YUXL - BACSU - GREMLIN Contacts

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YUXL - Uncharacterized peptidase YuxL

UniProt:	P39839	Sequences: MKKLITADDITAIVSVTDPQYAPDGTRAAYVKSQVNQEKDSYTSNIWIYETKTGGSVPWTHGEKRSTDPRWSPDGRTLAFISDREGDAAQLYIMSTEGGEARKLTDIPYGVSKPLWSPDGESILVTVSLGEGESIDDREKTEQDSYEPVEVQGLSYKRDGKGLTRGAYAQLVLVSVKSGEMKELTSHKADHGDPAFSPDGKWLVFSANLTETDDASKPHDVYIMSLESGDLKQVTPHRGSFGSSSFSPDGRYLALLGNEKEYKNATLSKAWLYDIEQGRLTCLTEMLDVHLADALIGDSLIGGAEQRPIWTKDSQGFYVIGTDQGSTGIYYISIEGLVYPIRLEKEYINSFSLSPDEQHFIASVTKPDRPSELYSIPLGQEEKQLTGANDKFVREHTISIPEEIQYATEDGVMVNGWLMRPAQMEGETTYPLILNIHGGPHMMYGHTYFHEFQVLAAKGYAVVYINPRGSHGYGQEFVNAVRGDYGGKDYDDVMQAVDEAIKRDPHIDPKRLGVTGGSYGGFMTNWIVGQTNRFKAAVTQRSISNWISFHGVSDIGYFFTDWQLEHDMFEDTEKLWDRSPLKYAANVETPLLILHGERDDRCPIEQAEQLFIALKKMGKETKLVRFPNASHNLSRTGHPRQRIKRLNYISSWFDQHL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	657 (598)
Sequences:	1189 (1017)
Seq/√Len:	41.6

ECOLI - PTRB
BACSU - YUXL
HALSA - Q9HN07 Q9HS46
SULSO - Q97VD6 Q7LX61 Q97YB2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
407_A	413_M	4.473	1.00
29_A	46_I	4.275	1.00
225_S	228_S	4.207	1.00
626_F	644_K	4.073	1.00
528_V	537_A	3.875	1.00
498_D	533_R	3.696	1.00
402_E	420_R	3.640	1.00
587_V	610_L	3.571	1.00
405_Q	413_M	3.522	1.00
274_D	277_Q	3.465	1.00
514_V	527_I	3.454	1.00
499_E	502_K	3.322	1.00
424_M	506_H	3.215	1.00
316_G	331_Y	3.186	1.00
644_K	648_Y	2.978	1.00
513_G	653_F	2.969	1.00
532_N	588_E	2.871	1.00
484_D	487_G	2.845	1.00
366_K	369_R	2.828	1.00
406_Y	496_A	2.794	1.00
424_M	430_Y	2.637	1.00
418_L	463_V	2.623	1.00
416_G	496_A	2.614	1.00
103_K	106_D	2.519	1.00
508_D	511_R	2.464	1.00
430_Y	461_A	2.454	1.00
425_E	428_T	2.415	1.00
95_S	98_G	2.415	1.00
181_M	184_L	2.412	1.00
460_Y	654_D	2.409	1.00
331_Y	339_Y	2.383	1.00
629_A	641_Q	2.381	1.00
409_E	495_Q	2.379	1.00
204_V	246_F	2.352	1.00
463_V	496_A	2.348	1.00
458_K	654_D	2.348	1.00
622_K	655_Q	2.334	1.00
591_L	619_K	2.326	1.00
432_L	507_I	2.302	1.00
485_Y	546_W	2.300	1.00
468_R	492_D	2.297	1.00
26_T	52_K	2.294	1.00
289_V	323_D	2.271	1.00
490_Y	527_I	2.256	1.00
418_L	461_A	2.224	1.00
399_S	453_Q	2.183	1.00
434_L	493_V	2.183	1.00
197_S	200_G	2.177	1.00
517_G	541_R	2.175	1.00
517_G	540_Q	2.156	0.99
98_G	101_A	2.155	0.99
21_Y	28_A	2.123	0.99
433_I	653_F	2.092	0.99
18_D	70_R	2.087	0.99
29_A	78_L	2.078	0.99
504_D	507_I	2.071	0.99
406_Y	416_G	2.061	0.99
160_G	163_L	2.046	0.99
463_V	500_A	2.035	0.99
436_I	514_V	2.028	0.99
20_Q	70_R	1.972	0.99
23_P	75_G	1.960	0.99
175_S	178_S	1.953	0.99
94_M	98_G	1.948	0.99
148_P	157_K	1.948	0.99
416_G	463_V	1.939	0.99
490_Y	494_M	1.939	0.99
90_Q	105_T	1.921	0.99
248_P	310_W	1.913	0.99
90_Q	98_G	1.911	0.99
73_P	116_W	1.910	0.99
91_L	94_M	1.909	0.99
524_T	537_A	1.899	0.99
311_T	318_Y	1.872	0.98
499_E	503_R	1.864	0.98
418_L	506_H	1.858	0.98
150_E	153_G	1.851	0.98
90_Q	94_M	1.845	0.98
205_F	208_N	1.830	0.98
148_P	158_R	1.828	0.98
432_L	463_V	1.808	0.98
27_R	50_E	1.803	0.98
461_A	506_H	1.791	0.98
104_L	107_I	1.762	0.98
29_A	69_P	1.753	0.98
525_N	539_T	1.752	0.98
604_I	625_R	1.749	0.98
528_V	591_L	1.749	0.98
554_D	601_R	1.748	0.98
573_E	577_D	1.747	0.98
548_S	609_Q	1.743	0.98
105_T	109_Y	1.741	0.98
403_E	415_N	1.739	0.98
576_W	582_K	1.697	0.97
159_D	162_G	1.696	0.97
205_F	209_L	1.695	0.97
595_H	604_I	1.687	0.97
547_I	576_W	1.686	0.97
538_V	653_F	1.682	0.97
425_E	430_Y	1.664	0.97
202_W	205_F	1.653	0.97
105_T	108_P	1.647	0.97
584_A	587_V	1.646	0.97
545_N	609_Q	1.642	0.96
72_S	116_W	1.641	0.96
184_L	188_K	1.632	0.96
448_Y	451_E	1.615	0.96
622_K	648_Y	1.613	0.96
57_V	97_E	1.610	0.96
247_S	310_W	1.609	0.96
440_P	469_G	1.608	0.96
424_M	461_A	1.604	0.96
282_C	285_E	1.603	0.96
387_G	390_D	1.594	0.96
583_Y	586_N	1.594	0.96
122_S	125_V	1.593	0.96
615_K	621_T	1.577	0.96
538_V	649_I	1.575	0.96
148_P	156_Y	1.571	0.95
419_M	456_A	1.563	0.95
486_G	522_F	1.563	0.95
257_G	260_K	1.562	0.95
140_K	143_Q	1.553	0.95
284_T	332_I	1.550	0.95
501_I	507_I	1.549	0.95
541_R	633_L	1.546	0.95
437_H	470_S	1.546	0.95
273_Y	277_Q	1.533	0.95
104_L	108_P	1.529	0.95
106_D	109_Y	1.525	0.95
244_S	247_S	1.525	0.95
538_V	592_L	1.524	0.95
494_M	531_T	1.516	0.94
501_I	504_D	1.514	0.94
162_G	165_R	1.506	0.94
525_N	542_S	1.494	0.94
539_T	542_S	1.494	0.94
49_Y	53_T	1.493	0.94
604_I	608_E	1.491	0.94
606_Q	609_Q	1.487	0.94
537_A	589_T	1.486	0.94
92_Y	98_G	1.485	0.94
469_G	492_D	1.484	0.94
156_Y	160_G	1.483	0.94
138_R	141_T	1.482	0.94
202_W	223_I	1.480	0.94
436_I	523_M	1.472	0.94
386_T	389_N	1.471	0.94
377_P	380_Q	1.464	0.93
344_E	347_Y	1.464	0.93
149_V	152_Q	1.460	0.93
461_A	507_I	1.457	0.93
62_G	66_S	1.452	0.93
424_M	427_E	1.443	0.93
149_V	156_Y	1.441	0.93
541_R	602_C	1.440	0.93
571_D	574_K	1.436	0.93
103_K	107_I	1.424	0.92
141_T	144_D	1.419	0.92
530_Q	583_Y	1.418	0.92
425_E	461_A	1.415	0.92
182_K	185_T	1.409	0.92
28_A	51_T	1.407	0.92
383_K	386_T	1.402	0.92
548_S	606_Q	1.399	0.92
372_E	386_T	1.398	0.92
154_L	157_K	1.397	0.92
546_W	560_T	1.391	0.91
174_V	178_S	1.387	0.91
536_A	590_P	1.384	0.91
346_E	349_N	1.381	0.91
111_V	114_P	1.372	0.91
152_Q	157_K	1.365	0.91
50_E	53_T	1.362	0.91
526_W	530_Q	1.361	0.91
260_K	266_T	1.360	0.91
517_G	601_R	1.354	0.90
517_G	645_R	1.351	0.90
153_G	156_Y	1.347	0.90
439_G	469_G	1.341	0.90
223_I	246_F	1.334	0.90
50_E	54_G	1.329	0.89
183_E	186_S	1.323	0.89
594_L	624_V	1.320	0.89
344_E	351_F	1.313	0.89
46_I	49_Y	1.313	0.89
157_K	163_L	1.305	0.89
138_R	142_E	1.292	0.88
434_L	463_V	1.286	0.88
510_K	535_K	1.285	0.88
181_M	185_T	1.284	0.88
166_G	169_A	1.277	0.87
120_G	125_V	1.274	0.87
410_D	468_R	1.268	0.87
626_F	648_Y	1.246	0.86
30_Y	56_S	1.242	0.86
494_M	534_F	1.238	0.86
66_S	69_P	1.222	0.85
600_D	630_S	1.221	0.85
150_E	157_K	1.218	0.85
114_P	123_I	1.216	0.85
622_K	652_W	1.215	0.85
119_D	125_V	1.205	0.84
274_D	278_G	1.204	0.84
252_Y	256_L	1.204	0.84
171_L	177_K	1.202	0.84
528_V	589_T	1.202	0.84
424_M	428_T	1.196	0.84
156_Y	163_L	1.194	0.84
117_S	121_E	1.190	0.83
23_P	71_W	1.185	0.83
473_Y	517_G	1.180	0.83
254_A	310_W	1.176	0.83
467_P	523_M	1.176	0.83
91_L	111_V	1.174	0.83
539_T	591_L	1.171	0.82
221_V	224_M	1.164	0.82
564_L	575_L	1.160	0.82
494_M	498_D	1.158	0.82
424_M	429_T	1.158	0.82
537_A	591_L	1.153	0.81
77_T	93_I	1.152	0.81
597_E	625_R	1.151	0.81
404_I	416_G	1.150	0.81
424_M	507_I	1.148	0.81
53_T	57_V	1.147	0.81
519_Y	523_M	1.146	0.81
536_A	653_F	1.144	0.81
255_L	280_L	1.135	0.80
525_N	544_S	1.134	0.80
491_D	495_Q	1.134	0.80
160_G	164_T	1.131	0.80
346_E	353_L	1.128	0.80
149_V	157_K	1.125	0.80
252_Y	274_D	1.122	0.80
29_A	59_W	1.119	0.79
103_K	108_P	1.106	0.79
153_G	157_K	1.103	0.78
148_P	160_G	1.100	0.78
91_L	98_G	1.094	0.78
22_A	71_W	1.090	0.78
437_H	467_P	1.090	0.78
325_G	473_Y	1.090	0.78
116_W	123_I	1.086	0.77
437_H	466_N	1.085	0.77
633_L	646_L	1.083	0.77
484_D	488_K	1.082	0.77
170_Q	174_V	1.082	0.77
204_V	223_I	1.081	0.77
494_M	533_R	1.079	0.77
152_Q	156_Y	1.077	0.77
277_Q	281_T	1.077	0.77
198_P	246_F	1.071	0.76
359_H	375_S	1.068	0.76
197_S	246_F	1.067	0.76
46_I	69_P	1.065	0.76
419_M	464_Y	1.065	0.76
374_Y	384_Q	1.064	0.76
81_I	106_D	1.063	0.76
328_G	342_R	1.062	0.76
146_Y	149_V	1.061	0.76
27_R	48_I	1.060	0.76
127_V	130_G	1.057	0.75
269_K	282_C	1.057	0.75
406_Y	495_Q	1.056	0.75
284_T	287_L	1.055	0.75
444_Y	464_Y	1.055	0.75
253_L	275_I	1.054	0.75
274_D	279_R	1.054	0.75
117_S	125_V	1.053	0.75
438_G	469_G	1.052	0.75
204_V	207_A	1.051	0.75
110_G	114_P	1.050	0.75
438_G	467_P	1.044	0.75
79_A	116_W	1.042	0.74
458_K	650_S	1.040	0.74
421_P	430_Y	1.034	0.74
145_S	160_G	1.032	0.74
552_V	605_E	1.029	0.73
321_G	330_Y	1.027	0.73
595_H	607_A	1.026	0.73
176_V	179_G	1.021	0.73
157_K	160_G	1.021	0.73
319_V	332_I	1.021	0.73
593_I	610_L	1.019	0.73
171_L	174_V	1.019	0.73
347_Y	353_L	1.017	0.73
485_Y	519_Y	1.016	0.72
31_V	69_P	1.016	0.72
432_L	497_V	1.012	0.72
635_R	641_Q	1.011	0.72
329_I	360_F	1.011	0.72
69_P	80_F	1.008	0.72
449_F	452_F	1.007	0.72
559_F	562_W	1.006	0.72
313_D	316_G	1.003	0.72
490_Y	526_W	1.000	0.71
259_E	266_T	1.000	0.71
426_G	430_Y	1.000	0.71
591_L	621_T	0.999	0.71
72_S	75_G	0.997	0.71
465_I	496_A	0.996	0.71
440_P	492_D	0.994	0.71
92_Y	103_K	0.988	0.70
404_I	463_V	0.984	0.70
406_Y	465_I	0.983	0.70
55_G	76_R	0.981	0.70
345_K	351_F	0.980	0.70
439_G	492_D	0.979	0.70
325_G	417_W	0.979	0.70
124_L	127_V	0.973	0.69
138_R	144_D	0.967	0.69
633_L	645_R	0.967	0.69
433_I	460_Y	0.963	0.68
522_F	526_W	0.962	0.68
438_G	492_D	0.959	0.68
391_K	423_Q	0.957	0.68
347_Y	351_F	0.956	0.68
429_T	508_D	0.956	0.68
361_I	373_L	0.954	0.68
112_S	115_L	0.951	0.67
90_Q	103_K	0.947	0.67
365_T	371_S	0.945	0.67
326_S	446_H	0.941	0.67
116_W	125_V	0.940	0.66
69_P	74_D	0.937	0.66
436_I	493_V	0.935	0.66
164_T	167_A	0.934	0.66
45_N	58_P	0.934	0.66
119_D	124_L	0.933	0.66
54_G	57_V	0.932	0.66
385_L	389_N	0.932	0.66
472_G	585_A	0.931	0.66
611_F	621_T	0.931	0.66
247_S	254_A	0.930	0.66
597_E	604_I	0.930	0.66
529_G	587_V	0.930	0.66
223_I	232_K	0.929	0.66
542_S	607_A	0.929	0.66
136_D	140_K	0.926	0.65
410_D	491_D	0.926	0.65
408_T	491_D	0.924	0.65
80_F	83_D	0.920	0.65
249_D	314_S	0.919	0.65
40_D	47_W	0.919	0.65
222_Y	233_Q	0.917	0.65
420_R	461_A	0.914	0.64
160_G	167_A	0.912	0.64
152_Q	155_S	0.911	0.64
94_M	97_E	0.911	0.64
257_G	266_T	0.910	0.64
94_M	101_A	0.910	0.64
252_Y	260_K	0.910	0.64
138_R	143_Q	0.909	0.64
628_N	635_R	0.906	0.64
402_E	503_R	0.906	0.64
549_F	601_R	0.905	0.64
434_L	497_V	0.905	0.64
332_I	338_V	0.904	0.63
591_L	610_L	0.903	0.63
154_L	159_D	0.902	0.63
81_I	91_L	0.900	0.63
540_Q	645_R	0.898	0.63
420_R	424_M	0.897	0.63
608_E	625_R	0.894	0.63
51_T	54_G	0.892	0.62
171_L	176_V	0.892	0.62
165_R	168_Y	0.890	0.62
576_W	581_L	0.889	0.62
77_T	80_F	0.887	0.62
432_L	512_L	0.886	0.62
414_V	477_F	0.885	0.62
129_L	138_R	0.884	0.62
540_Q	626_F	0.884	0.62
524_T	591_L	0.881	0.61
426_G	507_I	0.879	0.61
139_E	143_Q	0.878	0.61
70_R	114_P	0.877	0.61
28_A	49_Y	0.877	0.61
77_T	120_G	0.872	0.61
397_T	423_Q	0.871	0.61
541_R	645_R	0.871	0.61
148_P	152_Q	0.871	0.61
428_T	461_A	0.869	0.60
416_G	628_N	0.867	0.60
519_Y	522_F	0.865	0.60
541_R	601_R	0.865	0.60
117_S	124_L	0.865	0.60
382_E	385_L	0.863	0.60
102_R	105_T	0.861	0.60
146_Y	152_Q	0.859	0.59
485_Y	563_Q	0.857	0.59
158_R	163_L	0.857	0.59
118_P	124_L	0.854	0.59
157_K	162_G	0.849	0.59
562_W	603_P	0.849	0.59
52_K	55_G	0.848	0.58
252_Y	272_L	0.847	0.58
155_S	158_R	0.843	0.58
46_I	59_W	0.841	0.58
384_Q	389_N	0.838	0.58
539_T	593_I	0.838	0.58
525_N	591_L	0.837	0.57
113_K	126_T	0.835	0.57
385_L	388_A	0.833	0.57
515_T	653_F	0.832	0.57
26_T	50_E	0.829	0.57
165_R	172_V	0.828	0.57
346_E	351_F	0.828	0.57
135_I	138_R	0.828	0.57
136_D	139_E	0.827	0.57
362_A	376_I	0.825	0.56
467_P	493_V	0.822	0.56
277_Q	280_L	0.822	0.56
412_V	477_F	0.822	0.56
137_D	142_E	0.821	0.56
110_G	113_K	0.819	0.56
31_V	46_I	0.819	0.56
408_T	412_V	0.819	0.56
585_A	617_M	0.819	0.56
118_P	200_G	0.819	0.56
170_Q	187_H	0.818	0.56
78_L	95_S	0.817	0.56
348_I	351_F	0.815	0.55
430_Y	507_I	0.815	0.55
276_E	279_R	0.813	0.55
529_G	610_L	0.811	0.55
45_N	66_S	0.810	0.55
132_G	138_R	0.807	0.55
404_I	503_R	0.805	0.54
558_F	561_D	0.803	0.54
541_R	632_N	0.802	0.54
256_L	260_K	0.802	0.54
158_R	161_K	0.802	0.54
150_E	154_L	0.802	0.54
474_G	492_D	0.800	0.54
475_Q	479_N	0.799	0.54
120_G	124_L	0.797	0.54
563_Q	569_F	0.797	0.54
577_D	582_K	0.796	0.54
540_Q	633_L	0.795	0.54
159_D	164_T	0.794	0.53
166_G	171_L	0.794	0.53
437_H	489_D	0.793	0.53
345_K	349_N	0.793	0.53
626_F	629_A	0.792	0.53
318_Y	331_Y	0.792	0.53
201_K	423_Q	0.788	0.53
434_L	481_V	0.788	0.53
50_E	91_L	0.786	0.53
531_T	589_T	0.786	0.53
53_T	56_S	0.785	0.53
489_D	519_Y	0.785	0.53
311_T	315_Q	0.784	0.53
139_E	142_E	0.784	0.53
174_V	181_M	0.783	0.52
103_K	109_Y	0.780	0.52
466_N	470_S	0.780	0.52
361_I	375_S	0.780	0.52
57_V	76_R	0.778	0.52
40_D	640_R	0.777	0.52
177_K	180_E	0.776	0.52
436_I	552_V	0.775	0.52
31_V	44_S	0.773	0.52
481_V	519_Y	0.772	0.51
329_I	362_A	0.771	0.51
587_V	591_L	0.768	0.51
247_S	250_G	0.765	0.51
459_G	580_P	0.764	0.51
94_M	100_E	0.761	0.50
511_R	608_E	0.759	0.50
150_E	156_Y	0.758	0.50
256_L	259_E	0.758	0.50
634_S	645_R	0.757	0.50
154_L	158_R	0.754	0.50
526_W	583_Y	0.754	0.50
485_Y	559_F	0.754	0.50
274_D	280_L	0.753	0.50
50_E	55_G	0.751	0.49
370_P	393_V	0.750	0.49
553_S	602_C	0.749	0.49
137_D	143_Q	0.749	0.49
476_E	480_A	0.748	0.49
149_V	158_R	0.747	0.49
121_E	125_V	0.746	0.49
220_D	224_M	0.746	0.49
635_R	645_R	0.746	0.49
33_S	45_N	0.744	0.49
329_I	341_I	0.741	0.49
490_Y	531_T	0.739	0.48
362_A	382_E	0.738	0.48
541_R	595_H	0.737	0.48
445_G	451_E	0.737	0.48
444_Y	467_P	0.736	0.48
34_Q	48_I	0.736	0.48
633_L	642_R	0.734	0.48
338_V	342_R	0.733	0.48
145_S	156_Y	0.733	0.48
400_I	420_R	0.732	0.48
146_Y	150_E	0.731	0.48
467_P	486_G	0.731	0.48
204_V	221_V	0.730	0.47
613_A	617_M	0.730	0.47
140_K	144_D	0.730	0.47
29_A	48_I	0.729	0.47
118_P	125_V	0.729	0.47
237_H	241_F	0.729	0.47
173_L	177_K	0.728	0.47
469_G	474_G	0.728	0.47
197_S	205_F	0.728	0.47
165_R	169_A	0.726	0.47
51_T	57_V	0.724	0.47
381_E	389_N	0.723	0.47
223_I	226_L	0.722	0.47
269_K	284_T	0.722	0.47
489_D	546_W	0.721	0.47
76_R	97_E	0.721	0.47
517_G	554_D	0.720	0.47
136_D	143_Q	0.719	0.46
444_Y	489_D	0.719	0.46
517_G	633_L	0.718	0.46
475_Q	478_V	0.717	0.46
438_G	474_G	0.716	0.46
401_P	453_Q	0.716	0.46
468_R	480_A	0.716	0.46
479_N	482_R	0.714	0.46
247_S	255_L	0.713	0.46
72_S	79_A	0.713	0.46
94_M	99_G	0.713	0.46
467_P	489_D	0.713	0.46
146_Y	157_K	0.711	0.46
572_T	576_W	0.711	0.46
168_Y	171_L	0.711	0.46
64_K	83_D	0.710	0.46
522_F	546_W	0.709	0.46
415_N	473_Y	0.708	0.45
425_E	507_I	0.708	0.45
124_L	196_F	0.707	0.45
543_I	559_F	0.706	0.45
33_S	65_R	0.704	0.45
467_P	481_V	0.704	0.45
224_M	228_S	0.703	0.45
402_E	426_G	0.703	0.45
522_F	545_N	0.701	0.45
523_M	526_W	0.699	0.45
201_K	339_Y	0.699	0.45
147_E	156_Y	0.699	0.45
253_L	257_G	0.698	0.45
336_G	373_L	0.698	0.45
133_E	138_R	0.695	0.44
104_L	109_Y	0.695	0.44
470_S	492_D	0.694	0.44
555_I	559_F	0.693	0.44
451_E	645_R	0.693	0.44
346_E	354_S	0.692	0.44
139_E	144_D	0.692	0.44
258_N	266_T	0.691	0.44
24_D	27_R	0.691	0.44
541_R	635_R	0.691	0.44
549_F	553_S	0.690	0.44
232_K	235_T	0.690	0.44
319_V	338_V	0.689	0.44
90_Q	96_T	0.685	0.43
271_W	277_Q	0.685	0.43
543_I	546_W	0.685	0.43
574_K	577_D	0.684	0.43
346_E	350_S	0.683	0.43
320_I	327_T	0.683	0.43
117_S	120_G	0.682	0.43
227_E	588_E	0.682	0.43
79_A	93_I	0.681	0.43
440_P	466_N	0.681	0.43
203_L	208_N	0.681	0.43
132_G	137_D	0.680	0.43
412_V	480_A	0.676	0.42
493_V	496_A	0.676	0.42
42_Y	49_Y	0.675	0.42
153_G	162_G	0.675	0.42
234_V	249_D	0.673	0.42
22_A	26_T	0.671	0.42
545_N	580_P	0.671	0.42
488_K	491_D	0.671	0.42
421_P	508_D	0.670	0.42
433_I	455_L	0.668	0.42
402_E	418_L	0.667	0.42
428_T	507_I	0.662	0.41
95_S	102_R	0.662	0.41
541_R	600_D	0.659	0.41
549_F	555_I	0.659	0.41
372_E	388_A	0.659	0.41
356_D	359_H	0.658	0.41
348_I	353_L	0.657	0.41
22_A	25_G	0.657	0.41
515_T	549_F	0.657	0.41
549_F	603_P	0.656	0.41
57_V	77_T	0.655	0.41
541_R	629_A	0.653	0.40
95_S	100_E	0.652	0.40
544_S	610_L	0.652	0.40
470_S	474_G	0.650	0.40
248_P	272_L	0.650	0.40
253_L	258_N	0.649	0.40
435_N	515_T	0.649	0.40
62_G	82_S	0.649	0.40
439_G	470_S	0.648	0.40
401_P	419_M	0.648	0.40
106_D	377_P	0.648	0.40
184_L	187_H	0.647	0.40
253_L	259_E	0.647	0.40
493_V	563_Q	0.647	0.40
540_Q	634_S	0.647	0.40
221_V	251_R	0.647	0.40
117_S	196_F	0.646	0.40
449_F	634_S	0.646	0.40
383_K	388_A	0.646	0.40
335_E	655_Q	0.646	0.40
322_T	472_G	0.645	0.40
467_P	526_W	0.644	0.40
131_E	135_I	0.644	0.40
93_I	104_L	0.644	0.40
412_V	476_E	0.643	0.40
65_R	83_D	0.643	0.40
496_A	523_M	0.642	0.39
437_H	440_P	0.640	0.39
22_A	70_R	0.640	0.39
152_Q	160_G	0.639	0.39
119_D	122_S	0.639	0.39
29_A	71_W	0.638	0.39
94_M	102_R	0.637	0.39
620_E	656_H	0.637	0.39
535_K	586_N	0.636	0.39
440_P	470_S	0.636	0.39
29_A	51_T	0.635	0.39
251_R	429_T	0.635	0.39
443_M	472_G	0.635	0.39
515_T	649_I	0.634	0.39
49_Y	54_G	0.634	0.39
364_V	369_R	0.632	0.39
257_G	271_W	0.632	0.39
30_Y	71_W	0.632	0.39
515_T	540_Q	0.631	0.38
461_A	500_A	0.631	0.38
91_L	104_L	0.630	0.38
486_G	489_D	0.629	0.38
115_L	126_T	0.629	0.38
406_Y	463_V	0.629	0.38
72_S	76_R	0.629	0.38
79_A	114_P	0.628	0.38
214_D	217_K	0.628	0.38
401_P	464_Y	0.628	0.38
587_V	614_L	0.627	0.38
423_Q	427_E	0.627	0.38
167_A	171_L	0.627	0.38
432_L	535_K	0.626	0.38
168_Y	173_L	0.625	0.38
48_I	56_S	0.625	0.38
559_F	563_Q	0.625	0.38
149_V	153_G	0.625	0.38
324_Q	405_Q	0.624	0.38
148_P	159_D	0.623	0.38
132_G	136_D	0.621	0.38
391_K	395_E	0.621	0.38
120_G	123_I	0.620	0.37
124_L	203_L	0.619	0.37
20_Q	46_I	0.619	0.37
405_Q	415_N	0.618	0.37
345_K	353_L	0.617	0.37
398_I	453_Q	0.617	0.37
438_G	468_R	0.616	0.37
473_Y	601_R	0.615	0.37
66_S	82_S	0.614	0.37
543_I	602_C	0.614	0.37
49_Y	56_S	0.612	0.37
149_V	159_D	0.612	0.37
203_L	242_G	0.612	0.37
182_K	229_G	0.612	0.37
18_D	69_P	0.612	0.37
493_V	549_F	0.612	0.37
362_A	374_Y	0.610	0.37
559_F	626_F	0.608	0.36
172_V	176_V	0.607	0.36
283_L	404_I	0.607	0.36
54_G	63_E	0.607	0.36
145_S	154_L	0.606	0.36
191_H	194_P	0.606	0.36
286_M	655_Q	0.605	0.36
420_R	430_Y	0.605	0.36
525_N	537_A	0.605	0.36
550_H	559_F	0.604	0.36
124_L	194_P	0.603	0.36
536_A	652_W	0.602	0.36
374_Y	386_T	0.602	0.36
624_V	652_W	0.601	0.36
489_D	578_R	0.600	0.36
135_I	141_T	0.599	0.36
136_D	141_T	0.599	0.36
432_L	500_A	0.598	0.36
62_G	100_E	0.598	0.36
589_T	611_F	0.598	0.36
73_P	120_G	0.597	0.35
451_E	517_G	0.597	0.35
494_M	527_I	0.597	0.35
156_Y	159_D	0.596	0.35
590_P	652_W	0.595	0.35
651_S	655_Q	0.594	0.35
201_K	225_S	0.594	0.35
626_F	633_L	0.593	0.35
539_T	626_F	0.592	0.35
408_T	432_L	0.592	0.35
543_I	575_L	0.592	0.35
417_W	467_P	0.591	0.35
89_A	92_Y	0.591	0.35
42_Y	47_W	0.591	0.35
147_E	150_E	0.590	0.35
513_G	652_W	0.590	0.35
519_Y	563_Q	0.589	0.35
146_Y	153_G	0.589	0.35
27_R	77_T	0.589	0.35
136_D	197_S	0.588	0.35
163_L	166_G	0.587	0.35
28_A	56_S	0.587	0.35
147_E	158_R	0.587	0.35
596_G	633_L	0.586	0.35
425_E	506_H	0.586	0.35
254_A	272_L	0.584	0.34
146_Y	158_R	0.584	0.34
587_V	621_T	0.583	0.34
589_T	652_W	0.582	0.34
493_V	562_W	0.582	0.34
525_N	528_V	0.580	0.34
441_H	471_H	0.580	0.34
512_L	609_Q	0.579	0.34
80_F	101_A	0.579	0.34
275_I	278_G	0.579	0.34
148_P	155_S	0.579	0.34
441_H	478_V	0.578	0.34
130_G	133_E	0.578	0.34
156_Y	162_G	0.577	0.34
118_P	123_I	0.577	0.34
485_Y	489_D	0.577	0.34
439_G	466_N	0.576	0.34
323_D	328_G	0.575	0.34
183_E	187_H	0.575	0.34
517_G	549_F	0.575	0.34
539_T	610_L	0.573	0.33
226_L	233_Q	0.573	0.33
145_S	155_S	0.573	0.33
171_L	178_S	0.573	0.33
119_D	123_I	0.572	0.33
383_K	387_G	0.569	0.33
124_L	135_I	0.569	0.33
353_L	360_F	0.568	0.33
422_A	457_A	0.566	0.33
559_F	564_L	0.566	0.33
541_R	596_G	0.566	0.33
270_A	407_A	0.566	0.33
24_D	28_A	0.565	0.33
408_T	545_N	0.565	0.33
447_T	451_E	0.565	0.33
514_V	537_A	0.565	0.33
174_V	179_G	0.564	0.33
394_R	584_A	0.564	0.33
275_I	341_I	0.563	0.33
76_R	95_S	0.563	0.33
133_E	142_E	0.563	0.33
224_M	231_L	0.562	0.33
117_S	122_S	0.562	0.33
310_W	529_G	0.562	0.33
422_A	653_F	0.562	0.33
402_E	419_M	0.562	0.33
437_H	518_S	0.562	0.33
73_P	118_P	0.561	0.32
25_G	46_I	0.558	0.32
549_F	595_H	0.558	0.32
417_W	466_N	0.558	0.32
514_V	632_N	0.556	0.32
329_I	429_T	0.556	0.32
486_G	519_Y	0.555	0.32
221_V	228_S	0.555	0.32
612_I	616_K	0.553	0.32
517_G	649_I	0.553	0.32
626_F	635_R	0.553	0.32
519_Y	595_H	0.553	0.32
177_K	181_M	0.552	0.32
21_Y	75_G	0.551	0.32
487_G	578_R	0.551	0.32
52_K	93_I	0.551	0.32
39_K	43_T	0.550	0.32
244_S	250_G	0.550	0.32
20_Q	30_Y	0.550	0.32
540_Q	649_I	0.549	0.31
620_E	647_N	0.549	0.31
487_G	494_M	0.549	0.31
457_A	534_F	0.549	0.31
43_T	81_I	0.548	0.31
33_S	44_S	0.548	0.31
444_Y	451_E	0.546	0.31
284_T	336_G	0.546	0.31
254_A	317_F	0.546	0.31
459_G	462_V	0.545	0.31
123_I	137_D	0.545	0.31
485_Y	560_T	0.545	0.31
549_F	562_W	0.544	0.31
320_I	328_G	0.544	0.31
218_P	224_M	0.543	0.31
129_L	132_G	0.543	0.31
441_H	542_S	0.543	0.31
408_T	495_Q	0.542	0.31
269_K	286_M	0.542	0.31
34_Q	43_T	0.541	0.31
118_P	196_F	0.540	0.31
485_Y	526_W	0.539	0.31
548_S	551_G	0.539	0.31
481_V	493_V	0.539	0.31
67_T	81_I	0.538	0.31
453_Q	457_A	0.537	0.31
90_Q	97_E	0.537	0.31
486_G	523_M	0.537	0.31
196_F	200_G	0.537	0.31
90_Q	101_A	0.537	0.31
275_I	288_D	0.535	0.30
437_H	601_R	0.535	0.30
91_L	95_S	0.534	0.30
102_R	107_I	0.533	0.30
19_P	46_I	0.533	0.30
259_E	271_W	0.532	0.30
529_G	583_Y	0.531	0.30
27_R	96_T	0.530	0.30
147_E	155_S	0.530	0.30
555_I	601_R	0.530	0.30
169_A	173_L	0.529	0.30
407_A	535_K	0.529	0.30
486_G	526_W	0.529	0.30
171_L	175_S	0.528	0.30
102_R	106_D	0.528	0.30
438_G	466_N	0.527	0.30
432_L	550_H	0.527	0.30
429_T	655_Q	0.527	0.30
565_E	574_K	0.526	0.30
27_R	83_D	0.526	0.30
148_P	154_L	0.525	0.30
190_D	216_S	0.524	0.29
391_K	398_I	0.524	0.29
49_Y	102_R	0.524	0.29
136_D	142_E	0.523	0.29
127_V	132_G	0.522	0.29
78_L	82_S	0.522	0.29
92_Y	101_A	0.522	0.29
584_A	613_A	0.521	0.29
437_H	517_G	0.521	0.29
73_P	81_I	0.519	0.29
31_V	78_L	0.519	0.29
271_W	282_C	0.519	0.29
202_W	207_A	0.519	0.29
420_R	426_G	0.519	0.29
542_S	546_W	0.518	0.29
438_G	523_M	0.517	0.29
195_A	246_F	0.517	0.29
419_M	452_F	0.517	0.29
454_V	458_K	0.517	0.29
507_I	626_F	0.516	0.29
64_K	67_T	0.516	0.29
198_P	205_F	0.515	0.29
490_Y	523_M	0.515	0.29
135_I	139_E	0.514	0.29
545_N	548_S	0.513	0.29
497_V	533_R	0.513	0.29
78_L	81_I	0.513	0.29
186_S	189_A	0.512	0.29
417_W	453_Q	0.509	0.28
106_D	114_P	0.508	0.28
624_V	648_Y	0.508	0.28
317_F	332_I	0.508	0.28
22_A	27_R	0.507	0.28
475_Q	633_L	0.507	0.28
204_V	651_S	0.507	0.28
272_L	334_I	0.507	0.28
463_V	493_V	0.507	0.28
444_Y	448_Y	0.506	0.28
92_Y	95_S	0.506	0.28
266_T	271_W	0.505	0.28
244_S	254_A	0.505	0.28
47_W	56_S	0.505	0.28
591_L	652_W	0.505	0.28
491_D	527_I	0.505	0.28
269_K	291_L	0.505	0.28
553_S	601_R	0.504	0.28
417_W	639_P	0.504	0.28
251_R	428_T	0.504	0.28
528_V	610_L	0.503	0.28
291_L	319_V	0.502	0.28
540_Q	632_N	0.502	0.28
611_F	623_L	0.502	0.28
91_L	114_P	0.501	0.28
240_S	260_K	0.501	0.28
433_I	513_G	0.500	0.28
403_E	615_K	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1xfdA	2	0.9346	100	0.401	Contact Map
4wjlA	2	0.9346	100	0.414	Contact Map
4hxfB	4	0.898	100	0.414	Contact Map
4a5sA	2	0.9269	100	0.419	Contact Map
1z68A	2	0.9239	100	0.425	Contact Map
2z3zA	2	0.8752	100	0.429	Contact Map
2ecfA	2	0.9224	100	0.431	Contact Map
4q1vA	2	0.9178	100	0.431	Contact Map
3o4hA	2	0.8311	100	0.496	Contact Map
3azoA	1	0.9102	100	0.5	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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