TREC - BACSU - GREMLIN Contacts

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TREC - Trehalose-6-phosphate hydrolase

UniProt:	P39795	Sequences: MKTEQTPWWKKAVVYQIYPKSFNDTTGNGVGDLNGIIEKLDYLKTLQVDVLWLTPIYDSPQHDNGYDIRDYYSIYPEYGTMEDFERLVSEAHKRDLKVVMDLVVNHTSTEHKWFREAISSIDSPYRDFYIWKKPQENGSVPTNWESKFGGSAWELDEASGQYYLHLFDVTQADLNWENEEVRKHVYDMMHFWFEKGIDGFRLDVINLISKDQRFPNAEEGDGRSFYTDGPRVHEFLHEMNEKVFSHYDSMTVGEMSSTTVDHCIRYTNPDNKELDMTFSFHHLKVDYPNGEKWALAPFDFLKLKEILSDWQTGMHAGGGWNALFWCNHDQPRVVSRYGDDGAYRVKSAKMLATAIHMMQGTPYIYQGEELGMTNPKFTDISSYRDVESLNMYHAFKEKGMADQDITAILQAKSRDNSRTPVQWDATENGGFTTGTPWIPVAGNYREINAEAALRDQNSVFYHYQKLIQIRKMYDIVTEGTYEIIAKDDPNIFAYLRHGSNEKLLVINNFYGTEAAFTLPDSLAPDEWKAEVLLTNDEAREGLQNMTLRPYESIVYRLTKPC	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	561 (495)
Sequences:	9540 (6521)
Seq/√Len:	293.1

ECOLI - TREC SUCP MALZ GLGX YGAQ AMY2 GLGB AMY1
BACSU - TREC O16G3 O16G2 O16G1 BBMA GLGB PULA AMY
SULSO - TREZ Q7LX99

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
41_D	94_R	4.925	1.00
85_E	195_K	4.743	1.00
23_N	39_K	4.725	1.00
133_K	161_Q	4.521	1.00
92_H	198_D	4.232	1.00
34_N	86_R	4.185	1.00
90_E	93_K	4.125	1.00
58_D	73_S	3.858	1.00
107_T	129_Y	3.716	1.00
90_E	94_R	3.340	1.00
34_N	37_I	3.228	1.00
43_L	48_V	3.220	1.00
23_N	38_E	3.199	1.00
91_A	98_V	3.036	1.00
58_D	69_R	3.028	1.00
91_A	96_L	3.017	1.00
353_T	462_H	2.973	1.00
37_I	90_E	2.826	1.00
182_R	238_E	2.818	1.00
154_E	169_V	2.672	1.00
353_T	552_S	2.662	1.00
80_T	83_D	2.661	1.00
34_N	83_D	2.518	1.00
233_H	273_E	2.496	1.00
326_C	368_E	2.488	1.00
84_F	88_V	2.473	1.00
461_Y	464_Q	2.451	1.00
45_T	464_Q	2.444	1.00
482_E	495_L	2.339	1.00
40_L	94_R	2.328	1.00
17_I	36_I	2.299	1.00
370_L	449_A	2.295	1.00
495_L	502_K	2.263	1.00
62_H	170_T	2.261	1.00
126_R	159_S	2.259	1.00
72_Y	187_D	2.239	1.00
37_I	86_R	2.237	1.00
110_E	170_T	2.233	1.00
112_K	116_E	2.230	1.00
350_M	507_N	2.179	1.00
86_R	90_E	2.154	1.00
44_K	94_R	2.130	1.00
468_Q	472_M	2.123	1.00
81_M	195_K	2.107	1.00
155_L	160_G	2.091	1.00
548_R	551_E	2.088	1.00
12_A	49_D	2.085	1.00
184_H	187_D	2.032	1.00
36_I	87_L	2.014	1.00
107_T	174_L	2.007	1.00
40_L	91_A	1.970	1.00
357_M	554_V	1.966	1.00
497_H	502_K	1.926	1.00
352_A	463_Y	1.921	1.00
190_H	194_E	1.919	1.00
104_V	185_V	1.906	1.00
493_A	506_I	1.885	1.00
128_F	184_H	1.877	1.00
425_A	450_E	1.874	1.00
27_G	433_T	1.850	1.00
49_D	471_K	1.843	1.00
357_M	494_Y	1.841	1.00
231_R	234_E	1.814	1.00
186_Y	238_E	1.813	1.00
334_V	348_A	1.810	1.00
371_G	459_V	1.807	1.00
189_M	239_M	1.792	1.00
480_T	497_H	1.773	1.00
382_S	439_P	1.771	1.00
384_R	438_I	1.759	1.00
51_L	91_A	1.759	1.00
62_H	168_D	1.758	1.00
13_V	467_I	1.755	1.00
378_T	382_S	1.753	1.00
116_E	119_S	1.744	1.00
118_I	156_D	1.740	1.00
354_A	507_N	1.735	1.00
529_A	532_L	1.733	1.00
482_E	497_H	1.718	1.00
193_F	249_S	1.702	1.00
116_E	123_S	1.693	1.00
190_H	242_K	1.685	1.00
240_N	244_F	1.682	1.00
156_D	159_S	1.679	1.00
345_V	349_K	1.678	1.00
490_N	510_Y	1.666	1.00
529_A	533_L	1.664	1.00
177_E	231_R	1.652	1.00
82_E	85_E	1.634	1.00
45_T	453_L	1.633	1.00
14_V	50_V	1.632	1.00
89_S	93_K	1.629	1.00
453_L	460_F	1.621	1.00
454_R	461_Y	1.615	1.00
109_T	170_T	1.606	1.00
515_A	544_N	1.599	1.00
495_L	504_L	1.598	1.00
529_A	534_T	1.591	1.00
56_I	100_M	1.575	1.00
34_N	38_E	1.560	1.00
116_E	125_Y	1.556	1.00
424_D	450_E	1.553	1.00
56_I	74_I	1.551	1.00
73_S	81_M	1.547	1.00
513_E	546_T	1.546	1.00
183_K	242_K	1.546	1.00
70_D	73_S	1.530	1.00
532_L	535_N	1.524	1.00
72_Y	191_F	1.524	1.00
349_K	462_H	1.513	1.00
84_F	100_M	1.501	1.00
124_P	180_E	1.501	1.00
515_A	546_T	1.500	1.00
11_K	478_E	1.498	1.00
183_K	187_D	1.498	1.00
373_T	443_N	1.495	1.00
58_D	76_P	1.483	1.00
7_P	10_K	1.477	1.00
72_Y	188_M	1.476	1.00
30_V	77_E	1.472	1.00
530_E	533_L	1.465	1.00
428_N	434_G	1.464	1.00
353_T	466_L	1.464	1.00
45_T	460_F	1.447	1.00
112_K	115_R	1.440	1.00
58_D	70_D	1.429	1.00
125_Y	128_F	1.424	1.00
460_F	464_Q	1.420	1.00
72_Y	184_H	1.415	1.00
473_Y	501_E	1.393	1.00
507_N	552_S	1.381	1.00
449_A	460_F	1.381	1.00
453_L	461_Y	1.375	1.00
184_H	188_M	1.374	1.00
37_I	87_L	1.367	1.00
62_H	110_E	1.365	1.00
465_K	468_Q	1.364	1.00
305_E	309_D	1.362	1.00
262_H	265_R	1.360	1.00
61_Q	75_Y	1.360	1.00
428_N	432_T	1.353	1.00
475_I	503_L	1.345	1.00
494_Y	505_V	1.340	1.00
102_L	189_M	1.339	1.00
36_I	53_L	1.339	1.00
325_W	351_L	1.329	1.00
452_A	461_Y	1.326	1.00
237_H	273_E	1.321	1.00
12_A	50_V	1.320	1.00
107_T	181_V	1.316	1.00
56_I	84_F	1.314	1.00
109_T	172_A	1.312	1.00
180_E	183_K	1.302	1.00
464_Q	468_Q	1.302	1.00
57_Y	100_M	1.297	1.00
88_V	98_V	1.296	1.00
11_K	477_T	1.295	1.00
110_E	115_R	1.293	1.00
74_I	84_F	1.292	1.00
490_N	514_A	1.290	1.00
530_E	534_T	1.285	1.00
120_S	123_S	1.280	1.00
357_M	476_V	1.278	1.00
237_H	272_K	1.271	1.00
356_H	467_I	1.254	1.00
455_D	461_Y	1.253	1.00
333_V	337_Y	1.253	1.00
83_D	86_R	1.248	1.00
115_R	118_I	1.245	1.00
84_F	197_I	1.243	1.00
16_Q	54_T	1.236	1.00
350_M	509_F	1.233	1.00
326_C	333_V	1.232	1.00
126_R	156_D	1.229	1.00
99_V	199_G	1.225	1.00
115_R	119_S	1.213	1.00
308_S	481_Y	1.207	1.00
231_R	235_F	1.206	1.00
33_L	74_I	1.206	1.00
421_V	449_A	1.203	1.00
372_M	422_Q	1.201	1.00
104_V	189_M	1.182	1.00
308_S	312_T	1.182	1.00
53_L	56_I	1.181	1.00
320_W	361_T	1.178	1.00
186_Y	242_K	1.165	1.00
478_E	498_G	1.162	1.00
127_D	178_N	1.159	1.00
119_S	123_S	1.158	1.00
517_T	544_N	1.157	1.00
19_P	36_I	1.157	1.00
44_K	96_L	1.154	1.00
117_A	131_W	1.146	1.00
473_Y	503_L	1.144	1.00
157_E	160_G	1.142	1.00
179_E	183_K	1.139	1.00
20_K	77_E	1.137	1.00
176_W	185_V	1.123	1.00
117_A	159_S	1.116	1.00
151_S	154_E	1.115	1.00
476_V	503_L	1.110	1.00
104_V	202_L	1.102	1.00
194_E	246_H	1.101	1.00
99_V	250_M	1.096	1.00
17_I	43_L	1.095	1.00
33_L	56_I	1.094	1.00
61_Q	77_E	1.088	1.00
302_K	305_E	1.087	1.00
475_I	501_E	1.086	1.00
348_A	459_V	1.084	1.00
345_V	455_D	1.083	1.00
43_L	51_L	1.082	1.00
116_E	120_S	1.078	1.00
183_K	186_Y	1.069	1.00
24_D	29_G	1.056	1.00
167_F	207_L	1.050	1.00
418_R	421_V	1.040	1.00
85_E	89_S	1.037	1.00
475_I	498_G	1.035	1.00
121_I	161_Q	1.028	1.00
127_D	130_I	1.023	1.00
58_D	75_Y	1.021	1.00
510_Y	514_A	1.018	1.00
506_I	553_I	1.016	1.00
7_P	248_D	1.015	1.00
134_P	155_L	1.014	1.00
237_H	241_E	1.013	1.00
349_K	459_V	1.010	1.00
37_I	41_D	1.010	1.00
308_S	483_I	1.003	1.00
193_F	243_V	1.002	1.00
357_M	466_L	1.002	1.00
33_L	84_F	1.001	1.00
343_Y	346_K	0.993	1.00
265_R	268_N	0.991	1.00
44_K	95_D	0.988	1.00
100_M	197_I	0.987	1.00
24_D	30_V	0.987	1.00
191_F	195_K	0.987	1.00
497_H	500_N	0.985	1.00
34_N	80_T	0.985	1.00
299_D	302_K	0.985	1.00
120_S	159_S	0.982	1.00
87_L	98_V	0.981	1.00
529_A	535_N	0.980	1.00
301_L	305_E	0.977	1.00
354_A	509_F	0.975	1.00
146_S	150_G	0.975	1.00
132_K	214_F	0.966	1.00
41_D	90_E	0.960	1.00
209_S	231_R	0.954	1.00
364_I	463_Y	0.946	1.00
334_V	337_Y	0.945	1.00
39_K	42_Y	0.944	1.00
48_V	96_L	0.940	1.00
209_S	229_G	0.932	1.00
450_E	454_R	0.930	1.00
252_V	363_Y	0.928	1.00
25_T	34_N	0.926	1.00
123_S	126_R	0.926	1.00
488_D	514_A	0.925	1.00
177_E	235_F	0.918	1.00
19_P	54_T	0.917	1.00
127_D	175_N	0.916	1.00
182_R	235_F	0.914	1.00
86_R	89_S	0.914	1.00
205_I	208_I	0.914	1.00
146_S	149_G	0.908	1.00
182_R	186_Y	0.907	1.00
461_Y	465_K	0.907	1.00
205_I	236_L	0.907	1.00
81_M	191_F	0.907	1.00
240_N	245_S	0.907	1.00
50_V	97_K	0.903	1.00
204_V	207_L	0.903	1.00
188_M	191_F	0.902	1.00
339_D	511_G	0.901	1.00
185_V	188_M	0.898	1.00
260_V	313_G	0.897	1.00
299_D	489_P	0.894	1.00
50_V	250_M	0.893	1.00
119_S	158_A	0.893	1.00
97_K	198_D	0.892	1.00
128_F	180_E	0.892	1.00
250_M	276_M	0.892	1.00
506_I	545_M	0.891	1.00
483_I	486_K	0.885	1.00
474_D	478_E	0.884	1.00
26_T	30_V	0.883	1.00
40_L	90_E	0.882	1.00
265_R	269_P	0.881	1.00
228_D	262_H	0.881	1.00
301_L	489_P	0.880	1.00
382_S	435_T	0.879	1.00
529_A	553_I	0.878	1.00
14_V	363_Y	0.877	1.00
530_E	535_N	0.877	1.00
211_D	225_F	0.876	1.00
244_F	275_D	0.875	1.00
126_R	161_Q	0.875	1.00
152_A	164_L	0.874	1.00
13_V	48_V	0.867	1.00
357_M	505_V	0.866	1.00
82_E	86_R	0.866	1.00
260_V	264_I	0.866	1.00
209_S	235_F	0.866	1.00
474_D	477_T	0.865	1.00
338_G	347_S	0.864	1.00
81_M	85_E	0.862	1.00
429_G	440_V	0.858	1.00
60_P	69_R	0.853	1.00
519_P	522_L	0.853	1.00
484_I	504_L	0.850	1.00
484_I	495_L	0.849	1.00
474_D	501_E	0.849	1.00
490_N	512_T	0.847	1.00
241_E	245_S	0.845	1.00
116_E	124_P	0.842	1.00
19_P	53_L	0.841	1.00
88_V	197_I	0.840	1.00
469_I	473_Y	0.839	1.00
51_L	87_L	0.835	1.00
155_L	159_S	0.834	1.00
43_L	96_L	0.831	1.00
493_A	504_L	0.830	1.00
481_Y	492_F	0.830	1.00
32_D	35_G	0.830	1.00
33_L	83_D	0.829	1.00
356_H	362_P	0.828	1.00
125_Y	180_E	0.826	1.00
14_V	99_V	0.824	1.00
432_T	436_P	0.821	1.00
203_D	329_D	0.820	1.00
42_Y	460_F	0.819	1.00
511_G	550_Y	0.817	1.00
264_I	268_N	0.817	1.00
304_K	308_S	0.817	1.00
242_K	245_S	0.816	1.00
121_I	133_K	0.816	1.00
24_D	28_N	0.812	1.00
547_L	551_E	0.812	1.00
189_M	243_V	0.810	1.00
449_A	453_L	0.807	1.00
84_F	87_L	0.807	1.00
27_G	434_G	0.804	1.00
121_I	159_S	0.803	1.00
448_N	451_A	0.803	1.00
202_L	274_L	0.802	0.99
531_V	534_T	0.799	0.99
376_K	383_Y	0.798	0.99
281_H	284_K	0.797	0.99
325_W	354_A	0.796	0.99
62_H	109_T	0.795	0.99
283_L	286_D	0.794	0.99
344_R	347_S	0.793	0.99
91_A	94_R	0.793	0.99
33_L	87_L	0.792	0.99
211_D	214_F	0.792	0.99
422_Q	440_V	0.791	0.99
37_I	83_D	0.790	0.99
513_E	548_R	0.789	0.99
306_I	309_D	0.789	0.99
243_V	251_T	0.787	0.99
346_K	349_K	0.787	0.99
307_L	358_M	0.786	0.99
352_A	459_V	0.786	0.99
75_Y	78_Y	0.785	0.99
155_L	158_A	0.784	0.99
190_H	246_H	0.784	0.99
25_T	28_N	0.783	0.99
8_W	12_A	0.782	0.99
264_I	267_T	0.781	0.99
379_D	382_S	0.780	0.99
20_K	61_Q	0.779	0.99
89_S	92_H	0.779	0.99
201_R	329_D	0.778	0.99
53_L	87_L	0.777	0.99
462_H	552_S	0.775	0.99
61_Q	78_Y	0.774	0.99
19_P	33_L	0.772	0.99
16_Q	19_P	0.768	0.99
278_F	363_Y	0.768	0.99
303_L	307_L	0.762	0.99
353_T	554_V	0.760	0.99
453_L	464_Q	0.759	0.99
234_E	237_H	0.756	0.99
425_A	451_A	0.756	0.99
498_G	501_E	0.756	0.99
288_P	294_A	0.755	0.99
355_I	362_P	0.755	0.99
373_T	447_I	0.755	0.99
194_E	247_Y	0.755	0.99
422_Q	429_G	0.753	0.99
419_T	422_Q	0.753	0.99
190_H	245_S	0.751	0.99
131_W	134_P	0.749	0.99
533_L	536_D	0.748	0.99
238_E	241_E	0.746	0.99
145_E	149_G	0.746	0.99
268_N	272_K	0.746	0.99
25_T	36_I	0.745	0.99
375_P	378_T	0.745	0.99
255_M	259_T	0.744	0.99
50_V	99_V	0.744	0.99
284_K	287_Y	0.742	0.99
425_A	428_N	0.742	0.99
281_H	309_D	0.740	0.99
37_I	94_R	0.737	0.99
12_A	97_K	0.737	0.99
102_L	202_L	0.736	0.99
186_Y	239_M	0.735	0.99
119_S	125_Y	0.734	0.99
332_R	335_S	0.734	0.99
288_P	297_P	0.731	0.99
211_D	229_G	0.730	0.99
92_H	97_K	0.730	0.99
325_W	355_I	0.727	0.99
370_L	422_Q	0.726	0.99
476_V	479_G	0.724	0.99
491_I	516_F	0.718	0.99
335_S	338_G	0.717	0.99
446_E	451_A	0.716	0.99
418_R	422_Q	0.716	0.99
104_V	188_M	0.716	0.99
211_D	231_R	0.713	0.99
146_S	152_A	0.712	0.99
370_L	452_A	0.709	0.99
177_E	209_S	0.709	0.99
443_N	447_I	0.708	0.99
168_D	171_Q	0.706	0.99
276_M	361_T	0.704	0.99
13_V	356_H	0.704	0.99
183_K	238_E	0.703	0.99
424_D	428_N	0.703	0.99
375_P	383_Y	0.700	0.99
117_A	123_S	0.699	0.99
113_W	174_L	0.699	0.99
189_M	202_L	0.698	0.99
506_I	547_L	0.697	0.99
427_E	431_F	0.695	0.99
146_S	151_S	0.694	0.99
41_D	45_T	0.691	0.99
491_I	547_L	0.691	0.99
256_S	330_Q	0.691	0.99
266_Y	270_D	0.691	0.99
130_I	133_K	0.690	0.98
48_V	51_L	0.690	0.98
103_V	106_H	0.689	0.98
207_L	227_T	0.688	0.98
42_Y	449_A	0.688	0.98
105_N	173_D	0.688	0.98
167_F	171_Q	0.688	0.98
151_S	155_L	0.686	0.98
420_P	423_W	0.685	0.98
521_S	524_P	0.683	0.98
206_N	255_M	0.682	0.98
166_L	226_Y	0.681	0.98
117_A	126_R	0.681	0.98
383_Y	386_V	0.679	0.98
306_I	310_W	0.677	0.98
68_I	103_V	0.677	0.98
238_E	242_K	0.676	0.98
53_L	84_F	0.672	0.98
7_P	478_E	0.671	0.98
301_L	304_K	0.671	0.98
236_L	239_M	0.670	0.98
451_A	454_R	0.670	0.98
337_Y	351_L	0.669	0.98
174_L	181_V	0.665	0.98
452_A	455_D	0.665	0.98
150_G	154_E	0.664	0.98
240_N	275_D	0.663	0.98
149_G	152_A	0.663	0.98
123_S	159_S	0.662	0.98
142_T	213_R	0.658	0.98
307_L	310_W	0.657	0.98
122_D	125_Y	0.657	0.98
31_G	35_G	0.656	0.98
126_R	129_Y	0.656	0.98
511_G	549_P	0.656	0.98
456_Q	461_Y	0.655	0.98
24_D	32_D	0.655	0.98
457_N	461_Y	0.654	0.98
262_H	268_N	0.654	0.98
495_L	498_G	0.654	0.98
119_S	156_D	0.653	0.98
325_W	333_V	0.653	0.98
383_Y	413_S	0.652	0.98
42_Y	453_L	0.651	0.98
124_P	128_F	0.651	0.98
283_L	287_Y	0.649	0.98
309_D	313_G	0.649	0.98
347_S	550_Y	0.649	0.98
142_T	152_A	0.648	0.98
228_D	266_Y	0.647	0.98
280_F	283_L	0.645	0.98
444_Y	448_N	0.645	0.98
126_R	130_I	0.645	0.98
260_V	263_C	0.644	0.98
135_Q	138_G	0.643	0.98
428_N	435_T	0.643	0.98
236_L	240_N	0.643	0.98
345_V	457_N	0.642	0.98
203_D	328_H	0.642	0.98
111_H	114_F	0.641	0.98
150_G	153_W	0.640	0.98
206_N	258_T	0.639	0.98
432_T	435_T	0.637	0.97
40_L	96_L	0.635	0.97
441_A	444_Y	0.635	0.97
353_T	507_N	0.635	0.97
333_V	351_L	0.635	0.97
60_P	63_D	0.634	0.97
425_A	448_N	0.633	0.97
98_V	198_D	0.632	0.97
260_V	268_N	0.632	0.97
121_I	126_R	0.630	0.97
424_D	448_N	0.630	0.97
253_G	274_L	0.624	0.97
208_I	232_V	0.624	0.97
183_K	190_H	0.624	0.97
42_Y	45_T	0.623	0.97
175_N	178_N	0.623	0.97
267_T	319_G	0.622	0.97
260_V	265_R	0.621	0.97
262_H	270_D	0.620	0.97
235_F	239_M	0.620	0.97
118_I	121_I	0.620	0.97
240_N	251_T	0.619	0.97
66_Y	203_D	0.618	0.97
481_Y	494_Y	0.618	0.97
166_L	207_L	0.618	0.97
206_N	256_S	0.617	0.97
142_T	146_S	0.616	0.97
312_T	482_E	0.615	0.97
126_R	131_W	0.613	0.97
422_Q	426_T	0.613	0.97
300_F	304_K	0.612	0.97
259_T	262_H	0.611	0.97
233_H	237_H	0.610	0.97
7_P	11_K	0.610	0.97
302_K	306_I	0.609	0.97
102_L	200_F	0.608	0.97
114_F	129_Y	0.608	0.97
66_Y	201_R	0.608	0.97
263_C	269_P	0.607	0.97
296_A	302_K	0.605	0.97
66_Y	329_D	0.604	0.97
246_H	249_S	0.604	0.97
118_I	158_A	0.604	0.97
296_A	299_D	0.602	0.96
425_A	429_G	0.601	0.96
368_E	463_Y	0.601	0.96
18_Y	54_T	0.599	0.96
428_N	431_F	0.599	0.96
356_H	466_L	0.598	0.96
356_H	364_I	0.598	0.96
193_F	246_H	0.598	0.96
147_K	227_T	0.597	0.96
59_S	63_D	0.597	0.96
134_P	138_G	0.597	0.96
344_R	452_A	0.595	0.96
339_D	342_A	0.594	0.96
485_A	488_D	0.592	0.96
148_F	153_W	0.589	0.96
58_D	78_Y	0.588	0.96
425_A	445_R	0.587	0.96
282_H	303_L	0.587	0.96
353_T	357_M	0.586	0.96
87_L	91_A	0.586	0.96
190_H	243_V	0.585	0.96
119_S	122_D	0.584	0.96
49_D	96_L	0.584	0.96
345_V	459_V	0.582	0.96
117_A	156_D	0.582	0.96
181_V	184_H	0.582	0.96
480_T	495_L	0.581	0.96
204_V	208_I	0.581	0.96
61_Q	64_N	0.579	0.96
201_R	328_H	0.578	0.96
413_S	416_N	0.577	0.96
26_T	32_D	0.577	0.96
311_Q	359_Q	0.577	0.96
255_M	277_T	0.576	0.95
531_V	535_N	0.576	0.95
102_L	188_M	0.576	0.95
426_T	430_G	0.575	0.95
187_D	190_H	0.575	0.95
418_R	423_W	0.574	0.95
414_R	418_R	0.574	0.95
265_R	270_D	0.573	0.95
17_I	22_F	0.572	0.95
50_V	96_L	0.572	0.95
23_N	35_G	0.571	0.95
262_H	266_Y	0.571	0.95
156_D	160_G	0.570	0.95
483_I	492_F	0.570	0.95
274_L	277_T	0.568	0.95
270_D	273_E	0.567	0.95
266_Y	269_P	0.567	0.95
25_T	87_L	0.566	0.95
452_A	458_S	0.566	0.95
307_L	311_Q	0.565	0.95
103_V	203_D	0.565	0.95
118_I	159_S	0.564	0.95
203_D	254_E	0.564	0.95
430_G	433_T	0.563	0.95
356_H	368_E	0.563	0.95
228_D	257_S	0.563	0.95
256_S	284_K	0.563	0.95
147_K	207_L	0.562	0.95
263_C	268_N	0.562	0.95
145_E	148_F	0.561	0.95
53_L	91_A	0.560	0.95
69_R	110_E	0.560	0.95
182_R	209_S	0.560	0.95
262_H	269_P	0.559	0.95
349_K	458_S	0.559	0.95
104_V	239_M	0.558	0.95
88_V	198_D	0.558	0.95
193_F	247_Y	0.557	0.95
142_T	214_F	0.557	0.95
106_H	203_D	0.556	0.95
142_T	212_Q	0.555	0.94
189_M	200_F	0.554	0.94
101_D	201_R	0.554	0.94
262_H	267_T	0.553	0.94
106_H	328_H	0.553	0.94
88_V	100_M	0.553	0.94
264_I	269_P	0.553	0.94
517_T	520_D	0.552	0.94
503_L	530_E	0.552	0.94
180_E	184_H	0.552	0.94
469_I	554_V	0.552	0.94
536_D	548_R	0.552	0.94
159_S	162_Y	0.552	0.94
116_E	122_D	0.551	0.94
278_F	283_L	0.550	0.94
505_V	554_V	0.550	0.94
113_W	184_H	0.549	0.94
415_D	418_R	0.549	0.94
187_D	194_E	0.548	0.94
342_A	346_K	0.547	0.94
147_K	151_S	0.546	0.94
229_G	232_V	0.546	0.94
14_V	361_T	0.546	0.94
42_Y	48_V	0.545	0.94
491_I	514_A	0.545	0.94
335_S	374_N	0.545	0.94
19_P	78_Y	0.544	0.94
239_M	243_V	0.544	0.94
540_E	543_Q	0.543	0.94
202_L	244_F	0.543	0.94
474_D	498_G	0.543	0.94
186_Y	190_H	0.542	0.94
125_Y	129_Y	0.542	0.94
286_D	412_K	0.542	0.94
37_I	91_A	0.541	0.94
134_P	137_N	0.541	0.94
483_I	487_D	0.540	0.94
260_V	267_T	0.540	0.94
134_P	162_Y	0.539	0.94
429_G	444_Y	0.539	0.94
424_D	427_E	0.538	0.94
529_A	555_Y	0.537	0.93
352_A	364_I	0.536	0.93
520_D	523_A	0.536	0.93
427_E	432_T	0.536	0.93
255_M	258_T	0.535	0.93
114_F	117_A	0.534	0.93
353_T	505_V	0.534	0.93
22_F	36_I	0.534	0.93
120_S	126_R	0.534	0.93
536_D	540_E	0.533	0.93
88_V	92_H	0.532	0.93
331_P	374_N	0.531	0.93
167_F	172_A	0.530	0.93
352_A	466_L	0.530	0.93
350_M	550_Y	0.530	0.93
443_N	446_E	0.529	0.93
542_L	545_M	0.529	0.93
484_I	493_A	0.529	0.93
168_D	386_V	0.528	0.93
256_S	259_T	0.527	0.93
264_I	318_G	0.526	0.93
467_I	471_K	0.526	0.93
324_F	327_N	0.526	0.93
346_K	548_R	0.526	0.93
506_I	555_Y	0.525	0.93
415_D	419_T	0.525	0.93
383_Y	412_K	0.524	0.93
536_D	539_R	0.524	0.93
148_F	151_S	0.523	0.93
177_E	212_Q	0.523	0.93
323_L	360_G	0.522	0.93
439_P	442_G	0.522	0.93
20_K	78_Y	0.521	0.92
492_F	507_N	0.520	0.92
124_P	184_H	0.519	0.92
366_Q	421_V	0.519	0.92
416_N	419_T	0.518	0.92
473_Y	476_V	0.517	0.92
412_K	416_N	0.516	0.92
112_K	125_Y	0.514	0.92
308_S	311_Q	0.514	0.92
435_T	439_P	0.514	0.92
348_A	352_A	0.514	0.92
143_N	146_S	0.514	0.92
275_D	280_F	0.514	0.92
66_Y	328_H	0.513	0.92
435_T	438_I	0.512	0.92
305_E	308_S	0.511	0.92
422_Q	425_A	0.511	0.92
276_M	280_F	0.511	0.92
339_D	343_Y	0.510	0.92
144_W	148_F	0.510	0.92
331_P	334_V	0.510	0.92
452_A	460_F	0.509	0.92
419_T	429_G	0.509	0.92
260_V	270_D	0.507	0.91
176_W	208_I	0.507	0.91
106_H	201_R	0.507	0.91
128_F	131_W	0.506	0.91
530_E	536_D	0.505	0.91
451_A	455_D	0.505	0.91
536_D	541_G	0.505	0.91
333_V	463_Y	0.504	0.91
429_G	432_T	0.504	0.91
25_T	29_G	0.504	0.91
82_E	195_K	0.504	0.91
130_I	177_E	0.503	0.91
240_N	272_K	0.503	0.91
354_A	357_M	0.503	0.91
332_R	336_R	0.503	0.91
315_H	480_T	0.502	0.91
475_I	497_H	0.502	0.91
331_P	335_S	0.501	0.91
202_L	205_I	0.501	0.91
459_V	462_H	0.500	0.91
20_K	75_Y	0.500	0.91
484_I	487_D	0.500	0.91
518_L	521_S	0.500	0.91

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2ze0A	2	0.9394	100	0.165	Contact Map
1uokA	1	0.984	100	0.172	Contact Map
4mb1A	1	0.9733	100	0.176	Contact Map
4hphA	1	0.9857	100	0.184	Contact Map
1zjaA	1	0.9822	100	0.186	Contact Map
3aj7A	1	0.9857	100	0.189	Contact Map
4aieA	1	0.9554	100	0.19	Contact Map
2zicA	1	0.9501	100	0.197	Contact Map
3wy2A	1	0.9198	100	0.199	Contact Map
3zo9A	4	0.9091	100	0.227	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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