GREMLIN Database
YTXJ - Uncharacterized protein YtxJ
UniProt: P39914 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 108 (103)
Sequences: 479 (387)
Seq/√Len: 38.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
82_F89_V4.4001.00
89_V92_H3.8941.00
67_F71_T3.7451.00
30_T59_Q3.6771.00
20_G52_P3.1521.00
56_L68_I2.5811.00
23_V83_I2.1260.99
38_F42_D2.0860.99
12_F24_F2.0480.99
18_Q52_P2.0110.99
22_F52_P1.9360.98
64_L68_I1.7360.97
9_E64_L1.6620.96
5_L55_Y1.6490.96
29_T57_Q1.6430.95
38_F55_Y1.6400.95
9_E67_F1.6070.95
9_E63_P1.5680.94
21_V85_Q1.5600.94
74_V92_H1.5450.94
102_A105_Q1.5180.93
12_F71_T1.5100.93
4_Q52_P1.4890.92
58_V61_A1.4650.92
11_E14_R1.3800.89
7_Q11_E1.3730.89
57_Q61_A1.3370.88
13_K71_T1.3260.87
32_P40_E1.3200.87
25_L38_F1.3080.86
23_V51_V1.2960.86
16_A72_Y1.2890.86
56_L59_Q1.2850.85
41_F53_A1.2480.84
93_T97_Q1.2280.83
25_L29_T1.2140.82
56_L64_L1.2090.82
27_H57_Q1.2060.81
72_Y87_G1.2040.81
5_L57_Q1.2030.81
81_I103_I1.2030.81
15_I24_F1.2010.81
16_A71_T1.1990.81
15_I22_F1.1680.79
45_A99_T1.1320.77
30_T75_K1.1040.75
47_Q100_E1.0720.73
85_Q90_K1.0680.73
68_I83_I1.0580.72
83_I102_A1.0570.72
3_K38_F1.0470.71
43_A100_E1.0390.71
46_N104_E1.0350.70
15_I54_Y1.0110.69
9_E13_K1.0030.68
32_P37_A0.9890.67
29_T59_Q0.9850.67
11_E85_Q0.9580.64
58_V91_W0.9500.64
74_V77_E0.9480.64
11_E18_Q0.9260.62
81_I93_T0.9180.61
57_Q60_E0.9150.61
29_T64_L0.8940.59
8_S64_L0.8780.58
37_A91_W0.8740.57
60_E73_G0.8520.55
38_F58_V0.8370.54
91_W99_T0.8000.51
52_P59_Q0.7930.50
81_I105_Q0.7780.49
35_Q45_A0.7770.49
52_P105_Q0.7750.48
40_E103_I0.7640.47
25_L41_F0.7520.46
12_F58_V0.7480.46
28_S94_S0.7400.45
5_L81_I0.7320.45
49_E104_E0.7290.44
19_E70_E0.7280.44
53_A72_Y0.7250.44
78_S98_I0.7220.44
36_A96_S0.7210.44
12_F56_L0.7100.43
11_E15_I0.7080.42
32_P45_A0.6980.42
37_A83_I0.6960.41
69_A93_T0.6940.41
7_Q35_Q0.6930.41
32_P35_Q0.6920.41
81_I102_A0.6860.41
23_V81_I0.6810.40
73_G105_Q0.6690.39
91_W96_S0.6620.38
71_T86_N0.6550.38
22_F84_I0.6510.38
30_T77_E0.6480.37
4_Q100_E0.6470.37
3_K57_Q0.6460.37
73_G88_E0.6360.36
6_I22_F0.6360.36
50_D81_I0.6350.36
44_F58_V0.6320.36
28_S34_S0.6310.36
49_E82_F0.6250.35
33_I103_I0.6200.35
39_H97_Q0.6170.35
21_V84_I0.6100.34
11_E45_A0.6070.34
14_R18_Q0.6030.34
30_T60_E0.6010.33
21_V83_I0.5990.33
40_E58_V0.5980.33
101_A104_E0.5950.33
22_F38_F0.5930.33
67_F70_E0.5820.32
14_R88_E0.5800.32
29_T66_N0.5770.32
70_E75_K0.5750.31
56_L66_N0.5690.31
17_E86_N0.5690.31
42_D63_P0.5660.31
20_G49_E0.5660.31
59_Q64_L0.5650.31
5_L49_E0.5610.30
30_T33_I0.5600.30
9_E47_Q0.5590.30
12_F29_T0.5570.30
10_E52_P0.5550.30
50_D93_T0.5510.30
44_F83_I0.5500.30
14_R51_V0.5480.29
47_Q63_P0.5470.29
93_T105_Q0.5460.29
41_F84_I0.5440.29
8_S90_K0.5410.29
27_H94_S0.5410.29
11_E88_E0.5380.29
21_V50_D0.5350.28
75_K91_W0.5260.28
28_S62_R0.5200.27
82_F90_K0.5180.27
56_L61_A0.5180.27
4_Q86_N0.5160.27
16_A87_G0.5160.27
53_A74_V0.5120.27
15_I98_I0.5100.27
41_F81_I0.5080.26
30_T96_S0.5080.26
32_P92_H0.5050.26
72_Y84_I0.5030.26
9_E105_Q0.5020.26
3_K36_A0.5020.26
25_L84_I0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3iv4A 1 0.9907 99.5 0.66 Contact Map
4cw9A 2 0.9259 98.7 0.765 Contact Map
1gh2A 1 0.9352 98.6 0.768 Contact Map
2j23A 1 0.9352 98.6 0.772 Contact Map
4euyA 1 0.7685 98.6 0.773 Contact Map
1r26A 1 0.9352 98.6 0.773 Contact Map
2wz9A 1 0.9352 98.5 0.777 Contact Map
1xflA 1 0.9352 98.5 0.779 Contact Map
1ep7A 1 0.9352 98.5 0.78 Contact Map
4i8bA 2 0.9259 98.5 0.78 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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