GREMLIN Database
YWBO - Uncharacterized protein YwbO
UniProt: P39598 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 200 (189)
Sequences: 4554 (3530)
Seq/√Len: 256.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
119_Q129_K3.5241.00
29_G190_E3.0011.00
112_Q117_E2.9811.00
109_R133_E2.8121.00
4_H35_E2.7021.00
6_K35_E2.6631.00
4_H33_E2.5721.00
128_T142_K2.5151.00
132_E138_G2.5091.00
172_T179_V2.5021.00
6_K37_M2.4611.00
22_A72_L2.4601.00
89_L124_I2.3271.00
100_Y140_S2.2081.00
106_Y134_V2.1671.00
124_I146_E2.0991.00
11_Y94_F2.0451.00
11_Y90_A2.0441.00
55_P59_Y2.0181.00
159_K164_E2.0111.00
20_K24_E1.9101.00
99_E153_V1.9001.00
119_Q126_I1.8641.00
152_D156_Q1.8151.00
21_A108_T1.8111.00
102_K105_E1.8081.00
88_D155_R1.8001.00
120_N123_D1.7691.00
131_A141_F1.7451.00
113_A130_L1.6971.00
106_Y110_V1.6771.00
80_N118_D1.6761.00
20_K108_T1.6751.00
138_G142_K1.6601.00
137_D140_S1.6391.00
109_R130_L1.6121.00
9_S107_N1.5791.00
88_D151_Q1.5781.00
93_G106_Y1.5511.00
94_F107_N1.5131.00
38_P157_A1.4791.00
27_I32_V1.4771.00
98_K103_G1.4511.00
129_K138_G1.4331.00
93_G141_F1.4281.00
5_I23_F1.4221.00
109_R117_E1.4101.00
37_M160_H1.4031.00
95_H157_A1.3901.00
160_H165_A1.3581.00
173_F189_F1.3571.00
40_E158_L1.3511.00
148_R152_D1.3451.00
75_E116_Q1.3081.00
97_A101_N1.3011.00
77_N80_N1.3001.00
113_A119_Q1.2971.00
142_K146_E1.2901.00
94_F106_Y1.2811.00
112_Q116_Q1.2801.00
37_M157_A1.2781.00
36_W104_H1.2431.00
125_D142_K1.2391.00
113_A126_I1.2381.00
107_N111_F1.2371.00
190_E194_S1.2251.00
35_E98_K1.2121.00
6_K177_D1.1951.00
53_N57_K1.1571.00
156_Q160_H1.1551.00
24_E108_T1.1521.00
130_L134_V1.1461.00
99_E150_Y1.1321.00
175_I192_A1.1211.00
54_D57_K1.1191.00
128_T138_G1.1121.00
25_E72_L1.1091.00
124_I128_T1.0921.00
11_Y107_N1.0871.00
22_A185_G1.0821.00
93_G127_L1.0751.00
109_R134_V1.0671.00
184_A188_V1.0621.00
128_T132_E1.0621.00
144_A150_Y1.0611.00
90_A121_I1.0551.00
38_P95_H1.0481.00
42_R45_P1.0141.00
23_F34_V1.0131.00
66_Q70_E1.0131.00
64_S67_P1.0121.00
165_A174_I1.0081.00
89_L92_E1.0011.00
139_A143_S0.9991.00
129_K133_E0.9931.00
25_E28_K0.9861.00
140_S143_S0.9851.00
60_M64_S0.9711.00
169_A172_T0.9671.00
63_T67_P0.9641.00
110_V127_L0.9561.00
95_H98_K0.9521.00
97_A136_L0.9511.00
12_V87_T0.9511.00
16_C170_V0.9511.00
109_R112_Q0.9501.00
69_A76_I0.9481.00
180_I192_A0.9471.00
11_Y110_V0.9451.00
159_K163_E0.9411.00
92_E148_R0.9411.00
40_E88_D0.9391.00
126_I129_K0.9281.00
96_F144_A0.9261.00
25_E29_G0.9231.00
8_Y161_A0.9221.00
129_K132_E0.9201.00
77_N118_D0.9191.00
15_F68_M0.9131.00
59_Y63_T0.9121.00
61_W65_I0.9121.00
174_I179_V0.9071.00
87_T91_F0.9061.00
153_V156_Q0.9051.00
140_S144_A0.9041.00
64_S68_M0.8981.00
160_H164_E0.8981.00
26_A186_K0.8961.00
69_A74_V0.8861.00
57_K60_M0.8821.00
175_I189_F0.8811.00
24_E104_H0.8781.00
143_S149_T0.8761.00
17_F116_Q0.8701.00
140_S149_T0.8601.00
155_R158_L0.8550.99
96_F150_Y0.8520.99
65_I76_I0.8490.99
36_W107_N0.8440.99
47_P89_L0.8440.99
110_V121_I0.8430.99
186_K190_E0.8280.99
22_A68_M0.8260.99
25_E186_K0.8170.99
188_V191_K0.8160.99
58_Q62_Q0.8150.99
19_G173_F0.8100.99
96_F100_Y0.8070.99
67_P70_E0.8070.99
40_E155_R0.8030.99
21_A24_E0.8020.99
106_Y131_A0.8010.99
8_Y174_I0.7990.99
81_V118_D0.7980.99
39_F170_V0.7980.99
18_V65_I0.7980.99
70_E75_E0.7930.99
20_K104_H0.7810.99
17_F74_V0.7760.99
123_D126_I0.7740.99
109_R113_A0.7670.99
110_V130_L0.7630.99
160_H177_D0.7620.99
20_K36_W0.7620.99
39_F44_S0.7600.99
142_K145_L0.7540.99
169_A181_P0.7420.99
61_W64_S0.7410.99
63_T66_Q0.7380.98
95_H150_Y0.7380.98
9_S111_F0.7290.98
175_I193_I0.7280.98
57_K61_W0.7230.98
100_Y136_L0.7230.98
85_P122_G0.7230.98
143_S146_E0.7220.98
27_I34_V0.7180.98
30_K190_E0.7140.98
124_I142_K0.7110.98
94_F103_G0.7080.98
151_Q155_R0.7070.98
181_P184_A0.7070.98
143_S147_T0.7040.98
45_P49_L0.7040.98
172_T181_P0.7020.98
175_I180_I0.7000.98
40_E86_Y0.6990.98
22_A186_K0.6970.98
55_P58_Q0.6970.98
96_F141_F0.6940.98
21_A74_V0.6940.98
139_A142_K0.6930.98
44_S47_P0.6840.98
41_L87_T0.6810.97
93_G110_V0.6760.97
13_C16_C0.6720.97
5_I32_V0.6670.97
158_L163_E0.6620.97
191_K194_S0.6600.97
10_D87_T0.6590.97
7_V36_W0.6540.97
17_F112_Q0.6470.97
7_V173_F0.6460.97
21_A25_E0.6460.97
54_D58_Q0.6450.96
8_Y37_M0.6440.96
69_A78_F0.6420.96
8_Y38_P0.6420.96
147_T150_Y0.6410.96
56_S59_Y0.6410.96
53_N58_Q0.6410.96
68_M183_A0.6410.96
101_N105_E0.6380.96
17_F111_F0.6350.96
93_G145_L0.6320.96
156_Q164_E0.6270.96
144_A147_T0.6240.96
189_F192_A0.6230.96
167_I172_T0.6200.96
100_Y137_D0.6180.96
98_K157_A0.6170.95
85_P114_F0.6170.95
7_V23_F0.6090.95
156_Q159_K0.6050.95
11_Y15_F0.6040.95
92_E151_Q0.6020.95
37_M98_K0.6020.95
68_M72_L0.5990.95
150_Y153_V0.5990.95
108_T112_Q0.5960.95
23_F27_I0.5940.94
22_A25_E0.5920.94
26_A190_E0.5890.94
40_E43_P0.5860.94
100_Y144_A0.5790.94
185_G188_V0.5780.94
114_F121_I0.5780.94
79_P82_S0.5770.94
92_E154_Q0.5760.94
102_K134_V0.5740.93
105_E134_V0.5730.93
48_Q52_V0.5710.93
5_I175_I0.5700.93
130_L133_E0.5680.93
49_L52_V0.5680.93
94_F110_V0.5630.93
12_V81_V0.5620.93
88_D154_Q0.5600.93
157_A160_H0.5550.92
9_S16_C0.5540.92
165_A177_D0.5510.92
45_P48_Q0.5510.92
11_Y121_I0.5510.92
95_H153_V0.5490.92
32_V193_I0.5490.92
90_A122_G0.5470.92
68_M71_K0.5460.92
45_P50_D0.5450.92
64_S185_G0.5450.92
53_N61_W0.5430.91
79_P118_D0.5390.91
22_A183_A0.5360.91
8_Y39_F0.5340.91
58_Q61_W0.5340.91
92_E149_T0.5300.90
87_T114_F0.5260.90
153_V157_A0.5250.90
6_K165_A0.5250.90
128_T131_A0.5230.90
99_E149_T0.5160.89
90_A127_L0.5150.89
95_H99_E0.5150.89
5_I173_F0.5140.89
126_I130_L0.5140.89
81_V85_P0.5130.89
21_A112_Q0.5070.88
119_Q130_L0.5070.88
29_G186_K0.5050.88
85_P120_N0.5050.88
119_Q133_E0.5040.88
87_T121_I0.5030.88
8_Y160_H0.5030.88
17_F21_A0.5010.88
67_P71_K0.5000.88
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2imfA 2 0.97 100 0.255 Contact Map
3fz5A 2 0.93 100 0.262 Contact Map
1r4wA 2 0.99 100 0.263 Contact Map
3rppA 2 0.98 100 0.265 Contact Map
3gl5A 2 0.985 100 0.287 Contact Map
3kzqA 3 0.97 100 0.301 Contact Map
2in3A 1 0.945 100 0.339 Contact Map
4nxiA 2 0.86 100 0.456 Contact Map
3f4sA 1 0.785 99.9 0.488 Contact Map
3c7mA 1 0.855 99.9 0.492 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0194 seconds.