GLTA - BACSU - GREMLIN Contacts

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GLTA - Glutamate synthase [NADPH] large chain

UniProt:	P39812	Sequences: MTYNQMPKAQGLYRPEFEHDACGIGLYAHLKGKQTHDIVKQGLKMLCQLDHRGGQGSDPDTGDGAGLLVQIPDAFFRKECKNINLPEKERYGVGMVFFSQKEDERKKIEKQINALIEQEGQVVLGWRTVPVNVGKIGTVAQKSCPFVRQVFIGASSDLKDNLSFERKLYVIRKQAENWGVTEGLDFYFASLSSQTIVYKGLLTPEQVDAFYSDLQDEAFVSAFALVHSRFSTNTFPTWERAHPNRYLVHNGEINTLRGNINWMRAREQQFVSESFGEDLNKILPILNADGSDSSILDNAFEFFVMAGRKPAHTAMMLIPEPWTENTHMSKEKRAFYEYHSSLMEPWDGPTAISFTDGKQIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVEQENVLYKNRLEPGKMLLIDLEEGRIISDEEVKTQIATEYPYQKWLEEELVQVNPDPESREEEQFSDLLTRQKAFGYTYEDIQKYLIPVIKEGKDPLGSMGNDAPLAVLSDRAQSLFNYFKQLFAQVTNPPIDAIREQLVTSTMTWLGAEGDLLHPSERNVRRIKLYTPVLSNEQFYALKTIVHPDLKSQKIDVLFSEDLERGLKDMFTQAEKAISQGVSLLILSDKKMNERLTPIPPLLAVSALHQHLIRKGLRTKVSIIVESGEAREVHHFAALIGYGADAINPYLAYATYKQEIDEGRLDISYEEAVSKYGKSITEGVVKVMSKMGISTVQSYRGAQIFEAVGISRDVIDRYFSGTASQLGGIDLQTIAEEAQRRHREAYQDDYSKTLEPGSDFQWRNGGEHHAFNPKTIHTLQWACRRNDYNLFKQYTKAADEERIGFLRNLFAFDGNRKPLKLEEVESAESIVKRFKTGAMSFGSLSKEAHEALAIAMNRLGGKSNSGEGGEDPKRFVPDENGDDRRSAIKQIASGRFGVKSHYLVNADELQIKMAQGAKPGEGGQLPGNKVYPWVADVRGSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANRDARISVKLVSKAGVGTIAAGVAKATADVIVISGYDGGTGASPKTSIKHTGLPWELGLAEAHQTLMLNGLRDRVVLETDGKLMTGRDVVMAALLGAEEFGFATAPLVVLGCVMMRACHLDTCPVGVATQNPELRKKFMGDPDHIVNYMLFIAEEVREYMAALGFKTFDEMIGRTDVLHASERAKEHWKASQLDLSTLLYQPEGVRTFQSPQNHKIDQSLDITTILPAVQEAIESGKEADISIEINNTNRVAGTITGSEISKRYGEEGLPEDTIKLHFTGSAGQSFGAFVPKGMTLYLDGDSNDYVGKGLSGGKIIVKSSEGFNSASDDNVIIGNVAFYGATSGEAYINGRAGERFAVRNSGVNVVVEGIGDHGCEYMTGGSVVVLGDVGKNFAAGMSGGIAYVLTEDVKAFKRKCNLEMILFESLEDEKEIQQIKAMLERHTAYTNSQKAEDLLDQWEDSVKKFVKVIPKNYKQMLASIEEQKAAGLSDEEAIMFAFEANTKPKQNTAASGQKQAVVQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	1520 (1457)
Sequences:	2337 (1087)
Seq/√Len:	28.5

ECOLI - GLTB
BACSU - GLTA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
1444_T	1452_A	6.564	1.00
585_I	600_M	6.510	1.00
1168_T	1171_E	5.653	1.00
1346_E	1442_R	5.331	1.00
73_D	77_R	5.084	1.00
31_K	380_D	5.058	1.00
78_K	218_A	4.927	1.00
1032_I	1076_V	4.922	1.00
318_I	352_I	4.808	1.00
657_S	660_A	4.805	1.00
69_V	219_F	4.782	1.00
1091_V	1157_V	4.749	1.00
1166_F	1172_M	4.718	1.00
824_Y	1149_Y	4.717	1.00
74_A	220_V	4.717	1.00
510_F	631_P	4.697	1.00
144_C	210_F	4.666	1.00
585_I	604_A	4.602	1.00
378_K	397_N	4.454	1.00
853_E	1167_K	4.321	1.00
109_E	148_R	4.144	1.00
1406_L	1462_S	4.133	1.00
296_L	317_L	4.074	1.00
821_F	825_T	4.063	1.00
39_V	221_S	4.007	1.00
1229_A	1244_I	3.988	1.00
604_A	615_L	3.975	1.00
334_A	436_Q	3.963	1.00
1261_I	1295_M	3.942	1.00
857_A	1155_E	3.875	1.00
1287_F	1297_L	3.813	1.00
1385_V	1436_I	3.732	1.00
1032_I	1078_L	3.605	1.00
813_C	1110_V	3.603	1.00
1348_Y	1442_R	3.558	1.00
1427_L	1436_I	3.551	1.00
861_V	889_L	3.529	1.00
623_N	626_L	3.497	1.00
1246_I	1279_F	3.412	1.00
921_I	939_L	3.409	1.00
760_D	763_T	3.398	1.00
1017_V	1034_I	3.371	1.00
37_D	41_Q	3.361	1.00
915_R	937_D	3.337	1.00
482_V	709_S	3.329	1.00
1170_D	1208_T	3.311	1.00
666_F	710_I	3.294	1.00
1080_T	1093_A	3.292	1.00
917_A	937_D	3.267	1.00
742_R	746_D	3.258	1.00
1371_I	1375_G	3.255	1.00
1161_M	1172_M	3.214	1.00
594_E	747_R	3.212	1.00
843_D	1180_H	3.195	1.00
698_S	701_E	3.192	1.00
1383_S	1435_Q	3.174	1.00
76_F	196_I	3.140	1.00
29_H	33_K	3.133	1.00
121_Q	171_I	3.127	1.00
94_G	191_L	3.089	1.00
152_I	191_L	3.087	1.00
1004_D	1263_K	3.078	1.00
1458_Q	1461_D	3.078	1.00
1134_E	1137_K	3.068	1.00
822_K	1159_E	3.061	1.00
841_A	1180_H	3.044	1.00
487_K	712_E	3.026	1.00
418_R	424_E	3.010	1.00
1358_A	1384_V	3.000	1.00
383_I	393_V	2.986	1.00
1091_V	1160_Y	2.947	1.00
1395_A	1422_I	2.944	1.00
605_E	645_K	2.919	1.00
934_V	1259_S	2.918	1.00
856_S	859_S	2.914	1.00
1101_F	1173_I	2.883	1.00
583_Q	612_V	2.882	1.00
112_I	175_A	2.864	1.00
609_S	647_L	2.823	1.00
128_T	148_R	2.815	1.00
672_Y	752_T	2.809	1.00
742_R	757_G	2.801	1.00
566_N	678_N	2.795	1.00
1166_F	1178_V	2.793	1.00
1291_V	1295_M	2.793	1.00
1167_K	1171_E	2.791	1.00
881_A	1111_L	2.783	1.00
1278_H	1298_Y	2.776	1.00
586_D	626_L	2.772	1.00
1234_I	1265_Y	2.746	1.00
116_I	171_I	2.744	1.00
330_K	334_A	2.744	1.00
588_L	626_L	2.740	1.00
388_V	1302_D	2.703	1.00
1432_E	1468_K	2.695	1.00
808_T	823_Q	2.693	1.00
116_I	123_V	2.676	1.00
41_Q	381_Y	2.676	1.00
599_D	603_Q	2.669	1.00
818_Y	822_K	2.638	1.00
1258_G	1292_P	2.629	0.99
1276_K	1298_Y	2.620	0.99
1334_I	1353_A	2.612	0.99
826_K	830_E	2.592	0.99
70_Q	222_A	2.586	0.99
1408_E	1465_K	2.580	0.99
1279_F	1287_F	2.574	0.99
882_L	1146_I	2.573	0.99
1300_D	1319_K	2.564	0.99
1025_A	1032_I	2.549	0.99
1227_L	1256_I	2.547	0.99
467_A	628_P	2.537	0.99
475_I	685_T	2.527	0.99
1327_A	1330_D	2.526	0.99
748_Y	761_L	2.525	0.99
1406_L	1465_K	2.524	0.99
701_E	705_K	2.522	0.99
1375_G	1394_F	2.493	0.99
585_I	615_L	2.485	0.99
1235_E	1264_R	2.482	0.99
1433_I	1463_V	2.473	0.99
1260_E	1264_R	2.471	0.99
818_Y	1159_E	2.466	0.99
1296_T	1317_I	2.458	0.99
930_S	1262_S	2.441	0.99
573_K	584_K	2.416	0.99
160_D	163_S	2.414	0.99
1427_L	1463_V	2.408	0.99
465_Q	685_T	2.405	0.99
1409_D	1412_A	2.385	0.99
1001_A	1259_S	2.380	0.99
1095_L	1172_M	2.377	0.99
1243_S	1278_H	2.365	0.99
300_F	313_T	2.363	0.99
1298_Y	1319_K	2.351	0.99
1172_M	1178_V	2.350	0.99
667_A	714_V	2.330	0.99
507_Q	511_N	2.327	0.99
857_A	1151_L	2.324	0.99
939_L	1007_I	2.306	0.99
1122_D	1132_N	2.299	0.99
1307_V	1316_I	2.289	0.99
457_Q	460_D	2.266	0.98
330_K	436_Q	2.260	0.98
1025_A	1076_V	2.260	0.98
1334_I	1338_A	2.258	0.98
1453_E	1457_D	2.254	0.98
601_F	637_A	2.251	0.98
1437_K	1441_E	2.239	0.98
825_T	1156_E	2.239	0.98
1169_F	1173_I	2.238	0.98
1161_M	1169_F	2.232	0.98
996_H	1220_S	2.228	0.98
223_F	414_L	2.223	0.98
1300_D	1322_E	2.208	0.98
842_F	1164_L	2.206	0.98
889_L	1147_V	2.202	0.98
1160_Y	1163_A	2.191	0.98
378_K	1325_N	2.190	0.98
524_P	943_M	2.183	0.98
73_D	91_Y	2.175	0.98
1234_I	1264_R	2.168	0.98
605_E	647_L	2.166	0.98
587_V	617_L	2.161	0.98
614_L	654_I	2.149	0.98
1315_K	1346_E	2.134	0.98
876_K	880_E	2.131	0.98
1080_T	1084_L	2.120	0.98
844_G	1163_A	2.118	0.98
1376_C	1394_F	2.114	0.98
247_L	296_L	2.113	0.98
133_V	144_C	2.112	0.98
888_R	912_D	2.108	0.97
1288_G	1316_I	2.105	0.97
767_E	1190_K	2.103	0.97
1161_M	1168_T	2.096	0.97
717_V	1047_T	2.094	0.97
1273_D	1315_K	2.093	0.97
351_A	372_A	2.093	0.97
378_K	399_L	2.078	0.97
400_Y	421_S	2.068	0.97
1385_V	1439_M	2.062	0.97
1273_D	1296_T	2.062	0.97
845_N	849_L	2.052	0.97
859_S	862_K	2.039	0.97
396_E	1323_G	2.033	0.97
527_A	719_S	2.032	0.97
636_S	748_Y	2.027	0.97
605_E	641_H	2.013	0.97
1423_L	1472_K	1.994	0.96
1315_K	1446_Y	1.991	0.96
846_R	1166_F	1.989	0.96
1175_R	1178_V	1.983	0.96
1090_V	1153_I	1.979	0.96
888_R	910_N	1.978	0.96
74_A	218_A	1.970	0.96
1455_L	1462_S	1.967	0.96
632_L	668_A	1.964	0.96
90_R	154_A	1.963	0.96
1368_V	1371_I	1.956	0.96
105_R	146_F	1.952	0.96
930_S	1001_A	1.944	0.96
1417_C	1424_F	1.943	0.96
1413_F	1417_C	1.942	0.96
766_E	770_R	1.927	0.96
1231_Q	1235_E	1.913	0.96
880_E	914_R	1.913	0.96
888_R	913_D	1.908	0.95
557_I	572_L	1.906	0.95
94_G	150_V	1.898	0.95
113_N	126_W	1.894	0.95
606_K	610_Q	1.884	0.95
354_F	361_G	1.880	0.95
48_Q	392_E	1.876	0.95
802_N	805_T	1.872	0.95
934_V	1263_K	1.866	0.95
1348_Y	1439_M	1.863	0.95
841_A	1182_S	1.858	0.95
122_V	153_G	1.847	0.95
589_F	769_Q	1.830	0.94
884_I	888_R	1.818	0.94
644_R	750_S	1.808	0.94
1288_G	1297_L	1.808	0.94
1206_V	1210_Q	1.802	0.94
75_F	219_F	1.798	0.94
1259_S	1263_K	1.793	0.94
1063_A	1078_L	1.789	0.94
78_K	216_D	1.789	0.94
858_E	1151_L	1.788	0.94
1176_T	1200_L	1.784	0.93
113_N	117_E	1.776	0.93
1116_M	1125_P	1.771	0.93
538_T	730_R	1.766	0.93
312_H	339_H	1.762	0.93
573_K	616_I	1.750	0.93
1390_V	1413_F	1.750	0.93
1278_H	1300_D	1.731	0.92
212_S	215_Q	1.717	0.92
437_K	441_E	1.713	0.92
1220_S	1250_N	1.712	0.92
375_Y	388_V	1.710	0.92
1220_S	1223_I	1.704	0.92
1328_S	1450_Q	1.702	0.92
1339_F	1347_A	1.701	0.92
1287_F	1299_L	1.697	0.92
1169_F	1172_M	1.692	0.91
931_H	1267_E	1.690	0.91
602_T	641_H	1.689	0.91
563_V	677_I	1.688	0.91
278_D	281_K	1.688	0.91
871_F	967_V	1.687	0.91
888_R	1147_V	1.684	0.91
915_R	935_N	1.678	0.91
315_M	429_I	1.667	0.91
1149_Y	1153_I	1.667	0.91
1342_A	1364_V	1.661	0.91
1017_V	1063_A	1.660	0.91
421_S	424_E	1.658	0.91
1408_E	1451_K	1.658	0.91
138_T	142_K	1.654	0.91
1425_E	1475_K	1.654	0.91
1339_F	1364_V	1.653	0.90
840_F	1199_L	1.645	0.90
586_D	621_K	1.644	0.90
871_F	963_W	1.639	0.90
1365_N	1439_M	1.638	0.90
740_I	744_V	1.633	0.90
1350_N	1451_K	1.632	0.90
436_Q	440_E	1.632	0.90
688_Q	692_E	1.632	0.90
154_A	164_F	1.628	0.90
1144_D	1147_V	1.624	0.90
821_F	1149_Y	1.623	0.90
260_I	295_I	1.620	0.90
1329_D	1350_N	1.617	0.89
1418_N	1422_I	1.615	0.89
31_K	417_G	1.609	0.89
311_A	359_Q	1.608	0.89
1257_T	1295_M	1.605	0.89
849_L	1167_K	1.603	0.89
549_P	553_N	1.603	0.89
667_A	717_V	1.602	0.89
588_L	621_K	1.598	0.89
1385_V	1440_L	1.593	0.89
1339_F	1358_A	1.589	0.89
376_V	419_I	1.586	0.89
1091_V	1172_M	1.586	0.89
1348_Y	1446_Y	1.586	0.89
1454_D	1458_Q	1.583	0.88
1338_A	1353_A	1.582	0.88
112_I	150_V	1.581	0.88
996_H	1252_V	1.576	0.88
1157_V	1161_M	1.575	0.88
1003_R	1259_S	1.573	0.88
1001_A	1255_T	1.563	0.88
1276_K	1296_T	1.561	0.88
1436_I	1463_V	1.551	0.87
1074_D	1210_Q	1.547	0.87
26_L	360_I	1.537	0.87
718_M	726_V	1.534	0.87
1441_E	1445_A	1.531	0.87
1319_K	1322_E	1.525	0.86
1226_I	1277_L	1.525	0.86
109_E	128_T	1.523	0.86
1224_T	1250_N	1.522	0.86
508_S	771_R	1.522	0.86
931_H	935_N	1.521	0.86
76_F	93_V	1.512	0.86
115_L	174_Q	1.512	0.86
737_A	745_I	1.508	0.86
1458_Q	1462_S	1.507	0.86
1230_V	1277_L	1.507	0.86
409_M	425_V	1.505	0.86
133_V	210_F	1.499	0.86
382_I	410_L	1.499	0.86
845_N	848_P	1.497	0.85
858_E	861_V	1.494	0.85
374_Y	400_Y	1.493	0.85
92_G	191_L	1.493	0.85
1272_E	1315_K	1.492	0.85
561_T	711_T	1.492	0.85
1307_V	1318_V	1.489	0.85
744_V	761_L	1.488	0.85
873_S	1104_A	1.488	0.85
846_R	1175_R	1.487	0.85
744_V	764_I	1.486	0.85
1259_S	1262_S	1.486	0.85
861_V	1151_L	1.485	0.85
910_N	913_D	1.482	0.85
96_V	188_F	1.470	0.84
314_A	317_L	1.467	0.84
846_R	1178_V	1.467	0.84
531_Q	712_E	1.460	0.84
1157_V	1169_F	1.452	0.84
825_T	829_D	1.449	0.83
32_G	414_L	1.446	0.83
1329_D	1454_D	1.445	0.83
1291_V	1314_G	1.443	0.83
316_M	339_H	1.442	0.83
1451_K	1454_D	1.442	0.83
29_H	380_D	1.440	0.83
492_S	1120_H	1.439	0.83
1427_L	1433_I	1.435	0.83
601_F	747_R	1.434	0.83
1168_T	1172_M	1.430	0.83
358_K	415_E	1.427	0.83
1261_I	1275_I	1.425	0.82
1246_I	1253_A	1.424	0.82
536_T	715_V	1.420	0.82
58_D	139_V	1.419	0.82
95_M	149_Q	1.417	0.82
620_K	656_E	1.415	0.82
161_N	193_S	1.410	0.82
1297_L	1316_I	1.410	0.82
1128_V	1139_F	1.410	0.82
1426_S	1467_V	1.405	0.82
42_G	224_A	1.401	0.81
479_L	682_A	1.400	0.81
467_A	622_M	1.400	0.81
394_E	397_N	1.398	0.81
736_E	755_Q	1.397	0.81
1298_Y	1446_Y	1.396	0.81
662_E	665_H	1.394	0.81
464_R	684_A	1.393	0.81
1339_F	1366_V	1.391	0.81
36_H	40_K	1.389	0.81
123_V	150_V	1.388	0.81
1253_A	1279_F	1.388	0.81
1156_E	1159_E	1.387	0.81
683_Y	707_G	1.375	0.80
584_K	618_S	1.375	0.80
1142_D	1145_H	1.373	0.80
152_I	171_I	1.373	0.80
842_F	1091_V	1.372	0.80
763_T	1193_Q	1.370	0.80
1242_I	1279_F	1.369	0.80
1242_I	1277_L	1.368	0.80
572_L	614_L	1.368	0.80
83_I	125_G	1.365	0.80
1084_L	1101_F	1.364	0.80
1262_S	1292_P	1.362	0.79
759_I	763_T	1.361	0.79
1383_S	1439_M	1.360	0.79
842_F	1160_Y	1.360	0.79
741_S	757_G	1.358	0.79
765_A	769_Q	1.358	0.79
741_S	760_D	1.358	0.79
1088_R	1092_M	1.355	0.79
395_Q	1323_G	1.348	0.79
262_W	731_G	1.345	0.79
865_K	1079_E	1.345	0.79
853_E	1171_E	1.343	0.78
1074_D	1211_S	1.343	0.78
99_S	108_I	1.340	0.78
331_E	431_T	1.339	0.78
1317_I	1446_Y	1.339	0.78
1074_D	1206_V	1.338	0.78
1094_A	1173_I	1.335	0.78
119_E	174_Q	1.333	0.78
829_D	1160_Y	1.327	0.78
1233_A	1274_T	1.327	0.78
385_S	390_V	1.325	0.77
1442_R	1446_Y	1.324	0.77
118_Q	174_Q	1.320	0.77
767_E	1189_W	1.318	0.77
816_N	1148_N	1.318	0.77
1094_A	1169_F	1.318	0.77
1383_S	1402_I	1.315	0.77
1308_G	1316_I	1.315	0.77
905_F	935_N	1.314	0.77
1080_T	1101_F	1.311	0.77
132_N	212_S	1.310	0.77
427_T	431_T	1.310	0.77
635_V	655_V	1.308	0.77
1209_F	1212_P	1.308	0.77
1440_L	1455_L	1.307	0.77
938_E	1006_R	1.307	0.77
818_Y	1155_E	1.305	0.76
686_Y	702_A	1.304	0.76
1155_E	1159_E	1.302	0.76
1389_D	1409_D	1.300	0.76
95_M	147_V	1.299	0.76
1226_I	1244_I	1.294	0.76
1440_L	1444_T	1.294	0.76
479_L	686_Y	1.291	0.76
86_P	89_E	1.290	0.76
1258_G	1295_M	1.289	0.75
441_E	551_E	1.288	0.75
1246_I	1283_A	1.287	0.75
802_N	827_A	1.286	0.75
1241_D	1276_K	1.284	0.75
432_E	549_P	1.283	0.75
601_F	638_L	1.282	0.75
1255_T	1259_S	1.282	0.75
1223_I	1256_I	1.279	0.75
483_I	705_K	1.278	0.75
26_L	384_F	1.278	0.75
1095_L	1166_F	1.274	0.75
1077_V	1209_F	1.269	0.74
110_K	113_N	1.267	0.74
1071_G	1205_G	1.265	0.74
25_G	45_M	1.262	0.74
1006_R	1077_V	1.261	0.74
115_L	118_Q	1.260	0.74
996_H	1250_N	1.258	0.74
116_I	152_I	1.257	0.74
1462_S	1465_K	1.250	0.73
290_G	298_N	1.250	0.73
740_I	745_I	1.249	0.73
503_S	797_E	1.249	0.73
299_A	317_L	1.238	0.72
851_L	1155_E	1.238	0.72
1234_I	1261_I	1.236	0.72
1366_V	1384_V	1.236	0.72
147_V	210_F	1.235	0.72
131_V	136_I	1.231	0.72
590_S	626_L	1.231	0.72
1408_E	1462_S	1.229	0.72
38_I	381_Y	1.224	0.72
1334_I	1349_I	1.223	0.72
884_I	912_D	1.222	0.71
690_I	699_Y	1.221	0.71
379_D	397_N	1.217	0.71
71_I	93_V	1.214	0.71
1202_Q	1207_R	1.214	0.71
800_A	835_F	1.213	0.71
895_S	937_D	1.211	0.71
1425_E	1468_K	1.211	0.71
1257_T	1275_I	1.207	0.70
544_G	553_N	1.207	0.70
1214_N	1217_I	1.203	0.70
848_P	1163_A	1.202	0.70
660_A	666_F	1.202	0.70
930_S	1292_P	1.201	0.70
197_V	242_H	1.201	0.70
1329_D	1451_K	1.200	0.70
92_G	164_F	1.199	0.70
1161_M	1166_F	1.199	0.70
69_V	196_I	1.198	0.70
422_D	426_K	1.196	0.70
106_K	110_K	1.194	0.70
737_A	752_T	1.193	0.70
24_I	54_G	1.191	0.69
840_F	1200_L	1.189	0.69
132_N	209_A	1.189	0.69
641_H	645_K	1.187	0.69
608_I	651_V	1.186	0.69
594_E	598_K	1.182	0.69
1346_E	1446_Y	1.180	0.69
300_F	314_A	1.180	0.69
587_V	634_A	1.179	0.69
524_P	944_A	1.179	0.69
329_S	334_A	1.178	0.69
600_M	615_L	1.178	0.69
71_I	219_F	1.177	0.69
1424_F	1469_V	1.176	0.68
598_K	747_R	1.165	0.68
28_A	382_I	1.165	0.68
605_E	609_S	1.160	0.67
1028_T	1216_K	1.159	0.67
269_Q	650_K	1.155	0.67
825_T	1086_T	1.155	0.67
596_G	603_Q	1.152	0.67
1184_R	1193_Q	1.148	0.67
1241_D	1278_H	1.147	0.66
905_F	912_D	1.146	0.66
1034_I	1063_A	1.144	0.66
61_T	140_A	1.142	0.66
1227_L	1257_T	1.141	0.66
74_A	78_K	1.140	0.66
654_I	676_A	1.140	0.66
1093_A	1101_F	1.139	0.66
382_I	412_I	1.138	0.66
416_E	428_Q	1.136	0.66
54_G	1028_T	1.135	0.66
1228_P	1231_Q	1.134	0.66
884_I	1143_P	1.133	0.66
636_S	761_L	1.133	0.66
1169_F	1178_V	1.130	0.65
80_C	83_I	1.129	0.65
600_M	603_Q	1.129	0.65
1260_E	1263_K	1.128	0.65
119_E	171_I	1.117	0.64
267_E	646_G	1.117	0.64
600_M	629_I	1.113	0.64
708_K	712_E	1.113	0.64
940_Q	1079_E	1.112	0.64
1240_A	1275_I	1.111	0.64
1440_L	1452_A	1.109	0.64
789_D	1050_K	1.109	0.64
745_I	754_S	1.108	0.64
1477_M	1481_I	1.107	0.64
80_C	125_G	1.106	0.64
1320_S	1350_N	1.103	0.63
1358_A	1366_V	1.103	0.63
564_L	676_A	1.103	0.63
434_P	438_W	1.101	0.63
590_S	625_R	1.098	0.63
491_G	1046_K	1.098	0.63
1328_S	1350_N	1.098	0.63
26_L	382_I	1.097	0.63
1418_N	1421_M	1.096	0.63
850_K	853_E	1.096	0.63
1339_F	1349_I	1.096	0.63
1434_Q	1438_A	1.095	0.63
823_Q	826_K	1.094	0.63
376_V	1007_I	1.093	0.63
930_S	1259_S	1.091	0.63
1399_S	1421_M	1.091	0.63
871_F	876_K	1.091	0.63
596_G	599_D	1.089	0.62
331_E	436_Q	1.089	0.62
223_F	360_I	1.088	0.62
1229_A	1242_I	1.088	0.62
1436_I	1466_F	1.088	0.62
1410_V	1413_F	1.086	0.62
1278_H	1319_K	1.086	0.62
1243_S	1280_T	1.084	0.62
871_F	964_V	1.084	0.62
1232_E	1238_K	1.083	0.62
1373_D	1392_K	1.083	0.62
376_V	382_I	1.079	0.62
1003_R	1256_I	1.079	0.62
527_A	534_T	1.078	0.62
478_Y	489_P	1.077	0.62
1261_I	1291_V	1.077	0.62
116_I	121_Q	1.077	0.62
79_E	218_A	1.076	0.61
640_Q	643_I	1.075	0.61
798_H	834_G	1.072	0.61
849_L	1162_A	1.072	0.61
1410_V	1465_K	1.072	0.61
1406_L	1455_L	1.070	0.61
597_L	637_A	1.070	0.61
867_G	1104_A	1.069	0.61
433_Y	549_P	1.067	0.61
831_E	838_N	1.066	0.61
821_F	829_D	1.065	0.61
821_F	1153_I	1.064	0.61
930_S	1312_S	1.063	0.60
1327_A	1450_Q	1.062	0.60
1318_V	1334_I	1.060	0.60
656_E	678_N	1.059	0.60
1376_C	1384_V	1.059	0.60
230_F	1027_A	1.059	0.60
583_Q	610_Q	1.058	0.60
1291_V	1297_L	1.056	0.60
1412_A	1416_K	1.056	0.60
1001_A	1262_S	1.054	0.60
1303_S	1307_V	1.053	0.60
309_K	312_H	1.052	0.60
1008_S	1031_V	1.052	0.60
395_Q	398_V	1.051	0.60
583_Q	607_A	1.051	0.60
286_L	299_A	1.049	0.59
1455_L	1464_K	1.047	0.59
1438_A	1441_E	1.047	0.59
743_D	760_D	1.043	0.59
458_F	688_Q	1.042	0.59
30_L	34_Q	1.041	0.59
395_Q	1326_S	1.038	0.59
1166_F	1175_R	1.037	0.59
1095_L	1176_T	1.036	0.58
1232_E	1236_S	1.036	0.58
889_L	1151_L	1.034	0.58
331_E	427_T	1.033	0.58
1213_Q	1217_I	1.032	0.58
1404_Y	1435_Q	1.032	0.58
744_V	760_D	1.031	0.58
858_E	862_K	1.030	0.58
416_E	424_E	1.028	0.58
814_R	1145_H	1.028	0.58
87_E	90_R	1.025	0.58
835_F	838_N	1.025	0.58
536_T	714_V	1.023	0.57
1003_R	1263_K	1.021	0.57
122_V	155_S	1.021	0.57
113_N	150_V	1.020	0.57
47_C	208_D	1.017	0.57
929_K	1343_T	1.017	0.57
309_K	429_I	1.015	0.57
1390_V	1405_V	1.014	0.57
244_N	895_S	1.013	0.57
510_F	659_E	1.012	0.57
905_F	931_H	1.012	0.57
1033_V	1102_G	1.011	0.57
808_T	827_A	1.008	0.56
264_R	267_E	1.008	0.56
1413_F	1469_V	1.005	0.56
1013_S	1054_L	1.003	0.56
119_E	281_K	1.001	0.56
640_Q	750_S	1.001	0.56
884_I	910_N	1.001	0.56
1476_Q	1480_S	0.999	0.56
635_V	674_A	0.999	0.56
1394_F	1405_V	0.998	0.56
1474_Y	1478_L	0.997	0.56
892_K	917_A	0.997	0.56
1435_Q	1439_M	0.995	0.55
137_G	140_A	0.994	0.55
1394_F	1403_A	0.994	0.55
447_N	582_S	0.994	0.55
136_I	140_A	0.992	0.55
100_Q	144_C	0.991	0.55
1279_F	1297_L	0.991	0.55
1258_G	1291_V	0.989	0.55
882_L	1107_P	0.987	0.55
569_F	678_N	0.986	0.55
24_I	248_V	0.984	0.55
602_T	606_K	0.984	0.55
1061_A	1096_L	0.984	0.55
204_P	228_S	0.984	0.55
121_Q	155_S	0.984	0.55
247_L	293_S	0.984	0.55
538_T	726_V	0.984	0.55
170_V	281_K	0.982	0.54
270_F	285_I	0.981	0.54
1422_I	1469_V	0.980	0.54
403_R	1355_E	0.977	0.54
962_P	1258_G	0.976	0.54
1246_I	1287_F	0.975	0.54
868_A	894_N	0.975	0.54
1270_L	1274_T	0.974	0.54
1226_I	1257_T	0.974	0.54
740_I	764_I	0.973	0.54
627_T	768_A	0.972	0.54
76_F	380_D	0.969	0.53
687_K	699_Y	0.969	0.53
105_R	148_R	0.969	0.53
512_Y	1190_K	0.965	0.53
866_T	882_L	0.965	0.53
1237_G	1265_Y	0.965	0.53
1280_T	1300_D	0.964	0.53
376_V	400_Y	0.963	0.53
1000_N	1250_N	0.960	0.53
594_E	748_Y	0.959	0.53
1077_V	1170_D	0.958	0.53
1231_Q	1264_R	0.958	0.53
903_K	966_D	0.957	0.52
591_E	599_D	0.956	0.52
708_K	954_Q	0.956	0.52
850_K	1167_K	0.956	0.52
1175_R	1202_Q	0.955	0.52
993_Q	1252_V	0.955	0.52
1233_A	1240_A	0.955	0.52
85_L	89_E	0.954	0.52
165_E	193_S	0.953	0.52
401_K	1326_S	0.953	0.52
121_Q	152_I	0.951	0.52
1406_L	1464_K	0.951	0.52
756_L	836_L	0.951	0.52
244_N	293_S	0.950	0.52
1006_R	1031_V	0.948	0.52
1272_E	1293_K	0.947	0.52
534_T	961_Y	0.945	0.52
1405_V	1413_F	0.945	0.52
525_I	534_T	0.945	0.52
666_F	677_I	0.945	0.52
1375_G	1386_V	0.944	0.51
13_Y	18_E	0.944	0.51
1230_V	1242_I	0.944	0.51
1371_I	1390_V	0.944	0.51
895_S	913_D	0.944	0.51
1279_F	1283_A	0.944	0.51
500_A	511_N	0.943	0.51
361_G	411_L	0.943	0.51
133_V	141_Q	0.942	0.51
98_F	105_R	0.941	0.51
264_R	288_A	0.940	0.51
604_A	638_L	0.939	0.51
116_I	150_V	0.937	0.51
840_F	1181_A	0.935	0.51
1324_F	1328_S	0.934	0.51
1244_I	1279_F	0.933	0.51
1417_C	1422_I	0.933	0.51
263_M	299_A	0.933	0.51
1433_I	1459_W	0.932	0.51
961_Y	1122_D	0.931	0.50
663_V	717_V	0.929	0.50
697_I	702_A	0.928	0.50
608_I	638_L	0.928	0.50
801_F	1109_V	0.928	0.50
68_L	223_F	0.927	0.50
30_L	412_I	0.926	0.50
311_A	411_L	0.926	0.50
34_Q	88_K	0.925	0.50
930_S	1258_G	0.925	0.50
71_I	76_F	0.924	0.50
161_N	164_F	0.922	0.50
756_L	1032_I	0.921	0.50
527_A	1122_D	0.921	0.50
593_L	629_I	0.920	0.50
639_H	731_G	0.917	0.49
1390_V	1417_C	0.916	0.49
256_L	260_I	0.916	0.49
1444_T	1453_E	0.916	0.49
1111_L	1147_V	0.916	0.49
902_P	931_H	0.915	0.49
111_Q	115_L	0.914	0.49
766_E	773_R	0.914	0.49
1157_V	1160_Y	0.910	0.49
550_S	553_N	0.909	0.49
934_V	1001_A	0.909	0.49
1454_D	1457_D	0.909	0.49
655_V	674_A	0.909	0.49
121_Q	164_F	0.909	0.49
93_V	196_I	0.908	0.49
247_L	352_I	0.906	0.48
963_W	967_V	0.906	0.48
401_K	1302_D	0.906	0.48
592_D	765_A	0.906	0.48
461_L	465_Q	0.903	0.48
868_A	873_S	0.903	0.48
1424_F	1467_V	0.901	0.48
272_S	275_F	0.901	0.48
600_M	634_A	0.900	0.48
1423_L	1475_K	0.900	0.48
583_Q	603_Q	0.899	0.48
314_A	363_I	0.899	0.48
428_Q	432_E	0.899	0.48
808_T	820_L	0.898	0.48
28_A	414_L	0.897	0.48
495_N	1083_K	0.897	0.48
395_Q	1321_S	0.897	0.48
240_R	244_N	0.895	0.48
308_R	316_M	0.895	0.48
29_H	381_Y	0.894	0.48
1442_R	1445_A	0.894	0.48
478_Y	488_D	0.894	0.48
9_A	15_P	0.893	0.47
334_A	337_E	0.893	0.47
840_F	1179_L	0.891	0.47
569_F	584_K	0.890	0.47
938_E	1008_S	0.889	0.47
961_Y	1258_G	0.887	0.47
1157_V	1307_V	0.887	0.47
474_D	661_R	0.886	0.47
939_L	1005_A	0.886	0.47
829_D	1156_E	0.884	0.47
843_D	1177_D	0.884	0.47
1173_I	1208_T	0.884	0.47
92_G	168_L	0.883	0.47
9_A	14_R	0.883	0.47
1220_S	1256_I	0.882	0.47
375_Y	393_V	0.882	0.47
240_R	295_I	0.882	0.47
828_A	831_E	0.881	0.47
35_T	38_I	0.878	0.46
905_F	911_G	0.878	0.46
31_K	35_T	0.877	0.46
1219_Q	1223_I	0.875	0.46
128_T	146_F	0.875	0.46
328_M	332_K	0.874	0.46
1307_V	1349_I	0.874	0.46
845_N	1166_F	0.873	0.46
569_F	689_E	0.872	0.46
486_G	705_K	0.871	0.46
393_V	397_N	0.871	0.46
1332_V	1352_R	0.871	0.46
690_I	702_A	0.870	0.46
1410_V	1467_V	0.868	0.46
1094_A	1101_F	0.866	0.45
286_L	295_I	0.866	0.45
1296_T	1315_K	0.866	0.45
683_Y	703_V	0.865	0.45
317_L	592_D	0.864	0.45
478_Y	790_F	0.863	0.45
905_F	910_N	0.862	0.45
1440_L	1459_W	0.860	0.45
380_D	417_G	0.859	0.45
1375_G	1395_A	0.858	0.45
1214_N	1219_Q	0.858	0.45
109_E	126_W	0.858	0.45
50_D	204_P	0.858	0.45
1439_M	1443_H	0.858	0.45
1338_A	1349_I	0.858	0.45
304_V	313_T	0.857	0.45
467_A	772_H	0.857	0.45
514_K	1051_H	0.855	0.45
1015_A	1058_L	0.854	0.44
690_I	695_L	0.854	0.44
627_T	769_Q	0.853	0.44
921_I	998_L	0.853	0.44
248_V	1027_A	0.853	0.44
240_R	375_Y	0.853	0.44
798_H	832_R	0.852	0.44
844_G	1166_F	0.851	0.44
309_K	432_E	0.851	0.44
410_L	419_I	0.851	0.44
170_V	282_I	0.850	0.44
1311_L	1344_S	0.850	0.44
321_P	1079_E	0.850	0.44
1000_N	1220_S	0.849	0.44
1066_T	1069_L	0.849	0.44
592_D	595_R	0.849	0.44
1224_T	1228_P	0.848	0.44
1044_S	1052_T	0.847	0.44
1091_V	1169_F	0.847	0.44
818_Y	821_F	0.847	0.44
510_F	665_H	0.846	0.44
825_T	1153_I	0.846	0.44
460_D	464_R	0.845	0.44
39_V	69_V	0.845	0.44
1287_F	1316_I	0.845	0.44
413_D	416_E	0.845	0.44
905_F	1266_G	0.845	0.44
1385_V	1435_Q	0.845	0.44
813_C	1145_H	0.844	0.44
1434_Q	1441_E	0.844	0.44
675_D	730_R	0.844	0.44
845_N	1162_A	0.844	0.44
712_E	954_Q	0.843	0.44
824_Y	1153_I	0.842	0.44
323_T	537_M	0.841	0.43
41_Q	44_K	0.840	0.43
1316_I	1386_V	0.839	0.43
568_Q	571_A	0.839	0.43
235_F	1069_L	0.838	0.43
464_R	776_Y	0.838	0.43
235_F	1066_T	0.836	0.43
1013_S	1034_I	0.836	0.43
683_Y	686_Y	0.835	0.43
465_Q	784_L	0.834	0.43
1153_I	1156_E	0.834	0.43
96_V	175_A	0.834	0.43
1030_D	1215_H	0.834	0.43
343_M	924_G	0.833	0.43
114_A	118_Q	0.833	0.43
177_N	181_T	0.833	0.43
393_V	398_V	0.831	0.43
468_F	658_G	0.829	0.43
112_I	186_F	0.829	0.43
1166_F	1177_D	0.829	0.43
156_S	1453_E	0.829	0.43
56_G	59_P	0.827	0.42
1107_P	1151_L	0.826	0.42
1271_P	1274_T	0.825	0.42
58_D	372_A	0.824	0.42
29_H	35_T	0.823	0.42
375_Y	1302_D	0.823	0.42
1177_D	1202_Q	0.823	0.42
56_G	139_V	0.823	0.42
268_Q	646_G	0.821	0.42
659_E	938_E	0.821	0.42
1425_E	1470_I	0.820	0.42
813_C	821_F	0.818	0.42
665_H	1051_H	0.817	0.42
817_D	820_L	0.817	0.42
141_Q	144_C	0.817	0.42
818_Y	857_A	0.816	0.42
1003_R	1227_L	0.815	0.42
701_E	704_S	0.815	0.42
842_F	1166_F	0.815	0.42
846_R	1163_A	0.815	0.42
58_D	135_K	0.815	0.42
913_D	1147_V	0.813	0.41
1232_E	1235_E	0.812	0.41
1214_N	1218_D	0.810	0.41
302_F	321_P	0.810	0.41
488_D	1046_K	0.809	0.41
840_F	1194_L	0.809	0.41
1091_V	1094_A	0.808	0.41
746_D	750_S	0.808	0.41
667_A	677_I	0.808	0.41
1148_N	1152_F	0.808	0.41
1006_R	1033_V	0.808	0.41
1118_A	1123_T	0.806	0.41
37_D	921_I	0.806	0.41
931_H	1266_G	0.806	0.41
841_A	844_G	0.806	0.41
98_F	108_I	0.805	0.41
405_E	408_K	0.803	0.41
940_Q	1008_S	0.802	0.41
1084_L	1090_V	0.802	0.41
633_L	764_I	0.802	0.41
1111_L	1146_I	0.801	0.40
589_F	627_T	0.801	0.40
488_D	790_F	0.801	0.40
873_S	1129_A	0.800	0.40
540_L	1390_V	0.800	0.40
202_L	996_H	0.800	0.40
1276_K	1319_K	0.799	0.40
79_E	216_D	0.799	0.40
513_F	749_F	0.799	0.40
844_G	1180_H	0.799	0.40
537_M	558_K	0.798	0.40
55_Q	228_S	0.798	0.40
10_Q	1069_L	0.797	0.40
596_G	600_M	0.796	0.40
470_Y	682_A	0.795	0.40
1394_F	1469_V	0.795	0.40
1348_Y	1435_Q	0.795	0.40
798_H	802_N	0.795	0.40
1277_L	1297_L	0.794	0.40
905_F	1044_S	0.794	0.40
54_G	385_S	0.794	0.40
118_Q	1348_Y	0.794	0.40
1017_V	1080_T	0.793	0.40
1438_A	1442_R	0.793	0.40
474_D	613_S	0.793	0.40
664_H	668_A	0.790	0.40
483_I	486_G	0.788	0.40
873_S	1108_L	0.787	0.39
1268_E	1293_K	0.787	0.39
587_V	631_P	0.785	0.39
48_Q	391_I	0.785	0.39
147_V	189_A	0.784	0.39
1128_V	1140_M	0.784	0.39
128_T	131_V	0.784	0.39
143_S	201_L	0.783	0.39
677_I	717_V	0.783	0.39
402_N	405_E	0.783	0.39
831_E	835_F	0.782	0.39
871_F	1118_A	0.782	0.39
536_T	711_T	0.781	0.39
273_E	548_H	0.781	0.39
290_G	294_S	0.781	0.39
315_M	426_K	0.780	0.39
1068_M	1207_R	0.780	0.39
418_R	428_Q	0.779	0.39
323_T	727_Q	0.779	0.39
557_I	614_L	0.778	0.39
144_C	147_V	0.777	0.39
1413_F	1467_V	0.777	0.39
61_T	137_G	0.776	0.39
822_K	1163_A	0.776	0.39
1056_W	1093_A	0.776	0.39
563_V	660_A	0.775	0.39
1188_H	1191_A	0.775	0.39
58_D	140_A	0.775	0.39
1003_R	1223_I	0.775	0.39
109_E	1455_L	0.774	0.38
1368_V	1439_M	0.773	0.38
857_A	861_V	0.773	0.38
24_I	351_A	0.773	0.38
1385_V	1466_F	0.772	0.38
1166_F	1171_E	0.772	0.38
328_M	668_A	0.770	0.38
1236_S	1239_E	0.769	0.38
1047_T	1252_V	0.769	0.38
921_I	1007_I	0.769	0.38
378_K	400_Y	0.769	0.38
1441_E	1444_T	0.768	0.38
248_V	488_D	0.768	0.38
744_V	748_Y	0.767	0.38
538_T	675_D	0.766	0.38
111_Q	175_A	0.766	0.38
464_R	622_M	0.765	0.38
1282_S	1302_D	0.765	0.38
1090_V	1094_A	0.765	0.38
472_Y	476_Q	0.764	0.38
1402_I	1435_Q	0.764	0.38
658_G	1147_V	0.764	0.38
894_N	940_Q	0.764	0.38
1307_V	1334_I	0.763	0.38
244_N	248_V	0.762	0.38
876_K	963_W	0.762	0.38
704_S	708_K	0.761	0.38
532_L	1374_H	0.760	0.37
572_L	616_I	0.759	0.37
1273_D	1317_I	0.759	0.37
1440_L	1462_S	0.759	0.37
617_L	638_L	0.759	0.37
71_I	91_Y	0.759	0.37
310_P	1395_A	0.758	0.37
1087_G	1156_E	0.757	0.37
108_I	186_F	0.757	0.37
29_H	34_Q	0.757	0.37
488_D	1047_T	0.756	0.37
392_E	395_Q	0.756	0.37
841_A	1183_E	0.756	0.37
285_I	1412_A	0.755	0.37
840_F	1434_Q	0.754	0.37
1307_V	1347_A	0.754	0.37
248_V	1046_K	0.753	0.37
50_D	996_H	0.753	0.37
201_L	228_S	0.753	0.37
351_A	384_F	0.752	0.37
13_Y	1069_L	0.751	0.37
706_Y	710_I	0.751	0.37
10_Q	15_P	0.750	0.37
225_L	360_I	0.750	0.37
719_S	824_Y	0.750	0.37
19_H	1019_T	0.750	0.37
966_D	969_G	0.749	0.37
996_H	1000_N	0.748	0.37
1445_A	1457_D	0.748	0.37
92_G	616_I	0.747	0.37
823_Q	827_A	0.747	0.37
242_H	293_S	0.747	0.37
566_N	687_K	0.746	0.36
1176_T	1202_Q	0.746	0.36
891_G	937_D	0.744	0.36
1122_D	1258_G	0.744	0.36
556_R	675_D	0.744	0.36
1106_A	1149_Y	0.744	0.36
401_K	1333_I	0.743	0.36
296_L	352_I	0.742	0.36
30_L	376_V	0.741	0.36
1034_I	1250_N	0.741	0.36
868_A	940_Q	0.741	0.36
353_S	382_I	0.741	0.36
822_K	826_K	0.739	0.36
22_C	25_G	0.738	0.36
1022_A	1066_T	0.738	0.36
1110_V	1143_P	0.738	0.36
1352_R	1389_D	0.737	0.36
202_L	206_Q	0.737	0.36
540_L	652_S	0.737	0.36
492_S	957_G	0.737	0.36
600_M	1261_I	0.736	0.36
563_V	666_F	0.734	0.36
1337_V	1371_I	0.732	0.35
1079_E	1150_M	0.732	0.35
1239_E	1270_L	0.732	0.35
96_V	150_V	0.730	0.35
303_F	483_I	0.730	0.35
806_I	1111_L	0.730	0.35
892_K	1031_V	0.729	0.35
21_A	24_I	0.728	0.35
859_S	1168_T	0.728	0.35
1226_I	1253_A	0.727	0.35
759_I	764_I	0.727	0.35
332_K	427_T	0.727	0.35
483_I	686_Y	0.726	0.35
800_A	1085_M	0.726	0.35
1255_T	1287_F	0.726	0.35
111_Q	114_A	0.726	0.35
820_L	823_Q	0.726	0.35
534_T	1258_G	0.726	0.35
1196_L	1200_L	0.725	0.35
221_S	776_Y	0.724	0.35
152_I	164_F	0.724	0.35
670_I	1013_S	0.723	0.35
1091_V	1178_V	0.723	0.35
892_K	918_I	0.722	0.35
185_D	239_E	0.721	0.35
1436_I	1440_L	0.720	0.35
697_I	705_K	0.719	0.35
849_L	854_V	0.718	0.34
280_N	283_L	0.718	0.34
665_H	1290_F	0.716	0.34
1387_L	1440_L	0.716	0.34
490_L	943_M	0.716	0.34
1283_A	1303_S	0.715	0.34
1376_C	1386_V	0.715	0.34
97_F	147_V	0.714	0.34
1441_E	1456_L	0.714	0.34
54_G	240_R	0.714	0.34
296_L	300_F	0.714	0.34
257_R	516_L	0.712	0.34
395_Q	1234_I	0.712	0.34
287_N	290_G	0.712	0.34
935_N	1266_G	0.712	0.34
733_Q	750_S	0.711	0.34
510_F	668_A	0.711	0.34
667_A	954_Q	0.710	0.34
800_A	1038_D	0.709	0.34
42_G	384_F	0.709	0.34
1014_K	1020_I	0.708	0.34
756_L	1194_L	0.708	0.34
24_I	1083_K	0.707	0.34
534_T	1292_P	0.706	0.34
570_Y	573_K	0.706	0.34
488_D	705_K	0.706	0.34
507_Q	789_D	0.705	0.34
124_L	153_G	0.705	0.34
174_Q	281_K	0.704	0.34
791_Q	1118_A	0.704	0.34
1450_Q	1454_D	0.704	0.34
136_I	683_Y	0.703	0.33
329_S	332_K	0.702	0.33
921_I	1410_V	0.702	0.33
622_M	776_Y	0.702	0.33
1414_K	1424_F	0.701	0.33
225_L	353_S	0.701	0.33
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536_T	1079_E	0.700	0.33
1293_K	1312_S	0.700	0.33
1273_D	1446_Y	0.700	0.33
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1235_E	1238_K	0.699	0.33
630_P	1354_G	0.699	0.33
1256_I	1259_S	0.698	0.33
1128_V	1152_F	0.698	0.33
30_L	414_L	0.697	0.33
242_H	248_V	0.697	0.33
842_F	1088_R	0.697	0.33
1433_I	1460_E	0.696	0.33
133_V	136_I	0.696	0.33
228_S	240_R	0.696	0.33
147_V	211_Y	0.696	0.33
678_N	683_Y	0.695	0.33
841_A	1163_A	0.695	0.33
1276_K	1300_D	0.695	0.33
616_I	1371_I	0.695	0.33
597_L	747_R	0.695	0.33
456_E	460_D	0.694	0.33
884_I	913_D	0.694	0.33
1462_S	1466_F	0.693	0.33
829_D	1358_A	0.693	0.33
631_P	657_S	0.693	0.33
69_V	75_F	0.693	0.33
205_E	211_Y	0.693	0.33
1440_L	1463_V	0.692	0.33
801_F	824_Y	0.692	0.33
247_L	314_A	0.692	0.33
329_S	427_T	0.692	0.33
1079_E	1083_K	0.691	0.33
397_N	1325_N	0.691	0.33
57_S	1246_I	0.691	0.33
1000_N	1217_I	0.690	0.33
1025_A	1078_L	0.690	0.33
1231_Q	1236_S	0.690	0.33
388_V	401_K	0.690	0.33
640_Q	672_Y	0.690	0.33
1228_P	1232_E	0.689	0.32
508_S	1035_S	0.689	0.32
39_V	219_F	0.689	0.32
1436_I	1439_M	0.689	0.32
58_D	61_T	0.689	0.32
910_N	935_N	0.688	0.32
1168_T	1173_I	0.688	0.32
588_L	627_T	0.688	0.32
591_E	765_A	0.687	0.32
1317_I	1444_T	0.687	0.32
636_S	744_V	0.687	0.32
761_L	764_I	0.687	0.32
270_F	287_N	0.686	0.32
760_D	830_E	0.686	0.32
480_I	484_K	0.685	0.32
582_S	616_I	0.685	0.32
237_T	663_V	0.685	0.32
1074_D	1101_F	0.685	0.32
587_V	600_M	0.684	0.32
858_E	889_L	0.684	0.32
262_W	639_H	0.683	0.32
1227_L	1230_V	0.683	0.32
625_R	772_H	0.682	0.32
844_G	1178_V	0.682	0.32
772_H	776_Y	0.682	0.32
176_E	186_F	0.682	0.32
216_D	333_R	0.681	0.32
840_F	1180_H	0.681	0.32
261_N	732_A	0.680	0.32
1079_E	1116_M	0.679	0.32
1004_D	1259_S	0.679	0.32
54_G	1132_N	0.679	0.32
805_T	828_A	0.679	0.32
240_R	536_T	0.678	0.32
1346_E	1443_H	0.678	0.32
996_H	1215_H	0.678	0.32
383_I	851_L	0.678	0.32
135_K	209_A	0.677	0.32
631_P	659_E	0.677	0.32
45_M	49_L	0.676	0.32
266_R	661_R	0.675	0.32
119_E	1203_P	0.675	0.32
246_Y	352_I	0.675	0.32
1216_K	1219_Q	0.674	0.31
802_N	905_F	0.674	0.31
855_E	863_R	0.674	0.31
302_F	410_L	0.673	0.31
1180_H	1184_R	0.673	0.31
34_Q	414_L	0.672	0.31
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105_R	109_E	0.672	0.31
92_G	152_I	0.671	0.31
902_P	969_G	0.671	0.31
589_F	1172_M	0.671	0.31
1224_T	1229_A	0.671	0.31
54_G	212_S	0.671	0.31
744_V	759_I	0.671	0.31
162_L	165_E	0.670	0.31
767_E	1051_H	0.669	0.31
881_A	1128_V	0.668	0.31
248_V	527_A	0.667	0.31
320_E	336_Y	0.667	0.31
858_E	1155_E	0.667	0.31
588_L	623_N	0.667	0.31
228_S	963_W	0.667	0.31
155_S	171_I	0.666	0.31
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353_S	419_I	0.666	0.31
1254_G	1297_L	0.666	0.31
1412_A	1465_K	0.665	0.31
877_E	1136_R	0.665	0.31
121_Q	154_A	0.665	0.31
891_G	1153_I	0.665	0.31
1454_D	1462_S	0.665	0.31
1220_S	1252_V	0.665	0.31
1226_I	1230_V	0.664	0.31
939_L	1093_A	0.664	0.31
1328_S	1451_K	0.664	0.31
585_I	1317_I	0.664	0.31
1334_I	1347_A	0.663	0.31
974_V	1126_V	0.663	0.31
1000_N	1221_L	0.663	0.31
315_M	335_F	0.663	0.31
28_A	340_S	0.662	0.31
1226_I	1229_A	0.662	0.31
240_R	1079_E	0.662	0.31
551_E	554_V	0.662	0.31
1223_I	1227_L	0.662	0.31
658_G	972_P	0.662	0.31
1220_S	1249_T	0.661	0.31
186_F	1161_M	0.661	0.31
320_E	426_K	0.660	0.31
753_A	1015_A	0.660	0.31
828_A	1085_M	0.659	0.30
704_S	1330_D	0.659	0.30
1414_K	1419_L	0.659	0.30
287_N	298_N	0.658	0.30
745_I	939_L	0.658	0.30
1161_M	1178_V	0.658	0.30
869_M	1047_T	0.658	0.30
1365_N	1383_S	0.658	0.30
1147_V	1151_L	0.658	0.30
445_Q	448_P	0.658	0.30
160_D	164_F	0.658	0.30
82_N	87_E	0.658	0.30
939_L	966_D	0.658	0.30
110_K	114_A	0.658	0.30
121_Q	167_K	0.657	0.30
147_V	352_I	0.657	0.30
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1290_F	1343_T	0.657	0.30
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1157_V	1172_M	0.656	0.30
774_E	785_E	0.656	0.30
1330_D	1352_R	0.656	0.30
167_K	170_V	0.655	0.30
954_Q	1044_S	0.654	0.30
1076_V	1224_T	0.654	0.30
65_A	204_P	0.654	0.30
801_F	1106_A	0.654	0.30
1083_K	1477_M	0.653	0.30
961_Y	1292_P	0.653	0.30
283_L	646_G	0.652	0.30
947_A	955_L	0.652	0.30
745_I	752_T	0.652	0.30
492_S	958_N	0.652	0.30
337_E	340_S	0.651	0.30
1122_D	1292_P	0.651	0.30
116_I	120_G	0.650	0.30
1151_L	1155_E	0.650	0.30
1234_I	1295_M	0.650	0.30
1226_I	1242_I	0.649	0.30
495_N	1037_Y	0.649	0.30
488_D	667_A	0.649	0.30
831_E	1109_V	0.648	0.30
1045_P	1048_S	0.648	0.30
999_K	1213_Q	0.648	0.30
394_E	398_V	0.647	0.30
662_E	790_F	0.647	0.30
1230_V	1257_T	0.647	0.30
1245_E	1280_T	0.646	0.30
516_L	736_E	0.646	0.30
587_V	655_V	0.646	0.30
1266_G	1269_G	0.646	0.30
293_S	402_N	0.646	0.30
688_Q	691_D	0.644	0.30
242_H	943_M	0.644	0.30
341_S	556_R	0.644	0.30
35_T	1324_F	0.644	0.30
861_V	868_A	0.644	0.30
865_K	1150_M	0.644	0.30
41_Q	397_N	0.643	0.29
381_Y	397_N	0.643	0.29
954_Q	1354_G	0.643	0.29
565_S	568_Q	0.642	0.29
492_S	1418_N	0.642	0.29
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512_Y	767_E	0.641	0.29
318_I	384_F	0.641	0.29
49_L	1326_S	0.641	0.29
1197_S	1201_Y	0.641	0.29
272_S	547_L	0.640	0.29
106_K	109_E	0.640	0.29
42_G	360_I	0.640	0.29
733_Q	752_T	0.639	0.29
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1091_V	1161_M	0.639	0.29
719_S	901_D	0.639	0.29
534_T	865_K	0.639	0.29
483_I	775_A	0.639	0.29
408_K	422_D	0.638	0.29
961_Y	1132_N	0.638	0.29
29_H	222_A	0.638	0.29
479_L	685_T	0.637	0.29
717_V	1261_I	0.637	0.29
279_L	546_L	0.636	0.29
509_L	748_Y	0.636	0.29
962_P	1118_A	0.636	0.29
335_F	339_H	0.636	0.29
548_H	1007_I	0.636	0.29
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1255_T	1316_I	0.635	0.29
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904_R	916_S	0.635	0.29
1455_L	1466_F	0.635	0.29
597_L	902_P	0.635	0.29
416_E	420_I	0.635	0.29
866_T	891_G	0.635	0.29
536_T	1258_G	0.634	0.29
1334_I	1339_F	0.634	0.29
475_I	689_E	0.634	0.29
788_S	1014_K	0.634	0.29
465_Q	787_G	0.633	0.29
1109_V	1260_E	0.633	0.29
282_I	285_I	0.633	0.29
125_G	151_F	0.633	0.29
822_K	825_T	0.633	0.29
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715_V	1079_E	0.631	0.29
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1229_A	1243_S	0.631	0.29
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514_K	734_I	0.631	0.29
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275_F	1080_T	0.629	0.29
508_S	511_N	0.629	0.29
414_L	1121_L	0.628	0.28
321_P	1046_K	0.628	0.28
132_N	459_S	0.628	0.28
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34_Q	220_V	0.627	0.28
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410_L	416_E	0.627	0.28
24_I	352_I	0.627	0.28
45_M	391_I	0.626	0.28
901_D	966_D	0.626	0.28
1298_Y	1317_I	0.626	0.28
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375_Y	380_D	0.625	0.28
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929_K	1344_S	0.624	0.28
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24_I	256_L	0.622	0.28
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302_F	547_L	0.622	0.28
555_R	579_D	0.622	0.28
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787_G	954_Q	0.622	0.28
540_L	572_L	0.621	0.28
564_L	1194_L	0.621	0.28
196_I	219_F	0.621	0.28
924_G	1126_V	0.621	0.28
550_S	1469_V	0.620	0.28
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401_K	1320_S	0.619	0.28
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242_H	1107_P	0.618	0.28
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798_H	831_E	0.618	0.28
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1326_S	1331_N	0.615	0.28
1475_K	1479_A	0.615	0.28
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1020_I	1054_L	0.615	0.28
931_H	1262_S	0.614	0.28
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325_N	478_Y	0.614	0.28
865_K	892_K	0.614	0.28
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1470_I	1473_N	0.613	0.28
163_S	166_R	0.613	0.28
14_R	131_V	0.613	0.28
677_I	826_K	0.613	0.28
369_L	525_I	0.613	0.28
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1390_V	1407_T	0.612	0.27
1110_V	1145_H	0.612	0.27
689_E	1416_K	0.611	0.27
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811_W	1110_V	0.611	0.27
1064_H	1208_T	0.611	0.27
670_I	677_I	0.611	0.27
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1320_S	1326_S	0.610	0.27
75_F	79_E	0.610	0.27
557_I	1153_I	0.610	0.27
1000_N	1256_I	0.610	0.27
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534_T	962_P	0.609	0.27
139_V	142_K	0.609	0.27
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1408_E	1464_K	0.609	0.27
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1101_F	1169_F	0.608	0.27
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144_C	201_L	0.607	0.27
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423_E	444_V	0.606	0.27
581_K	612_V	0.606	0.27
27_Y	381_Y	0.605	0.27
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258_G	732_A	0.605	0.27
544_G	550_S	0.605	0.27
600_M	638_L	0.605	0.27
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124_L	585_I	0.605	0.27
527_A	1376_C	0.604	0.27
962_P	1292_P	0.604	0.27
236_P	982_H	0.604	0.27
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1101_F	1170_D	0.602	0.27
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312_H	316_M	0.598	0.27
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1181_A	1192_S	0.595	0.26
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1201_Y	1204_E	0.595	0.26
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715_V	1150_M	0.594	0.26
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315_M	867_G	0.593	0.26
594_E	743_D	0.593	0.26
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263_M	266_R	0.591	0.26
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113_N	123_V	0.557	0.24
859_S	1170_D	0.557	0.24
265_A	410_L	0.557	0.24
733_Q	767_E	0.557	0.24
971_T	1006_R	0.557	0.24
931_H	934_V	0.556	0.24
743_D	761_L	0.556	0.24
423_E	658_G	0.556	0.24
1318_V	1349_I	0.556	0.24
91_Y	226_V	0.556	0.24
1028_T	1214_N	0.556	0.24
1181_A	1194_L	0.556	0.24
99_S	105_R	0.556	0.24
547_L	969_G	0.555	0.24
1250_N	1371_I	0.555	0.24
31_K	222_A	0.555	0.24
395_Q	589_F	0.555	0.24
74_A	77_R	0.554	0.24
377_T	381_Y	0.554	0.24
525_I	1008_S	0.554	0.24
1244_I	1277_L	0.554	0.24
77_R	87_E	0.554	0.24
17_F	753_A	0.554	0.24
930_S	934_V	0.554	0.24
1107_P	1150_M	0.553	0.24
1107_P	1297_L	0.553	0.24
342_L	489_P	0.553	0.24
222_A	1287_F	0.553	0.24
442_E	550_S	0.552	0.24
82_N	85_L	0.552	0.24
499_L	1277_L	0.552	0.24
322_W	1047_T	0.552	0.24
54_G	248_V	0.552	0.24
91_Y	940_Q	0.551	0.24
316_M	771_R	0.551	0.24
58_D	536_T	0.551	0.24
528_I	1475_K	0.551	0.24
332_K	422_D	0.551	0.24
993_Q	1046_K	0.551	0.24
132_N	557_I	0.550	0.24
142_K	1004_D	0.550	0.24
39_V	174_Q	0.550	0.24
477_K	788_S	0.550	0.24
1171_E	1326_S	0.550	0.24
211_Y	399_L	0.549	0.24
1414_K	1422_I	0.549	0.24
235_F	1022_A	0.549	0.24
324_E	531_Q	0.549	0.24
1461_D	1464_K	0.549	0.24
266_R	543_E	0.549	0.24
1047_T	1321_S	0.548	0.24
352_I	384_F	0.548	0.24
641_H	1358_A	0.548	0.24
1233_A	1275_I	0.548	0.24
184_L	1348_Y	0.548	0.24
647_L	795_G	0.548	0.24
351_A	801_F	0.548	0.24
402_N	675_D	0.548	0.24
511_N	769_Q	0.548	0.24
49_L	1064_H	0.547	0.24
857_A	1159_E	0.547	0.24
1350_N	1448_N	0.547	0.24
1394_F	1413_F	0.547	0.24
1320_S	1390_V	0.547	0.24
262_W	1060_L	0.547	0.24
514_K	668_A	0.547	0.24
1315_K	1442_R	0.547	0.24
711_T	1079_E	0.546	0.24
681_L	737_A	0.546	0.24
124_L	1299_L	0.546	0.24
1443_H	1446_Y	0.546	0.24
106_K	1093_A	0.546	0.24
325_N	1426_S	0.546	0.24
41_Q	391_I	0.545	0.24
623_N	776_Y	0.545	0.24
489_P	740_I	0.545	0.24
286_L	298_N	0.545	0.24
473_E	787_G	0.545	0.24
1220_S	1224_T	0.545	0.24
1405_V	1417_C	0.544	0.23
643_I	915_R	0.544	0.23
101_K	117_E	0.544	0.23
228_S	961_Y	0.544	0.23
488_D	1252_V	0.544	0.23
388_V	414_L	0.544	0.23
489_P	1047_T	0.544	0.23
889_L	1150_M	0.544	0.23
732_A	860_I	0.543	0.23
261_N	733_Q	0.543	0.23
460_D	463_T	0.543	0.23
328_M	334_A	0.543	0.23
11_G	15_P	0.543	0.23
1328_S	1331_N	0.543	0.23
410_L	1085_M	0.543	0.23
1269_G	1275_I	0.543	0.23
54_G	289_D	0.543	0.23
98_F	112_I	0.542	0.23
1389_D	1416_K	0.542	0.23
45_M	48_Q	0.542	0.23
1258_G	1262_S	0.542	0.23
1439_M	1442_R	0.542	0.23
943_M	1037_Y	0.542	0.23
1170_D	1330_D	0.541	0.23
327_H	1416_K	0.541	0.23
221_S	608_I	0.541	0.23
312_H	549_P	0.541	0.23
711_T	714_V	0.541	0.23
822_K	1109_V	0.541	0.23
882_L	1106_A	0.541	0.23
257_R	1015_A	0.541	0.23
871_F	1104_A	0.541	0.23
113_N	744_V	0.540	0.23
1104_A	1116_M	0.540	0.23
653_I	1238_K	0.540	0.23
1216_K	1220_S	0.540	0.23
1100_E	1125_P	0.540	0.23
1046_K	1079_E	0.540	0.23
385_S	765_A	0.539	0.23
1239_E	1274_T	0.539	0.23
511_N	1051_H	0.539	0.23
1455_L	1459_W	0.539	0.23
266_R	1103_F	0.539	0.23
276_G	338_Y	0.539	0.23
1385_V	1455_L	0.539	0.23
1402_I	1436_I	0.539	0.23
1348_Y	1365_N	0.539	0.23
55_Q	1028_T	0.539	0.23
497_A	829_D	0.539	0.23
166_R	884_I	0.538	0.23
561_T	726_V	0.538	0.23
1337_V	1386_V	0.538	0.23
248_V	1083_K	0.538	0.23
376_V	597_L	0.538	0.23
597_L	1075_R	0.538	0.23
447_N	1278_H	0.538	0.23
1184_R	1188_H	0.537	0.23
29_H	1161_M	0.537	0.23
240_R	1054_L	0.537	0.23
564_L	569_F	0.537	0.23
1171_E	1277_L	0.537	0.23
589_F	1346_E	0.537	0.23
596_G	706_Y	0.537	0.23
1272_E	1448_N	0.537	0.23
326_T	1430_E	0.536	0.23
103_D	107_K	0.536	0.23
398_V	1461_D	0.536	0.23
714_V	1007_I	0.536	0.23
1064_H	1128_V	0.536	0.23
1460_E	1463_V	0.536	0.23
82_N	889_L	0.536	0.23
1170_D	1210_Q	0.536	0.23
714_V	1258_G	0.536	0.23
660_A	1079_E	0.535	0.23
115_L	119_E	0.535	0.23
299_A	559_L	0.535	0.23
1101_F	1321_S	0.535	0.23
861_V	891_G	0.534	0.23
110_K	398_V	0.534	0.23
618_S	656_E	0.534	0.23
1383_S	1404_Y	0.534	0.23
295_I	321_P	0.534	0.23
402_N	1085_M	0.534	0.23
1008_S	1090_V	0.534	0.23
340_S	539_W	0.534	0.23
1408_E	1413_F	0.534	0.23
414_L	1120_H	0.534	0.23
842_F	1172_M	0.534	0.23
1110_V	1290_F	0.533	0.23
322_W	775_A	0.533	0.23
826_K	1156_E	0.533	0.23
714_V	718_M	0.533	0.23
1014_K	1058_L	0.533	0.23
652_S	767_E	0.533	0.23
168_L	525_I	0.532	0.23
236_P	947_A	0.531	0.23
683_Y	1150_M	0.531	0.23
211_Y	372_A	0.531	0.23
194_Q	309_K	0.531	0.23
636_S	1003_R	0.531	0.23
136_I	767_E	0.531	0.23
1076_V	1440_L	0.531	0.23
840_F	1250_N	0.530	0.23
60_D	135_K	0.530	0.23
1417_C	1470_I	0.530	0.23
246_Y	289_D	0.530	0.23
380_D	383_I	0.530	0.23
769_Q	773_R	0.530	0.23
76_F	640_Q	0.530	0.23
1116_M	1399_S	0.530	0.23
818_Y	1152_F	0.530	0.23
1231_Q	1260_E	0.530	0.23
240_R	290_G	0.530	0.23
1395_A	1421_M	0.529	0.23
121_Q	153_G	0.529	0.23
633_L	748_Y	0.529	0.23
596_G	686_Y	0.529	0.23
842_F	1179_L	0.529	0.23
542_A	650_K	0.529	0.23
741_S	744_V	0.529	0.23
24_I	385_S	0.528	0.23
873_S	964_V	0.528	0.23
1068_M	1203_P	0.528	0.23
688_Q	1422_I	0.528	0.23
615_L	1349_I	0.527	0.23
1046_K	1083_K	0.527	0.23
460_D	685_T	0.527	0.23
1118_A	1258_G	0.527	0.23
1386_V	1394_F	0.527	0.23
711_T	1150_M	0.527	0.23
641_H	647_L	0.527	0.23
55_Q	351_A	0.527	0.23
1227_L	1260_E	0.526	0.23
390_V	401_K	0.526	0.23
938_E	1108_L	0.526	0.23
20_D	23_G	0.526	0.23
666_F	1334_I	0.526	0.23
54_G	1210_Q	0.526	0.23
586_D	623_N	0.526	0.23
242_H	402_N	0.526	0.23
483_I	1032_I	0.526	0.23
490_L	587_V	0.526	0.23
1054_L	1172_M	0.525	0.22
123_V	131_V	0.525	0.22
816_N	1151_L	0.525	0.22
771_R	1191_A	0.525	0.22
248_V	660_A	0.525	0.22
162_L	194_Q	0.525	0.22
535_S	969_G	0.524	0.22
83_I	86_P	0.524	0.22
126_W	1090_V	0.524	0.22
95_M	189_A	0.524	0.22
262_W	265_A	0.524	0.22
239_E	410_L	0.524	0.22
98_F	148_R	0.524	0.22
353_S	384_F	0.524	0.22
1227_L	1275_I	0.523	0.22
123_V	175_A	0.523	0.22
833_I	1188_H	0.523	0.22
334_A	1060_L	0.523	0.22
1156_E	1431_K	0.523	0.22
903_K	967_V	0.523	0.22
532_L	1392_K	0.523	0.22
821_F	1084_L	0.523	0.22
392_E	1275_I	0.523	0.22
154_A	747_R	0.522	0.22
856_S	861_V	0.522	0.22
719_S	1386_V	0.522	0.22
501_V	1194_L	0.522	0.22
585_I	1410_V	0.522	0.22
404_L	499_L	0.522	0.22
962_P	1481_I	0.522	0.22
177_N	267_E	0.521	0.22
686_Y	699_Y	0.521	0.22
78_K	217_E	0.521	0.22
855_E	1035_S	0.521	0.22
461_L	874_L	0.521	0.22
445_Q	558_K	0.520	0.22
317_L	481_P	0.520	0.22
131_V	141_Q	0.520	0.22
1268_E	1272_E	0.520	0.22
176_E	1266_G	0.520	0.22
1083_K	1259_S	0.520	0.22
1277_L	1295_M	0.520	0.22
248_V	969_G	0.520	0.22
744_V	1093_A	0.520	0.22
39_V	459_S	0.519	0.22
841_A	1290_F	0.519	0.22
1163_A	1166_F	0.519	0.22
1321_S	1326_S	0.519	0.22
895_S	931_H	0.519	0.22
107_K	1263_K	0.519	0.22
569_F	616_I	0.519	0.22
1085_M	1279_F	0.519	0.22
1373_D	1466_F	0.519	0.22
1145_H	1148_N	0.519	0.22
658_G	1338_A	0.519	0.22
49_L	1090_V	0.519	0.22
502_L	1261_I	0.519	0.22
849_L	853_E	0.518	0.22
584_K	1199_L	0.518	0.22
693_G	1246_I	0.518	0.22
667_A	1354_G	0.518	0.22
1007_I	1247_N	0.518	0.22
809_L	1106_A	0.518	0.22
738_V	1128_V	0.518	0.22
536_T	637_A	0.517	0.22
756_L	1198_T	0.517	0.22
584_K	776_Y	0.517	0.22
546_L	585_I	0.517	0.22
391_I	674_A	0.517	0.22
31_K	382_I	0.517	0.22
68_L	204_P	0.517	0.22
595_R	625_R	0.517	0.22
35_T	918_I	0.517	0.22
321_P	536_T	0.516	0.22
623_N	772_H	0.516	0.22
219_F	577_H	0.516	0.22
446_V	676_A	0.516	0.22
710_I	1258_G	0.516	0.22
174_Q	603_Q	0.515	0.22
49_L	203_T	0.515	0.22
55_Q	59_P	0.515	0.22
333_R	1460_E	0.515	0.22
91_Y	1079_E	0.515	0.22
1203_P	1440_L	0.515	0.22
131_V	1200_L	0.515	0.22
597_L	761_L	0.515	0.22
171_I	1203_P	0.514	0.22
1093_A	1164_L	0.514	0.22
1459_W	1463_V	0.514	0.22
244_N	351_A	0.514	0.22
544_G	1099_E	0.514	0.22
46_L	56_G	0.513	0.22
542_A	613_S	0.513	0.22
597_L	737_A	0.513	0.22
225_L	377_T	0.513	0.22
107_K	110_K	0.513	0.22
910_N	931_H	0.513	0.22
770_R	1189_W	0.513	0.22
90_R	136_I	0.513	0.22
312_H	335_F	0.512	0.22
849_L	1171_E	0.512	0.22
99_S	150_V	0.512	0.22
654_I	1480_S	0.512	0.22
285_I	653_I	0.512	0.22
83_I	124_L	0.512	0.22
289_D	1007_I	0.512	0.22
658_G	1092_M	0.512	0.22
487_K	490_L	0.512	0.22
61_T	201_L	0.512	0.22
921_I	1358_A	0.512	0.22
382_I	705_K	0.512	0.22
256_L	295_I	0.511	0.22
1215_H	1226_I	0.511	0.22
563_V	670_I	0.511	0.22
295_I	1085_M	0.511	0.22
597_L	744_V	0.511	0.22
857_A	1143_P	0.511	0.22
1181_A	1196_L	0.511	0.22
35_T	222_A	0.511	0.22
35_T	381_Y	0.511	0.22
119_E	278_D	0.511	0.22
594_E	764_I	0.510	0.22
268_Q	1176_T	0.510	0.22
13_Y	20_D	0.510	0.22
934_V	1262_S	0.510	0.22
963_W	1258_G	0.510	0.22
293_S	736_E	0.510	0.22
1388_G	1398_M	0.510	0.22
464_R	621_K	0.510	0.22
50_D	479_L	0.510	0.22
1080_T	1098_A	0.510	0.22
1085_M	1209_F	0.509	0.22
1025_A	1308_G	0.509	0.22
1230_V	1240_A	0.509	0.22
527_A	1258_G	0.509	0.22
485_E	488_D	0.509	0.22
74_A	658_G	0.509	0.22
462_L	465_Q	0.509	0.22
502_L	509_L	0.508	0.22
152_I	1263_K	0.508	0.22
9_A	1071_G	0.508	0.22
59_P	492_S	0.508	0.22
1090_V	1107_P	0.508	0.22
575_I	744_V	0.508	0.22
423_E	427_T	0.508	0.22
1328_S	1333_I	0.508	0.22
776_Y	1455_L	0.508	0.22
394_E	616_I	0.507	0.21
248_V	1079_E	0.507	0.21
1253_A	1297_L	0.507	0.21
710_I	717_V	0.507	0.21
248_V	1085_M	0.507	0.21
396_E	590_S	0.506	0.21
829_D	1087_G	0.506	0.21
1262_S	1337_V	0.506	0.21
747_R	761_L	0.506	0.21
174_Q	1434_Q	0.506	0.21
1348_Y	1445_A	0.505	0.21
910_N	1266_G	0.505	0.21
172_R	301_E	0.505	0.21
643_I	1063_A	0.505	0.21
1235_E	1265_Y	0.505	0.21
792_W	802_N	0.505	0.21
689_E	826_K	0.505	0.21
115_L	175_A	0.505	0.21
586_D	655_V	0.505	0.21
74_A	118_Q	0.505	0.21
431_T	1445_A	0.505	0.21
535_S	1150_M	0.505	0.21
380_D	457_Q	0.505	0.21
534_T	1079_E	0.505	0.21
201_L	1258_G	0.505	0.21
830_E	1300_D	0.505	0.21
82_N	765_A	0.504	0.21
1025_A	1063_A	0.504	0.21
26_L	354_F	0.504	0.21
247_L	286_L	0.504	0.21
842_F	1173_I	0.504	0.21
402_N	1285_Q	0.504	0.21
810_Q	1116_M	0.504	0.21
557_I	575_I	0.504	0.21
801_F	1122_D	0.504	0.21
895_S	1244_I	0.504	0.21
105_R	150_V	0.504	0.21
630_P	659_E	0.503	0.21
677_I	1445_A	0.503	0.21
54_G	652_S	0.503	0.21
266_R	1107_P	0.503	0.21
595_R	606_K	0.503	0.21
317_L	1340_Y	0.503	0.21
672_Y	745_I	0.503	0.21
1025_A	1178_V	0.503	0.21
1107_P	1146_I	0.502	0.21
1421_M	1472_K	0.502	0.21
911_G	1467_V	0.502	0.21
228_S	1477_M	0.502	0.21
222_A	921_I	0.502	0.21
938_E	1033_V	0.502	0.21
880_E	1103_F	0.502	0.21
162_L	821_F	0.502	0.21
1358_A	1386_V	0.501	0.21
752_T	1075_R	0.501	0.21
285_I	1007_I	0.501	0.21
939_L	1001_A	0.501	0.21
33_K	1204_E	0.501	0.21
813_C	874_L	0.501	0.21
267_E	1028_T	0.501	0.21
835_F	1109_V	0.501	0.21
285_I	608_I	0.501	0.21
1000_N	1216_K	0.501	0.21
715_V	1122_D	0.500	0.21
19_H	195_T	0.500	0.21
58_D	228_S	0.500	0.21
27_Y	38_I	0.500	0.21
205_E	209_A	0.500	0.21
104_E	169_Y	0.500	0.21
338_Y	1404_Y	0.500	0.21
70_Q	223_F	0.500	0.21
589_F	640_Q	0.500	0.21

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
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MTYNQMPKAQGLYRPEFEHDACGIGLYAHLKGKQTHDIVKQGLKMLCQLDHRGGQGSDPDTGDGAGLLVQIPDAFFRKECKNINLPEKERYGVGMVFFSQKEDERKKIEKQINALIEQEGQVVLGWRTVPVNVGKIGTVAQKSCPFVRQVFIGASSDLKDNLSFERKLYVIRKQAENWGVTEGLDFYFASLSSQTIVYKGLLTPEQVDAFYSDLQDEAFVSAFALVHSRFSTNTFPTWERAHPNRYLVHNGEINTLRGNINWMRAREQQFVSESFGEDLNKILPILNADGSDSSILDNAFEFFVMAGRKPAHTAMMLIPEPWTENTHMSKEKRAFYEYHSSLMEPWDGPTAISFTDGKQIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVEQENVLYKNRLEPGKMLLIDLEEGRIISDEEVKTQIATEYPYQKWLEEELVQVNPDPESREEEQFSDLLTRQKAFGYTYEDIQKYLIPVIKEGKDPLGSMGNDAPLAVLSDRAQSLFNYFKQLFAQVTNPPIDAIREQLVTSTMTWLGAEGDLLHPSERNVRRIKLYTPVLSNEQFYALKTIVHPDLKSQKIDVLFSEDLERGLKDMFTQAEKAISQGVSLLILSDKKMNERLTPIPPLLAVSALHQHLIRKGLRTKVSIIVESGEAREVHHFAALIGYGADAINPYLAYATYKQEIDEGRLDISYEEAVSKYGKSITEGVVKVMSKMGISTVQSYRGAQIFEAVGISRDVIDRYFSGTASQLGGIDLQTIAEEAQRRHREAYQDDYSKTLEPGSDFQWRNGGEHHAFNPKTIHTLQWACRRNDYNLFKQYTKAADEERIGFLRNLFAFDGNRKPLKLEEVESAESIVKRFKTGAMSFGSLSKEAHEALAIAMNRLGGKSNSGEGGEDPKRFVPDENGDDRRSAIKQIASGRFGVKSHYLVNADELQIKMAQGAKPGEGGQLPGNKVYPWVADVRGSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANRDARISVKLVSKAGVGTIAAGVAKATADVIVISGYDGGTGASPKTSIKHTGLPWELGLAEAHQTLMLNGLRDRVVLETDGKLMTGRDVVMAALLGAEEFGFATAPLVVLGCVMMRACHLDTCPVGVATQNPELRKKFMGDPDHIVNYMLFIAEEVREYMAALGFKTFDEMIGRTDVLHASERAKEHWKASQLDLSTLLYQPEGVRTFQSPQNHKIDQSLDITTILPAVQEAIESGKEADISIEINNTNRVAGTITGSEISKRYGEEGLPEDTIKLHFTGSAGQSFGAFVPKGMTLYLDGDSNDYVGKGLSGGKIIVKSSEGFNSASDDNVIIGNVAFYGATSGEAYINGRAGERFAVRNSGVNVVVEGIGDHGCEYMTGGSVVVLGDVGKNFAAGMSGGIAYVLTEDVKAFKRKCNLEMILFESLEDEKEIQQIKAMLERHTAYTNSQKAEDLLDQWEDSVKKFVKVIPKNYKQMLASIEEQKAAGLSDEEAIMFAFEANTKPKQNTAASGQKQAVVQ

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Type: Prob:
Scale the weights by the probability

Make symmetric:
List chains interacting with chain A.

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ecfA	4	0.3125	100	0.961	Contact Map
1xffA	2	0.1513	100	0.961	Contact Map
3r2gA	3	0.1947	99.9	0.963	Contact Map
4amvA	2	0.377	99.9	0.964	Contact Map
1te5A	2	0.1461	99.9	0.965	Contact Map
1ao0A	3	0.2572	99.9	0.966	Contact Map
2qr6A	3	0.2171	99.9	0.967	Contact Map
3mdnA	4	0.1382	99.9	0.968	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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