EFEU - BACSU - GREMLIN Contacts

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EFEU - Ferrous iron permease EfeU

UniProt:	P39595	Sequences: MARGLALILFSLLMVFGSAAHAEDDPIAALIQLNKQMIKSVKDGDMDSAQQTFDTFKAKWKKEEPSIKKENLSSHSEMDANIAMISLSFINQDARKLKTQLEELASHLETYQQAVVLKKTSSGQSRASLTAYIQSLKDTKQFIEKKQLDEASSAIDNLVTSWLAVEGDVVSQSKEAYTTSEENLALMKAEIGSHPEKVSKQIDEMIQLLEPIASSSYSWWDAALIPVREGMEALLVIGALLTMTKKARVTRSSTWIWGGASAGMAVSLAAGIGVTVLFSSSVFGENNFLLGGVTGVLSAVMLLYVGVWLHRNASMDKWREKINIQKSQALKKRSLLSFALIAFLAVVREGLETVIFFIGLVGKLPLTELIGGTAAGLIVLVIVGVLMIKLGMRIPLKPFFLLSMAVVLYMCVKFLGTGVHSLQLAGILPSDAESWLPSVSVLGIYPSVYSTIPQMLILLFLLIALVSEAAKHFTNGKELTK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	481 (385)
Sequences:	413 (315)
Seq/√Len:	16.0

BACSU - EFEU

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
147_Q	150_E	7.124	1.00
436_L	444_I	4.309	1.00
270_A	347_V	3.518	0.99
265_A	462_L	3.215	0.99
265_A	382_I	3.166	0.99
273_G	374_A	3.090	0.99
288_F	291_G	2.994	0.98
273_G	277_L	2.910	0.98
278_F	347_V	2.910	0.98
265_A	269_A	2.900	0.98
287_N	306_G	2.847	0.98
431_D	449_Y	2.728	0.97
271_G	351_L	2.625	0.96
444_I	451_T	2.618	0.96
180_S	212_I	2.567	0.95
144_E	199_S	2.548	0.95
448_V	452_I	2.463	0.94
423_Q	447_S	2.402	0.94
137_K	206_I	2.399	0.93
309_L	321_K	2.335	0.92
306_G	310_H	2.288	0.92
264_M	338_F	2.158	0.89
437_P	446_P	2.152	0.89
373_T	376_G	2.151	0.89
267_S	350_G	2.085	0.87
294_T	376_G	2.076	0.87
111_Y	114_A	2.064	0.87
256_I	301_M	2.040	0.86
176_A	306_G	1.963	0.84
272_I	459_L	1.954	0.84
302_L	418_G	1.936	0.83
231_M	235_L	1.933	0.83
329_A	437_P	1.913	0.82
378_I	382_I	1.909	0.82
105_A	108_L	1.907	0.82
338_F	404_M	1.882	0.81
169_V	212_I	1.879	0.81
176_A	287_N	1.874	0.81
448_V	455_M	1.864	0.80
363_K	450_S	1.852	0.80
433_E	436_L	1.832	0.79
363_K	394_I	1.810	0.78
170_V	177_Y	1.803	0.78
148_L	393_R	1.801	0.78
175_E	179_T	1.796	0.78
258_G	456_L	1.791	0.78
173_S	176_A	1.784	0.77
248_R	296_V	1.774	0.77
256_I	273_G	1.772	0.77
265_A	393_R	1.767	0.77
289_L	293_V	1.758	0.76
155_I	245_K	1.752	0.76
132_Y	158_L	1.751	0.76
236_V	239_A	1.742	0.76
267_S	271_G	1.715	0.74
377_L	381_V	1.704	0.74
304_Y	311_R	1.696	0.74
218_S	369_L	1.672	0.73
262_A	381_V	1.648	0.71
447_S	450_S	1.639	0.71
159_V	287_N	1.639	0.71
313_A	404_M	1.617	0.70
198_V	211_P	1.604	0.69
155_I	414_F	1.584	0.68
159_V	306_G	1.572	0.68
274_V	283_F	1.568	0.67
138_D	471_K	1.568	0.67
145_K	374_A	1.539	0.66
124_Q	300_V	1.524	0.65
241_L	253_S	1.520	0.65
272_I	428_L	1.518	0.65
301_M	305_V	1.514	0.65
156_D	160_T	1.508	0.64
354_V	407_V	1.502	0.64
162_W	221_D	1.498	0.64
87_L	91_N	1.485	0.63
216_S	379_V	1.485	0.63
226_P	357_F	1.482	0.63
141_Q	447_S	1.445	0.61
302_L	403_S	1.435	0.60
304_Y	358_I	1.433	0.60
234_L	387_M	1.432	0.60
244_T	341_I	1.423	0.60
217_Y	373_T	1.422	0.60
252_S	335_L	1.407	0.59
312_N	317_K	1.406	0.59
248_R	440_S	1.399	0.58
162_W	177_Y	1.399	0.58
227_V	335_L	1.392	0.58
433_E	455_M	1.381	0.57
273_G	452_I	1.371	0.57
239_A	330_L	1.364	0.56
220_W	355_I	1.357	0.56
307_V	358_I	1.353	0.56
163_L	302_L	1.330	0.54
387_M	394_I	1.327	0.54
287_N	310_H	1.326	0.54
221_D	295_G	1.325	0.54
399_F	425_A	1.322	0.54
264_M	312_N	1.321	0.54
291_G	443_G	1.318	0.54
304_Y	418_G	1.318	0.54
89_F	322_I	1.291	0.52
361_V	369_L	1.291	0.52
163_L	418_G	1.289	0.52
177_Y	295_G	1.288	0.52
238_G	384_G	1.285	0.52
220_W	370_I	1.282	0.52
438_S	444_I	1.282	0.52
196_E	452_I	1.278	0.51
177_Y	217_Y	1.272	0.51
304_Y	408_L	1.271	0.51
430_S	447_S	1.267	0.51
286_N	336_L	1.264	0.51
159_V	163_L	1.263	0.51
138_D	374_A	1.260	0.50
203_D	265_A	1.254	0.50
167_G	177_Y	1.251	0.50
223_A	458_L	1.249	0.50
322_I	363_K	1.247	0.50
287_N	291_G	1.245	0.49
199_S	382_I	1.240	0.49
131_A	271_G	1.239	0.49
251_R	265_A	1.231	0.49
202_I	322_I	1.220	0.48
367_T	378_I	1.219	0.48
158_L	163_L	1.217	0.48
244_T	256_I	1.215	0.48
306_G	461_L	1.214	0.48
271_G	274_V	1.200	0.47
257_W	260_A	1.198	0.47
110_T	115_V	1.196	0.47
132_Y	403_S	1.196	0.47
414_F	418_G	1.191	0.46
236_V	425_A	1.186	0.46
137_K	199_S	1.184	0.46
257_W	384_G	1.173	0.45
220_W	223_A	1.171	0.45
136_L	202_I	1.152	0.44
207_Q	458_L	1.151	0.44
150_E	153_S	1.150	0.44
172_Q	339_A	1.149	0.44
382_I	471_K	1.147	0.44
100_Q	107_H	1.141	0.43
184_L	310_H	1.141	0.43
354_V	376_G	1.139	0.43
321_K	399_F	1.138	0.43
354_V	360_L	1.136	0.43
117_L	386_L	1.131	0.43
100_Q	290_L	1.125	0.43
303_L	461_L	1.124	0.43
367_T	444_I	1.121	0.42
322_I	457_I	1.102	0.41
184_L	403_S	1.101	0.41
226_P	292_G	1.100	0.41
299_A	415_L	1.097	0.41
289_L	427_I	1.096	0.41
425_A	428_L	1.096	0.41
149_D	324_I	1.095	0.41
155_I	463_I	1.093	0.41
238_G	387_M	1.085	0.40
223_A	379_V	1.084	0.40
359_G	364_L	1.080	0.40
433_E	451_T	1.074	0.40
187_M	198_V	1.071	0.40
152_S	192_G	1.070	0.39
341_I	384_G	1.069	0.39
345_A	354_V	1.069	0.39
180_S	231_M	1.068	0.39
256_I	361_V	1.068	0.39
104_L	165_V	1.068	0.39
441_V	460_F	1.067	0.39
132_Y	170_V	1.067	0.39
208_L	290_L	1.066	0.39
427_I	462_L	1.065	0.39
288_F	351_L	1.065	0.39
173_S	212_I	1.064	0.39
371_G	459_L	1.058	0.39
155_I	345_A	1.051	0.38
250_T	320_E	1.051	0.38
174_K	236_V	1.046	0.38
159_V	288_F	1.045	0.38
339_A	342_A	1.044	0.38
294_T	311_R	1.035	0.38
434_S	446_P	1.028	0.37
176_A	212_I	1.026	0.37
292_G	342_A	1.025	0.37
394_I	438_S	1.016	0.37
179_T	198_V	1.016	0.37
268_L	340_L	1.013	0.36
124_Q	428_L	1.012	0.36
147_Q	265_A	1.011	0.36
334_S	406_V	1.008	0.36
139_T	187_M	1.006	0.36
169_V	351_L	1.003	0.36
106_S	141_Q	0.995	0.35
205_M	409_Y	0.994	0.35
134_Q	459_L	0.991	0.35
219_W	346_V	0.987	0.35
129_L	363_K	0.986	0.35
367_T	374_A	0.985	0.35
341_I	355_I	0.981	0.35
224_L	301_M	0.981	0.35
417_T	443_G	0.980	0.35
185_A	407_V	0.977	0.34
218_S	364_L	0.975	0.34
209_L	402_L	0.974	0.34
252_S	369_L	0.970	0.34
260_A	267_S	0.970	0.34
370_I	378_I	0.968	0.34
113_Q	160_T	0.968	0.34
204_E	466_V	0.966	0.34
139_T	227_V	0.962	0.34
403_S	418_G	0.961	0.34
242_T	246_K	0.957	0.33
163_L	263_G	0.954	0.33
224_L	338_F	0.952	0.33
318_W	321_K	0.951	0.33
134_Q	382_I	0.950	0.33
223_A	375_A	0.950	0.33
378_I	436_L	0.943	0.33
288_F	443_G	0.943	0.33
310_H	384_G	0.941	0.33
271_G	350_G	0.940	0.33
111_Y	347_V	0.935	0.32
255_W	410_M	0.935	0.32
419_V	467_S	0.935	0.32
321_K	393_R	0.932	0.32
149_D	434_S	0.927	0.32
312_N	357_F	0.925	0.32
411_C	450_S	0.924	0.32
345_A	376_G	0.924	0.32
404_M	418_G	0.923	0.32
130_T	203_D	0.918	0.31
144_E	385_V	0.915	0.31
257_W	346_V	0.915	0.31
197_K	378_I	0.914	0.31
300_V	374_A	0.912	0.31
359_G	413_K	0.910	0.31
439_V	442_L	0.910	0.31
159_V	188_K	0.909	0.31
142_F	147_Q	0.905	0.31
277_L	386_L	0.904	0.31
233_A	292_G	0.901	0.31
148_L	194_H	0.900	0.31
287_N	326_K	0.898	0.30
154_A	231_M	0.898	0.30
240_L	424_L	0.897	0.30
217_Y	376_G	0.896	0.30
91_N	110_T	0.892	0.30
97_L	355_I	0.890	0.30
291_G	351_L	0.888	0.30
103_E	107_H	0.888	0.30
270_A	285_E	0.884	0.30
158_L	263_G	0.882	0.30
254_T	381_V	0.879	0.29
345_A	447_S	0.878	0.29
398_P	414_F	0.878	0.29
301_M	341_I	0.877	0.29
455_M	458_L	0.877	0.29
158_L	188_K	0.876	0.29
100_Q	105_A	0.876	0.29
256_I	376_G	0.874	0.29
205_M	236_V	0.874	0.29
312_N	406_V	0.872	0.29
129_L	212_I	0.872	0.29
303_L	460_F	0.870	0.29
207_Q	261_S	0.866	0.29
347_V	359_G	0.866	0.29
162_W	420_H	0.865	0.29
239_A	394_I	0.864	0.29
99_T	269_A	0.861	0.29
370_I	374_A	0.856	0.28
253_S	283_F	0.855	0.28
338_F	449_Y	0.854	0.28
321_K	410_M	0.853	0.28
322_I	393_R	0.852	0.28
159_V	291_G	0.852	0.28
296_V	458_L	0.849	0.28
437_P	445_Y	0.845	0.28
163_L	291_G	0.840	0.28
354_V	373_T	0.840	0.28
96_K	460_F	0.836	0.27
174_K	415_L	0.836	0.27
307_V	406_V	0.833	0.27
142_F	150_E	0.828	0.27
150_E	261_S	0.825	0.27
237_I	264_M	0.823	0.27
252_S	410_M	0.816	0.27
426_G	442_L	0.816	0.27
256_I	432_A	0.815	0.27
118_K	267_S	0.815	0.27
124_Q	146_K	0.813	0.26
345_A	373_T	0.812	0.26
145_K	200_K	0.811	0.26
367_T	393_R	0.811	0.26
222_A	420_H	0.810	0.26
278_F	393_R	0.809	0.26
297_L	444_I	0.809	0.26
286_N	301_M	0.808	0.26
150_E	452_I	0.808	0.26
266_V	341_I	0.806	0.26
129_L	165_V	0.806	0.26
279_S	337_S	0.804	0.26
95_R	459_L	0.804	0.26
247_A	444_I	0.801	0.26
138_D	154_A	0.801	0.26
200_K	204_E	0.800	0.26
427_I	436_L	0.799	0.26
136_L	284_G	0.799	0.26
160_T	353_T	0.798	0.26
132_Y	169_V	0.798	0.26
305_V	415_L	0.798	0.26
170_V	236_V	0.796	0.26
332_K	441_V	0.795	0.26
342_A	347_V	0.795	0.26
297_L	319_R	0.789	0.25
350_G	414_F	0.789	0.25
398_P	401_L	0.788	0.25
234_L	237_I	0.788	0.25
216_S	240_L	0.787	0.25
95_R	367_T	0.785	0.25
358_I	407_V	0.785	0.25
296_V	379_V	0.782	0.25
226_P	410_M	0.782	0.25
222_A	369_L	0.782	0.25
132_Y	184_L	0.778	0.25
269_A	382_I	0.777	0.25
96_K	145_K	0.776	0.25
300_V	382_I	0.776	0.25
407_V	415_L	0.775	0.25
137_K	459_L	0.774	0.25
158_L	271_G	0.773	0.25
106_S	452_I	0.772	0.25
261_S	325_Q	0.772	0.25
258_G	300_V	0.772	0.25
147_Q	374_A	0.768	0.24
136_L	231_M	0.767	0.24
318_W	380_L	0.766	0.24
257_W	267_S	0.762	0.24
93_D	96_K	0.761	0.24
325_Q	383_V	0.759	0.24
89_F	344_L	0.759	0.24
207_Q	374_A	0.759	0.24
315_M	319_R	0.755	0.24
177_Y	221_D	0.755	0.24
335_L	339_A	0.755	0.24
219_W	241_L	0.754	0.24
177_Y	310_H	0.752	0.24
144_E	428_L	0.751	0.24
178_T	405_A	0.751	0.24
100_Q	104_L	0.751	0.24
136_L	423_Q	0.749	0.24
287_N	307_V	0.749	0.24
163_L	413_K	0.748	0.24
459_L	463_I	0.748	0.24
383_V	436_L	0.747	0.24
226_P	244_T	0.746	0.23
429_P	439_V	0.745	0.23
274_V	351_L	0.744	0.23
413_K	424_L	0.736	0.23
322_I	369_L	0.735	0.23
212_I	287_N	0.734	0.23
222_A	226_P	0.733	0.23
219_W	305_V	0.732	0.23
252_S	260_A	0.730	0.23
209_L	394_I	0.730	0.23
263_G	319_R	0.729	0.23
319_R	355_I	0.729	0.23
295_G	421_S	0.729	0.23
282_V	389_K	0.727	0.23
263_G	369_L	0.726	0.23
211_P	451_T	0.725	0.23
293_V	462_L	0.724	0.23
249_V	252_S	0.723	0.23
174_K	265_A	0.722	0.23
294_T	414_F	0.722	0.23
182_E	286_N	0.722	0.23
225_I	410_M	0.721	0.22
263_G	267_S	0.719	0.22
312_N	408_L	0.716	0.22
130_T	474_T	0.714	0.22
163_L	170_V	0.713	0.22
137_K	428_L	0.712	0.22
140_K	144_E	0.712	0.22
209_L	333_R	0.711	0.22
163_L	351_L	0.711	0.22
371_G	393_R	0.705	0.22
149_D	261_S	0.704	0.22
391_G	399_F	0.701	0.22
419_V	437_P	0.701	0.22
263_G	364_L	0.700	0.22
309_L	344_L	0.700	0.22
191_I	363_K	0.697	0.22
231_M	388_I	0.697	0.22
163_L	287_N	0.695	0.21
164_A	383_V	0.695	0.21
170_V	287_N	0.693	0.21
153_S	207_Q	0.692	0.21
163_L	403_S	0.691	0.21
193_S	197_K	0.689	0.21
382_I	466_V	0.687	0.21
255_W	336_L	0.686	0.21
134_Q	197_K	0.684	0.21
342_A	458_L	0.681	0.21
380_L	399_F	0.677	0.21
162_W	315_M	0.676	0.21
104_L	114_A	0.675	0.21
141_Q	175_E	0.674	0.21
158_L	260_A	0.673	0.21
395_P	399_F	0.672	0.21
258_G	262_A	0.671	0.21
141_Q	377_L	0.671	0.21
130_T	277_L	0.669	0.20
258_G	387_M	0.669	0.20
165_V	180_S	0.668	0.20
285_E	433_E	0.665	0.20
293_V	358_I	0.665	0.20
147_Q	455_M	0.664	0.20
379_V	467_S	0.661	0.20
161_S	260_A	0.661	0.20
139_T	370_I	0.661	0.20
148_L	265_A	0.659	0.20
160_T	163_L	0.658	0.20
382_I	472_H	0.657	0.20
360_L	453_P	0.657	0.20
227_V	410_M	0.656	0.20
289_L	425_A	0.655	0.20
335_L	357_F	0.654	0.20
97_L	360_L	0.654	0.20
290_L	359_G	0.654	0.20
243_M	399_F	0.653	0.20
289_L	342_A	0.652	0.20
245_K	392_M	0.650	0.20
404_M	408_L	0.648	0.20
202_I	320_E	0.646	0.20
337_S	342_A	0.643	0.19
348_R	356_F	0.643	0.19
166_E	356_F	0.643	0.19
166_E	228_R	0.643	0.19
166_E	348_R	0.643	0.19
228_R	348_R	0.643	0.19
228_R	356_F	0.643	0.19
345_A	461_L	0.642	0.19
310_H	423_Q	0.641	0.19
157_N	347_V	0.641	0.19
311_R	317_K	0.637	0.19
277_L	427_I	0.634	0.19
267_S	351_L	0.634	0.19
287_N	351_L	0.633	0.19
238_G	242_T	0.630	0.19
129_L	169_V	0.629	0.19
252_S	406_V	0.627	0.19
158_L	389_K	0.627	0.19
129_L	132_Y	0.627	0.19
379_V	449_Y	0.626	0.19
259_G	423_Q	0.622	0.19
369_L	373_T	0.621	0.19
287_N	357_F	0.621	0.19
215_S	383_V	0.620	0.19
463_I	467_S	0.620	0.19
244_T	422_L	0.619	0.19
303_L	316_D	0.619	0.19
217_Y	221_D	0.619	0.19
248_R	273_G	0.618	0.19
163_L	288_F	0.617	0.19
131_A	135_S	0.617	0.19
312_N	353_T	0.614	0.18
275_T	290_L	0.613	0.18
155_I	295_G	0.612	0.18
264_M	394_I	0.612	0.18
162_W	223_A	0.611	0.18
134_Q	196_E	0.610	0.18
313_A	460_F	0.610	0.18
429_P	467_S	0.610	0.18
144_E	474_T	0.608	0.18
274_V	299_A	0.607	0.18
240_L	304_Y	0.606	0.18
306_G	407_V	0.605	0.18
385_V	405_A	0.603	0.18
99_T	386_L	0.603	0.18
221_D	263_G	0.602	0.18
104_L	413_K	0.600	0.18
226_P	376_G	0.599	0.18
95_R	203_D	0.598	0.18
185_A	307_V	0.597	0.18
382_I	439_V	0.594	0.18
369_L	377_L	0.592	0.18
272_I	324_I	0.592	0.18
265_A	324_I	0.592	0.18
246_K	399_F	0.592	0.18
324_I	409_Y	0.589	0.18
159_V	418_G	0.586	0.17
162_W	167_G	0.586	0.17
146_K	241_L	0.585	0.17
376_G	461_L	0.584	0.17
246_K	405_A	0.581	0.17
341_I	410_M	0.580	0.17
267_S	274_V	0.576	0.17
286_N	360_L	0.576	0.17
101_L	109_E	0.574	0.17
95_R	328_Q	0.574	0.17
347_V	351_L	0.574	0.17
275_T	387_M	0.572	0.17
172_Q	322_I	0.571	0.17
240_L	345_A	0.570	0.17
225_I	353_T	0.570	0.17
386_L	419_V	0.569	0.17
256_I	297_L	0.568	0.17
269_A	273_G	0.566	0.17
311_R	314_S	0.564	0.17
100_Q	458_L	0.564	0.17
195_P	300_V	0.564	0.17
91_N	191_I	0.559	0.17
303_L	411_C	0.558	0.17
97_L	272_I	0.558	0.17
458_L	473_F	0.558	0.17
190_E	195_P	0.557	0.17
128_S	295_G	0.557	0.17
103_E	439_V	0.557	0.17
311_R	392_M	0.556	0.16
300_V	325_Q	0.555	0.16
162_W	413_K	0.555	0.16
311_R	373_T	0.555	0.16
278_F	467_S	0.554	0.16
428_L	436_L	0.553	0.16
116_V	451_T	0.553	0.16
145_K	472_H	0.553	0.16
168_D	415_L	0.552	0.16
234_L	414_F	0.552	0.16
212_I	330_L	0.552	0.16
170_V	407_V	0.551	0.16
254_T	386_L	0.545	0.16
217_Y	263_G	0.543	0.16
279_S	388_I	0.543	0.16
162_W	310_H	0.542	0.16
423_Q	426_G	0.542	0.16
177_Y	236_V	0.540	0.16
292_G	399_F	0.539	0.16
236_V	368_E	0.539	0.16
409_Y	450_S	0.539	0.16
268_L	459_L	0.538	0.16
180_S	288_F	0.538	0.16
367_T	389_K	0.537	0.16
142_F	396_L	0.536	0.16
261_S	382_I	0.532	0.16
200_K	434_S	0.532	0.16
106_S	110_T	0.532	0.16
388_I	418_G	0.529	0.16
164_A	414_F	0.528	0.16
256_I	279_S	0.528	0.16
450_S	453_P	0.528	0.16
334_S	407_V	0.523	0.15
191_I	240_L	0.522	0.15
144_E	382_I	0.522	0.15
206_I	430_S	0.522	0.15
169_V	271_G	0.522	0.15
107_H	273_G	0.521	0.15
137_K	210_E	0.521	0.15
239_A	289_L	0.519	0.15
226_P	380_L	0.518	0.15
104_L	358_I	0.518	0.15
172_Q	411_C	0.517	0.15
321_K	380_L	0.516	0.15
362_G	404_M	0.516	0.15
309_L	409_Y	0.516	0.15
100_Q	338_F	0.515	0.15
120_T	439_V	0.513	0.15
99_T	374_A	0.513	0.15
93_D	462_L	0.513	0.15
295_G	364_L	0.512	0.15
124_Q	175_E	0.508	0.15
161_S	188_K	0.508	0.15
248_R	374_A	0.507	0.15
270_A	355_I	0.504	0.15
159_V	351_L	0.504	0.15
413_K	428_L	0.502	0.15
93_D	107_H	0.500	0.15

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1yviA	1	0.2827	76.8	0.972	Contact Map
4uxvA	1	0.3472	76.4	0.972	Contact Map
4pacA	1	0.3077	76	0.972	Contact Map
2lemA	1	0.4137	74.6	0.972	Contact Map
4jkvA	2	0.6861	73.9	0.972	Contact Map
4g78A	1	0.2765	63.1	0.974	Contact Map
3r2pA	2	0.3638	60.4	0.975	Contact Map
3us6A	1	0.2786	56.1	0.975	Contact Map
3myfA	3	0.2412	55.1	0.975	Contact Map
4bgoA	1	0.4366	52.9	0.976	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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