COMEC - BACSU - GREMLIN Contacts

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COMEC - ComE operon protein 3

UniProt:	P39695	Sequences: MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQFKAVIDTIPKIDGDRMSMMVETPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHIHWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSTGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHVGILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVRSATAICLSYIVLLLFNPYHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGAVAGVLLLSLSASFGRLFFSWFDLLISWINRLITNIADVDVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGGICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKGIKQLDALILTHADQDHIGEAEILLKHHKVKRLVIPKGFVSEPKDEKVLQAAREEGVAIEEVKRGDVLQIKDLQFHVLSPEAPDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMNVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKNNRYHHPHQKVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	776 (723)
Sequences:	2632 (2275)
Seq/√Len:	84.6

ECOLI - YCAI
BACSU - COMEC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
691_V	713_A	6.437	1.00
503_M	714_I	5.751	1.00
649_N	670_E	5.098	1.00
669_L	673_G	5.040	1.00
686_A	708_L	4.426	1.00
669_L	692_G	4.212	1.00
567_L	580_A	4.186	1.00
135_G	164_Y	4.017	1.00
524_L	564_L	3.793	1.00
712_T	742_L	3.630	1.00
513_F	524_L	3.491	1.00
149_F	154_Y	3.455	1.00
706_Q	737_H	3.427	1.00
504_I	513_F	3.412	1.00
145_V	749_T	3.395	1.00
655_W	662_S	3.383	1.00
525_I	665_L	3.292	1.00
563_Q	590_K	3.240	1.00
713_A	739_I	3.239	1.00
146_P	749_T	3.188	1.00
151_Y	155_L	3.172	1.00
715_I	741_V	3.124	1.00
655_W	686_A	3.106	1.00
510_D	690_K	3.088	1.00
500_E	515_G	3.077	1.00
692_G	734_L	3.042	1.00
717_A	743_R	3.004	1.00
700_T	734_L	2.934	1.00
82_A	99_V	2.910	1.00
591_R	619_E	2.753	1.00
273_V	286_A	2.751	1.00
266_L	290_G	2.743	1.00
515_G	559_K	2.702	1.00
503_M	512_M	2.700	1.00
697_K	727_H	2.638	1.00
671_K	701_G	2.617	1.00
501_V	663_W	2.587	1.00
194_N	206_Q	2.567	1.00
522_R	564_L	2.506	1.00
691_V	734_L	2.479	1.00
546_S	582_I	2.446	1.00
717_A	745_D	2.400	1.00
566_A	591_R	2.387	1.00
312_Y	328_F	2.381	1.00
691_V	715_I	2.348	1.00
687_D	711_K	2.329	1.00
140_P	155_L	2.304	1.00
513_F	555_F	2.285	1.00
705_I	739_I	2.264	1.00
697_K	729_K	2.231	1.00
627_L	634_F	2.229	1.00
337_S	365_G	2.224	1.00
670_E	673_G	2.221	1.00
663_W	688_V	2.215	1.00
635_H	655_W	2.214	1.00
564_L	567_L	2.203	1.00
81_K	132_E	2.202	1.00
247_L	268_F	2.183	1.00
516_A	630_K	2.181	1.00
502_D	749_T	2.178	1.00
329_Q	373_H	2.143	1.00
712_T	752_Y	2.130	1.00
584_L	589_V	2.130	1.00
224_Y	429_N	2.127	1.00
649_N	672_E	2.114	1.00
626_V	635_H	2.113	1.00
715_I	734_L	2.109	1.00
14_S	21_A	2.050	1.00
651_S	667_G	2.034	1.00
525_I	570_T	2.033	1.00
592_L	611_A	2.026	1.00
702_E	706_Q	2.024	1.00
338_L	358_V	2.016	1.00
649_N	673_G	2.005	1.00
147_G	558_A	1.997	1.00
662_S	687_D	1.983	1.00
635_H	657_E	1.971	1.00
315_L	322_H	1.965	1.00
704_F	708_L	1.955	1.00
410_S	413_F	1.947	1.00
234_A	281_S	1.944	1.00
684_I	708_L	1.931	1.00
521_G	565_D	1.911	1.00
670_E	701_G	1.900	1.00
523_V	568_I	1.865	1.00
527_T	580_A	1.864	1.00
553_I	587_H	1.850	1.00
511_S	552_L	1.826	1.00
513_F	561_I	1.818	1.00
714_I	752_Y	1.803	1.00
655_W	708_L	1.797	1.00
674_E	700_T	1.788	1.00
728_Q	732_Q	1.785	1.00
692_G	700_T	1.780	1.00
333_A	369_I	1.778	1.00
17_A	20_T	1.776	1.00
304_S	339_I	1.771	1.00
315_L	332_F	1.767	1.00
513_F	522_R	1.765	1.00
718_G	721_N	1.762	1.00
674_E	699_S	1.759	1.00
502_D	751_Q	1.746	1.00
743_R	746_Q	1.743	1.00
628_Q	633_Q	1.741	1.00
529_G	547_L	1.738	1.00
731_L	741_V	1.737	1.00
653_V	669_L	1.703	1.00
311_S	332_F	1.702	1.00
570_T	652_L	1.700	1.00
274_M	278_A	1.692	1.00
552_L	583_L	1.691	1.00
514_V	656_M	1.690	1.00
713_A	734_L	1.682	1.00
81_K	130_S	1.680	1.00
403_G	418_F	1.679	1.00
705_I	733_L	1.668	1.00
273_V	282_V	1.668	1.00
700_T	705_I	1.661	1.00
54_S	57_L	1.660	1.00
395_C	424_L	1.656	1.00
512_M	665_L	1.652	1.00
376_Q	557_T	1.648	1.00
508_Q	721_N	1.641	1.00
499_G	658_T	1.636	1.00
626_V	633_Q	1.635	1.00
689_L	734_L	1.633	1.00
655_W	684_I	1.633	1.00
523_V	566_A	1.626	1.00
513_F	564_L	1.622	1.00
634_F	656_M	1.613	1.00
716_S	744_T	1.610	1.00
234_A	285_A	1.603	1.00
508_Q	718_G	1.600	1.00
287_L	311_S	1.595	1.00
53_F	56_I	1.594	1.00
548_G	583_L	1.592	1.00
689_L	705_I	1.589	1.00
555_F	559_K	1.584	1.00
636_V	654_L	1.572	1.00
371_L	445_I	1.570	1.00
500_E	753_R	1.570	1.00
568_I	636_V	1.556	1.00
657_E	662_S	1.548	1.00
705_I	737_H	1.547	1.00
312_Y	332_F	1.546	1.00
502_D	515_G	1.541	1.00
499_G	754_Y	1.540	1.00
529_G	574_Q	1.538	1.00
681_F	684_I	1.534	1.00
245_A	249_Y	1.530	1.00
213_R	285_A	1.523	1.00
230_V	234_A	1.522	1.00
573_D	647_K	1.522	1.00
569_L	577_I	1.511	0.99
283_L	315_L	1.507	0.99
524_L	567_L	1.505	0.99
190_I	212_D	1.500	0.99
213_R	234_A	1.498	0.99
666_T	692_G	1.493	0.99
12_A	15_A	1.489	0.99
140_P	163_N	1.486	0.99
675_Q	703_E	1.483	0.99
702_E	737_H	1.479	0.99
508_Q	725_H	1.476	0.99
83_V	130_S	1.472	0.99
514_V	523_V	1.463	0.99
403_G	421_F	1.462	0.99
566_A	593_V	1.460	0.99
266_L	293_L	1.457	0.99
501_V	752_Y	1.457	0.99
503_M	690_K	1.451	0.99
232_L	388_M	1.440	0.99
18_G	21_A	1.438	0.99
710_P	739_I	1.438	0.99
553_I	586_H	1.429	0.99
698_G	730_V	1.424	0.99
53_F	57_L	1.416	0.99
624_G	639_P	1.415	0.99
678_M	707_Q	1.414	0.99
341_S	361_I	1.406	0.99
633_Q	657_E	1.399	0.99
57_L	66_D	1.389	0.99
396_I	424_L	1.386	0.99
308_I	312_Y	1.383	0.99
14_S	20_T	1.381	0.99
20_T	25_F	1.379	0.99
742_L	750_I	1.373	0.99
80_F	135_G	1.371	0.99
636_V	639_P	1.370	0.99
568_I	654_L	1.366	0.99
689_L	710_P	1.359	0.99
569_L	580_A	1.358	0.99
521_G	630_K	1.353	0.99
17_A	21_A	1.351	0.99
527_T	578_G	1.340	0.99
11_A	14_S	1.329	0.99
515_G	522_R	1.328	0.99
201_S	422_D	1.325	0.99
553_I	583_L	1.321	0.99
54_S	58_F	1.319	0.99
684_I	704_F	1.319	0.99
279_A	282_V	1.318	0.99
240_V	286_A	1.318	0.99
13_A	16_T	1.316	0.99
548_G	551_V	1.314	0.99
240_V	269_L	1.313	0.99
646_S	670_E	1.308	0.99
61_L	65_T	1.307	0.99
527_T	567_L	1.306	0.99
115_S	135_G	1.305	0.99
565_D	590_K	1.302	0.98
500_E	751_Q	1.301	0.98
273_V	278_A	1.300	0.98
499_G	517_P	1.296	0.98
691_V	741_V	1.294	0.98
621_V	652_L	1.288	0.98
326_A	373_H	1.284	0.98
82_A	133_L	1.282	0.98
232_L	389_V	1.282	0.98
15_A	18_G	1.277	0.98
384_M	435_I	1.276	0.98
714_I	750_I	1.273	0.98
28_I	32_I	1.273	0.98
79_Q	134_T	1.268	0.98
670_E	692_G	1.260	0.98
504_I	555_F	1.255	0.98
239_H	396_I	1.255	0.98
143_A	150_D	1.248	0.98
155_L	163_N	1.247	0.98
573_D	670_E	1.247	0.98
700_T	704_F	1.246	0.98
593_V	621_V	1.243	0.98
229_V	389_V	1.242	0.98
227_L	435_I	1.236	0.98
664_I	708_L	1.231	0.98
752_Y	759_G	1.231	0.98
157_R	325_E	1.228	0.98
571_H	576_H	1.228	0.98
13_A	20_T	1.222	0.98
674_E	698_G	1.218	0.98
316_L	322_H	1.216	0.98
391_F	427_W	1.212	0.98
715_I	731_L	1.212	0.98
102_P	130_S	1.209	0.98
662_S	686_A	1.197	0.97
700_T	733_L	1.196	0.97
416_L	420_W	1.193	0.97
572_A	647_K	1.191	0.97
674_E	733_L	1.190	0.97
624_G	636_V	1.189	0.97
141_N	719_K	1.188	0.97
129_M	171_N	1.184	0.97
502_D	555_F	1.184	0.97
79_Q	132_E	1.178	0.97
132_E	170_Q	1.178	0.97
334_V	366_S	1.178	0.97
742_L	747_N	1.178	0.97
238_L	393_T	1.177	0.97
244_T	289_S	1.176	0.97
54_S	61_L	1.175	0.97
204_I	425_I	1.174	0.97
665_L	690_K	1.167	0.97
53_F	58_F	1.160	0.97
666_T	669_L	1.159	0.97
159_H	319_N	1.155	0.97
330_L	370_L	1.153	0.97
13_A	21_A	1.152	0.97
51_C	56_I	1.152	0.97
403_G	414_G	1.152	0.97
222_T	226_K	1.150	0.97
213_R	238_L	1.150	0.97
190_I	206_Q	1.144	0.97
568_I	652_L	1.139	0.96
37_I	41_K	1.132	0.96
747_N	750_I	1.130	0.96
223_A	433_T	1.129	0.96
548_G	582_I	1.128	0.96
18_G	22_A	1.126	0.96
703_E	706_Q	1.124	0.96
622_K	625_D	1.121	0.96
510_D	525_I	1.119	0.96
217_E	220_V	1.119	0.96
701_G	733_L	1.117	0.96
53_F	62_Y	1.116	0.96
553_I	582_I	1.107	0.96
524_L	552_L	1.104	0.96
732_Q	735_Q	1.103	0.96
688_V	752_Y	1.101	0.96
270_P	290_G	1.100	0.96
137_L	164_Y	1.098	0.96
504_I	552_L	1.095	0.96
11_A	19_I	1.091	0.95
257_T	260_K	1.090	0.95
278_A	286_A	1.089	0.95
730_V	733_L	1.087	0.95
337_S	362_A	1.087	0.95
705_I	734_L	1.083	0.95
11_A	15_A	1.081	0.95
511_S	524_L	1.080	0.95
238_L	241_G	1.077	0.95
469_K	473_S	1.077	0.95
526_D	576_H	1.076	0.95
21_A	25_F	1.074	0.95
575_D	693_H	1.073	0.95
661_M	754_Y	1.073	0.95
12_A	16_T	1.072	0.95
213_R	239_H	1.071	0.95
49_I	59_F	1.068	0.95
611_A	618_I	1.068	0.95
646_S	650_S	1.066	0.95
272_Y	277_G	1.066	0.95
698_G	701_G	1.064	0.95
233_L	392_Y	1.063	0.95
375_H	558_A	1.060	0.95
685_K	709_Q	1.060	0.95
732_Q	736_R	1.059	0.95
126_E	129_M	1.057	0.95
49_I	53_F	1.057	0.95
234_A	279_A	1.053	0.95
514_V	525_I	1.052	0.94
568_I	593_V	1.050	0.94
24_Y	27_A	1.048	0.94
115_S	164_Y	1.046	0.94
597_G	650_S	1.045	0.94
190_I	210_V	1.042	0.94
84_I	125_I	1.040	0.94
671_K	675_Q	1.038	0.94
696_S	699_S	1.033	0.94
144_T	719_K	1.029	0.94
498_E	753_R	1.028	0.94
151_Y	154_Y	1.026	0.94
656_M	665_L	1.023	0.94
668_D	693_H	1.022	0.94
375_H	447_H	1.022	0.94
212_D	215_Y	1.022	0.94
11_A	17_A	1.014	0.93
547_L	551_V	1.013	0.93
524_L	583_L	1.013	0.93
265_L	269_L	1.009	0.93
99_V	133_L	1.008	0.93
674_E	701_G	1.007	0.93
411_A	414_G	1.006	0.93
548_G	579_E	1.004	0.93
349_K	353_G	1.003	0.93
527_T	583_L	1.002	0.93
307_A	311_S	1.000	0.93
46_F	53_F	0.997	0.93
57_L	62_Y	0.997	0.93
546_S	549_E	0.992	0.93
111_Y	118_E	0.992	0.93
16_T	20_T	0.992	0.93
518_H	630_K	0.990	0.92
731_L	745_D	0.989	0.92
12_A	20_T	0.987	0.92
288_M	311_S	0.986	0.92
663_W	752_Y	0.984	0.92
526_D	571_H	0.978	0.92
12_A	21_A	0.977	0.92
226_K	436_A	0.974	0.92
59_F	63_A	0.972	0.92
632_L	658_T	0.972	0.92
11_A	16_T	0.972	0.92
358_V	362_A	0.970	0.92
625_D	636_V	0.970	0.92
113_I	162_W	0.961	0.91
470_R	474_Q	0.960	0.91
575_D	648_N	0.958	0.91
85_D	100_E	0.956	0.91
594_I	618_I	0.953	0.91
482_C	485_V	0.952	0.91
205_V	421_F	0.948	0.91
548_G	553_I	0.948	0.91
523_V	629_I	0.948	0.91
15_A	19_I	0.945	0.91
244_T	265_L	0.943	0.91
522_R	565_D	0.942	0.90
224_Y	233_L	0.941	0.90
718_G	743_R	0.938	0.90
142_H	152_N	0.937	0.90
189_I	404_V	0.936	0.90
702_E	733_L	0.934	0.90
406_L	417_F	0.933	0.90
575_D	694_H	0.931	0.90
385_N	390_P	0.930	0.90
664_I	704_F	0.929	0.90
370_L	374_F	0.924	0.90
249_Y	253_R	0.923	0.90
668_D	694_H	0.922	0.90
700_T	715_I	0.920	0.89
391_F	424_L	0.919	0.89
98_M	160_I	0.917	0.89
355_L	386_M	0.917	0.89
14_S	18_G	0.912	0.89
731_L	743_R	0.912	0.89
221_L	225_Q	0.910	0.89
335_S	339_I	0.910	0.89
194_N	202_T	0.908	0.89
294_A	298_V	0.908	0.89
56_I	65_T	0.904	0.89
755_K	758_V	0.902	0.88
576_H	668_D	0.902	0.88
311_S	327_G	0.901	0.88
77_T	136_T	0.901	0.88
188_H	192_F	0.901	0.88
503_M	716_S	0.898	0.88
269_L	286_A	0.897	0.88
282_V	286_A	0.897	0.88
53_F	60_V	0.893	0.88
104_K	107_W	0.892	0.88
397_L	400_A	0.891	0.88
127_P	187_K	0.891	0.88
508_Q	726_P	0.890	0.88
522_R	561_I	0.889	0.88
416_L	419_S	0.888	0.88
13_A	17_A	0.885	0.88
54_S	65_T	0.885	0.88
144_T	148_A	0.884	0.87
280_P	362_A	0.884	0.87
621_V	625_D	0.884	0.87
647_K	650_S	0.883	0.87
55_F	58_F	0.883	0.87
56_I	61_L	0.883	0.87
303_R	306_T	0.883	0.87
515_G	561_I	0.881	0.87
508_Q	723_Y	0.879	0.87
710_P	737_H	0.878	0.87
51_C	58_F	0.877	0.87
362_A	366_S	0.876	0.87
516_A	632_L	0.876	0.87
499_G	514_V	0.875	0.87
666_T	690_K	0.873	0.87
500_E	559_K	0.872	0.87
734_L	739_I	0.871	0.87
549_E	582_I	0.870	0.87
30_L	39_L	0.866	0.86
501_V	665_L	0.866	0.86
712_T	740_R	0.863	0.86
309_C	313_I	0.862	0.86
571_H	575_D	0.859	0.86
717_A	725_H	0.858	0.86
295_G	302_V	0.858	0.86
206_Q	215_Y	0.857	0.86
430_R	434_N	0.856	0.86
654_L	665_L	0.855	0.86
192_F	407_L	0.850	0.85
222_T	225_Q	0.850	0.85
699_S	730_V	0.849	0.85
423_L	427_W	0.848	0.85
527_T	579_E	0.848	0.85
436_A	439_D	0.847	0.85
270_P	286_A	0.846	0.85
717_A	727_H	0.845	0.85
518_H	521_G	0.844	0.85
13_A	22_A	0.843	0.85
251_M	261_A	0.843	0.85
80_F	164_Y	0.842	0.85
335_S	362_A	0.841	0.85
235_I	282_V	0.840	0.85
545_F	548_G	0.840	0.85
512_M	570_T	0.840	0.85
648_N	693_H	0.839	0.85
208_L	398_P	0.836	0.84
469_K	475_L	0.836	0.84
146_P	751_Q	0.835	0.84
201_S	426_S	0.835	0.84
252_I	261_A	0.834	0.84
658_T	663_W	0.833	0.84
115_S	118_E	0.832	0.84
221_L	230_V	0.829	0.84
375_H	446_A	0.829	0.84
669_L	677_V	0.829	0.84
20_T	24_Y	0.829	0.84
251_M	264_L	0.826	0.84
419_S	423_L	0.825	0.84
235_I	398_P	0.825	0.84
471_S	475_L	0.825	0.84
223_A	432_I	0.824	0.84
143_A	148_A	0.822	0.83
153_E	157_R	0.820	0.83
661_M	687_D	0.820	0.83
144_T	505_D	0.818	0.83
155_L	328_F	0.817	0.83
14_S	17_A	0.816	0.83
666_T	704_F	0.816	0.83
503_M	744_T	0.815	0.83
404_V	408_S	0.815	0.83
266_L	270_P	0.815	0.83
575_D	668_D	0.815	0.83
53_F	61_L	0.814	0.83
376_Q	442_T	0.814	0.83
701_G	704_F	0.813	0.83
686_A	704_F	0.812	0.83
503_M	750_I	0.812	0.83
674_E	705_I	0.809	0.82
53_F	59_F	0.806	0.82
703_E	707_Q	0.806	0.82
512_M	524_L	0.806	0.82
665_L	692_G	0.806	0.82
366_S	370_L	0.804	0.82
380_I	438_V	0.803	0.82
336_F	340_L	0.802	0.82
666_T	689_L	0.802	0.82
682_P	686_A	0.801	0.82
63_A	66_D	0.801	0.82
56_I	60_V	0.800	0.82
668_D	695_G	0.800	0.82
702_E	736_R	0.798	0.82
15_A	20_T	0.798	0.82
392_Y	428_I	0.797	0.81
113_I	117_G	0.796	0.81
13_A	18_G	0.795	0.81
104_K	110_A	0.793	0.81
514_V	634_F	0.792	0.81
49_I	56_I	0.790	0.81
13_A	19_I	0.789	0.81
19_I	33_L	0.789	0.81
85_D	112_R	0.788	0.81
648_N	651_S	0.788	0.81
12_A	18_G	0.787	0.81
247_L	251_M	0.787	0.81
525_I	690_K	0.787	0.81
689_L	739_I	0.786	0.81
638_S	673_G	0.786	0.81
508_Q	717_A	0.786	0.81
11_A	20_T	0.785	0.80
269_L	652_L	0.785	0.80
111_Y	115_S	0.783	0.80
239_H	279_A	0.783	0.80
210_V	404_V	0.782	0.80
406_L	410_S	0.782	0.80
232_L	392_Y	0.781	0.80
151_Y	163_N	0.781	0.80
731_L	735_Q	0.781	0.80
674_E	692_G	0.781	0.80
278_A	283_L	0.780	0.80
243_L	247_L	0.778	0.80
508_Q	575_D	0.778	0.80
204_I	229_V	0.777	0.80
593_V	636_V	0.776	0.80
14_S	24_Y	0.776	0.80
658_T	661_M	0.776	0.80
527_T	548_G	0.774	0.80
14_S	19_I	0.774	0.80
576_H	693_H	0.773	0.79
58_F	62_Y	0.770	0.79
510_D	665_L	0.770	0.79
51_C	59_F	0.770	0.79
527_T	552_L	0.770	0.79
666_T	691_V	0.769	0.79
581_E	585_K	0.768	0.79
744_T	750_I	0.768	0.79
571_H	693_H	0.767	0.79
563_Q	588_K	0.767	0.79
208_L	235_I	0.766	0.79
231_H	385_N	0.765	0.79
743_R	747_N	0.765	0.79
431_L	434_N	0.764	0.79
510_D	716_S	0.764	0.79
394_F	398_P	0.763	0.79
58_F	61_L	0.762	0.78
571_H	668_D	0.761	0.78
548_G	552_L	0.761	0.78
204_I	207_A	0.760	0.78
87_I	277_G	0.760	0.78
741_V	745_D	0.760	0.78
655_W	681_F	0.759	0.78
36_L	40_I	0.757	0.78
41_K	416_L	0.757	0.78
499_G	659_G	0.756	0.78
484_T	487_F	0.755	0.78
503_M	510_D	0.755	0.78
692_G	699_S	0.753	0.78
18_G	27_A	0.752	0.78
471_S	474_Q	0.751	0.77
11_A	18_G	0.751	0.77
47_L	59_F	0.751	0.77
727_H	731_L	0.750	0.77
499_G	632_L	0.749	0.77
60_V	65_T	0.747	0.77
545_F	550_K	0.745	0.77
714_I	744_T	0.744	0.77
556_L	561_I	0.744	0.77
656_M	663_W	0.744	0.77
529_G	578_G	0.744	0.77
658_T	754_Y	0.743	0.77
50_V	53_F	0.743	0.77
380_I	439_D	0.743	0.77
584_L	611_A	0.743	0.77
718_G	745_D	0.742	0.77
516_A	634_F	0.741	0.77
392_Y	396_I	0.741	0.77
229_V	289_S	0.740	0.76
62_Y	66_D	0.739	0.76
521_G	629_I	0.738	0.76
718_G	726_P	0.738	0.76
653_V	666_T	0.737	0.76
14_S	25_F	0.736	0.76
610_A	614_E	0.736	0.76
430_R	433_T	0.735	0.76
243_L	275_L	0.734	0.76
688_V	714_I	0.733	0.76
575_D	695_G	0.733	0.76
385_N	389_V	0.732	0.76
185_L	271_L	0.731	0.76
334_V	362_A	0.729	0.75
690_K	715_I	0.727	0.75
622_K	641_A	0.726	0.75
12_A	17_A	0.726	0.75
648_N	668_D	0.726	0.75
170_Q	173_S	0.725	0.75
227_L	432_I	0.725	0.75
506_I	509_G	0.725	0.75
314_V	317_L	0.724	0.75
691_V	717_A	0.721	0.75
678_M	704_F	0.720	0.74
559_K	751_Q	0.720	0.74
576_H	694_H	0.719	0.74
508_Q	724_H	0.719	0.74
646_S	649_N	0.719	0.74
573_D	723_Y	0.717	0.74
133_L	164_Y	0.716	0.74
49_I	52_F	0.715	0.74
141_N	144_T	0.714	0.74
205_V	209_T	0.714	0.74
185_L	188_H	0.713	0.74
42_T	45_A	0.712	0.74
512_M	750_I	0.712	0.74
17_A	23_A	0.711	0.74
408_S	414_G	0.711	0.74
638_S	669_L	0.710	0.73
453_L	456_F	0.709	0.73
210_V	276_T	0.709	0.73
692_G	723_Y	0.708	0.73
648_N	694_H	0.708	0.73
623_R	639_P	0.708	0.73
48_I	61_L	0.707	0.73
152_N	156_Y	0.707	0.73
18_G	23_A	0.707	0.73
280_P	322_H	0.706	0.73
472_L	475_L	0.705	0.73
372_Y	447_H	0.705	0.73
182_V	274_M	0.705	0.73
202_T	215_Y	0.705	0.73
504_I	548_G	0.705	0.73
673_G	692_G	0.704	0.73
133_L	166_V	0.704	0.73
59_F	66_D	0.704	0.73
387_L	431_L	0.704	0.73
54_S	60_V	0.704	0.73
669_L	734_L	0.703	0.73
689_L	700_T	0.703	0.73
570_T	667_G	0.703	0.73
12_A	19_I	0.701	0.72
591_R	617_A	0.700	0.72
566_A	627_L	0.699	0.72
235_I	573_D	0.698	0.72
358_V	389_V	0.698	0.72
607_V	611_A	0.698	0.72
276_T	282_V	0.697	0.72
80_F	113_I	0.696	0.72
54_S	66_D	0.696	0.72
238_L	389_V	0.695	0.72
73_Y	78_Y	0.694	0.72
678_M	703_E	0.693	0.72
570_T	654_L	0.693	0.72
155_L	160_I	0.692	0.72
685_K	711_K	0.692	0.72
60_V	63_A	0.692	0.72
721_N	725_H	0.691	0.71
17_A	22_A	0.691	0.71
523_V	634_F	0.689	0.71
469_K	472_L	0.689	0.71
234_A	308_I	0.688	0.71
103_D	107_W	0.688	0.71
158_Q	325_E	0.688	0.71
314_V	318_F	0.687	0.71
182_V	271_L	0.687	0.71
592_L	618_I	0.687	0.71
273_V	283_L	0.686	0.71
583_L	589_V	0.686	0.71
653_V	677_V	0.686	0.71
501_V	512_M	0.684	0.71
235_I	389_V	0.683	0.71
511_S	578_G	0.683	0.71
668_D	696_S	0.683	0.71
13_A	25_F	0.681	0.70
82_A	131_C	0.680	0.70
302_V	307_A	0.680	0.70
22_A	25_F	0.680	0.70
41_K	45_A	0.679	0.70
29_F	32_I	0.679	0.70
569_L	592_L	0.678	0.70
623_R	680_V	0.676	0.70
635_H	662_S	0.676	0.70
46_F	58_F	0.676	0.70
580_A	583_L	0.675	0.70
553_I	557_T	0.674	0.70
193_T	209_T	0.674	0.70
691_V	739_I	0.673	0.69
730_V	734_L	0.673	0.69
263_I	297_L	0.671	0.69
57_L	61_L	0.670	0.69
521_G	631_D	0.670	0.69
142_H	148_A	0.670	0.69
480_G	484_T	0.669	0.69
235_I	281_S	0.668	0.69
61_L	66_D	0.668	0.69
329_Q	652_L	0.668	0.69
282_V	285_A	0.667	0.69
401_V	417_F	0.666	0.69
474_Q	479_G	0.665	0.68
280_P	283_L	0.665	0.68
549_E	554_P	0.665	0.68
19_I	25_F	0.665	0.68
306_T	310_L	0.664	0.68
628_Q	631_D	0.663	0.68
248_F	261_A	0.663	0.68
291_V	307_A	0.663	0.68
570_T	698_G	0.663	0.68
212_D	331_S	0.663	0.68
206_Q	212_D	0.663	0.68
677_V	704_F	0.661	0.68
754_Y	757_R	0.660	0.68
624_G	637_L	0.660	0.68
671_K	698_G	0.658	0.68
24_Y	28_I	0.657	0.68
62_Y	65_T	0.657	0.68
327_G	654_L	0.655	0.67
52_F	406_L	0.654	0.67
476_M	479_G	0.653	0.67
712_T	739_I	0.652	0.67
564_L	589_V	0.652	0.67
216_V	221_L	0.652	0.67
692_G	701_G	0.652	0.67
240_V	627_L	0.651	0.67
754_Y	759_G	0.651	0.67
49_I	63_A	0.650	0.67
693_H	696_S	0.650	0.67
80_F	486_M	0.650	0.67
224_Y	229_V	0.650	0.67
675_Q	701_G	0.648	0.66
545_F	595_P	0.648	0.66
229_V	388_M	0.648	0.66
524_L	582_I	0.647	0.66
694_H	718_G	0.646	0.66
53_F	65_T	0.645	0.66
292_Y	296_S	0.644	0.66
566_A	634_F	0.642	0.66
252_I	258_R	0.642	0.66
241_G	244_T	0.641	0.66
88_P	97_M	0.640	0.66
435_I	438_V	0.640	0.66
567_L	589_V	0.640	0.66
227_L	384_M	0.639	0.65
695_G	718_G	0.639	0.65
526_D	668_D	0.638	0.65
692_G	715_I	0.638	0.65
657_E	660_G	0.638	0.65
668_D	726_P	0.638	0.65
689_L	704_F	0.638	0.65
189_I	210_V	0.638	0.65
572_A	577_I	0.637	0.65
117_G	166_V	0.637	0.65
718_G	724_H	0.636	0.65
262_S	297_L	0.636	0.65
16_T	24_Y	0.635	0.65
56_I	62_Y	0.635	0.65
655_W	707_Q	0.634	0.65
193_T	210_V	0.633	0.65
91_D	94_R	0.633	0.65
718_G	725_H	0.632	0.65
17_A	24_Y	0.631	0.64
525_I	667_G	0.631	0.64
576_H	695_G	0.631	0.64
58_F	63_A	0.631	0.64
150_D	153_E	0.631	0.64
16_T	19_I	0.630	0.64
570_T	653_V	0.630	0.64
207_A	349_K	0.629	0.64
571_H	694_H	0.629	0.64
505_D	573_D	0.629	0.64
693_H	726_P	0.628	0.64
275_L	428_I	0.627	0.64
527_T	582_I	0.627	0.64
187_K	191_S	0.627	0.64
449_A	452_L	0.625	0.64
280_P	338_L	0.625	0.64
311_S	315_L	0.624	0.64
84_I	97_M	0.623	0.63
389_V	393_T	0.623	0.63
502_D	559_K	0.622	0.63
506_I	576_H	0.621	0.63
131_C	583_L	0.621	0.63
49_I	57_L	0.621	0.63
18_G	31_F	0.620	0.63
279_A	393_T	0.619	0.63
70_V	73_Y	0.619	0.63
197_L	403_G	0.618	0.63
243_L	268_F	0.618	0.63
516_A	521_G	0.616	0.63
353_G	357_I	0.616	0.63
380_I	441_F	0.614	0.62
706_Q	735_Q	0.614	0.62
234_A	241_G	0.614	0.62
310_L	552_L	0.614	0.62
673_G	676_E	0.613	0.62
718_G	723_Y	0.612	0.62
404_V	407_L	0.611	0.62
653_V	664_I	0.610	0.62
235_I	276_T	0.610	0.62
609_Q	612_R	0.610	0.62
422_D	426_S	0.610	0.62
694_H	726_P	0.610	0.62
510_D	666_T	0.609	0.62
308_I	336_F	0.609	0.62
693_H	718_G	0.609	0.62
456_F	460_I	0.608	0.62
280_P	315_L	0.608	0.62
668_D	718_G	0.608	0.62
178_F	181_K	0.608	0.62
695_G	726_P	0.606	0.61
285_A	338_L	0.605	0.61
54_S	62_Y	0.605	0.61
82_A	97_M	0.605	0.61
146_P	502_D	0.604	0.61
223_A	436_A	0.604	0.61
479_G	483_C	0.603	0.61
550_K	572_A	0.603	0.61
383_P	714_I	0.603	0.61
208_L	232_L	0.602	0.61
527_T	569_L	0.601	0.61
678_M	681_F	0.600	0.61
41_K	44_H	0.600	0.61
397_L	401_V	0.600	0.61
499_G	663_W	0.600	0.61
621_V	624_G	0.599	0.60
334_V	361_I	0.598	0.60
501_V	514_V	0.598	0.60
690_K	721_N	0.598	0.60
359_S	652_L	0.598	0.60
526_D	694_H	0.597	0.60
487_F	490_F	0.596	0.60
140_P	151_Y	0.593	0.60
269_L	289_S	0.593	0.60
360_L	483_C	0.593	0.60
637_L	655_W	0.593	0.60
225_Q	230_V	0.592	0.60
203_G	220_V	0.591	0.59
234_A	334_V	0.591	0.59
276_T	355_L	0.590	0.59
621_V	636_V	0.590	0.59
14_S	22_A	0.590	0.59
338_L	686_A	0.590	0.59
338_L	342_S	0.590	0.59
366_S	381_S	0.589	0.59
315_L	517_P	0.589	0.59
670_E	698_G	0.588	0.59
398_P	402_A	0.588	0.59
696_S	726_P	0.586	0.59
18_G	25_F	0.586	0.59
669_L	699_S	0.585	0.59
281_S	285_A	0.585	0.59
567_L	570_T	0.584	0.59
206_Q	210_V	0.584	0.59
86_T	98_M	0.584	0.59
190_I	194_N	0.584	0.59
276_T	398_P	0.583	0.58
313_I	428_I	0.583	0.58
280_P	327_G	0.580	0.58
312_Y	316_L	0.580	0.58
326_A	374_F	0.579	0.58
526_D	693_H	0.578	0.58
356_T	360_L	0.578	0.58
220_V	224_Y	0.578	0.58
671_K	700_T	0.578	0.58
526_D	575_D	0.577	0.58
663_W	754_Y	0.577	0.58
367_L	371_L	0.574	0.57
285_A	293_L	0.574	0.57
329_Q	359_S	0.574	0.57
482_C	712_T	0.574	0.57
546_S	579_E	0.573	0.57
55_F	61_L	0.573	0.57
637_L	641_A	0.572	0.57
77_T	81_K	0.572	0.57
509_G	576_H	0.572	0.57
495_L	498_E	0.572	0.57
202_T	206_Q	0.571	0.57
425_I	666_T	0.571	0.57
21_A	26_P	0.571	0.57
280_P	325_E	0.571	0.57
573_D	576_H	0.570	0.57
38_I	42_T	0.568	0.56
273_V	281_S	0.567	0.56
318_F	704_F	0.567	0.56
676_E	680_V	0.565	0.56
644_P	650_S	0.565	0.56
728_Q	731_L	0.564	0.56
147_G	555_F	0.563	0.56
138_E	165_S	0.563	0.56
207_A	276_T	0.562	0.56
171_N	174_E	0.562	0.56
204_I	224_Y	0.561	0.56
46_F	60_V	0.561	0.56
386_M	461_I	0.560	0.55
150_D	229_V	0.560	0.55
705_I	731_L	0.560	0.55
12_A	23_A	0.560	0.55
459_T	463_L	0.559	0.55
227_L	334_V	0.559	0.55
348_V	352_L	0.558	0.55
529_G	573_D	0.558	0.55
31_F	35_L	0.558	0.55
338_L	709_Q	0.558	0.55
59_F	67_S	0.557	0.55
139_E	152_N	0.557	0.55
661_M	759_G	0.557	0.55
315_L	328_F	0.557	0.55
29_F	36_L	0.556	0.55
450_P	453_L	0.556	0.55
241_G	285_A	0.556	0.55
234_A	239_H	0.556	0.55
25_F	29_F	0.555	0.55
499_G	755_K	0.555	0.55
115_S	291_V	0.555	0.55
706_Q	739_I	0.554	0.55
558_A	749_T	0.553	0.54
35_L	477_V	0.553	0.54
213_R	225_Q	0.553	0.54
276_T	279_A	0.553	0.54
509_G	526_D	0.553	0.54
68_Q	73_Y	0.553	0.54
645_A	649_N	0.552	0.54
230_V	374_F	0.552	0.54
241_G	553_I	0.552	0.54
507_G	668_D	0.551	0.54
31_F	39_L	0.550	0.54
399_G	421_F	0.550	0.54
557_T	586_H	0.549	0.54
314_V	340_L	0.549	0.54
576_H	726_P	0.549	0.54
24_Y	38_I	0.549	0.54
77_T	134_T	0.547	0.54
125_I	129_M	0.546	0.54
55_F	59_F	0.546	0.54
36_L	483_C	0.546	0.54
477_V	750_I	0.545	0.53
526_D	695_G	0.545	0.53
443_I	569_L	0.544	0.53
700_T	739_I	0.544	0.53
45_A	48_I	0.543	0.53
314_V	399_G	0.543	0.53
691_V	700_T	0.542	0.53
232_L	398_P	0.542	0.53
351_S	354_Q	0.541	0.53
665_L	670_E	0.541	0.53
508_Q	576_H	0.541	0.53
213_R	230_V	0.541	0.53
143_A	551_V	0.541	0.53
499_G	660_G	0.539	0.53
354_Q	688_V	0.539	0.53
83_V	100_E	0.539	0.53
343_S	361_I	0.539	0.53
473_S	481_I	0.538	0.52
329_Q	333_A	0.538	0.52
607_V	610_A	0.538	0.52
426_S	430_R	0.537	0.52
508_Q	668_D	0.537	0.52
11_A	27_A	0.537	0.52
192_F	196_L	0.537	0.52
527_T	581_E	0.537	0.52
510_D	570_T	0.536	0.52
48_I	51_C	0.536	0.52
73_Y	137_L	0.536	0.52
220_V	223_A	0.536	0.52
80_F	85_D	0.536	0.52
16_T	32_I	0.536	0.52
272_Y	289_S	0.535	0.52
453_L	457_T	0.535	0.52
508_Q	529_G	0.535	0.52
649_N	669_L	0.534	0.52
137_L	140_P	0.533	0.52
194_N	215_Y	0.533	0.52
261_A	265_L	0.533	0.52
729_K	733_L	0.532	0.52
465_M	514_V	0.532	0.52
575_D	718_G	0.532	0.52
545_F	549_E	0.532	0.52
15_A	21_A	0.532	0.52
415_R	750_I	0.532	0.52
50_V	54_S	0.532	0.52
575_D	726_P	0.531	0.52
319_N	322_H	0.530	0.51
648_N	695_G	0.530	0.51
481_I	484_T	0.529	0.51
391_F	396_I	0.529	0.51
296_S	300_W	0.528	0.51
38_I	41_K	0.528	0.51
150_D	240_V	0.527	0.51
570_T	666_T	0.527	0.51
158_Q	285_A	0.527	0.51
374_F	554_P	0.527	0.51
288_M	327_G	0.527	0.51
337_S	361_I	0.527	0.51
47_L	51_C	0.527	0.51
225_Q	381_S	0.525	0.51
356_T	386_M	0.525	0.51
624_G	638_S	0.525	0.51
23_A	28_I	0.524	0.51
508_Q	573_D	0.524	0.51
713_A	737_H	0.523	0.50
56_I	59_F	0.523	0.50
571_H	695_G	0.523	0.50
269_L	366_S	0.523	0.50
465_M	583_L	0.522	0.50
525_I	654_L	0.522	0.50
96_S	114_Q	0.522	0.50
725_H	743_R	0.522	0.50
12_A	35_L	0.522	0.50
388_M	392_Y	0.522	0.50
700_T	737_H	0.522	0.50
640_E	676_E	0.521	0.50
37_I	40_I	0.521	0.50
388_M	428_I	0.521	0.50
659_G	756_N	0.520	0.50
270_P	278_A	0.519	0.50
18_G	24_Y	0.518	0.50
12_A	32_I	0.518	0.50
481_I	633_Q	0.518	0.50
53_F	66_D	0.518	0.50
115_S	166_V	0.518	0.50
244_T	269_L	0.518	0.50
549_E	586_H	0.517	0.50
573_D	668_D	0.517	0.50
232_L	338_L	0.517	0.50
96_S	99_V	0.516	0.50
532_S	551_V	0.516	0.50
661_M	752_Y	0.516	0.50
12_A	22_A	0.516	0.50
21_A	24_Y	0.516	0.50
23_A	40_I	0.516	0.50
392_Y	397_L	0.515	0.49
657_E	735_Q	0.515	0.49
230_V	339_I	0.514	0.49
15_A	22_A	0.514	0.49
485_V	488_L	0.514	0.49
209_T	397_L	0.513	0.49
614_E	617_A	0.513	0.49
281_S	331_S	0.513	0.49
58_F	64_V	0.512	0.49
132_E	172_C	0.512	0.49
86_T	89_K	0.512	0.49
203_G	564_L	0.510	0.49
234_A	698_G	0.509	0.49
306_T	309_C	0.509	0.49
54_S	59_F	0.509	0.49
267_L	290_G	0.509	0.49
579_E	582_I	0.509	0.49
19_I	24_Y	0.509	0.49
359_S	621_V	0.508	0.48
687_D	690_K	0.508	0.48
225_Q	240_V	0.508	0.48
184_S	552_L	0.508	0.48
213_R	279_A	0.508	0.48
210_V	275_L	0.507	0.48
239_H	272_Y	0.507	0.48
12_A	24_Y	0.507	0.48
660_G	711_K	0.507	0.48
379_I	383_P	0.504	0.48
54_S	64_V	0.504	0.48
517_P	658_T	0.504	0.48
648_N	696_S	0.503	0.48
25_F	32_I	0.503	0.48
22_A	29_F	0.502	0.48
683_N	686_A	0.502	0.48
57_L	63_A	0.502	0.48
459_T	482_C	0.502	0.48
47_L	60_V	0.501	0.48
580_A	584_L	0.501	0.48
713_A	741_V	0.501	0.48
445_I	455_L	0.501	0.48
594_I	620_E	0.500	0.47
57_L	421_F	0.500	0.47
22_A	454_F	0.500	0.47

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2bibA	1	0.3608	100	0.742	Contact Map
3bv6A	5	0.3853	100	0.809	Contact Map
2wylA	5	0.3441	100	0.814	Contact Map
2gcuA	3	0.2758	100	0.823	Contact Map
3adrA	1	0.2784	100	0.826	Contact Map
4ysbA	2	0.2603	100	0.836	Contact Map
4chlA	2	0.2539	100	0.841	Contact Map
2qedA	1	0.2784	100	0.845	Contact Map
3jxpA	2	0.3015	100	0.858	Contact Map
1qh5A	1	0.2809	100	0.858	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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