TLPC - BACSU - GREMLIN Contacts

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TLPC - Methyl-accepting chemotaxis protein TlpC

UniProt:	P39209	Sequences: MLIKRFKMKLGTKILCLVFVVILLFSASVGTVMLKEITESMKQMATEKAKGDLALSSTYIDDVMSGDWQVKNNKLYKGQTQINGNEDIVDLLGEKTGDTITIFQGDTRVATNVMKNGERAVGTQASSEVIAAVLKKGKRFYGQADVAGSSYQTAYMPLKDQNGNIIGMLYTGANQSILASLTQSLFTQFAIVLVIVIMVSVILVLVFTRKINKRLNALKSAFESAGNGDMTIEVSDKTGDELSELSVYYNKMRMKLNDTIQTVQQSALQLASASQQLSAGAEETNQASEKITEAVQQIANGAQDQITRIENSESSLKQASADIRDISANTAAIADKGQLAQSKADIGQKEIANVQAQMDAIHQSIQKSGEIIHQLDGRSKQIEQILSVITQIADQTNLLALNAAIEAARAGEQGKGFAVVADEVRKLAEESQQSAGQISKLIIEIQKDMNRSARSVEHVKTEAAEGVTMIQRTRDAFKEIAAATGEISAEISDLSASVTNISASAHQINDSFAANTADIKESTKNTRQAAALTEEQFAAMEEITAASETLSQLAEELTGIISQFKMINQAENG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	573 (523)
Sequences:	21214 (18499)
Seq/√Len:	808.9

ECOLI - MCP4 MCP3 MCP2 MCP1 AER
BACSU - TLPC TLPA MCPB MCPA TLPB MCPC YOAH YVAQ HEMAT
HALSA - HTR4 COST HTR2 Q9HRA1 Q9HS86 Q9HRN6 Q9HPA2 HTR7 Q9HQX8 Q9HP10 Q9HR88 HTR9 Q9HPQ5 HMAT HTR1 Q9HQT5 Q9HPW6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
238_T	243_S	4.932	1.00
224_S	229_D	3.900	1.00
9_K	12_T	3.390	1.00
233_E	257_N	3.285	1.00
13_K	240_D	2.959	1.00
250_N	253_R	2.819	1.00
224_S	232_I	2.590	1.00
374_Q	448_D	2.546	1.00
377_G	380_K	2.482	1.00
223_E	244_E	2.353	1.00
187_T	191_I	2.321	1.00
218_L	246_S	2.288	1.00
240_D	243_S	2.244	1.00
209_R	213_K	2.243	1.00
83_N	87_D	2.242	1.00
349_K	353_N	2.240	1.00
378_R	448_D	2.222	1.00
361_I	466_G	2.197	1.00
222_F	252_M	2.185	1.00
381_Q	384_Q	2.102	1.00
378_R	444_E	2.099	1.00
132_A	136_K	2.084	1.00
223_E	251_K	2.067	1.00
131_A	135_K	2.067	1.00
225_A	252_M	2.059	1.00
219_K	248_Y	2.054	1.00
342_S	346_I	2.045	1.00
31_T	35_K	2.044	1.00
219_K	244_E	2.031	1.00
208_T	212_N	2.020	1.00
372_I	452_S	2.008	1.00
222_F	249_Y	2.004	1.00
387_S	391_Q	2.001	1.00
225_A	253_R	2.001	1.00
431_S	435_A	1.987	1.00
325_D	328_A	1.985	1.00
464_A	468_T	1.936	1.00
383_E	446_Q	1.930	1.00
465_E	468_T	1.929	1.00
346_I	349_K	1.914	1.00
233_E	254_M	1.911	1.00
457_E	461_T	1.889	1.00
450_N	454_R	1.886	1.00
233_E	250_N	1.882	1.00
471_Q	475_D	1.882	1.00
191_I	195_I	1.879	1.00
461_T	465_E	1.869	1.00
468_T	472_R	1.862	1.00
426_K	429_E	1.859	1.00
184_S	188_Q	1.857	1.00
374_Q	377_G	1.828	1.00
244_E	247_V	1.823	1.00
163_G	167_G	1.819	1.00
222_F	248_Y	1.809	1.00
376_D	453_A	1.789	1.00
373_H	457_E	1.787	1.00
233_E	253_R	1.782	1.00
371_I	452_S	1.777	1.00
218_L	245_L	1.765	1.00
335_D	339_L	1.763	1.00
364_S	458_H	1.761	1.00
371_I	451_R	1.756	1.00
257_N	261_Q	1.738	1.00
129_V	132_A	1.735	1.00
258_D	262_T	1.732	1.00
528_Q	531_A	1.729	1.00
128_E	132_A	1.726	1.00
439_S	443_I	1.713	1.00
333_I	491_I	1.710	1.00
94_E	98_D	1.699	1.00
373_H	377_G	1.698	1.00
454_R	458_H	1.693	1.00
461_T	464_A	1.687	1.00
190_A	194_V	1.682	1.00
223_E	248_Y	1.680	1.00
384_Q	387_S	1.657	1.00
339_L	342_S	1.654	1.00
250_N	254_M	1.654	1.00
353_N	356_A	1.653	1.00
422_D	425_R	1.653	1.00
282_E	286_Q	1.641	1.00
118_E	122_G	1.633	1.00
272_S	276_Q	1.626	1.00
335_D	338_Q	1.614	1.00
13_K	210_K	1.614	1.00
355_Q	474_R	1.591	1.00
379_S	449_M	1.591	1.00
433_Q	437_Q	1.587	1.00
11_G	15_L	1.577	1.00
87_D	90_D	1.576	1.00
352_A	356_A	1.572	1.00
507_Q	510_D	1.560	1.00
472_R	475_D	1.560	1.00
222_F	245_L	1.555	1.00
11_G	209_R	1.551	1.00
332_A	335_D	1.548	1.00
223_E	227_N	1.542	1.00
28_S	32_V	1.538	1.00
218_L	249_Y	1.529	1.00
338_Q	342_S	1.527	1.00
186_F	190_A	1.526	1.00
375_L	452_S	1.524	1.00
42_K	46_T	1.516	1.00
390_T	439_S	1.515	1.00
183_Q	187_T	1.514	1.00
204_V	208_T	1.513	1.00
254_M	258_D	1.512	1.00
404_A	422_D	1.506	1.00
524_K	528_Q	1.505	1.00
236_D	250_N	1.500	1.00
372_I	456_V	1.498	1.00
345_D	349_K	1.495	1.00
381_Q	437_Q	1.491	1.00
458_H	461_T	1.490	1.00
513_A	517_A	1.488	1.00
343_K	479_E	1.485	1.00
229_D	232_I	1.479	1.00
308_R	514_A	1.479	1.00
78_G	81_Q	1.474	1.00
377_G	381_Q	1.471	1.00
521_E	524_K	1.458	1.00
87_D	91_L	1.453	1.00
119_R	123_T	1.450	1.00
29_V	33_M	1.446	1.00
132_A	135_K	1.446	1.00
279_A	283_E	1.445	1.00
500_N	503_A	1.428	1.00
486_E	489_A	1.427	1.00
264_Q	268_L	1.420	1.00
429_E	433_Q	1.414	1.00
493_D	496_A	1.413	1.00
311_N	314_S	1.410	1.00
214_R	241_E	1.406	1.00
86_E	90_D	1.398	1.00
524_K	527_R	1.395	1.00
276_Q	279_A	1.389	1.00
182_T	186_F	1.387	1.00
253_R	257_N	1.372	1.00
331_A	335_D	1.369	1.00
121_V	124_Q	1.368	1.00
324_R	328_A	1.367	1.00
514_A	517_A	1.367	1.00
317_K	321_A	1.356	1.00
90_D	94_E	1.351	1.00
129_V	133_V	1.346	1.00
120_A	124_Q	1.336	1.00
534_E	538_A	1.333	1.00
307_T	311_N	1.332	1.00
32_V	36_E	1.331	1.00
390_T	435_A	1.329	1.00
366_Q	370_E	1.320	1.00
275_Q	279_A	1.317	1.00
475_D	479_E	1.317	1.00
217_A	235_S	1.310	1.00
436_G	440_K	1.305	1.00
284_T	288_S	1.305	1.00
375_L	445_I	1.305	1.00
378_R	381_Q	1.304	1.00
404_A	425_R	1.304	1.00
56_S	60_I	1.301	1.00
479_E	482_A	1.300	1.00
344_A	481_A	1.299	1.00
265_Q	268_L	1.299	1.00
140_F	144_A	1.294	1.00
380_K	450_N	1.288	1.00
485_G	489_A	1.285	1.00
218_L	222_F	1.284	1.00
433_Q	436_G	1.284	1.00
527_R	531_A	1.279	1.00
328_A	332_A	1.277	1.00
70_V	74_K	1.267	1.00
388_V	434_S	1.262	1.00
201_V	205_L	1.262	1.00
187_T	190_A	1.260	1.00
307_T	310_E	1.256	1.00
255_K	258_D	1.255	1.00
9_K	244_E	1.254	1.00
84_G	87_D	1.253	1.00
517_A	521_E	1.251	1.00
520_K	524_K	1.251	1.00
221_A	234_V	1.249	1.00
246_S	250_N	1.245	1.00
443_I	447_K	1.242	1.00
363_Q	367_K	1.241	1.00
304_D	307_T	1.238	1.00
364_S	462_E	1.237	1.00
475_D	478_K	1.237	1.00
454_R	457_E	1.235	1.00
347_G	477_F	1.233	1.00
381_Q	444_E	1.228	1.00
140_F	143_Q	1.220	1.00
367_K	370_E	1.219	1.00
372_I	453_A	1.216	1.00
360_A	462_E	1.214	1.00
183_Q	186_F	1.212	1.00
149_S	153_T	1.211	1.00
535_E	538_A	1.210	1.00
496_A	499_T	1.208	1.00
95_K	98_D	1.208	1.00
22_I	200_S	1.198	1.00
283_E	286_Q	1.195	1.00
175_Q	179_A	1.195	1.00
220_S	223_E	1.194	1.00
342_S	345_D	1.191	1.00
56_S	59_Y	1.189	1.00
112_N	115_K	1.188	1.00
365_I	463_A	1.184	1.00
358_M	466_G	1.184	1.00
128_E	131_A	1.177	1.00
478_K	482_A	1.176	1.00
385_I	441_L	1.174	1.00
133_V	138_K	1.170	1.00
268_L	272_S	1.169	1.00
319_A	505_A	1.168	1.00
160_D	164_N	1.168	1.00
130_I	134_L	1.161	1.00
60_I	63_V	1.161	1.00
272_S	275_Q	1.160	1.00
371_I	455_S	1.159	1.00
496_A	500_N	1.151	1.00
262_T	265_Q	1.151	1.00
216_N	219_K	1.150	1.00
236_D	247_V	1.150	1.00
261_Q	265_Q	1.146	1.00
506_H	510_D	1.134	1.00
363_Q	366_Q	1.134	1.00
21_V	200_S	1.133	1.00
482_A	486_E	1.133	1.00
376_D	450_N	1.133	1.00
205_L	209_R	1.131	1.00
176_S	180_S	1.127	1.00
79_Q	83_N	1.126	1.00
353_N	469_M	1.126	1.00
234_V	250_N	1.125	1.00
447_K	451_R	1.123	1.00
202_I	206_V	1.121	1.00
341_Q	345_D	1.120	1.00
219_K	223_E	1.118	1.00
88_I	91_L	1.116	1.00
401_L	409_R	1.113	1.00
47_E	51_G	1.113	1.00
10_L	242_L	1.109	1.00
15_L	19_F	1.109	1.00
362_H	467_V	1.107	1.00
188_Q	191_I	1.106	1.00
499_T	503_A	1.104	1.00
107_T	113_V	1.103	1.00
236_D	246_S	1.103	1.00
217_A	220_S	1.099	1.00
265_Q	269_Q	1.097	1.00
318_Q	321_A	1.096	1.00
82_I	86_E	1.096	1.00
8_M	12_T	1.093	1.00
328_A	331_A	1.091	1.00
305_Q	519_I	1.090	1.00
59_Y	62_D	1.089	1.00
224_S	252_M	1.084	1.00
234_V	246_S	1.079	1.00
11_G	208_T	1.079	1.00
314_S	318_Q	1.079	1.00
219_K	245_L	1.075	1.00
38_T	42_K	1.074	1.00
349_K	352_A	1.069	1.00
122_G	126_S	1.068	1.00
309_I	515_N	1.066	1.00
44_M	50_K	1.064	1.00
214_R	238_T	1.062	1.00
370_E	374_Q	1.054	1.00
531_A	535_E	1.053	1.00
541_E	545_A	1.052	1.00
489_A	493_D	1.051	1.00
492_S	496_A	1.049	1.00
215_L	245_L	1.048	1.00
74_K	78_G	1.048	1.00
68_W	72_N	1.046	1.00
370_E	373_H	1.044	1.00
440_K	444_E	1.043	1.00
221_A	249_Y	1.040	1.00
101_T	104_Q	1.036	1.00
444_E	448_D	1.034	1.00
359_D	363_Q	1.033	1.00
361_I	463_A	1.033	1.00
305_Q	309_I	1.031	1.00
35_K	38_T	1.026	1.00
542_E	545_A	1.019	1.00
150_S	153_T	1.019	1.00
348_Q	478_K	1.017	1.00
366_Q	464_A	1.015	1.00
53_L	57_S	1.015	1.00
119_R	122_G	1.012	1.00
436_G	439_S	1.012	1.00
354_V	473_T	1.012	1.00
271_A	275_Q	1.002	1.00
141_Y	144_A	0.997	1.00
258_D	261_Q	0.996	1.00
357_Q	465_E	0.996	1.00
517_A	520_K	0.996	1.00
230_M	256_L	0.994	1.00
356_A	360_A	0.993	1.00
27_A	31_T	0.993	1.00
249_Y	252_M	0.989	1.00
437_Q	440_K	0.984	1.00
230_M	260_I	0.983	1.00
531_A	534_E	0.978	1.00
93_G	97_G	0.976	1.00
224_S	227_N	0.976	1.00
215_L	242_L	0.976	1.00
468_T	471_Q	0.974	1.00
538_A	542_E	0.968	1.00
34_L	182_T	0.967	1.00
489_A	492_S	0.966	1.00
179_A	183_Q	0.960	1.00
376_D	380_K	0.959	1.00
37_I	41_M	0.956	1.00
510_D	513_A	0.952	1.00
321_A	325_D	0.950	1.00
157_P	161_Q	0.949	1.00
510_D	514_A	0.948	1.00
158_L	162_N	0.947	1.00
91_L	94_E	0.947	1.00
374_Q	451_R	0.946	1.00
44_M	48_K	0.945	1.00
18_V	21_V	0.944	1.00
235_S	250_N	0.943	1.00
310_E	314_S	0.940	1.00
239_G	243_S	0.939	1.00
451_R	454_R	0.938	1.00
216_N	220_S	0.936	1.00
368_S	459_V	0.936	1.00
101_T	105_G	0.932	1.00
83_N	86_E	0.930	1.00
151_Y	161_Q	0.929	1.00
58_T	61_D	0.926	1.00
390_T	394_D	0.926	1.00
92_L	96_T	0.925	1.00
368_S	455_S	0.925	1.00
347_G	466_G	0.922	1.00
72_N	75_L	0.919	1.00
366_Q	460_K	0.918	1.00
35_K	39_E	0.917	1.00
463_A	466_G	0.916	1.00
8_M	16_C	0.915	1.00
50_K	54_A	0.914	1.00
70_V	73_N	0.912	1.00
70_V	78_G	0.910	1.00
73_N	76_Y	0.909	1.00
33_M	189_F	0.909	1.00
373_H	376_D	0.908	1.00
391_Q	430_E	0.908	1.00
344_A	347_G	0.908	1.00
286_Q	289_E	0.905	1.00
369_G	460_K	0.904	1.00
104_Q	108_R	0.904	1.00
206_V	209_R	0.902	1.00
348_Q	352_A	0.902	1.00
10_L	215_L	0.902	1.00
73_N	77_K	0.900	1.00
360_A	363_Q	0.899	1.00
247_V	250_N	0.899	1.00
26_S	29_V	0.897	1.00
38_T	182_T	0.896	1.00
359_D	471_Q	0.895	1.00
194_V	198_M	0.894	1.00
151_Y	155_Y	0.894	1.00
17_L	21_V	0.893	1.00
151_Y	154_A	0.891	1.00
147_A	153_T	0.887	1.00
251_K	255_K	0.885	1.00
422_D	426_K	0.885	1.00
385_I	442_I	0.885	1.00
356_A	359_D	0.884	1.00
518_D	522_S	0.884	1.00
134_L	137_G	0.881	1.00
52_D	56_S	0.881	1.00
251_K	254_M	0.878	1.00
529_A	536_Q	0.877	1.00
146_V	153_T	0.877	1.00
242_L	246_S	0.876	1.00
277_L	281_A	0.876	1.00
178_L	182_T	0.876	1.00
220_S	224_S	0.876	1.00
214_R	242_L	0.875	1.00
163_G	166_I	0.874	1.00
34_L	37_I	0.873	1.00
228_G	252_M	0.872	1.00
447_K	450_N	0.870	1.00
36_E	39_E	0.869	1.00
379_S	385_I	0.867	1.00
249_Y	253_R	0.867	1.00
127_S	131_A	0.865	1.00
180_S	184_S	0.863	1.00
259_T	263_V	0.863	1.00
122_G	125_A	0.862	1.00
146_V	151_Y	0.861	1.00
358_M	361_I	0.860	1.00
391_Q	394_D	0.860	1.00
154_A	157_P	0.859	1.00
213_K	217_A	0.859	1.00
80_T	83_N	0.856	1.00
210_K	214_R	0.856	1.00
74_K	77_K	0.856	1.00
118_E	121_V	0.856	1.00
225_A	249_Y	0.856	1.00
153_T	157_P	0.856	1.00
379_S	445_I	0.854	1.00
477_F	480_I	0.854	1.00
347_G	480_I	0.853	1.00
503_A	507_Q	0.852	1.00
462_E	465_E	0.852	1.00
221_A	232_I	0.849	1.00
304_D	308_R	0.848	1.00
222_F	225_A	0.847	1.00
99_T	112_N	0.847	1.00
227_N	255_K	0.847	1.00
317_K	509_N	0.846	1.00
17_L	200_S	0.845	1.00
232_I	253_R	0.844	1.00
365_I	456_V	0.843	1.00
432_Q	436_G	0.841	1.00
75_L	79_Q	0.839	1.00
147_A	150_S	0.839	1.00
30_G	34_L	0.839	1.00
323_I	498_V	0.838	1.00
312_S	508_I	0.838	1.00
449_M	452_S	0.830	1.00
314_S	317_K	0.829	1.00
446_Q	450_N	0.829	1.00
107_T	111_T	0.829	1.00
96_T	99_T	0.827	1.00
45_A	51_G	0.823	1.00
152_Q	159_K	0.819	1.00
430_E	437_Q	0.819	1.00
236_D	243_S	0.818	1.00
61_D	64_M	0.816	1.00
156_M	160_D	0.816	1.00
326_I	484_T	0.813	1.00
212_N	216_N	0.812	1.00
486_E	490_E	0.810	1.00
41_M	44_M	0.810	1.00
324_R	506_H	0.809	1.00
279_A	282_E	0.809	1.00
43_Q	47_E	0.808	1.00
11_G	212_N	0.808	1.00
217_A	221_A	0.807	1.00
211_I	214_R	0.805	1.00
430_E	433_Q	0.805	1.00
449_M	453_A	0.803	1.00
80_T	84_G	0.802	1.00
368_S	456_V	0.802	1.00
158_L	161_Q	0.800	1.00
374_Q	378_R	0.795	1.00
385_I	388_V	0.795	1.00
59_Y	63_V	0.793	1.00
241_E	244_E	0.789	1.00
384_Q	388_V	0.788	1.00
277_L	288_S	0.788	1.00
281_A	285_N	0.788	1.00
170_Y	174_N	0.787	1.00
285_N	289_E	0.787	1.00
263_V	267_A	0.784	1.00
340_A	484_T	0.783	1.00
98_D	101_T	0.783	1.00
103_F	106_D	0.781	1.00
146_V	150_S	0.780	1.00
394_D	405_I	0.779	1.00
152_Q	156_M	0.778	1.00
188_Q	192_V	0.777	1.00
326_I	498_V	0.775	1.00
440_K	443_I	0.774	1.00
263_V	266_S	0.773	1.00
369_G	457_E	0.773	1.00
198_M	202_I	0.771	1.00
48_K	51_G	0.770	1.00
22_I	204_V	0.767	1.00
227_N	251_K	0.764	1.00
232_I	236_D	0.763	1.00
81_Q	84_G	0.763	1.00
364_S	367_K	0.762	1.00
107_T	110_A	0.761	1.00
33_M	37_I	0.759	1.00
261_Q	264_Q	0.759	1.00
60_I	64_M	0.757	1.00
283_E	287_A	0.756	1.00
159_K	163_G	0.755	1.00
73_N	78_G	0.755	1.00
320_S	509_N	0.753	1.00
41_M	45_A	0.752	1.00
386_L	390_T	0.751	1.00
260_I	263_V	0.751	1.00
70_V	75_L	0.747	1.00
65_S	69_Q	0.745	1.00
285_N	288_S	0.745	1.00
397_N	425_R	0.745	1.00
184_S	187_T	0.745	1.00
385_I	434_S	0.744	1.00
101_T	170_Y	0.740	1.00
57_S	61_D	0.738	1.00
145_D	148_G	0.737	1.00
381_Q	441_L	0.735	1.00
521_E	525_N	0.734	1.00
164_N	167_G	0.734	1.00
40_S	44_M	0.733	1.00
79_Q	82_I	0.733	1.00
369_G	456_V	0.732	1.00
221_A	224_S	0.731	1.00
145_D	149_S	0.731	1.00
93_G	96_T	0.730	1.00
46_T	50_K	0.730	1.00
76_Y	81_Q	0.727	1.00
210_K	213_K	0.726	1.00
216_N	244_E	0.725	1.00
365_I	459_V	0.722	1.00
77_K	81_Q	0.720	1.00
89_V	93_G	0.719	1.00
108_R	112_N	0.719	1.00
57_S	64_M	0.717	1.00
538_A	541_E	0.717	1.00
343_K	346_I	0.716	1.00
319_A	501_I	0.712	1.00
171_T	174_N	0.712	1.00
252_M	256_L	0.710	1.00
213_K	216_N	0.708	1.00
351_I	470_I	0.705	1.00
344_A	348_Q	0.705	1.00
321_A	324_R	0.704	1.00
431_S	441_L	0.703	1.00
59_Y	64_M	0.700	1.00
155_Y	158_L	0.700	1.00
45_A	50_K	0.700	1.00
10_L	241_E	0.700	1.00
522_S	525_N	0.699	1.00
384_Q	437_Q	0.698	1.00
365_I	368_S	0.696	1.00
507_Q	511_S	0.695	1.00
240_D	246_S	0.694	1.00
177_I	181_L	0.693	1.00
509_N	513_A	0.693	1.00
500_N	504_S	0.692	1.00
332_A	490_E	0.691	1.00
49_A	53_L	0.690	1.00
312_S	512_F	0.688	1.00
316_L	512_F	0.688	1.00
375_L	385_I	0.688	1.00
341_Q	488_S	0.686	1.00
382_I	442_I	0.686	1.00
169_L	173_A	0.686	1.00
225_A	256_L	0.684	1.00
331_A	499_T	0.683	1.00
65_S	68_W	0.683	1.00
143_Q	147_A	0.681	1.00
281_A	288_S	0.680	1.00
268_L	271_A	0.679	1.00
104_Q	107_T	0.678	1.00
31_T	34_L	0.674	1.00
259_T	262_T	0.673	1.00
133_V	137_G	0.673	1.00
315_S	318_Q	0.673	1.00
353_N	472_R	0.672	1.00
350_E	472_R	0.670	1.00
226_G	251_K	0.670	1.00
140_F	155_Y	0.667	1.00
313_E	318_Q	0.667	1.00
262_T	266_S	0.665	1.00
69_Q	72_N	0.664	1.00
30_G	193_L	0.664	1.00
131_A	137_G	0.663	1.00
55_L	59_Y	0.663	1.00
84_G	88_I	0.661	1.00
155_Y	159_K	0.661	1.00
351_I	473_T	0.661	1.00
413_Q	418_A	0.661	1.00
327_S	330_T	0.660	1.00
357_Q	469_M	0.659	1.00
200_S	204_V	0.659	1.00
179_A	182_T	0.657	1.00
157_P	160_D	0.657	1.00
58_T	62_D	0.655	1.00
495_S	498_V	0.654	1.00
226_G	248_Y	0.653	1.00
100_I	103_F	0.653	1.00
473_T	476_A	0.652	1.00
539_A	542_E	0.651	1.00
543_I	547_S	0.651	1.00
108_R	111_T	0.650	1.00
208_T	211_I	0.649	1.00
236_D	240_D	0.649	1.00
166_I	169_L	0.648	1.00
18_V	204_V	0.647	1.00
325_D	493_D	0.646	1.00
43_Q	46_T	0.645	1.00
54_A	57_S	0.645	1.00
394_D	432_Q	0.644	1.00
110_A	113_V	0.644	1.00
266_S	269_Q	0.642	1.00
516_T	520_K	0.641	1.00
351_I	354_V	0.639	1.00
148_G	151_Y	0.637	1.00
120_A	123_T	0.636	1.00
167_G	171_T	0.636	1.00
218_L	242_L	0.635	1.00
358_M	467_V	0.635	1.00
506_H	509_N	0.635	1.00
532_L	535_E	0.635	1.00
494_L	497_S	0.634	1.00
77_K	82_I	0.634	1.00
39_E	42_K	0.634	1.00
133_V	136_K	0.634	1.00
196_V	200_S	0.633	1.00
123_T	126_S	0.633	1.00
99_T	113_V	0.632	1.00
45_A	48_K	0.631	1.00
428_A	431_S	0.630	1.00
85_N	92_L	0.629	1.00
380_K	384_Q	0.629	1.00
469_M	472_R	0.629	1.00
151_Y	159_K	0.627	1.00
214_R	240_D	0.627	1.00
238_T	242_L	0.626	1.00
354_V	470_I	0.625	1.00
159_K	162_N	0.625	1.00
121_V	125_A	0.624	1.00
148_G	153_T	0.624	1.00
94_E	97_G	0.623	1.00
12_T	16_C	0.623	1.00
317_K	320_S	0.622	1.00
131_A	134_L	0.621	1.00
212_N	242_L	0.621	1.00
111_T	115_K	0.620	1.00
312_S	316_L	0.620	1.00
425_R	429_E	0.620	1.00
172_G	176_S	0.619	1.00
161_Q	164_N	0.619	1.00
334_A	338_Q	0.618	1.00
330_T	333_I	0.618	1.00
27_A	193_L	0.618	1.00
195_I	199_V	0.617	1.00
394_D	398_L	0.617	1.00
24_L	196_V	0.616	1.00
72_N	76_Y	0.615	1.00
385_I	431_S	0.615	1.00
312_S	511_S	0.615	1.00
252_M	255_K	0.615	1.00
221_A	225_A	0.613	1.00
525_N	528_Q	0.613	1.00
371_I	448_D	0.612	1.00
390_T	436_G	0.609	1.00
386_L	439_S	0.608	1.00
77_K	80_T	0.605	1.00
139_R	143_Q	0.604	1.00
90_D	93_G	0.603	1.00
191_I	194_V	0.602	1.00
545_A	548_E	0.601	1.00
318_Q	322_D	0.598	1.00
360_A	465_E	0.598	1.00
270_L	274_S	0.597	1.00
357_Q	462_E	0.596	1.00
277_L	280_G	0.596	1.00
130_I	133_V	0.595	1.00
91_L	95_K	0.594	1.00
323_I	501_I	0.594	1.00
78_G	82_I	0.593	1.00
147_A	151_Y	0.592	1.00
336_K	486_E	0.592	1.00
12_T	15_L	0.592	1.00
146_V	149_S	0.591	1.00
98_D	102_I	0.588	1.00
270_L	273_A	0.588	1.00
36_E	40_S	0.588	1.00
228_G	259_T	0.587	1.00
385_I	435_A	0.587	1.00
71_K	78_G	0.585	1.00
176_S	179_A	0.584	1.00
186_F	189_F	0.583	1.00
308_R	511_S	0.582	1.00
443_I	446_Q	0.582	1.00
274_S	277_L	0.581	1.00
42_K	45_A	0.580	1.00
238_T	241_E	0.579	1.00
153_T	161_Q	0.579	1.00
228_G	245_L	0.578	1.00
269_Q	272_S	0.577	1.00
444_E	447_K	0.576	1.00
337_G	484_T	0.575	1.00
387_S	390_T	0.574	1.00
362_H	464_A	0.573	1.00
52_D	55_L	0.571	1.00
452_S	459_V	0.570	1.00
496_A	503_A	0.569	1.00
519_I	526_T	0.569	1.00
68_W	71_K	0.568	1.00
181_L	185_L	0.567	1.00
177_I	180_S	0.567	1.00
529_A	532_L	0.567	1.00
262_T	542_E	0.564	1.00
341_Q	485_G	0.563	1.00
346_I	472_R	0.563	1.00
219_K	242_L	0.563	1.00
379_S	446_Q	0.562	1.00
10_L	211_I	0.561	1.00
372_I	376_D	0.561	1.00
108_R	113_V	0.561	1.00
234_V	252_M	0.561	1.00
99_T	102_I	0.561	1.00
156_M	159_K	0.560	1.00
185_L	189_F	0.560	1.00
375_L	449_M	0.559	1.00
148_G	152_Q	0.559	1.00
145_D	151_Y	0.559	1.00
452_S	456_V	0.558	1.00
162_N	166_I	0.557	1.00
8_M	13_K	0.556	1.00
221_A	246_S	0.556	1.00
333_I	340_A	0.555	1.00
151_Y	156_M	0.552	1.00
347_G	473_T	0.552	1.00
530_A	534_E	0.552	1.00
134_L	138_K	0.551	1.00
320_S	323_I	0.550	1.00
15_L	208_T	0.549	1.00
28_S	31_T	0.549	1.00
155_Y	162_N	0.548	1.00
343_K	483_A	0.548	1.00
76_Y	85_N	0.548	1.00
512_F	516_T	0.547	1.00
39_E	43_Q	0.546	1.00
214_R	218_L	0.546	1.00
100_I	104_Q	0.544	1.00
544_T	548_E	0.543	1.00
445_I	449_M	0.543	1.00
10_L	13_K	0.543	1.00
400_A	425_R	0.541	1.00
152_Q	157_P	0.538	1.00
481_A	485_G	0.537	1.00
474_R	478_K	0.536	1.00
316_L	508_I	0.536	1.00
225_A	234_V	0.536	1.00
277_L	284_T	0.536	1.00
99_T	103_F	0.535	1.00
470_I	474_R	0.535	1.00
154_A	159_K	0.535	1.00
267_A	270_L	0.534	1.00
252_M	257_N	0.534	1.00
505_A	508_I	0.532	1.00
339_L	343_K	0.530	1.00
519_I	523_T	0.530	1.00
308_R	311_N	0.530	1.00
540_M	543_I	0.530	1.00
354_V	456_V	0.530	1.00
72_N	85_N	0.529	1.00
34_L	38_T	0.529	1.00
165_I	169_L	0.529	1.00
214_R	243_S	0.528	1.00
353_N	465_E	0.527	1.00
245_L	249_Y	0.526	1.00
174_N	177_I	0.525	1.00
330_T	491_I	0.524	1.00
278_S	281_A	0.524	1.00
331_A	485_G	0.523	1.00
398_L	405_I	0.522	1.00
310_E	516_T	0.520	1.00
131_A	136_K	0.519	1.00
360_A	458_H	0.518	1.00
195_I	202_I	0.518	1.00
318_Q	504_S	0.515	1.00
413_Q	424_V	0.515	1.00
329_N	490_E	0.513	1.00
360_A	364_S	0.513	1.00
263_V	270_L	0.512	1.00
17_L	24_L	0.511	1.00
202_I	205_L	0.510	1.00
138_K	142_G	0.510	1.00
243_S	247_V	0.508	1.00
367_K	455_S	0.508	1.00
358_M	470_I	0.507	1.00
214_R	217_A	0.506	1.00
111_T	114_M	0.505	1.00
148_G	155_Y	0.504	1.00
181_L	184_S	0.504	1.00
230_M	252_M	0.503	1.00
85_N	89_V	0.502	1.00
536_Q	540_M	0.502	1.00
167_G	170_Y	0.501	1.00
424_V	430_E	0.501	1.00
225_A	230_M	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.5288	100	0.428	Contact Map
2ch7A	2	0.5393	100	0.519	Contact Map
1qu7A	2	0.3962	100	0.557	Contact Map
3g67A	2	0.3647	100	0.615	Contact Map
4i3mA	2	0.2565	99.9	0.757	Contact Map
4cq4A	4	0.1501	99.8	0.8	Contact Map
2f95B	2	0.0925	99.4	0.848	Contact Map
4gycB	2	0.1065	99.2	0.862	Contact Map
3zccA	2	0.1902	98.8	0.883	Contact Map
4i5sA	2	0.5654	98.5	0.894	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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