GLYA - BACSU - GREMLIN Contacts

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GLYA - Serine hydroxymethyltransferase

UniProt:	P39148	Sequences: MKHLPAQDEQVFNAIKNERERQQTKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRAKEIFGAEHVNVQPHSGAQANMAVYFTILEQGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDKETQYIDYDDVREKALAHKPKLIVAGASAYPRTIDFKKFREIADEVGAYFMVDMAHIAGLVAAGLHPNPVPYADFVTTTTHKTLRGPRGGMILCREEFGKKIDKSIFPGIQGGPLMHVIAAKAVSFGEVLQDDFKTYAQNVISNAKRLAEALTKEGIQLVSGGTDNHLILVDLRSLGLTGKVAEHVLDEIGITSNKNAIPYDPEKPFVTSGIRLGTAAVTSRGFDGDALEEVGAIIALALKNHEDEGKLEEARQRVAALTDKFPLYKELDY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	415 (407)
Sequences:	4084 (1815)
Seq/√Len:	90.0

ECOLI - GLYA
BACSU - GLYA
HALSA - GLYA
SULSO - GLYA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
184_R	188_D	4.426	1.00
156_R	189_E	4.371	1.00
72_D	76_D	3.318	1.00
160_L	189_E	3.226	1.00
105_I	219_F	3.127	1.00
177_T	211_P	2.929	1.00
287_S	370_G	2.928	1.00
148_Q	302_Q	2.904	1.00
150_I	155_V	2.898	1.00
111_T	137_N	2.869	1.00
154_D	157_E	2.853	1.00
78_A	235_M	2.836	1.00
222_T	235_M	2.731	1.00
144_D	147_T	2.652	1.00
156_R	182_K	2.635	1.00
17_N	69_V	2.624	1.00
375_E	399_R	2.602	1.00
156_R	160_L	2.599	1.00
327_A	384_L	2.567	1.00
382_L	399_R	2.529	1.00
369_D	372_A	2.515	1.00
26_I	363_V	2.509	1.00
157_E	161_A	2.414	1.00
284_N	369_D	2.407	1.00
271_G	275_Q	2.389	1.00
181_K	185_E	2.388	1.00
158_K	162_H	2.366	1.00
111_T	162_H	2.304	1.00
207_A	282_A	2.299	1.00
283_Q	287_S	2.276	1.00
284_N	370_G	2.250	1.00
209_L	286_I	2.248	1.00
294_E	298_K	2.205	1.00
14_A	69_V	2.190	1.00
87_V	237_L	2.177	1.00
78_A	222_T	2.090	1.00
368_F	376_V	2.055	1.00
295_A	377_G	2.052	1.00
383_A	396_A	2.027	1.00
176_R	309_D	2.021	1.00
299_E	378_A	2.008	1.00
196_V	217_A	2.004	1.00
155_V	183_F	2.003	1.00
338_S	358_L	1.983	1.00
175_P	303_L	1.969	1.00
72_D	75_R	1.968	1.00
379_I	396_A	1.967	1.00
295_A	298_K	1.940	1.00
301_I	381_A	1.935	1.00
299_E	381_A	1.930	1.00
139_V	162_H	1.930	1.00
363_V	373_L	1.929	1.00
86_H	238_C	1.924	1.00
112_V	138_F	1.882	1.00
43_Q	262_V	1.858	1.00
86_H	247_D	1.838	1.00
14_A	70_V	1.835	1.00
295_A	378_A	1.819	1.00
76_D	80_E	1.799	1.00
295_A	374_E	1.795	1.00
106_L	166_L	1.788	1.00
201_I	210_H	1.778	1.00
238_C	243_G	1.726	1.00
321_G	348_E	1.718	1.00
111_T	139_V	1.702	1.00
386_N	389_D	1.688	1.00
284_N	287_S	1.672	1.00
34_F	409_L	1.648	1.00
372_A	407_F	1.638	1.00
154_D	158_K	1.634	1.00
95_A	124_T	1.617	1.00
17_N	66_H	1.613	1.00
28_L	363_V	1.612	1.00
291_R	295_A	1.608	1.00
36_S	272_E	1.604	1.00
169_A	183_F	1.582	1.00
86_H	243_G	1.581	1.00
66_H	69_V	1.562	1.00
292_L	373_L	1.548	1.00
11_V	70_V	1.543	1.00
152_Y	182_K	1.538	1.00
318_R	348_E	1.535	1.00
288_N	364_T	1.535	1.00
183_F	194_F	1.524	1.00
43_Q	265_A	1.517	1.00
80_E	274_L	1.499	1.00
289_A	308_T	1.494	1.00
209_L	282_A	1.491	1.00
218_D	239_R	1.491	1.00
375_E	379_I	1.485	1.00
292_L	377_G	1.478	1.00
102_Y	168_V	1.476	1.00
279_K	283_Q	1.453	0.99
395_E	399_R	1.430	0.99
19_R	23_Q	1.422	0.99
243_G	247_D	1.421	0.99
371_D	374_E	1.412	0.99
47_L	70_V	1.405	0.99
11_V	268_V	1.403	0.99
292_L	296_L	1.398	0.99
118_S	342_A	1.391	0.99
293_A	313_I	1.391	0.99
99_M	131_F	1.386	0.99
381_A	385_K	1.380	0.99
333_E	393_L	1.357	0.99
85_E	239_R	1.356	0.99
166_L	195_M	1.352	0.99
201_I	310_N	1.350	0.99
209_L	283_Q	1.340	0.99
87_V	235_M	1.338	0.99
330_V	387_H	1.337	0.99
295_A	299_E	1.334	0.99
14_A	66_H	1.333	0.99
84_A	214_V	1.333	0.99
334_I	383_A	1.332	0.99
81_I	273_V	1.331	0.99
78_A	270_F	1.324	0.99
198_M	237_L	1.311	0.99
20_E	24_T	1.311	0.99
25_K	332_D	1.305	0.99
368_F	373_L	1.303	0.99
145_K	345_Y	1.302	0.99
301_I	320_L	1.302	0.99
212_N	215_P	1.296	0.99
138_F	168_V	1.295	0.99
105_I	242_F	1.284	0.99
222_T	270_F	1.279	0.99
210_H	310_N	1.273	0.99
302_Q	316_D	1.271	0.99
144_D	151_D	1.266	0.99
320_L	385_K	1.262	0.98
335_G	401_A	1.253	0.98
52_A	260_M	1.250	0.98
280_T	283_Q	1.247	0.98
379_I	399_R	1.237	0.98
392_K	396_A	1.234	0.98
208_G	279_K	1.229	0.98
242_F	245_K	1.229	0.98
106_L	110_D	1.218	0.98
334_I	396_A	1.210	0.98
139_V	158_K	1.195	0.98
13_N	17_N	1.192	0.98
101_V	219_F	1.184	0.98
25_K	335_G	1.184	0.98
293_A	303_L	1.184	0.98
383_A	393_L	1.182	0.98
143_V	345_Y	1.177	0.98
322_L	384_L	1.174	0.98
57_G	72_D	1.169	0.98
294_E	374_E	1.167	0.97
100_A	250_I	1.167	0.97
47_L	67_V	1.166	0.97
35_V	40_M	1.163	0.97
153_D	182_K	1.161	0.97
27_E	337_T	1.159	0.97
363_V	376_V	1.157	0.97
302_Q	319_S	1.156	0.97
342_A	346_D	1.156	0.97
180_F	210_H	1.152	0.97
299_E	382_L	1.147	0.97
107_E	110_D	1.143	0.97
169_A	196_V	1.139	0.97
7_Q	271_G	1.135	0.97
110_D	165_K	1.134	0.97
195_M	221_T	1.128	0.97
24_T	401_A	1.124	0.97
188_D	218_D	1.122	0.97
193_Y	242_F	1.120	0.97
74_A	267_A	1.106	0.97
156_R	185_E	1.103	0.96
182_K	185_E	1.100	0.96
144_D	154_D	1.099	0.96
26_I	368_F	1.095	0.96
86_H	246_I	1.095	0.96
375_E	406_K	1.094	0.96
338_S	356_I	1.093	0.96
86_H	239_R	1.090	0.96
218_D	240_E	1.088	0.96
318_R	347_P	1.087	0.96
299_E	374_E	1.087	0.96
19_R	410_Y	1.086	0.96
290_K	294_E	1.082	0.96
218_D	242_F	1.073	0.96
12_F	16_K	1.073	0.96
105_I	193_Y	1.070	0.96
378_A	382_L	1.065	0.96
62_G	328_E	1.065	0.96
171_A	178_I	1.058	0.95
287_S	369_D	1.054	0.95
5_P	12_F	1.050	0.95
11_V	14_A	1.050	0.95
67_V	260_M	1.048	0.95
107_E	165_K	1.046	0.95
296_L	381_A	1.046	0.95
297_T	306_G	1.045	0.95
152_Y	155_V	1.044	0.95
115_M	142_G	1.043	0.95
291_R	374_E	1.033	0.95
333_E	390_E	1.030	0.95
85_E	240_E	1.030	0.95
184_R	218_D	1.029	0.95
114_G	124_T	1.024	0.95
379_I	403_L	1.020	0.95
177_T	210_H	1.017	0.94
198_M	205_V	1.013	0.94
52_A	64_C	1.011	0.94
239_R	242_F	1.010	0.94
181_K	216_Y	1.007	0.94
375_E	378_A	1.004	0.94
335_G	397_R	0.998	0.94
302_Q	306_G	0.993	0.94
348_E	352_V	0.991	0.94
334_I	393_L	0.991	0.94
113_L	139_V	0.987	0.93
169_A	194_F	0.987	0.93
137_N	162_H	0.981	0.93
231_P	265_A	0.978	0.93
382_L	395_E	0.977	0.93
116_N	140_E	0.975	0.93
299_E	385_K	0.975	0.93
330_V	383_A	0.974	0.93
323_T	348_E	0.970	0.93
398_Q	402_A	0.970	0.93
19_R	46_V	0.969	0.93
320_L	381_A	0.967	0.93
171_A	201_I	0.967	0.93
372_A	403_L	0.964	0.93
152_Y	183_F	0.961	0.93
84_A	237_L	0.957	0.92
173_A	314_L	0.957	0.92
8_D	77_R	0.956	0.92
250_I	254_I	0.955	0.92
331_L	338_S	0.953	0.92
99_M	254_I	0.953	0.92
104_T	249_S	0.949	0.92
11_V	47_L	0.948	0.92
85_E	238_C	0.942	0.92
144_D	345_Y	0.941	0.92
171_A	310_N	0.939	0.92
289_A	361_A	0.937	0.92
116_N	119_H	0.935	0.92
334_I	379_I	0.934	0.91
313_I	358_L	0.933	0.91
229_R	365_S	0.929	0.91
114_G	140_E	0.926	0.91
369_D	407_F	0.924	0.91
107_E	134_V	0.915	0.91
42_A	268_V	0.913	0.91
382_L	392_K	0.911	0.90
39_V	269_S	0.909	0.90
303_L	313_I	0.908	0.90
10_Q	271_G	0.904	0.90
241_E	245_K	0.902	0.90
103_F	136_Y	0.900	0.90
16_K	19_R	0.898	0.90
271_G	274_L	0.897	0.90
51_Y	225_H	0.897	0.90
235_M	270_F	0.897	0.90
193_Y	219_F	0.892	0.89
294_E	297_T	0.889	0.89
176_R	307_G	0.886	0.89
74_A	89_V	0.886	0.89
219_F	242_F	0.885	0.89
159_A	167_I	0.882	0.89
106_L	112_V	0.881	0.89
302_Q	343_I	0.881	0.89
131_F	135_Q	0.878	0.89
382_L	396_A	0.877	0.89
401_A	405_D	0.871	0.88
102_Y	112_V	0.867	0.88
9_E	12_F	0.865	0.88
14_A	17_N	0.863	0.88
372_A	406_K	0.862	0.88
387_H	393_L	0.860	0.88
181_K	184_R	0.860	0.88
329_H	333_E	0.860	0.88
160_L	163_K	0.858	0.88
83_G	208_G	0.858	0.88
15_I	42_A	0.856	0.87
282_A	285_V	0.855	0.87
394_E	398_Q	0.842	0.87
10_Q	13_N	0.838	0.86
96_Q	99_M	0.838	0.86
9_E	13_N	0.834	0.86
392_K	395_E	0.834	0.86
326_V	330_V	0.834	0.86
160_L	190_V	0.833	0.86
297_T	303_L	0.833	0.86
169_A	198_M	0.833	0.86
314_L	341_N	0.832	0.86
368_F	403_L	0.832	0.86
375_E	402_A	0.831	0.86
102_Y	138_F	0.827	0.86
178_I	183_F	0.826	0.86
118_S	346_D	0.824	0.85
301_I	315_V	0.823	0.85
167_I	183_F	0.816	0.85
221_T	236_I	0.816	0.85
61_Y	225_H	0.815	0.85
11_V	73_I	0.815	0.85
282_A	361_A	0.814	0.85
92_H	96_Q	0.809	0.84
158_K	161_A	0.809	0.84
289_A	313_I	0.807	0.84
169_A	217_A	0.805	0.84
323_T	326_V	0.804	0.84
368_F	407_F	0.804	0.84
78_A	237_L	0.803	0.84
128_P	138_F	0.803	0.84
175_P	313_I	0.802	0.84
150_I	178_I	0.795	0.83
398_Q	401_A	0.794	0.83
396_A	399_R	0.787	0.83
51_Y	61_Y	0.786	0.83
238_C	247_D	0.785	0.83
37_E	41_E	0.784	0.82
24_T	405_D	0.782	0.82
386_N	393_L	0.780	0.82
76_D	79_K	0.776	0.82
4_L	15_I	0.776	0.82
298_K	374_E	0.775	0.82
11_V	271_G	0.775	0.82
397_R	401_A	0.773	0.82
229_R	281_Y	0.772	0.81
291_R	370_G	0.767	0.81
346_D	349_K	0.766	0.81
101_V	195_M	0.766	0.81
386_N	392_K	0.766	0.81
296_L	377_G	0.766	0.81
101_V	106_L	0.765	0.81
383_A	392_K	0.765	0.81
273_V	278_F	0.763	0.81
69_V	72_D	0.761	0.81
238_C	246_I	0.760	0.80
15_I	47_L	0.760	0.80
184_R	194_F	0.759	0.80
116_N	142_G	0.757	0.80
368_F	372_A	0.756	0.80
360_T	373_L	0.752	0.80
326_V	388_E	0.752	0.80
181_K	215_P	0.747	0.79
155_V	186_I	0.745	0.79
157_E	160_L	0.745	0.79
299_E	377_G	0.745	0.79
215_P	220_V	0.743	0.79
377_G	381_A	0.743	0.79
75_R	79_K	0.743	0.79
278_F	285_V	0.742	0.79
201_I	205_V	0.741	0.79
78_A	87_V	0.737	0.78
113_L	140_E	0.736	0.78
280_T	284_N	0.730	0.78
95_A	250_I	0.728	0.78
106_L	195_M	0.726	0.77
295_A	381_A	0.719	0.77
4_L	41_E	0.718	0.77
24_T	335_G	0.717	0.76
238_C	242_F	0.715	0.76
79_K	87_V	0.715	0.76
9_E	38_A	0.711	0.76
101_V	221_T	0.711	0.76
84_A	220_V	0.708	0.76
115_M	178_I	0.708	0.76
85_E	242_F	0.707	0.75
245_K	248_K	0.707	0.75
131_F	136_Y	0.706	0.75
322_L	326_V	0.705	0.75
326_V	348_E	0.703	0.75
330_V	393_L	0.701	0.75
92_H	259_L	0.700	0.75
390_E	394_E	0.700	0.75
75_R	247_D	0.697	0.74
194_F	217_A	0.697	0.74
70_V	260_M	0.696	0.74
113_L	162_H	0.695	0.74
383_A	387_H	0.695	0.74
292_L	358_L	0.695	0.74
328_E	332_D	0.693	0.74
286_I	360_T	0.692	0.74
214_V	220_V	0.690	0.74
84_A	212_N	0.690	0.74
393_L	396_A	0.690	0.74
145_K	148_Q	0.689	0.74
325_K	351_F	0.688	0.73
231_P	269_S	0.686	0.73
7_Q	38_A	0.686	0.73
374_E	378_A	0.683	0.73
113_L	138_F	0.682	0.73
286_I	290_K	0.679	0.72
103_F	249_S	0.677	0.72
23_Q	410_Y	0.677	0.72
111_T	158_K	0.676	0.72
155_V	158_K	0.676	0.72
402_A	406_K	0.675	0.72
103_F	254_I	0.675	0.72
112_V	166_L	0.675	0.72
399_R	402_A	0.672	0.72
205_V	210_H	0.672	0.72
86_H	240_E	0.671	0.72
202_A	227_T	0.671	0.72
393_L	397_R	0.671	0.72
177_T	212_N	0.671	0.72
207_A	283_Q	0.670	0.71
180_F	201_I	0.669	0.71
102_Y	166_L	0.669	0.71
198_M	206_A	0.669	0.71
128_P	351_F	0.667	0.71
129_V	248_K	0.660	0.70
313_I	360_T	0.659	0.70
34_F	362_A	0.659	0.70
40_M	49_N	0.659	0.70
323_T	352_V	0.657	0.70
12_F	41_E	0.656	0.70
330_V	386_N	0.655	0.70
317_L	320_L	0.655	0.70
78_A	82_F	0.654	0.70
113_L	159_A	0.652	0.69
155_V	169_A	0.649	0.69
330_V	333_E	0.649	0.69
187_A	194_F	0.644	0.68
278_F	282_A	0.643	0.68
291_R	294_E	0.641	0.68
371_D	407_F	0.640	0.68
330_V	334_I	0.640	0.68
107_E	137_N	0.640	0.68
317_L	343_I	0.640	0.68
40_M	410_Y	0.639	0.68
402_A	405_D	0.638	0.68
332_D	335_G	0.638	0.68
187_A	192_A	0.638	0.68
395_E	398_Q	0.637	0.68
239_R	243_G	0.637	0.68
59_R	68_D	0.636	0.68
342_A	349_K	0.635	0.67
168_V	195_M	0.633	0.67
108_Q	135_Q	0.633	0.67
80_E	83_G	0.631	0.67
4_L	38_A	0.629	0.67
32_E	51_Y	0.628	0.67
154_D	162_H	0.628	0.67
269_S	273_V	0.627	0.66
326_V	387_H	0.627	0.66
51_Y	257_G	0.627	0.66
115_M	152_Y	0.626	0.66
272_E	281_Y	0.625	0.66
304_V	317_L	0.624	0.66
114_G	138_F	0.623	0.66
315_V	338_S	0.622	0.66
282_A	286_I	0.620	0.66
395_E	402_A	0.618	0.65
169_A	178_I	0.617	0.65
329_H	332_D	0.617	0.65
240_E	244_K	0.616	0.65
79_K	84_A	0.614	0.65
91_P	250_I	0.614	0.65
151_D	154_D	0.614	0.65
84_A	239_R	0.613	0.65
25_K	404_T	0.612	0.65
379_I	383_A	0.612	0.65
101_V	166_L	0.611	0.64
23_Q	409_L	0.610	0.64
35_V	39_V	0.609	0.64
175_P	305_S	0.608	0.64
390_E	393_L	0.607	0.64
296_L	303_L	0.605	0.64
284_N	364_T	0.604	0.64
204_L	286_I	0.604	0.64
249_S	254_I	0.603	0.63
65_E	332_D	0.602	0.63
386_N	390_E	0.601	0.63
295_A	373_L	0.600	0.63
317_L	321_G	0.598	0.63
73_I	271_G	0.598	0.63
7_Q	275_Q	0.596	0.63
301_I	385_K	0.596	0.63
229_R	272_E	0.595	0.62
17_N	20_E	0.595	0.62
181_K	188_D	0.595	0.62
135_Q	249_S	0.594	0.62
332_D	337_T	0.594	0.62
378_A	399_R	0.593	0.62
291_R	373_L	0.592	0.62
379_I	382_L	0.592	0.62
153_D	157_E	0.592	0.62
119_H	142_G	0.591	0.62
215_P	239_R	0.590	0.62
153_D	156_R	0.590	0.62
276_D	280_T	0.590	0.62
72_D	260_M	0.589	0.62
277_D	280_T	0.589	0.62
230_G	269_S	0.587	0.61
11_V	66_H	0.585	0.61
349_K	352_V	0.585	0.61
244_K	248_K	0.583	0.61
358_L	380_I	0.583	0.61
175_P	312_L	0.583	0.61
153_D	189_E	0.582	0.61
119_H	145_K	0.579	0.60
98_N	221_T	0.579	0.60
242_F	246_I	0.578	0.60
303_L	315_V	0.578	0.60
207_A	279_K	0.577	0.60
105_I	166_L	0.576	0.60
20_E	23_Q	0.576	0.60
124_T	138_F	0.575	0.60
270_F	274_L	0.573	0.60
366_R	408_P	0.573	0.60
10_Q	80_E	0.573	0.60
297_T	302_Q	0.572	0.59
231_P	262_V	0.571	0.59
363_V	368_F	0.571	0.59
394_E	397_R	0.566	0.59
95_A	130_N	0.565	0.58
95_A	99_M	0.564	0.58
266_K	270_F	0.562	0.58
85_E	243_G	0.561	0.58
148_Q	343_I	0.560	0.58
152_Y	178_I	0.560	0.58
196_V	237_L	0.560	0.58
81_I	270_F	0.560	0.58
60_Y	129_V	0.560	0.58
214_V	237_L	0.559	0.58
103_F	131_F	0.557	0.57
346_D	351_F	0.557	0.57
301_I	380_I	0.554	0.57
99_M	135_Q	0.551	0.57
14_A	47_L	0.551	0.57
196_V	201_I	0.551	0.57
331_L	356_I	0.550	0.56
205_V	310_N	0.550	0.56
36_S	281_Y	0.550	0.56
322_L	327_A	0.550	0.56
371_D	378_A	0.549	0.56
342_A	351_F	0.549	0.56
240_E	243_G	0.548	0.56
99_M	130_N	0.547	0.56
180_F	205_V	0.547	0.56
74_A	270_F	0.547	0.56
62_G	337_T	0.546	0.56
95_A	102_Y	0.545	0.56
35_V	265_A	0.545	0.56
372_A	375_E	0.544	0.56
156_R	186_I	0.544	0.56
286_I	289_A	0.544	0.56
179_D	182_K	0.543	0.55
73_I	77_R	0.543	0.55
185_E	189_E	0.542	0.55
53_E	59_R	0.541	0.55
224_T	233_G	0.540	0.55
218_D	243_G	0.540	0.55
43_Q	261_H	0.539	0.55
92_H	95_A	0.538	0.55
106_L	165_K	0.537	0.55
15_I	46_V	0.536	0.55
148_Q	301_I	0.535	0.54
285_V	360_T	0.534	0.54
331_L	380_I	0.534	0.54
290_K	309_D	0.534	0.54
33_N	281_Y	0.534	0.54
177_T	286_I	0.532	0.54
172_S	199_A	0.532	0.54
99_M	103_F	0.531	0.54
66_H	70_V	0.531	0.54
64_C	259_L	0.530	0.54
140_E	158_K	0.530	0.54
58_K	351_F	0.530	0.54
112_V	165_K	0.529	0.54
372_A	376_V	0.529	0.54
64_C	266_K	0.527	0.53
239_R	245_K	0.527	0.53
40_M	46_V	0.526	0.53
373_L	376_V	0.525	0.53
328_E	338_S	0.525	0.53
99_M	136_Y	0.525	0.53
403_L	410_Y	0.524	0.53
27_E	362_A	0.524	0.53
35_V	48_T	0.524	0.53
259_L	262_V	0.523	0.53
301_I	343_I	0.523	0.53
273_V	282_A	0.523	0.53
285_V	289_A	0.522	0.53
77_R	268_V	0.521	0.52
287_S	290_K	0.520	0.52
327_A	356_I	0.519	0.52
209_L	279_K	0.519	0.52
260_M	263_I	0.518	0.52
207_A	286_I	0.518	0.52
301_I	319_S	0.518	0.52
296_L	315_V	0.518	0.52
144_D	149_Y	0.517	0.52
315_V	320_L	0.516	0.52
25_K	65_E	0.515	0.52
129_V	349_K	0.512	0.51
32_E	225_H	0.512	0.51
92_H	266_K	0.511	0.51
199_A	221_T	0.510	0.51
159_A	186_I	0.509	0.51
225_H	257_G	0.509	0.51
323_T	353_T	0.509	0.51
103_F	135_Q	0.508	0.51
301_I	377_G	0.508	0.51
207_A	212_N	0.508	0.51
31_S	61_Y	0.507	0.51
287_S	291_R	0.506	0.50
83_G	214_V	0.505	0.50
44_G	48_T	0.505	0.50
96_Q	259_L	0.504	0.50
202_A	222_T	0.502	0.50
292_L	295_A	0.501	0.50
284_N	288_N	0.500	0.50

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1rv3A	3	0.9976	100	0.461	Contact Map
3ou5A	2	0.9157	100	0.489	Contact Map
3h7fA	2	0.9976	100	0.577	Contact Map
4wxgA	2	0.9831	100	0.593	Contact Map
3n0lA	2	0.959	100	0.619	Contact Map
3gbxA	2	0.9181	100	0.628	Contact Map
3ecdA	2	0.9108	100	0.628	Contact Map
2dkjA	2	0.9663	100	0.631	Contact Map
2vi8A	2	0.9759	100	0.637	Contact Map
4msoA	2	0.9253	100	0.641	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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