DLTA - BACSU - GREMLIN Contacts

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DLTA - D-alanine--poly(phosphoribitol) ligase subunit 1

UniProt:	P39581	Sequences: MKLLHAIQTHAETYPQTDAFRSQGQSLTYQELWEQSDRAAAAIQKRISGEKKSPILVYGHMEPHMIVSFLGSVKAGHPYIPVDLSIPSERIAKIIESSGAELLIHAAGLSIDAVGQQIQTVSAEELLENEGGSVSQDQWVKEHETFYIIYTSGSTGNPKGVQISAANLQSFTDWICADFPVSGGKIFLNQAPFSFDLSVMDLYPCLQSGGTLHCVTKDAVNKPKVLFEELKKSGLNVWTSTPSFVQMCLMDPGFSQDLLPHADTFMFCGEVLPVSVAKALLERFPKAKIFNTYGPTEATVAVTSVEITNDVISRSESLPVGFAKPDMNIFIMDEEGQPLPEGEKGEIVIAGPSVSRGYLGEPELTEKAFFSHEGQWAYRTGDAGFIQDGQIFCQGRLDFQIKLHGYRMELEEIEFHVRQSQYVRSAVVIPYQPNGTVEYLIAAIVPEEHEFEKEFQLTSAIKKELAASLPAYMIPRKFIYQDHIQMTANGKIDRKRIGEEVLV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	503 (477)
Sequences:	71669 (52020)
Seq/√Len:	2381.8

ECOLI - ENTF AAS ACSA PRPE LCFA CAIC FADK ENTE MENE PAAK
BACSU - DLTA SRFAC PPSE LCFB LCFA ACSA PPSB PPSC YNGI YDAB DHBE MENE YHFT YTCI DHBF PKSJ PPSA SRFAB PKSN SRFAA PPSD
HALSA - Q9HRY8 Q9HQU8 Q9HSM3 Q9HQ43 Q9HQN8 Q9HNK0
SULSO - Q97YK9 Q97UX8 Q97U22 Q97VT6 Q97UW7 Q97WQ0 Q97WQ9 Q97VU7 Q97XW4 Q97UF6 Q97WK0 Q97V27 Q97WS5 Q980E4 Q97X52 Q97XW5 Q97VJ6 Q97WU3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
145_T	162_Q	3.884	1.00
420_S	464_E	3.211	1.00
347_I	384_G	3.132	1.00
37_D	74_K	2.954	1.00
328_N	350_A	2.916	1.00
361_E	364_L	2.872	1.00
56_L	100_A	2.818	1.00
97_S	150_Y	2.807	1.00
164_S	356_R	2.769	1.00
33_W	74_K	2.769	1.00
53_S	101_E	2.748	1.00
21_R	211_T	2.644	1.00
48_S	77_H	2.546	1.00
346_E	379_R	2.535	1.00
402_K	407_R	2.480	1.00
186_I	211_T	2.464	1.00
425_S	486_M	2.386	1.00
18_D	26_S	2.376	1.00
42_A	46_R	2.371	1.00
99_G	360_G	2.359	1.00
330_F	338_P	2.344	1.00
14_Y	17_T	2.316	1.00
418_R	426_A	2.296	1.00
54_P	80_I	2.290	1.00
8_Q	33_W	2.280	1.00
332_M	348_V	2.272	1.00
35_Q	67_V	2.217	1.00
10_H	14_Y	2.190	1.00
344_K	383_A	2.185	1.00
417_V	442_A	2.184	1.00
93_K	157_N	2.164	1.00
348_V	379_R	2.162	1.00
97_S	361_E	2.136	1.00
33_W	37_D	2.131	1.00
333_D	337_Q	2.129	1.00
68_S	104_I	2.111	1.00
493_D	496_R	2.091	1.00
399_F	494_R	2.089	1.00
386_I	392_F	2.085	1.00
441_I	479_I	2.068	1.00
72_S	77_H	2.060	1.00
419_Q	468_S	2.045	1.00
228_E	232_K	2.024	1.00
364_L	367_K	2.005	1.00
319_P	392_F	1.996	1.00
185_K	263_D	1.979	1.00
141_K	144_E	1.963	1.00
386_I	390_Q	1.916	1.00
274_V	278_K	1.909	1.00
21_R	26_S	1.908	1.00
185_K	236_N	1.889	1.00
362_P	366_E	1.882	1.00
92_A	96_E	1.875	1.00
39_A	67_V	1.870	1.00
330_F	348_V	1.866	1.00
51_K	144_E	1.821	1.00
16_Q	30_Q	1.810	1.00
412_E	473_M	1.805	1.00
44_Q	75_A	1.776	1.00
52_K	144_E	1.769	1.00
21_R	233_S	1.749	1.00
234_G	261_H	1.743	1.00
36_S	74_K	1.719	1.00
424_R	447_E	1.713	1.00
403_L	408_M	1.705	1.00
344_K	394_Q	1.698	1.00
418_R	425_S	1.694	1.00
496_R	499_E	1.691	1.00
414_E	428_V	1.674	1.00
30_Q	34_E	1.673	1.00
9_T	13_T	1.672	1.00
429_I	443_A	1.665	1.00
66_I	202_L	1.660	1.00
213_H	235_L	1.649	1.00
164_S	167_N	1.637	1.00
28_T	31_E	1.631	1.00
385_F	391_I	1.626	1.00
60_H	106_A	1.619	1.00
341_E	385_F	1.591	1.00
56_L	82_V	1.574	1.00
54_P	78_P	1.568	1.00
73_V	146_F	1.552	1.00
145_T	356_R	1.552	1.00
416_H	468_S	1.548	1.00
445_V	484_I	1.548	1.00
122_S	125_E	1.547	1.00
150_Y	160_G	1.546	1.00
443_A	497_I	1.546	1.00
10_H	13_T	1.533	1.00
444_I	480_Y	1.528	1.00
15_P	30_Q	1.528	1.00
240_S	245_V	1.528	1.00
422_Y	460_A	1.525	1.00
27_L	67_V	1.525	1.00
288_K	306_E	1.519	1.00
176_C	208_S	1.518	1.00
302_V	349_I	1.512	1.00
363_E	367_K	1.511	1.00
464_E	468_S	1.507	1.00
428_V	442_A	1.501	1.00
225_V	228_E	1.498	1.00
331_I	384_G	1.491	1.00
8_Q	74_K	1.487	1.00
205_C	210_G	1.483	1.00
11_A	33_W	1.472	1.00
55_I	72_S	1.472	1.00
18_D	21_R	1.456	1.00
177_A	325_P	1.456	1.00
231_K	257_D	1.454	1.00
432_Q	438_E	1.450	1.00
316_E	388_D	1.449	1.00
37_D	41_A	1.443	1.00
18_D	211_T	1.438	1.00
17_T	184_G	1.437	1.00
143_H	166_A	1.430	1.00
162_Q	359_L	1.429	1.00
148_I	359_L	1.426	1.00
340_P	343_E	1.423	1.00
462_K	478_F	1.422	1.00
384_G	393_C	1.415	1.00
295_P	378_Y	1.413	1.00
245_V	265_F	1.413	1.00
459_S	463_K	1.400	1.00
98_S	150_Y	1.399	1.00
188_L	235_L	1.394	1.00
487_T	493_D	1.394	1.00
162_Q	357_G	1.393	1.00
27_L	63_P	1.382	1.00
383_A	397_L	1.379	1.00
243_S	270_E	1.378	1.00
443_A	498_G	1.375	1.00
446_P	480_Y	1.374	1.00
95_I	100_A	1.369	1.00
278_K	282_E	1.369	1.00
22_S	63_P	1.368	1.00
186_I	213_H	1.367	1.00
316_E	390_Q	1.359	1.00
333_D	339_L	1.357	1.00
167_N	299_T	1.355	1.00
422_Y	450_E	1.354	1.00
303_T	329_I	1.353	1.00
443_A	481_Q	1.348	1.00
56_L	95_I	1.347	1.00
80_I	98_S	1.347	1.00
222_K	225_V	1.346	1.00
370_F	379_R	1.341	1.00
355_S	369_F	1.334	1.00
142_E	166_A	1.331	1.00
229_E	233_S	1.331	1.00
42_A	126_L	1.330	1.00
334_E	397_L	1.329	1.00
322_F	390_Q	1.327	1.00
55_I	77_H	1.327	1.00
444_I	478_F	1.326	1.00
433_P	439_Y	1.324	1.00
185_K	237_V	1.316	1.00
182_S	185_K	1.315	1.00
466_A	474_I	1.312	1.00
329_I	349_I	1.305	1.00
19_A	32_L	1.303	1.00
215_V	229_E	1.303	1.00
350_A	377_A	1.299	1.00
52_K	356_R	1.298	1.00
441_I	477_K	1.290	1.00
425_S	445_V	1.289	1.00
54_P	148_I	1.289	1.00
166_A	352_P	1.285	1.00
368_A	378_Y	1.285	1.00
463_K	467_A	1.284	1.00
457_L	460_A	1.279	1.00
97_S	360_G	1.269	1.00
452_E	457_L	1.269	1.00
401_I	410_L	1.263	1.00
70_L	206_L	1.257	1.00
39_A	71_G	1.253	1.00
323_A	329_I	1.247	1.00
330_F	377_A	1.245	1.00
93_K	97_S	1.243	1.00
431_Y	441_I	1.231	1.00
97_S	157_N	1.231	1.00
267_F	272_L	1.231	1.00
430_P	438_E	1.230	1.00
35_Q	38_R	1.228	1.00
162_Q	356_R	1.227	1.00
54_P	359_L	1.224	1.00
238_W	262_A	1.210	1.00
346_E	397_L	1.209	1.00
78_P	145_T	1.208	1.00
466_A	471_A	1.207	1.00
186_I	235_L	1.206	1.00
411_E	415_F	1.205	1.00
462_K	466_A	1.201	1.00
399_F	411_E	1.192	1.00
197_L	239_T	1.187	1.00
88_S	92_A	1.186	1.00
57_V	68_S	1.186	1.00
148_I	160_G	1.182	1.00
305_V	390_Q	1.167	1.00
48_S	53_S	1.159	1.00
406_Y	472_Y	1.159	1.00
439_Y	476_R	1.158	1.00
464_E	467_A	1.157	1.00
280_L	284_F	1.152	1.00
458_T	480_Y	1.148	1.00
58_Y	91_I	1.139	1.00
439_Y	477_K	1.139	1.00
140_V	144_E	1.136	1.00
33_W	135_S	1.135	1.00
34_E	38_R	1.131	1.00
246_Q	276_V	1.130	1.00
32_L	70_L	1.130	1.00
25_Q	63_P	1.129	1.00
347_I	393_C	1.128	1.00
237_V	264_T	1.124	1.00
19_A	29_Y	1.121	1.00
8_Q	37_D	1.110	1.00
250_M	279_A	1.106	1.00
26_S	233_S	1.104	1.00
163_I	167_N	1.103	1.00
48_S	55_I	1.102	1.00
27_L	35_Q	1.101	1.00
230_L	261_H	1.096	1.00
224_K	251_D	1.093	1.00
143_H	164_S	1.093	1.00
35_Q	64_H	1.091	1.00
339_L	343_E	1.090	1.00
71_G	75_A	1.089	1.00
65_M	193_F	1.084	1.00
151_T	161_V	1.084	1.00
96_E	157_N	1.079	1.00
465_L	474_I	1.069	1.00
42_A	45_K	1.066	1.00
40_A	74_K	1.065	1.00
21_R	213_H	1.064	1.00
22_S	25_Q	1.064	1.00
458_T	462_K	1.063	1.00
364_L	368_A	1.063	1.00
273_P	276_V	1.059	1.00
442_A	478_F	1.058	1.00
31_E	34_E	1.058	1.00
213_H	233_S	1.053	1.00
32_L	67_V	1.050	1.00
400_Q	409_E	1.047	1.00
416_H	419_Q	1.047	1.00
191_A	197_L	1.045	1.00
424_R	445_V	1.044	1.00
431_Y	477_K	1.040	1.00
186_I	236_N	1.039	1.00
470_P	473_M	1.035	1.00
481_Q	484_I	1.034	1.00
458_T	478_F	1.034	1.00
320_V	393_C	1.032	1.00
348_V	377_A	1.031	1.00
327_M	353_S	1.029	1.00
279_A	283_R	1.023	1.00
90_R	473_M	1.019	1.00
404_H	436_T	1.017	1.00
89_E	468_S	1.014	1.00
39_A	104_I	1.013	1.00
213_H	229_E	1.007	1.00
167_N	354_V	1.005	1.00
53_S	77_H	1.005	1.00
82_V	91_I	0.999	1.00
187_F	205_C	0.996	1.00
420_S	461_I	0.996	1.00
460_A	463_K	0.990	1.00
185_K	210_G	0.988	1.00
249_L	279_A	0.987	1.00
349_I	380_T	0.985	1.00
449_H	452_E	0.985	1.00
23_Q	216_T	0.982	1.00
305_V	319_P	0.982	1.00
484_I	492_I	0.981	1.00
414_E	494_R	0.981	1.00
46_R	119_Q	0.979	1.00
48_S	102_L	0.976	1.00
27_L	32_L	0.969	1.00
303_T	391_I	0.968	1.00
36_S	71_G	0.963	1.00
463_K	466_A	0.962	1.00
161_V	355_S	0.962	1.00
401_I	440_L	0.962	1.00
275_S	279_A	0.962	1.00
152_S	489_N	0.959	1.00
39_A	68_S	0.956	1.00
351_G	354_V	0.956	1.00
86_I	94_I	0.950	1.00
247_M	435_G	0.949	1.00
45_K	131_G	0.949	1.00
54_P	99_G	0.947	1.00
93_K	96_E	0.946	1.00
427_V	484_I	0.946	1.00
329_I	391_I	0.944	1.00
331_I	339_L	0.943	1.00
106_A	109_L	0.939	1.00
348_V	370_F	0.938	1.00
89_E	93_K	0.933	1.00
83_D	194_S	0.932	1.00
170_S	352_P	0.931	1.00
20_F	66_I	0.930	1.00
149_I	296_T	0.928	1.00
89_E	92_A	0.927	1.00
170_S	326_D	0.926	1.00
416_H	465_L	0.923	1.00
59_G	62_E	0.922	1.00
246_Q	273_P	0.921	1.00
43_I	72_S	0.920	1.00
69_F	79_Y	0.916	1.00
17_T	211_T	0.914	1.00
420_S	460_A	0.913	1.00
188_L	215_V	0.912	1.00
279_A	282_E	0.911	1.00
56_L	103_L	0.909	1.00
116_Q	119_Q	0.909	1.00
93_K	150_Y	0.908	1.00
63_P	67_V	0.908	1.00
319_P	390_Q	0.900	1.00
7_I	11_A	0.898	1.00
18_D	28_T	0.895	1.00
383_A	395_G	0.894	1.00
172_T	207_Q	0.892	1.00
41_A	44_Q	0.892	1.00
245_V	280_L	0.885	1.00
25_Q	35_Q	0.885	1.00
24_G	232_K	0.884	1.00
316_E	386_I	0.884	1.00
419_Q	464_E	0.884	1.00
171_F	300_V	0.883	1.00
272_L	277_A	0.882	1.00
32_L	36_S	0.879	1.00
21_R	186_I	0.879	1.00
266_M	292_T	0.879	1.00
329_I	347_I	0.878	1.00
495_K	499_E	0.874	1.00
264_T	290_F	0.872	1.00
64_H	67_V	0.872	1.00
331_I	391_I	0.871	1.00
205_C	212_L	0.871	1.00
41_A	132_G	0.869	1.00
163_I	299_T	0.868	1.00
403_L	430_P	0.866	1.00
403_L	476_R	0.865	1.00
60_H	108_G	0.863	1.00
57_V	79_Y	0.862	1.00
92_A	117_Q	0.861	1.00
196_D	295_P	0.860	1.00
333_D	343_E	0.858	1.00
40_A	75_A	0.846	1.00
239_T	301_A	0.843	1.00
9_T	12_E	0.840	1.00
72_S	79_Y	0.838	1.00
31_E	35_Q	0.836	1.00
69_F	199_V	0.833	1.00
461_I	478_F	0.832	1.00
43_I	104_I	0.830	1.00
231_K	258_L	0.829	1.00
20_F	63_P	0.827	1.00
196_D	300_V	0.826	1.00
342_G	387_Q	0.823	1.00
146_F	165_A	0.822	1.00
56_L	80_I	0.822	1.00
93_K	361_E	0.819	1.00
163_I	355_S	0.814	1.00
111_I	114_V	0.813	1.00
66_I	214_C	0.811	1.00
460_A	464_E	0.811	1.00
33_W	36_S	0.808	1.00
8_Q	12_E	0.805	1.00
44_Q	136_Q	0.805	1.00
125_E	128_E	0.804	1.00
334_E	346_E	0.803	1.00
184_G	236_N	0.796	1.00
35_Q	63_P	0.796	1.00
236_N	263_D	0.792	1.00
17_T	183_G	0.790	1.00
6_A	173_D	0.790	1.00
101_E	119_Q	0.786	1.00
363_E	366_E	0.785	1.00
446_P	450_E	0.785	1.00
347_I	391_I	0.785	1.00
190_Q	244_F	0.785	1.00
69_F	73_V	0.784	1.00
34_E	133_S	0.783	1.00
298_A	354_V	0.783	1.00
46_R	102_L	0.782	1.00
241_T	244_F	0.782	1.00
445_V	483_H	0.781	1.00
336_G	348_V	0.780	1.00
245_V	267_F	0.779	1.00
264_T	288_K	0.779	1.00
370_F	373_E	0.777	1.00
399_F	414_E	0.774	1.00
67_V	71_G	0.774	1.00
462_K	474_I	0.773	1.00
186_I	234_G	0.769	1.00
328_N	377_A	0.765	1.00
332_M	338_P	0.762	1.00
38_R	42_A	0.759	1.00
427_V	497_I	0.759	1.00
140_V	165_A	0.757	1.00
224_K	228_E	0.756	1.00
246_Q	250_M	0.752	1.00
48_S	75_A	0.750	1.00
7_I	70_L	0.749	1.00
384_G	391_I	0.748	1.00
25_Q	64_H	0.746	1.00
330_F	350_A	0.746	1.00
329_I	384_G	0.745	1.00
228_E	231_K	0.744	1.00
298_A	378_Y	0.741	1.00
6_A	10_H	0.740	1.00
47_I	77_H	0.740	1.00
32_L	66_I	0.740	1.00
72_S	75_A	0.739	1.00
471_A	474_I	0.737	1.00
80_I	100_A	0.735	1.00
114_V	117_Q	0.734	1.00
246_Q	279_A	0.733	1.00
7_I	33_W	0.733	1.00
59_G	65_M	0.731	1.00
422_Y	447_E	0.729	1.00
251_D	254_F	0.729	1.00
432_Q	435_G	0.728	1.00
62_E	106_A	0.728	1.00
427_V	492_I	0.726	1.00
41_A	136_Q	0.726	1.00
446_P	452_E	0.726	1.00
431_Y	439_Y	0.726	1.00
197_L	268_C	0.725	1.00
200_M	239_T	0.724	1.00
275_S	278_K	0.724	1.00
145_T	164_S	0.724	1.00
5_H	8_Q	0.724	1.00
298_A	349_I	0.723	1.00
432_Q	437_V	0.719	1.00
5_H	9_T	0.719	1.00
94_I	160_G	0.719	1.00
147_Y	163_I	0.716	1.00
123_A	127_L	0.716	1.00
26_S	211_T	0.715	1.00
171_F	299_T	0.715	1.00
230_L	235_L	0.714	1.00
146_F	168_L	0.713	1.00
257_D	260_P	0.712	1.00
79_Y	199_V	0.711	1.00
123_A	126_L	0.710	1.00
262_A	265_F	0.709	1.00
298_A	302_V	0.709	1.00
195_F	406_Y	0.708	1.00
403_L	440_L	0.708	1.00
253_G	279_A	0.708	1.00
58_Y	103_L	0.707	1.00
292_T	301_A	0.706	1.00
171_F	200_M	0.706	1.00
89_E	157_N	0.705	1.00
465_L	469_L	0.705	1.00
365_T	369_F	0.704	1.00
41_A	131_G	0.703	1.00
253_G	256_Q	0.702	1.00
24_G	233_S	0.699	1.00
369_F	379_R	0.699	1.00
379_R	397_L	0.699	1.00
182_S	263_D	0.698	1.00
361_E	365_T	0.698	1.00
56_L	98_S	0.696	1.00
384_G	394_Q	0.694	1.00
218_D	244_F	0.693	1.00
225_V	229_E	0.692	1.00
239_T	292_T	0.690	1.00
411_E	414_E	0.690	1.00
429_I	498_G	0.689	1.00
416_H	464_E	0.688	1.00
88_S	113_A	0.688	1.00
284_F	287_A	0.687	1.00
188_L	229_E	0.687	1.00
432_Q	436_T	0.687	1.00
41_A	133_S	0.685	1.00
39_A	43_I	0.683	1.00
228_E	257_D	0.682	1.00
422_Y	446_P	0.681	1.00
58_Y	109_L	0.679	1.00
55_I	102_L	0.679	1.00
181_V	237_V	0.679	1.00
16_Q	28_T	0.678	1.00
178_D	325_P	0.677	1.00
176_C	204_P	0.676	1.00
417_V	426_A	0.676	1.00
44_Q	138_Q	0.676	1.00
354_V	378_Y	0.675	1.00
68_S	72_S	0.675	1.00
14_Y	30_Q	0.674	1.00
69_F	203_Y	0.674	1.00
40_A	71_G	0.674	1.00
290_F	306_E	0.667	1.00
256_Q	259_L	0.666	1.00
265_F	280_L	0.666	1.00
187_F	237_V	0.665	1.00
105_H	109_L	0.664	1.00
370_F	377_A	0.663	1.00
113_A	116_Q	0.662	1.00
272_L	289_I	0.660	1.00
171_F	301_A	0.655	1.00
10_H	209_G	0.654	1.00
87_P	90_R	0.653	1.00
246_Q	275_S	0.652	1.00
167_N	356_R	0.652	1.00
459_S	462_K	0.651	1.00
111_I	115_G	0.650	1.00
118_I	121_V	0.649	1.00
11_A	15_P	0.649	1.00
458_T	477_K	0.648	1.00
39_A	42_A	0.647	1.00
324_K	327_M	0.647	1.00
291_N	318_L	0.647	1.00
415_F	419_Q	0.644	1.00
51_K	140_V	0.643	1.00
215_V	226_L	0.642	1.00
190_Q	241_T	0.641	1.00
36_S	39_A	0.641	1.00
188_L	230_L	0.640	1.00
295_P	298_A	0.640	1.00
70_L	203_Y	0.639	1.00
336_G	370_F	0.639	1.00
427_V	494_R	0.638	1.00
341_E	387_Q	0.637	1.00
51_K	138_Q	0.636	1.00
444_I	461_I	0.634	1.00
424_R	446_P	0.633	1.00
143_H	356_R	0.632	1.00
410_L	494_R	0.632	1.00
157_N	361_E	0.632	1.00
293_Y	302_V	0.631	1.00
281_L	288_K	0.631	1.00
230_L	238_W	0.629	1.00
115_G	119_Q	0.627	1.00
231_K	260_P	0.627	1.00
44_Q	135_S	0.627	1.00
59_G	68_S	0.626	1.00
14_Y	209_G	0.626	1.00
42_A	131_G	0.626	1.00
433_P	436_T	0.625	1.00
200_M	301_A	0.625	1.00
417_V	465_L	0.624	1.00
255_S	283_R	0.623	1.00
105_H	110_S	0.622	1.00
80_I	150_Y	0.620	1.00
229_E	232_K	0.619	1.00
462_K	465_L	0.619	1.00
191_A	239_T	0.618	1.00
410_L	428_V	0.617	1.00
172_T	203_Y	0.616	1.00
59_G	104_I	0.616	1.00
443_A	479_I	0.614	1.00
14_Y	183_G	0.613	1.00
12_E	33_W	0.611	1.00
27_L	31_E	0.610	1.00
36_S	40_A	0.609	1.00
173_D	177_A	0.608	1.00
124_E	128_E	0.606	1.00
423_V	444_I	0.605	1.00
64_H	106_A	0.604	1.00
201_D	239_T	0.603	1.00
200_M	300_V	0.602	1.00
231_K	261_H	0.602	1.00
37_D	135_S	0.602	1.00
320_V	384_G	0.600	1.00
37_D	134_V	0.600	1.00
54_P	360_G	0.599	1.00
135_S	138_Q	0.599	1.00
97_S	359_L	0.598	1.00
423_V	426_A	0.598	1.00
276_V	279_A	0.598	1.00
420_S	423_V	0.598	1.00
355_S	368_A	0.598	1.00
6_A	169_Q	0.597	1.00
485_Q	497_I	0.597	1.00
173_D	207_Q	0.597	1.00
171_F	175_I	0.597	1.00
398_D	438_E	0.597	1.00
403_L	436_T	0.596	1.00
424_R	448_E	0.596	1.00
295_P	380_T	0.595	1.00
211_T	233_S	0.594	1.00
67_V	123_A	0.593	1.00
20_F	212_L	0.592	1.00
438_E	498_G	0.591	1.00
41_A	134_V	0.588	1.00
99_G	359_L	0.587	1.00
38_R	133_S	0.587	1.00
59_G	106_A	0.586	1.00
45_K	129_N	0.585	1.00
44_Q	137_D	0.585	1.00
78_P	148_I	0.582	1.00
267_F	289_I	0.582	1.00
361_E	367_K	0.582	1.00
238_W	265_F	0.580	1.00
6_A	207_Q	0.579	1.00
272_L	291_N	0.578	1.00
226_L	230_L	0.578	1.00
147_Y	199_V	0.577	1.00
416_H	469_L	0.577	1.00
148_I	162_Q	0.577	1.00
96_E	117_Q	0.576	1.00
114_V	119_Q	0.576	1.00
477_K	480_Y	0.573	1.00
22_S	216_T	0.573	1.00
189_N	212_L	0.572	1.00
451_F	457_L	0.571	1.00
59_G	105_H	0.571	1.00
41_A	45_K	0.571	1.00
147_Y	168_L	0.571	1.00
338_P	348_V	0.571	1.00
271_V	393_C	0.570	1.00
197_L	266_M	0.569	1.00
344_K	397_L	0.567	1.00
41_A	135_S	0.566	1.00
431_Y	443_A	0.566	1.00
331_I	347_I	0.566	1.00
448_E	451_F	0.565	1.00
192_P	195_F	0.565	1.00
190_Q	240_S	0.564	1.00
38_R	41_A	0.563	1.00
69_F	202_L	0.562	1.00
97_S	160_G	0.561	1.00
111_I	116_Q	0.560	1.00
181_V	210_G	0.560	1.00
331_I	345_G	0.560	1.00
280_L	289_I	0.559	1.00
401_I	430_P	0.559	1.00
144_E	165_A	0.557	1.00
331_I	385_F	0.557	1.00
78_P	359_L	0.557	1.00
227_F	259_L	0.556	1.00
173_D	176_C	0.555	1.00
18_D	186_I	0.555	1.00
239_T	268_C	0.555	1.00
81_P	149_I	0.554	1.00
181_V	185_K	0.554	1.00
37_D	44_Q	0.553	1.00
357_G	362_P	0.552	1.00
278_K	281_L	0.552	1.00
414_E	442_A	0.551	1.00
43_I	102_L	0.548	1.00
186_I	189_N	0.548	1.00
57_V	65_M	0.547	1.00
189_N	214_C	0.547	1.00
29_Y	210_G	0.547	1.00
194_S	406_Y	0.547	1.00
242_P	270_E	0.545	1.00
90_R	412_E	0.545	1.00
415_F	418_R	0.545	1.00
332_M	377_A	0.544	1.00
57_V	72_S	0.544	1.00
112_D	115_G	0.544	1.00
156_G	409_E	0.543	1.00
425_S	484_I	0.543	1.00
115_G	118_I	0.542	1.00
86_I	91_I	0.540	1.00
161_V	296_T	0.540	1.00
247_M	250_M	0.540	1.00
114_V	120_T	0.538	1.00
410_L	430_P	0.537	1.00
78_P	81_P	0.537	1.00
495_K	498_G	0.536	1.00
483_H	486_M	0.534	1.00
249_L	276_V	0.534	1.00
54_P	100_A	0.533	1.00
189_N	198_S	0.531	1.00
21_R	24_G	0.531	1.00
112_D	116_Q	0.530	1.00
35_Q	127_L	0.530	1.00
98_S	148_I	0.529	1.00
413_I	440_L	0.528	1.00
35_Q	39_A	0.528	1.00
474_I	478_F	0.526	1.00
218_D	226_L	0.526	1.00
395_G	410_L	0.525	1.00
268_C	292_T	0.525	1.00
107_A	122_S	0.525	1.00
60_H	109_L	0.524	1.00
98_S	160_G	0.524	1.00
292_T	304_S	0.523	1.00
43_I	77_H	0.522	1.00
52_K	77_H	0.520	1.00
39_A	123_A	0.520	1.00
82_V	95_I	0.519	1.00
188_L	226_L	0.519	1.00
403_L	438_E	0.518	1.00
267_F	291_N	0.517	1.00
386_I	389_G	0.517	1.00
187_F	210_G	0.516	1.00
278_K	317_S	0.516	1.00
265_F	287_A	0.515	1.00
226_L	244_F	0.514	1.00
80_I	94_I	0.514	1.00
175_I	200_M	0.514	1.00
77_H	102_L	0.512	1.00
277_A	291_N	0.511	1.00
5_H	139_W	0.511	1.00
174_W	178_D	0.511	1.00
29_Y	206_L	0.510	1.00
303_T	320_V	0.509	1.00
362_P	365_T	0.509	1.00
197_L	292_T	0.509	1.00
349_I	354_V	0.507	1.00
426_A	465_L	0.506	1.00
169_Q	173_D	0.506	1.00
227_F	248_C	0.505	1.00
277_A	281_L	0.504	1.00
240_S	265_F	0.504	1.00
20_F	27_L	0.502	1.00
399_F	410_L	0.502	1.00
7_I	36_S	0.501	1.00
55_I	104_I	0.501	1.00
42_A	127_L	0.500	1.00
60_H	217_K	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3e7wA	1	0.998	100	0.108	Contact Map
3tsyA	2	0.7793	100	0.118	Contact Map
2vsqA	1	0.9761	100	0.123	Contact Map
3g7sA	2	0.9006	100	0.13	Contact Map
3ni2A	1	0.9702	100	0.134	Contact Map
3etcA	2	0.9384	100	0.135	Contact Map
3o83A	1	0.7694	100	0.136	Contact Map
3l8cA	1	0.992	100	0.137	Contact Map
1mdbA	1	0.9583	100	0.139	Contact Map
3wvnA	1	0.7435	100	0.14	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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