ALDH2 - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

ALDH2 - Probable aldehyde dehydrogenase YwdH

UniProt:	P39616	Sequences: MNSIPSIISKHKAYFAAGHTRPLESRLNILRKLKQAVRTHEADLIAALYQDLHKSEQEAYSTEIGIVLEEISFVMKRLRKWSKPKRVKTPLTHLGSKSIIIPEPYGTVLVIAPWNYPLQLALSPLIGAIAAGNTVVLKPSEYTPAVSAILSKLISSVFPTDYVAMAEGGPDVSTALLQQPFDYIFFTGSVAVGKIVMEAAAKQLIPVTLELGGKSPCIVHKDADIQLAAKRIVFGKFTNAGQTCIAPDYLFVHEDIKTKLTEEMKRAIREFYGPQPERNPQYGKIVSERHYQRLLSFLNDGIPLTGGQSDPNHHKIAPTILEQVRDDSPVMQEEIFGPILPLFTYRNIGEVIEKVQSRPKPLALYLFTTNKEIERAVLGNLSFGGGCVNDTLMHVATPYLPFGGVGESGIGSYHGFDSFNTFTHKKSVVKQTNRFDFAFRYPSSKNGLRMIRKILK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	456 (422)
Sequences:	35374 (20773)
Seq/√Len:	1011.2

ECOLI - GABD PUUC BETB ABDH ALDB FEAB ALDA ASTD SAD EUTE PUTA PROA PAAZ ADHE
BACSU - ALDH2 ROCA2 ROCA ALDH1 ALDH4 ALDH5 IOLA ALDH3 GABD ALDY BETB PROA
HALSA - Q9HMJ6 Q9HQZ2 Q9HR91 Q9HRB5
SULSO - Q97YT9 Q97XS9 GAPN KGSDH Q97XA5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
254_E	346_R	5.347	1.00
198_E	202_K	4.015	1.00
254_E	344_T	3.330	1.00
226_Q	263_E	3.303	1.00
257_K	344_T	3.036	1.00
325_R	328_S	3.019	1.00
221_K	253_H	2.878	1.00
308_Q	317_A	2.833	1.00
288_E	292_Q	2.733	1.00
261_T	342_L	2.652	1.00
230_K	267_A	2.628	1.00
38_R	72_S	2.599	1.00
300_D	329_P	2.588	1.00
149_I	152_K	2.579	1.00
12_K	182_D	2.511	1.00
221_K	255_D	2.493	1.00
40_H	43_D	2.475	1.00
298_L	316_I	2.435	1.00
368_T	374_E	2.339	1.00
33_L	154_I	2.255	1.00
42_A	60_Y	2.238	1.00
155_S	160_T	2.193	1.00
41_E	65_G	2.165	1.00
103_E	426_K	2.139	1.00
348_I	373_I	2.129	1.00
295_L	299_N	2.100	1.00
285_I	294_L	2.070	1.00
265_K	269_R	2.017	1.00
142_Y	287_S	2.005	1.00
359_P	407_E	1.994	1.00
217_C	232_I	1.993	1.00
174_T	178_Q	1.993	1.00
321_L	330_V	1.970	1.00
29_I	158_F	1.949	1.00
102_P	420_N	1.941	1.00
376_A	380_N	1.940	1.00
178_Q	199_A	1.939	1.00
295_L	309_S	1.937	1.00
295_L	316_I	1.919	1.00
43_D	149_I	1.914	1.00
222_D	373_I	1.891	1.00
259_K	263_E	1.882	1.00
348_I	376_A	1.879	1.00
251_F	354_K	1.871	1.00
251_F	351_V	1.863	1.00
102_P	423_T	1.831	1.00
382_S	406_G	1.825	1.00
5_P	175_A	1.816	1.00
195_I	198_E	1.802	1.00
36_A	153_L	1.793	1.00
253_H	345_Y	1.786	1.00
194_K	407_E	1.775	1.00
326_D	354_K	1.751	1.00
304_L	322_E	1.750	1.00
331_M	343_F	1.738	1.00
268_I	320_I	1.736	1.00
36_A	39_T	1.736	1.00
151_S	165_M	1.690	1.00
329_P	333_E	1.671	1.00
15_F	19_H	1.666	1.00
232_I	260_L	1.658	1.00
47_A	149_I	1.655	1.00
134_T	162_Y	1.648	1.00
71_I	126_I	1.645	1.00
225_I	263_E	1.641	1.00
257_K	261_T	1.636	1.00
31_R	72_S	1.633	1.00
237_F	268_I	1.633	1.00
250_L	340_L	1.631	1.00
350_E	353_E	1.621	1.00
5_P	9_S	1.614	1.00
258_T	344_T	1.611	1.00
262_E	266_R	1.592	1.00
36_A	156_S	1.588	1.00
22_P	25_S	1.578	1.00
5_P	179_Q	1.577	1.00
35_Q	39_T	1.570	1.00
346_R	350_E	1.567	1.00
56_E	60_Y	1.564	1.00
349_G	380_N	1.555	1.00
296_S	329_P	1.541	1.00
38_R	68_L	1.539	1.00
221_K	373_I	1.538	1.00
35_Q	72_S	1.533	1.00
265_K	304_L	1.517	1.00
257_K	322_E	1.517	1.00
297_F	335_I	1.514	1.00
364_L	383_F	1.507	1.00
263_E	266_R	1.504	1.00
31_R	79_R	1.499	1.00
288_E	314_H	1.486	1.00
8_I	179_Q	1.481	1.00
251_F	345_Y	1.479	1.00
25_S	28_N	1.476	1.00
77_R	80_K	1.473	1.00
229_A	263_E	1.466	1.00
231_R	367_F	1.465	1.00
252_V	260_L	1.454	1.00
32_K	35_Q	1.444	1.00
220_H	373_I	1.443	1.00
42_A	46_A	1.437	1.00
49_Y	59_A	1.428	1.00
46_A	50_Q	1.426	1.00
34_K	72_S	1.424	1.00
232_I	250_L	1.419	1.00
71_I	122_L	1.418	1.00
20_T	380_N	1.412	1.00
41_E	60_Y	1.411	1.00
267_A	270_E	1.408	1.00
110_V	135_V	1.405	1.00
259_K	262_E	1.402	1.00
220_H	345_Y	1.392	1.00
350_E	354_K	1.375	1.00
197_M	410_I	1.375	1.00
101_I	379_G	1.362	1.00
15_F	134_T	1.353	1.00
46_A	276_P	1.351	1.00
183_Y	208_T	1.344	1.00
40_H	149_I	1.342	1.00
141_E	170_P	1.342	1.00
291_Y	316_I	1.334	1.00
151_S	163_V	1.319	1.00
345_Y	354_K	1.310	1.00
121_A	137_L	1.298	1.00
21_R	25_S	1.295	1.00
174_T	199_A	1.291	1.00
299_N	303_P	1.288	1.00
3_S	6_S	1.284	1.00
352_I	377_V	1.280	1.00
154_I	163_V	1.279	1.00
258_T	262_E	1.275	1.00
347_N	350_E	1.272	1.00
220_H	377_V	1.272	1.00
44_L	149_I	1.267	1.00
266_R	269_R	1.266	1.00
294_L	337_G	1.264	1.00
161_D	164_A	1.260	1.00
261_T	265_K	1.254	1.00
34_K	38_R	1.250	1.00
4_I	172_V	1.249	1.00
291_Y	295_L	1.246	1.00
292_Q	296_S	1.237	1.00
253_H	256_I	1.233	1.00
273_G	280_P	1.223	1.00
178_Q	202_K	1.220	1.00
33_L	153_L	1.219	1.00
291_Y	309_S	1.218	1.00
417_D	420_N	1.214	1.00
253_H	347_N	1.213	1.00
264_M	340_L	1.211	1.00
288_E	291_Y	1.211	1.00
271_F	282_Y	1.210	1.00
174_T	195_I	1.208	1.00
49_Y	275_Q	1.207	1.00
32_K	36_A	1.196	1.00
10_K	164_A	1.187	1.00
327_D	332_Q	1.186	1.00
296_S	300_D	1.179	1.00
102_P	425_K	1.177	1.00
218_I	351_V	1.176	1.00
33_L	71_I	1.174	1.00
99_I	375_R	1.174	1.00
364_L	386_G	1.172	1.00
332_Q	357_S	1.169	1.00
260_L	264_M	1.165	1.00
378_L	428_V	1.163	1.00
374_E	388_V	1.159	1.00
125_L	163_V	1.157	1.00
326_D	357_S	1.157	1.00
192_V	195_I	1.155	1.00
416_F	420_N	1.154	1.00
46_A	56_E	1.150	1.00
175_A	179_Q	1.149	1.00
256_I	259_K	1.147	1.00
21_R	29_I	1.147	1.00
33_L	158_F	1.146	1.00
110_V	185_F	1.143	1.00
109_L	176_L	1.141	1.00
269_R	305_T	1.136	1.00
266_R	270_E	1.132	1.00
40_H	153_L	1.130	1.00
8_I	181_F	1.128	1.00
261_T	322_E	1.125	1.00
217_C	247_P	1.121	1.00
9_S	13_A	1.119	1.00
214_K	248_D	1.115	1.00
263_E	267_A	1.115	1.00
403_G	412_S	1.106	1.00
332_Q	359_P	1.106	1.00
218_I	377_V	1.103	1.00
224_D	369_T	1.102	1.00
105_Y	183_Y	1.098	1.00
269_R	317_A	1.096	1.00
31_R	76_K	1.095	1.00
297_F	300_D	1.093	1.00
349_G	376_A	1.091	1.00
148_A	167_E	1.088	1.00
195_I	199_A	1.087	1.00
116_Y	243_T	1.086	1.00
348_I	377_V	1.086	1.00
291_Y	314_H	1.084	1.00
306_G	319_T	1.077	1.00
294_L	339_I	1.074	1.00
191_A	195_I	1.073	1.00
417_D	425_K	1.071	1.00
197_M	207_V	1.070	1.00
352_I	380_N	1.065	1.00
412_S	424_H	1.061	1.00
148_A	165_M	1.057	1.00
14_Y	134_T	1.056	1.00
299_N	302_I	1.053	1.00
84_P	417_D	1.050	1.00
194_K	204_L	1.049	1.00
125_L	135_V	1.049	1.00
218_I	355_V	1.049	1.00
44_L	153_L	1.048	1.00
370_N	373_I	1.044	1.00
109_L	181_F	1.042	1.00
101_I	428_V	1.041	1.00
84_P	416_F	1.036	1.00
216_P	364_L	1.034	1.00
16_A	353_E	1.029	1.00
258_T	261_T	1.020	1.00
197_M	201_A	1.016	1.00
27_L	79_R	1.014	1.00
324_V	328_S	1.011	1.00
224_D	227_L	1.010	1.00
107_T	181_F	1.007	1.00
274_P	277_E	1.007	1.00
349_G	353_E	1.000	1.00
345_Y	351_V	0.993	1.00
16_A	20_T	0.993	1.00
265_K	305_T	0.988	1.00
16_A	382_S	0.979	1.00
105_Y	206_P	0.972	1.00
182_D	382_S	0.967	1.00
45_I	60_Y	0.967	1.00
67_V	122_L	0.965	1.00
54_K	63_E	0.965	1.00
405_V	424_H	0.953	1.00
297_F	329_P	0.952	1.00
235_G	247_P	0.952	1.00
226_Q	259_K	0.952	1.00
236_K	248_D	0.949	1.00
78_L	130_A	0.949	1.00
220_H	348_I	0.948	1.00
103_E	379_G	0.942	1.00
98_S	400_L	0.942	1.00
12_K	16_A	0.940	1.00
107_T	134_T	0.936	1.00
43_D	46_A	0.936	1.00
229_A	264_M	0.934	1.00
353_E	357_S	0.933	1.00
261_T	304_L	0.932	1.00
306_G	317_A	0.927	1.00
206_P	424_H	0.923	1.00
34_K	75_M	0.920	1.00
351_V	354_K	0.919	1.00
189_S	192_V	0.919	1.00
19_H	382_S	0.917	1.00
292_Q	295_L	0.917	1.00
343_F	354_K	0.913	1.00
52_L	143_T	0.911	1.00
257_K	342_L	0.911	1.00
50_Q	276_P	0.910	1.00
219_V	260_L	0.908	1.00
326_D	343_F	0.907	1.00
31_R	75_M	0.905	1.00
105_Y	133_N	0.903	1.00
227_L	231_R	0.903	1.00
27_L	75_M	0.902	1.00
108_V	183_Y	0.900	1.00
225_I	229_A	0.898	1.00
228_A	232_I	0.896	1.00
233_V	267_A	0.895	1.00
345_Y	350_E	0.894	1.00
23_L	27_L	0.892	1.00
103_E	405_V	0.892	1.00
217_C	367_F	0.890	1.00
366_L	377_V	0.890	1.00
301_G	321_L	0.889	1.00
229_A	267_A	0.888	1.00
229_A	260_L	0.885	1.00
257_K	323_Q	0.880	1.00
40_H	152_K	0.880	1.00
294_L	335_I	0.880	1.00
105_Y	424_H	0.878	1.00
364_L	381_L	0.877	1.00
158_F	163_V	0.876	1.00
400_L	427_S	0.875	1.00
99_I	430_K	0.874	1.00
27_L	31_R	0.872	1.00
10_K	161_D	0.871	1.00
37_V	67_V	0.867	1.00
184_I	196_V	0.866	1.00
220_H	368_T	0.865	1.00
109_L	173_S	0.864	1.00
194_K	198_E	0.864	1.00
168_G	172_V	0.863	1.00
152_K	155_S	0.861	1.00
4_I	109_L	0.858	1.00
28_N	32_K	0.857	1.00
197_M	200_A	0.855	1.00
215_S	248_D	0.855	1.00
298_L	339_I	0.850	1.00
229_A	233_V	0.847	1.00
124_P	413_Y	0.845	1.00
14_Y	162_Y	0.845	1.00
36_A	40_H	0.845	1.00
228_A	260_L	0.844	1.00
32_K	156_S	0.840	1.00
30_L	130_A	0.840	1.00
142_Y	289_R	0.835	1.00
67_V	118_L	0.835	1.00
375_R	379_G	0.834	1.00
322_E	344_T	0.832	1.00
233_V	264_M	0.830	1.00
184_I	200_A	0.830	1.00
9_S	12_K	0.829	1.00
20_T	379_G	0.828	1.00
352_I	356_Q	0.828	1.00
127_G	418_S	0.828	1.00
177_L	196_V	0.824	1.00
197_M	204_L	0.819	1.00
298_L	321_L	0.817	1.00
193_G	211_L	0.815	1.00
37_V	68_L	0.813	1.00
6_S	10_K	0.812	1.00
121_A	125_L	0.810	1.00
137_L	147_S	0.808	1.00
49_Y	56_E	0.806	1.00
271_F	281_Q	0.805	1.00
109_L	184_I	0.804	1.00
296_S	299_N	0.804	1.00
170_P	174_T	0.803	1.00
302_I	321_L	0.802	1.00
13_A	16_A	0.801	1.00
303_P	323_Q	0.800	1.00
264_M	320_I	0.797	1.00
294_L	316_I	0.796	1.00
193_G	209_L	0.792	1.00
50_Q	145_A	0.791	1.00
262_E	265_K	0.788	1.00
383_F	386_G	0.788	1.00
216_P	355_V	0.788	1.00
371_K	374_E	0.786	1.00
128_A	135_V	0.786	1.00
24_E	79_R	0.785	1.00
139_P	167_E	0.782	1.00
173_S	177_L	0.780	1.00
52_L	286_V	0.779	1.00
148_A	152_K	0.778	1.00
131_A	423_T	0.777	1.00
45_I	56_E	0.776	1.00
321_L	324_V	0.776	1.00
110_V	124_P	0.775	1.00
11_H	164_A	0.774	1.00
45_I	49_Y	0.772	1.00
122_L	150_L	0.771	1.00
57_Q	281_Q	0.767	1.00
177_L	184_I	0.766	1.00
31_R	35_Q	0.765	1.00
177_L	199_A	0.763	1.00
252_V	256_I	0.762	1.00
371_K	430_K	0.761	1.00
13_A	17_A	0.761	1.00
133_N	423_T	0.760	1.00
60_Y	278_R	0.757	1.00
18_G	162_Y	0.757	1.00
253_H	348_I	0.753	1.00
220_H	253_H	0.751	1.00
16_A	19_H	0.750	1.00
168_G	173_S	0.749	1.00
158_F	162_Y	0.748	1.00
136_V	164_A	0.746	1.00
29_I	156_S	0.745	1.00
186_F	192_V	0.745	1.00
297_F	333_E	0.744	1.00
200_A	207_V	0.744	1.00
48_L	51_D	0.742	1.00
6_S	9_S	0.742	1.00
225_I	256_I	0.740	1.00
151_S	155_S	0.739	1.00
226_Q	267_A	0.737	1.00
265_K	268_I	0.736	1.00
268_I	271_F	0.736	1.00
141_E	293_R	0.735	1.00
190_V	407_E	0.734	1.00
44_L	118_L	0.732	1.00
4_I	175_A	0.732	1.00
54_K	58_E	0.729	1.00
56_E	276_P	0.728	1.00
277_E	280_P	0.726	1.00
347_N	353_E	0.724	1.00
121_A	147_S	0.724	1.00
170_P	195_I	0.721	1.00
307_G	319_T	0.721	1.00
194_K	202_K	0.721	1.00
118_L	146_V	0.719	1.00
2_N	5_P	0.717	1.00
137_L	163_V	0.716	1.00
142_Y	286_V	0.713	1.00
47_A	145_A	0.713	1.00
17_A	21_R	0.712	1.00
316_I	319_T	0.711	1.00
348_I	352_I	0.709	1.00
307_G	317_A	0.708	1.00
289_R	293_R	0.707	1.00
38_R	65_G	0.706	1.00
250_L	260_L	0.704	1.00
154_I	158_F	0.703	1.00
388_V	430_K	0.703	1.00
251_F	331_M	0.702	1.00
23_L	78_L	0.702	1.00
222_D	368_T	0.700	1.00
354_K	357_S	0.698	1.00
274_P	280_P	0.697	1.00
198_E	201_A	0.697	1.00
38_R	41_E	0.696	1.00
251_F	326_D	0.695	1.00
49_Y	276_P	0.694	1.00
36_A	157_V	0.693	1.00
290_H	293_R	0.692	1.00
287_S	290_H	0.692	1.00
326_D	331_M	0.691	1.00
149_I	153_L	0.690	1.00
2_N	6_S	0.689	1.00
12_K	15_F	0.687	1.00
18_G	29_I	0.686	1.00
134_T	164_A	0.686	1.00
175_A	178_Q	0.684	1.00
105_Y	182_D	0.683	1.00
42_A	56_E	0.683	1.00
11_H	134_T	0.683	1.00
98_S	427_S	0.682	1.00
19_H	380_N	0.680	1.00
141_E	195_I	0.677	1.00
268_I	305_T	0.675	1.00
112_A	121_A	0.672	1.00
4_I	8_I	0.672	1.00
369_T	372_E	0.671	1.00
43_D	152_K	0.671	1.00
324_V	331_M	0.671	1.00
264_M	342_L	0.671	1.00
240_A	282_Y	0.670	1.00
289_R	292_Q	0.670	1.00
64_I	68_L	0.669	1.00
48_L	63_E	0.668	1.00
171_D	174_T	0.666	1.00
232_I	264_M	0.665	1.00
99_I	428_V	0.662	1.00
121_A	150_L	0.661	1.00
206_P	421_T	0.660	1.00
54_K	116_Y	0.659	1.00
97_K	375_R	0.658	1.00
177_L	203_Q	0.658	1.00
19_H	103_E	0.656	1.00
378_L	388_V	0.654	1.00
17_A	20_T	0.654	1.00
208_T	421_T	0.654	1.00
10_K	160_T	0.653	1.00
265_K	320_I	0.653	1.00
124_P	185_F	0.653	1.00
374_E	378_L	0.652	1.00
335_I	339_I	0.651	1.00
285_I	290_H	0.649	1.00
29_I	157_V	0.646	1.00
324_V	330_V	0.646	1.00
34_K	68_L	0.645	1.00
35_Q	38_R	0.644	1.00
272_Y	282_Y	0.642	1.00
219_V	228_A	0.641	1.00
48_L	59_A	0.639	1.00
375_R	430_K	0.636	1.00
368_T	373_I	0.635	1.00
288_E	309_S	0.634	1.00
19_H	104_P	0.634	1.00
98_S	429_V	0.632	1.00
382_S	405_V	0.632	1.00
16_A	380_N	0.631	1.00
371_K	375_R	0.630	1.00
295_L	298_L	0.629	1.00
90_P	93_H	0.629	1.00
420_N	425_K	0.629	1.00
37_V	118_L	0.628	1.00
125_L	137_L	0.628	1.00
101_I	426_K	0.627	1.00
199_A	202_K	0.627	1.00
233_V	271_F	0.623	1.00
352_I	381_L	0.623	1.00
25_S	29_I	0.622	1.00
7_I	166_A	0.621	1.00
420_N	423_T	0.620	1.00
18_G	129_I	0.619	1.00
352_I	376_A	0.618	1.00
366_L	374_E	0.618	1.00
225_I	259_K	0.617	1.00
41_E	45_I	0.615	1.00
305_T	320_I	0.614	1.00
169_G	173_S	0.613	1.00
141_E	191_A	0.613	1.00
46_A	49_Y	0.612	1.00
386_G	426_K	0.612	1.00
217_C	250_L	0.611	1.00
14_Y	17_A	0.611	1.00
252_V	342_L	0.610	1.00
23_L	130_A	0.609	1.00
293_R	296_S	0.609	1.00
217_C	365_Y	0.603	1.00
33_L	36_A	0.602	1.00
37_V	71_I	0.602	1.00
64_I	118_L	0.602	1.00
183_Y	421_T	0.602	1.00
197_M	209_L	0.601	1.00
222_D	370_N	0.601	1.00
37_V	150_L	0.600	1.00
48_L	146_V	0.599	1.00
222_D	369_T	0.599	1.00
372_E	376_A	0.599	1.00
272_Y	281_Q	0.597	1.00
235_G	391_T	0.594	1.00
243_T	246_A	0.593	1.00
227_L	230_K	0.592	1.00
81_W	423_T	0.592	1.00
323_Q	344_T	0.592	1.00
32_K	157_V	0.588	1.00
37_V	44_L	0.587	1.00
221_K	345_Y	0.586	1.00
29_I	33_L	0.585	1.00
223_A	228_A	0.584	1.00
34_K	71_I	0.584	1.00
73_F	77_R	0.584	1.00
227_L	369_T	0.582	1.00
44_L	64_I	0.582	1.00
372_E	375_R	0.582	1.00
150_L	154_I	0.581	1.00
245_I	395_V	0.579	1.00
108_V	133_N	0.578	1.00
118_L	150_L	0.578	1.00
12_K	107_T	0.576	1.00
108_V	135_V	0.576	1.00
216_P	383_F	0.574	1.00
331_M	354_K	0.573	1.00
285_I	316_I	0.573	1.00
303_P	322_E	0.573	1.00
119_Q	123_S	0.572	1.00
81_W	419_F	0.572	1.00
191_A	289_R	0.571	1.00
210_E	362_L	0.571	1.00
136_V	166_A	0.570	1.00
11_H	136_V	0.568	1.00
141_E	169_G	0.568	1.00
110_V	125_L	0.568	1.00
109_L	136_V	0.567	1.00
247_P	365_Y	0.566	1.00
190_V	194_K	0.565	1.00
180_P	359_P	0.565	1.00
131_A	419_F	0.563	1.00
351_V	355_V	0.562	1.00
309_S	317_A	0.560	1.00
355_V	381_L	0.560	1.00
254_E	257_K	0.558	1.00
229_A	256_I	0.557	1.00
225_I	228_A	0.556	1.00
65_G	68_L	0.556	1.00
107_T	182_D	0.555	1.00
45_I	64_I	0.554	1.00
250_L	342_L	0.553	1.00
66_I	119_Q	0.552	1.00
7_I	164_A	0.550	1.00
387_C	390_D	0.550	1.00
236_K	340_L	0.546	1.00
11_H	107_T	0.546	1.00
74_V	127_G	0.545	1.00
109_L	177_L	0.545	1.00
207_V	410_I	0.544	1.00
381_L	386_G	0.542	1.00
377_V	381_L	0.542	1.00
169_G	172_V	0.541	1.00
215_S	363_A	0.540	1.00
66_I	396_A	0.540	1.00
41_E	68_L	0.538	1.00
256_I	345_Y	0.537	1.00
363_A	387_C	0.535	1.00
262_E	269_R	0.535	1.00
63_E	116_Y	0.535	1.00
52_L	239_N	0.535	1.00
10_K	14_Y	0.535	1.00
366_L	388_V	0.535	1.00
348_I	380_N	0.535	1.00
111_I	196_V	0.534	1.00
5_P	8_I	0.533	1.00
108_V	185_F	0.533	1.00
382_S	424_H	0.532	1.00
264_M	268_I	0.532	1.00
76_K	79_R	0.531	1.00
12_K	179_Q	0.531	1.00
129_I	163_V	0.531	1.00
115_N	336_F	0.530	1.00
85_K	100_I	0.528	1.00
225_I	260_L	0.528	1.00
330_V	335_I	0.527	1.00
320_I	340_L	0.527	1.00
297_F	330_V	0.526	1.00
252_V	257_K	0.524	1.00
45_I	59_A	0.524	1.00
237_F	271_F	0.524	1.00
9_S	179_Q	0.524	1.00
239_N	243_T	0.523	1.00
8_I	175_A	0.521	1.00
53_H	283_G	0.521	1.00
144_P	167_E	0.521	1.00
129_I	158_F	0.520	1.00
302_I	308_Q	0.519	1.00
326_D	353_E	0.518	1.00
4_I	166_A	0.518	1.00
326_D	332_Q	0.517	1.00
201_A	204_L	0.517	1.00
24_E	28_N	0.515	1.00
273_G	277_E	0.514	1.00
300_D	303_P	0.513	1.00
298_L	319_T	0.511	1.00
261_T	320_I	0.510	1.00
185_F	422_F	0.510	1.00
226_Q	266_R	0.509	1.00
54_K	59_A	0.508	1.00
174_T	177_L	0.508	1.00
103_E	382_S	0.505	1.00
77_R	416_F	0.504	1.00
410_I	424_H	0.504	1.00
15_F	162_Y	0.503	1.00
23_L	82_S	0.502	1.00
219_V	223_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3szaA	2	0.9868	100	0.065	Contact Map
4qgkA	2	0.9956	100	0.069	Contact Map
3ek1A	5	0.9364	100	0.085	Contact Map
1a4sA	4	0.9474	100	0.086	Contact Map
4o5hA	4	0.9452	100	0.087	Contact Map
4pxlA	4	0.9474	100	0.088	Contact Map
3u4jA	4	0.9518	100	0.089	Contact Map
4lihA	5	0.9364	100	0.089	Contact Map
1wndA	4	0.9364	100	0.089	Contact Map
4qf6A	4	0.9364	100	0.089	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0123 seconds.