MCPB - BACSU - GREMLIN Contacts

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MCPB - Methyl-accepting chemotaxis protein McpB

UniProt:	P39215	Sequences: MKTFINWLKKPSISKKLIVSFIAILIIPILILEFSSYRSASGKLDQEIMGNAKNSVDTFNTTVTNDLGEKAKAVTFFSESLKRSAFKGKSNQEEIKAKFSQYVSINQGVARIYGGADNGTYVQAPKEKLPEGYDPRQRPWYQDAMKAGGEIVVTDPYVAASDGSMVITIAQELKDGSGVVAMDITIDKLLEQMKQIKVGKEGYAFIATKNKTYVAHKNHKAGEKLSGDWVAKMYANDSGELQYTLNNEDKKMTYTTNELTGWKIAGTMYMDEIKDASKSVLTTGMIVLIASIVAGGILILFIVRSITKPLKRLVQSSKTISRGDLTETIEIHSKDELGELGESFNEMGQSLRSLISAIQDSVNNVAASSEQLTASAGQTSKATEHITMAIEQFSNGNEEQSEKVESSSHQLNLMNEGLQQVSQTSSDITKASIQSTEIAGTGEKFVQQTVGQMNSINQSVQQAEAVVKGLEGKSKDITSILRVINGIADQTNLLALNAAIEAARAGESGRGFSVVAEEVRKLAVQSADSAKEIEKLIQEIVAEIDTSLHMFKEVNQEVQSGLVVTDNTKESFQSIFSMTNEIAGKLQTMNSTVEQLSDRSQHVSAAVSGIADVSKESSASIQDIAASAEEQLASMEEISSSATTLAQMAEELRDLTKQFKIE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	662 (617)
Sequences:	7605 (6588)
Seq/√Len:	265.2

ECOLI - AER MCP3 MCP4 MCP1 MCP2
BACSU - MCPB MCPA TLPA TLPB MCPC TLPC YVAQ YOAH
HALSA - COST HTR4 HTR2 Q9HRA1 Q9HR88 Q9HRN6 Q9HP10 Q9HQX8 Q9HPA2 HTR7 Q9HS86 Q9HPQ5 HTR9 HMAT HTR1 Q9HQT5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
333_S	338_G	6.182	1.00
328_T	352_R	4.106	1.00
16_K	335_D	3.864	1.00
319_T	324_D	3.460	1.00
14_S	304_R	3.327	1.00
34_F	38_R	3.305	1.00
335_D	338_G	3.196	1.00
317_S	347_M	2.671	1.00
472_G	475_K	2.569	1.00
318_K	339_E	2.493	1.00
113_Y	181_A	2.488	1.00
499_A	520_R	2.487	1.00
328_T	349_Q	2.476	1.00
466_V	547_S	2.438	1.00
303_V	307_T	2.432	1.00
328_T	345_N	2.394	1.00
201_E	272_E	2.366	1.00
205_F	265_A	2.359	1.00
482_R	486_G	2.312	1.00
256_T	263_K	2.303	1.00
12_S	15_K	2.300	1.00
552_K	556_Q	2.257	1.00
456_I	561_G	2.241	1.00
249_D	270_M	2.237	1.00
282_T	286_I	2.235	1.00
473_K	543_E	2.217	1.00
566_D	570_E	2.208	1.00
286_I	290_A	2.204	1.00
198_V	202_G	2.141	1.00
142_Q	146_K	2.140	1.00
36_S	284_G	2.119	1.00
526_S	530_A	2.113	1.00
478_T	541_V	2.080	1.00
469_G	543_E	2.075	1.00
499_A	517_E	2.065	1.00
521_K	524_V	2.040	1.00
313_L	317_S	2.040	1.00
473_K	539_E	2.019	1.00
304_R	308_K	2.017	1.00
159_A	162_D	2.014	1.00
143_D	146_K	1.997	1.00
428_I	586_L	1.992	1.00
476_D	479_S	1.989	1.00
442_G	572_F	1.983	1.00
134_D	137_Q	1.978	1.00
168_T	183_D	1.969	1.00
642_A	645_L	1.969	1.00
345_N	348_G	1.964	1.00
623_D	626_A	1.953	1.00
563_V	567_N	1.916	1.00
320_I	347_M	1.913	1.00
420_Q	423_Q	1.897	1.00
441_T	444_K	1.896	1.00
314_V	339_E	1.894	1.00
444_K	448_Q	1.888	1.00
480_I	536_L	1.886	1.00
556_Q	559_Q	1.882	1.00
479_S	482_R	1.878	1.00
483_V	529_S	1.877	1.00
319_T	327_E	1.870	1.00
157_Y	168_T	1.866	1.00
471_E	548_L	1.861	1.00
339_E	342_E	1.858	1.00
317_S	344_F	1.850	1.00
474_S	544_I	1.847	1.00
567_N	570_E	1.838	1.00
517_E	520_R	1.831	1.00
100_S	104_S	1.821	1.00
448_Q	451_G	1.812	1.00
367_A	371_Q	1.808	1.00
314_V	343_S	1.798	1.00
299_I	303_V	1.798	1.00
591_S	594_E	1.759	1.00
239_G	254_Y	1.751	1.00
406_S	409_H	1.750	1.00
317_S	340_L	1.738	1.00
485_N	530_A	1.725	1.00
231_A	235_A	1.720	1.00
619_A	623_D	1.707	1.00
608_S	612_D	1.683	1.00
472_G	476_D	1.670	1.00
616_E	619_A	1.667	1.00
203_Y	217_K	1.667	1.00
33_E	288_L	1.666	1.00
442_G	575_I	1.659	1.00
595_Q	598_D	1.655	1.00
438_I	574_S	1.645	1.00
349_Q	353_S	1.643	1.00
612_D	615_K	1.635	1.00
560_S	563_V	1.633	1.00
228_D	231_A	1.629	1.00
534_E	538_Q	1.627	1.00
40_A	280_V	1.621	1.00
331_I	345_N	1.620	1.00
450_V	569_K	1.618	1.00
374_A	378_Q	1.609	1.00
227_G	231_A	1.605	1.00
116_A	120_T	1.601	1.00
379_T	383_T	1.600	1.00
559_Q	563_V	1.588	1.00
467_V	548_L	1.583	1.00
430_K	434_Q	1.581	1.00
466_V	546_T	1.581	1.00
453_M	456_I	1.581	1.00
28_P	291_S	1.580	1.00
402_E	405_E	1.580	1.00
318_K	322_R	1.578	1.00
370_E	374_A	1.571	1.00
601_Q	605_A	1.559	1.00
318_K	346_E	1.553	1.00
437_E	441_T	1.552	1.00
619_A	622_Q	1.547	1.00
528_D	532_E	1.545	1.00
449_T	568_T	1.544	1.00
164_S	187_D	1.538	1.00
147_A	150_E	1.532	1.00
203_Y	216_H	1.528	1.00
570_E	574_S	1.527	1.00
630_E	633_A	1.522	1.00
64_T	68_G	1.521	1.00
352_R	356_S	1.512	1.00
545_D	549_H	1.512	1.00
318_K	343_S	1.508	1.00
556_Q	560_S	1.507	1.00
199_G	202_G	1.506	1.00
473_K	476_D	1.503	1.00
191_E	194_K	1.496	1.00
153_V	169_I	1.496	1.00
574_S	577_S	1.489	1.00
636_E	640_S	1.488	1.00
188_K	191_E	1.477	1.00
33_E	37_Y	1.474	1.00
469_G	472_G	1.473	1.00
119_G	136_R	1.471	1.00
403_K	609_G	1.466	1.00
212_T	224_K	1.462	1.00
320_I	348_G	1.458	1.00
612_D	616_E	1.456	1.00
609_G	612_D	1.453	1.00
581_E	584_G	1.453	1.00
467_V	547_S	1.452	1.00
248_E	269_Y	1.452	1.00
204_A	266_G	1.441	1.00
155_D	210_N	1.433	1.00
367_A	370_E	1.433	1.00
602_H	605_A	1.432	1.00
91_N	94_E	1.432	1.00
313_L	340_L	1.425	1.00
451_G	455_S	1.420	1.00
412_N	416_E	1.418	1.00
414_M	600_S	1.416	1.00
426_S	430_K	1.413	1.00
459_S	553_E	1.412	1.00
279_S	283_T	1.409	1.00
433_I	437_E	1.407	1.00
434_Q	437_E	1.403	1.00
340_L	344_F	1.396	1.00
156_P	165_M	1.396	1.00
629_E	633_A	1.393	1.00
252_M	265_A	1.389	1.00
191_E	195_Q	1.388	1.00
328_T	348_G	1.386	1.00
310_L	340_L	1.383	1.00
453_M	561_G	1.376	1.00
290_A	294_A	1.373	1.00
377_G	381_K	1.367	1.00
281_L	285_M	1.366	1.00
440_G	444_K	1.364	1.00
52_A	56_V	1.356	1.00
353_S	357_A	1.351	1.00
528_D	531_K	1.351	1.00
187_D	191_E	1.346	1.00
317_S	343_S	1.340	1.00
92_Q	96_K	1.339	1.00
149_G	174_K	1.326	1.00
591_S	595_Q	1.326	1.00
114_G	173_L	1.322	1.00
594_E	598_D	1.321	1.00
242_Q	270_M	1.321	1.00
199_G	272_E	1.319	1.00
584_G	588_T	1.318	1.00
531_K	535_K	1.317	1.00
462_Q	465_A	1.315	1.00
399_E	402_E	1.309	1.00
580_N	584_G	1.308	1.00
152_V	170_A	1.307	1.00
283_T	286_I	1.307	1.00
371_Q	374_A	1.306	1.00
427_D	430_K	1.303	1.00
470_L	547_S	1.302	1.00
470_L	540_I	1.298	1.00
144_A	170_A	1.298	1.00
577_S	581_E	1.296	1.00
458_Q	462_Q	1.292	1.00
22_I	296_G	1.284	1.00
460_V	558_V	1.279	1.00
496_L	504_R	1.276	1.00
633_A	636_E	1.270	1.00
324_D	327_E	1.269	1.00
626_A	629_E	1.268	1.00
486_G	489_D	1.267	1.00
448_Q	567_N	1.266	1.00
293_V	297_I	1.265	1.00
305_S	308_K	1.262	1.00
250_K	269_Y	1.254	1.00
430_K	433_I	1.245	1.00
524_V	528_D	1.244	1.00
588_T	591_S	1.242	1.00
423_Q	427_D	1.238	1.00
447_Q	451_G	1.238	1.00
141_Y	145_M	1.238	1.00
270_M	274_K	1.237	1.00
454_N	458_Q	1.235	1.00
14_S	18_I	1.235	1.00
13_I	337_L	1.233	1.00
47_E	51_N	1.223	1.00
109_V	182_M	1.223	1.00
572_F	575_I	1.219	1.00
331_I	341_G	1.218	1.00
313_L	341_G	1.216	1.00
11_P	19_V	1.214	1.00
37_Y	281_L	1.214	1.00
157_Y	183_D	1.211	1.00
492_N	520_R	1.211	1.00
203_Y	267_T	1.199	1.00
29_I	32_L	1.199	1.00
331_I	335_D	1.196	1.00
549_H	552_K	1.195	1.00
626_A	630_E	1.191	1.00
465_A	469_G	1.191	1.00
72_K	75_T	1.189	1.00
11_P	15_K	1.184	1.00
402_E	406_S	1.180	1.00
35_S	39_S	1.177	1.00
142_Q	145_M	1.175	1.00
495_A	520_R	1.175	1.00
409_H	413_L	1.174	1.00
467_V	551_F	1.173	1.00
452_Q	560_S	1.172	1.00
232_K	237_D	1.171	1.00
313_L	344_F	1.170	1.00
320_I	325_L	1.163	1.00
139_P	143_D	1.161	1.00
444_K	447_Q	1.160	1.00
230_V	233_M	1.160	1.00
437_E	440_G	1.160	1.00
282_T	285_M	1.153	1.00
380_S	383_T	1.149	1.00
535_K	539_E	1.146	1.00
96_K	100_S	1.145	1.00
25_L	28_P	1.144	1.00
461_Q	555_N	1.143	1.00
320_I	344_F	1.143	1.00
285_M	289_I	1.141	1.00
75_T	151_I	1.138	1.00
458_Q	461_Q	1.137	1.00
244_T	249_D	1.137	1.00
553_E	556_Q	1.137	1.00
316_S	329_I	1.134	1.00
454_N	566_D	1.133	1.00
38_R	42_G	1.131	1.00
451_G	454_N	1.131	1.00
71_A	75_T	1.130	1.00
21_F	299_I	1.127	1.00
461_Q	465_A	1.127	1.00
18_I	22_I	1.127	1.00
319_T	347_M	1.123	1.00
362_V	369_S	1.120	1.00
66_D	70_K	1.118	1.00
232_K	236_N	1.118	1.00
443_E	573_Q	1.117	1.00
549_H	553_E	1.116	1.00
289_I	293_V	1.115	1.00
359_Q	363_N	1.102	1.00
243_Y	250_K	1.101	1.00
520_R	524_V	1.100	1.00
480_I	537_I	1.099	1.00
622_Q	626_A	1.099	1.00
620_S	623_D	1.098	1.00
297_I	301_F	1.098	1.00
144_A	179_V	1.097	1.00
476_D	532_E	1.096	1.00
508_S	519_V	1.095	1.00
250_K	267_T	1.093	1.00
74_V	171_Q	1.093	1.00
531_K	534_E	1.092	1.00
485_N	534_E	1.091	1.00
419_Q	423_Q	1.090	1.00
605_A	609_G	1.090	1.00
200_K	272_E	1.090	1.00
527_A	531_K	1.089	1.00
538_Q	542_A	1.088	1.00
468_K	472_G	1.087	1.00
584_G	587_Q	1.085	1.00
400_Q	404_V	1.080	1.00
243_Y	252_M	1.079	1.00
314_V	318_K	1.078	1.00
638_I	645_L	1.078	1.00
480_I	529_S	1.073	1.00
414_M	596_L	1.071	1.00
525_Q	528_D	1.070	1.00
325_L	351_L	1.069	1.00
41_S	45_D	1.069	1.00
325_L	355_I	1.068	1.00
40_A	44_L	1.065	1.00
71_A	153_V	1.064	1.00
121_Y	124_A	1.062	1.00
356_S	360_D	1.062	1.00
465_A	468_K	1.060	1.00
320_I	351_L	1.059	1.00
525_Q	532_E	1.056	1.00
489_D	500_I	1.048	1.00
45_D	49_M	1.046	1.00
637_E	640_S	1.044	1.00
17_L	21_F	1.042	1.00
154_T	157_Y	1.040	1.00
410_Q	413_L	1.039	1.00
587_Q	591_S	1.038	1.00
439_A	442_G	1.036	1.00
115_G	135_P	1.036	1.00
329_I	345_N	1.035	1.00
70_K	73_A	1.034	1.00
344_F	348_G	1.034	1.00
30_L	34_F	1.034	1.00
624_I	627_S	1.033	1.00
316_S	344_F	1.032	1.00
464_E	551_F	1.031	1.00
170_A	179_V	1.028	1.00
38_R	41_S	1.026	1.00
631_Q	635_M	1.025	1.00
466_V	550_M	1.019	1.00
638_I	642_A	1.017	1.00
542_A	546_T	1.016	1.00
56_V	60_N	1.012	1.00
376_A	383_T	1.009	1.00
348_G	352_R	1.007	1.00
312_R	330_E	1.006	1.00
295_G	299_I	1.006	1.00
369_S	376_A	1.005	1.00
25_L	295_G	1.003	1.00
60_N	257_N	1.003	1.00
296_G	300_L	1.003	1.00
517_E	521_K	1.003	1.00
245_L	250_K	1.002	1.00
322_R	346_E	1.000	1.00
464_E	555_N	0.999	1.00
93_E	97_A	0.998	1.00
635_M	645_L	0.997	1.00
611_A	615_K	0.996	1.00
439_A	576_F	0.996	1.00
470_L	544_I	0.993	1.00
598_D	602_H	0.992	1.00
29_I	288_L	0.992	1.00
26_I	30_L	0.990	1.00
314_V	340_L	0.988	1.00
94_E	97_A	0.987	1.00
323_G	347_M	0.986	1.00
228_D	232_K	0.986	1.00
341_G	345_N	0.982	1.00
323_G	340_L	0.981	1.00
416_E	420_Q	0.980	1.00
315_Q	318_K	0.979	1.00
151_I	171_Q	0.978	1.00
495_A	519_V	0.978	1.00
449_T	565_T	0.975	1.00
33_E	284_G	0.972	1.00
475_K	545_D	0.972	1.00
74_V	182_M	0.970	1.00
340_L	347_M	0.969	1.00
425_S	428_I	0.964	1.00
334_K	338_G	0.962	1.00
278_K	281_L	0.961	1.00
278_K	282_T	0.961	1.00
547_S	551_F	0.955	1.00
570_E	573_Q	0.955	1.00
459_S	462_Q	0.955	1.00
376_A	380_S	0.955	1.00
360_D	363_N	0.954	1.00
493_L	500_I	0.953	1.00
563_V	566_D	0.953	1.00
155_D	208_T	0.950	1.00
316_S	327_E	0.950	1.00
20_S	302_I	0.949	1.00
51_N	54_N	0.948	1.00
231_A	234_Y	0.945	1.00
537_I	541_V	0.941	1.00
156_P	208_T	0.938	1.00
309_P	333_S	0.938	1.00
363_N	367_A	0.937	1.00
137_Q	142_Q	0.937	1.00
36_S	40_A	0.936	1.00
448_Q	564_V	0.934	1.00
354_L	358_I	0.934	1.00
73_A	76_F	0.933	1.00
233_M	265_A	0.932	1.00
605_A	608_S	0.925	1.00
113_Y	183_D	0.923	1.00
344_F	347_M	0.922	1.00
138_R	160_A	0.920	1.00
573_Q	577_S	0.919	1.00
523_A	526_S	0.917	1.00
311_K	314_V	0.917	1.00
411_L	607_V	0.915	1.00
374_A	377_G	0.915	1.00
455_S	557_E	0.914	1.00
455_S	458_Q	0.913	1.00
64_T	259_L	0.913	1.00
347_M	351_L	0.910	1.00
300_L	304_R	0.910	1.00
615_K	619_A	0.909	1.00
158_V	163_G	0.908	1.00
68_G	71_A	0.903	1.00
460_V	551_F	0.902	1.00
624_I	631_Q	0.901	1.00
421_V	579_T	0.901	1.00
436_T	440_G	0.900	1.00
346_E	349_Q	0.897	1.00
634_S	638_I	0.896	1.00
205_F	216_H	0.896	1.00
50_G	54_N	0.896	1.00
312_R	315_Q	0.892	1.00
439_A	443_E	0.891	1.00
251_K	270_M	0.891	1.00
468_K	552_K	0.891	1.00
317_S	320_I	0.891	1.00
115_G	140_W	0.887	1.00
140_W	157_Y	0.887	1.00
541_V	548_L	0.887	1.00
248_E	271_D	0.886	1.00
480_I	530_A	0.883	1.00
312_R	316_S	0.882	1.00
456_I	558_V	0.882	1.00
174_K	177_S	0.881	1.00
303_V	306_I	0.880	1.00
591_S	598_D	0.878	1.00
290_A	297_I	0.876	1.00
421_V	593_V	0.871	1.00
412_N	415_N	0.871	1.00
309_P	337_L	0.871	1.00
469_G	546_T	0.869	1.00
400_Q	614_S	0.867	1.00
164_S	185_T	0.866	1.00
331_I	342_E	0.865	1.00
532_E	535_K	0.865	1.00
138_R	159_A	0.865	1.00
464_E	552_K	0.863	1.00
613_V	617_S	0.863	1.00
639_S	643_T	0.863	1.00
480_I	526_S	0.862	1.00
56_V	266_G	0.861	1.00
422_S	425_S	0.861	1.00
413_L	416_E	0.856	1.00
125_P	128_K	0.855	1.00
101_Q	104_S	0.854	1.00
275_D	279_S	0.854	1.00
429_T	433_I	0.854	1.00
120_T	134_D	0.853	1.00
463_A	554_V	0.853	1.00
423_Q	426_S	0.850	1.00
136_R	141_Y	0.850	1.00
53_K	57_D	0.850	1.00
378_Q	381_K	0.850	1.00
453_M	565_T	0.848	1.00
16_K	305_S	0.845	1.00
474_S	480_I	0.845	1.00
412_N	604_S	0.845	1.00
158_V	165_M	0.844	0.99
633_A	637_E	0.843	0.99
376_A	379_T	0.843	0.99
358_I	365_V	0.841	0.99
413_L	417_G	0.840	0.99
356_S	359_Q	0.840	0.99
631_Q	638_I	0.836	0.99
588_T	592_T	0.836	0.99
641_S	644_T	0.833	0.99
123_Q	127_E	0.833	0.99
561_G	568_T	0.833	0.99
200_K	275_D	0.832	0.99
457_N	562_L	0.831	0.99
539_E	543_E	0.830	0.99
123_Q	126_K	0.829	0.99
134_D	138_R	0.829	0.99
232_K	235_A	0.823	0.99
369_S	372_L	0.823	0.99
365_V	368_S	0.823	0.99
140_W	179_V	0.821	0.99
37_Y	277_S	0.820	0.99
418_L	596_L	0.819	0.99
45_D	274_K	0.819	0.99
13_I	336_E	0.816	0.99
426_S	594_E	0.816	0.99
205_F	267_T	0.815	0.99
279_S	282_T	0.812	0.99
432_S	579_T	0.812	0.99
405_E	409_H	0.812	0.99
433_I	587_Q	0.811	0.99
11_P	334_K	0.809	0.99
408_S	413_L	0.809	0.99
319_T	322_R	0.809	0.99
544_I	547_S	0.808	0.99
15_K	19_V	0.807	0.99
464_E	547_S	0.806	0.99
338_G	341_G	0.806	0.99
459_S	557_E	0.803	0.99
575_I	578_M	0.803	0.99
61_T	64_T	0.802	0.99
331_I	338_G	0.802	0.99
133_Y	138_R	0.800	0.99
133_Y	140_W	0.800	0.99
617_S	638_I	0.799	0.99
59_F	62_T	0.799	0.99
307_T	311_K	0.798	0.99
476_D	539_E	0.798	0.99
413_L	599_R	0.798	0.99
69_E	72_K	0.797	0.99
257_N	260_T	0.795	0.99
37_Y	41_S	0.790	0.99
12_S	339_E	0.790	0.99
623_D	627_S	0.788	0.99
316_S	320_I	0.787	0.99
131_E	135_P	0.786	0.99
493_L	521_K	0.785	0.99
449_T	456_I	0.782	0.99
366_A	370_E	0.782	0.99
583_A	587_Q	0.781	0.99
526_S	536_L	0.777	0.99
452_Q	455_S	0.777	0.99
46_Q	50_G	0.777	0.99
141_Y	179_V	0.776	0.99
22_I	26_I	0.776	0.99
372_L	376_A	0.775	0.99
74_V	78_S	0.773	0.99
280_V	284_G	0.773	0.99
544_I	548_L	0.773	0.99
170_A	181_A	0.773	0.99
554_V	561_G	0.772	0.99
406_S	410_Q	0.772	0.99
133_Y	136_R	0.771	0.99
110_A	159_A	0.770	0.99
404_V	610_I	0.770	0.99
103_V	112_I	0.769	0.99
432_S	582_I	0.768	0.99
607_V	610_I	0.768	0.99
424_T	588_T	0.767	0.99
159_A	166_V	0.765	0.99
154_T	170_A	0.765	0.99
607_V	611_A	0.765	0.99
149_G	172_E	0.763	0.99
409_H	412_N	0.763	0.99
337_L	341_G	0.760	0.99
590_N	594_E	0.760	0.99
360_D	364_N	0.760	0.99
417_G	592_T	0.759	0.99
542_A	545_D	0.758	0.99
329_I	341_G	0.757	0.99
357_A	360_D	0.756	0.99
74_V	169_I	0.756	0.99
445_F	567_N	0.755	0.99
311_K	315_Q	0.754	0.99
143_D	170_A	0.753	0.99
291_S	295_G	0.753	0.99
410_Q	414_M	0.751	0.99
49_M	53_K	0.750	0.99
348_G	351_L	0.750	0.99
353_S	356_S	0.747	0.99
463_A	551_F	0.746	0.99
407_S	606_A	0.743	0.99
631_Q	645_L	0.743	0.99
97_A	101_Q	0.742	0.99
519_V	525_Q	0.742	0.99
446_V	449_T	0.742	0.99
576_F	580_N	0.741	0.99
557_E	560_S	0.741	0.99
416_E	419_Q	0.740	0.99
151_I	169_I	0.739	0.99
97_A	100_S	0.738	0.99
564_V	567_N	0.738	0.99
135_P	140_W	0.737	0.99
638_I	641_S	0.737	0.99
486_G	525_Q	0.735	0.99
68_G	72_K	0.735	0.99
378_Q	382_A	0.734	0.99
178_G	181_A	0.734	0.99
166_V	183_D	0.734	0.99
32_L	36_S	0.733	0.99
143_D	147_A	0.732	0.99
11_P	16_K	0.731	0.99
135_P	138_R	0.730	0.99
495_A	524_V	0.730	0.99
313_L	329_I	0.729	0.99
460_V	554_V	0.728	0.99
565_T	568_T	0.727	0.99
474_S	478_T	0.726	0.98
345_N	349_Q	0.726	0.98
440_G	443_E	0.726	0.98
25_L	299_I	0.725	0.98
14_S	307_T	0.725	0.98
140_W	168_T	0.724	0.98
492_N	499_A	0.723	0.98
135_P	141_Y	0.722	0.98
208_T	212_T	0.721	0.98
372_L	383_T	0.721	0.98
428_I	435_S	0.721	0.98
414_M	599_R	0.719	0.98
489_D	493_L	0.719	0.98
474_S	540_I	0.718	0.98
471_E	475_K	0.717	0.98
577_S	580_N	0.716	0.98
443_E	447_Q	0.715	0.98
93_E	96_K	0.715	0.98
481_L	485_N	0.715	0.98
35_S	287_V	0.715	0.98
304_R	311_K	0.714	0.98
169_I	184_I	0.714	0.98
457_N	461_Q	0.713	0.98
411_L	418_L	0.712	0.98
16_K	333_S	0.712	0.98
540_I	544_I	0.710	0.98
446_V	572_F	0.710	0.98
193_M	206_I	0.710	0.98
565_T	575_I	0.710	0.98
350_S	353_S	0.709	0.98
479_S	483_V	0.709	0.98
309_P	338_G	0.707	0.98
71_A	151_I	0.707	0.98
138_R	144_A	0.706	0.98
140_W	181_A	0.706	0.98
140_W	144_A	0.705	0.98
374_A	381_K	0.705	0.98
480_I	483_V	0.703	0.98
144_A	147_A	0.703	0.98
323_G	354_L	0.701	0.98
139_P	142_Q	0.700	0.98
414_M	603_V	0.699	0.98
481_L	533_I	0.699	0.98
317_S	351_L	0.699	0.98
209_K	261_G	0.698	0.98
625_A	628_A	0.697	0.98
367_A	374_A	0.696	0.98
140_W	183_D	0.696	0.98
442_G	446_V	0.696	0.98
178_G	183_D	0.694	0.98
13_I	310_L	0.694	0.98
75_T	171_Q	0.693	0.98
427_D	585_K	0.692	0.98
418_L	593_V	0.691	0.98
78_S	171_Q	0.690	0.98
581_E	585_K	0.690	0.98
368_S	379_T	0.689	0.98
198_V	266_G	0.689	0.98
143_D	152_V	0.689	0.98
321_S	346_E	0.687	0.98
111_R	116_A	0.687	0.98
60_N	255_T	0.687	0.98
271_D	274_K	0.684	0.98
242_Q	249_D	0.684	0.98
111_R	115_G	0.683	0.98
617_S	620_S	0.683	0.98
453_M	562_L	0.682	0.98
301_F	304_R	0.682	0.98
373_T	376_A	0.679	0.98
212_T	215_A	0.678	0.98
428_I	432_S	0.678	0.98
508_S	513_S	0.678	0.98
435_S	579_T	0.678	0.98
612_D	619_A	0.675	0.98
636_E	639_S	0.674	0.98
274_K	277_S	0.673	0.98
144_A	172_E	0.671	0.97
641_S	645_L	0.671	0.97
28_P	295_G	0.671	0.97
347_M	352_R	0.671	0.97
535_K	538_Q	0.670	0.97
67_L	169_I	0.670	0.97
159_A	183_D	0.668	0.97
141_Y	168_T	0.668	0.97
115_G	121_Y	0.668	0.97
481_L	534_E	0.667	0.97
469_G	473_K	0.667	0.97
236_N	256_T	0.667	0.97
635_M	638_I	0.666	0.97
441_T	571_S	0.666	0.97
190_L	215_A	0.665	0.97
541_V	545_D	0.664	0.97
400_Q	414_M	0.663	0.97
595_Q	599_R	0.662	0.97
198_V	272_E	0.660	0.97
59_F	204_A	0.660	0.97
135_P	139_P	0.659	0.97
438_I	441_T	0.659	0.97
201_E	269_Y	0.659	0.97
411_L	414_M	0.658	0.97
264_I	269_Y	0.658	0.97
60_N	64_T	0.658	0.97
89_K	92_Q	0.655	0.97
207_A	265_A	0.655	0.97
372_L	375_S	0.655	0.97
463_A	550_M	0.654	0.97
414_M	417_G	0.654	0.97
136_R	140_W	0.653	0.97
26_I	292_I	0.652	0.97
449_T	453_M	0.651	0.97
111_R	183_D	0.651	0.97
463_A	467_V	0.650	0.97
481_L	530_A	0.649	0.97
143_D	150_E	0.648	0.97
558_V	561_G	0.646	0.97
88_G	91_N	0.644	0.97
561_G	600_S	0.644	0.97
193_M	204_A	0.643	0.97
202_G	272_E	0.643	0.97
230_V	234_Y	0.641	0.97
206_I	264_I	0.640	0.97
111_R	125_P	0.640	0.97
168_T	181_A	0.639	0.97
114_G	178_G	0.637	0.97
626_A	633_A	0.637	0.97
115_G	138_R	0.636	0.97
422_S	597_S	0.635	0.97
375_S	379_T	0.634	0.96
342_E	345_N	0.632	0.96
321_S	343_S	0.630	0.96
347_M	350_S	0.629	0.96
198_V	201_E	0.629	0.96
115_G	141_Y	0.629	0.96
36_S	280_V	0.628	0.96
619_A	626_A	0.627	0.96
46_Q	276_A	0.625	0.96
326_T	352_R	0.625	0.96
399_E	403_K	0.624	0.96
34_F	37_Y	0.623	0.96
115_G	181_A	0.622	0.96
131_E	134_D	0.622	0.96
566_D	569_K	0.621	0.96
410_Q	417_G	0.619	0.96
400_Q	407_S	0.618	0.96
252_M	267_T	0.616	0.96
414_M	421_V	0.616	0.96
442_G	568_T	0.614	0.96
24_I	28_P	0.613	0.96
132_G	140_W	0.613	0.96
446_V	565_T	0.613	0.96
13_I	306_I	0.611	0.96
362_V	365_V	0.609	0.96
341_G	344_F	0.609	0.96
90_S	94_E	0.607	0.95
585_K	589_M	0.606	0.95
158_V	162_D	0.604	0.95
401_S	404_V	0.604	0.95
112_I	182_M	0.604	0.95
309_P	340_L	0.601	0.95
589_M	596_L	0.601	0.95
140_W	159_A	0.600	0.95
403_K	406_S	0.600	0.95
582_I	585_K	0.600	0.95
159_A	163_G	0.599	0.95
301_F	305_S	0.599	0.95
471_E	545_D	0.598	0.95
65_N	68_G	0.598	0.95
489_D	499_A	0.598	0.95
436_T	583_A	0.597	0.95
29_I	295_G	0.597	0.95
490_Q	525_Q	0.597	0.95
75_T	79_E	0.596	0.95
361_S	364_N	0.595	0.95
432_S	442_G	0.594	0.95
110_A	185_T	0.593	0.95
154_T	159_A	0.592	0.95
495_A	499_A	0.591	0.95
99_F	103_V	0.590	0.95
617_S	621_I	0.590	0.95
303_V	310_L	0.589	0.95
434_Q	574_S	0.588	0.95
358_I	361_S	0.588	0.95
457_N	559_Q	0.587	0.95
407_S	414_M	0.587	0.95
47_E	276_A	0.586	0.95
11_P	14_S	0.586	0.95
445_F	448_Q	0.585	0.95
471_E	474_S	0.585	0.95
415_N	600_S	0.585	0.95
485_N	531_K	0.585	0.95
112_I	180_V	0.585	0.95
474_S	561_G	0.583	0.94
470_L	480_I	0.583	0.94
407_S	603_V	0.582	0.94
308_K	311_K	0.581	0.94
546_T	549_H	0.581	0.94
124_A	128_K	0.581	0.94
434_Q	438_I	0.580	0.94
468_K	471_E	0.580	0.94
136_R	139_P	0.580	0.94
446_V	450_V	0.578	0.94
185_T	188_K	0.577	0.94
421_V	428_I	0.577	0.94
489_D	527_A	0.577	0.94
63_V	262_W	0.576	0.94
628_A	635_M	0.576	0.94
460_V	463_A	0.576	0.94
582_I	586_L	0.576	0.94
593_V	596_L	0.576	0.94
318_K	321_S	0.575	0.94
417_G	591_S	0.575	0.94
425_S	589_M	0.575	0.94
483_V	523_A	0.572	0.94
495_A	517_E	0.572	0.94
120_T	124_A	0.572	0.94
276_A	279_S	0.571	0.94
539_E	542_A	0.571	0.94
20_S	295_G	0.571	0.94
368_S	371_Q	0.571	0.94
120_T	127_E	0.571	0.94
325_L	347_M	0.570	0.94
70_K	182_M	0.570	0.94
216_H	219_H	0.569	0.94
36_S	295_G	0.568	0.94
154_T	168_T	0.568	0.94
632_L	636_E	0.568	0.94
618_S	621_I	0.567	0.94
334_K	342_E	0.566	0.94
408_S	604_S	0.565	0.93
415_N	418_L	0.565	0.93
470_L	631_Q	0.564	0.93
467_V	471_E	0.564	0.93
222_G	226_S	0.564	0.93
480_I	486_G	0.563	0.93
327_E	347_M	0.562	0.93
596_L	599_R	0.561	0.93
92_Q	95_I	0.560	0.93
17_L	303_V	0.560	0.93
412_N	417_G	0.559	0.93
547_S	554_V	0.559	0.93
569_K	573_Q	0.558	0.93
335_D	341_G	0.558	0.93
547_S	550_M	0.556	0.93
415_N	604_S	0.556	0.93
441_T	567_N	0.556	0.93
364_N	367_A	0.555	0.93
59_F	196_I	0.554	0.93
477_I	530_A	0.554	0.93
346_E	350_S	0.553	0.93
439_A	575_I	0.552	0.93
616_E	620_S	0.552	0.93
446_V	568_T	0.552	0.93
610_I	617_S	0.552	0.93
70_K	109_V	0.551	0.93
505_A	519_V	0.551	0.93
47_E	50_G	0.551	0.93
403_K	606_A	0.551	0.93
537_I	547_S	0.550	0.93
482_R	485_N	0.550	0.93
56_V	255_T	0.549	0.92
111_R	124_A	0.549	0.92
193_M	215_A	0.549	0.92
438_I	578_M	0.549	0.92
471_E	544_I	0.548	0.92
121_Y	135_P	0.547	0.92
485_N	489_D	0.547	0.92
173_L	177_S	0.547	0.92
477_I	537_I	0.547	0.92
137_Q	140_W	0.545	0.92
601_Q	604_S	0.543	0.92
55_S	58_T	0.543	0.92
308_K	312_R	0.543	0.92
425_S	586_L	0.542	0.92
632_L	635_M	0.541	0.92
39_S	42_G	0.541	0.92
517_E	525_Q	0.540	0.92
134_D	140_W	0.539	0.92
627_S	630_E	0.539	0.92
476_D	536_L	0.539	0.92
565_T	569_K	0.538	0.92
640_S	644_T	0.538	0.92
257_N	261_G	0.538	0.92
634_S	637_E	0.537	0.92
537_I	540_I	0.537	0.92
257_N	264_I	0.536	0.92
124_A	127_E	0.536	0.92
455_S	459_S	0.535	0.91
572_F	582_I	0.535	0.91
66_D	69_E	0.535	0.91
585_K	588_T	0.534	0.91
119_G	122_V	0.533	0.91
287_V	291_S	0.532	0.91
98_K	101_Q	0.532	0.91
22_I	28_P	0.529	0.91
307_T	310_L	0.528	0.91
439_A	456_I	0.526	0.91
319_T	350_S	0.526	0.91
554_V	558_V	0.523	0.91
213_Y	216_H	0.523	0.91
609_G	613_V	0.521	0.90
435_S	582_I	0.520	0.90
417_G	589_M	0.520	0.90
492_N	495_A	0.520	0.90
18_I	21_F	0.520	0.90
452_Q	564_V	0.519	0.90
133_Y	137_Q	0.519	0.90
254_Y	265_A	0.518	0.90
13_I	307_T	0.517	0.90
417_G	599_R	0.516	0.90
435_S	442_G	0.515	0.90
447_Q	569_K	0.515	0.90
631_Q	634_S	0.514	0.90
519_V	529_S	0.514	0.90
307_T	337_L	0.513	0.90
490_Q	518_E	0.512	0.90
435_S	446_V	0.512	0.90
621_I	628_A	0.512	0.90
442_G	456_I	0.511	0.90
246_N	249_D	0.511	0.90
454_N	457_N	0.510	0.89
404_V	411_L	0.510	0.89
314_V	337_L	0.510	0.89
317_S	348_G	0.509	0.89
18_I	23_A	0.507	0.89
271_D	278_K	0.506	0.89
345_N	352_R	0.505	0.89
112_I	115_G	0.505	0.89
473_K	536_L	0.504	0.89
307_T	314_V	0.504	0.89
115_G	133_Y	0.503	0.89
141_Y	166_V	0.503	0.89
91_N	95_I	0.503	0.89
52_A	253_T	0.503	0.89
132_G	136_R	0.500	0.89

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.4577	100	0.511	Contact Map
2ch7A	2	0.4668	100	0.587	Contact Map
1qu7A	2	0.3399	100	0.618	Contact Map
3g67A	2	0.3157	100	0.672	Contact Map
4i3mA	2	0.2221	99.9	0.794	Contact Map
3lifA	1	0.355	99.9	0.809	Contact Map
3c8cA	2	0.3505	99.9	0.821	Contact Map
3li9A	2	0.3369	99.9	0.822	Contact Map
3libA	3	0.3505	99.9	0.823	Contact Map
3lidA	2	0.3701	99.9	0.823	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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