GREMLIN Database
FLIT - Flagellar protein FliT
UniProt: P39740 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 113 (112)
Sequences: 131 (112)
Seq/√Len: 10.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
64_D108_Y3.8510.99
75_K79_A3.8100.99
39_S43_Q2.4270.83
18_I83_Q2.2170.77
25_D109_Y2.1850.76
18_I90_V2.0140.70
74_L85_M1.9890.69
60_I63_W1.9100.66
64_D68_V1.7880.60
4_I111_K1.7870.60
23_E112_R1.7850.60
88_K109_Y1.7840.60
29_K65_Q1.7590.59
14_M34_F1.6670.55
17_H77_S1.5880.51
75_K109_Y1.5850.51
50_S53_E1.5710.50
18_I33_D1.5650.50
30_Q42_I1.5420.49
45_I107_T1.5110.47
25_D108_Y1.5090.47
33_D51_E1.4750.46
25_D92_H1.4540.45
28_L63_W1.4140.43
11_T36_A1.4020.42
14_M89_R1.4020.42
22_P108_Y1.3740.41
11_T86_K1.3670.41
37_T54_R1.3670.41
17_H35_V1.3650.41
14_M24_S1.3460.40
61_L108_Y1.3210.39
53_E60_I1.3190.39
13_S52_E1.3020.38
25_D85_M1.2610.36
2_N63_W1.2580.36
12_K59_L1.2580.36
64_D94_T1.2470.35
4_I59_L1.2330.35
74_L104_I1.2230.34
78_I81_E1.2170.34
67_I102_I1.2110.34
8_Y63_W1.1800.33
11_T54_R1.1700.32
31_I61_L1.1660.32
26_E44_E1.1610.32
7_L17_H1.1400.31
57_M108_Y1.1390.31
49_L57_M1.1130.30
35_V112_R1.1040.29
5_D86_K1.1020.29
24_S108_Y1.0950.29
4_I32_E1.0890.29
11_T47_L1.0880.29
24_S81_E1.0870.29
87_R112_R1.0590.28
17_H27_L1.0480.27
30_Q34_F1.0460.27
100_N103_T1.0440.27
48_P53_E1.0160.26
38_R110_D1.0160.26
38_R95_Y1.0160.26
95_Y110_D1.0160.26
9_T82_L1.0140.26
7_L10_E1.0080.26
2_N111_K1.0060.26
81_E94_T0.9950.25
75_K78_I0.9930.25
57_M63_W0.9880.25
46_S61_L0.9820.25
22_P27_L0.9740.25
40_E69_K0.9680.24
51_E55_K0.9640.24
92_H108_Y0.9600.24
77_S80_T0.9580.24
34_F43_Q0.9470.24
71_M81_E0.9420.24
24_S28_L0.9320.23
45_I48_P0.9290.23
42_I64_D0.8930.22
100_N104_I0.8930.22
15_L82_L0.8900.22
71_M78_I0.8850.22
52_E99_Y0.8780.21
49_L107_T0.8720.21
49_L92_H0.8510.21
52_E58_K0.8450.20
7_L103_T0.8260.20
60_I94_T0.8080.19
39_S62_T0.8050.19
28_L81_E0.8020.19
75_K102_I0.8020.19
95_Y106_G0.8010.19
38_R106_G0.8010.19
106_G110_D0.8010.19
78_I109_Y0.7940.19
28_L97_N0.7930.19
71_M80_T0.7830.19
73_R93_T0.7730.18
17_H75_K0.7550.18
28_L43_Q0.7530.18
48_P98_P0.7510.18
35_V71_M0.7500.18
89_R93_T0.7370.17
42_I102_I0.7360.17
21_T96_L0.7340.17
37_T60_I0.7290.17
67_I111_K0.7220.17
8_Y64_D0.7180.17
43_Q51_E0.7140.17
46_S107_T0.7120.17
19_Q65_Q0.7110.17
53_E59_L0.7070.17
9_T12_K0.7050.16
7_L36_A0.7040.16
22_P74_L0.7040.16
35_V60_I0.7030.16
67_I74_L0.7020.16
14_M36_A0.6980.16
5_D56_Q0.6980.16
9_T32_E0.6970.16
11_T48_P0.6910.16
32_E109_Y0.6870.16
29_K73_R0.6860.16
13_S34_F0.6780.16
3_N41_L0.6770.16
86_K108_Y0.6660.15
74_L80_T0.6640.15
4_I63_W0.6630.15
62_T72_E0.6550.15
17_H71_M0.6490.15
31_I63_W0.6460.15
67_I79_A0.6400.15
72_E101_N0.6390.15
96_L100_N0.6230.14
28_L83_Q0.6210.14
12_K54_R0.6170.14
60_I66_L0.6130.14
32_E55_K0.6080.14
35_V104_I0.6000.14
28_L51_E0.5980.14
23_E74_L0.5920.14
7_L42_I0.5870.14
51_E54_R0.5810.14
79_A108_Y0.5750.13
2_N8_Y0.5740.13
49_L100_N0.5720.13
51_E107_T0.5680.13
50_S65_Q0.5540.13
41_L44_E0.5500.13
93_T100_N0.5480.13
17_H22_P0.5440.13
63_W90_V0.5330.12
70_E74_L0.5310.12
18_I67_I0.5290.12
15_L67_I0.5280.12
59_L90_V0.5240.12
78_I88_K0.5230.12
68_V88_K0.5190.12
14_M67_I0.5190.12
33_D37_T0.5180.12
7_L111_K0.5170.12
79_A101_N0.5170.12
36_A86_K0.5150.12
7_L49_L0.5030.12
29_K93_T0.5030.12
34_F100_N0.5000.12
63_W83_Q0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2fztA 2 0.6903 91.8 0.86 Contact Map
3h3mA 2 0.6814 80.2 0.883 Contact Map
3a7mA 2 0.9027 70.4 0.892 Contact Map
3nkzA 4 0.6903 53.4 0.903 Contact Map
4kf8A 1 0.6726 41.2 0.91 Contact Map
1vt0M 4 0.5398 35.2 0.913 Contact Map
5ajdB 1 0.1416 25.9 0.919 Contact Map
3gn4A 1 0.531 20.4 0.923 Contact Map
3nmdA 2 0.4779 17.8 0.925 Contact Map
4uqzB 1 0 10.9 0.932 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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