SYN - BACSU - GREMLIN Contacts

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SYN - Asparagine--tRNA ligase

UniProt:	P39772	Sequences: MKTTINQVYKHVGEEVTIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEESIFQTAKSVTQETSLYIKGIVKEDERSPLGYELAVTDIEVIHEATDYPITPKEHGTEFLMDHRHLWLRSKRQHAIMKIRNEIIRATYEFFNNEGFVKVDPPILTGSAPEGTTELFATKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLQVQENYVSFIVQSVLKNCKIELNTLGRDTSKLEQIKAPFPRITYDEAIEFLKEKGFDDIEWGDDFGAPHETAIAEHYDKPVFITRYPTSLKPFYMQPASDREDVVLCADLIAPEGYGEIIGGSERIHDMELLESRLKEHGLDSDAYKWYAELRKYGSVPHSGFGLGLERTVAWISGAPHVRETIPFPRLLNRLYP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	430 (406)
Sequences:	9351 (4739)
Seq/√Len:	235.2

ECOLI - SYN SYK1 SYK2 SYD EPMA
BACSU - SYN SYK SYDND
HALSA - SYDND
SULSO - SYDND SYK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
147_E	240_N	4.531	1.00
72_K	91_D	3.898	1.00
45_G	89_V	3.795	1.00
11_H	14_E	3.709	1.00
145_N	199_F	3.650	1.00
17_T	72_K	3.534	1.00
15_E	72_K	3.513	1.00
138_R	142_E	3.483	1.00
143_F	240_N	3.415	1.00
15_E	90_T	3.264	1.00
138_R	145_N	3.213	1.00
142_E	146_N	3.189	1.00
70_Y	93_E	2.912	1.00
139_A	248_S	2.860	1.00
188_M	198_V	2.804	1.00
139_A	244_F	2.758	1.00
229_V	233_E	2.723	1.00
359_E	396_S	2.678	1.00
269_Q	282_A	2.658	1.00
132_I	410_S	2.423	1.00
156_I	205_F	2.418	1.00
45_G	71_I	2.347	1.00
192_A	395_H	2.285	1.00
140_T	222_I	2.275	1.00
19_G	70_Y	2.232	1.00
136_I	406_V	2.207	1.00
99_T	389_K	2.191	1.00
137_I	402_L	2.125	1.00
141_Y	151_K	2.095	1.00
43_I	87_L	2.079	1.00
247_Q	253_C	2.076	1.00
156_I	202_G	2.067	1.00
170_A	177_D	2.058	1.00
142_E	145_N	2.034	1.00
368_E	372_K	2.011	1.00
15_E	74_I	1.995	1.00
74_I	90_T	1.994	1.00
372_K	378_S	1.986	1.00
134_N	145_N	1.986	1.00
347_A	354_I	1.985	1.00
244_F	248_S	1.967	1.00
226_M	229_V	1.949	1.00
129_I	412_A	1.930	1.00
320_R	332_P	1.920	1.00
16_V	87_L	1.908	1.00
142_E	248_S	1.880	1.00
13_G	74_I	1.876	1.00
143_F	244_F	1.876	1.00
231_F	341_L	1.875	1.00
143_F	147_E	1.861	1.00
140_T	241_Y	1.858	1.00
224_P	398_F	1.832	1.00
18_I	43_I	1.825	1.00
143_F	241_Y	1.807	1.00
236_Q	240_N	1.806	1.00
234_N	396_S	1.784	1.00
277_I	314_K	1.781	1.00
76_K	88_A	1.768	1.00
127_H	131_K	1.760	1.00
236_Q	276_R	1.751	1.00
146_N	244_F	1.748	1.00
317_F	345_L	1.741	1.00
364_M	368_E	1.736	1.00
139_A	245_I	1.722	1.00
369_S	373_E	1.719	1.00
242_V	345_L	1.706	1.00
152_V	191_A	1.679	1.00
230_E	233_E	1.654	1.00
131_K	150_V	1.648	1.00
333_A	341_L	1.622	1.00
239_E	276_R	1.586	1.00
278_T	320_R	1.584	1.00
332_P	341_L	1.572	1.00
368_E	385_A	1.564	1.00
172_K	175_D	1.562	1.00
149_F	226_M	1.558	1.00
284_E	288_E	1.542	1.00
368_E	378_S	1.534	1.00
17_T	70_Y	1.526	1.00
297_G	300_F	1.525	1.00
364_M	389_K	1.524	1.00
128_A	132_I	1.524	1.00
309_A	312_Y	1.521	1.00
301_G	305_E	1.520	1.00
369_S	372_K	1.514	1.00
22_V	69_L	1.505	1.00
296_W	300_F	1.501	1.00
74_I	88_A	1.480	1.00
275_P	285_F	1.474	1.00
226_M	237_V	1.470	1.00
243_S	272_A	1.464	1.00
148_G	197_K	1.463	1.00
22_V	34_L	1.454	1.00
281_E	284_E	1.453	1.00
135_E	138_R	1.450	1.00
295_E	298_D	1.450	1.00
113_L	120_W	1.446	1.00
124_K	128_A	1.421	1.00
22_V	63_V	1.412	1.00
335_D	338_D	1.409	1.00
331_Q	362_H	1.409	1.00
246_V	409_I	1.406	1.00
211_K	214_R	1.400	1.00
172_K	177_D	1.400	1.00
278_T	281_E	1.395	1.00
331_Q	363_D	1.394	1.00
277_I	282_A	1.393	1.00
377_D	380_A	1.389	1.00
12_V	77_E	1.386	1.00
125_R	412_A	1.374	1.00
281_E	285_F	1.369	1.00
204_T	221_M	1.366	1.00
130_M	195_L	1.366	1.00
32_A	57_F	1.359	1.00
229_V	396_S	1.352	1.00
232_E	236_Q	1.349	1.00
359_E	362_H	1.347	1.00
139_A	142_E	1.345	1.00
135_E	248_S	1.344	1.00
136_I	245_I	1.341	1.00
302_A	306_T	1.321	1.00
89_V	92_I	1.318	1.00
40_T	43_I	1.315	1.00
368_E	382_K	1.314	1.00
63_V	69_L	1.309	1.00
139_A	249_V	1.304	1.00
386_E	389_K	1.295	1.00
54_E	58_Q	1.292	1.00
247_Q	251_K	1.291	1.00
30_K	49_K	1.280	1.00
345_L	355_I	1.279	1.00
261_G	265_S	1.278	1.00
300_F	304_H	1.276	1.00
144_F	222_I	1.274	1.00
116_H	386_E	1.256	1.00
222_I	402_L	1.256	1.00
273_P	276_R	1.250	1.00
130_M	420_P	1.248	1.00
70_Y	95_I	1.240	1.00
142_E	244_F	1.233	1.00
197_K	226_M	1.232	1.00
144_F	224_P	1.230	1.00
363_D	366_L	1.225	1.00
366_L	369_S	1.218	1.00
373_E	376_L	1.212	1.00
18_I	36_L	1.200	1.00
31_I	46_V	1.194	1.00
131_K	135_E	1.190	1.00
300_F	303_P	1.186	1.00
135_E	253_C	1.180	1.00
275_P	314_K	1.178	1.00
75_V	85_Y	1.178	1.00
323_T	370_R	1.177	1.00
332_P	339_V	1.176	1.00
184_G	204_T	1.172	1.00
71_I	89_V	1.171	1.00
128_A	131_K	1.168	1.00
75_V	87_L	1.157	1.00
63_V	92_I	1.142	1.00
58_Q	61_K	1.139	1.00
270_I	273_P	1.137	1.00
152_V	195_L	1.131	1.00
24_N	35_Q	1.129	1.00
140_T	402_L	1.128	1.00
35_Q	42_F	1.120	1.00
370_R	373_E	1.107	1.00
186_L	383_W	1.106	1.00
303_P	307_A	1.106	1.00
184_G	221_M	1.093	1.00
193_M	392_S	1.092	1.00
277_I	316_V	1.091	1.00
331_Q	366_L	1.088	1.00
140_T	245_I	1.088	1.00
151_K	199_F	1.088	1.00
315_P	347_A	1.084	1.00
127_H	195_L	1.083	1.00
242_V	405_T	1.082	1.00
37_R	66_E	1.081	1.00
144_F	241_Y	1.079	1.00
132_I	249_V	1.073	1.00
23_A	37_R	1.070	1.00
238_Q	400_L	1.070	1.00
47_V	89_V	1.065	1.00
34_L	45_G	1.062	1.00
153_D	203_P	1.060	1.00
136_I	409_I	1.060	1.00
243_S	255_I	1.059	1.00
18_I	87_L	1.058	1.00
38_D	41_G	1.054	1.00
37_R	42_F	1.052	1.00
209_K	425_L	1.050	1.00
64_T	67_T	1.048	1.00
329_Y	358_S	1.043	1.00
297_G	303_P	1.043	1.00
245_I	249_V	1.042	1.00
136_I	402_L	1.037	1.00
170_A	179_Y	1.031	1.00
239_E	243_S	1.030	1.00
240_N	243_S	1.029	1.00
135_E	145_N	1.027	1.00
147_E	237_V	1.023	1.00
370_R	374_H	1.023	1.00
256_E	259_T	1.013	1.00
62_S	97_E	1.009	1.00
40_T	196_G	1.008	1.00
141_Y	199_F	1.008	1.00
36_L	69_L	1.004	1.00
243_S	253_C	1.002	1.00
287_K	295_E	0.999	1.00
48_V	88_A	0.989	1.00
298_D	301_G	0.987	1.00
412_A	418_T	0.985	1.00
132_I	136_I	0.982	1.00
296_W	299_D	0.977	1.00
63_V	94_V	0.973	1.00
105_P	108_H	0.970	1.00
412_A	417_E	0.970	1.00
258_N	314_K	0.968	1.00
158_T	187_Y	0.967	1.00
270_I	282_A	0.964	1.00
109_G	112_F	0.963	1.00
301_G	304_H	0.962	1.00
320_R	339_V	0.954	1.00
297_G	305_E	0.953	1.00
229_V	234_N	0.950	1.00
282_A	318_I	0.948	1.00
243_S	271_K	0.947	1.00
286_L	311_H	0.944	1.00
137_I	151_K	0.936	1.00
184_G	187_Y	0.935	1.00
78_D	82_P	0.927	1.00
248_S	252_N	0.923	1.00
240_N	244_F	0.923	1.00
16_V	75_V	0.922	1.00
297_G	304_H	0.921	1.00
18_I	71_I	0.917	1.00
299_D	303_P	0.914	1.00
392_S	395_H	0.912	1.00
157_L	178_A	0.911	1.00
233_E	236_Q	0.907	1.00
68_S	96_H	0.905	1.00
191_A	420_P	0.904	1.00
224_P	238_Q	0.904	1.00
323_T	331_Q	0.904	1.00
96_H	392_S	0.903	1.00
241_Y	245_I	0.903	1.00
132_I	135_E	0.903	1.00
184_G	202_G	0.897	0.99
263_D	268_E	0.896	0.99
121_L	130_M	0.893	0.99
43_I	75_V	0.890	0.99
283_I	300_F	0.889	0.99
73_G	87_L	0.887	0.99
143_F	237_V	0.886	0.99
284_E	287_K	0.886	0.99
231_F	235_L	0.883	0.99
234_N	398_F	0.881	0.99
34_L	69_L	0.880	0.99
232_E	276_R	0.876	0.99
294_I	297_G	0.873	0.99
238_Q	398_F	0.868	0.99
277_I	318_I	0.867	0.99
278_T	319_T	0.863	0.99
190_A	421_F	0.861	0.99
57_F	61_K	0.860	0.99
382_K	386_E	0.859	0.99
294_I	302_A	0.858	0.99
364_M	385_A	0.853	0.99
56_I	59_T	0.850	0.99
235_L	276_R	0.848	0.99
258_N	262_R	0.848	0.99
289_K	311_H	0.847	0.99
67_T	97_E	0.847	0.99
294_I	298_D	0.847	0.99
368_E	389_K	0.847	0.99
259_T	262_R	0.843	0.99
118_H	386_E	0.842	0.99
71_I	87_L	0.842	0.99
332_P	335_D	0.839	0.99
125_R	129_I	0.838	0.99
134_N	138_R	0.834	0.99
301_G	325_L	0.832	0.99
214_R	352_G	0.829	0.99
132_I	250_L	0.824	0.99
376_L	381_Y	0.822	0.99
299_D	305_E	0.821	0.99
27_S	30_K	0.820	0.99
371_L	381_Y	0.817	0.99
232_E	259_T	0.815	0.99
27_S	32_A	0.814	0.99
149_F	197_K	0.813	0.99
192_A	227_A	0.813	0.99
361_I	366_L	0.813	0.99
47_V	60_A	0.811	0.99
137_I	222_I	0.809	0.99
39_G	131_K	0.808	0.99
256_E	411_G	0.803	0.99
238_Q	355_I	0.802	0.99
282_A	308_I	0.802	0.99
147_E	197_K	0.801	0.99
268_E	285_F	0.799	0.99
268_E	271_K	0.794	0.99
64_T	97_E	0.792	0.99
28_S	31_I	0.789	0.99
139_A	143_F	0.788	0.99
332_P	366_L	0.786	0.99
34_L	47_V	0.786	0.99
354_I	405_T	0.785	0.99
280_D	296_W	0.783	0.99
21_W	228_F	0.780	0.99
245_I	248_S	0.780	0.99
129_I	410_S	0.779	0.99
59_T	62_S	0.774	0.99
303_P	306_T	0.769	0.98
277_I	285_F	0.769	0.98
55_S	58_Q	0.768	0.98
23_A	42_F	0.768	0.98
193_M	388_R	0.768	0.98
254_K	258_N	0.766	0.98
271_K	276_R	0.766	0.98
224_P	234_N	0.762	0.98
294_I	300_F	0.761	0.98
104_T	107_E	0.761	0.98
304_H	307_A	0.761	0.98
265_S	269_Q	0.757	0.98
68_S	393_V	0.754	0.98
57_F	60_A	0.754	0.98
295_E	324_S	0.753	0.98
248_S	251_K	0.752	0.98
282_A	286_L	0.752	0.98
224_P	237_V	0.752	0.98
24_N	65_Q	0.751	0.98
192_A	392_S	0.750	0.98
263_D	339_V	0.750	0.98
37_R	124_K	0.749	0.98
259_T	411_G	0.748	0.98
229_V	237_V	0.748	0.98
258_N	411_G	0.747	0.98
239_E	273_P	0.745	0.98
134_N	199_F	0.744	0.98
297_G	301_G	0.743	0.98
296_W	303_P	0.740	0.98
249_V	409_I	0.739	0.98
25_K	32_A	0.739	0.98
330_M	333_A	0.739	0.98
190_A	387_L	0.738	0.98
407_A	415_V	0.731	0.98
118_H	390_Y	0.731	0.98
365_E	368_E	0.731	0.98
246_V	313_D	0.731	0.98
320_R	333_A	0.730	0.98
298_D	302_A	0.730	0.98
156_I	184_G	0.728	0.98
173_Y	178_A	0.726	0.98
342_C	356_G	0.726	0.98
323_T	340_V	0.726	0.98
376_L	380_A	0.722	0.98
277_I	312_Y	0.722	0.98
136_I	249_V	0.721	0.98
56_I	60_A	0.720	0.98
18_I	45_G	0.718	0.98
382_K	385_A	0.717	0.98
330_M	362_H	0.716	0.98
326_K	342_C	0.715	0.98
324_S	338_D	0.715	0.98
336_R	339_V	0.714	0.97
60_A	92_I	0.712	0.97
229_V	359_E	0.711	0.97
103_I	108_H	0.711	0.97
343_A	357_G	0.710	0.97
361_I	370_R	0.709	0.97
400_L	405_T	0.708	0.97
123_S	126_Q	0.704	0.97
156_I	203_P	0.701	0.97
231_F	320_R	0.700	0.97
330_M	341_L	0.699	0.97
94_V	97_E	0.696	0.97
68_S	228_F	0.696	0.97
49_K	57_F	0.695	0.97
255_I	258_N	0.691	0.97
260_L	316_V	0.691	0.97
258_N	261_G	0.690	0.97
34_L	89_V	0.685	0.97
365_E	369_S	0.685	0.97
289_K	307_A	0.685	0.97
376_L	379_D	0.683	0.97
58_Q	62_S	0.682	0.97
271_K	274_F	0.680	0.97
254_K	261_G	0.680	0.97
159_G	187_Y	0.680	0.97
251_K	254_K	0.678	0.97
48_V	76_K	0.677	0.97
295_E	299_D	0.675	0.96
132_I	406_V	0.672	0.96
320_R	341_L	0.671	0.96
244_F	247_Q	0.671	0.96
263_D	269_Q	0.670	0.96
253_C	271_K	0.667	0.96
366_L	370_R	0.667	0.96
134_N	150_V	0.665	0.96
59_T	92_I	0.665	0.96
212_T	414_H	0.663	0.96
157_L	171_T	0.663	0.96
72_K	90_T	0.662	0.96
298_D	306_T	0.661	0.96
119_L	386_E	0.661	0.96
318_I	346_I	0.661	0.96
235_L	319_T	0.660	0.96
406_V	410_S	0.660	0.96
104_T	108_H	0.659	0.96
12_V	85_Y	0.656	0.96
299_D	304_H	0.655	0.96
162_P	183_S	0.649	0.96
101_Y	104_T	0.648	0.96
126_Q	417_E	0.647	0.96
114_M	417_E	0.645	0.95
77_E	80_R	0.644	0.95
238_Q	343_A	0.644	0.95
112_F	116_H	0.644	0.95
22_V	25_K	0.643	0.95
36_L	45_G	0.642	0.95
201_F	402_L	0.639	0.95
67_T	94_V	0.637	0.95
279_Y	283_I	0.637	0.95
154_P	200_S	0.636	0.95
56_I	92_I	0.636	0.95
410_S	418_T	0.635	0.95
299_D	302_A	0.634	0.95
120_W	123_S	0.633	0.95
39_G	196_G	0.630	0.95
311_H	411_G	0.629	0.95
242_V	400_L	0.629	0.95
287_K	308_I	0.629	0.95
144_F	237_V	0.625	0.95
45_G	69_L	0.625	0.95
326_K	358_S	0.624	0.95
298_D	305_E	0.623	0.95
302_A	307_A	0.623	0.95
302_A	305_E	0.622	0.95
277_I	281_E	0.622	0.95
237_V	240_N	0.622	0.95
108_H	125_R	0.622	0.95
132_I	260_L	0.621	0.94
13_G	77_E	0.620	0.94
235_L	317_F	0.619	0.94
321_Y	346_I	0.619	0.94
243_S	247_Q	0.618	0.94
341_L	359_E	0.618	0.94
47_V	92_I	0.617	0.94
137_I	153_D	0.616	0.94
257_L	315_P	0.614	0.94
345_L	400_L	0.613	0.94
153_D	220_W	0.613	0.94
25_K	65_Q	0.611	0.94
126_Q	129_I	0.611	0.94
289_K	303_P	0.610	0.94
308_I	312_Y	0.609	0.94
260_L	266_K	0.609	0.94
231_F	332_P	0.609	0.94
159_G	176_E	0.608	0.94
344_D	356_G	0.608	0.94
266_K	272_A	0.607	0.94
133_R	153_D	0.606	0.94
298_D	303_P	0.605	0.94
14_E	75_V	0.604	0.94
34_L	60_A	0.603	0.94
270_I	274_F	0.603	0.94
260_L	318_I	0.602	0.94
294_I	305_E	0.601	0.93
125_R	417_E	0.600	0.93
250_L	253_C	0.600	0.93
294_I	299_D	0.600	0.93
234_N	238_Q	0.599	0.93
230_E	359_E	0.596	0.93
352_G	408_W	0.594	0.93
124_K	127_H	0.592	0.93
210_S	424_L	0.590	0.93
362_H	392_S	0.589	0.93
247_Q	250_L	0.587	0.93
193_M	393_V	0.587	0.93
135_E	252_N	0.586	0.93
330_M	366_L	0.586	0.93
277_I	280_D	0.586	0.93
117_R	121_L	0.585	0.93
388_R	392_S	0.584	0.92
144_F	199_F	0.584	0.92
384_Y	388_R	0.582	0.92
232_E	235_L	0.582	0.92
40_T	131_K	0.581	0.92
246_V	270_I	0.580	0.92
160_S	179_Y	0.579	0.92
355_I	400_L	0.579	0.92
294_I	303_P	0.579	0.92
55_S	59_T	0.579	0.92
234_N	237_V	0.578	0.92
97_E	363_D	0.578	0.92
97_E	365_E	0.576	0.92
25_K	34_L	0.574	0.92
14_E	74_I	0.573	0.92
150_V	195_L	0.573	0.92
50_A	88_A	0.573	0.92
280_D	283_I	0.573	0.92
204_T	222_I	0.572	0.92
265_S	268_E	0.572	0.92
32_A	60_A	0.571	0.92
226_M	233_E	0.570	0.92
235_L	238_Q	0.570	0.92
276_R	279_Y	0.570	0.92
20_A	45_G	0.568	0.91
317_F	343_A	0.568	0.91
333_A	339_V	0.567	0.91
144_F	398_F	0.566	0.91
159_G	423_R	0.564	0.91
250_L	409_I	0.564	0.91
231_F	319_T	0.564	0.91
280_D	284_E	0.563	0.91
31_I	76_K	0.563	0.91
161_A	179_Y	0.562	0.91
282_A	285_F	0.561	0.91
154_P	184_G	0.561	0.91
235_L	259_T	0.559	0.91
275_P	278_T	0.559	0.91
295_E	301_G	0.559	0.91
296_W	302_A	0.559	0.91
186_L	384_Y	0.557	0.91
257_L	262_R	0.557	0.91
293_D	300_F	0.556	0.91
379_D	382_K	0.555	0.90
295_E	300_F	0.555	0.90
104_T	109_G	0.555	0.90
326_K	329_Y	0.555	0.90
133_R	403_E	0.554	0.90
147_E	244_F	0.554	0.90
28_S	32_A	0.554	0.90
188_M	192_A	0.553	0.90
98_A	390_Y	0.553	0.90
103_I	106_K	0.552	0.90
102_P	390_Y	0.549	0.90
270_I	283_I	0.549	0.90
386_E	390_Y	0.549	0.90
273_P	286_L	0.548	0.90
167_E	181_S	0.548	0.90
319_T	332_P	0.547	0.90
226_M	234_N	0.547	0.90
154_P	188_M	0.546	0.90
278_T	282_A	0.546	0.90
142_E	252_N	0.545	0.90
49_K	54_E	0.544	0.90
26_R	35_Q	0.544	0.90
234_N	343_A	0.542	0.89
149_F	184_G	0.542	0.89
412_A	415_V	0.541	0.89
305_E	308_I	0.541	0.89
298_D	304_H	0.540	0.89
103_I	112_F	0.539	0.89
304_H	308_I	0.537	0.89
269_Q	283_I	0.537	0.89
184_G	201_F	0.537	0.89
121_L	195_L	0.536	0.89
168_L	174_F	0.534	0.89
143_F	245_I	0.533	0.89
99_T	103_I	0.532	0.89
367_L	388_R	0.531	0.88
203_P	220_W	0.529	0.88
302_A	308_I	0.529	0.88
23_A	106_K	0.529	0.88
110_T	114_M	0.528	0.88
11_H	43_I	0.528	0.88
176_E	423_R	0.527	0.88
293_D	297_G	0.527	0.88
287_K	292_D	0.526	0.88
54_E	57_F	0.525	0.88
76_K	79_E	0.524	0.88
217_I	425_L	0.523	0.88
137_I	201_F	0.522	0.88
67_T	98_A	0.522	0.88
295_E	304_H	0.522	0.88
355_I	398_F	0.522	0.88
56_I	91_D	0.521	0.88
239_E	274_F	0.520	0.87
272_A	276_R	0.519	0.87
135_E	139_A	0.516	0.87
125_R	128_A	0.516	0.87
190_A	383_W	0.516	0.87
316_V	345_L	0.515	0.87
301_G	307_A	0.515	0.87
269_Q	272_A	0.514	0.87
304_H	318_I	0.514	0.87
19_G	95_I	0.513	0.87
149_F	234_N	0.510	0.86
65_Q	104_T	0.510	0.86
43_I	85_Y	0.510	0.86
257_L	260_L	0.509	0.86
260_L	263_D	0.508	0.86
300_F	305_E	0.508	0.86
75_V	86_E	0.506	0.86
28_S	79_E	0.506	0.86
296_W	304_H	0.506	0.86
27_S	31_I	0.505	0.86
231_F	359_E	0.504	0.86
256_E	261_G	0.504	0.86
285_F	312_Y	0.503	0.86
130_M	191_A	0.503	0.86
187_Y	204_T	0.502	0.86
136_I	405_T	0.502	0.86
234_N	357_G	0.501	0.85
68_S	95_I	0.501	0.85
259_T	263_D	0.500	0.85
287_K	291_F	0.500	0.85

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3i7fA	2	0.9442	100	0.156	Contact Map
1eovA	2	0.9907	100	0.17	Contact Map
2xgtA	2	0.9767	100	0.177	Contact Map
4j15A	2	0.8977	100	0.189	Contact Map
4up7A	2	0.9581	100	0.205	Contact Map
4ycuA	3	0.9791	100	0.206	Contact Map
4pg3A	2	0.9558	100	0.208	Contact Map
4ex5A	2	0.9535	100	0.208	Contact Map
1x54A	2	0.993	100	0.209	Contact Map
4wj4A	2	0.9791	100	0.212	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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