GREMLIN Database
ADEC - Adenine deaminase
UniProt: P39761 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 577 (559)
Sequences: 1524 (1131)
Seq/√Len: 47.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
23_I62_A4.9021.00
485_K504_S4.2561.00
485_K488_E4.0751.00
41_I67_I3.9111.00
471_A479_I3.7971.00
396_N574_I3.4441.00
151_K154_D3.4271.00
516_Q520_Q3.4131.00
396_N409_L3.3941.00
28_I39_E3.3711.00
475_N478_D3.3491.00
430_K476_D3.2301.00
95_H284_N3.2141.00
71_F337_V3.1551.00
284_N288_K3.1541.00
62_A330_F3.1431.00
455_S497_K3.0941.00
35_E234_R3.0391.00
343_M348_T2.9961.00
11_N16_R2.9901.00
332_S338_T2.9611.00
87_E90_K2.9401.00
26_G67_I2.8471.00
431_I560_M2.8061.00
170_V183_M2.7481.00
12_A49_V2.7021.00
382_K477_E2.6941.00
432_A479_I2.6421.00
557_D569_K2.6151.00
469_I483_V2.6141.00
263_R310_E2.5391.00
432_A471_A2.5381.00
399_Q449_K2.5351.00
459_A482_A2.5291.00
516_Q524_S2.5161.00
67_I328_L2.4771.00
145_R562_T2.4401.00
68_V331_V2.4301.00
27_K38_Y2.4191.00
489_I504_S2.4081.00
399_Q410_V2.3951.00
22_V56_G2.3621.00
26_G62_A2.3581.00
478_D499_G2.3481.00
67_I330_F2.3391.00
399_Q408_R2.2791.00
172_D175_S2.2561.00
448_V550_L2.2461.00
332_S340_T2.2291.00
23_I330_F2.2201.00
30_D33_N2.2121.00
124_R163_E2.2031.00
267_F290_A2.1501.00
117_E161_E2.1301.00
385_F483_V2.1221.00
408_R557_D2.0711.00
291_I337_V2.0411.00
279_S526_L2.0411.00
29_M68_V2.0180.99
412_V449_K2.0140.99
495_I531_K1.9840.99
65_Q340_T1.9400.99
423_D426_L1.9320.99
461_T469_I1.9220.99
567_D570_S1.9210.99
451_F472_V1.9140.99
121_E124_R1.9140.99
484_N487_Q1.9100.99
471_A483_V1.9040.99
287_V329_L1.8970.99
29_M36_W1.8960.99
333_D336_N1.8960.99
32_Y319_A1.8950.99
481_A485_K1.8770.99
382_K480_A1.8510.99
341_M348_T1.8430.99
27_K36_W1.8280.99
11_N17_Q1.8140.99
480_A484_N1.8030.99
301_Y337_V1.7840.99
320_I328_L1.7740.99
503_H531_K1.7610.99
28_I41_I1.7590.99
108_A116_I1.7460.99
376_L487_Q1.7260.98
134_L155_L1.7000.98
387_M447_V1.6930.98
233_I265_F1.6900.98
251_L293_A1.6790.98
350_A353_S1.6730.98
65_Q330_F1.6660.98
210_N235_R1.6540.98
486_L494_T1.6530.98
481_A499_G1.6460.98
145_R563_T1.6450.98
97_V282_S1.6450.98
251_L289_M1.6370.98
117_E121_E1.6200.98
374_V461_T1.6190.98
48_I328_L1.6020.97
409_L574_I1.6000.97
435_E441_K1.5960.97
60_I343_M1.5930.97
30_D35_E1.5900.97
301_Y305_S1.5890.97
8_N44_T1.5890.97
83_V521_V1.5870.97
25_N61_D1.5820.97
380_L480_A1.5810.97
330_F343_M1.5610.97
489_I494_T1.5540.97
20_D44_T1.5400.97
485_K489_I1.5400.97
187_L197_I1.5370.97
78_I130_I1.5360.97
14_A208_L1.5340.97
12_A44_T1.5280.96
143_F566_F1.5250.96
34_Q299_L1.5250.96
267_F283_V1.5160.96
30_D37_I1.5150.96
111_S510_A1.5120.96
496_I501_E1.5090.96
129_N317_K1.5040.96
434_V483_V1.4970.96
94_P350_A1.4940.96
397_V412_V1.4870.96
394_Q413_P1.4780.96
341_M351_E1.4670.96
34_Q302_Q1.4650.96
325_D345_K1.4580.95
160_E193_A1.4520.95
243_E251_L1.4510.95
74_G268_C1.4500.95
289_M293_A1.4340.95
508_P515_D1.4310.95
219_N311_C1.4240.95
49_V214_T1.4070.94
238_Y266_F1.4040.94
29_M301_Y1.3950.94
428_L447_V1.3940.94
21_I43_I1.3920.94
129_N345_K1.3920.94
23_I43_I1.3610.93
91_A518_A1.3580.93
392_E413_P1.3510.93
302_Q306_L1.3500.93
240_M268_C1.3400.93
65_Q332_S1.3390.93
230_L234_R1.3340.93
172_D180_E1.3340.93
553_P561_T1.3340.93
395_I447_V1.3340.93
8_N45_D1.3320.93
129_N344_V1.3280.92
374_V490_G1.3260.92
387_M445_L1.3260.92
396_N411_Q1.3250.92
287_V291_I1.3210.92
18_K55_E1.3210.92
133_M166_G1.3180.92
432_A445_L1.3150.92
429_L474_T1.3080.92
385_F480_A1.2970.92
117_E157_P1.2960.92
287_V304_G1.2940.91
247_A405_L1.2930.91
114_K117_E1.2890.91
558_I574_I1.2790.91
19_A42_A1.2730.91
18_K57_E1.2700.91
268_C312_Y1.2670.91
434_V461_T1.2640.90
486_L489_I1.2620.90
29_M298_F1.2490.90
156_K192_V1.2470.90
295_L303_L1.2430.90
145_R442_E1.2390.90
395_I414_A1.2390.90
222_E242_R1.2350.89
414_A447_V1.2330.89
566_F573_H1.2320.89
124_R161_E1.2290.89
434_V443_T1.2240.89
34_Q298_F1.2230.89
238_Y264_R1.2210.89
41_I320_I1.2210.89
455_S474_T1.2210.89
461_T483_V1.2140.89
123_A163_E1.2130.89
43_I328_L1.2080.88
29_M66_M1.1950.88
213_R237_M1.1940.88
509_I515_D1.1920.88
170_V175_S1.1900.88
32_Y324_F1.1900.88
117_E158_F1.1890.88
113_E158_F1.1800.87
494_T504_S1.1710.87
11_N179_A1.1690.87
459_A471_A1.1580.86
380_L385_F1.1580.86
238_Y310_E1.1560.86
506_P524_S1.1560.86
514_S521_V1.1530.86
264_R310_E1.1530.86
123_A126_T1.1530.86
289_M292_Q1.1520.86
331_V337_V1.1480.86
249_N252_N1.1430.85
268_C304_G1.1420.85
424_T429_L1.1400.85
42_A52_G1.1380.85
120_L163_E1.1370.85
478_D481_A1.1320.85
401_I408_R1.1310.85
409_L558_I1.1300.85
464_H467_H1.1300.85
328_L343_M1.1260.85
87_E518_A1.1250.84
485_K494_T1.1240.84
463_S470_I1.1220.84
473_G479_I1.1220.84
442_E562_T1.1210.84
92_V100_V1.1190.84
520_Q523_Q1.1180.84
331_V339_V1.1180.84
263_R302_Q1.1120.84
133_M165_L1.1090.84
287_V305_S1.1090.84
143_F573_H1.1090.84
486_L490_G1.1090.84
238_Y311_C1.1050.83
12_A19_A1.1020.83
140_A466_S1.1000.83
495_I535_I1.0990.83
283_V304_G1.0960.83
11_N14_A1.0940.83
26_G330_F1.0890.82
84_T509_I1.0850.82
43_I343_M1.0770.82
249_N404_Q1.0770.82
56_G59_I1.0740.82
470_I551_A1.0740.82
102_T132_F1.0670.81
8_N17_Q1.0670.81
175_S183_M1.0620.81
94_P128_L1.0620.81
209_I231_D1.0570.81
302_Q307_N1.0540.80
71_F329_L1.0510.80
517_S520_Q1.0500.80
240_M312_Y1.0490.80
144_E562_T1.0440.80
266_F311_C1.0440.80
219_N312_Y1.0420.80
291_I297_P1.0400.79
317_K325_D1.0350.79
107_I115_G1.0350.79
100_V128_L1.0340.79
36_W334_L1.0320.79
431_I446_G1.0260.79
68_V329_L1.0230.78
482_A496_I1.0220.78
21_I60_I1.0210.78
24_K59_I1.0180.78
26_G328_L1.0170.78
39_E51_L1.0170.78
503_H527_T1.0170.78
13_S211_I1.0170.78
219_N268_C1.0150.78
257_V303_L1.0130.78
319_A324_F1.0100.77
316_T325_D1.0100.77
410_V449_K1.0070.77
383_Q386_H1.0060.77
333_D338_T1.0040.77
37_I234_R1.0040.77
472_V547_L1.0040.77
297_P300_A1.0000.77
33_N234_R0.9990.77
226_K256_A0.9960.76
434_V469_I0.9950.76
22_V54_Y0.9940.76
22_V42_A0.9930.76
206_T231_D0.9920.76
229_A256_A0.9910.76
174_V571_F0.9910.76
431_I472_V0.9840.76
417_A421_E0.9810.75
159_Y195_K0.9800.75
76_V269_T0.9780.75
134_L158_F0.9770.75
254_L295_L0.9750.75
76_V88_F0.9740.75
28_I51_L0.9710.75
348_T351_E0.9710.75
448_V451_F0.9700.74
394_Q411_Q0.9630.74
36_W66_M0.9630.74
385_F479_I0.9580.74
432_A483_V0.9580.74
523_Q527_T0.9540.73
99_T131_H0.9530.73
129_N325_D0.9450.73
185_Q189_D0.9450.73
372_D490_G0.9450.73
25_N63_E0.9440.72
226_K230_L0.9410.72
470_I560_M0.9400.72
179_A184_V0.9390.72
89_A127_P0.9380.72
23_I343_M0.9370.72
176_V187_L0.9370.72
156_K189_D0.9370.72
202_A232_R0.9360.72
15_K207_D0.9340.72
228_E231_D0.9330.72
113_E157_P0.9320.71
435_E440_L0.9320.71
41_I51_L0.9310.71
48_I51_L0.9280.71
389_I416_V0.9260.71
262_A299_L0.9240.71
67_I320_I0.9230.71
31_V319_A0.9180.70
431_I550_L0.9180.70
172_D183_M0.9150.70
81_S88_F0.9150.70
29_M334_L0.9110.70
105_H171_M0.9110.70
385_F432_A0.9090.70
205_S231_D0.9090.70
171_M554_V0.9060.69
295_L300_A0.9040.69
105_H467_H0.8970.69
131_H165_L0.8960.68
423_D427_D0.8960.68
105_H464_H0.8940.68
74_G308_A0.8930.68
119_M513_L0.8930.68
159_Y189_D0.8900.68
566_F571_F0.8900.68
93_L128_L0.8890.68
459_A483_V0.8870.68
291_I301_Y0.8870.68
106_E464_H0.8850.68
22_V59_I0.8800.67
70_G98_T0.8800.67
287_V301_Y0.8770.67
460_T548_S0.8760.67
24_K40_D0.8750.67
524_S527_T0.8750.67
240_M266_F0.8740.67
340_T352_D0.8720.66
12_A17_Q0.8720.66
100_V130_I0.8680.66
159_Y245_S0.8660.66
481_A501_E0.8640.66
21_I343_M0.8620.65
351_E354_K0.8610.65
306_L310_E0.8590.65
42_A50_G0.8580.65
458_I532_L0.8580.65
251_L292_Q0.8570.65
405_L555_I0.8540.65
74_G312_Y0.8530.65
107_I119_M0.8510.64
80_S467_H0.8510.64
455_S498_N0.8500.64
97_V545_L0.8500.64
22_V40_D0.8480.64
137_S175_S0.8480.64
241_M267_F0.8470.64
106_E467_H0.8460.64
114_K369_A0.8460.64
485_K501_E0.8460.64
58_N348_T0.8450.64
283_V286_Q0.8450.64
86_I122_Q0.8450.64
123_A130_I0.8440.64
137_S171_M0.8410.64
111_S370_L0.8400.63
448_V472_V0.8400.63
116_I134_L0.8370.63
188_L192_V0.8360.63
116_I158_F0.8340.63
10_L179_A0.8330.63
235_R322_P0.8320.63
184_V187_L0.8320.63
475_N479_I0.8320.63
560_M565_L0.8310.63
481_A496_I0.8280.62
88_F100_V0.8250.62
224_T406_E0.8250.62
247_A549_F0.8210.62
118_F122_Q0.8210.62
58_N347_Q0.8200.62
30_D319_A0.8200.62
530_D534_L0.8180.61
92_V128_L0.8180.61
497_K502_L0.8170.61
462_I512_L0.8170.61
80_S271_D0.8140.61
80_S105_H0.8120.61
66_M334_L0.8110.61
464_H552_L0.8090.60
456_G478_D0.8080.60
62_A67_I0.8070.60
532_L535_I0.8050.60
101_V312_Y0.8020.60
111_S115_G0.8020.60
126_T130_I0.8010.60
80_S464_H0.8000.60
196_R311_C0.7990.60
156_K193_A0.7980.59
16_R231_D0.7950.59
423_D447_V0.7940.59
282_S545_L0.7920.59
429_L472_V0.7900.59
134_L164_V0.7900.59
379_P488_E0.7870.58
508_P514_S0.7850.58
155_L159_Y0.7820.58
531_K534_L0.7810.58
27_K66_M0.7810.58
379_P487_Q0.7780.57
239_V256_A0.7770.57
459_A486_L0.7760.57
505_V521_V0.7760.57
99_T316_T0.7750.57
150_L155_L0.7730.57
263_R307_N0.7680.57
9_R49_V0.7680.57
74_G240_M0.7680.57
458_I495_I0.7670.56
36_W298_F0.7640.56
245_S312_Y0.7620.56
427_D452_G0.7620.56
229_A239_V0.7620.56
206_T209_I0.7610.56
106_E552_L0.7580.56
145_R440_L0.7540.55
241_M254_L0.7540.55
267_F304_G0.7510.55
412_V428_L0.7500.55
291_I333_D0.7490.55
532_L542_N0.7480.55
467_H552_L0.7450.54
159_Y190_A0.7420.54
76_V81_S0.7400.54
375_K438_K0.7390.54
146_S466_S0.7390.54
405_L559_K0.7380.54
243_E289_M0.7380.54
88_F282_S0.7370.53
466_S553_P0.7370.53
131_H317_K0.7350.53
536_G543_P0.7340.53
205_S241_M0.7330.53
89_A126_T0.7240.52
28_I328_L0.7230.52
203_G406_E0.7230.52
401_I404_Q0.7230.52
108_A220_D0.7220.52
502_L535_I0.7220.52
520_Q524_S0.7220.52
59_I63_E0.7220.52
40_D56_G0.7200.52
78_I85_P0.7190.52
153_A185_Q0.7160.51
72_I101_V0.7150.51
95_H339_V0.7130.51
347_Q354_K0.7120.51
72_I309_A0.7080.51
157_P160_E0.7070.50
209_I235_R0.7060.50
109_N147_G0.7060.50
314_L317_K0.7060.50
445_L476_D0.7050.50
106_E110_V0.7030.50
498_N501_E0.7020.50
60_I348_T0.7020.50
102_T168_A0.6970.49
269_T495_I0.6950.49
136_S464_H0.6940.49
105_H552_L0.6940.49
274_V545_L0.6930.49
182_D186_K0.6930.49
120_L132_F0.6920.49
136_S467_H0.6920.49
272_K286_Q0.6910.49
414_A423_D0.6900.49
88_F92_V0.6890.49
54_Y59_I0.6890.49
280_E285_H0.6880.49
479_I483_V0.6880.49
255_P293_A0.6880.49
155_L189_D0.6870.48
209_I213_R0.6870.48
72_I308_A0.6870.48
17_Q44_T0.6860.48
267_F286_Q0.6860.48
171_M467_H0.6850.48
80_S106_E0.6850.48
266_F308_A0.6840.48
81_S92_V0.6830.48
136_S167_L0.6830.48
321_A324_F0.6820.48
505_V524_S0.6820.48
416_V419_E0.6820.48
412_V426_L0.6810.48
136_S171_M0.6800.48
478_D498_N0.6800.48
424_T474_T0.6780.48
154_D157_P0.6770.47
291_I332_S0.6760.47
16_R179_A0.6750.47
71_F305_S0.6720.47
9_R12_A0.6700.47
181_K185_Q0.6690.47
109_N467_H0.6650.46
389_I420_F0.6640.46
271_D467_H0.6640.46
177_Q211_I0.6630.46
427_D474_T0.6630.46
201_L232_R0.6620.46
31_V302_Q0.6620.46
79_E271_D0.6610.46
427_D450_G0.6600.46
80_S171_M0.6600.46
219_N240_M0.6600.46
444_G560_M0.6590.46
106_E465_D0.6570.45
239_V265_F0.6540.45
339_V342_T0.6540.45
98_T269_T0.6540.45
120_L161_E0.6520.45
301_Y331_V0.6520.45
223_V228_E0.6510.45
446_G560_M0.6500.45
213_R235_R0.6490.45
144_E553_P0.6490.45
423_D428_L0.6480.45
70_G305_S0.6480.45
109_N139_P0.6470.44
463_S551_A0.6470.44
109_N464_H0.6470.44
189_D193_A0.6470.44
85_P365_A0.6470.44
396_N558_I0.6460.44
232_R239_V0.6460.44
296_N299_L0.6460.44
291_I339_V0.6460.44
315_D324_F0.6460.44
23_I67_I0.6430.44
451_F460_T0.6420.44
42_A56_G0.6420.44
330_F340_T0.6420.44
20_D57_E0.6410.44
29_M331_V0.6400.44
398_I407_T0.6390.44
299_L302_Q0.6380.44
76_V282_S0.6380.44
99_T129_N0.6360.43
462_I493_L0.6340.43
461_T489_I0.6340.43
195_K509_I0.6330.43
74_G463_S0.6310.43
141_A466_S0.6310.43
182_D185_Q0.6300.43
105_H109_N0.6300.43
171_M464_H0.6290.43
70_G327_D0.6280.43
268_C283_V0.6270.42
23_I142_S0.6260.42
80_S552_L0.6240.42
137_S554_V0.6240.42
48_I320_I0.6240.42
88_F559_K0.6240.42
79_E105_H0.6240.42
271_D464_H0.6230.42
488_E504_S0.6230.42
31_V298_F0.6220.42
429_L448_V0.6200.42
527_T531_K0.6190.42
107_I510_A0.6180.42
44_T49_V0.6160.41
83_V518_A0.6160.41
409_L567_D0.6130.41
79_E552_L0.6120.41
301_Y334_L0.6120.41
249_N253_V0.6120.41
275_D542_N0.6100.41
82_M273_H0.6100.41
183_M186_K0.6100.41
210_N322_P0.6100.41
105_H554_V0.6080.41
233_I239_V0.6080.41
227_E231_D0.6070.41
530_D533_S0.6060.40
89_A123_A0.6050.40
433_V562_T0.6040.40
138_V171_M0.6040.40
113_E154_D0.6030.40
105_H139_P0.6030.40
28_I36_W0.6020.40
514_S524_S0.6020.40
140_A171_M0.6000.40
243_E248_K0.6000.40
272_K283_V0.5990.40
80_S136_S0.5980.40
414_A428_L0.5980.40
82_M462_I0.5980.40
350_A355_A0.5980.40
168_A404_Q0.5960.39
197_I217_V0.5960.39
508_P516_Q0.5950.39
50_G56_G0.5950.39
297_P301_Y0.5940.39
371_L515_D0.5930.39
305_S309_A0.5910.39
106_E271_D0.5910.39
397_V410_V0.5910.39
450_G561_T0.5890.39
71_F339_V0.5890.39
277_L282_S0.5890.39
30_D324_F0.5880.39
233_I295_L0.5870.39
427_D449_K0.5870.39
380_L483_V0.5870.39
105_H136_S0.5860.38
381_N384_D0.5860.38
186_K549_F0.5860.38
422_P476_D0.5840.38
83_V274_V0.5840.38
82_M507_L0.5830.38
105_H137_S0.5820.38
254_L257_V0.5820.38
109_N552_L0.5800.38
532_L537_F0.5800.38
240_M311_C0.5790.38
138_V467_H0.5790.38
155_L187_L0.5780.38
395_I422_P0.5780.38
348_T390_D0.5780.38
141_A553_P0.5780.38
38_Y63_E0.5780.38
329_L339_V0.5770.38
108_A150_L0.5770.38
247_A273_H0.5760.38
380_L434_V0.5760.38
417_A524_S0.5760.38
210_N284_N0.5760.38
165_L176_V0.5760.38
477_E499_G0.5750.37
262_A303_L0.5750.37
201_L204_L0.5740.37
305_S308_A0.5710.37
172_D447_V0.5710.37
244_G430_K0.5710.37
79_E464_H0.5700.37
201_L206_T0.5700.37
201_L228_E0.5700.37
246_V249_N0.5680.37
226_K229_A0.5680.37
271_D468_N0.5680.37
153_A530_D0.5680.37
68_V71_F0.5680.37
138_V552_L0.5670.37
73_D282_S0.5670.37
229_A305_S0.5660.37
84_T374_V0.5650.37
71_F331_V0.5650.37
302_Q305_S0.5650.37
110_V437_H0.5650.37
405_L549_F0.5650.37
79_E467_H0.5650.37
416_V420_F0.5640.36
249_N551_A0.5640.36
50_G54_Y0.5630.36
14_A211_I0.5630.36
434_V471_A0.5630.36
291_I306_L0.5630.36
158_F161_E0.5620.36
9_R45_D0.5620.36
137_S172_D0.5610.36
81_S219_N0.5610.36
108_A158_F0.5610.36
202_A545_L0.5610.36
60_I341_M0.5610.36
141_A202_A0.5590.36
97_V202_A0.5590.36
228_E433_V0.5590.36
385_F471_A0.5590.36
65_Q331_V0.5590.36
288_K339_V0.5580.36
225_S228_E0.5580.36
529_H542_N0.5580.36
232_R420_F0.5570.36
241_M289_M0.5570.36
269_T286_Q0.5570.36
43_I330_F0.5560.36
364_A367_D0.5540.36
271_D465_D0.5540.36
79_E106_E0.5530.35
109_N171_M0.5530.35
291_I335_E0.5530.35
287_V337_V0.5520.35
219_N566_F0.5510.35
137_S466_S0.5510.35
198_D219_N0.5510.35
533_S572_Q0.5500.35
71_F295_L0.5490.35
202_A206_T0.5480.35
258_N261_N0.5480.35
105_H465_D0.5480.35
19_A22_V0.5480.35
81_S271_D0.5470.35
68_V320_I0.5470.35
219_N239_V0.5460.35
89_A514_S0.5460.35
355_A359_D0.5460.35
68_V301_Y0.5450.35
495_I528_L0.5450.35
374_V486_L0.5450.35
106_E171_M0.5440.35
105_H138_V0.5440.35
134_L159_Y0.5440.35
355_A358_Q0.5430.34
262_A302_Q0.5430.34
42_A54_Y0.5420.34
122_Q125_H0.5420.34
331_V340_T0.5410.34
106_E136_S0.5410.34
171_M552_L0.5410.34
122_Q211_I0.5410.34
223_V249_N0.5410.34
146_S155_L0.5400.34
233_I264_R0.5400.34
175_S180_E0.5390.34
222_E244_G0.5390.34
500_E523_Q0.5390.34
227_E413_P0.5380.34
133_M198_D0.5380.34
58_N351_E0.5370.34
50_G210_N0.5360.34
265_F303_L0.5350.34
139_P467_H0.5340.34
198_D549_F0.5340.34
48_I348_T0.5340.34
30_D268_C0.5330.34
298_F301_Y0.5320.34
502_L531_K0.5320.34
47_V315_D0.5320.34
461_T482_A0.5320.34
271_D552_L0.5310.33
256_A265_F0.5300.33
475_N498_N0.5290.33
246_V266_F0.5290.33
495_I544_F0.5270.33
528_L539_G0.5270.33
477_E481_A0.5270.33
109_N271_D0.5270.33
275_D526_L0.5260.33
432_A480_A0.5260.33
139_P464_H0.5260.33
12_A214_T0.5250.33
106_E109_N0.5250.33
480_A487_Q0.5250.33
285_H288_K0.5250.33
42_A210_N0.5250.33
118_F121_E0.5240.33
255_P258_N0.5230.33
292_Q425_E0.5220.33
97_V461_T0.5220.33
187_L190_A0.5210.33
92_V137_S0.5210.33
115_G510_A0.5210.33
233_I256_A0.5210.33
252_N255_P0.5200.32
100_V495_I0.5200.32
514_S517_S0.5190.32
16_R177_Q0.5190.32
437_H552_L0.5190.32
29_M337_V0.5180.32
185_Q535_I0.5180.32
105_H271_D0.5170.32
105_H110_V0.5170.32
90_K126_T0.5170.32
322_P558_I0.5160.32
171_M175_S0.5160.32
43_I225_S0.5160.32
167_L554_V0.5160.32
93_L350_A0.5150.32
227_E498_N0.5150.32
18_K59_I0.5140.32
414_A420_F0.5140.32
71_F308_A0.5140.32
43_I287_V0.5140.32
23_I328_L0.5140.32
550_L559_K0.5140.32
241_M253_V0.5140.32
81_S468_N0.5130.32
41_I345_K0.5130.32
379_P484_N0.5130.32
147_G467_H0.5120.32
231_D235_R0.5120.32
93_L344_V0.5120.32
177_Q239_V0.5110.32
351_E358_Q0.5100.32
19_A49_V0.5100.32
196_R308_A0.5100.32
468_N552_L0.5090.31
467_H554_V0.5080.31
30_D235_R0.5080.31
23_I143_F0.5060.31
429_L537_F0.5050.31
278_L519_E0.5050.31
171_M465_D0.5050.31
109_N468_N0.5040.31
97_V127_P0.5040.31
71_F269_T0.5040.31
292_Q336_N0.5040.31
424_T449_K0.5030.31
203_G225_S0.5030.31
231_D276_D0.5030.31
292_Q530_D0.5030.31
104_P171_M0.5020.31
83_V273_H0.5020.31
51_L298_F0.5020.31
258_N295_L0.5010.31
356_V359_D0.5010.31
213_R322_P0.5010.31
248_K533_S0.5010.31
278_L522_N0.5000.31
140_A554_V0.5000.31
151_K182_D0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3nqbA 2 0.9827 100 0.312 Contact Map
2vunA 3 0.5789 100 0.797 Contact Map
2icsA 1 0.5581 100 0.797 Contact Map
2ogjA 4 0.5737 100 0.804 Contact Map
3be7A 5 0.5633 100 0.807 Contact Map
3mtwA 5 0.5615 100 0.808 Contact Map
4whbE 3 0.5893 100 0.809 Contact Map
3lnpA 2 0.5962 100 0.811 Contact Map
4c65A 6 0.5823 100 0.813 Contact Map
4cqbA 2 0.5685 100 0.813 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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