TLPB - BACSU - GREMLIN Contacts

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TLPB - Methyl-accepting chemotaxis protein TlpB

UniProt:	P39217	Sequences: MGKFIQWIKQPSISKPLIAAFLAVLILPVGVLAYFSYQSAWNALDRELISSAKGNVEELNSTLQNKLEDKVKAIDYYSETVDKDILLGKNKTLLKEKFKQYTTLNDDVGAIYAASEDKKLYKYPDSGVPKGFDPTGRDWYKQAVAEKGQAVFSEPYTDEATGDIVVTISKQLKDGSGVIALDLNLDEVLTASKRIKIGKEGFAFITTGNKKYIAHPTIKPGTTGSGDWTNQVYSKKEGSFEYTFEGKEKKMAFTTNKLTGWKIAGTYFVSELQDASSPVLNTAVIILCVSIVIGGILILYIIRAITKPLRKLVSTSAKISSGDLTEVIDIHSKNEFGQLGESFNEMSASLRSVIGVIQTSVENVASSSEELTASAAQTSKATEHITLAIEQFSDGNEAQSEKLETSSNHLSQMNEGISKVAQASSTITKSSIQSSEAAGSGEKLVEHTVGQMKTIDQSVQKAEAVVKGLETKSQDITSILNVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIEGLIQEIVREISTSLSMFQSVNHEVKEGLQITDQTAESFKQIYEMTTQISGELQNLNATVEQLSAGSQEVSSAVEDISAVAKESSAGIQDIAASAEEQLASMEEISSSAETLANMAEELQDITKKFKIES	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	662 (617)
Sequences:	7474 (6475)
Seq/√Len:	260.7

ECOLI - AER MCP3 MCP4 MCP1 MCP2
BACSU - TLPB MCPA MCPB TLPA MCPC YVAQ TLPC YOAH
HALSA - HTR4 HTR2 Q9HRA1 COST Q9HR88 Q9HRN6 Q9HP10 Q9HQX8 Q9HPA2 Q9HS86 HTR7 Q9HPQ5 HTR9 HMAT HTR1 Q9HQT5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
332_S	337_G	6.709	1.00
327_V	351_R	4.203	1.00
16_P	334_N	4.040	1.00
318_K	323_D	3.524	1.00
334_N	337_G	3.338	1.00
34_Y	38_Q	3.267	1.00
14_S	303_R	3.143	1.00
316_S	346_M	2.860	1.00
498_A	519_R	2.614	1.00
200_E	271_E	2.609	1.00
471_T	474_Q	2.599	1.00
112_Y	180_A	2.579	1.00
441_G	574_I	2.542	1.00
455_I	560_G	2.524	1.00
465_V	546_S	2.519	1.00
327_V	344_N	2.486	1.00
302_I	306_T	2.460	1.00
255_T	262_K	2.450	1.00
317_A	338_Q	2.438	1.00
204_F	264_A	2.364	1.00
481_N	485_G	2.320	1.00
12_S	15_K	2.281	1.00
327_V	348_A	2.256	1.00
477_T	540_V	2.224	1.00
498_A	516_E	2.218	1.00
562_Q	566_Q	2.189	1.00
303_R	307_K	2.169	1.00
248_E	269_V	2.166	1.00
525_S	529_A	2.166	1.00
468_G	542_E	2.150	1.00
472_K	542_E	2.146	1.00
641_A	644_L	2.143	1.00
312_L	316_S	2.133	1.00
36_S	283_A	2.120	1.00
520_K	523_V	2.102	1.00
281_N	285_I	2.099	1.00
285_I	289_V	2.082	1.00
141_K	145_A	2.076	1.00
472_K	538_E	2.066	1.00
449_V	568_A	2.060	1.00
437_A	573_Q	2.051	1.00
319_I	346_M	2.039	1.00
601_E	604_S	2.033	1.00
482_V	528_S	2.016	1.00
167_T	182_D	2.015	1.00
238_G	253_F	2.015	1.00
475_D	478_S	2.005	1.00
473_S	543_I	2.004	1.00
158_D	161_T	1.997	1.00
479_I	535_L	1.997	1.00
516_E	519_R	1.997	1.00
344_N	347_S	1.995	1.00
618_A	621_Q	1.985	1.00
202_F	216_P	1.961	1.00
618_A	622_D	1.953	1.00
197_I	201_G	1.924	1.00
629_E	632_A	1.916	1.00
566_Q	569_E	1.911	1.00
318_K	326_E	1.905	1.00
133_D	136_G	1.902	1.00
565_D	569_E	1.901	1.00
440_S	443_K	1.895	1.00
622_D	625_A	1.893	1.00
571_F	574_I	1.892	1.00
441_G	571_F	1.889	1.00
452_M	560_G	1.889	1.00
448_T	567_T	1.880	1.00
230_N	234_S	1.880	1.00
163_D	186_D	1.854	1.00
115_S	119_K	1.853	1.00
419_K	422_Q	1.848	1.00
316_S	343_F	1.846	1.00
142_Q	145_A	1.842	1.00
470_E	547_L	1.841	1.00
447_H	450_G	1.830	1.00
156_Y	167_T	1.808	1.00
99_K	103_T	1.800	1.00
628_E	632_A	1.791	1.00
313_V	338_Q	1.791	1.00
551_Q	555_H	1.778	1.00
427_I	585_L	1.776	1.00
198_G	201_G	1.747	1.00
580_Q	583_G	1.739	1.00
443_K	447_H	1.737	1.00
338_Q	341_E	1.722	1.00
590_A	593_E	1.701	1.00
484_N	529_A	1.700	1.00
298_I	302_I	1.697	1.00
313_V	342_S	1.693	1.00
316_S	339_L	1.693	1.00
478_S	481_N	1.689	1.00
330_I	344_N	1.647	1.00
555_H	558_K	1.645	1.00
40_A	279_V	1.644	1.00
590_A	594_Q	1.642	1.00
202_F	215_H	1.637	1.00
378_T	382_T	1.631	1.00
593_E	597_A	1.631	1.00
33_A	287_L	1.630	1.00
466_V	546_S	1.627	1.00
154_E	209_N	1.626	1.00
579_T	583_G	1.615	1.00
405_T	408_N	1.605	1.00
533_E	537_Q	1.595	1.00
198_G	271_E	1.593	1.00
469_L	539_I	1.592	1.00
429_K	433_Q	1.590	1.00
635_E	639_S	1.589	1.00
373_A	377_Q	1.583	1.00
113_A	172_L	1.583	1.00
466_V	547_L	1.578	1.00
366_S	370_E	1.569	1.00
608_D	611_A	1.566	1.00
152_F	168_I	1.550	1.00
351_R	355_G	1.548	1.00
319_I	347_S	1.543	1.00
309_L	339_L	1.535	1.00
465_V	545_T	1.530	1.00
436_E	440_S	1.528	1.00
600_Q	604_S	1.526	1.00
33_A	37_Y	1.520	1.00
594_Q	597_A	1.516	1.00
64_Q	68_E	1.503	1.00
450_G	454_T	1.502	1.00
317_A	342_S	1.501	1.00
140_Y	144_V	1.499	1.00
156_Y	182_D	1.497	1.00
461_K	464_A	1.486	1.00
339_L	343_F	1.486	1.00
413_M	599_S	1.484	1.00
471_T	475_D	1.482	1.00
401_E	404_E	1.472	1.00
447_H	566_Q	1.471	1.00
472_K	475_D	1.467	1.00
366_S	369_E	1.460	1.00
615_E	618_A	1.458	1.00
280_L	284_V	1.454	1.00
495_L	503_R	1.453	1.00
118_K	135_T	1.449	1.00
244_F	249_K	1.447	1.00
187_E	190_T	1.444	1.00
555_H	559_E	1.442	1.00
186_D	190_T	1.429	1.00
452_M	455_I	1.428	1.00
348_A	352_S	1.428	1.00
95_K	99_K	1.418	1.00
607_E	611_A	1.416	1.00
611_A	615_E	1.410	1.00
247_K	268_F	1.410	1.00
316_S	342_S	1.410	1.00
202_F	266_T	1.406	1.00
369_E	373_A	1.405	1.00
527_D	531_E	1.404	1.00
28_P	290_S	1.396	1.00
468_G	471_T	1.392	1.00
251_M	264_A	1.392	1.00
402_K	608_D	1.385	1.00
151_V	169_S	1.384	1.00
446_E	450_G	1.382	1.00
289_V	293_I	1.378	1.00
458_S	552_S	1.373	1.00
190_T	193_K	1.371	1.00
190_T	194_R	1.368	1.00
40_A	44_L	1.362	1.00
120_L	123_Y	1.359	1.00
155_P	164_I	1.349	1.00
436_E	439_G	1.339	1.00
411_S	415_E	1.337	1.00
22_L	295_G	1.334	1.00
38_Q	42_N	1.331	1.00
569_E	573_Q	1.330	1.00
312_L	339_L	1.329	1.00
327_V	347_S	1.329	1.00
573_Q	576_E	1.328	1.00
223_T	227_D	1.325	1.00
425_S	429_K	1.325	1.00
433_Q	436_E	1.322	1.00
453_K	565_D	1.308	1.00
292_V	296_I	1.305	1.00
75_D	150_A	1.304	1.00
199_K	271_E	1.300	1.00
278_P	282_T	1.296	1.00
611_A	614_K	1.292	1.00
559_E	562_Q	1.284	1.00
108_V	181_L	1.282	1.00
494_A	519_R	1.282	1.00
376_A	380_K	1.280	1.00
459_V	557_V	1.274	1.00
137_R	158_D	1.268	1.00
398_A	401_E	1.264	1.00
420_V	592_V	1.263	1.00
530_K	534_G	1.258	1.00
232_V	264_A	1.255	1.00
52_A	56_V	1.253	1.00
143_A	169_S	1.250	1.00
138_D	142_Q	1.244	1.00
375_A	379_S	1.244	1.00
91_K	95_K	1.243	1.00
466_V	550_F	1.242	1.00
527_D	530_K	1.237	1.00
630_Q	634_M	1.235	1.00
224_G	227_D	1.234	1.00
426_T	429_K	1.233	1.00
432_I	436_E	1.231	1.00
569_E	572_K	1.229	1.00
401_E	405_T	1.228	1.00
379_S	382_T	1.228	1.00
312_L	343_F	1.225	1.00
636_E	639_S	1.225	1.00
621_Q	625_A	1.220	1.00
317_A	345_E	1.217	1.00
422_Q	426_T	1.216	1.00
491_N	519_R	1.210	1.00
29_V	32_L	1.208	1.00
37_Y	280_L	1.207	1.00
241_E	269_V	1.205	1.00
558_K	562_Q	1.204	1.00
630_Q	644_L	1.203	1.00
431_S	581_I	1.202	1.00
13_I	336_F	1.202	1.00
249_K	268_F	1.202	1.00
523_V	527_D	1.201	1.00
141_K	144_V	1.201	1.00
288_C	292_V	1.199	1.00
100_Q	103_T	1.193	1.00
450_G	453_K	1.191	1.00
47_E	51_S	1.190	1.00
143_A	178_V	1.190	1.00
507_Y	518_V	1.184	1.00
632_A	635_E	1.180	1.00
469_L	546_S	1.177	1.00
163_D	184_N	1.175	1.00
361_V	368_S	1.174	1.00
71_V	75_D	1.167	1.00
203_A	265_G	1.167	1.00
25_L	28_P	1.163	1.00
370_E	373_A	1.160	1.00
319_I	324_L	1.159	1.00
637_I	644_L	1.159	1.00
25_L	294_G	1.158	1.00
169_S	178_V	1.158	1.00
339_L	346_M	1.158	1.00
330_I	334_N	1.158	1.00
18_I	22_L	1.156	1.00
243_T	248_E	1.154	1.00
319_I	350_L	1.154	1.00
114_A	134_P	1.152	1.00
155_P	207_T	1.150	1.00
135_T	140_Y	1.150	1.00
324_L	354_I	1.147	1.00
312_L	340_G	1.145	1.00
544_S	548_S	1.144	1.00
137_R	159_E	1.141	1.00
572_K	576_E	1.141	1.00
66_K	70_K	1.139	1.00
453_K	457_Q	1.137	1.00
269_V	273_Q	1.135	1.00
485_G	488_D	1.134	1.00
530_K	533_E	1.133	1.00
249_K	266_T	1.132	1.00
443_K	446_E	1.128	1.00
408_N	412_Q	1.128	1.00
230_N	233_Y	1.127	1.00
222_T	225_S	1.126	1.00
150_A	170_K	1.124	1.00
625_A	628_E	1.122	1.00
282_T	285_I	1.121	1.00
74_I	181_L	1.119	1.00
11_P	19_A	1.117	1.00
41_W	45_D	1.116	1.00
231_Q	235_K	1.116	1.00
35_F	39_S	1.116	1.00
308_P	332_S	1.114	1.00
479_I	536_I	1.113	1.00
319_I	343_F	1.112	1.00
229_T	232_V	1.112	1.00
14_S	18_I	1.108	1.00
519_R	523_V	1.107	1.00
469_L	543_I	1.106	1.00
464_A	468_G	1.103	1.00
442_E	572_K	1.102	1.00
157_T	162_G	1.095	1.00
429_K	432_I	1.093	1.00
438_A	575_Y	1.092	1.00
460_Q	464_A	1.091	1.00
328_I	344_N	1.091	1.00
284_V	288_C	1.085	1.00
439_G	443_K	1.081	1.00
323_D	326_E	1.078	1.00
409_H	412_Q	1.076	1.00
343_F	347_S	1.075	1.00
11_P	15_K	1.075	1.00
452_M	564_T	1.071	1.00
457_Q	460_Q	1.071	1.00
526_A	530_K	1.068	1.00
484_N	533_E	1.068	1.00
71_V	152_F	1.067	1.00
560_G	567_T	1.067	1.00
457_Q	461_K	1.066	1.00
451_Q	559_E	1.065	1.00
455_I	557_V	1.063	1.00
277_S	280_L	1.063	1.00
29_V	287_L	1.062	1.00
448_T	564_T	1.062	1.00
463_E	550_F	1.062	1.00
21_F	298_I	1.060	1.00
537_Q	541_R	1.060	1.00
562_Q	565_D	1.059	1.00
583_G	586_Q	1.059	1.00
625_A	629_E	1.059	1.00
231_Q	236_K	1.054	1.00
399_Q	403_L	1.051	1.00
207_T	211_K	1.051	1.00
576_E	580_Q	1.048	1.00
475_D	531_E	1.046	1.00
618_A	625_A	1.043	1.00
597_A	601_E	1.043	1.00
318_K	346_M	1.041	1.00
315_T	328_I	1.041	1.00
313_V	339_L	1.040	1.00
204_F	266_T	1.040	1.00
322_G	339_L	1.037	1.00
17_L	21_F	1.035	1.00
413_M	416_G	1.030	1.00
465_V	549_M	1.030	1.00
418_S	422_Q	1.030	1.00
45_D	49_I	1.030	1.00
72_K	75_D	1.028	1.00
357_I	364_V	1.026	1.00
356_V	359_T	1.023	1.00
277_S	281_N	1.020	1.00
242_Y	249_K	1.017	1.00
281_N	284_V	1.015	1.00
36_S	40_A	1.012	1.00
576_E	579_T	1.012	1.00
459_V	550_F	1.012	1.00
130_K	134_P	1.011	1.00
247_K	270_S	1.011	1.00
460_Q	554_N	1.009	1.00
534_G	538_E	1.008	1.00
464_A	467_K	1.008	1.00
295_G	299_L	1.006	1.00
524_Q	531_E	1.002	1.00
421_A	424_S	1.001	1.00
112_Y	182_D	1.000	1.00
313_V	317_A	0.999	1.00
122_K	125_D	0.999	1.00
492_L	499_I	0.997	1.00
30_G	34_Y	0.997	1.00
315_T	343_F	0.994	1.00
524_Q	527_D	0.990	1.00
316_S	319_I	0.987	1.00
154_E	207_T	0.985	1.00
583_G	587_N	0.982	1.00
308_P	336_F	0.978	1.00
536_I	540_V	0.976	1.00
479_I	528_S	0.976	1.00
330_I	340_G	0.972	1.00
424_S	427_I	0.970	1.00
438_A	441_G	0.968	1.00
410_L	606_V	0.963	1.00
467_K	471_T	0.963	1.00
638_S	642_E	0.963	1.00
494_A	518_V	0.963	1.00
412_Q	598_G	0.962	1.00
302_I	305_I	0.961	1.00
488_D	499_I	0.961	1.00
610_S	614_K	0.958	1.00
311_K	329_D	0.958	1.00
541_R	545_T	0.955	1.00
548_S	551_Q	0.954	1.00
620_I	627_A	0.953	1.00
358_Q	362_E	0.953	1.00
16_P	304_A	0.952	1.00
634_M	644_L	0.950	1.00
373_A	376_A	0.948	1.00
479_I	529_A	0.946	1.00
153_S	156_Y	0.943	1.00
26_I	30_G	0.943	1.00
399_Q	613_A	0.943	1.00
33_A	283_A	0.940	1.00
516_E	520_K	0.936	1.00
352_S	356_V	0.936	1.00
204_F	215_H	0.935	1.00
590_A	597_A	0.933	1.00
347_S	351_R	0.932	1.00
375_A	378_T	0.931	1.00
136_G	141_K	0.929	1.00
11_P	16_P	0.928	1.00
630_Q	637_I	0.927	1.00
60_N	256_N	0.927	1.00
148_G	171_Q	0.926	1.00
324_L	350_L	0.926	1.00
375_A	382_T	0.925	1.00
211_K	214_A	0.923	1.00
412_Q	416_G	0.921	1.00
167_T	180_A	0.916	1.00
368_S	375_A	0.915	1.00
445_V	448_T	0.914	1.00
454_T	556_E	0.913	1.00
614_K	618_A	0.910	1.00
153_S	169_S	0.909	1.00
474_Q	544_S	0.909	1.00
70_K	73_A	0.908	1.00
296_I	300_Y	0.908	1.00
340_G	344_N	0.908	1.00
439_G	579_T	0.907	1.00
157_T	164_I	0.906	1.00
632_A	636_E	0.904	1.00
447_H	563_I	0.902	1.00
412_Q	415_E	0.901	1.00
518_V	524_Q	0.899	1.00
227_D	230_N	0.896	1.00
445_V	571_F	0.896	1.00
403_L	609_I	0.895	1.00
468_G	545_T	0.890	1.00
522_A	525_S	0.889	1.00
451_Q	454_T	0.887	1.00
318_K	321_S	0.886	1.00
45_D	273_Q	0.885	1.00
623_I	626_S	0.884	1.00
406_S	605_A	0.883	1.00
362_E	366_S	0.883	1.00
417_I	595_L	0.882	1.00
619_G	622_D	0.881	1.00
322_G	346_M	0.878	1.00
411_S	414_N	0.878	1.00
462_A	550_F	0.876	1.00
637_I	641_A	0.875	1.00
139_W	158_D	0.873	1.00
68_E	71_V	0.872	1.00
546_S	550_F	0.871	1.00
456_D	561_L	0.869	1.00
139_W	182_D	0.869	1.00
279_V	283_A	0.868	1.00
294_G	298_I	0.867	1.00
314_S	317_A	0.866	1.00
371_L	375_A	0.866	1.00
641_A	645_A	0.864	1.00
343_F	346_M	0.863	1.00
463_E	551_Q	0.861	1.00
333_K	337_G	0.858	1.00
315_T	326_E	0.858	1.00
226_G	230_N	0.854	1.00
122_K	126_S	0.851	0.99
531_E	534_G	0.851	0.99
140_Y	178_V	0.851	0.99
440_S	566_Q	0.849	0.99
438_A	442_E	0.849	0.99
359_T	363_N	0.848	0.99
139_W	156_Y	0.848	0.99
133_D	137_R	0.848	0.99
425_S	593_E	0.847	0.99
379_S	383_E	0.847	0.99
435_S	439_G	0.847	0.99
467_K	551_Q	0.846	0.99
219_K	222_T	0.845	0.99
153_S	167_T	0.845	0.99
458_S	556_E	0.843	0.99
594_Q	598_G	0.842	0.99
20_A	301_I	0.841	0.99
114_A	137_R	0.841	0.99
114_A	139_W	0.841	0.99
110_A	115_S	0.840	0.99
409_H	413_M	0.839	0.99
311_K	314_S	0.839	0.99
564_T	568_A	0.837	0.99
458_S	461_K	0.835	0.99
56_V	265_G	0.832	0.99
199_K	274_D	0.832	0.99
56_V	60_N	0.831	0.99
134_P	140_Y	0.829	0.99
448_T	455_I	0.827	0.99
114_A	120_L	0.827	0.99
311_K	315_T	0.825	0.99
138_D	141_K	0.824	0.99
229_T	233_Y	0.823	0.99
353_V	357_I	0.823	0.99
11_P	333_K	0.822	0.99
74_I	170_K	0.822	0.99
552_S	555_H	0.822	0.99
421_A	596_S	0.820	0.99
119_K	133_D	0.816	0.99
148_G	173_K	0.816	0.99
478_S	482_V	0.816	0.99
304_A	307_K	0.816	0.99
92_T	96_E	0.810	0.99
306_T	310_R	0.809	0.99
463_E	546_S	0.809	0.99
177_G	182_D	0.808	0.99
459_V	553_V	0.808	0.99
37_Y	41_W	0.807	0.99
373_A	380_K	0.806	0.99
310_R	313_V	0.805	0.99
321_S	349_S	0.803	0.99
346_M	350_L	0.803	0.99
473_S	479_I	0.802	0.99
525_S	535_L	0.801	0.99
422_Q	425_S	0.797	0.99
73_A	76_Y	0.796	0.99
330_I	337_G	0.796	0.99
565_D	568_A	0.796	0.99
377_Q	380_K	0.796	0.99
64_Q	258_L	0.794	0.99
328_I	340_G	0.792	0.99
480_L	484_N	0.792	0.99
617_S	624_A	0.792	0.99
432_I	586_Q	0.791	0.99
158_D	165_V	0.790	0.99
581_I	585_L	0.789	0.99
479_I	525_S	0.789	0.99
371_L	382_T	0.788	0.99
177_G	180_A	0.784	0.99
355_G	359_T	0.784	0.99
93_L	96_E	0.784	0.99
85_I	89_K	0.783	0.99
399_Q	612_V	0.783	0.99
399_Q	413_M	0.783	0.99
407_S	412_Q	0.783	0.99
317_A	321_S	0.780	0.99
32_L	36_S	0.780	0.99
158_D	182_D	0.780	0.99
212_Y	215_H	0.780	0.99
96_E	99_K	0.779	0.99
208_G	260_G	0.778	0.99
601_E	605_A	0.778	0.99
560_G	571_F	0.777	0.99
197_I	271_E	0.775	0.99
415_E	419_K	0.774	0.99
119_K	126_S	0.774	0.99
441_G	445_V	0.773	0.99
444_L	566_Q	0.770	0.99
404_E	408_N	0.770	0.99
418_S	600_Q	0.770	0.99
337_G	340_G	0.770	0.99
69_D	72_K	0.769	0.99
406_S	602_V	0.769	0.99
16_P	332_S	0.767	0.99
413_M	595_L	0.767	0.99
553_V	560_G	0.767	0.99
132_F	137_R	0.766	0.99
431_S	585_L	0.765	0.99
119_K	123_Y	0.765	0.99
417_I	599_S	0.765	0.99
242_Y	251_M	0.763	0.99
169_S	180_A	0.762	0.99
118_K	121_Y	0.762	0.99
51_S	54_G	0.761	0.99
448_T	518_V	0.760	0.99
448_T	452_M	0.758	0.99
462_A	466_V	0.758	0.99
15_K	19_A	0.758	0.99
38_Q	41_W	0.757	0.99
250_K	269_V	0.757	0.99
330_I	341_E	0.756	0.99
470_E	474_Q	0.755	0.99
463_E	554_N	0.755	0.99
109_G	158_D	0.754	0.99
78_S	170_K	0.754	0.99
150_A	168_I	0.752	0.99
336_F	340_G	0.752	0.99
196_K	271_E	0.751	0.99
410_L	417_I	0.751	0.99
65_N	68_E	0.750	0.99
139_W	143_A	0.747	0.99
480_L	533_E	0.746	0.99
365_A	369_E	0.746	0.99
586_Q	590_A	0.746	0.99
410_L	413_M	0.744	0.99
59_L	62_T	0.744	0.99
475_D	538_E	0.744	0.99
462_A	549_M	0.743	0.99
100_Q	104_L	0.741	0.99
556_E	559_E	0.741	0.99
541_R	544_S	0.741	0.99
112_Y	120_L	0.740	0.99
71_V	150_A	0.740	0.99
625_A	632_A	0.740	0.99
139_W	178_V	0.739	0.99
347_S	350_L	0.738	0.99
165_V	182_D	0.737	0.99
538_E	542_E	0.736	0.99
434_S	578_T	0.735	0.99
469_L	479_I	0.733	0.98
462_A	553_V	0.733	0.98
427_I	434_S	0.731	0.98
473_S	560_G	0.730	0.98
357_I	641_A	0.729	0.98
110_A	124_P	0.729	0.98
50_S	54_G	0.728	0.98
308_P	337_G	0.728	0.98
359_T	362_E	0.727	0.98
428_T	432_I	0.726	0.98
480_L	532_I	0.726	0.98
13_I	335_E	0.725	0.98
36_S	279_V	0.725	0.98
633_S	637_I	0.724	0.98
454_T	457_Q	0.723	0.98
488_D	492_L	0.723	0.98
623_I	630_Q	0.722	0.98
491_N	498_A	0.718	0.98
492_L	520_K	0.718	0.98
627_A	634_M	0.717	0.98
374_S	378_T	0.716	0.98
470_E	544_S	0.715	0.98
564_T	567_T	0.715	0.98
345_E	348_A	0.714	0.98
313_V	336_F	0.714	0.98
274_D	278_P	0.713	0.98
278_P	281_N	0.713	0.98
111_I	179_I	0.713	0.98
440_S	570_S	0.710	0.98
349_S	352_S	0.710	0.98
11_P	14_S	0.710	0.98
587_N	590_A	0.710	0.98
344_N	348_A	0.709	0.98
168_I	183_L	0.708	0.98
403_L	410_L	0.707	0.98
255_T	260_G	0.707	0.98
356_V	636_E	0.706	0.98
322_G	353_V	0.705	0.98
346_M	349_S	0.705	0.98
139_W	180_A	0.705	0.98
414_N	599_S	0.704	0.98
231_Q	234_S	0.704	0.98
485_G	524_Q	0.702	0.98
482_V	522_A	0.701	0.98
137_R	143_A	0.700	0.98
90_N	93_L	0.700	0.98
312_L	328_I	0.700	0.98
564_T	574_I	0.699	0.98
408_N	411_S	0.695	0.98
129_P	134_P	0.695	0.98
371_L	378_T	0.695	0.98
132_F	139_W	0.694	0.98
142_Q	169_S	0.690	0.98
582_S	586_Q	0.688	0.98
539_I	543_I	0.685	0.98
114_A	132_F	0.685	0.98
310_R	314_S	0.683	0.98
290_S	294_G	0.683	0.98
371_L	374_S	0.682	0.98
70_K	181_L	0.681	0.98
173_K	176_S	0.679	0.98
139_W	167_T	0.679	0.98
480_L	529_A	0.678	0.98
439_G	442_E	0.677	0.97
35_F	286_I	0.676	0.97
473_S	477_T	0.676	0.97
435_S	579_T	0.673	0.97
637_I	645_A	0.673	0.97
494_A	523_V	0.673	0.97
451_Q	563_I	0.673	0.97
589_N	593_E	0.673	0.97
61_S	64_Q	0.672	0.97
228_W	233_Y	0.672	0.97
538_E	541_R	0.672	0.97
286_I	290_S	0.671	0.97
406_S	413_M	0.671	0.97
433_Q	577_M	0.671	0.97
13_I	309_L	0.669	0.97
316_S	350_L	0.668	0.97
622_D	626_S	0.666	0.97
22_L	26_I	0.665	0.97
489_Q	524_Q	0.665	0.97
37_Y	276_S	0.664	0.97
96_E	100_Q	0.663	0.97
302_I	309_L	0.662	0.97
140_Y	167_T	0.662	0.97
102_T	111_I	0.660	0.97
142_Q	151_V	0.659	0.97
479_I	482_V	0.659	0.97
640_S	643_T	0.658	0.97
192_S	205_I	0.658	0.97
592_V	595_L	0.658	0.97
91_K	94_L	0.658	0.97
135_T	139_W	0.657	0.97
427_I	581_I	0.657	0.97
413_M	420_V	0.657	0.97
357_I	360_S	0.656	0.97
380_K	383_E	0.656	0.97
289_V	296_I	0.654	0.97
355_G	358_Q	0.651	0.97
300_Y	303_R	0.651	0.97
135_T	138_D	0.649	0.97
600_Q	603_S	0.649	0.97
36_S	294_G	0.649	0.97
568_A	572_K	0.649	0.97
48_L	276_S	0.648	0.97
445_V	564_T	0.648	0.97
172_L	177_G	0.646	0.97
25_L	298_I	0.646	0.97
346_M	351_R	0.644	0.97
256_N	259_T	0.643	0.97
423_A	587_N	0.643	0.97
540_V	544_S	0.641	0.97
24_V	28_P	0.641	0.97
56_V	254_T	0.641	0.97
219_K	223_T	0.640	0.96
110_A	114_A	0.640	0.96
352_S	355_G	0.640	0.96
476_I	529_A	0.639	0.96
378_T	399_Q	0.636	0.96
604_S	607_E	0.635	0.96
49_I	53_K	0.635	0.96
123_Y	126_S	0.634	0.96
407_S	606_V	0.634	0.96
136_G	139_W	0.633	0.96
60_N	254_T	0.633	0.96
147_K	171_Q	0.633	0.96
235_K	238_G	0.631	0.96
431_S	441_G	0.628	0.96
635_E	638_S	0.628	0.96
116_E	144_V	0.627	0.96
320_S	342_S	0.627	0.96
110_A	182_D	0.626	0.96
431_S	578_T	0.626	0.96
473_S	539_I	0.624	0.96
320_S	345_E	0.624	0.96
637_I	640_S	0.623	0.96
241_E	248_E	0.623	0.96
639_S	642_E	0.622	0.96
235_K	255_T	0.622	0.96
220_P	223_T	0.621	0.96
13_I	305_I	0.621	0.96
143_A	147_K	0.621	0.96
414_N	603_S	0.620	0.96
604_S	608_D	0.620	0.96
399_Q	406_S	0.620	0.96
363_N	366_S	0.620	0.96
560_G	599_S	0.619	0.96
407_S	416_G	0.619	0.96
543_I	547_L	0.618	0.96
53_K	57_E	0.617	0.96
468_G	472_K	0.617	0.96
445_V	449_V	0.615	0.96
299_L	303_R	0.614	0.96
75_D	170_K	0.614	0.96
364_V	367_S	0.613	0.96
452_M	561_L	0.613	0.96
400_S	403_L	0.612	0.95
137_R	156_Y	0.612	0.95
270_S	273_Q	0.612	0.95
426_T	584_E	0.611	0.95
153_S	158_D	0.610	0.95
405_T	601_E	0.609	0.95
334_N	340_G	0.609	0.95
402_K	605_A	0.608	0.95
488_D	526_A	0.605	0.95
111_I	181_L	0.603	0.95
169_S	182_D	0.603	0.95
437_A	440_S	0.602	0.95
344_N	351_R	0.601	0.95
18_I	23_A	0.601	0.95
133_D	140_Y	0.600	0.95
433_Q	580_Q	0.599	0.95
543_I	546_S	0.598	0.95
548_S	552_S	0.598	0.95
598_G	601_E	0.598	0.95
12_S	338_Q	0.596	0.95
25_L	291_I	0.595	0.95
205_I	263_I	0.595	0.95
92_T	95_K	0.594	0.95
325_T	351_R	0.594	0.95
534_G	537_Q	0.592	0.95
415_E	418_S	0.591	0.95
494_A	498_A	0.590	0.95
60_N	64_Q	0.590	0.95
372_T	375_A	0.590	0.95
402_K	413_M	0.590	0.95
14_S	306_T	0.589	0.94
488_D	498_A	0.588	0.94
114_A	135_T	0.588	0.94
360_S	363_N	0.587	0.94
206_T	264_A	0.585	0.94
137_R	157_T	0.583	0.94
630_Q	641_A	0.583	0.94
132_F	135_T	0.581	0.94
616_S	637_I	0.581	0.94
46_R	50_S	0.581	0.94
129_P	132_F	0.581	0.94
591_T	595_L	0.581	0.94
195_I	203_A	0.580	0.94
448_T	560_G	0.580	0.94
494_A	516_E	0.580	0.94
46_R	49_I	0.579	0.94
119_K	122_K	0.579	0.94
192_S	203_A	0.578	0.94
427_I	588_L	0.578	0.94
361_V	364_V	0.577	0.94
633_S	636_E	0.577	0.94
120_L	134_P	0.576	0.94
563_I	566_Q	0.575	0.94
416_G	594_Q	0.574	0.94
461_K	549_M	0.574	0.94
427_I	431_S	0.573	0.94
414_N	417_I	0.573	0.94
307_K	310_R	0.571	0.94
136_G	159_E	0.571	0.94
589_N	596_S	0.569	0.93
420_V	424_S	0.569	0.93
442_E	575_Y	0.569	0.93
315_T	319_I	0.568	0.93
242_Y	266_T	0.568	0.93
405_T	409_H	0.568	0.93
617_S	621_Q	0.568	0.93
156_Y	165_V	0.567	0.93
416_G	591_T	0.567	0.93
403_L	606_V	0.566	0.93
516_E	524_Q	0.566	0.93
595_L	598_G	0.566	0.93
303_R	310_R	0.564	0.93
489_Q	517_E	0.564	0.93
55_N	58_E	0.563	0.93
415_E	594_Q	0.563	0.93
192_S	214_A	0.562	0.93
470_E	543_I	0.562	0.93
606_V	610_S	0.561	0.93
59_L	195_I	0.561	0.93
221_G	224_G	0.560	0.93
134_P	139_W	0.560	0.93
411_S	416_G	0.560	0.93
268_F	271_E	0.557	0.93
546_S	549_M	0.556	0.93
536_I	546_S	0.556	0.93
341_E	344_N	0.555	0.93
413_M	602_V	0.554	0.92
435_S	582_S	0.554	0.92
410_L	602_V	0.553	0.92
412_Q	421_A	0.553	0.92
479_I	485_G	0.553	0.92
595_L	637_I	0.552	0.92
340_G	346_M	0.551	0.92
427_I	441_G	0.551	0.92
345_E	349_S	0.550	0.92
400_S	614_K	0.549	0.92
460_Q	558_K	0.549	0.92
581_I	595_L	0.547	0.92
417_I	592_V	0.546	0.92
423_A	584_E	0.546	0.92
580_Q	584_E	0.545	0.92
308_P	339_L	0.544	0.92
430_S	577_M	0.541	0.92
34_Y	37_Y	0.540	0.92
128_V	134_P	0.539	0.91
273_Q	276_S	0.538	0.91
588_L	595_L	0.538	0.91
456_D	558_K	0.538	0.91
137_R	141_K	0.537	0.91
507_Y	512_S	0.537	0.91
481_N	484_N	0.535	0.91
366_S	373_A	0.535	0.91
409_H	416_G	0.535	0.91
571_F	581_I	0.533	0.91
575_Y	579_T	0.533	0.91
255_T	258_L	0.531	0.91
503_R	518_V	0.529	0.91
317_A	320_S	0.529	0.91
66_K	69_D	0.528	0.91
68_E	72_K	0.528	0.91
451_Q	455_I	0.527	0.91
504_A	518_V	0.527	0.91
340_G	343_F	0.527	0.91
72_K	76_Y	0.527	0.91
420_V	427_I	0.526	0.90
424_S	585_L	0.526	0.90
235_K	262_K	0.526	0.90
413_M	598_G	0.525	0.90
121_Y	124_P	0.525	0.90
476_I	495_L	0.525	0.90
620_I	623_I	0.525	0.90
445_V	567_T	0.524	0.90
218_I	221_G	0.524	0.90
28_P	294_G	0.524	0.90
17_L	302_I	0.523	0.90
434_S	441_G	0.522	0.90
326_E	346_M	0.522	0.90
263_I	268_F	0.522	0.90
440_S	573_Q	0.522	0.90
120_L	124_P	0.522	0.90
639_S	643_T	0.520	0.90
300_Y	304_A	0.520	0.90
598_G	605_A	0.520	0.90
495_L	518_V	0.520	0.90
611_A	618_A	0.519	0.90
39_S	42_N	0.518	0.90
595_L	644_L	0.517	0.90
54_G	57_E	0.517	0.90
444_L	447_H	0.516	0.90
128_V	131_G	0.516	0.90
469_L	630_Q	0.515	0.89
441_G	526_A	0.514	0.89
446_E	568_A	0.514	0.89
589_N	594_Q	0.514	0.89
411_S	603_S	0.514	0.89
466_V	470_E	0.514	0.89
59_L	203_A	0.513	0.89
367_S	370_E	0.513	0.89
399_Q	409_H	0.512	0.89
574_I	578_T	0.512	0.89
26_I	291_I	0.511	0.89
367_S	378_T	0.511	0.89
584_E	588_L	0.511	0.89
128_V	133_D	0.511	0.89
413_M	427_I	0.510	0.89
599_S	603_S	0.510	0.89
223_T	226_G	0.510	0.89
402_K	405_T	0.510	0.89
356_V	360_S	0.508	0.89
42_N	46_R	0.508	0.89
597_A	600_Q	0.508	0.89
536_I	539_I	0.507	0.89
484_N	530_K	0.507	0.89
130_K	133_D	0.506	0.89
131_G	135_T	0.506	0.89
197_I	200_E	0.506	0.89
189_L	214_A	0.506	0.89
74_I	78_S	0.505	0.89
398_A	402_K	0.505	0.89
64_Q	256_N	0.504	0.88
113_A	177_G	0.503	0.88
442_E	446_E	0.503	0.88
51_S	55_N	0.502	0.88
201_G	271_E	0.501	0.88
407_S	413_M	0.500	0.88
20_A	294_G	0.500	0.88

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.4577	100	0.506	Contact Map
2ch7A	2	0.4668	100	0.588	Contact Map
1qu7A	2	0.3429	100	0.609	Contact Map
3g67A	2	0.3157	100	0.673	Contact Map
4i3mA	2	0.2221	99.9	0.794	Contact Map
3lifA	1	0.3535	99.9	0.812	Contact Map
3c8cA	2	0.352	99.9	0.818	Contact Map
3li9A	2	0.3369	99.9	0.819	Contact Map
3e4oA	2	0.3263	99.9	0.82	Contact Map
3libA	3	0.3505	99.9	0.821	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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