550.92
217_A265_M0.6540.92
161_G211_L0.6540.92
463_E482_K0.6520.92
88_G347_L0.6520.92
193_F200_T0.6520.92
123_D347_L0.6510.92
574_A577_L0.6510.92
190_V471_T0.6500.92
102_T106_T0.6500.92
452_G455_I0.6470.91
461_Y562_L0.6450.91
568_A571_F0.6440.91
628_Y632_Y0.6410.91
145_G193_F0.6410.91
394_I400_P0.6400.91
145_G199_L0.6390.91
602_A610_K0.6370.91
385_S389_I0.6360.91
295_T343_V0.6350.91
454_R498_T0.6350.91
608_K636_I0.6350.91
252_L309_M0.6330.91
306_R391_S0.6320.90
181_N251_E0.6290.90
138_F427_E0.6290.90
508_D517_V0.6280.90
619_S623_P0.6270.90
510_I513_G0.6260.90
520_D560_M0.6260.90
194_S199_L0.6260.90
538_W621_T0.6250.90
126_G140_G0.6250.90
488_K492_A0.6240.90
517_V521_P0.6230.90
131_R134_E0.6220.90
608_K639_G0.6200.90
52_L348_M0.6200.90
503_Q507_A0.6190.90
467_S472_I0.6190.90
487_S494_Q0.6190.90
468_I595_N0.6190.90
518_K558_V0.6180.89
547_M551_L0.6180.89
109_Y118_L0.6170.89
375_G379_E0.6160.89
117_P398_M0.6160.89
372_V375_G0.6160.89
224_P247_L0.6150.89
173_F316_V0.6150.89
180_N188_I0.6140.89
387_E391_S0.6120.89
457_I462_E0.6100.89
123_D319_A0.6090.89
88_G91_L0.6090.89
122_I169_I0.6080.89
156_T207_T0.6070.89
524_N527_V0.6070.89
467_S471_T0.6070.89
234_H237_L0.6070.89
39_V390_I0.6060.89
454_R514_S0.6040.88
393_K398_M0.6040.88
45_D85_Q0.6040.88
494_Q500_H0.6040.88
536_S621_T0.6030.88
519_N557_F0.6020.88
608_K612_T0.6010.88
505_K508_D0.6010.88
90_I319_A0.6000.88
49_G81_V0.6000.88
102_T105_L0.5970.88
121_S345_I0.5960.88
425_K428_K0.5950.88
491_F499_E0.5940.88
93_A97_K0.5940.88
382_I386_V0.5930.87
424_L428_K0.5930.87
156_T159_I0.5920.87
248_R252_L0.5910.87
505_K549_A0.5910.87
437_V636_I0.5910.87
518_K603_I0.5900.87
390_I393_K0.5900.87
464_Q467_S0.5890.87
98_T106_T0.5890.87
228_D251_E0.5880.87
458_V507_A0.5870.87
105_L109_Y0.5870.87
224_P304_L0.5860.87
101_Q110_Q0.5860.87
300_V304_L0.5850.87
460_P543_P0.5840.87
48_L372_V0.5840.87
156_T160_I0.5840.87
525_D530_D0.5840.87
621_T624_G0.5830.87
481_I596_I0.5830.87
546_V550_A0.5830.87
335_V367_A0.5830.87
162_K420_S0.5820.87
153_A157_G0.5810.86
549_A553_H0.5810.86
322_M346_A0.5810.86
100_K415_K0.5800.86
39_V383_N0.5780.86
307_Q310_G0.5760.86
367_A371_A0.5760.86
230_D241_S0.5760.86
243_G286_D0.5760.86
570_N574_A0.5760.86
332_E367_A0.5750.86
270_H321_N0.5750.86
78_A108_D0.5740.86
490_N597_P0.5730.86
91_L106_T0.5730.86
570_N573_E0.5730.86
225_G247_L0.5720.86
179_I254_P0.5710.85
106_T120_L0.5710.85
163_E419_G0.5710.85
38_I394_I0.5700.85
244_Q286_D0.5700.85
344_D381_Q0.5700.85
401_A405_D0.5690.85
498_T514_S0.5680.85
303_G308_E0.5660.85
124_Q164_L0.5660.85
317_T321_N0.5660.85
121_S347_L0.5650.85
36_N41_R0.5650.85
36_N40_N0.5650.85
458_V511_I0.5640.85
44_L373_K0.5640.85
337_M341_A0.5610.84
53_M171_T0.5600.84
380_Q384_N0.5600.84
173_F319_A0.5590.84
514_S517_V0.5570.84
397_G400_P0.5560.84
339_V372_V0.5560.84
46_E112_A0.5540.84
148_R612_T0.5540.84
179_I251_E0.5530.84
54_P86_F0.5530.84
622_K625_N0.5530.84
320_L323_K0.5520.84
244_Q304_L0.5520.84
392_L395_K0.5510.83
124_Q160_I0.5500.83
402_R405_D0.5490.83
304_L309_M0.5490.83
142_M581_Y0.5480.83
452_G516_V0.5480.83
34_D399_Y0.5480.83
547_M574_A0.5480.83
209_K262_G0.5480.83
598_A602_A0.5480.83
52_L364_V0.5470.83
80_L85_Q0.5460.83
463_E488_K0.5460.83
123_D472_I0.5450.83
492_A500_H0.5450.83
499_E510_I0.5440.83
386_V389_I0.5430.83
195_S630_L0.5430.83
99_T103_V0.5430.83
483_P487_S0.5420.82
330_G374_N0.5420.82
322_M343_V0.5410.82
81_V86_F0.5400.82
539_A543_P0.5400.82
579_A617_I0.5390.82
173_F347_L0.5390.82
447_F603_I0.5380.82
98_T102_T0.5360.82
399_Y402_R0.5350.82
148_R614_P0.5350.82
512_T553_H0.5350.82
242_H247_L0.5350.82
500_H506_E0.5340.81
518_K521_P0.5330.81
402_R406_S0.5330.81
379_E382_I0.5310.81
147_A611_G0.5310.81
155_Q422_Q0.5300.81
490_N493_S0.5290.81
620_V623_P0.5280.81
152_N433_K0.5280.81
507_A514_S0.5270.81
79_S82_K0.5270.81
164_L169_I0.5270.81
218_S264_D0.5260.81
616_D624_G0.5250.80
104_Q110_Q0.5240.80
515_Y522_V0.5210.80
399_Y403_N0.5200.80
487_S490_N0.5200.80
466_A469_E0.5200.80
162_K214_Q0.5180.80
84_Y88_G0.5180.80
454_R495_V0.5180.80
157_G161_G0.5170.79
455_I496_F0.5170.79
146_A262_G0.5160.79
209_K214_Q0.5160.79
223_F305_L0.5160.79
229_T251_E0.5160.79
170_N396_R0.5150.79
146_A581_Y0.5150.79
487_S600_V0.5150.79
128_I164_L0.5150.79
419_G423_H0.5140.79
302_T381_Q0.5130.79
403_N407_T0.5130.79
568_A617_I0.5130.79
561_S617_I0.5120.79
312_N373_K0.5120.79
180_N615_V0.5120.79
364_V377_I0.5110.79
208_M220_L0.5110.79
165_S170_N0.5110.79
472_I476_I0.5110.79
141_N176_V0.5110.79
492_A498_T0.5100.78
508_D511_I0.5100.78
522_V525_D0.5100.78
418_V423_H0.5100.78
602_A608_K0.5090.78
519_N523_V0.5090.78
435_V599_G0.5080.78
373_K376_D0.5080.78
486_L597_P0.5080.78
145_G200_T0.5070.78
107_D403_N0.5070.78
53_M347_L0.5070.78
55_D348_M0.5060.78
330_G334_A0.5050.78
89_I109_Y0.5050.78
138_F423_H0.5050.78
523_V527_V0.5050.78
471_T474_D0.5040.78
91_L97_K0.5040.78
173_F270_H0.5040.78
461_Y467_S0.5040.78
39_V42_M0.5040.78
541_V544_R0.5030.78
118_L170_N0.5030.78
142_M194_S0.5030.78
101_Q108_D0.5020.77
348_M351_S0.5020.77
49_G86_F0.5010.77
488_K497_K0.5000.77
513_G517_V0.5000.77
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bmxA 1 0.933 100 0.183 Contact Map
3u48A 2 0.8598 100 0.213 Contact Map
3wliA 1 0.8692 100 0.213 Contact Map
3rrxA 1 0.8738 100 0.223 Contact Map
4i3gA 1 0.8022 100 0.234 Contact Map
3abzA 3 0.7882 100 0.254 Contact Map
2x41A 1 0.8053 100 0.255 Contact Map
3zyzA 1 0.8162 100 0.263 Contact Map
4iibA 2 0.8536 100 0.269 Contact Map
4d0jA 4 0.8349 100 0.269 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0149 seconds.