TLPA - BACSU - GREMLIN Contacts

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TLPA - Methyl-accepting chemotaxis protein TlpA

UniProt:	P39216	Sequences: MKKTLTTIRRSSIARRLIISFLLILIVPITALSVSAYQSAVASLDVQMTQSAKENVQILDHIIDDKISTTEKSLAYFSDWATAEKFQDKKKTELKQEFKQFIQMNDNVAAVFSSGKDGDFTRYPYADMPSDFNALERDWYKEAMANKGKTIVTEPYESISSGKMVVTIARQTVDGSGVVAIDMKIDDLVTTAKGINIGKEGYAFILSQNKKVIAYSGEKAGTELKGDWVDKLYKDKSGDFEYTYKGKKKKMAFATSQTTGWKISGTMYANEIHDAASRVLIMASIVLAIAIGAGMTAIYFVIRSITKPLRRIVASAEKISEGDLTETIEINSKDELGVLSESFNHMAHSLRSLIHGIKDSVEHVASSSEELTASADQTSRATEHITMAIEQFSNGSESQSEKIETTTEQINEMNDGLAELARAAAVITETSADSTEVSSKGETLVQKTAGQMNTIDHSVKAAEQVVKGLEIKSKDITNILRVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIESLISEIVKEIHTSLNVLQSVNKEVETGLVMTDETKQSFKHISQMTNQIASELQNMNATVEELSAGAQEISAASNDITAISKESSDGIQDIAASAEEQLASMEEISSSALTLERMSEELRDLTKQFKVDK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	662 (617)
Sequences:	7608 (6594)
Seq/√Len:	265.4

ECOLI - AER MCP3 MCP4 MCP1 MCP2
BACSU - TLPA MCPA MCPB TLPB MCPC TLPC YVAQ YOAH
HALSA - HTR4 COST HTR2 Q9HRA1 Q9HR88 Q9HRN6 Q9HP10 Q9HQX8 Q9HPA2 HTR7 Q9HS86 Q9HPQ5 HTR9 HMAT Q9HQT5 HTR1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
332_S	337_G	6.479	1.00
327_T	351_R	4.297	1.00
16_R	334_D	3.879	1.00
318_K	323_D	3.444	1.00
334_D	337_G	3.371	1.00
34_V	38_Q	3.353	1.00
14_A	303_R	3.330	1.00
316_A	346_M	2.758	1.00
112_F	180_A	2.714	1.00
471_I	474_K	2.654	1.00
498_A	519_R	2.646	1.00
317_E	338_V	2.553	1.00
200_E	271_E	2.525	1.00
465_V	546_S	2.480	1.00
455_I	560_G	2.408	1.00
481_R	485_G	2.383	1.00
302_I	306_T	2.357	1.00
248_K	269_A	2.352	1.00
285_I	289_I	2.345	1.00
327_T	348_H	2.308	1.00
327_T	344_N	2.287	1.00
551_Q	555_K	2.285	1.00
204_F	264_S	2.279	1.00
477_T	540_V	2.245	1.00
312_I	316_A	2.239	1.00
12_S	15_R	2.218	1.00
281_I	285_I	2.192	1.00
472_K	542_E	2.170	1.00
255_T	262_K	2.158	1.00
303_R	307_K	2.128	1.00
167_T	182_D	2.128	1.00
520_K	523_V	2.122	1.00
525_S	529_A	2.112	1.00
468_G	542_E	2.107	1.00
498_A	516_E	2.090	1.00
479_I	535_L	2.083	1.00
472_K	538_E	2.078	1.00
427_I	585_L	2.053	1.00
197_I	201_G	2.043	1.00
469_L	546_S	2.037	1.00
319_I	346_M	2.031	1.00
441_G	571_F	2.019	1.00
441_G	574_I	2.017	1.00
516_E	519_R	2.002	1.00
141_K	145_A	1.998	1.00
565_D	569_Q	1.995	1.00
36_A	283_A	1.994	1.00
473_S	543_I	1.973	1.00
622_D	625_A	1.961	1.00
419_E	422_R	1.959	1.00
562_V	566_E	1.946	1.00
142_E	145_A	1.945	1.00
475_D	478_N	1.944	1.00
230_D	234_K	1.939	1.00
470_E	547_L	1.935	1.00
344_N	347_A	1.935	1.00
115_G	119_D	1.935	1.00
440_K	443_T	1.919	1.00
318_K	326_E	1.901	1.00
99_K	103_Q	1.898	1.00
555_K	558_E	1.892	1.00
478_N	481_R	1.870	1.00
590_A	593_E	1.855	1.00
443_T	447_K	1.840	1.00
482_V	528_S	1.840	1.00
156_Y	167_T	1.839	1.00
316_A	343_F	1.835	1.00
298_I	302_I	1.831	1.00
313_V	338_V	1.829	1.00
313_V	342_S	1.828	1.00
559_T	562_V	1.826	1.00
338_V	341_E	1.819	1.00
366_S	370_E	1.816	1.00
484_N	529_A	1.788	1.00
405_T	408_E	1.782	1.00
449_A	568_K	1.765	1.00
202_Y	216_S	1.759	1.00
369_E	373_A	1.725	1.00
436_E	440_K	1.718	1.00
615_E	618_D	1.718	1.00
447_K	450_G	1.711	1.00
198_G	201_G	1.710	1.00
558_E	562_V	1.704	1.00
533_E	537_S	1.703	1.00
448_T	567_T	1.701	1.00
466_V	546_S	1.700	1.00
466_V	547_L	1.698	1.00
316_A	339_L	1.698	1.00
238_G	253_F	1.682	1.00
437_V	573_H	1.681	1.00
158_S	161_S	1.680	1.00
573_H	576_Q	1.672	1.00
611_A	615_E	1.645	1.00
555_K	559_T	1.641	1.00
607_N	611_A	1.633	1.00
429_E	433_D	1.629	1.00
133_N	136_E	1.627	1.00
33_S	37_Y	1.620	1.00
628_E	632_A	1.618	1.00
190_T	193_K	1.611	1.00
465_V	545_T	1.611	1.00
278_R	282_M	1.604	1.00
330_I	344_N	1.597	1.00
641_A	644_L	1.596	1.00
154_E	209_N	1.591	1.00
450_G	454_T	1.580	1.00
378_T	382_T	1.580	1.00
471_I	475_D	1.557	1.00
163_K	186_D	1.554	1.00
601_E	604_A	1.553	1.00
40_A	279_V	1.546	1.00
202_Y	215_Y	1.540	1.00
33_S	287_L	1.538	1.00
432_A	436_E	1.529	1.00
108_V	181_I	1.525	1.00
571_F	574_I	1.518	1.00
348_H	352_S	1.511	1.00
156_Y	182_D	1.508	1.00
401_E	404_E	1.504	1.00
468_G	471_I	1.497	1.00
618_D	622_D	1.484	1.00
351_R	355_H	1.483	1.00
227_D	230_D	1.481	1.00
317_E	342_S	1.479	1.00
469_L	539_I	1.478	1.00
309_L	339_L	1.473	1.00
312_I	339_L	1.465	1.00
64_D	68_S	1.464	1.00
339_L	343_F	1.459	1.00
629_E	632_A	1.457	1.00
611_A	614_K	1.453	1.00
472_K	475_D	1.449	1.00
28_P	290_A	1.445	1.00
198_G	271_E	1.444	1.00
226_G	230_D	1.440	1.00
152_V	168_I	1.440	1.00
187_D	190_T	1.438	1.00
148_G	173_V	1.438	1.00
155_P	164_M	1.437	1.00
316_A	342_S	1.435	1.00
366_S	369_E	1.433	1.00
319_I	347_A	1.427	1.00
413_M	599_A	1.424	1.00
203_A	265_G	1.421	1.00
452_M	560_G	1.420	1.00
251_M	264_S	1.419	1.00
593_E	597_A	1.419	1.00
425_A	429_E	1.418	1.00
25_L	28_P	1.416	1.00
618_D	621_Q	1.415	1.00
113_S	172_T	1.408	1.00
327_T	347_A	1.404	1.00
452_M	455_I	1.403	1.00
594_E	597_A	1.399	1.00
317_E	345_H	1.394	1.00
373_A	377_Q	1.388	1.00
247_K	268_Y	1.387	1.00
211_K	223_E	1.387	1.00
527_D	531_E	1.386	1.00
461_A	464_Q	1.386	1.00
411_N	415_D	1.381	1.00
600_Q	604_A	1.375	1.00
566_E	569_Q	1.374	1.00
433_D	436_E	1.370	1.00
140_Y	144_M	1.370	1.00
544_H	548_N	1.358	1.00
530_K	534_S	1.357	1.00
289_I	293_A	1.355	1.00
95_K	99_K	1.348	1.00
118_G	135_L	1.348	1.00
292_G	296_T	1.344	1.00
22_L	295_M	1.344	1.00
635_E	639_S	1.344	1.00
402_K	608_D	1.343	1.00
458_S	552_S	1.341	1.00
52_A	56_V	1.340	1.00
495_L	503_R	1.330	1.00
138_D	142_E	1.328	1.00
429_E	432_A	1.326	1.00
527_D	530_K	1.324	1.00
580_Q	583_S	1.318	1.00
453_N	457_H	1.305	1.00
190_T	194_G	1.303	1.00
280_L	284_S	1.301	1.00
632_A	635_E	1.300	1.00
485_G	488_D	1.297	1.00
241_E	269_A	1.297	1.00
376_D	380_R	1.296	1.00
408_E	412_E	1.296	1.00
608_D	611_A	1.294	1.00
330_I	334_D	1.284	1.00
625_A	628_E	1.281	1.00
243_T	248_K	1.280	1.00
143_A	169_A	1.280	1.00
583_S	587_N	1.279	1.00
446_Q	450_G	1.278	1.00
47_Q	51_S	1.276	1.00
398_S	401_E	1.274	1.00
40_A	44_L	1.269	1.00
244_Y	249_K	1.268	1.00
459_V	557_V	1.266	1.00
284_S	288_A	1.258	1.00
523_V	527_D	1.257	1.00
494_A	519_R	1.253	1.00
202_Y	266_T	1.251	1.00
13_I	336_L	1.249	1.00
14_A	18_I	1.246	1.00
625_A	629_E	1.242	1.00
242_Y	249_K	1.238	1.00
29_I	32_L	1.238	1.00
583_S	586_Q	1.236	1.00
151_I	169_A	1.236	1.00
422_R	426_V	1.234	1.00
576_Q	580_Q	1.233	1.00
143_A	178_V	1.231	1.00
249_K	268_Y	1.227	1.00
451_Q	559_T	1.227	1.00
370_E	373_A	1.227	1.00
379_S	382_T	1.222	1.00
443_T	446_Q	1.221	1.00
330_I	340_S	1.221	1.00
426_V	429_E	1.218	1.00
590_A	594_E	1.214	1.00
460_K	554_N	1.210	1.00
323_D	326_E	1.207	1.00
11_S	19_I	1.207	1.00
304_S	307_K	1.202	1.00
232_L	264_S	1.200	1.00
315_S	328_I	1.198	1.00
569_Q	572_K	1.198	1.00
412_E	415_D	1.191	1.00
491_N	519_R	1.191	1.00
282_M	285_I	1.189	1.00
269_A	273_H	1.188	1.00
519_R	523_V	1.188	1.00
312_I	340_S	1.187	1.00
484_N	533_E	1.185	1.00
100_Q	103_Q	1.185	1.00
466_V	550_L	1.183	1.00
401_E	405_T	1.179	1.00
324_L	354_I	1.178	1.00
312_I	343_F	1.176	1.00
621_Q	625_A	1.175	1.00
71_E	75_A	1.175	1.00
439_S	443_T	1.168	1.00
453_N	565_D	1.168	1.00
66_K	70_T	1.154	1.00
38_Q	42_A	1.153	1.00
548_N	551_Q	1.151	1.00
418_A	422_R	1.151	1.00
21_F	298_I	1.148	1.00
91_K	95_K	1.148	1.00
438_S	441_G	1.147	1.00
37_Y	280_L	1.144	1.00
457_H	461_A	1.142	1.00
35_S	39_S	1.141	1.00
186_D	190_T	1.140	1.00
552_S	555_K	1.140	1.00
537_S	541_K	1.140	1.00
436_E	439_S	1.138	1.00
41_V	45_D	1.138	1.00
467_K	471_I	1.137	1.00
11_S	15_R	1.137	1.00
614_K	618_D	1.136	1.00
199_K	271_E	1.135	1.00
231_K	235_D	1.133	1.00
457_H	460_K	1.133	1.00
526_A	530_K	1.129	1.00
318_K	346_M	1.128	1.00
319_I	343_F	1.126	1.00
71_E	152_V	1.123	1.00
450_G	453_N	1.123	1.00
524_Q	531_E	1.121	1.00
569_Q	573_H	1.120	1.00
74_L	170_R	1.120	1.00
475_D	531_E	1.117	1.00
548_N	552_S	1.117	1.00
530_K	533_E	1.117	1.00
442_E	572_K	1.115	1.00
120_F	123_Y	1.112	1.00
479_I	536_I	1.110	1.00
45_D	49_T	1.108	1.00
413_M	595_L	1.107	1.00
319_I	324_L	1.106	1.00
352_S	356_G	1.102	1.00
313_V	317_E	1.091	1.00
463_E	550_L	1.090	1.00
281_I	284_S	1.090	1.00
207_S	211_K	1.089	1.00
18_I	22_L	1.084	1.00
295_M	299_Y	1.080	1.00
141_K	144_M	1.078	1.00
155_P	207_S	1.075	1.00
409_Q	412_E	1.074	1.00
204_F	215_Y	1.074	1.00
534_S	538_E	1.074	1.00
464_Q	468_G	1.073	1.00
169_A	178_V	1.072	1.00
319_I	350_L	1.066	1.00
277_S	280_L	1.065	1.00
460_K	464_Q	1.064	1.00
75_A	150_T	1.063	1.00
333_K	337_G	1.062	1.00
507_Y	518_V	1.061	1.00
328_I	344_N	1.060	1.00
465_V	549_V	1.058	1.00
96_Q	99_K	1.054	1.00
361_V	368_S	1.054	1.00
321_E	349_S	1.053	1.00
604_A	607_N	1.053	1.00
322_G	339_L	1.052	1.00
438_S	575_S	1.051	1.00
277_S	281_I	1.050	1.00
413_M	416_G	1.048	1.00
572_K	576_Q	1.044	1.00
25_L	294_G	1.036	1.00
587_N	590_A	1.034	1.00
474_K	544_H	1.033	1.00
112_F	182_D	1.032	1.00
72_K	75_A	1.031	1.00
315_S	343_F	1.025	1.00
114_S	134_A	1.023	1.00
541_K	545_T	1.021	1.00
560_G	567_T	1.021	1.00
343_F	347_A	1.021	1.00
447_K	563_M	1.020	1.00
153_T	156_Y	1.020	1.00
324_L	350_L	1.018	1.00
562_V	565_D	1.018	1.00
358_K	362_E	1.015	1.00
357_I	364_V	1.013	1.00
294_G	298_I	1.010	1.00
411_N	414_N	1.009	1.00
314_A	317_E	1.007	1.00
455_I	557_V	1.004	1.00
33_S	283_A	1.004	1.00
488_D	499_I	1.004	1.00
17_L	21_F	1.001	1.00
524_Q	527_D	1.001	1.00
619_G	622_D	0.998	1.00
20_S	301_V	0.998	1.00
579_N	583_S	0.997	1.00
373_A	376_D	0.997	1.00
136_E	141_K	0.996	1.00
137_R	159_I	0.993	1.00
249_K	266_T	0.991	1.00
316_A	319_I	0.988	1.00
311_R	314_A	0.987	1.00
636_E	639_S	0.987	1.00
26_I	30_T	0.985	1.00
343_F	346_M	0.984	1.00
464_Q	467_K	0.983	1.00
30_T	34_V	0.983	1.00
302_I	305_I	0.981	1.00
456_D	561_L	0.980	1.00
469_L	543_I	0.980	1.00
74_L	181_I	0.980	1.00
339_L	346_M	0.979	1.00
135_L	140_Y	0.979	1.00
463_E	554_N	0.979	1.00
479_I	528_S	0.979	1.00
347_A	351_R	0.978	1.00
424_A	427_I	0.977	1.00
536_I	540_V	0.977	1.00
399_Q	403_I	0.975	1.00
139_W	156_Y	0.975	1.00
308_P	332_S	0.974	1.00
29_I	287_L	0.972	1.00
16_R	304_S	0.969	1.00
340_S	344_N	0.969	1.00
231_K	236_K	0.968	1.00
130_S	134_A	0.967	1.00
462_A	553_V	0.965	1.00
313_V	339_L	0.965	1.00
421_A	424_A	0.964	1.00
322_G	346_M	0.963	1.00
288_A	292_G	0.961	1.00
399_Q	613_S	0.960	1.00
459_V	550_L	0.958	1.00
492_L	499_I	0.958	1.00
586_Q	590_A	0.957	1.00
543_I	546_S	0.957	1.00
122_R	125_Y	0.956	1.00
452_M	564_T	0.956	1.00
377_Q	380_R	0.955	1.00
230_D	233_Y	0.955	1.00
468_G	545_T	0.952	1.00
311_R	329_E	0.949	1.00
479_I	529_A	0.948	1.00
587_N	591_T	0.948	1.00
346_M	350_L	0.942	1.00
375_A	382_T	0.938	1.00
612_I	616_S	0.936	1.00
133_N	137_R	0.934	1.00
458_S	556_E	0.933	1.00
150_T	170_R	0.931	1.00
247_K	270_N	0.930	1.00
409_Q	413_M	0.926	1.00
139_W	167_T	0.924	1.00
359_D	363_H	0.921	1.00
299_Y	303_R	0.917	1.00
359_D	362_E	0.916	1.00
308_P	336_L	0.914	1.00
167_T	180_A	0.913	1.00
328_I	340_S	0.913	1.00
540_V	547_L	0.911	1.00
318_K	321_E	0.911	1.00
70_T	73_S	0.910	1.00
137_R	158_S	0.908	1.00
140_Y	178_V	0.908	1.00
68_S	71_E	0.907	1.00
231_K	234_K	0.907	1.00
597_A	601_E	0.906	1.00
467_K	551_Q	0.906	1.00
330_I	337_G	0.906	1.00
64_D	258_T	0.906	1.00
158_S	182_D	0.905	1.00
556_E	559_T	0.905	1.00
415_D	419_E	0.904	1.00
362_E	366_S	0.903	1.00
425_A	593_E	0.902	1.00
404_E	408_E	0.901	1.00
604_A	608_D	0.897	1.00
250_K	269_A	0.896	1.00
590_A	597_A	0.895	1.00
368_S	371_L	0.895	1.00
119_D	133_N	0.894	1.00
375_A	379_S	0.894	1.00
479_I	525_S	0.894	1.00
32_L	36_A	0.891	1.00
148_G	171_Q	0.890	1.00
355_H	359_D	0.889	1.00
406_T	605_A	0.888	1.00
412_E	598_G	0.884	1.00
158_S	165_V	0.884	1.00
157_E	164_M	0.884	1.00
60_D	256_S	0.883	1.00
274_D	278_R	0.882	1.00
632_A	636_E	0.881	1.00
229_V	232_L	0.880	1.00
139_W	182_D	0.879	1.00
92_T	96_Q	0.879	1.00
494_A	518_V	0.875	1.00
445_V	448_T	0.874	1.00
412_E	416_G	0.873	1.00
516_E	520_K	0.873	1.00
531_E	534_S	0.873	1.00
150_T	168_I	0.873	1.00
438_S	442_E	0.869	1.00
623_I	626_S	0.869	1.00
417_L	592_V	0.869	1.00
56_V	265_G	0.867	1.00
445_V	564_T	0.865	1.00
56_V	60_D	0.863	1.00
69_T	72_K	0.862	1.00
417_L	595_L	0.862	1.00
78_S	170_R	0.861	1.00
353_L	357_I	0.859	1.00
122_R	126_A	0.858	1.00
546_S	550_L	0.856	1.00
345_H	348_H	0.852	1.00
435_T	439_S	0.852	1.00
256_S	259_T	0.850	1.00
463_E	551_Q	0.849	1.00
622_D	626_S	0.848	1.00
462_A	550_L	0.845	1.00
538_E	542_E	0.843	0.99
296_T	300_F	0.843	0.99
431_S	578_T	0.843	0.99
311_R	315_S	0.842	0.99
522_A	525_S	0.840	0.99
462_A	466_V	0.838	0.99
242_Y	251_M	0.835	0.99
227_D	231_K	0.834	0.99
22_L	26_I	0.834	0.99
447_K	566_E	0.834	0.99
630_Q	637_I	0.833	0.99
352_S	355_H	0.828	0.99
637_I	644_L	0.827	0.99
11_S	333_K	0.827	0.99
132_F	137_R	0.824	0.99
163_K	184_K	0.823	0.99
315_S	326_E	0.823	0.99
434_S	578_T	0.822	0.99
454_T	556_E	0.820	0.99
518_V	524_Q	0.820	0.99
444_L	566_E	0.818	0.99
623_I	630_Q	0.818	0.99
330_I	341_E	0.816	0.99
337_G	340_S	0.815	0.99
420_L	578_T	0.814	0.99
199_K	274_D	0.813	0.99
420_L	592_V	0.813	0.99
637_I	640_S	0.812	0.99
110_A	124_P	0.812	0.99
423_A	587_N	0.810	0.99
435_T	582_A	0.810	0.99
153_T	169_A	0.809	0.99
364_V	367_S	0.808	0.99
51_S	54_E	0.807	0.99
135_L	138_D	0.802	0.99
610_T	614_K	0.802	0.99
114_S	120_F	0.799	0.99
413_M	602_I	0.797	0.99
445_V	571_F	0.796	0.99
553_V	560_G	0.796	0.99
278_R	281_I	0.795	0.99
428_T	432_A	0.795	0.99
75_A	170_R	0.794	0.99
279_V	283_A	0.793	0.99
204_F	266_T	0.792	0.99
80_W	83_A	0.791	0.99
153_T	167_T	0.791	0.99
368_S	375_A	0.790	0.99
448_T	452_M	0.790	0.99
53_K	57_Q	0.789	0.99
45_D	273_H	0.788	0.99
289_I	296_T	0.788	0.99
177_G	180_A	0.786	0.99
470_E	544_H	0.786	0.99
458_S	461_A	0.784	0.99
81_A	85_K	0.784	0.99
65_D	68_S	0.781	0.99
473_S	479_I	0.781	0.99
416_G	598_G	0.780	0.99
611_A	618_D	0.780	0.99
154_E	207_S	0.780	0.99
564_T	567_T	0.779	0.99
634_M	637_I	0.779	0.99
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478_N	482_V	0.777	0.99
479_I	482_V	0.776	0.99
306_T	310_R	0.775	0.99
344_N	348_H	0.775	0.99
439_S	442_E	0.773	0.99
26_I	291_I	0.772	0.99
211_K	214_A	0.771	0.99
131_D	137_R	0.769	0.99
492_L	520_K	0.768	0.99
445_V	567_T	0.767	0.99
541_K	544_H	0.765	0.99
308_P	337_G	0.765	0.99
451_Q	454_T	0.764	0.99
488_D	492_L	0.763	0.99
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434_S	441_G	0.760	0.99
403_I	609_I	0.760	0.99
114_S	140_Y	0.760	0.99
475_D	538_E	0.759	0.99
377_Q	381_A	0.759	0.99
316_A	350_L	0.758	0.99
310_R	313_V	0.758	0.99
448_T	455_I	0.756	0.99
355_H	358_K	0.755	0.99
408_E	411_N	0.755	0.99
399_Q	413_M	0.754	0.99
402_K	605_A	0.752	0.99
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356_G	359_D	0.751	0.99
290_A	294_G	0.751	0.99
410_I	606_S	0.751	0.99
454_T	457_H	0.749	0.99
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637_I	641_A	0.746	0.99
13_I	335_E	0.746	0.99
437_V	440_K	0.745	0.99
463_E	546_S	0.744	0.99
470_E	474_K	0.743	0.99
336_L	340_S	0.738	0.99
411_N	603_S	0.737	0.99
525_S	535_L	0.735	0.99
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138_D	141_K	0.733	0.99
447_K	559_T	0.732	0.99
102_I	111_V	0.732	0.99
71_E	150_T	0.732	0.99
212_V	215_Y	0.731	0.99
315_S	319_I	0.731	0.99
302_I	309_L	0.730	0.99
208_Q	260_G	0.729	0.99
588_M	595_L	0.728	0.99
448_T	564_T	0.727	0.99
365_A	369_E	0.725	0.98
616_S	619_G	0.725	0.98
114_S	139_W	0.725	0.98
50_Q	54_E	0.724	0.98
73_S	76_Y	0.724	0.98
543_I	547_L	0.723	0.98
371_L	375_A	0.723	0.98
349_S	352_S	0.723	0.98
347_A	350_L	0.720	0.98
110_A	182_D	0.720	0.98
81_A	84_E	0.720	0.98
403_I	410_I	0.719	0.98
317_E	321_E	0.717	0.98
24_I	28_P	0.717	0.98
232_L	262_K	0.716	0.98
130_S	133_N	0.716	0.98
303_R	310_R	0.714	0.98
168_I	183_M	0.713	0.98
371_L	374_S	0.712	0.98
539_I	543_I	0.711	0.98
346_M	349_S	0.711	0.98
307_K	310_R	0.711	0.98
374_S	378_T	0.711	0.98
371_L	382_T	0.711	0.98
462_A	549_V	0.710	0.98
560_G	599_A	0.709	0.98
613_S	617_S	0.708	0.98
228_W	233_Y	0.707	0.98
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93_E	96_Q	0.702	0.98
36_A	279_V	0.701	0.98
13_I	305_I	0.700	0.98
143_A	147_K	0.700	0.98
494_A	498_A	0.700	0.98
469_L	479_I	0.699	0.98
410_I	417_L	0.697	0.98
491_N	498_A	0.696	0.98
413_M	598_G	0.696	0.98
399_Q	406_T	0.694	0.98
66_K	69_T	0.693	0.98
16_R	332_S	0.693	0.98
165_V	182_D	0.693	0.98
28_P	294_G	0.693	0.98
12_S	338_V	0.693	0.98
409_Q	416_G	0.692	0.98
630_Q	644_L	0.691	0.98
61_H	64_D	0.690	0.98
616_S	637_I	0.690	0.98
120_F	134_A	0.687	0.98
68_S	72_K	0.686	0.98
37_Y	41_V	0.685	0.98
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441_G	445_V	0.684	0.98
169_A	180_A	0.683	0.98
14_A	306_T	0.681	0.98
564_T	574_I	0.680	0.98
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398_S	402_K	0.678	0.98
361_V	364_V	0.677	0.98
620_I	623_I	0.676	0.98
300_F	303_R	0.676	0.98
442_E	446_Q	0.675	0.98
413_M	420_L	0.674	0.98
221_G	225_K	0.674	0.98
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432_A	586_Q	0.673	0.98
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431_S	441_G	0.671	0.97
545_T	548_N	0.670	0.97
410_I	413_M	0.670	0.97
480_L	532_I	0.670	0.97
638_S	642_L	0.670	0.97
473_S	477_T	0.670	0.97
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534_S	537_S	0.668	0.97
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320_S	345_H	0.666	0.97
427_I	434_S	0.665	0.97
192_A	203_A	0.665	0.97
59_L	62_I	0.664	0.97
157_E	162_G	0.663	0.97
142_E	169_A	0.663	0.97
132_F	135_L	0.663	0.97
536_I	539_I	0.663	0.97
196_N	201_G	0.662	0.97
580_Q	584_E	0.662	0.97
256_S	260_G	0.661	0.97
34_V	37_Y	0.661	0.97
229_V	233_Y	0.661	0.97
36_A	40_A	0.660	0.97
325_T	351_R	0.658	0.97
38_Q	41_V	0.658	0.97
606_S	609_I	0.657	0.97
553_V	557_V	0.657	0.97
121_T	124_P	0.657	0.97
114_S	124_P	0.655	0.97
405_T	601_E	0.655	0.97
445_V	449_A	0.654	0.97
626_S	629_E	0.654	0.97
334_D	340_S	0.652	0.97
582_A	586_Q	0.651	0.97
363_H	366_S	0.650	0.97
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232_L	253_F	0.650	0.97
407_T	412_E	0.648	0.97
482_V	522_A	0.647	0.97
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400_S	403_I	0.644	0.97
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617_S	621_Q	0.643	0.97
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568_K	572_K	0.642	0.97
49_T	53_K	0.642	0.97
575_S	579_N	0.642	0.97
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494_A	516_E	0.638	0.97
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206_L	264_S	0.633	0.96
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415_D	418_A	0.630	0.96
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13_I	309_L	0.629	0.96
114_S	132_F	0.629	0.96
235_D	255_T	0.629	0.96
111_V	181_I	0.629	0.96
494_A	523_V	0.629	0.96
306_T	309_L	0.628	0.96
118_G	121_T	0.626	0.96
540_V	544_H	0.626	0.96
142_E	151_I	0.625	0.96
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317_E	320_S	0.625	0.96
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195_I	203_A	0.623	0.96
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633_S	637_I	0.618	0.96
310_R	314_A	0.618	0.96
115_G	118_G	0.618	0.96
420_L	424_A	0.616	0.96
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480_L	484_N	0.611	0.96
357_I	360_S	0.611	0.96
439_S	579_N	0.608	0.96
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172_T	177_G	0.608	0.96
557_V	560_G	0.606	0.95
480_L	533_E	0.604	0.95
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92_T	95_K	0.604	0.95
631_L	635_E	0.601	0.95
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143_A	148_G	0.598	0.95
594_E	598_G	0.597	0.95
617_S	620_I	0.597	0.95
488_D	526_A	0.597	0.95
630_Q	634_M	0.595	0.95
460_K	558_E	0.594	0.95
400_S	408_E	0.593	0.95
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546_S	553_V	0.590	0.95
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114_S	180_A	0.589	0.95
276_A	280_L	0.588	0.95
59_L	195_I	0.588	0.95
300_F	304_S	0.587	0.95
200_E	268_Y	0.586	0.95
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132_F	139_W	0.582	0.94
618_D	625_A	0.581	0.94
251_M	266_T	0.580	0.94
119_D	126_A	0.580	0.94
560_G	571_F	0.579	0.94
313_V	336_L	0.579	0.94
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324_L	346_M	0.578	0.94
177_G	182_D	0.578	0.94
452_M	561_L	0.577	0.94
272_I	276_A	0.577	0.94
119_D	123_Y	0.577	0.94
119_D	122_R	0.576	0.94
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137_R	141_K	0.573	0.94
424_A	588_M	0.572	0.94
441_G	560_G	0.570	0.94
54_E	57_Q	0.570	0.94
96_Q	100_Q	0.569	0.94
366_S	373_A	0.569	0.94
603_S	607_N	0.569	0.94
228_W	232_L	0.568	0.94
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416_G	588_M	0.567	0.94
433_D	437_V	0.567	0.94
414_N	603_S	0.566	0.94
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571_F	578_T	0.566	0.94
64_D	256_S	0.565	0.93
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197_I	265_G	0.563	0.93
67_I	70_T	0.563	0.93
131_D	134_A	0.563	0.93
99_K	102_I	0.562	0.93
630_Q	633_S	0.561	0.93
400_S	614_K	0.560	0.93
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318_K	349_S	0.557	0.93
553_V	581_I	0.556	0.93
372_T	376_D	0.555	0.93
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100_Q	104_M	0.555	0.93
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434_S	445_V	0.554	0.93
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574_I	577_M	0.552	0.93
563_M	566_E	0.552	0.93
189_V	193_K	0.551	0.93
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414_N	417_L	0.551	0.93
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546_S	549_V	0.550	0.93
273_H	276_A	0.550	0.93
411_N	416_G	0.549	0.92
491_N	494_A	0.549	0.92
375_A	378_T	0.549	0.92
346_M	351_R	0.548	0.92
564_T	568_K	0.547	0.92
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404_E	407_T	0.546	0.92
407_T	416_G	0.545	0.92
484_N	530_K	0.545	0.92
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630_Q	641_A	0.544	0.92
341_E	344_N	0.541	0.92
577_M	580_Q	0.541	0.92
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414_N	599_A	0.539	0.92
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444_L	447_K	0.537	0.92
451_Q	563_M	0.536	0.92
120_F	124_P	0.536	0.92
21_F	24_I	0.535	0.92
538_E	541_K	0.535	0.92
437_V	441_G	0.534	0.91
434_S	553_V	0.534	0.91
634_M	644_L	0.534	0.91
413_M	590_A	0.534	0.91
409_Q	598_G	0.533	0.91
132_F	136_E	0.533	0.91
286_V	290_A	0.533	0.91
129_P	133_N	0.532	0.91
406_T	606_S	0.532	0.91
489_Q	517_E	0.532	0.91
420_L	595_L	0.532	0.91
29_I	294_G	0.531	0.91
124_P	127_D	0.531	0.91
60_D	254_A	0.531	0.91
14_A	310_R	0.530	0.91
426_V	584_E	0.530	0.91
438_S	455_I	0.528	0.91
623_I	637_I	0.527	0.91
554_N	558_E	0.527	0.91
627_A	630_Q	0.527	0.91
74_L	78_S	0.526	0.91
536_I	546_S	0.525	0.91
252_A	255_T	0.525	0.91
451_Q	556_E	0.524	0.91
134_A	140_Y	0.522	0.91
421_A	596_S	0.521	0.90
356_G	360_S	0.520	0.90
47_Q	275_A	0.519	0.90
47_Q	50_Q	0.518	0.90
472_K	535_L	0.518	0.90
448_T	518_V	0.518	0.90
342_S	347_A	0.517	0.90
232_L	235_D	0.517	0.90
113_S	177_G	0.517	0.90
367_S	378_T	0.517	0.90
91_K	94_L	0.516	0.90
438_S	578_T	0.515	0.90
41_V	277_S	0.515	0.90
455_I	459_V	0.515	0.90
476_I	536_I	0.515	0.90
306_T	313_V	0.514	0.90
407_T	413_M	0.514	0.90
434_S	437_V	0.513	0.90
97_E	100_Q	0.513	0.90
147_K	171_Q	0.512	0.90
454_T	458_S	0.512	0.90
589_N	593_E	0.512	0.90
123_Y	127_D	0.512	0.90
456_D	558_E	0.512	0.90
219_K	222_T	0.512	0.90
461_A	549_V	0.511	0.90
326_E	346_M	0.510	0.89
232_L	238_G	0.510	0.89
421_A	589_N	0.509	0.89
427_I	431_S	0.509	0.89
201_G	271_E	0.508	0.89
213_I	261_W	0.508	0.89
263_I	268_Y	0.507	0.89
115_G	121_T	0.507	0.89
14_A	302_I	0.506	0.89
270_N	277_S	0.506	0.89
25_L	291_I	0.506	0.89
455_I	553_V	0.505	0.89
122_R	127_D	0.505	0.89
409_Q	434_S	0.505	0.89
345_H	349_S	0.504	0.89
360_S	363_H	0.503	0.89
136_E	159_I	0.503	0.89
371_L	379_S	0.502	0.89
140_Y	182_D	0.501	0.89
623_I	631_L	0.500	0.89
420_L	427_I	0.500	0.89
312_I	315_S	0.500	0.89

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.4577	100	0.513	Contact Map
2ch7A	2	0.4668	100	0.588	Contact Map
1qu7A	2	0.3414	100	0.621	Contact Map
3g67A	2	0.3157	100	0.671	Contact Map
4i3mA	2	0.2221	99.9	0.795	Contact Map
3lifA	1	0.355	99.9	0.814	Contact Map
3lidA	2	0.3686	99.9	0.825	Contact Map
3c8cA	2	0.3505	99.9	0.826	Contact Map
3li9A	2	0.3369	99.9	0.826	Contact Map
3libA	3	0.3505	99.9	0.827	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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