ROCC - BACSU - GREMLIN Contacts

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ROCC - Amino-acid permease RocC

UniProt:	P39636	Sequences: MQNHKNELQRSMKSRHLFMIALGGVIGTGLFLGSGFTISQAGPLGAIAAYIIGGFLMYLVMLCLGELAVAMPVAGSFQAYATKFLGQSTGFMIGWLYWFSWANTVGLELTSAGILMQRWLPSVPIWIWCLVFGIVIFLINALSVRSFAEMEFWFSSIKVAAIILFIVIGGAAVFGLIDFKGGQETPFLSNFMTDRGLFPNGVLAVMFTLVMVNFSFQGTELVGIAAGESESPEKTLPKSIRNVIWRTLFFFVLAMFVLVAILPYKTAGVIESPFVAVLDQIGIPFSADIMNFVILTAILSVANSGLYAASRMMWSLSSNQMGPSFLTRLTKKGVPMNALLITLGISGCSLLTSVMAAETVYLWCISISGMVTVVAWMSICASQFFFRRRFLAEGGNVNDLEFRTPLYPLVPILGFCLYGCVLISLIFIPDQRIGLYCGVPIIIFCYAYYHLSIKKRINHETIEKKQTEAQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	470 (424)
Sequences:	24717 (16067)
Seq/√Len:	780.3

ECOLI - YIFK MMUP AROP LYSP GABP PROY ANSP CYCA PHEP PUUP FRLA PLAP GADC POTE YGJI YCAM ADIC YJEM ARCD YBAT CADB YJEH TNAB
BACSU - ROCC YBGF HUTM GABP ROCE YTNA YBXG AAPA YVBW YDGF YBEC ASPP STET YCGH YHDG YFNA ARCD YECA YDAO GERBB GERAB YNDE GERKB
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97WS3 Q97X49 Q97U05 Q97ZB5 Q97Z63 Q7LXI7 Q97XM0 Q97VA6 Q97U33 Q97WD4 Q97VA8 Q97VR4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
137_F	343_L	4.468	1.00
325_F	337_N	4.402	1.00
385_F	389_R	3.474	1.00
54_G	248_L	3.254	1.00
377_M	415_F	3.212	1.00
328_R	337_N	3.129	1.00
234_K	238_K	3.023	1.00
13_K	230_E	2.910	1.00
231_S	234_K	2.787	1.00
78_Q	319_N	2.733	1.00
229_S	235_T	2.706	1.00
18_F	242_N	2.630	1.00
94_G	316_L	2.624	1.00
169_G	257_V	2.597	1.00
317_S	327_T	2.595	1.00
330_T	336_M	2.547	1.00
130_L	347_G	2.546	1.00
325_F	328_R	2.524	1.00
285_F	289_I	2.419	1.00
14_S	242_N	2.396	1.00
167_V	171_A	2.336	1.00
227_G	318_S	2.322	1.00
82_T	90_G	2.241	1.00
66_E	387_R	2.193	1.00
228_E	311_R	2.178	1.00
138_L	142_L	2.176	1.00
340_L	344_G	2.171	1.00
314_W	318_S	2.158	1.00
436_Y	440_P	2.131	1.00
134_I	347_G	2.127	1.00
380_C	414_G	2.122	1.00
14_S	235_T	2.093	1.00
17_L	229_S	2.088	1.00
137_F	339_L	2.081	1.00
145_R	149_E	2.062	1.00
412_I	416_C	2.049	1.00
276_A	279_D	2.042	1.00
14_S	18_F	2.026	1.00
238_K	242_N	2.026	1.00
141_A	336_M	2.006	1.00
129_C	350_L	2.005	1.00
18_F	246_R	2.005	1.00
187_F	190_N	2.004	1.00
82_T	87_Q	1.990	1.00
266_T	280_Q	1.970	1.00
156_S	160_A	1.966	1.00
85_L	385_F	1.957	1.00
130_L	350_L	1.953	1.00
37_T	46_A	1.941	1.00
13_K	16_H	1.927	1.00
326_L	341_I	1.925	1.00
440_P	443_I	1.924	1.00
63_C	380_C	1.923	1.00
446_Y	450_H	1.915	1.00
55_F	59_L	1.912	1.00
447_A	451_L	1.874	1.00
98_W	342_T	1.870	1.00
8_L	329_L	1.864	1.00
263_P	266_T	1.857	1.00
320_Q	324_S	1.857	1.00
85_L	381_A	1.847	1.00
276_A	280_Q	1.832	1.00
241_R	245_W	1.774	1.00
231_S	235_T	1.748	1.00
134_I	343_L	1.737	1.00
81_A	93_I	1.720	1.00
86_G	89_T	1.705	1.00
330_T	334_V	1.684	1.00
409_L	413_L	1.677	1.00
16_H	152_F	1.677	1.00
140_N	303_N	1.672	1.00
141_A	340_L	1.661	1.00
160_A	164_L	1.651	1.00
444_F	448_Y	1.645	1.00
93_I	378_S	1.644	1.00
385_F	388_R	1.612	1.00
332_K	336_M	1.609	1.00
21_A	243_V	1.603	1.00
105_V	346_S	1.580	1.00
440_P	444_F	1.578	1.00
49_A	208_T	1.565	1.00
12_M	16_H	1.563	1.00
279_D	287_A	1.559	1.00
245_W	249_F	1.553	1.00
188_L	191_F	1.543	1.00
109_L	302_A	1.537	1.00
85_L	89_T	1.533	1.00
445_C	448_Y	1.529	1.00
442_I	446_Y	1.514	1.00
133_G	346_S	1.513	1.00
9_Q	333_G	1.504	1.00
56_L	417_L	1.499	1.00
381_A	415_F	1.498	1.00
416_C	420_C	1.495	1.00
225_A	307_Y	1.480	1.00
142_L	332_K	1.475	1.00
381_A	385_F	1.474	1.00
116_M	128_W	1.466	1.00
53_G	212_V	1.465	1.00
59_L	413_L	1.458	1.00
443_I	447_A	1.457	1.00
313_M	338_A	1.452	1.00
170_G	257_V	1.447	1.00
309_A	342_T	1.443	1.00
130_L	134_I	1.437	1.00
337_N	341_I	1.435	1.00
231_S	238_K	1.434	1.00
314_W	329_L	1.431	1.00
432_R	435_L	1.413	1.00
133_G	343_L	1.412	1.00
61_M	244_I	1.408	1.00
324_S	327_T	1.406	1.00
161_A	293_V	1.404	1.00
431_Q	434_G	1.388	1.00
310_S	339_L	1.387	1.00
81_A	378_S	1.379	1.00
438_G	442_I	1.371	1.00
74_A	227_G	1.363	1.00
137_F	340_L	1.360	1.00
8_L	314_W	1.357	1.00
187_F	191_F	1.356	1.00
88_S	449_Y	1.354	1.00
324_S	328_R	1.351	1.00
16_H	148_A	1.350	1.00
434_G	438_G	1.339	1.00
407_Y	411_P	1.338	1.00
328_R	336_M	1.332	1.00
249_F	253_L	1.331	1.00
12_M	17_L	1.330	1.00
109_L	133_G	1.329	1.00
270_I	276_A	1.324	1.00
55_F	413_L	1.321	1.00
71_M	83_K	1.314	1.00
173_V	260_A	1.311	1.00
288_D	292_F	1.309	1.00
159_V	163_I	1.307	1.00
112_A	295_L	1.300	1.00
235_T	238_K	1.296	1.00
112_A	132_F	1.290	1.00
84_F	382_S	1.285	1.00
61_M	240_I	1.284	1.00
63_C	411_P	1.282	1.00
14_S	238_K	1.267	1.00
60_V	380_C	1.264	1.00
232_P	237_P	1.263	1.00
414_G	418_Y	1.257	1.00
15_R	19_M	1.252	1.00
47_I	256_F	1.250	1.00
136_I	302_A	1.240	1.00
166_I	253_L	1.239	1.00
441_I	445_C	1.238	1.00
279_D	284_P	1.228	1.00
126_W	130_L	1.225	1.00
272_S	276_A	1.223	1.00
62_L	241_R	1.221	1.00
426_I	429_P	1.218	1.00
408_P	412_I	1.215	1.00
73_V	79_A	1.215	1.00
25_V	247_T	1.208	1.00
430_D	434_G	1.208	1.00
108_E	301_V	1.201	1.00
430_D	433_I	1.201	1.00
391_L	400_L	1.195	1.00
124_P	127_I	1.183	1.00
79_A	83_K	1.180	1.00
44_L	205_V	1.178	1.00
186_P	189_S	1.176	1.00
420_C	424_S	1.170	1.00
431_Q	435_L	1.166	1.00
433_I	440_P	1.165	1.00
32_L	111_S	1.164	1.00
313_M	322_G	1.163	1.00
433_I	436_Y	1.162	1.00
86_G	90_G	1.162	1.00
165_F	169_G	1.160	1.00
12_M	148_A	1.154	1.00
430_D	444_F	1.154	1.00
21_A	222_V	1.136	1.00
122_S	125_I	1.128	1.00
201_G	204_A	1.124	1.00
169_G	261_I	1.119	1.00
398_N	401_E	1.118	1.00
230_E	235_T	1.115	1.00
406_L	410_V	1.114	1.00
170_G	174_F	1.112	1.00
151_E	303_N	1.107	1.00
446_Y	449_Y	1.106	1.00
64_L	77_F	1.105	1.00
164_L	168_I	1.104	1.00
17_L	239_S	1.104	1.00
397_V	400_L	1.102	1.00
20_I	225_A	1.102	1.00
139_I	150_M	1.100	1.00
406_L	409_L	1.098	1.00
186_P	190_N	1.094	1.00
150_M	154_F	1.092	1.00
127_I	131_V	1.090	1.00
383_Q	411_P	1.090	1.00
70_A	400_L	1.090	1.00
318_S	327_T	1.088	1.00
98_W	313_M	1.084	1.00
83_K	390_F	1.084	1.00
73_V	83_K	1.080	1.00
187_F	192_M	1.068	1.00
388_R	391_L	1.066	1.00
11_S	230_E	1.064	1.00
38_I	46_A	1.061	1.00
149_E	153_W	1.059	1.00
81_A	89_T	1.057	1.00
419_G	423_I	1.054	1.00
415_F	419_G	1.051	1.00
22_L	246_R	1.045	1.00
91_F	95_W	1.045	1.00
422_L	425_L	1.042	1.00
163_I	167_V	1.041	1.00
68_A	80_Y	1.038	1.00
409_L	412_I	1.036	1.00
337_N	340_L	1.035	1.00
131_V	135_V	1.032	1.00
445_C	449_Y	1.031	1.00
329_L	333_G	1.020	1.00
22_L	247_T	1.020	1.00
435_L	438_G	1.019	1.00
113_G	128_W	1.013	1.00
51_I	252_V	1.011	1.00
391_L	397_V	1.010	1.00
144_V	307_Y	1.009	1.00
78_Q	315_S	1.008	1.00
185_T	188_L	1.006	1.00
70_A	398_N	1.005	1.00
137_F	141_A	1.002	1.00
439_V	443_I	1.001	1.00
384_F	412_I	1.001	1.00
41_A	44_L	1.000	1.00
442_I	445_C	0.999	1.00
263_P	280_Q	0.994	1.00
444_F	450_H	0.994	1.00
154_F	300_S	0.992	1.00
66_E	69_V	0.987	1.00
116_M	120_L	0.985	1.00
141_A	334_V	0.982	1.00
123_V	127_I	0.980	1.00
380_C	415_F	0.974	1.00
390_F	397_V	0.973	1.00
432_R	436_Y	0.972	1.00
171_A	175_G	0.971	1.00
134_I	138_L	0.966	1.00
377_M	419_G	0.966	1.00
387_R	391_L	0.965	1.00
436_Y	443_I	0.958	1.00
444_F	451_L	0.955	1.00
344_G	348_C	0.952	1.00
206_M	420_C	0.950	1.00
388_R	408_P	0.950	1.00
282_G	286_S	0.947	1.00
284_P	288_D	0.942	1.00
159_V	250_F	0.941	1.00
135_V	299_L	0.921	1.00
248_L	252_V	0.920	1.00
217_Q	372_T	0.915	1.00
59_L	410_V	0.912	1.00
190_N	194_D	0.912	1.00
273_P	278_L	0.906	1.00
19_M	152_F	0.902	1.00
400_L	403_R	0.898	1.00
136_I	303_N	0.898	1.00
377_M	381_A	0.897	1.00
226_A	236_L	0.895	1.00
26_I	29_G	0.889	1.00
11_S	145_R	0.882	1.00
184_E	188_L	0.881	1.00
283_I	286_S	0.881	1.00
418_Y	421_V	0.878	1.00
411_P	414_G	0.877	1.00
166_I	170_G	0.875	1.00
69_V	401_E	0.875	1.00
436_Y	447_A	0.873	1.00
166_I	257_V	0.871	1.00
242_N	246_R	0.867	1.00
113_G	129_C	0.859	1.00
141_A	330_T	0.858	1.00
202_V	205_V	0.858	1.00
95_W	322_G	0.857	1.00
47_I	259_V	0.857	1.00
220_E	224_I	0.857	1.00
377_M	418_Y	0.853	1.00
85_L	88_S	0.852	1.00
432_R	446_Y	0.852	1.00
261_I	277_V	0.852	1.00
420_C	423_I	0.849	1.00
256_F	260_A	0.848	1.00
82_T	319_N	0.848	1.00
411_P	415_F	0.847	1.00
326_L	337_N	0.844	1.00
447_A	450_H	0.843	1.00
306_L	343_L	0.840	1.00
437_C	440_P	0.838	1.00
184_E	187_F	0.838	1.00
158_K	297_A	0.837	1.00
128_W	131_V	0.837	1.00
16_H	149_E	0.834	1.00
330_T	333_G	0.833	1.00
398_N	403_R	0.833	1.00
75_G	79_A	0.832	1.00
336_M	340_L	0.831	1.00
70_A	401_E	0.830	1.00
423_I	427_F	0.830	1.00
86_G	450_H	0.829	1.00
8_L	311_R	0.826	1.00
270_I	273_P	0.826	1.00
440_P	447_A	0.824	1.00
97_Y	101_W	0.819	1.00
58_Y	62_L	0.819	1.00
107_L	214_F	0.819	1.00
15_R	152_F	0.818	1.00
75_G	78_Q	0.815	1.00
8_L	228_E	0.812	1.00
430_D	436_Y	0.810	1.00
149_E	152_F	0.810	1.00
54_G	216_F	0.808	1.00
107_L	365_I	0.806	1.00
138_L	141_A	0.800	1.00
14_S	239_S	0.794	1.00
126_W	350_L	0.792	1.00
431_Q	436_Y	0.792	1.00
322_G	326_L	0.790	1.00
185_T	191_F	0.787	1.00
112_A	298_I	0.787	1.00
343_L	347_G	0.787	1.00
117_Q	121_P	0.786	1.00
116_M	295_L	0.785	1.00
221_L	308_A	0.784	1.00
89_T	378_S	0.784	1.00
165_F	278_L	0.783	1.00
207_F	211_M	0.781	1.00
441_I	449_Y	0.781	1.00
58_Y	241_R	0.780	1.00
430_D	443_I	0.779	1.00
110_T	364_C	0.778	1.00
195_R	199_P	0.777	1.00
384_F	411_P	0.775	1.00
273_P	277_V	0.773	1.00
171_A	174_F	0.760	1.00
136_I	306_L	0.752	1.00
59_L	63_C	0.748	1.00
67_L	383_Q	0.748	1.00
443_I	446_Y	0.748	1.00
51_I	55_F	0.747	1.00
344_G	347_G	0.739	1.00
367_I	371_V	0.739	1.00
186_P	191_F	0.738	1.00
81_A	382_S	0.738	1.00
25_V	243_V	0.738	1.00
142_L	146_S	0.737	1.00
384_F	388_R	0.736	1.00
112_A	299_L	0.735	1.00
421_V	425_L	0.735	1.00
435_L	439_V	0.731	1.00
11_S	144_V	0.729	1.00
432_R	438_G	0.729	1.00
440_P	445_C	0.729	1.00
285_F	288_D	0.727	1.00
109_L	113_G	0.726	1.00
130_L	351_L	0.725	1.00
43_P	259_V	0.725	1.00
185_T	189_S	0.721	1.00
390_F	398_N	0.721	1.00
102_A	345_I	0.721	1.00
48_A	205_V	0.719	1.00
133_G	350_L	0.716	1.00
173_V	257_V	0.715	1.00
382_S	386_F	0.714	1.00
67_L	80_Y	0.713	1.00
170_G	253_L	0.713	1.00
434_G	440_P	0.711	1.00
15_R	149_E	0.710	1.00
202_V	206_M	0.710	1.00
425_L	429_P	0.708	1.00
30_L	254_A	0.708	1.00
433_I	438_G	0.708	1.00
331_K	336_M	0.706	1.00
18_F	239_S	0.704	1.00
407_Y	410_V	0.701	1.00
410_V	414_G	0.700	1.00
217_Q	376_W	0.699	1.00
434_G	439_V	0.699	1.00
95_W	440_P	0.699	1.00
126_W	129_C	0.699	1.00
272_S	275_V	0.697	1.00
88_S	92_M	0.694	1.00
166_I	254_A	0.694	1.00
448_Y	451_L	0.694	1.00
444_F	449_Y	0.691	1.00
141_A	339_L	0.689	1.00
57_M	219_T	0.689	1.00
48_A	52_I	0.689	1.00
431_Q	444_F	0.688	1.00
311_R	314_W	0.684	1.00
190_N	193_T	0.684	1.00
148_A	152_F	0.684	1.00
384_F	408_P	0.683	1.00
237_P	240_I	0.682	1.00
187_F	193_T	0.682	1.00
435_L	445_C	0.680	1.00
231_S	237_P	0.680	1.00
84_F	385_F	0.678	1.00
399_D	403_R	0.677	1.00
435_L	440_P	0.677	1.00
310_S	338_A	0.673	1.00
436_Y	441_I	0.672	1.00
326_L	338_A	0.671	1.00
189_S	192_M	0.671	1.00
60_V	418_Y	0.669	1.00
436_Y	439_V	0.668	1.00
335_P	338_A	0.667	1.00
15_R	18_F	0.666	1.00
141_A	332_K	0.664	1.00
278_L	281_I	0.664	1.00
24_G	305_G	0.663	1.00
26_I	158_K	0.662	1.00
430_D	447_A	0.661	1.00
433_I	443_I	0.659	1.00
27_G	31_F	0.659	1.00
106_G	364_C	0.658	1.00
404_T	407_Y	0.655	1.00
432_R	450_H	0.655	1.00
48_A	51_I	0.655	1.00
118_R	291_N	0.654	1.00
233_E	401_E	0.653	1.00
433_I	444_F	0.653	1.00
146_S	149_E	0.651	1.00
390_F	400_L	0.651	1.00
85_L	90_G	0.650	1.00
24_G	304_S	0.650	1.00
23_G	155_S	0.648	1.00
104_T	368_S	0.647	1.00
173_V	176_L	0.645	1.00
424_S	428_I	0.643	1.00
168_I	172_A	0.643	1.00
313_M	341_I	0.643	1.00
423_I	426_I	0.642	1.00
267_A	270_I	0.641	1.00
61_M	219_T	0.641	1.00
325_F	341_I	0.640	1.00
246_R	249_F	0.639	1.00
436_Y	448_Y	0.638	1.00
246_R	250_F	0.638	1.00
96_L	375_A	0.638	1.00
47_I	51_I	0.636	1.00
64_L	379_I	0.635	1.00
62_L	410_V	0.635	1.00
430_D	445_C	0.634	1.00
18_F	21_A	0.634	1.00
140_N	339_L	0.634	1.00
101_W	305_G	0.634	1.00
11_S	15_R	0.632	1.00
78_Q	82_T	0.632	1.00
34_S	255_M	0.630	1.00
411_P	425_L	0.630	1.00
223_G	240_I	0.630	1.00
70_A	391_L	0.629	1.00
417_L	421_V	0.628	1.00
113_G	116_M	0.628	1.00
103_N	367_I	0.626	1.00
383_Q	387_R	0.623	1.00
104_T	107_L	0.621	1.00
306_L	310_S	0.621	1.00
273_P	281_I	0.621	1.00
405_P	409_L	0.620	1.00
132_F	302_A	0.618	1.00
74_A	314_W	0.617	1.00
102_A	342_T	0.616	1.00
116_M	132_F	0.616	1.00
253_L	257_V	0.616	1.00
191_F	194_D	0.615	1.00
59_L	414_G	0.615	1.00
84_F	386_F	0.615	1.00
100_S	372_T	0.614	1.00
439_V	442_I	0.614	1.00
46_A	255_M	0.612	1.00
436_Y	444_F	0.611	1.00
421_V	424_S	0.610	1.00
185_T	190_N	0.609	1.00
134_I	137_F	0.609	1.00
65_G	69_V	0.606	1.00
78_Q	94_G	0.605	1.00
414_G	417_L	0.603	1.00
431_Q	438_G	0.602	1.00
108_E	111_S	0.602	1.00
26_I	31_F	0.600	1.00
36_F	362_L	0.598	1.00
190_N	197_L	0.598	1.00
67_L	84_F	0.598	1.00
317_S	326_L	0.598	1.00
432_R	441_I	0.597	1.00
206_M	424_S	0.597	1.00
157_I	293_V	0.596	1.00
436_Y	442_I	0.596	1.00
144_V	225_A	0.595	1.00
309_A	313_M	0.594	1.00
68_A	223_G	0.592	1.00
85_L	382_S	0.592	1.00
227_G	314_W	0.591	1.00
136_I	299_L	0.589	1.00
254_A	274_F	0.589	1.00
40_Q	43_P	0.587	1.00
236_L	240_I	0.587	1.00
140_N	307_Y	0.587	1.00
438_G	441_I	0.585	1.00
157_I	161_A	0.585	1.00
232_P	235_T	0.583	1.00
224_I	308_A	0.583	1.00
217_Q	220_E	0.582	1.00
437_C	441_I	0.578	1.00
77_F	220_E	0.578	1.00
63_C	414_G	0.578	1.00
434_G	443_I	0.577	1.00
434_G	437_C	0.577	1.00
115_L	294_I	0.576	1.00
267_A	273_P	0.576	1.00
190_N	195_R	0.574	1.00
33_G	365_I	0.573	1.00
440_P	449_Y	0.573	1.00
434_G	447_A	0.572	1.00
133_G	347_G	0.571	1.00
432_R	439_V	0.571	1.00
47_I	252_V	0.571	1.00
155_S	158_K	0.571	1.00
68_A	236_L	0.570	1.00
50_Y	215_S	0.569	1.00
119_W	292_F	0.568	1.00
441_I	448_Y	0.567	1.00
432_R	449_Y	0.566	1.00
152_F	156_S	0.566	1.00
421_V	426_I	0.565	1.00
411_P	418_Y	0.565	1.00
204_A	207_F	0.562	1.00
254_A	258_L	0.561	1.00
143_S	146_S	0.558	1.00
411_P	417_L	0.556	1.00
443_I	449_Y	0.555	1.00
8_L	11_S	0.554	1.00
148_A	303_N	0.553	1.00
430_D	449_Y	0.552	1.00
431_Q	440_P	0.551	1.00
119_W	291_N	0.550	1.00
292_F	296_T	0.550	1.00
78_Q	90_G	0.548	1.00
228_E	335_P	0.548	1.00
386_F	390_F	0.547	1.00
106_G	349_S	0.546	1.00
433_I	446_Y	0.544	1.00
108_E	302_A	0.543	1.00
53_G	213_N	0.542	1.00
269_V	273_P	0.541	1.00
402_F	405_P	0.541	1.00
436_Y	446_Y	0.540	1.00
36_F	40_Q	0.540	1.00
229_S	236_L	0.538	1.00
30_L	33_G	0.536	1.00
27_G	251_F	0.536	1.00
21_A	25_V	0.534	1.00
400_L	404_T	0.534	1.00
289_I	293_V	0.534	1.00
391_L	398_N	0.532	1.00
242_N	245_W	0.532	1.00
106_G	109_L	0.532	1.00
115_L	275_V	0.531	1.00
169_G	173_V	0.530	1.00
347_G	350_L	0.530	1.00
118_R	121_P	0.530	1.00
37_T	212_V	0.530	1.00
194_D	197_L	0.528	1.00
40_Q	207_F	0.528	1.00
313_M	317_S	0.528	1.00
233_E	399_D	0.528	1.00
348_C	351_L	0.525	1.00
351_L	354_V	0.525	1.00
406_L	411_P	0.525	1.00
373_V	418_Y	0.525	1.00
171_A	176_L	0.525	1.00
329_L	332_K	0.524	1.00
61_M	65_G	0.523	1.00
297_A	300_S	0.523	1.00
193_T	197_L	0.523	1.00
153_W	156_S	0.523	1.00
49_A	52_I	0.522	1.00
188_L	260_A	0.521	1.00
311_R	329_L	0.521	1.00
108_E	298_I	0.520	1.00
336_M	339_L	0.520	1.00
47_I	50_Y	0.519	1.00
98_W	102_A	0.519	1.00
441_I	444_F	0.518	1.00
437_C	445_C	0.518	1.00
271_E	275_V	0.518	1.00
168_I	283_I	0.517	1.00
147_F	307_Y	0.517	1.00
104_T	108_E	0.517	1.00
77_F	224_I	0.516	1.00
258_L	274_F	0.516	1.00
274_F	278_L	0.516	1.00
44_L	197_L	0.515	1.00
431_Q	441_I	0.515	1.00
432_R	443_I	0.515	1.00
372_T	375_A	0.515	1.00
371_V	375_A	0.514	1.00
131_V	134_I	0.514	1.00
441_I	447_A	0.514	1.00
416_C	419_G	0.513	1.00
193_T	196_G	0.513	1.00
10_R	230_E	0.511	1.00
52_I	209_L	0.510	1.00
186_P	192_M	0.510	1.00
112_A	116_M	0.510	1.00
26_I	250_F	0.509	1.00
415_F	418_Y	0.509	1.00
53_G	216_F	0.508	1.00
269_V	272_S	0.508	1.00
134_I	340_L	0.507	1.00
325_F	329_L	0.505	1.00
43_P	47_I	0.505	1.00
146_S	150_M	0.505	1.00
275_V	279_D	0.504	1.00
189_S	193_T	0.504	1.00
386_F	391_L	0.503	1.00
22_L	155_S	0.503	1.00
151_E	300_S	0.503	1.00
76_S	223_G	0.503	1.00
111_S	115_L	0.503	1.00
132_F	299_L	0.503	1.00
362_L	365_I	0.503	1.00
192_M	195_R	0.502	1.00
217_Q	368_S	0.501	1.00
418_Y	422_L	0.501	1.00
96_L	100_S	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.8872	100	0.307	Contact Map
4djkA	2	0.8766	100	0.36	Contact Map
3giaA	1	0.9021	100	0.371	Contact Map
3dh4A	3	0.917	99.1	0.848	Contact Map
2xq2A	2	0.9191	99.1	0.852	Contact Map
2jlnA	1	0.9	98.9	0.86	Contact Map
2a65A	2	0.9106	98.3	0.888	Contact Map
4xp4A	1	0.9362	98.1	0.892	Contact Map
4wgvA	2	0.7872	97.4	0.907	Contact Map
4us3A	1	0.8404	97.2	0.911	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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